current user: public
If you have questions about the server, please let us know.

Query: [S] COG5644 Uncharacterized conserved protein, from COG1018

Results of FFAS03 search in PDB1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
    .   10    .   20    .   30    .   40    .   50    .   60    .   70    .   80    .   90    .  100    .  110    .  120    .  130    .  140    .  150    .  160    .  170    .  180    .  190    .  200    .  210    .  220    .  230    .  240    .  250    .  260    .  270    .  280    .  290    .  300    .  310    .  320    .  330    .  340    .  350    .  360    .  370    .  380    .  390    .  400    .  410    .  420    .  430    .  440    .  450    .  460    .  470    .  480    .  490    .  500    .  510    .  520    .  530    .  540    .  550    .  560    .  570    .  580    .  590    .  600    .  610    .  620    .  630    .  640    .  650    .  660    .  670    .  680    .  690    .  700    .  710    .  720    .  730    .  740    .  750    .  760    .  770    .  780    .  790    .  800    .  810    .  820    .  830    .  840    .  850    .  860    .  870    .  880    .  890    .  900    .  910    .  920    .
# Score Template Links and tools%idFirst MARKGKVNTLPQPQGKHQRKGKKQLENKILHSYEEESAGFDSEELEDNDEQGYSFGVNSEDDEEIDSDEAFDEEDEKRFADWSFNASKSGKSNKDHKNLNNTKEISLNEEDDSDDSVNSDKLENEGSVGSSIDENELVDLDTLLDNDQPEKNESNTASTIRPPWIGNNDHATDKENLLESDASSSNDSESELTDSADNMNESDSESEIESSDSDHDDGENSDSKLDNLRNYIVSLNQKRKKDEADAESVLSSDDNDSIEEISIKKVKYDPHETNKESEYNLIGSSEKTIDITDLLDSIPMNEQLKVSLKPLVSESSSISSKKLDAPLAKSIQDRLERQAAYEQTKNDLEKWKPIVADNRKSDQLIFPMNETARPVPSNNGLASSFEPRTESERKMHQALLDAGLENESALKKQEELALNKLSVEEVAERTRQLRFMRELMFREERKAKRVAKIKSKTYRKIRKNRKEKEMALIPKSEEDLENERIKSEEARALERMTQRHKNTSSWTRKMLERASHGEGTREAVNEQIRKGDELMQRIHGKEISEMDGEDVSEFSDSDYDTNEQVSTAFEKIRNEEEPKLKGVLGMKFMRDASNRQKALVQDEMQAFEDELAGVPNEDDTSQKGEDGVPGVLIGNNTGRRSFKPSEEAAKLSLPSRKNPFVSDSAVLKVNKPEMKEGQKKAEARKKKESPLEATEETNPWLQVPDQRTSSAKKLDKNSSKADKKNHKLKMDKVASLQELVEEPKVQPDLIFEEKAFESASEAESDVDVSVPMLKPTKGRLSIKQRELVAKAFAGDDVVAEFEKDKEDWVQEDAPKEEDHSLPGWGSWGGVGVKQRKTKPKVKKIAGLDPSKRKDSKLKHVIINEKRNKKAAKLTADSVPFPFESREQYERSLNLPMGPEWTTRASHHKAVAPRVVTKRGKVINPIKAPNLast
1 -124.0005oql_K mol:protein length:938 Utp14  ali model follow..  23  17.SSSGGGKSKKSRSKARRSAQSKALDAFALAAEQVPESRSKGVRLRDLDEHPSTSASRNKRQHEDDEEDDFDGFDDDE---------GMGRKKRARRDSGGDEDGDDVDEDMEGGADGEDDSEEWHVGVTGADEDSEIDSDEAFGESDEERFEGFVFGGSKSHKKGTKKRRNGSEDDAIDLATALDQYESSEEGEEGEESESEEDDEESEEEDSDEEDDDPSKLDALQSMIAGFAGEDEESGGEGEAKPSGKQKLSLK-------------------------------DLGLVGVKDPDMKRSLRLMKKEEKATKPGSSKKLEVPLAKRQQDRLMREAAYKKTNETLDRWIETVKHNRRAEHLVFPLAQNAHDRASELQPITQKTSGTELEQTILAIMEESGLGPTEKKETSGEAGKQGMSKEEQKELIRQKRRERELHSREMARLKRIKKIKSKTWRRIHRKELLKNQAALEAGELDSEEEREALDRRRALERVGARHKESKWAKLGKKARAVWDEDFRAGLAEMARRKDELRKRIEGLKNGSDDSSDDSDGDEDASGDEAAAELEKAAAYSDDDEPHSKLFQLKFMQRGEELRRKENEELIAQIRRELDSDYDGSEPDEVEIGRRTFGMGKKDKTEQQQAQDQLARMQAAEARKEKAAARVAAAEETVKQEAREKAEKDEASAPSTAGAWSQPKVEAKPRKAPKGRPEEIDVTDLALAGKPAKAKANGQAKSQVQGKAHASNGQSSSSQKASTSVAITGAEEDGNDSDDSDAVHLPMAIRDRALIERAFAGDDVAAEFEKEKAEIEADDDEKEIDNTLPGWGSWVGEGVSNREKRRHQTKVEGIKKEKRKDYKLKDVIINEKRVKKNDKYLATGLPHPFESQQQYERSLRLPVGPEWMTKETFQDATKPRVIIKQG-IIAPMSKP. 936
2 -15.9005z10_A mol:protein length:2547 Piezo-type mechanosensitive ion channel component 1  ali model follow..  10 1196................................................................................................................................................................................................................................................................................................................................................TTLLQKDTRAQLVLWDCLILYNKNMLSLLFSLVCTVKGYYDPKEMMTRDRDCLLPVEEAG-LLQRRIFLSHYFLHVSADLKATALQASRGFALYNAANL-KSINFHRQIEEKSLAQLKRQM-KRIRAKQEKYRQSQASRGQLQSKDPQDPSQEPGPDSPGGSSPPRRQWWRPWLDHATVIHSGDYFLFESDSEEEEEALPEDPRPAAQSAFQMAYQAWVTNAQTVLRQRRERARQERAEQLASGGDLNPDVEPVDVPEDEMAGRSHMMQRVLSTMQFLWVLGQATVDGLTRWLRAFTKHHRTMSDVLCAERYLLTQELLRVGEVRRGVLDQLYVGEDEATLSGPVETRDGPSTASSGLGAEEPLSSMTDDTSSPLSTGYNTRSGSEEIVTDAGDLQAGTSLHGSQELLANARTRMRTASELLLDRRLHIPELEEAERFEAQQGRTLRLLRAGYQCVAHSELLCYFIIILNHMVTAS----ASLVLP-WAMW-----------------------------MTAIVFTE-----VTKYLFQFGFFPWNSYVVLRRYENKPLGLEKTDSYIKYDLVQ-SQLLCYG.......... 1804
3 -11.5006ez8_A mol:protein length:3138 Huntingtin  ali model follow..  8  394.VGGIGQLTAAKEESGGRSRSGSIVELIAGGGSSCSPVLSRKQKGKVLLGEEEALEDDSESRSDVSSSALTASVKDEISGELAASSGVSTPGSAGHDIITEQPRSQHTLQADSVDLASCDLTSSATDGDEEDILSHSSSQVSAVPSDPAMDLNDGTQASSPISDSSQTTTEGPDSAVTPSDSSEIVLDGTDNQYLGLQIGQPQDEDEEATGILPDEASEAFRNSSMALQQAHLLKNMSHCRQPSDSSVDKFVLRDEATEPGDQENKPCRIKGDIGQSTDDDSAPLVHCVRLLSASFLLTGGKNVLVPDRDVRVSVKALALSCVGAAV------ALHPESFFSKLYKVPLDTTEYPEEQYVSDILNYIDHGDPQVRGATAILCGTL---------ICSILSRSRFHVGDWMGTIRTLTGNTFSLADCIPLRKTLKDESSVTCKLACTAIDVLTLRNSSYWLVRTELLETLAEIDFRLVSFLEAKAENLHRGAHHYTGLLKLQERVLNNVVIHLLGDEDPRVRHVAAASLIR............................................................................................................................................................................................................................................................................................................................................................................................................... 929
4 -8.9204u7a_A mol:protein length:826 Ribosome biogenesis protein ERB1  ali model follow..  11  1..................................................................ASAALEVLFQGP---------GMMAKNNKTTEAKMSKKRAASEESDVEEDEDKLLSVDGLIDAEASESDEDDDEYESAVEEKESSSDKEAQDDSDDDSDAELNKLLAEEEGDGEEDYDSSEFSDDTTSLTDRLSGVKLQTIVDPNIYSKYADGSDRIIKPEINPVYDSDDSDAETQNT-------------------------------------------------------------------------------NIPLS----DEMPH-IGYDINGKRIMR-----AKGSALDQLLDSIELPEGWTGLLDKNSGSSLNLTKEELELISKIQRNEQTDDSINPYEPLIDWFTRHEEVMPLTAVPEPKRRFVPSKNEAKRKIVRAIREGRIIPPKKLKEMKEKEKIE....................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 317
5 -8.5005xjc_x mol:protein length:703 Protein CASC3  ali model follow..  5  3.............................................................DRRRQRASQDTEDEESG------ASGSDSGGSPLRGGGSCSGSAGGGGSGSLPSQRGGRTGALHLRRVESGGAKSAEESECESEDGIEGDAVLSDYESAEDSEGEEGEYSEEENSKVELKSEANDAVNSSTKEEKGEEKPDTKSTVTGERQSGDGQESTEPVENKVGKKGPKHLDDDEDRKN----------------------------------------------------------------------------------PIPRKQEEEVRPKGRQRKLWKDEGRWE---QAPKSRQELIYDIRSAH............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 248
6 -7.7505oql_c mol:protein length:785 Putative U3 small nucleolar ribonucleoprotein protein  ali model follow..  11  163..KVNGEVEEEEGEDKVIEFGEDGFEVGSSDEEESEEEGNEEADTEDSDGEGASLGDENAMFDLEAEEDSGSEEDKSDVGEEVDGEVDGEKHSDLDGEEEGEEGEEDEEDEEDDDESAEDLVEDPHGLNDGFFSIDEFNKQTQMWEDQDMRAEPTAELDDDSEDIDWHADPFAVKPSKRGKKDDGDMDLDDEEDESDDEAPPVGKKALEKMLDKDEDDEGGNLEDDLADGMGMDLTANDIYYKDFFAPPRKKKKPGSSKKKRELELETKRPDDADVERAEQDVRRDLFDDLSEHEDSEDALSDASAGDPKSRKSAHERRQAKIAEQIRKLEAELVAKR-----------AWTEATAADRPVNSL--------------------------LGEDME----------------DHVGKPVPVVTEEVSESIEELIKRR---------------ILAGEFDEVLRRRPDMFGNPH--------VRRGLVDVEDTKAKQSLAEIYEEEAVKKANPDAYVSAADEKLRRDEEEIKR............................................................................................................................................................................................................................................................................................................................................................................................................. 621
7 -7.6205gjv_A mol:protein length:1873 Voltage-dependent L-type calcium channel subunit alpha-1S  ali model follow..  9 1373...........................................................................................................................................................................................................................................................................................................................................................INLFVAVIMDN-------FDYLTRDWSILGPHHLDEFKAIWAEYDPEAKGRIKHLDVVT-QPPLGFGKFCPHRVACKRLVGMNMPLNSDGTVTFNATLFALVRTALKIKTEGNFEQANEELRAIIKKIWKRTSMKLLDQVIPPIGDDEVTV-----GKFYATFL------------IQEHFRKFMKRQEEYYGYRPKKDTVQIQAGLRTIEEEAAPEIRRTISGDLTAEEELERAMVEAAMEERIFRRTGGLFGQVDTFLERTNSLPPVMANQRPLQFAEIEMEELESPVFLEDFPQDARTNPLARANTNNANANVAYGNSNHSNNQMFSSVHCEREFPGEAETPAAGRGALSHSHRALGPHSKPCAGKLNGQLVQPGMPINQAPPAPCQQPSTDPPERGQRRTSLTGSLQDEAPQRRSSEGSTPRRPAPATALLIQEALVRGTLAADA---GFVTATSQALADACQMEPE---------------------------------EVEVAATELLKARESVQGMAS----------PGSLSRRSSLGSLDQVQGSQETLIP--PRP................. 1873
8 -7.5703j7y_3 mol:protein length:188 bL35  ali model follow..  17  98...............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................SARKGKRKTVKAVIDR-------HCGLW----VRRKAGYKKKLWKKT---PARKKRLREFVFCNKTQSKLLDKWYVDD-PYKYHDRTNLK........................................ 187
9 -7.3504ce4_8 mol:protein length:188 MRPL35  ali model follow..  17  100.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................RKGKRKTVKAVIYR-------HSGLW----LRRKAGYKKKLWKKTAARKRR----REFVFCNKTQSKLLDKWYADD-PYKYQDRTNLK........................................ 187
10 -7.1905dud_B mol:protein length:218 YbgJ  ali model follow..  14  65...........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................LDAIERLQRWWEESEALEPESRFIEIP-YGGAGGPDLAVVAAHCGLSEKQ---------------VVELHSSVEYVVWFLGFQPFPYLG--SLPEQLHTP------------RRAEPRLLVPAGSVVYPLATPG 179
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 3 4 1   jobs submitted since Jan 1, 2011
Comments and questions to: webmaster
Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Jaroszewski L, Slabinski L, Wooley J, Deacon AM, Lesley SA, Wilson IA, Godzik A. Genome pool strategy for structural coverage of protein families. Structure. 2008 Nov 12;16(11):1659-67.