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Query: [I] KOG1683 Hydroxyacyl-CoA dehydrogenase/enoyl-CoA hydratase, from COG1018

Results of FFAS03 search in PDB1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MLSRVVHRSSSVFRTNLSFRLFSQSAFAVHSTHRVEKQGDVAVMKIDLPNTTENVLNKALFAEMNETLDRLQSDQSVKAIVVMSGKPNSFVAGADIQMFKAEKTAAGVSNLLREGQKQLLTIELSQKPIVAAIMGSCMGGGLEIALACHYRIAVNDKKTLLGLPEVTLGIMPGDGGTQRLPKLTTVQNVLDLTLTGKRIKANKAMKIGIVDRVIQPLGDGICTSTETTHKYLEEIAVQSARELANGKLKINRDKGFVHNATQAVMTSKFVLDNVILKMAKNKLIKLTNGNYPAPLKILDVVRTAYLDPKNGYEAEAKAFGELSQTFQSKALFGLFEGSTNAKKNKYGKGLPVNEIAVVGAGFMGAGIANVTINKGIRTVLLDANQAGVERGQNHVATHLNRQLKRQKISKLEREKIYNHLVPTIDYSAMKNADVVIEAVFEDLPLKHKVIRQIENVVGPNTIIASNTSALPIKDIAAASSRSDKVIGMHYFSPVEKMQLLEIITHDGTSKETLATAAQLGLKQGKLVVVVKDCPGFFVVRCLSPMMSEIVRLLQEGVEPSELDKLTTKFGFPVGAATLADEAGLDVAEHVARYLGTALGPRVHGGSVDLLSELVRAGHKGRKTSKGIFVYGDGAKGSKKVNQEAAKLFEKYKLTPIKSVSSPEDRQLRLVSRFVNEALLCLEEGVISSPSDGDIASVFGLGFPPFWGGPFRFVDLYGAGKLVAAMDRFAGVYESVQFEPCQLLRNHAKSGGQFYSLast
1 -172.0005zqz_A mol:protein length:763 Trifunctional enzyme subunit alpha, mitochondrial  ali model follow..  49  9ILSRFSAFRILRSRGYICRNFTGSSALLTRTHINYGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIAGADINMLAACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQLVEPLGPGLKPPEERTIEYLEEVAITFAKGLADKKISPKRDKGLVEKLT-AYAMTIPFVRQQVYKKVEEKVRKQTKGLYPAPLKIIDVVKTGEQGSDAGYLCESQKFGELVMTKESKALMGLYHGQVLCKKNKGAPQKDVKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTSFERDSIFSNLTGQLDYQGFEKADMVIEAVFEDLSLKHRVLKEVEAVIPDHCIFASNTSALPISEIAAVSKRPEKVIGMHYFSPVDKMQLLEIITTEKTSKDTSASAVAVGLKQGKVIIVVKDGPGFYTTRCLAPMMSEVIRILQEGVDPKKLDSLTTSFGFPVGAATLVDEVGVDVAKHVAEDLGKVFGERFGGGNPELLTQMVSKGFLGRKSGKGFYIYQEGVKRK-DLNSDMDSILASLKLPPKSEVSSDEDIQFRLVTRFVNEAVMCLQEGILATPAEGDIGAVFGLGFPPCLGGPFRFVDLYGAQKIVDRLKKYEAAYGK-QFTPCQLLADHANSNKKFYQ 763
2 -165.0001wdk_A mol:protein length:715 Fatty oxidation complex alpha subunit  ali model follow..  31  14.....................................ESGIVELKFDLKGESVNKFNRLTLNELRQAVDAIKADASVKGVIVSSGK-DVFIVGADITEFVENFKLPELIAGNLEANKIFSDFEDLNVPTVAAINGIALGGGLEMCLAADFRVMA--DSAKIGLPEVKLGIYPGFGGTVRLPRLIGVDNAVEWIASGKENRAEDALKVSAVDAVVTADKLG-------------AAALDLIKRAISGELDYKAK----RQPKLEKLKLNAIEQMMAFETAKGFVAGQAGPNYPAPVEAIKTIQKANFGRDKALEVEAAGFAKLAKTSASNCLIGLFLNDQELKKVYDKIAKDVKQAAVLGAGIMGGGIAYQSASKGTPILMKDINEHGIEQGLAEAAKLLVGRVDKGRMTPAKMAEVLNGIRPTLSYGDFGNVDLVVEAVVENPKVKQAVLAEVENHVREDAILASNTSTISISLLAKALKRPENFVGMHFFNPVHMMPLVEVIRGEKSSDLAVATTVAYAKKMGKNPIVVNDCPGFLVNRVLFPYFGGFAKLVSAGVDFVRIDKVMEKFGWPMGPAYLMDVVGIDTGHHGRDVMAEGFPDRMKDDRRSAIDALYEAKRLGQKNGKGFYAYEADKKGKQKKLVDSSVLEVLKPIVYEQRDVTDEDIINWMMIPLCLETVRCLEDGIVETAAEADMGLVYGIGFPLFRGGALRYIDSIGVAEFVALADQYAEL--GALYHPTAKLREMAKNGQSFFG 715
3 -159.0004b3h_A mol:protein length:736 FATTY ACID BETA-OXIDATION COMPLEX ALPHA-CHAIN FADB  ali model follow..  30  2..................GSSSQDPNSMPDNTIQWDKADGIVTLTMDDPSGSTNVMNEAYIESMGKAVDRLVAEKDSITGVVVASAKKTFFAGGDVKTMIQAEDAGDVFNTVETIKRQLRTLETLGKPVVAAINGAALGGGLEIALACHHRIAADVKGSQLGLPEVTLGLLPGGGGVTRTVRMFGIQNAVSVLAQGTRFKPAKAKEIGLVDELVATVE------------ELVPAAKAWIKEELKANPDGAGQPWDKKGYKMPGGTPSSPGLAAILPSFPSNLRKQLKGPMPAPRAILAAAVEGQVDFDTASRIESRYFASLVTGQVAKNMMQAFFFDLQAINPEGIGKTPIKRIGVLGAGMMGAGIAYVSAKAGYEVVLKDVSLEAAAKGKGYSEKLEAKALERGRTTQERSDALLARITPTADAADFKGVDFVIEAVFENQELKHKVFGEIEDIVEPNAILGSNTSTLPITGLATGVKRQEDFIGIHFFSPVDKMPLVEIIKGEKTSDEALARVFDYTLAIGKTPIVVNDSRGFFTSRVIGTFVNEALAMLGEGVEPASIEQAGSQAGYPAPPLQLSDELNLELMHKIAVATRKGVEDAGGTPAEAVVEKMIELGRSGRLKGAGFYEYADGKRSGLWPGLRETF-------KSGSSQPPLQDMIDRMLFAEALETQKCLDEGVLTSTADANIGSIMGIGFPPWTGGSAQFPAGTGKAAFVARARELAAAYGD-RFLPPESLLS.......... 730
4 -158.0002wtb_A mol:protein length:725 FATTY ACID MULTIFUNCTIONAL PROTEIN (ATMFP2)  ali model follow..  28  2.........................DSRTKGKTVMEVGDGVAVITLINP--PVNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAK-GRFSGGFDISGFGEMQKGNEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHARISA--PAAQLGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAVVPPAELV-------------TTARRWALDIVGRRKPWVSSVSKTDKL-------PPLGEAREILTFAKAQTLKRAPNMKHPLMCLDAIEVGVSGPRAGLEKEAEVASQVVKLDTTKGLIHVFFSQRGTAKDRGLVPRKIKKVAIIGGGLMGSGIATALILSNYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQEKFEKTMSLLKGSLDYESFRDVDMVIEAVIENISLKQQIFADLEKYCPQHCILASNTSTIDLNKIGERTKSQDRIVGAHFFSPAHIMPLLEIVRTNHTSAQVIVDLLDVGKKIKKTPVVVGNCTGFAVNRMFFPYTQAAMFLVECGADPYLIDRAISKFGMPMGPFRLCDLVGFGVAIATATQFIENFSERT--YKSMIIPLMQEDKRAGEATRKGFYLYDDKRKAKPKKYIEKARSISGVKLDPKLANLSEKDIIEMTFFPVVNEACRVFAEGIAVKAADLDIAGIMGMGFPPYRGGIMFWADSIGSKYIYSRLDEWSKAYGE-FFKPCAFLAERGSKGVLLSA 716
5 -157.0003zw8_A mol:protein length:742 PEROXISOMAL BIFUNCTIONAL ENZYME  ali model follow..  29  1................MGSSSSGLVPRGSHMAEYLRLPHSLAMIRLCNP--PVNAVSPTVIREVRNGLQKAGSDHTVKAIVI-CGANGNFCAGADIHGFSAFTPGLAL-------GSLVDEIQRYQKPVLAAIQGVALGGGLELALGCHYRIA--NAKARVGLPEVTLGILPGARGTQLLPRVVGVPVALDLITSGKYLSADEALRLGILDAVVKSD--------------PVEEAIKFAQKIIDKPIEPRRIFNKPVP--------SLPNMDSVFAEAIAKVRKQYPG-VLAPETCVRSIQASKHPYEVGIKEEEKLFMYLRASGQAKALQYAFFAEKSANKWKTASAQPVSSVGVLGLGTMGRGIAISFARVGISVVAVESDPKQLDAAKKIITFTLEKEASRAHQNGQASA--KPKLRFSSSTKELSTVDLVVEAVFEDMNLKKKVFAELSALCKPGAFLCTNTSALNVDDIASSTDRPQLVIGTHFFSPAHVMRLLEVIPSRYSSPTTIATVMSLSKKIGKIGVVVGNCYGFVGNRMLAPYYNQGFFLLEEGSKPEDVDGVLEEFGFKMGPFRVSDLAGLDVGWKIRKGQGLTGPSLPNSRYSPLGDMLCEAGRFGQKTGKGWYQYDKPLGRIPDPWLSTFLSQYREVHHIEQRTISKEEILERCLYSLINEAFRILEEGMAARPEHIDVIYLHGYGWPRHKGGPMFYAASVGLPTVLEKLQKYYRQNPDPQLEPSDYLRRLVAQGSPPLK 723
6 -97.6003k6j_A mol:protein length:460 Protein F01G10.3, confirmed by transcript evidence  ali model follow..  27  2............................................................................................................................................................................................................................................................................................................................GSTGENLYFQGSEVRSYLMEAHSLAGQHTNSEAYDVNSVAIIGGGTMGKAMAICFGLAGIETFLVVRNEQRCKQELEVM---YAREKSFKRLNDKRIEKINANLKITSDFHKLSNCDLIVESVIEDMKLKKELFANLENICKSTCIFGTNTSSLDLNEISSVLRDPSNLVGIHFFNPANVIRLVEIIYGSHTSSQAIATAFQACESIKKLPVLVGNCKSFVFNRLLHVYFDQSQKLMYEGYLPHQIDKIITNFGFLMGPMTVADMNGFDVMEKLKK--------ENGLEPNPIEKEMWRLKRYGRKTNKGFYKYDDKTQRKNDTEMEQIIRRVSQNAKSNIQIINDQDVINFMLYPTVNEGYRCIEEGVISNESLIDIMFILGFGWPIHSGGPMRFGKTEGLDKIANMLVHWSSLEPESAYIVADALKTANVSTGSS.. 439
7 -78.2003mog_A mol:protein length:483 Probable 3-hydroxybutyryl-CoA dehydrogenase  ali model follow..  29  2............................................................................................................................................................................................................................................................................................................................................................SLNVQTVAVIGSGTMGAGIAEVAASHGHQVLLYDISAEALTRAIDGIHARLNSRVTRGKLTAETCERTLKRLIPVTDIHALAAADLVIEAASERLEVKKALFAQLAEVCPPQTLLTTNTSSISITAIAAEIKNPERVAGLHFFNPAPVMKLVEVVSGLATAAEVVEQLCELTLSWGKQPVRCHSTPGFIVNRVARPYYSEAWRALEEQAAPEVIDAALRGAGFPMGPLELTDLIGQDVNFAVTCSVFNAFWQERRFLPSLVQQELVIGGRLGKKSGLGVYDWRAERVNPDSATRKAIYYLQQQGKTVLQIADYPGMLIWRTVAMIINEALDALQKGVA-SEQDIDTAMRLGVNYPY---GPLAWGAQLGWQRILRLLENLQHHYGEERYRPCSLLRQRALLESGYES 475
8 -77.4004kug_A mol:protein length:290 3-hydroxybutyryl-CoA dehydrogenase  ali model follow..  34  1...............................................................................................................................................................................................................................................................................................................................................................MKKVFVLGAGTMGAGIVQAFAAKGCEVIVRDIKEEFVDRGIATITKSLSKLVAKEKITEADKEEILSRISGTTDMKLAADCDLVVEAAIENMKIKKEIFAELDGICKPETILASNTSSLSITEVASATKRADKVIGMHFFNPAPVMKLVEVIRGAATSQETFDAVKEMSESIGKTPVEVAEAPGFVVNRILIPMINEATFILQEGAKEEDIDAAMKGANHPMGPLALGDLIGLDVCLAIMDVLYNETGDT-KYRASSLLRKYVRAGWLGRKTGKGFYDYSKSK......................................................................................................................... 284
9 -77.0004pzc_A mol:protein length:284 3-Hydroxyacyl-CoA dehydrogenase  ali model follow..  38  2..............................................................................................................................................................................................................................................................................................................................................................SIRTVGIVGAGTMGNGIAQACAVVGLNVVMVDISDAAVQKGVATVASSLDRLIKKEKLTEADKASALARIKGSTSYDDLKATDIVIEAATENYDLKVKILKQIDGIVGENVIIASNTSSISITKLAAVTSRADRFIGMHFFNPVPVMALVELIRGLQTSDTTHAAVEALSKQLGKYPITVKNSPGFVVNRILCPMINEAFCVLGEGASPEEIDEGMKGCNHPIGPLALADMIGLDTMLAVMEVLYTEFADP-KYRPAMLMREMVAAGYLGRKTGRGVYVYSK........................................................................................................................... 284
10 -75.5003rqs_A mol:protein length:324 Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial  ali model follow..  29  2..........................................................................................................................................................................................................................................................................................................................................GSHMAFVTRQFMRSASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKKAGDEFVEKTLSTIATSTDAASVHSTDLVVEAIVENLKVKNELFKRLDKFAAEHTIFASNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMTSQKTFESLVDFSKALGKHPVSCKDTPGFIVNRLLVPYLMEAIRLYERGASKEDIDTAMKGAGYPMGPFELLDYVGLDTTKFIVDGWHEMDAENPLHQPSPSLNKLVAENKFGKKTGEGFYKYK............................................................................................................................ 318
11 -75.5006HRD Entity 1(prereleased)  ali follow..  29  1...............................................................................................................................................................................................................................................................................................................................................MGSSSSGLVPSHMSDAIQRVGVVGAGQMGSGIAEVSARAGVEVTVFEPAEALITAGRNRIVKSLERAVSAGKVTERERDRALGLLTFTTDLNDLSDRQLVIEAVVEDEAVKSEIFAELDRVVTPDAVLASNTSSIPIMKVAAATKQPQRVLGLHFFNPVPVLPLVELVRTLVTDEAAAARTEEFASTLGKQVVRCSDRSGFVVNALLVPYLLSAIRMVEAGATVEDVDKAVVGLSHPMGPLRLSDLVGLDTLKLIADKMFEEFKEP-HYGPPPLLLRMVEAGQLGKKSGRGFYTYAAALE........................................................................................................................ 305
12 -75.1001f12_A mol:protein length:310 L-3-HYDROXYACYL-COA DEHYDROGENASE  ali model follow..  30  1.................................................................................................................................................................................................................................................................................................................................................SSSSTASASAKKIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKKAGDECVEKTLSTIATSTDAASVHSTDLVVEAIVENLKVKNELFKRLDKFAAEHTIFASNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMTSQKTFESLVDFSKALGKHPVSCKDTPGFIVNRLLVPYLMEAIRLYERGASKEDIDTAMKGAGYPMGPFELLDYVGLDTTKFIVDGWHEMDAENPLHQPSPSLNKLVAENKFGKKTGEGFYKYKLE.......................................................................................................................... 304
13 -75.1002hdh_A mol:protein length:293 L-3-HYDROXYACYL COA DEHYDROGENASE  ali model follow..  30  1............................................................................................................................................................................................................................................................................................................................................................KIIVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKKAGDEFVAKTLSTIATSTDAASVHSTDLVVEAIVENLKVKNELFKRLDKRAAEHTIFASNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMTSQKTFESLVDFSKALGKHPVSCKDTPGFIVNRLLVPYLMEAIRLYERGASKEDIDTAMKGAGYPMGPFELLDYVGLDTTKFIVDGWHEMDAENPLHQPSPSLNKLVAENKFGKKTGEGFYKYKAA.......................................................................................................................... 293
14 -75.0003hdh_A mol:protein length:302 PROTEIN (L-3-HYDROXYACYL COA DEHYDROGENASE)  ali model follow..  29  1.................................................................................................................................................................................................................................................................................................................................................SSSSTAAASAKKILVKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKKAGDEFVEKTLSSISTSTDAASVHSTDLVVEAIVENLKVKSELFKRLDKFAAEHTIFASNTSSLQITSLANATTRQDRFAGLHFFNPVPLMKLVEVVKTPMTSQKTLESLVDFSKTLGKHPVSCKDTPGFIVNRLLVPYLIEAVRLYERGASKEDIDTAMKGAGYPMGPFELLDYVGLDTTKFIIDGWHEMDSQNPLFQPSPAMNKLVAENKFGKKTGEGFYKYK............................................................................................................................ 302
15 -74.6004j0e_A mol:protein length:320 Probable 3-hydroxyacyl-CoA dehydrogenase F54C8.1  ali model follow..  30  2...................................................................................................................................................................................................................................................................................................................................................GSMFTAKCAMQNIRNVAIVGSGQMGSGIAQVTASSGFNVMLADVNKKALDRAMKAISQSVTHLSKKQKGTDKEKTLTMSRIKTCNNVSTVADADLIIEAAIENIDLKRGIFAQIEQSCKKDSILTTNTSSFLLEDVAKGLQDKTRFGGLHFFNPVPVMKLLEVIRSDDTSDETYATLIKFGTAVGKTTVACKDSPGFIVNRLLIPYFFEAARMYERGASMTDIDEAMKGAGHPMGPFELADYIGLDTVKFVMDGWAAKYPEVQLFEASPLVDKLVAEGKLGRKTGDGFYSYKKEFGTSSTGSSGSSLEV........................................................................................................... 317
16 -70.2004dyd_A mol:protein length:283 Diketoreductase  ali model follow..  23  2.............................................................................................................................................................................................................................................................................................................................................................TGITNVTVLGTGVLGSQIAFQTAFHGFAVTAYDINTDALDAAKKRFEGLAAVYEKEAGAADGAAQKALGGIRYSDDLAQVKDADLVIEAVPESLDLKRDIYTKLGELAPAKTIFATNSSTLLPSDLVGYTGRGDKFLALHFANHVWVNNTAEVMGTTKTDPEVYQQVVEFASAIGMVPIELKEKAGYVLNSLLVPLLDAAAELLVDGADPETIDKTWRGTGAPKGPFEIFDIVGLTTAYNISSVSG----PKQREFAAYLKENYIDKGKLGLATGEGFYRY............................................................................................................................. 283
17 -67.6001zej_A mol:protein length:293 3-hydroxyacyl-CoA dehydrogenase  ali model follow..  29  1..........................................................................................................................................................................................................................................................................................................................................................MGSDKIMKVFVIGAGLMGRGIAIAIA-SKHEVVLQDVSEKALEAAREQIP-----------------EELLSKIEFTTTLEKVKDCDIVMEAVFEDLNTKVEVLREVERLT--NAPLCSNTSVISVDDIAERLDSPSRFLGVHWMNPPHVMPLVEIVISRFTDSKTVAFVEGFLRELGKEVVVCKG--QSLVNRFNAAVLSEASRMIEEGVRAEDVDRVWKHLGLLFGPLGNLDYIGLDVAYYASLYLYKRFGDE-KFKPPEWLQEKIKKGEVGVKAGKGIYEYGPKAYEERVERLKKLLRFLGLE....................................................................................................... 287
18 -65.6004om8_A mol:protein length:309 3-hydroxybutyryl-coA dehydrogenase  ali model follow..  30  2...............................................................................................................................................................................................................................................................................................................................................................IRNIAIIGLGTMGPGMAARLARGGLQVVAYDVAPAAIERARSMLSVAETVLDALGIALP---SAGVGTVRFTDDIGDVSGADLVIENVPENISIKADVYRTIDGLIGQDTIVASDTSGIPITKLQAHISYPERMVGMHWSNPPHIIPMIEVIAGEKTAPQTVATIRDLIRSIGLLPVVVKDVPGFVENRVLYALLREAVDLVERGIDPEDLDTCVSGIGYKIGPMALLDMAGLDIYKSVSSFLNADLSNRDD--VAPMVLEKTSASKFGIKSGEGMFCYTPEQTKA...................................................................................................................... 289
19 -58.7003f3s_A mol:protein length:313 Lambda-crystallin homolog  ali model follow..  20  1.............................................................................................................................................................................................................................................................................................................................................................SMAGCVVIVGSGVIGRSWAMLFASGGFQVKLYDIEQQQIRNALENIRKEMKLLEQAGSLKGSSVEEQLSLISGCPNIQEVEGAMHIQECVPEDLELKKKIFAQLDSIIDDRVILSSSTSCLMPSKLFAGLVHVKQCIVAHPVNPPYYIPLVELVPHPETAPTTVDRTHALMKKIGQCPMRVKEVAGFVLNRLQYAIISEAWRLVEEGVSPSDLDLVMSGLGMRIGPLETMHLNAEGMLSYCDRYSEGIKHVLQTFGPIPEFSRATAEKDMCMKVPDDPEHLAARRQWRDE.................................................................................................................... 301
20 -58.5003ado_A mol:protein length:319 Lambda-crystallin  ali model follow..  19  1..........................................................................................................................................................................................................................................................................................................................................................MASPAAGDVLIVGSGLVGRSWAMLFASGGFRVKLYDIEPRQITGALENIRKEMKSLQQSGSLKGSSAEEQLSLISSCTNLAEVEGVVHIQECVPENLDLKRKIFAQLDSIVDDRVVLSSSSSCLLPSKLFTGLAHVKQCIVAHPVNPPYYIPLVELVPHPETSPATVDRTHALMRKIGQSPVRVKEIDGFVLNRLQYAIISEAWRLVEEGVSPSDLDLVMSGLGMRIGPLETMHLNAEGMLSYCDRYSEGMKR-KSFGSIPEFSGATVEKVNQAMCKKVPADPEHLAARREWRDECLKRLAKLKRQ....................................................................................................... 315
21 -51.9003pea_A mol:protein length:261 Enoyl-CoA hydratase/isomerase family protein  ali model follow..  28  1.........................SNAMLKFLSVRVEDHIAVATLNHA--PANAMSSQVMHDVTELIDQVEKDDNIRVVVIH-GEGRFFSAGADIKEFTSVTEAKQATELAQLGQVTFERVEKCSKPVIAAIHGAALGGGLEFAMSCHMRFATES--AKLGLPELTLGLIPGFAGTQRLPRYVGKAKACEMMLTSTPITGAEALKWGLVNGVFAEETFL-------------DDTLKVAKQIAGKSPATARAVLEL------------------------------------------LQTTKSSHYYEGVQREAQIFGEVFTSEDGREGVAAFLEKRK............................................................................................................................................................................................................................................................................................................................................................................................................................... 255
22 -51.3001sg4_A mol:protein length:260 3,2-trans-enoyl-CoA isomerase, mitochondrial  ali model follow..  21  5..............................VLVEPDAGAGVAVMKFKNP--PVNSLSLEFLTELVISLEKLENDKSFRGVILTSDRPGVFSAGLDLTEMCG-RSPAHYAGYWKAVQELWLRLYQSNLVLVSAINGACPAGGCLVALTCDYRILADNPRYCIGLNETQLGIIAPFWLKDTLENTIGHRAAERALQLGLLFPPAEALQVGIVDQVVPEEQVQSTALSAIAQMAIPDHARQLTKAMMR--------------------------------------------------------KATASRLVTQRDADVQNFVSFISKDSIQKSLQMYLERLKEEK............................................................................................................................................................................................................................................................................................................................................................................................................................ 259
23 -51.1002ppy_A mol:protein length:265 Enoyl-CoA hydratase  ali model follow..  27  2.......................TAVETKKQYLTVFKEDGIAEIHLHIN--KSNSYDLEFYKEFNAAIDDIRFDPDIKVVIVMSDVPKFFSAGADINFLRSA-DPRFKTQFCLFCNETLDKIARSPQVYIACLEGHTVGGGLEMALACDLRFMGDE-AGKIGLPEVSLGVLAGTGGTQRLARLIGYSRALDMNITGETITPQEALEIGLVNRVFPQAETR-------------ERTREYARKLANSATYAVSNIKL------------------------------------------AIMNGKEMPLNVAIRYEGELQNLLFRSEDAKEGLSAFLEKRQ............................................................................................................................................................................................................................................................................................................................................................................................................................... 259
24 -50.7005wyb_B mol:protein length:280 Probable enoyl-CoA hydratase/isomerase  ali model follow..  26  2...............NTAVEPYKASSFDDTHKLTVEKHGHTALITINHP--PANTWDRDSLIGLRQLIEHLNRDDDIYALVVTGQGPKFFSAGADLNMFADG-DKARAREMARRFGEAFEALRDFRGVSIAAINGYAMGGGLECALACDIRIAERQ--AQMALPEAAVGLLPCAGGTQALPWLVGEGWAKRMILCNERVDAETALRIGLVEQVVDSGEARGAALLLAAKARQSPVAIRTIKPLIQ--------------------------------------------------------GARERAPNTWLPEERERFVDLFDAQDTREGVNAFLEKRD............................................................................................................................................................................................................................................................................................................................................................................................................................... 266
25 -50.5005z7r_A mol:protein length:267 Short-chain-enoyl-CoA hydratase  ali model follow..  32  1...........................MELNNVILEKEGKVAVVTINRP-KALNALNSDTLKEMDYVIGEIENDSEVLAVILTGAGEKSFVAGADISEMKEM-NTIEGRKFGILGNKVFRRLELLEKPVIAAVNGFALGGGCEIAMSCDIRIASSN--ARFGQPEVGLGITPGFGGTQRLSRLVGMGMAKQLIFTAQNIKADEALRIGLVNKVVEPSELMNTAKEIANKVSNAPVAVKLSKQAIN--------------------------------------------------------RGMQCDIDTALAFESEAFGECFSTEDQKDAMTAFIEKRKIE............................................................................................................................................................................................................................................................................................................................................................................................................................. 256
26 -50.5005jbx_A mol:protein length:261 3-hydroxybutyryl-CoA dehydratase  ali model follow..  29  5..............................PEFKVDARGPIEIWTIDGE-SRRNAISRAMLKELGELVTRVSSSRDVRAVVITGAGDKAFCAGADLKERATM-AEDEVRAFLDGLRRTFRAIEKSDCVFIAAINGAALGGGTELALACDLRVAAPA--AELGLTEVKLGIIPGGGGTQRLARLVGPGRAKDLILTARRINAAEAFSVGLANRLAPEGHLLAVAYGLAESVENAPIAVATAKHAID--------------------------------------------------------EGTGLELDDALALELRKYEEILKTEDRLEGLRAFAEKRA............................................................................................................................................................................................................................................................................................................................................................................................................................... 255
27 -50.4001xx4_A mol:protein length:261 3,2-trans-enoyl-CoA isomerase, mitochondrial  ali model follow..  21  8................................VEKEGEAGIAVMKFKNP--PVNSLSLEFLTEFVISLEKLENDKSIRGVILTSERPGIFSAGLDLMEMYG-RNPAHYAEYWKAVQELWLRLYLSNLTLISAINGASPAGGCLMALTCDYRIMADNSKYTIGLNESLLGIVAPFWLKDNYVNTIGHRAAERALQLGTLFPPAEALKVGLVDEVVPEDQVHSKARSVMAKFTIPDHSRQLTKSMMR--------------------------------------------------------KATADNLIKQREADIQNFTSFISRDSIQKSLHVYLEKLKQKK............................................................................................................................................................................................................................................................................................................................................................................................................................ 260
28 -50.4001hzd_A mol:protein length:272 AU-BINDING PROTEIN/ENOYL-COA HYDRATASE  ali model follow..  25  4......................MKTEDELRVRHLEEENRGIVVLGINRA-YGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGIFCAGADLKERAKM-SSSEVGPFVSKIRAVINDIANLPVPTIAAIDGLALGGGLELALACDIRVAASS--AKMGLVETKLAIIPGGGGTQRLPRAIGMSLAKELIFSARVLDGKEAKAVGLISHVLEQNQ---------EGDAAYRKALDLAREFLPQGPVAMRVAKL------------------------------------------AINQGMEVDLVTGLAIEEACYAQTIPTKDRLEGLLAFKEKRP............................................................................................................................................................................................................................................................................................................................................................................................................................... 266
29 -50.4004di1_A mol:protein length:277 Enoyl-CoA hydratase EchA17  ali model follow..  21  2..............AMGTLEAQTQGPGSMNEFVSVVADQGLATLVVSRP--PTNAMTRQVYREIVAAADELGRRDDIGAVVLF-GGHEIFSAGDDMPELRTL-NAPEADTAARVRLEAIDAVAAIPKPTVAAVTGYALGAGLTLALAADWRVSGDN--VKFGATEILAGLIPGGGGMGRLTRVVGSSRAKELVFSGRFFDAEEALALGLIDDMVAPDDVYDSAVAWARRLECPPRALAAAKAVIN--------------------------------------------------------DVFELEATERAAAERRRYVELFAAGQRGPDGRGPGGGNT............................................................................................................................................................................................................................................................................................................................................................................................................................... 266
30 -49.8005zai_A mol:protein length:259 3-hydroxypropionyl-coenzyme A dehydratase  ali model follow..  32  1...........................MEFETIETKKEGNLFWITLNRP-DKLNALNAKLLEELDRAVSQAESDPEIRVIIIT-GKGKAFCAGADITQFNQL-TPAEAWKFSKKGREIMDKIEALSKPTIAMINGYALGGGLELALACDIRIAAEE--AQLGLPEINLGIYPGYGGTQRLTRVIGKGRALEMMMTGDRIPGKDAEKYGLVNRVVPLANLEQETRKLAEKAKKSPISLALIKEVVN--------------------------------------------------------RGLDSPLLSGLALESVGWGVVFSTEDKKEGVSAFLEKRE............................................................................................................................................................................................................................................................................................................................................................................................................................... 253
31 -49.7003kqf_A mol:protein length:265 Enoyl-CoA hydratase/isomerase family protein  ali model follow..  26  1......................SNAMLQLQNISVDYATPHVVKISLNRE-RQANSLSLALLEELQNILTQINEEANTRVVILTGAGEKAFCAGADLKERAGM-NEEQVRHAVSMIRTTMEMVEQLPQPVIAAINGIALGGGTELSLACDFRIAAES--ASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISAQEAKEYGLVEFVVPVHLLE-------------EKAIEIAEKIASNGPIAVRLAKE------------------------------------------AISNGIQVDLHTGLQMEKQAYEGVIHTKDRLEGLQAFKEKRT............................................................................................................................................................................................................................................................................................................................................................................................................................... 259
32 -49.2003h0u_A mol:protein length:289 Putative enoyl-CoA hydratase  ali model follow..  20  2........................SLTASYETIKARLDGTVLSATFNAP--PMNLIGPEVVRDLVALLEELAHPTAPRVVIFDSADADFFFPHVDMTKVPEAEAAKAGGPGDASLGMLFRKLSQLPAVTIAKLRGRARGAGSEFLLACDMRFASRE-NAILGQPEVGIGAPPGAGAIQHLTRLLGRGRALEAVLTSSDFDADLAERYGWVNRAVPDAE-------------LDEFVAGIAARMSGFPRD-------------------------------------------ALIAAKSAINAISLPAPAEVRADAALFQQLVRGEKVQQRTAELFKQGF............................................................................................................................................................................................................................................................................................................................................................................................................................... 260
33 -49.1004fzw_A mol:protein length:258 2,3-dehydroadipyl-CoA hydratase  ali model follow..  27  1..........................MRSMSELIVSRQQRVLLLTLNRP-AARNALNNALLMQLVNELEAAATDTSISVCVIT-GNARFFAAGADLNEMAEKDLAA---TLNDTRPQLWARLQAFNKPLIAAVNGYALGAGCELALLCDVVVAGEN--ARFGLPEITLGIMPGAGGTQRLIRSVGKSLASKMVLSGESITAQQAQQAGLVSDVFPSDLTLEYALQLASKARHSPLALQAAKQALR--------------------------------------------------------QSQEVALQAGLAQERQLFTLLAATEDRHEGISAFLQKRT............................................................................................................................................................................................................................................................................................................................................................................................................................... 252
34 -49.0002pbp_A mol:protein length:258 Enoyl-CoA hydratase subunit I  ali model follow..  27  1..........................MSEFVSIAARQEGAVGIIELARP-DVLNALSRQMVAEIVAAVEAFDRNEKVRVIVLT-GRGRAFAAGADIQEMAKDDPIR---LEWLNQFADWDRLSIVKTPMIAAVNGLALGGGFELALSCDLIVASSA--AEFGFPEVNLGVMPGAGGTQRLTKLIGPKRALEWLWTGARMSAKEAEQLGIVNRVVSPELLMEETMRLAGRAEQPPLALRLIKEAVQ--------------------------------------------------------KAVDYPLYEGMQFERKNFYLLFASEDQKEGMAAFLEKRK............................................................................................................................................................................................................................................................................................................................................................................................................................... 252
35 -48.9005xzd_A mol:protein length:258 Enoyl-CoA hydratase  ali model follow..  29  1...........................MAYETIIVEVEDHVALITLNRP-DALNALNDQLLSELVKALEDAQNNDKVRCIVIT-GSEKAFAAGADIKMMSEKSFVDVFA--GDLFGPEAEGIMRIRKPIIAAVSGYALGGGCELAMMCDFIICSDT--AKFGQPEINLGVIAGMGGSQRLTRFIGKSKSMDMNLTGRFMDAEEAERSGLVSRVVPAKKLMEETMTAAQKAEKSMIAVMAVKEAVN--------------------------------------------------------RSYEVPLREGLLFERRVFQSLFATEDQKEGMSAFAEKRE............................................................................................................................................................................................................................................................................................................................................................................................................................... 252
36 -48.9003h81_A mol:protein length:278 enoyl-CoA hydratase echA8  ali model follow..  26  11......................QGPGSMTYETILVERDQRVGIITLNRP-QALNALNSQVMNEVTSAATELDDDPDIGAIIIT-GSAKAFAAGADIKEMADLTFAD---AFTADFFATWGKLAAVRTPTIAAVAGYALGGGCELAMMCDVLIAADT--AKFGQPEIKLGVLPGMGGSQRLTRAIGKAKAMDLILTGRTMDAAEAERSGLVSRVVPADDLLTEARATATTSQMSASAARMAKEAVN--------------------------------------------------------RAFESSLSEGLLYERRLFHSAFATEDQSEGMAAFIEKRA............................................................................................................................................................................................................................................................................................................................................................................................................................... 266
37 -48.7003rsi_A mol:protein length:265 Putative enoyl-CoA hydratase/isomerase  ali model follow..  21  3........................GSMSAARELLVERDGPVVILTMNRP-HRRNALSTNMVSQFAAAWDEIDHDDGIRAAILT-GAGSAYCVGGDLSDGWMVRDGSAPPLDPATIGKGLLLSHTLTKPLIAAVNGACLGGGCEMLQQTDIRVSDEH--ATFGLPEVQRGLVPGAGSMVRLKRQIPYTKAMEMILTGEPLTAFEAYHFGLVGHVVPAGTAL-------------DKARSLADRIVRNGPLAVRNAKEA------------------------------------------IVRSGWLAEEDARAIEARLTRPVITSADAREGLAAFKEKRE............................................................................................................................................................................................................................................................................................................................................................................................................................... 259
38 -48.5003lao_A mol:protein length:258 enoyl-CoA hydratase/isomerase  ali model follow..  18  5.......................SEANSGPGRVTREQRGHLFLIGLDRAGK-RNAFDSAMLADLALAMGEYERSEESRCAVLF-AHGEHFTAGLDLMELAPKLAASGFRYPDGGVDPWGVVQPRRSKPLVVAVQGTCWTAGIELMLNADIAVAARG--TRFAHLEVLRGIPPLGGSTVRFPRAAGWTDAMRYILTGDEFDADEALRMRLLTEVVEPGEEL-------------ARALEYAERIARAAPLAVRAALQ------------------------------------------SAFQGRDEGDDAALSRVNESLAALIGSEDVREGVLAMV................................................................................................................................................................................................................................................................................................................................................................................................................................... 258
39 -48.2004olq_A mol:protein length:282 Enoyl-CoA hydratase/isomerase family protein  ali model follow..  21  2.............SSGVDLGTENLYFQSMTLPIRLDIAAPLAEIVLNKPER-RNALSVDMWAAIPGLVAEANANPDVKLILIHGGDAGAFAAGADISEFETIYATEDAKASGQRIAQALDAIENSEKPVIAAIEGACVGGGVSLAMAADLRVAGEG--AKFGVTPGKLGLVYPAGDTRRLLAAVGPGATKDILFTGRIFTAGEAKSLGLIDRLVEKGTAL-------------EAARVWAGEIAAISQ--------------------------------------------SVRATKRMIRGLQTGWTDETPEAQSLFLNGFANEDFKEGYRAFLDKRP............................................................................................................................................................................................................................................................................................................................................................................................................................... 270
40 -48.1004jwv_A mol:protein length:278 Short chain enoyl-CoA hydratase  ali model follow..  21  10......................ENLYFQSMADIDFRIEGHVAHVRLNRP-QGLNAITQEMDDLLLDAWTEVNANSDIWAVVLSAEGEKAFCIGADVSGGAERKTRMALGG---GLTGIGGPLVTCKKPMVAAVQGFCVGGGFELAMCADIIVAADT--AQFGLPETKVGIIGECGVVHRAMRQLPYHIALQLILTGERIKADEARHYGLVNEVVPFAELE-------------EAALRWASKLNAASPLAVQAAKAA------------------------------------------ALGRLGHPLEVALMTRFEPIEEYAATEDKKEGERAAGERRK............................................................................................................................................................................................................................................................................................................................................................................................................................... 266
41 -48.1003moy_A mol:protein length:263 Probable enoyl-CoA hydratase  ali model follow..  28  15...................................RPVAGVGLIRLDRP-DALNALNQTLEAEVLDAARDFDADLEIGAIVVT-GSERAFAAGADIAEMVTLTPHQ---ARERNLLSGWDSLTQVRKPIVAAVAGYALGGGCELAMLCDLVIAADT--ARFGQPEITLGILPGLGGTQRLTRAVGKAKAMDLCLTGRSLTAEEAERVGLVSRIVPAADLLDEALAVAQRARMSRPAGRAVKDAIN--------------------------------------------------------EAFERPLSAGMRYERDAFYAMFDTHDQTEGMTAFLEKRT............................................................................................................................................................................................................................................................................................................................................................................................................................... 257
42 -48.1001dub_A mol:protein length:261 2-ENOYL-COA HYDRATASE  ali model follow..  27  13...................................GKNSSVGLIQLNRP-KALNALCNGLIEELNQALETFEEDPAVGAIVLT-GGEKAFAAGADIKEMQNRTFQD---CYSGKFLSHWDHITRIKKPVIAAVNGYALGGGCELAMMCDIIYAGEK--AQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFPVETLVEEAIQCAEKANNSKIIVAMAKESVN--------------------------------------------------------AAFEMTLTEGNKLEKKLFYSTFATDDRREGMSAFVEKRK............................................................................................................................................................................................................................................................................................................................................................................................................................... 255
43 -48.0002a7k_A mol:protein length:250 CarB  ali model follow..  20  2................................VFEENSDEVRVITLDHPNK-HNPFSRTLETSVKDALARANADDSVRAVVVYGGAERSFSAGGDFNEVKQLSRSEDIEEWIDRVIDLYQAVLNVNKPTIAAVDGYAIGMGFQFALMFDQRLMAST--ANFVMPELKHGIGCSVGAA-ILGFTHGFSTMQEIIYQCQSLDAPRCVDYRLVNQVVESSALL-------------DAAITQAHVMASYPASAFINTKRA------------------------------------------VNKPFIHLLEQTRDASKAVHKAAFQARDAQGHFKNVLGKK................................................................................................................................................................................................................................................................................................................................................................................................................................ 249
44 -48.0004jyl_A mol:protein length:265 Enoyl-CoA hydratase  ali model follow..  26  19................................VEIERRGDASLIVLSRP-EKLNAINLEMLADLADQFSKAEKED---RVIVITGYGKNFSAGADINMLASF-DPASAYSFRLKMNSIAQRIRKSDKPVIALLKGYSMGGGLELAESADIRIAMSD--AVIGQPESSIGINAGAGGNVILPKLVGRGSAAYLAMSGKKLNAQEAMALGLVDEVVDDEAKAWKIIDDICKKP--KKTLQFIKRAIN--------------------------------------------------------SSYDMGLESAMDQEALYFSLLFTDPEVLDALSKWR................................................................................................................................................................................................................................................................................................................................................................................................................................... 258
45 -48.0002iex_A mol:protein length:272 Dihydroxynapthoic acid synthetase  ali model follow..  17  3.....................FEWVKQYDYEDIIYETYNGIAKITINRP-EVHNAFRPKTVNEMIDAFTKARDDSNIGVIILTGAGGKAFCSGGDQKVRGHGGYVGEDEIPRLNVLDLQRLIRVIPKPVIAMVAGYAIGGGHVLHVVCDLTIAADN--AIFGQTGPKVGSFDGGYGAGYLARIVGHKKAREIWYLCRQYTAQEALEMGLVNKVVPLEQ-------------LEEETVKWAQEILEKSP--------------------------------------------AIRFLKAAFNADSDGLAGIQQLAGDATLLFYTTEEAKEGMRAFKEKRK............................................................................................................................................................................................................................................................................................................................................................................................................................... 262
46 -47.8002uzf_A mol:protein length:273 NAPHTHOATE SYNTHASE  ali model follow..  17  5......................QWETLREYDEIKYEFYEGIAKVTINRP-EVRNAFTPKTVAEMIDAFSRARDDQNVSVIVLTGEGDLAFCSGGDQKKRGHGGYVGEDQIPRLNVLDLQRLIRIIPKPVIAMVKGYAVGGGNVLNVVCDLTIAADN--AIFGQTGPKVGSFDAGYGSGYLARIVGHKKAREIWYLCRQYNAQEALDMGLVNTVVPLEK-------------VEDETVQWCKEIMKHSP--------------------------------------------ALRFLKAAMNADTDGLAGLQQMAGDATLLYYTTDEAKEGRDAFKEKRD............................................................................................................................................................................................................................................................................................................................................................................................................................... 263
47 -47.8003hin_A mol:protein length:275 Putative 3-hydroxybutyryl-CoA dehydratase  ali model follow..  25  8......................QAATIADPSTLVVDTVGPVLTIGLNRP-KKRNALNDGLMAALKDCLTDI--PDQIRAVVIH-GIGDHFSAGLDLSELRE-RDATEGLVHSQTWHRVFDKIQYCRVPVIAALKGAVIGGGLELACAAHIRVAEAS--AYYALPEGSRGIFVGGGGSVRLPRLIGVARMADMMLTGRVYSAAEGVVHGFSQYLIENGSAY-------------DKALELGNRVAQNAPLTNFAVLQ------------------------------------------ALPMIAEANPQTGLLMESLMATVAQSDQEAKTRIRAFLDHKTAK............................................................................................................................................................................................................................................................................................................................................................................................................................. 265
48 -47.7003r0o_A mol:protein length:273 Carnitinyl-CoA dehydratase  ali model follow..  25  7......................ETLTEVTRQAAVVERRGNVALITIDRP-DARNAVNGAVSTAVGDALEEAQRDPEVWAVVITGAGDKSFCAGADLKAISRGENLYHAE--HPEWGFAGYVHHFIDKPTIAAVNGTALGGGSELALASDLVIACES--ASFGLPEVKRGLIAGAGGVFRIVEQLPRKVALELVLTGEPMTASDALRWGLINEVVPDGTVV-------------EAALALAERITCNAPLSVQA---------------------------------------SKRVAYGADDGIIGAEEPKWERTIREFTELLKSEDAKEGPLAFAEKRQ............................................................................................................................................................................................................................................................................................................................................................................................................................... 267
49 -47.6003gkb_A mol:protein length:287 Putative enoyl-CoA hydratase  ali model follow..  22  2.......................SLRNDAYSTLRVSSEHGVARIILDNP--PVNVIGATMMRELRTVLTTLADDSSVRVIVFSSADPEFFLAHVDMRIGEKMDALQELPADVNVFQAVGELIRHQPQVTIVKLAGKARGGGAEFVAAADMAFAAAE-TAGLGQIEALMGIIPGGGGTQYLRGRVGRNRALEVVLTADLFDAETAASYGWINRALPADELDEYVDRVARNAALPDGVIEAAKRSLPAD-----------------------------------------------------------DLKEGLLGENDAWAATFSLPAAQQLISGGLKDGA............................................................................................................................................................................................................................................................................................................................................................................................................................... 261
50 -47.6002hw5_A mol:protein length:286 Enoyl-CoA hydratase  ali model follow..  26  34.....................................NNTVGLIQLNRP-KALNALCDGLIDELNQALKIFEEDPAVGAIVLT-GGDKAFAAGADIKEMQNLSFQD---CYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGEK--AQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVETLVEEAIQCAEKASNSKIVVAMAKESVN--------------------------------------------------------AAFEMTLTEGSKLEKKLFYSTFATDDRKEGMTAFVEKRK............................................................................................................................................................................................................................................................................................................................................................................................................................... 274
51 -47.5003r9s_A mol:protein length:267 Carnitinyl-CoA dehydratase  ali model follow..  22  3........................GSMTDAPGALAERRGNVMVITINRP-EARNAVNAAVSIGVGDALEEAQHDPEVRAVVLTGAGDKSFCAGADLKAIARRENLYHPD--HPEWGFAGYVRHFIDKPTIAAVNGTALGGGTELALASDLVVADER--AQFGLPEVKRGLIAAAGGVFRIAEQLPRKVAMRLLLTGEPLSAAAARDWGLINEVVEAGSVLDAALAL----------------------------------------------------ASAITVNAPLSVQASKRIAYGVDDGVVVGDEPGWDRTMREMRALLKSEDAKEGPRAFAEKRE............................................................................................................................................................................................................................................................................................................................................................................................................................... 261
52 -47.5003swx_A mol:protein length:265 Probable enoyl-CoA hydratase/isomerase  ali model follow..  22  3........................GSMSDYETLRIRRDGYVLVIGLNRPAK-RNAFDKTMLEELALALGEYETDTDLRAAVLY-GEGPLFTAGLDLASVAAEIQGGASLTPEGGINPWQVDGRQLSKPLLVAVHGKVLTLGIELALAADIVIADET--ATFAQLEVNRGIYPFGGATIRFPRTAGWGNAMRWMLTADTFDAVEAHRIGIVQEIVPVGEHV-------------DTAIAIAQTIARQAP------------------------------------------LGVQATLRNARLAVREGDAAAEEQLVPTVRELFTSEDATLGVQAFLSRTT............................................................................................................................................................................................................................................................................................................................................................................................................................... 259
53 -47.4004jjt_A mol:protein length:252 Enoyl-CoA hydratase  ali model follow..  20  1........................SNAMTDDILLIDTDERVRTLTLNRPQS-RNALSAALRDRFFAALADAEADDDIDVVILT-GADPVFCAGLDLKELAG----------QTALPDISPRWPAMTKPVIGAINGAAVTGGLELALYCDILIASEH--ARFADTHARVGLLPTWGLSVRLPQKVGIGLARRMSLTGDYLSATDALRAGLVTEVVAHDQLL-------------PTARRVAASIVGNNQNAVRALLAS------------------------------------------YHRIDESQTAAGLWLEACAAKQFRTSGDTIAANREAVLQRGRAQ............................................................................................................................................................................................................................................................................................................................................................................................................................ 250
54 -47.3004wcz_A mol:protein length:272 Enoyl-CoA hydratase/isomerase  ali model follow..  26  10......................QDNLYFQSMSLRLERDGAVARLLIDRADR-RNAFSLDMWQRLPELLAEASGDDALRVLVVKSANGGAFCAGADIAELLANKDDAAHAANQQAINRAQYELARFRLPTVAMVEGDCIGGGCGIALACDMRIAAPA--ARFGITPAKLGLVYPLHDVKLLVDLVGPGQARRLMFTGGLIDANEAHRIGLVELLGESEDALVGQLA.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 210
55 -47.2005o34_A mol:protein length:294 Enoyl-CoA hydratase carB homologue  ali model follow..  18  37......................EDRFAAQESIECSRLGDGIALAEFSGA-HEQNPFSRARMRELTALMRELDADEKVRCVVLYGGAGRSFGVGGDFHEVSEFTGGDEVNAWIDDITDLYTTVAAISKPVIAAIDGYAIGVGLQISLCCDYRLGSEQ--ARLVMPEFRVGIACNFGGFM-LEAAAGRTVMQRMLLTCDEWPAERALADGLLHETVASPRLL-------------DRALELARTISGYTAEAVQSTRPR------------------------------------------VNAPFVAGLERIRREAKESHRRAFAAGEAQVRMRRVIGRS................................................................................................................................................................................................................................................................................................................................................................................................................................ 294
56 -47.2003qmj_A mol:protein length:256 Enoyl-CoA hydratase, EchA8_6  ali model follow..  21  3...........................GSMVTLQIDDDNRVRTLTLNRPEA-LNAFNEALYDATAQALLDAADDPQVAVVLLT-GSGRGFSAGTDLAEMQARITDPNFSEGKFGFRGLIKALAGFPKPLICAVNGLGVGIGATILGYADLAFMSST--ARLKCPFTSLGVAPEAASSYLLPQLVGRQNAAWLLMSSEWIDAEEALRMGLVWRICSPEELL-------------PEARRHAEILAAKPISSLMAVKHT------------------------------------------MVEPNRAQIAAASARENAHFAELMGAQANAAALADFTDRRR............................................................................................................................................................................................................................................................................................................................................................................................................................... 256
57 -47.0004k2n_A mol:protein length:281 Enoyl-CoA hydratase/carnithine racemase  ali model follow..  18  2.............SSGVDLGTENLYFQSMSDVIQLVREGAIATVTLNRPDR-MNALNLPMWRGLAEAFETISADRSIHVVILRGAGTKAFAPGADIEEFDTLRNAEQAKAYDLVMRKALDTVRACPQPVIAAIWGPCVGGGLELACCCDIRLSAKS--GKFGVPINKISVVMAYPELAQIRRVAGPAAALEILLEGRIMDADEAAAKRLVNRVVEDDAMDAEVAATAKRAAGAPLANRWHKAFIAR............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 233
58 -47.0005kjp_A mol:protein length:265 Enoyl-CoA hydratase  ali model follow..  24  7......................ESDAANTEPEVLVEQRDRILIITINRP-KAKNAVNAAVSRGLADAMDQLDGDAGLSVAILT-GGGGSFCAGMDLKAF------ARGENVVVEGRGLGFTERPPTKPLIAAVEGYALAGGTELALAADLIVAARD--SAFGIPEVKRGLVAGGGGLLRLPERIPYAIAMELALTGDNLPAERAHELGLVNVLAEPGTAL-------------DAAIALAEKITANGPLAVVATKRI------------------------------------------ITESRGWSPDTMFAEQMKILVPVFTSNDAKEGAIAFAERRR............................................................................................................................................................................................................................................................................................................................................................................................................................... 259
59 -46.9004kd6_A mol:protein length:275 Enoyl-CoA hydratase/isomerase  ali model follow..  19  2.............SSGVDLGTENLYFQSMSNDVLFSNHGRVAVITLNRPER-LNAWTTPMRETIIDALERFNRDPEVAAIIMTGAGNRAFSAGQDLSEAHDF-DGERAVAWVKEWQRYYTALRSLSKPLVMALNGTAAGSAFQVALLGDIRVGHPG--VRMGQPEINAGI-ASTTGPWIMNAMLGMSRTIELTLTGRLMEAEECHRIGLIHHLVDEDKVF-------------DKALEIATELAAKPPVAMRLDKQR------------------------------------------FREMTEPGFIDCIEAGERIQREAYDSGEPARMMEEFFSKRA............................................................................................................................................................................................................................................................................................................................................................................................................................... 268
60 -46.8004nek_A mol:protein length:252 Enoyl-CoA hydratase/carnithine racemase  ali model follow..  21  1............................MSELVLSHVEGGVQVVRMNRPDK-KNALIGEMYAALAEAFAKGEADDDVNVFLIL-GSQTDFSAGNDLPDFLTWEALSG-----SVADRFIRAVAGARKPVVAAVRGAAIGIGSTLLPHCDLVYAAPG--TRFHMPFINLGIVPEAGSSQTMPALAGHRRAAEMLMLGEPFGVDTAEAVGLINGVVPGEDLE-------------ETAMAAARKLAAKPRS-------------------------------------------ILVQIKALMKTPAEPIMDRLTREAAVFDTCLKGEALNEAVSAFKEKRA............................................................................................................................................................................................................................................................................................................................................................................................................................... 247
61 -46.8004f47_A mol:protein length:278 Enoyl-CoA hydratase EchA19  ali model follow..  19  4..............SMAPNTSETPANGESGPDALVEQRGHTLIVTMNRPSR-RNALSGEMMQIMVEAWDRVDNDPDIRCCILT-GAGGYFCAGMDLKAATKKPPGDSFKDYDPSRIDALLKGRRLKKPLIAAVEGPAIAGGTEILQGTDIRVAAES--AKFGISEAKWSLYPMGGSAVRLVRQIPYTVACDLLLTGRHITAAEAKEMGLVGHVVPDGQAL-------------TKALEIAEIIAANGPLAVQAILRT------------------------------------------IRETEGMHENEAFKIDTRIGIEVFLSDDAKEGPQAFAQKRK............................................................................................................................................................................................................................................................................................................................................................................................................................... 272
62 -46.8003qxi_A mol:protein length:265 Enoyl-CoA hydratase EchA1  ali model follow..  24  7......................SELNGDTEPEVLVEQRDRILIITINRP-KAKNSVNAAVSRALADAMDRLDADAGLSVGILT-GAGGSFCAGMDLKAF------ARGENVVVEGRGLGFTERPPAKPLIAAVEGYALAGGTELALATDLIVAARD--SAFGIPEVKRGLVAGGGGLLRLPERIPYAIAMELALTGDNLSAERAHALGMVNVLAEPGAAL-------------DAAIALAEKITANGPLAVAATKRI------------------------------------------ITESRGWSLDTRFAQQMKILFPIFTSNDAKEGAIAFAEKRP............................................................................................................................................................................................................................................................................................................................................................................................................................... 259
63 -46.7003qka_A mol:protein length:261 Enoyl-CoA hydratase, EchA5  ali model follow..  27  2........................PGSMVSDLVQVERNGPVTTVIINRP-QARNAVNGPTAAALYSAFAEFDRDESASVAVLC-GNGGTFCAGADLKAFGTAEANAVHRT---GPGPMGPSRMMLSKPVIAAVSGYAVAGGLELALWCDLRVAEQD--AVFGVFCRRWGVPLIDGGTVRLPRLIGHSRAMDMILTGRAVQADEALAIGLANRVVPNGQARQAAEELAAQAALPQQCLRSDRLSALQQ............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 218
64 -46.7004izb_A mol:protein length:275 Enoyl-CoA hydratase/isomerase family protein  ali model follow..  21  1.....................MTQDVTSGYSNLDLDLDNGVCVVTLNRPDK-RNALDVATIEELVTFFSTAH-RKGVRAVVLT-GAGDHFCAGLDLVEHWKADSADDFMHVCLRWHEAFNKMEYGGVPIIAALRGAVVGGGLELASAAHLRVMDQS--TYFALPEGQRGIFTGGGATIRVSDMIGKYRMIDMILTGRVYQGQEAADLGLAQYITEGSSFDKAMELADKIASNLPLTNFAICSAIS--------------------------------------------------------HMQNMSGLDAAYAEAFVGGIVNTQPAARERLEAFANKTAAR............................................................................................................................................................................................................................................................................................................................................................................................................................. 262
65 -46.7004qfe_A mol:protein length:259 Enoyl-CoA hydratase  ali model follow..  27  2........................PGSMVSEPVRIERNGPVTTVIIDRP-EARNAVNGPTAAALFAAFEEFDADDTASVAVLT-GANGTFCAGADLKAFGTPEANQVHRE---GPGPMGPSRMDLSKPVIAAISGYAVAGGLELALWCDLRVVDED--ATMGVFCRRWGVPLIDGGTVRLPRLIGHSRAMDLILTGRAVDAAEAYAIGLANRVVPTGQARQAAEELAADARLPQQCMRADRLSALHQ............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 218
66 -46.7001ef8_A mol:protein length:261 METHYLMALONYL COA DECARBOXYLASE  ali model follow..  20  1...........................MSYQYVNVVTINKVAVIEFNYG-RKLNALSKVFIDDLMQALSDLNRPEIRCIILRAPSGSKVFSAGHDIHELPS--GGRDPLSYDDPLRQITRMIQKFPKPIISMVEGSVWGGAFEMIMSSDLIIAAST--STFSMTPVNLGVPYNLVGIHNLTRDAGFHIVKELIFTASPITAQRALAVGILNHVVEVEELEDFTLQMAHHSEKAPLAIAVIKEELR.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 214
67 -46.6004z0m_A mol:protein length:269 Enoyl-CoA hydratase  ali model follow..  26  1............................MSDLVRVERKGRVTTVILNRP-ASRNAVNGPTAAALCAAFEQFDRDDAASVAVLW-GAGGTFCAGADLKAFGTPEANSVHRT---GPGPMGPSRMMLSKPVIAAVSGYAVAGGLELALWCDLRVAEED--AVFGVFCRRWGVPLIDGGTVRLPRLIGHSRAMDMILTGRGVPADEALAMGLANRVVPKGQARQAAEELAAQAALPQQCLRSDRLSALHQ............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 213
68 -46.6003trr_A mol:protein length:256 Probable enoyl-CoA hydratase/isomerase  ali model follow..  22  4...........................SMADEVLIEQRDRVLLITINRP-DARNAVNRAVSQGLAAAADQLDSSADLSVAIIT-GAGGNFCAGMDLKAFVS-------GEAVLSERGLGFTNVPPRKPIIAAVEGFALAGGTELVLSCDLVVAGRS--AKFGIPEVKRGLVAGAGGLLRLPNRIPYQVAMELALTGESFTAEDAAKYGFINRLVDDGQAL-------------DTALELAAKITANGPLAVAATKRI------------------------------------------IIESASWAPEEAFAKQGEILMPIFVSEDAKEGAKAFAEKRA............................................................................................................................................................................................................................................................................................................................................................................................................................... 250
69 -46.6004mou_A mol:protein length:294 Enoyl-CoA hydratase/isomerase family protein  ali model follow..  25  16.................SMSTVSEVARPRTGRISVAIADGVASVEISNL-AQRNALTKDMCLEIQELMPQLDADPDVAVVVLR-GAGDTFCAGASISELASVLDPQPDGSTADHLSRADSAIAALSKPAVALVDGACMGGGWQIASACDFIIANER--AVIGLTPAKIGIIYPRPGLERLVRLVGHANAKYILLTGQTFSAPEARALGLVADVVPSESFEEKCAALVRSRSRSRFSMHSMKRLVD.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 241
70 -46.5003p85_A mol:protein length:270 Enoyl-CoA hydratase  ali model follow..  20  11......................QGPGSMTDEILLSNTEERVRTLTLNRPQA-RNALSAALRDRFFGALADAETDDDVDVVIIT-GADPVFCAGLDLKELGG----------SSALPDISPRWPALTKPVIGAINGAAVTGGLELALYCDILIASEN--ARFADTHARVGLLPTWGLSVRLPQKVGIGLARRMSLTGDYLSAADALRAGLVTEVVPHDQLLGAARAVAASVGNNQNAVRALLTSYHRI............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 222
71 -46.4003qxz_A mol:protein length:265 enoyl-CoA hydratase/isomerase  ali model follow..  21  2.........................PGSMVTELHEEIRDGVAVLTLHGPST-RNSFTVELGRQLGAAYQRLDDDPAVRVIVLT-GAPPAFCSGAQISAAAETFAAPR--NPDFSASPVQPAAFELRTPVIAAVNGHAIGIGMTLALHADIRILAEE--GRYAIPQVRFGVAPDALAHWTLPRLVGTAVAAELLLTGASFSAQRAVETGLANRCLPAGKVL-------------GAALRMAHDIATNVAPES---------------------------------------AALTKRLLWDAQMTGMSAAEVAARETADHLRLMGSQDAAEGPRAFIDGRP............................................................................................................................................................................................................................................................................................................................................................................................................................... 258
72 -46.3003ot6_A mol:protein length:232 Enoyl-CoA hydratase/isomerase family protein  ali model follow..  19  1.........................SNAMSDLVSYHLDDGVATLTLNNG--KVNAISPDVIIAFNAALDQAEKD---RAIVIVTGQPGILSGGYDLKVMTS--SAEAAINLVAQGSTLARRMLSHPFPIIVACPGHAVAKGAFLLLSADYRIGVAG-PFSIGLNEVQIGMTMHHAGIELARDRLRKSAFNRSVINAEMFDPEGAMAAGFLDKVVSVEELQGAALAVAAQKKINMNAHKKTKLKVRKGL........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 216
73 -46.3003pe8_A mol:protein length:256 Enoyl-CoA hydratase  ali model follow..  23  3........................GSMADSPVLLVDTTDRVRTLTLNRPQS-RNALSAELRSTFFRALSDAQNDDDVDVVIVT-GADPVFCAGLDLKELGD----------TTELPDISPKWPDMTKPVIGAINGAAVTGGLELALYCDILIASEN--AKFADTHARVGLMPTWGLSVRLPQKVGVGLARRMSLTGDYLSAQDALRAGLVTEVVAHDDLLTAARRVAASVGNNQKAVRALLDSYHRI............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 212
74 -46.3003lke_A mol:protein length:263 Enoyl-CoA hydratase  ali model follow..  21  1...........................MSLSYVHTEIQNDALYITLDYPEK-KNGLDAELGTSLLEAIRAGNNETSIHSIILQSKHRAYFSSGPRLEDLLICASDQRLREVLHVLNHCVLEIFTSPKVTVALINGYAYGGGFNMMLACDRRIALRR--AKFLENFHKMGISPDLGASYFLPRIIGYEQTMNLLLEGKLFTSEEALRLGLIQEICENKQ------------ELQERVKNYLKAVSEGYVPAIAATKKL------------------------------------------LKGKAAEELKQQLEQETEELVALFKQTEIKKRLEALV................................................................................................................................................................................................................................................................................................................................................................................................................................... 255
75 -46.1003r9q_A mol:protein length:262 enoyl-coA hydratase/isomerase  ali model follow..  26  3......................GSMSEEMQPAVRVEKAGPVTTVILNRPHA-RNAVDGPTAAALLAAFTEFDADPEASVAVLW-GDNGTFCAGADLKAMGTDRGNELHPH---GPGPMGPSRLRLSKPVIAAISGHAVAGGIELALWCDLRVVEED--AVLGVFCRRWGVPLIDGGTIRLPRLIGHSRAMDLILTGRPVHANEALDIGLVNRVVARGQAREAAETLAAEAAFPQQCVRADRDSAIAQ............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 221
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Jaroszewski L, Slabinski L, Wooley J, Deacon AM, Lesley SA, Wilson IA, Godzik A. Genome pool strategy for structural coverage of protein families. Structure. 2008 Nov 12;16(11):1659-67.