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Query: [E] KOG2380 Prephenate dehydrogenase (NADP+), from COG1018

Results of FFAS03 search in PDB1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MAETLITKPPLSLSFTSLSSMLPSLSLSTANRHLSVTDTIPLPNSNSNATPPLRIAIIGFGNYGQFLAETLISQGHILFAHSRSDHSSAARRLGVSYFTDLHDLCERHPDVVLLCTSILSIENILKTLPFQRLRRNTLFVDVLSVKEFAKTLLLQYLPEDFDILCTHPMFGPQSVSSNHGWRGLRFVYDKVRIGEERLRVSRCESFLEIFVREGCEMVEMSVTDHDKFAAESQFITHTLGRLLGMLKLISTPINTKGYEALLDLAENICGDSFDLYYGLFVYNNNSLEVLERIDLAFEALRKELFSRLHGVVRKQSFEGEAKKVHVFPNCGENDASLDMMRSEDVVVKYEYNSQVSGSVNDGSRLKIGIVGFGNFGQFLGKTMVKQGHTVLAYSRSDYTDEAAKLGVSYFSDLDDLFEEHPEVIILCTSILSTEKVLESLPFQRLKRSTLFVDVLSVKEFPRNLFLQTLPQDFDILCTHPMFGPESGKNGWNNLAFVFDKVRIGMDDRRKSRCNSFLDIFAREGCRMVEMSCAEHDWHAAGSQFITHTVGRLLEKLSLESTPIDTKGYETLLKLVENTAGDSFDLYYGLFLYNPNAMEQLERFHVAFESLKTQLFGRLHSQHSHELAKSSSPKTTKLLTSLast
1 -67.6005t95_A mol:protein length:271 Prephenate dehydrogenase 1  ali model follow..  53  2....................................................................................................................................................................................................................................................................................................................................................................STSSSSQSLKIGIVGFGNFGQFLAKTMIKQGHTLTATSRSDYSELCLQMGIHFFRDVSAFLTADIDVIVLCTSILSLSEVVGSMPLTSLKRPTLFVDVLSVKEHPRELLLRELPEDSDILCTHPMFGPQTAKNGWTDHTFMYDK----VRIRDEVICSNFIQIFATEGCKMVQMSCEEHDRAAAKSQFITHTIGRTLGEMDIQSTPIDTKGFETLVKLKETTMRDSFDLYSGLFVYNRFARQELENLEHALHKVKETLMIQRTNGEQGHKRTES.......... 271
2 -59.8002f1k_A mol:protein length:279 prephenate dehydrogenase  ali model follow..  17  1............................................................................................................................................................................................................................................................................................................................................................................MKIGVVGLGLIGASLAGDLRRRGHYLIGVSRQQSTEKAVERQLVDEAGQDLSLLQTAKIIFLCTPIQLILPTLEKLI-PHLSPTAIVTDVASVKTAIAEPASQLWS---GFIGGHPMAGTAAQGIDGAEENLFVNAPYVLTPYTDPEQLACLRSVLEPLGVKIYLCTPADHDQAVAWISHLPVMVSAALIQACAGEKKLAQNLASSGFRDTSRVGGGNPELGTMMATYNQRLLKSLQDYRQHLDQLITLISNQQWPELHRLLQQTNGDRDKYVE.. 279
3 -58.4004wji_A mol:protein length:293 Putative cyclohexadienyl dehydrogenase and ADH prephenate dehydrogenase  ali model follow..  16  6.............................................................................................................................................................................................................................................................................................................................................................................TIALIGIGLIGSSIARDIREKQGTIVVTTRSEATKRAGELGLGDRYTLSAEAVEGADLVVVSVPVGASGAVAAEIA-AHLKPGAIVTDVGSTKGSVIAQMAPHLPKDVHFVPGHPIAGTEHSGPDAGFAGLFRGRWCILTPGTDEEAVARLRLFWETLGSMVDEMDPKHHDKVLAIVSHLPHIIAYNIVGTADDTESEVIKYSASGFRDFTRLAASDPTMWRDVCLHNKDILEMLARFSEDLASLQRAIRWGDGDKLFDLFTRTRAIRRSIVQAG 290
4 -56.8003b1f_A mol:protein length:290 Putative prephenate dehydrogenase  ali model follow..  19  1......................................................................................................................................................................................................................................................................................................................................................................AAAMEEKTIYIAGLGLIGASLALGIKRDHYKIVGYNRSDRSDIALERGIVDEATADKVFAALADVIILAVPIKKTIDFIKILADLDLKEDVIITDAGSTKYEIVRAAEYYLKDPVQFVGSHPMAGSHKSGAVAANVNLFENAYYIFSPLTKPNTIPALQDLLSGLHARYVEIDAAEHDCVTSQISHFPHIIASSLMKQAGDSHEMTKHFAAGGFRDMTRIAESEPGMWTSILLTNQEVLDRIENFKQRLDEVSNLIKARDENAIWAFFNQSRQIRKNM.... 289
5 -56.2003dzb_A mol:protein length:317 Prephenate dehydrogenase  ali model follow..  18  1.......................................................................................................................................................................................................................................................................................................................................................................MSLSKKTIYIAGLGLIGGSLALGIKRDHYEILGYNRSDYSNIALERGIVDRATGDKEFAPLADVIILAVPIKQTMAYLKELADLDLKDNVIITDAGSTKREIVEAAERYLTGNVQFVGSHPMAGSHKSGAIAADVTLFENAYYIFTPLTKETTIPELKDILSGLKSRYVEIDAAEHDRVTSQISHFPHLLASGLMEQAADAHEMTNHFAAGGFRDMTRIAESEPGMWASILMTNGPVLDRIEDFKKRLDHVADLIKAEDESAIWEFFDNGRKKRKEMEIHK 292
6 -55.8002pv7_A mol:protein length:298 T-protein [Includes: Chorismate mutase (EC 5.4.99.5) (CM) and Prephenate dehydrogenase (EC 1.3.1.12) (PDH)]  ali model follow..  17  3................................RESYANENQFGFKTINSDIHKIVIVGGYGKLGGLFARYLRASGYPISILDRED-------------WAVAESILANADVVIVSVPINLTLETIERLK-PYLTENMLLADLTSVKREPLAKMLEVHTG--AVLGLHPMFGADIASMAKQ----------VVVRCDGRFPERYEWLLEQIQIWGAKIYQTNATEHDHNMTYIQALRHFSTFANGLHLSKQPALSSPIYRLELAMIGRLFAQDAELYADIIMDKSENLAVIETLKQTYDEALTFFENNDRQGFIDAFHKVRDWFGDYSEQFLKESRQL............................................................................................................................................................................................................................................................................................................... 288
7 -55.6003ggg_D mol:protein length:314 Prephenate dehydrogenase  ali model follow..  17  20....................................................................................................................................................................................................................................................................................................................................................................KILKSLSMQNVLIVGVGFMGGSFAKSLRRSGGKIYGYDINPESSKAVDLGIIDTTSIAKVEDFSPDFVMLSSPVRTFREIAKKLS-YILSEDATVTDQGSVKGKLVYDLENILGKR--FVGGHPIAGTEKSGVEYSLDNLYEGKKVILTPKTDKKRLKLVKRVWEDVGGVVEYMSPELHDYVFGVVSHLPHAVAFALVDTLIHPEVDLFKYPGGGFKDFTRIAKSDPIMWRDIFLENKEVMKAIEGFEKSLNHLKELIVREAEEELVEYLKEVKIKRMEI.... 307
8 -53.3003ktd_A mol:protein length:341 Prephenate dehydrogenase  ali model follow..  16  10.............................................................................................................................................................................................................................................................................................................................................................................PVCILGLGLIGGSLLRDLHAANHSVFGYNRSRSGKSAVDEGFDVSADLEQRAAAEDALIVLAVPMTAIDSLLDAVHT--HAPNNGFTDVVSVKTAVYDAVKA-RNMQHRYVGSHPMAGTANSGWSASMDGLFKRAVWVVTFDQLFDGWKDVVQMALAVGAEVVPSRVGPHDAAAARVSHLTHILAETLAIVGDNGGALSLSLAAGSYRDSTRVAGTDPGLVRAMCESNAGLVKALDEALAILHEAREGL-TAEQPNIEQLADNGYRSRIRYEARS 295
9 -50.7005usc_A mol:protein length:381 Prephenate dehydrogenase  ali model follow..  16  7.................................................................................................................................................................................................................................................................................................................................................................KKESLEMRQMRKKVVLIGTGLIGGSLALAIKKDHVTITGYDIFQEQERAKELHVVDEIAVDQHACEEAHLIVFASPVEETKKLLHKLASFHLREDVIVTDVGSTKGSIMNEAEALFSKEISFIGGHPMAGSHKTGVESAKAHLFENAFYILTPHVPNEHVEELKDWLKGTGSHFLVLNTEEHDYVTGIVSHFPHLIAAGLVKQVEKDNPLIHQLAAGGFKDITRIASSSPKMWSDIVKQNRELMVLLKEWISEMEDLYDTVSSGDAGEIQNYFADAKEYRDSLPVRK 302
10 -38.9003c24_A mol:protein length:286 Putative oxidoreductase  ali model follow..  11  2..................................................................................................................................................................................................................................................................................................................................................................MVKDKNDVGPKTVAILGAGKMGARITRKIHDSAHHLAAIEIAPERDRLQGMGIPLTDGDG--WIDEADVVVLALPDNIIEKVAEDIV-PRVRPGTIVLILDAAAPYAGVMPER---ADITYFIGHPCHPPETDPAARTDYHGGIAKQAIVCAQGPEEHYAIGADICETMWSPVTRTHRVTTEQLAILEPGLSEMVAMPFVETMVHAVDECADRYGIDRQAALDFM--IGHLNVEIAMWFGYSPKVSDAALRLMEFAKDIVVKEDWREALNPAKVKQAAEL...... 282
11 -36.6004yt4_A mol:protein length:375 H(2)-forming methylenetetrahydromethanopterin dehydrogenase-related protein MJ1338  ali model follow..  10  21...................................................................................................................................................................................................................................................................................................................................................................NQNLYINKLNLPEKFGGEPPYGGMAIEFAEAGHDVVLAEPNNIMSDDLWKKVEDVVSDDVEAAKHGEIHVLFTPFKATFRIAKTII-EHVPENAVICNTCTVSPVVLYYSLEPIRKDVGISSMHPAAVP---GTPQHGHYVIGGKTTDGKELATEEQIKKAVELAKSAGKEAYVVPADVSSVVADMGSLVTAVALSGVLDYYTAPKKMIEQQVIMTLQTMASLVETSG-IEGMVKALNP------ELLIRSASSMKLLDRQKDLDAALEILQNLDETLKAEVEKA 313
12 -33.5006GGU Entity 1(prereleased)  ali follow..  10  1............................................................................................................................................................................................................................................................................................................................................................................MKLAILGAGCYRTHAASGIEMVGKPEIAMTHSTITMGAELKELAGVDEVDREAVADADFIMTWFPKGDMQPDIINKFIDDIKPGAIVTHACTIPTTKFYKIFEQKPETLNVTSYHPGAVPEMKG-----------QVYIAEGYASEDAIETLFELGQKARGNAYRLPAELLGPVCDMCSALTAITYAGILSYRDSVTSFAQMMAKESLEQITALMEKV-GIDKMEENLDPGA------LLGTADSMNFGASAEILPTVFEILEKRKK......... 344
13 -33.5004jjf_A mol:protein length:344 5,10-methenyltetrahydromethanopterin hydrogenase  ali model follow..  10  1............................................................................................................................................................................................................................................................................................................................................................................MKLAILGAGCYRTHAASGIEMVGKPEIAMTHSTITMGAELKELAGVDEVDREAVADADFIMTWFPKGDMQPDIINKFIDDIKPGAIVTHACTIPTTKFYKIFEQKPETLNVTSYHPGAVPEMKG-----------QVYIAEGYASEDAIETLFELGQKARGNAYRLPAELLGPVCDMCSALTAITYAGILSYRDSVTSFAQMMAKESLEQITALMEKV-GIDKMEENLDPGA------LLGTADSMNFGASAEILPTVFEILEKRKK......... 344
14 -32.0006HAC Entity 1(prereleased)  ali follow..  8  82............................................................................................................................................................................................................................................................................................................................................................................KEVMEAHLAGKAEDVMPAIRDA-KDSPKPPKGCIHFVNPEKVGLKVTSDDREAIEGADIVITWLPKGGSQPAIIEKFVDAIKEGAIVTHACTIPTPKFAKIFKDLREDLNIVSFHPGCVPEMKGQVY-----------LSEGYASEEAVEKLYKIAKISRGTAFKMPANLISPVCDMGSAVTAPVYAAILSYRDAVTDFAQMMADEAITQMLELM-RNEGIQNMENKLNPGA------LTGTADSMCFGPLSELLPASLKVLEEHKK......... 342
15 -29.9004yte_A mol:protein length:194 H(2)-forming methylenetetrahydromethanopterin dehydrogenase-related protein MJ0715  ali model follow..  12  10...................................................................................................................................................................................................................................................................................................................................................................NQRLYLEQLKVPEKFGGEPPYGGMAIEFAKAGHDVVLSEPNDVMSDDLWKKVEDVVSDDIEAAKHGEIHVLFTPFGRITLNIANTIIEHVPENAIICNTCTIPTPVLYRSLEGIRRDVGISSMHPTGGTPSQKYYTIAGKALEGKEYA-----TEDQINKLVELVKSVGKIPYVTPA............................................................................................................ 194
16 -25.3005t57_A mol:protein length:296 Semialdehyde dehydrogenase NAD-binding protein  ali model follow..  10  4...............................................................................................................................................................................................................................................................................................................................................................SSSGLVPRGSHMKEKIALFGAGKMGVRLAKNLLKSDYRVSHVEVSEVGKKRLKDELGLECVSTEAALDNVDVVILAVPDTIIGKIAAQIA-PQLRPGTMVMTLDAAAPFAGHLPDRPDLTYFVAHPCHPLIFNDETDPEARRDYFAKQSITSALMQGPEEAFDLGEAVAKVIYAPILRSYRLTVDQMALLEPGLSETICATLLQV-----------MREAMDETVRRGVPKEAARDFLLGHMNILGAVIFNEGAFSDACNKAIEFGKPRLMRDDWIKVFDREE...... 281
17 -19.9002yjz_A mol:protein length:201 METALLOREDUCTASE STEAP4  ali model follow..  13  1.................................MEKTCADEFPLTVDSSEKQGVVCIFGTGDFGKSLGLKMLQCGYSVVFGSRNP--QVSSLLPRGAEVLCYSEAASRSDVIVLAVHREHYDFLAELADS----KGRVLIDVSN-PESNAEYLAQLVPGAHVVKAFNTISAWALQSGTLDASRQVFVC--------GNDSKAKDRVMDIARTLGLTPLDQGSLVAAKEI........................................................................................................................................................................................................................................................................................................................................................................................................................... 189
18 -19.2002raf_A mol:protein length:209 Putative Dinucleotide-Binding Oxidoreductase  ali model follow..  14  1.......................................MGSDKIENLYFQGMEITIFGKGNMGQAIGHNFEIAGHEVTYYGSKD------------------QATTLGEIVIMAVPYPALAALAKQYATQL--KGKIVVDITN-DSSAAQELQQQLPDSQVLKAFNTTFAATLQSGQVNGKEPTTVLV------AGNDDSAKQRFTRALADSPLEVKDAGKLKRARELEAMGFM..................................................................................................................................................................................................................................................................................................................................................................................................................... 183
19 -18.0004huj_A mol:protein length:220 Uncharacterized protein  ali model follow..  13  1...................................MSSGVDLGTENLYFQSMTTYAIIGAGAIGSALAERFTAAQIPAIIANSRGPASLSSVTDRFSVKAVELKDALQADVVILAVPYDSIADIVTQVSD----GGQIVVDASN-GRLSTEIVSELVPGAKVVKAFNTLPAAVLAADPDKGTGSRVLFL------SGNHSDANRQVAELISSLGFAPVDLGTLAASGPIQQFGRP..................................................................................................................................................................................................................................................................................................................................................................................................................... 205
20 -17.9002vns_A mol:protein length:215 METALLOREDUCTASE STEAP3  ali model follow..  11  1........................MPEEMDKPLISLHLVDSDSSLAKVPDEAPKVGILGSGDFARSLATRLVGSGFKVVVGSRNPKRTARLFPSAAQVTFQEE-AVSSPEVIFVAVFREHYSSLCSLSDQ----AGKILVDVSN-RESNAEYLASLFPTCTVVKAFNVISAWTLQAGPRDGNRQVPIC--------GDQPEAKRAVSEMALAMGFMPVDMGSLASAWEVEAMPLR..................................................................................................................................................................................................................................................................................................................................................................................................................... 207
21 -17.8003d1l_A mol:protein length:266 Putative NADP oxidoreductase BF3122  ali model follow..  10  2...................................................................................................................................................................................................................................................................................................................................................................NAMKRSIEDTPIVLIGAGNLATNLAKALYRKGFRIVQVRTEESARELAQKVEAEYTTDLAEVNPYAKLYIVSLKDSAFAELLQGIVEGKREEALMVHTAGSIPMNVWE------GHVPHYGVFYPMQT-------SKQREVDFKEIPFFIEASSTEDAAFLKAIASTLSNRVYDADSEQHLAAVFTCNFTNHMYALALLKKYNLPFDVMLPLIDETARKVHELEPKT-------AQTGPAIRYDENVIGNHLRMLAD---DPAMQRLYELLSRSIHERQ...... 266
22 -16.9005n2i_A mol:protein length:232 Reduced coenzyme F420:NADP oxidoreductase  ali model follow..  14  1.................................MIMIMASKSSPHDLPDVSGLSIAVLGTGDQGRGLARRFAMAGHEVILGSRSQAVAAELGEGLPVRGMDNAGAAEAGDVVIVAVPWDGHRALLESLKDVL--AGKIVVDCVN-EGSAAEQAAAILPDSRVVAAFHHVSAVLLLDPEVEKVDLDVLVL-------GDDREATDVVRALAARIGVRGVYGGRLRNAHQVEAFTAN..................................................................................................................................................................................................................................................................................................................................................................................................................... 213
23 -16.7003qha_A mol:protein length:296 Putative oxidoreductase  ali model follow..  12  3...............................................................................................................................................................................................................................................................................................................................................................GSMTTNAAHTTEQLKLGYIGLGNMGAPMATRMTEWPGGVTVYDIREAMTPLAEAGATLADSVADVA--AADLIHITVLDDAQVREVVGELAGHAKPGTVIAIHSTISDTTAVELARDLKADIHIVDA-PVSGGAAAAARGELATMV---------GADREVYERIKPAFKHWAAVVIHAGEPGAGTRMKLARNMLTFTSYAAACEAMKLAEAAGLDLQALGRVVRHTDALTGGP....................................................... 226
24 -16.5003dtt_A mol:protein length:245 NADP oxidoreductase  ali model follow..  15  4..........................................DKIENLYFQGMKIAVLGTGTVGRTMAGALADLGHEVTIGTRDPKATLARAEPDHVHLAAFADVAAGAELVVNATEGASSIAALTAAGAENLA-GKILVDIAN-TDSLGEQIQRTFPEAKVVKTLNTMNASLMVDPGRAAGGDHSVFV------SGNDAAAKAEVATLLKSLG.......................................................................................................................................................................................................................................................................................................................................................................................................................................... 198
25 -16.3005y8g_A mol:protein length:295 Probable 3-hydroxyisobutyrate dehydrogenase  ali model follow..  11  2...........................................................................................................................................................................................................................................................................................................................................................................MTTIAFLGLGNMGAPMSANLVGAGHVVRGFDPAPTAASGAAAHGVAVFRSAPEAVAEADVVITMLPTGEVVRRCYTDVLAAARPATLFIDSSTISVTDAREVHALAESGMLQLDA-PVSGGVKGAAAATLAFMV---------GGDESTLRRARPVLEPMAGKIIHCGAAGAGQAAKVCNNM--VLAVQQIAIAEA--------------VLAEKLGLSAQSLFDVITGATGNCWAVHTNCPVPGPVPTSPANNDFK.................... 234
26 -16.2001jax_A mol:protein length:212 conserved hypothetical protein  ali model follow..  13  1....................................................MRVALLGTGNLGKGLALRLATLGHEIVVGSRREEKAEAKAAEYRRIAGKNEDAAEACDIAVLTIPWEHAIDTARDLKNIL--REKIVVSPLV-ERSAAEIVAEVLESEKVVSALHTIPAARFANLDEKFDWDVPVC--------GDDDESKKVVMSLISEIGLRPLDAGPLSNSRLVESLTPL..................................................................................................................................................................................................................................................................................................................................................................................................................... 194
27 -16.0003w6u_A mol:protein length:306 6-phosphogluconate dehydrogenase, NAD-binding protein  ali model follow..  19  1..............................................................................................................................................................................................................................................................................................................................................................MGSSSSGLVPRGSHMRVGFIGLGIMGGPMATHLLKAGFLAAVYNRTREKTKPFAEAGVYVAESPADLAKRVDVVIVMVS-PDVEQVLPSGVVEGARPGLIVVDMSTNSPDWARKFAERLAQGIEFLDA-PVTGGQKGAIEGTLTIMV---------GGKEELFHRLLPIFKAMGRDIVYMGPVGYGQAMKLVNQV--VVALNTVAMV................................................................................... 199
28 -15.9004gbj_A mol:protein length:297 6-phosphogluconate dehydrogenase NAD-binding  ali model follow..  10  1.......................................................................................................................................................................................................................................................................................................................................................................SNAMSEKIAFLGLGNLGTPIAEILLEAGYELVVWNRTASKAEPLTKLGATVVENAIDAITPGGIVFSVLA-AAVEELFSMELVEKLGKDGVHVSMSTISPETSRQLAQVHEWGAHYVGA-PIFARPEAVRAKVGNICL---------SGNAGAKERIKPIVENFVKGVFDFGDDP---AANVIKLAGNFMIACSLEMMGEAFTMAEK------------NGISRQSIYEMLTSTLFAAPIFQNYGKLVAS............................... 228
29 -15.8001yb4_A mol:protein length:295 tartronic semialdehyde reductase  ali model follow..  18  1.........................................................................................................................................................................................................................................................................................................................................................................SNAMKLGFIGLGIMGSPMAINLARAGHQLHVTTIGPVADELLSLGAVNVETARQVT-EFADIIFIMVP-PQVEDVLEHGCAKTSLQGKTIVDMSSISPIETKRFAQRVNEGADYLDA-PVSGGEIGAREGTLSIMV---------GGEQKVFDRVKPLFDILGKNITLVGGNGDGQTCKVANQI--IVALNIEAVS................................................................................... 187
30 -15.8003l6d_A mol:protein length:306 Putative oxidoreductase  ali model follow..  10  2....................................................................................................................................................................................................................................................................................................................................................................SLSDESFEFDVSVIGLGAMGTIMAQVLLKQGKRVAIWNRSPGKAAALVAAGAHLCESVKAALSASPATIFVLL-HATHEVLGMPGVARALAHRTIVDYTTNAQDEGLALQGLVNQGGHYVKG-MIVAYPRNVGHRESHSIH---------TGDREAFEQHRALLEGLAGHTVFLPWDEALAFATVLHAHAFAAMVTFFEAVG.................................................................................. 195
31 -15.7001i36_A mol:protein length:264 CONSERVED HYPOTHETICAL PROTEIN MTH1747  ali model follow..  15  1....................................................LRVGFIGFGEVAQTLASRLRSRGVEVVTSLEGRSPSTIERARTVGVTETSEEDVYSCPVVISAVTPGVALGAARRAGR---HVRGIYVDINNISPETVRMASSLIEKDAAIMGSVRASGRDAEEFMK----NRYGLNIEVRGREPGDASAIKMLRSSYTK-GVSALLWET-----TAAHRLGLEEDVLEMLEYT.......................................................................................................................................................................................................................................................................................................................................................................................................... 196
32 -15.5003zgy_A mol:protein length:309 R-IMINE REDUCTASE  ali model follow..  11  1.................................MPDNPSTKGRMMRNQQAEHTPVTVIGLGLMGQALAGAFLGAGHPTTVWNRTAAKAEPLVARGAKSAGSVAEAVAASPLVVVCVSDYDAVHALLDPLDGTALQGRTLVNLTSGTSAQARERAAWADGR----GADYLDGAILAGPAAIGTADAVVLL-------SGPRSAFDPHASALGGLGAGTTYLGAD---DAAGLVMMWSILNGFLQGAALLGTAGVDATTFAPFITQGIGTVADWLPGYARQIDDGAYPADAIDTHLATMEHLIHESEF.............................................................................................................................................................................................................................................................................................................................................. 268
33 -15.5005u5g_A mol:protein length:295 6-phosphogluconate dehydrogenase  ali model follow..  9  2...........................................................................................................................................................................................................................................................................................................................................................................NRVVGFIGLGRMGQAICRRLLASQMPVHVHNRSREKADDLIRQGAVWAPDIVALTRAARVLFVCTA-EAVQDFYHA--LACLEVGDIVVDLSTIAPETAEGLHAAFAQGADYIEC-PVSGGVEGALAGILSAIV---------SGRPEAYGLIRPLLEVFCATVTYVPEPGKAQRLKILNNLAESIVISQGLSQGLDLKSMADVFTSCRGRSAYMDVALGYALSGGASSNVSLGVRCKDLELARRRLPQDQSYPFSTLAMTTFDTVRQ......... 271
34 -15.4002i9p_A mol:protein length:319 3-hydroxyisobutyrate dehydrogenase  ali model follow..  9  2.............................................................................................................................................................................................................................................................................................................................................................SSGVDLGTENLYFQSMPVGFIGLGNMGNPMAKNLMKHGYPLIIYDVFPDACKEFQDAGEQVVSSPADVAEKADRIITMLPTSINAIEAANGILKKVKKGSLLIDSSTIDPAVSKELAKEVEKGAVFMDA-PVSGGVGAARSGNLTFMV---------GGVEDEFAAAQELLGCMGSNVVYCGAVGTGQAAKICNNM--LLAISMIGTAEA--------------NLGIRLGLDPKLLAKILNMSSGRCWSSDTYNPVPGVMDGVPSANNYQ.................... 251
35 -15.3005yeq_A mol:protein length:340 Ketol-acid reductoisomerase (NADP(+))  ali model follow..  8  16..........................................................................................................................................................................................................................................................................................................................................................................KEKRVAVLGYGSQGRAWALNLRDSGIKVSVGLEREGNSWKQAENDGFKPLRTEEAVRNSDIIIFLLPDMIQRTVYLERVKPYLKEGMDLVFAHGFNIHYRLIEPPSNVDVYMIAPKAPGPIVREYFAKGGGVPALVA----TYQDHSGKALQKALAVAKAIGATRAETETDLFGEQVDLVGGVMQLMRYAFVEAGYQPEVAYFETINEMKLIVDLVYEKG-KALDNI-RSGKFAEKWVEEYGKGANTIKEGMKEVDNSTEEKVGRSLRDIILRGKPKS 332
36 -15.3004ypo_A mol:protein length:333 Ketol-acid reductoisomerase  ali model follow..  8  13..........................................................................................................................................................................................................................................................................................................................................................................QGRKVGVIGYGSQGHAHSLSLRDSGVQVRVGLKQGSRSRPKVEEQGLDVDTPAEVAKWADVVMVLAPDTAQAEIFAGDIEPNLKPGDALFFGHGLNVHFGLIKPPADVAVAMVAPKGPGHLVRRQFVDGKGVP----CLVAVEQDPRGDGLALALSYAKAIGGTRAGVIKTTFKDETETDLFGEQTVLCGGTEELVKA----------GFEVMVEAGYPAELAYFEVLHELKLIVDLMAGTKERMRDILREIQDG--SFVHKLVADVEGGNKQL.... 299
37 -15.3002i76_A mol:protein length:276 Hypothetical protein  ali model follow..  12  2...................................................SLVLNFVGTGTLTRFFLECLKDRYEIGYILSRSIDRARNLAEVYGGKAATLEKHPELNGVVFVIVPDRYIKTVANHLN----LGDAVLVHCSGFLSSEI--------KKSGRASIHPNFSFSSLEKALEMKDQIVFGL-------EGDERGLPIVKKIAEEISGKYFVIPSEKHLAAVIASNFPVALAYLSKRIYTLLGLDEPELLIHTLMKVADNIKKMRVE-----SLTGPVKRGDWQVVEEERREYEK.................................................................................................................................................................................................................................................................................................................................................. 235
38 -15.3004e21_A mol:protein length:358 6-phosphogluconate dehydrogenase (Decarboxylating)  ali model follow..  10  2.............................................................................................................................................................................................................................................................................................................................................................SSGVDLGTENLYFQSMQIGMIGLGRMGADMVRRLRKGGHECVVYDLNNAVQALEREGIAGARSIEEFCAKLVKVVWLMVPAAVVDSMLQRM-TPLLAANDIVIDGGNSHQDDIRRADQMRAQGITYVDV-GTSGGIFGLE--RGYCLMIG---------EKQAVERLDPVFRTLAPGIGAATPGREKREGTAELGYLHCAGHFVKMVHNGIEYGLMAAYAEGLNILHH-ANAGKEGQGADAETAPLRNPDFYRYDLDLADITEVWRRGS...................... 267
39 -15.3001vpd_A mol:protein length:299 TARTRONATE SEMIALDEHYDE REDUCTASE  ali model follow..  15  1.......................................................................................................................................................................................................................................................................................................................................................................SNAMTMKVGFIGLGIMGKPMSKNLLKAGYSLVVSDRNPEAIADVIAAGAETASTAKAIAEQCDVIITMLP-PHVKEVAENGIIEGAKPGTVLIDMSSIAPLASREISDALKAGVEMLDA-PVSGGEPKAIDGTLSVMV---------GGDKAIFDKYYDLMKAMAGSVVHTGDIGAGNVTKLANQV--IVALNIAAMS................................................................................... 190
40 -15.2003obb_A mol:protein length:300 Probable 3-hydroxyisobutyrate dehydrogenase  ali model follow..  10  2..........................................................................................................................................................................................................................................................................................................................................................................HMKQIAFIGLGHMGAPMATNLLKAGYLLNVFDLVQSAVDGLVAAGASAARSARDAVQGADVVISMLPASQHVEGLDDGLLAHIAPGTLVLECSTIAPTSARKIHAAAREGLAMLDA-PVSGGTAGAAAGTLTFMV---------GGDAEALEKARPLFEAMGRNIFHAGPDGAGQVAKVCNNQ--LLAVLMIGTAEA--------------ALGVANGLEAKVLAEIMRRSSGGNWALEVYNPWPGVMENAPASRDYS.................... 238
41 -15.2003cky_A mol:protein length:301 2-hydroxymethyl glutarate dehydrogenase  ali model follow..  14  2.........................................................................................................................................................................................................................................................................................................................................................................EKSIKIGFIGLGAMGKPMAINLLKEGVTVYAFDLMEANVAAVVAQGAQACENNQKVAAASDIIFTSLPNAGIVETVPGGVLSACKAGTVIVDMSSVSPSSTLKMAKVAAEGIDYVDA-PVSGGTKGAEAGTLTIMV---------GASEAVFEKIQPVLSVIGKDIYHVGDTGAGDAVKIVNNL--LLGCNMASLA................................................................................... 189
42 -15.1003doj_A mol:protein length:310 Dehydrogenase-like protein  ali model follow..  11  3...............................................................................................................................................................................................................................................................................................................................................................SSSSGLVPRGSHMMEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGASVCESPAEVIKKCKYTIAMLS-CAALSVVFD-VLEQICEGKGYIDMSTVDAETSLKINEAIGKGGRFVEG-PVSGSKKPAEDGQ---------LIILAAGDKALFEESIPAFDVLGKRSFYLGQVGNGAKMKLIVNM--IMGSMMNAFS................................................................................... 200
43 -15.1003g0o_A mol:protein length:303 3-hydroxyisobutyrate dehydrogenase  ali model follow..  9  1.....................................................................................................................................................................................................................................................................................................................................................................MSLTGTDFHVGIVGLGSMGMGAARSCLRAGLSTWGADLNQACANLLAEGACGAAASAREFAGVVDALVILVV-AQVRQVLEDGVAHLMKPGSAVMVSSTISSADAQEIAAALTANLNMLDA-PVSGGAVKAAQGEMTVMA---------SGSEAAFTRLKPVLDAVASNVYRISDTP-HQLLAGVHIAAAAEAMALAARAGIPLDVMYDVVTHAAGNSWMFENRMQHVVDGDYTPRSAVDIFVKDLGLVADTAKAL........................... 259
44 -15.0003dfu_A mol:protein length:232 Uncharacterized Protein from 6-Phosphogluconate Dehydrogenase-Like Family  ali model follow..  13  2.......................................................................................................................................................................................................................................................................................................................................................................MQAPRLRVGIFDDGSSTVNMAEKLDSVGHYVTVLHAPEDI---------------------RDFELVVIDAHGVEGYVEKLS-AFARRGQMFLHTSLTHG--ITVMDPLETSGGIVMSAHPIG-----------------QDRWVASALDELGETIVGLLVGELGGSIVEIADDKRAQLAAALTYAGFLSTL----------------QRDASYFLDEFLGDPDVTSDIVSAQQFQALPSLDEVIAQYDSINNPGRQRLFRDLARRQAEISRAQD...... 221
45 -15.0004ezb_A mol:protein length:317 uncharacterized conserved protein  ali model follow..  12  10...................................................................................................................................................................................................................................................................................................................................................................ENLYFQSMMTTIAFIGFGEAAQSIAGGLGGRNAARLAAASGALRARAAELGVEPLDDVAG--IACADVVLSLVVGAATKAVAASAA-PHLSDEAVFIDLNSVGPDTKALAAGAITGKGSFVEG-AVMARVPPYAEKVPILVA-------------RRAVEVAERLNALGMNLEAVGETPGQ--ASSLKMIRSVMIKGVEALLIEA-------------SSAERAGVTERILDSVQVADYYLSRTFEHGARRVTEMTEAAETIESFGLNAPMSRAACETIAAAHAA 284
46 -15.0001np3_A mol:protein length:338 Ketol-acid reductoisomerase  ali model follow..  10  7..........................................KDCDLSIIQGKKVAIIGYGSQGHAHACNLKDSGVDVTVGLRSGSATVAKAEAHGLKVADVKTAVAAADVVMILTPDEFQGRLYKEEIEPNLKKGATLAFAHGFS---IHYNQVVPRADLDVIMIAPKAPGHTVRSEFVKGGGIPDLIAIYQDASGNAKNVALSYACGVGGGRTGIIETTFKDQAVLCGGCVELVKAGFETLVEAGYAPEMAYFECLHELKLIVDLMYEGGINALKRIQ-DGEYAKMFITEGAANYPSMTAYRRNNAAHPIEQIGEKLRAMMPWIAANKIVDKSK................................................................................................................................................................................................................................................................................................................ 337
47 -15.0004xiy_A mol:protein length:338 Ketol-acid reductoisomerase  ali model follow..  10  15..........................................................................................................................................................................................................................................................................................................................................................................QSKKVAIIGYGSQGHAHACNLKDSGVDVYVGLRAGSASVAKAEAHGLTVKSVKDAVAAADVVMILTPDEFQGRLYKDEIEPNLKKGATLAFAHGFSIHYNQVVPRADLDVIMIAPKAPGHTVRSEFVRGGGIPDLIA----VYQDASGNAKNLALSYACGVGGGRTTFKDETETDLFGEQAVLCGGCVELVKAGNMNYSISNNAEYGEYVTGPEVINEQSRQAMRNALQDGEYAKMFITEGAANYPSMTAYRRNNAAHQIEVVGEKLRTMANKIVDKT 336
48 -15.0004d3d_A mol:protein length:310 IMINE REDUCTASE  ali model follow..  10  2................................KSNSQNEKNGSETTNAVGNRKSVTVIGLGPMGQAMADVFLEYGYSVTVWNRTSSKADQLVAKGAIRVSTVNEALAANELVILSLT-NVMYSILEPVSE--NLFGKVLVNLSSDTPEKARKAAKWLEDR----GARHITGGVQVPPSGIGKSESYTYY-------SGDRVVFEAHRETLEVLTSSDYRGEDPGLAMLYYQIQMDTAMLSYLHALAIANANGITAEQFLPYASAMMSSLPKFVEFYTPRLDEGEHPGDRLAMGLASVEHVVHTTQE.............................................................................................................................................................................................................................................................................................................................................. 268
49 -15.0005je8_A mol:protein length:302 3-hydroxyisobutyrate dehydrogenase  ali model follow..  15  2......................................................................................................................................................................................................................................................................................................................................................................SAKDPMKKIGFIGLGNMGLPMSKNLVKSGYTVYGVDLNKEAEASFEKEGGIIGLSISKLAETCDVVFTSLPSPRAVEAVAEGLFENGHSNVVFIDTSTVSPQLNKQLEEAAEKKVDFLAA-PVSGGVIGAENRTLTFMV---------GGSKDVYEKTESIMGVLGANIFHVSEQ------TTVKLINNLLIGFYTAGVSEALTLAKKNNMDLDKMFDILNVSY.......................................................... 217
50 -14.9003pef_A mol:protein length:287 6-phosphogluconate dehydrogenase, NAD-binding  ali model follow..  14  2............................................................................................................................................................................................................................................................................................................................................................................QKFGFIGLGIMGSAMAKNLVKAGCSVTIWNRSPEKAEELAALGAERAATPCEVVESCPVTFAMLA-AAAEEVCKHGVLEGIGEGRGYVDMSTVDPATSQRIGVAVAKGGRFLEA-PVSGSKKPAEDGT---------LIILAAGDRNLYDEAMPGFEKMGKKIIHLGDVGKGAEMKLVVNM--VMGGMMACFC................................................................................... 186
51 -14.9002uyy_A mol:protein length:316 N-PAC PROTEIN  ali model follow..  14  16...................................................................................................................................................................................................................................................................................................................................................................SMGSITPTDKKIGFLGLGLMGSGIVSNLLKMGHTVTVWNRTAEKCDLFIQEGARLGRTPAEVVSTCDITFACVS-KAAKDLVPSGVLQGIRPGKCYVDMSTVDADTVTELAQVISRGGRFLEA-PVSGNQQLSNDGMLVILA---------AGDRGLYEDCSSCFQAMGKTSFFLGEVGNAAKMMLIVNM--VQGSFMATIA................................................................................... 209
52 -14.9005ocm_A mol:protein length:291 NAD_Gly3P_dh, NAD-dependent glycerol-3-phosphate dehydrogenase  ali model follow..  12  1.........................................................................................................................................................................................................................................................................................................................................................................MRDTDVTVLGLGLMGQALAGAFLKDGHATTVWNRSEGKAGQLAEQGAVLASSARDAAEASPLVVVCVS-AAVRAVLDPLGD--VLAGRVLVNLTSGTSEQARATAEWAAEGITYLDG-AIMAIPQVVGTADAFLLY---------SGPEAAYEAHEPTLRSLGAGTTYLGAD........................................................................................................... 162
53 -14.8003pdu_A mol:protein length:287 3-hydroxyisobutyrate dehydrogenase family protein  ali model follow..  11  1...........................................................................................................................................................................................................................................................................................................................................................................MTTYGFLGLGIMGGPMAANLVRAGFDVTVWNRNPAKCAPLVALGARQASSPAEVCAACDITIAMLA-AAAREVCFG-VLEGIGGGRGYIDMSTVDDETSTAIGAAVTAGGRFLEA-PVSGTKKPAEDGT---------LIILAAGDQSLFTDAGPAFAALGKKCLHLGEVGQGARMKLVVNM--IMGQMMTALG................................................................................... 186
54 -14.8005a9r_A mol:protein length:290 IMINE REDUCTASE  ali model follow..  11  1.......................................................................................................................................................................................................................................................................................................................................................................MTDQNLPVTVAGLGPMGSALAAALLDRGHDVTVWNRSPGKAAPLVAKGARQADDIVDAVSASRLLVVCLA-DALYSALGPARE--ALRGRVVVNLNSGTPKEANEALRWAERGTGYLDG-AIMVPPAMVGHPGSVFLY---------SGSAEVFEEYKETLAGLGDPVHLGT----EAGLAVLYNTALLSMMYSSMNGFLHAAALVGSAGVPAAEFTKLAVDW.......................................................... 209
55 -14.7004dll_A mol:protein length:320 2-hydroxy-3-oxopropionate reductase  ali model follow..  12  13...............................................................................................................................................................................................................................................................................................................................................................YFQSMTVESDPYARKITFLGTGSMGLPMARRLCEAGYALQVWNRTPARAASLAALGATIHEQARAAARDADIVVSMLENGAVVQLFAQGVAAAMKPGSLFLDMASITPREARDHAARLGAGIAHLDT-PVSGGTVGAEQGTLVIMA---------GGKPADFERSLPLLKVFG-RATHVGPHGSGQLTKLANQM--IVGITIGAVA................................................................................... 208
56 -14.7004oqz_A mol:protein length:289 Putative oxidoreductase YfjR  ali model follow..  12  2...........................................................................................................................................................................................................................................................................................................................................................................SQSVTVIGLGPMGQAMAAAYLDRGYEVTLWNRTASRADALVARGAKLAATPEQALSANELVILSLI-DAMYGVLEGAEE--AVAGRVLVNLSSDTPEKARAAARRVAEGGTHLTG-GVLSPPPGIGSPDMSTFY---------SGPRAAYDQHRAALEVITGKTDYRGED........................................................................................................... 161
57 -14.7004d3s_A mol:protein length:293 IMINE REDUCTASE  ali model follow..  9  1....................................................................................................................................................................................................................................................................................................................................................................MTNTKAKKSPVTLIGLGPMGQAMAGALLEAGYELTVWNRTKAKAEALAERGAAVADSPAEALRAGGPVLLSLT-AVMYRVLEGAES--DLKGRTILNLGSDTPAASRAAAAWAEGGARYVTG-GVMSPAPGIGSSSVFSFY---------SGDRAAFEENKALLEVLTATDFRGE----DPGLAQVYYQILLDALAVARAEGVPVGTITPYLIEGNDMAMFFEGTSAAVAEGRFPGDEDRISMDAASMEHVVQTSRDVDTALPEAVLSLFRRGLD......... 274
58 -14.6001yrl_A mol:protein length:491 Ketol-acid reductoisomerase  ali model follow..  10  36..................................................QGKKVVIVGCGAQGLNQGLNMRDSGLDISYALRKEAIAEKRASWRKATENTYEELIPQADLVINLTPDKQHSDVVRTVQ-PLMKDGAALGYSHGFN---IVEVGEQIRKDITVVMVAP--CPGTEVREEYKRGFGVPTLIAVHPENDPKGEGMAIAKAWAAATGGHVLESSFVAEVKLCGMLQAGSLLCFDKLVEEGTDPAYAEKLIQFGWETITEALKQGGITMMDRLSNPAKLSEQLKEIMAPLFQKHMDDIISG-------------EFSSGMMADWANDDKKLLTWREETGKTAFETAPQYEGKIGEQEYFDKGVLMIAMVKAGVELAMVDSGII-SLHELPLIANTIARKRLYEMNVVISDTAEYGNYLFSYACVPLLKPFMAELQPGDLGKAIPEGAVDAIRSHAIEQVGKKLRGYMTDMKRIAVAG............................................................................................................................................................. 491
59 -14.5005e4r_A mol:protein length:490 Ketol-acid reductoisomerase  ali model follow..  10  1...................................MAKIYKDEDISLEPIKNKTIAILGYGSQGRAWALNLRDSGLNVVVGLERQGDSWRRAIDDGFKPMYTKDAVAIADIIVFLVPDMVQKSLWLNSVKDFMKKGADLVFAHGFN---IHFKIIEPPKDSDVYMIAP--SPGPIVRRSYEMGGGVPA--LVAVYQNVSGEALQKALAIAKGIGCARAGVIESTFKELVGGIMELIKASFETLVEEGYQPEVAYFETVNELKLIVDLIYEKG----AKYGGITVGKFIIDKSVRDKMKIVLERIRSG--EFAREWIKEYERGMPTVFKELSELEGSTIETVGRKLREMMFRGMKQISSHETDLFGEQVIL-VGGIMELIKASLVEEGYQ-TVNELKLIVDLIYEKGLTGMLRAVSDTAKYGGI-------KSVRDKMKIV-LERIRSGEFAREWIKEYERGMPTVFKELSE----LEGSTI............................................................................................................................................................... 461
60 -14.5005g6r_A mol:protein length:295 IMINE REDUCTASE  ali model follow..  11  2...........................................................................................................................................................................................................................................................................................................................................................................SKHIGIFGLGAMGTALAAKYLEHGYKTSVWNRTTAKAIPLVEQGAKLASTISEGVNANDLIIICLL-QVVEDALRDALQ--TLPSKTIVNLTNGTPNQARKLADFVTSGARYIHG-GIMAVPTM--------IGSPHAVLLYSGESLELFQSIESHLSLLGMSKYLGT............................................................................................................. 160
61 -14.4004oqy_A mol:protein length:290 (S)-imine reductase  ali model follow..  13  1.........................................................................................................................................................................................................................................................................................................................................................................MSKQSVTVIGLGPMGQAMVNTFLDNGHEVTVWNRTASKAEALVARGAVLAPTVEDALSANELIVLSLT-DAVYAILEPVTG--SLSGKVIANLSSDTPDKAREAAKWAAKGAKHLTG-GVQVPPPLIGKPESSTYY---------SGPKDVFDAHEDTLKVLTNADYRGE----DAGLAAMYYQAQMTIFWTTMLSYYQTLALGQANGVSAKELLPYATMMTSMMPHFLVDSADYPGDVDRLAMGAASVDHVLHTHQDAGVSTVLPAA........... 260
62 -14.4004xdz_A mol:protein length:343 Ketol-acid reductoisomerase  ali model follow..  10  18............................................................................................................................................................................................................................................................................................................................................................................KTIAILGYGSQGRAWALNLRDSGLNVVVGLERQGDSWRRAIDDGFKPMYTKDAVAIADIIVFLVPDMVQKSLWLNSVKDFMKKGADLVFAHGFN---IHFKIIEPPKDSDVYMIAPKSPGPIVRRSYEMGGGVPALVAVYQNVSG-EALQKALAIAKGIGCARAGVIESTFKELVGGIMELIKASFETLVEEGYQPEVAYFETVNELKLIVDLIYEKG-IVLERI-RSGEFAREWIKEYERGMPTVFKELSELEGSTIETVGRKLREMMFRGMKQ. 331
63 -14.4001wp4_A mol:protein length:289 3-hydroxyisobutyrate dehydrogenase  ali model follow..  12  1...........................................................................................................................................................................................................................................................................................................................................................................MEKVAFIGLGAMGYPMAGHLARRFPTLVWNRTFEKALRHQEEFGS--EAVPLERVAEARVIFTCLPTTREVYEVAEALYPYLREGTYWVDATSGEPEASRRLAERLREGVTYLDA-PVSGGTSGAEAGTLTVML---------GGPEEAVERVRPFLA-YAKKVVHVGPVGAGHAVKAINNA--LLAVNLWAAG................................................................................... 180
64 -14.2003qsg_A mol:protein length:312 NAD-binding phosphogluconate dehydrogenase-like protein  ali model follow..  11  10...................................................................................................................................................................................................................................................................................................................................................................ENLYFQSNAMKLGFIGFGEAASAIASGLRQAGADMAAYDAASARPRAEELGVSCKASVAE-VAGECDVIFSLVTAQAALEVAQQAG-PHLCEGALYADFTSCSPAVKRAIGDVISRAVAVMSAVKVDGDGARRFQAAFTLYGCRIEVLDGEVGGAALLKMCRSAVLK-GLEALFLEA-----AAAEKMGLADRVLASLDASFPEHLYLVERNLEHADRRAHELAEAGYRRLTRVAQVRAALKQRPGDVRAWLRSLANAEDA........................ 306
65 -14.1005ojl_A mol:protein length:298 Imine reductase  ali model follow..  10  1.....................................................................................................................................................................................................................................................................................................................................................................MATTTTTTKLTIFGLGAMGTAMATQFLKQGHTPTVWNRTAAKANPLVEQGAHLAATIPAAIAASPLLIFCLL-AAVEQTLAAGPP--SLAGKTILNLTNGTPSQARRLATLASAGARYFHG-GIMATPDMIGAPHAVILYSG-------GGSAETYASVEGVLAVLGSGKYLGDDAGSASLHGLFAGFLHATALVRSEGEGVSATEFLGLLAPWLQAMTGYLGL........................................................... 225
66 -14.1004tsk_A mol:protein length:350 Ketol-acid reductoisomerase  ali model follow..  10  18............................................................................................................................................................................................................................................................................................................................................................................KRIAVIGYGSQGHAHAQNLRDSGFDVVIGLRPGSSWAKAEADGFRVMAVGE-AVEESDVIMILLPDERQPAVYEREIRPYLTAGKALAFAHGFN---IHFSQIQPPKDVDVFMVAPKGPGHLVRRVYEAGGGVPALIAVHQDASG-QAKDLALAYARGIGAGRAGILTTTFREETGGLSALIKAGFETLVEAGYQPEIAYFECLHEMKLIVDLIYEGG-RILADI-QSGAFAKSWILENQANRPMFNAINRRELEHPIEVVGRKLRSMMPFIKAKR 331
67 -13.9004kqw_A mol:protein length:350 Ketol-acid reductoisomerase  ali model follow..  11  18..........................................QDVDPKVIQGLKVGIIGYGSQGHAHALNLMDSGVDVRVGLREGSSSWKTAEEAGLKVTDMDTAAEEADVIMVLVPDEIQPKVYQEHIAAHLKAGNTLAFAHGFN---IHYGYIVPPEDVNVIMCAP--GPGHIVRRQFTEGSGVPD--LACVQQDATGNAWDIVLSYCWGVGGARATFAEETEEDLFGEQAVLCGGLVELVKAG---------------FETLTEAGYPPELAYFECYHEMKMIVDLMYE-YYAGPKVINEQSREAMKEILKRIQDGSFAQEFVDDCNNGHKRLLEQREAINTHPIETTGAQIRSMFSWIKKEDL................................................................................................................................................................................................................................................................................. 343
68 -13.8002b0j_A mol:protein length:358 5,10-methenyltetrahydromethanopterin hydrogenase  ali model follow..  12  36..EIALTHSSITYGAELLHLV----DVKEVIVSDPCFAEEPGLVVIDEFDPKEVMEAHLSGNPESIMPKIREVKAKELPKPPKACIHLVHPEDVGLKVTSDDREAVEGADIVITWLP-NKQPDIIKKFA-DAIPEGAIVTHACTIPTKFAKIFKDLGREDLNITSYHPGCVPEMKGQ-------------VYIAEGYASEEAVNKLYEIGKIARGKAFKMPANLIGPVCDMCSAVTATVYAGLLAYRDAVTKILGAPADFAQMMADEALTQIHNL---MKEKGIANMEEALDPAALLGTADSMCFGPLAEILPTALKVLEKHKVVE.......................................................................................................................................................................................................................................................................................................................... 344
69 -13.6004xr9_A mol:protein length:456 CalS8  ali model follow..  10  9.............................................DPGEPSPLKVVIAGAGYVGTCLAVTLAGRGAEVVAVDSDPGTVADLRAGRCRLPETSYDPVGAADVVIVTVGTDQLVAACEQIA-PRLRAGQLVILKSTVSPGTTRTLVAPLLESGGLVHERDFFCPERLAEGVALAQVRTLPVVVGGCGPRSAAAAERFWRSALGV---DVRQVPSAESAEVVKLATNWWIDANVAIANELARYCA----VLGVDVLDVIGAANTLPKGSSMVNLLLPGVGVGGSCLTKDPWMAWRDGRDRGVSL--RTVETARAVNDDMPRHTAAV-----------------IADELVKLGRDRNDTTIAVLGAAFKNDTVVAALRDSGFRVRIFDPLADPAEIVARFGTAPAASLDEAVSGAGCLAFLAGHRQFHELDFGALAERVDEPCLVFDGRMH....................................................................................................................................................................................... 435
70 -13.6002ahr_A mol:protein length:259 putative pyrroline carboxylate reductase  ali model follow..  13  1.........................................................................................................................................................................................................................................................................................................................................................................SNAMKIGIIGVGKMASAIIKGLKQTPHELIISGSSLERSKEIAEQLLPYAMSHQDLIDQVDLVILGIKPQLFETVLKPL-----HFKQPIISMAA----SLQRLATFVGQDLPLLRIMP---NAQILQSSTAL--------TGNALVSQELQARVRDLTDSFG-STFDISEKDFDTFTALAGSSPAYIYLFIEALAKAGVKNGIP--AKALEIVTQTVLASASN---LKTSSQSPHDFIDAICSPGGTTIAGLMELERLGLTATVSSA........... 248
71 -13.6001yqg_A mol:protein length:263 pyrroline-5-carboxylate reductase  ali model follow..  12  1............................................................................................................................................................................................................................................................................................................................................................................MNVYFLGGGNMAAAVAGGLVKQGYRIYIANRGAEKRERLEKELGVETSATLPELHSDDVLILAVKPQDMEAACKNIR----TNGALVLSVAA----SVGTLSRYLGGTRRIVRVMP---PGKIGLGVSGM--------YAEAEVSETDRRIADRIMKSVGLTVWLDDEEKMHGITGISGSGPFYLLDALQNAAIRARALSLATFKGAVALAEQTGEDFEKLQKNVTSKGGTTHEAVEAFRR--HRVAEAISEGVCACVRRSQEMERQYQ....... 263
72 -13.6005w3k_A mol:protein length:340 Ketol-acid reductoisomerase (NADP(+))  ali model follow..  13  18............................................................................................................................................................................................................................................................................................................................................................................KKIAVVGYGSQGHAHAQNLKDNGYDVVIGIRPGRSDKAKEDGFDVFP---AEAVKQADVIMVLLPDEIQGDVYKNEIEPNLEKHNALAFAHGFN---IHFGVIQPPADVDVFLVAPLFGIQQDASGQARNIALSYAKGIGATRAGVIETTFKEETETDLFGEQAVLCGGVSKLIQSGFETLVE--ELAYFEVLHEMKLIVDLMYEGGMENVRYSISNTAEVLTDI-QNGNFSNRFIEDNKNGFKEFYKLREEQHGHQIEKVGRELREMMPFIKSKS 331
73 -13.5004xdy_A mol:protein length:338 Ketol-acid reductoisomerase  ali model follow..  10  17............................................................................................................................................................................................................................................................................................................................................................................KTIAVMGYGAQGDAQANCLKDSGINVVIGETEPSWEKAKEDGFEVLP---DKAAEKGDVVHILLPDEVQPAIYENQIKPQLKAGKALCFSHGFN---ICFKRIVPPEDVDVIMVAPKAPGTEERKAYLEGFGVPGLVAVKQNPSG-EAREVALAMTKAMHAGILECTFEQQCVLCGGLVELMRNGFEVLVEAGYPPEMAYFECVHEMKLIVDLVWQGGIEALKRVENGENEWVDEYKRGIPFLKASREKMGEHQVETVGAEIRKLFAQK....... 332
74 -13.1003fr7_A mol:protein length:525 Putative ketol-acid reductoisomerase (Os05g0573700 protein)  ali model follow..  11  3AAPPAVGAAMPSLDFDTSVFNKEKVSLAGHEEYIVRGGRNLFPLLPEAFKGIKQIGVIGWGSQGPAQAQNLRDSLAEAKSDIVSKSFDEARAAGFTETLGDIWETVSGSDLVLLLISDAAQADNYEKIF-SHMKPNSILGLSHGFLLGHLQSAGLDFPKNISVIAVCPGMGPSVRRLYVQGKEINGAGINSSFAVHQDVDGRATDVALGWSVASPFTFATTLEQEYKLLGAVHGIVEALFRRYTEQGMDEEMAYKNTVEGITGIISKTISKKGMLEVYNSLTEEGKKEFNKAYSASFYPCMDIL-----YECYEDVASGSEIRSVVLAGRRFYEKEGLPAFPMGNIDQTRMWKVGEKVRSTRPENDLGPLHPFTAGVYVAEVLRKKGHEIINESVIESVDSLNPFGVAFMVDNCSTTARLGSRFDYILTQQAFVTVDKDAPINQDLISNFMSDPVHGAIEVCAELRPTVDISVPANADRPELRQSS.......................................................................................................................................................... 525
75 -13.1003tri_A mol:protein length:280 Pyrroline-5-carboxylate reductase  ali model follow..  13  2..................................................NTSNITFIGGGNMARNIVVGLIANGRICVTNRSLDKLDFFKEKCGVHTTQDNRQGALNADVVVLAVKPHQIKMVCEELKDILSETKILVISLAV----TTPLIEKWLGKASRIVRAMPSVRAGATGL---------------FANETVDKDQKNLAESIMRAVGLVIWVSSEDQIEKIAALSGSGPAYIFLIMEALQETAELLTEQTVLGAARMALETEQSVVQLRQFVTSPGGTTEQAIKVLES--GNLRELFIKALTAAVNRAKELSKTVDQE........................................................................................................................................................................................................................................................................................................................... 275
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Ye Y, Godzik A. Multiple flexible structure alignment using partial order graphs. Bioinformatics. 2005 Mar 3;