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Query: [G] KOG2653 6-phosphogluconate dehydrogenase, from COG1018

Results of FFAS03 search in PDB1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MSADFGLIGLAVMGQNLILNAADHGFTVCAYNRTQSKVDHFLANEAKGKSIIGATSIEDFISKLKRPRKVMLLVKAGAPVDALINQIVPLLEKGDIIIDGGNSHFPDSNRRYEELKKKGILFVGSGVSGGEEGARYGPSLMPGGSEEAWPHIKNIFQSISAKSDGEPCCEWVGPAGAGHYVKMVHNGIEYGDMQLICEAYDIMKRLGGFTDKEISDVFAKWNNGVLDSFLVEITRDILKFDDVDGKPLVEKIMDTAGQKGTGKWTAINALDLGMPVTLIGEAVFARCLSALKNERIRASKVLPGPEVPKDAVKDREQFVDDLEQALYASKIISYAQGFMLIREAAATYGWKLNNPAIALMWRGGCIIRSVFLGQITKAYREEPDLENLLFNKFFADAVTKAQSGWRKSIALATTYGIPTPAFSTALSFYDGYRSERLPANLLQAQRDYFGAHTFRVLPECASDNLPVDKDIHINWTGHGGNVSSSTYQALast
1 -124.0002p4q_A mol:protein length:497 6-phosphogluconate dehydrogenase, decarboxylating 1  ali model follow..  100  3MSADFGLIGLAVMGQNLILNAADHGFTVCAYNRTQSKVDHFLANEAKGKSIIGATSIEDFISKLKRPRKVMLLVKAGAPVDALINQIVPLLEKGDIIIDGGNSHFPDSNRRYEELKKKGILFVGSGVSGGEEGARYGPSLMPGGSEEAWPHIKNIFQSISAKSDGEPCCEWVGPAGAGHYVKMVHNGIEYGDMQLICEAYDIMKRLGGFTDKEISDVFAKWNNGVLDSFLVEITRDILKFDDVDGKPLVEKIMDTAGQKGTGKWTAINALDLGMPVTLIGEAVFARCLSALKNERIRASKVLPGPEVPKDAVKDREQFVDDLEQALYASKIISYAQGFMLIREAAATYGWKLNNPAIALMWRGGCIIRSVFLGQITKAYREEPDLENLLFNKFFADAVTKAQSGWRKSIALATTYGIPTPAFSTALSFYDGYRSERLPANLLQAQRDYFGAHTFRVLPECASDNLPVDKDIHINWTGHGGNVSSSTYQA 491
2 -119.0001pgn_A mol:protein length:482 6-PHOSPHOGLUCONATE DEHYDROGENASE  ali model follow..  66  1AQADIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGTKVLGAHSLEEMVSKLKKPRRIILLVKAGQAVDNFIEKLVPLLDIGDIIIDGGNSEYRDTMRRCRDLKDKGILFVGSGVSGGEDGARYGPSLMPGGNKEAWPHIKAIFQGIAAKVTGEPCCDWVGDDGAGHFVKMVHNGIEYGDMQLICEAYHLMKDVLGLGHKEMAKAFEEWNKTELDSFLIEITASILKFQDADGKHLLPKIRDSAGQKGTGKWTAISALEYGVPVTLIGEAVFARCLSSLKDERIQASKKL-KGPQNIPFEGDKKSFLEDIRKALYASKIISYAQGFMLLRQAATEFGWTLNYGGIALMWRGGCIIRSVFLGKIKDAFDRNPGLQNLLLDDFFKSAVENCQDSWRRAISTGVQAGIPMPCFTTALSFYDGYRHAMLPANLIQAQRDYFGAHTYELLAKPG-------QFIHTNWTGHGGSVSSSSYNA 482
3 -118.0002jkv_A mol:protein length:505 6-PHOSPHOGLUCONATE DEHYDROGENASE, DECARBOXYLATING  ali model follow..  65  19.QADIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGTKVVGAQSLKEMVSKLKKPRRIILLVKAGQAVDDFIEKLVPLLDTGDIIIDGGNSEYRDTTRRCRDLKAKGILFVGSGVSGGEEGARYGPSLMPGGNKEAWPHIKTIFQGIAAKVTGEPCCDWVGDEGAGHFVKMVHNGIEYGDMQLICEAYHLMKDVLGMAQDEMAQAFEDWNKTELDSFLIEITANILKFQDTDGKHLLPKIRDSAGQKGTGKWTAISALEYGVPVTLIGEAVFARCLSSLKDERIQASKKL-KGPQKFQFDGDKKSFLEDIRKALYASKIISYAQGFMLLRQAATEFGWTLNYGGIALMWRGGCIIRSVFLGKIKDAFDRNPELQNLLLDDFFKSAVENCQDSWRRAVSTGVQAGIPMPCFTTALSFYDGYRHEMLPASLIQAQRDYFGAHTYELLAKPG-------QFIHTNWTGHGGTVSSSSYNA 499
4 -115.0005uq9_A mol:protein length:489 6-phosphogluconate dehydrogenase, decarboxylating  ali model follow..  65  9.QADIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKGTKVVGAQSLKEMVSKLKKPRRIILLVKAGQAVDDFIEKLVPLLDTGDIIIDGGNSEYRDTTRRCRDLKAKGILFVGSGVSGGEEGARYGPSLMPGGNKEAWPHIKTIFQGIAAKVTGEPCCDWVGDEGAGHFVKMVHNGIEYGDMQLICEAYHLMKDVLGMAQDEMAQAFEDWNKTELDSFLIEITANILKFQDTDGKHLLPKIRDSAGQKGTGKWTAISALEYGVPVTLIGEAVFARCLSSLKDERIQASKKL-KGPQKFQFDGDKKSFLEDIRKALYASKIISYAQGFMLLRQAATEFGWTLNYGGIALMWRGGCIIRSVFLGKIKDAFDRNPELQNLLLDDFFKSAVENCQDSWRRAVSTGVQAGIPMPCFTTALSFYDGYRHEMLPASLIQAQRDYFGAHTYELLAKPG-------QFIHTNWTGHGGTVSSSSYNA 489
5 -112.0002zyg_A mol:protein length:480 6-phosphogluconate dehydrogenase, decarboxylating  ali model follow..  46  5.KQQIGVVGMAVMGRNLALNIESRGYTVSVFNRSREKTEEVIAENPGK-KLVPYYTVQEFVESLETPRRILLMVKAGAGTDSAIDSLKPYLDKGDIIIDGGNTFFQDTIRRNRELSAEGFNFIGTGVSGGEEGTLKGPSIMPGGQKEAYELVAPILKQIAAVAEGEPCVTYIGADGAGHYVKMVHNGIEYGDMQLIAEAYALLKGGLALSNEELAQTFTEWNEGELSSYLIDITKDIFTKKDEEGKYLVDVILDEAANKGTGKWTSQSSLDLGEPLSLITESVFARYISSLKDQRVAASKVL--SGPQAQPAGDKAEFIEKVRRALYLGKIVSYAQGFSQLRAASDEYNWDLNYGEIAKIFRAGCIIRAQFLQKITDAYAQNAGIANLLLAPYFKQIADDYQQALRDVVAYAVQNGIPVPTFSAAIAYYDSYRSAVLPANLIQAQRDYFGAHTYKRTDKEGI--------FHTEWLE............ 470
6 -112.0002zya_A mol:protein length:480 6-phosphogluconate dehydrogenase, decarboxylating  ali model follow..  48  5.KQQIGVVGMAVMGRNLALNIESRGYTVSIFNRSREKTEEVIAENPG-KKLVPYYTVKEFVESLETPRRILLMVKAGAGTDAAIDSLKPYLDKGDIIIDGGNTFFQDTIRRNRELSAEGFNFIGTGVSGGEEGALKGPSIMPGGQKEAYELVAPILTKIAAVADGEPCVTYIGADGAGHYVKMVHNGIEYGDMQLIAEAYSLLKGGLNLTNEELAQTFTEWNNGELSSYLIDITKDIFTKKDEDGNYLVDVILDEAANKGTGKWTSQSALDLGEPLSLITESVFARYISSLKDQRVAASKVL--SGPQAQPAGDKAEFIEKVRRALYLGKIVSYAQGFSQLRAASEEYNWDLNYGEIAKIFRAGCIIRAQFLQKITDACAENPQIANLLLAPYFKQIADDYQQALRDVVAYAVQNGIPVPTFSAAVAYYDSYRAAVLPANLIQAQRDYFGAHTYKRIDKEGV--------FHTEWLD............ 470
7 -108.0002iz0_A mol:protein length:474 6-PHOSPHOGLUCONATE DEHYDROGENASE, DECARBOXYLATING  ali model follow..  49  5.QANFGVVGMAVMGKNLALNVESRGYTVAIYNRTTSKTEEVFKEHQD-KNLVFTKTLEEFVGSLEKPRRIMLMVQAGAATDATIKSLLPLLDIGDILIDGGNTHFPDTMRRNAELADSGINFIGTGVSGGEKGALLGPSMMPGGQKEAYDLVAPIFEQIAAKADGKPCVAYMGANGAGHYVKMVHNGIEYGDMQLIAESYDLLKRILGLSNAEIQAIFEEWNEGELDSYLIEITKEVLKRKDDEGEGYIVDKILDKANKGTGKWTSESALDLGVPLPLITESVFARYISTYKDERVKASKVL--SGPALDFSGDKKEVIEKIRKALYFSKIMSYAQGFAQLRKASEEFDWDLPYGTIAQIWRAGCIIRAEFLQNITDAFDKDSELENLLLDDYFVDITKRYQEAVRDVVSLAVQAGTPIPTFTSAISYYDSYRSENLPANLIQAQRDYFGAHTYERTDKAGI--------FHYDWYTED.......... 474
8 -107.0002w90_A mol:protein length:471 6-PHOSPHOGLUCONATE DEHYDROGENASE, DECARBOXYLATING  ali model follow..  46  5.KHQIGVIGLAVMGKNLALNIESKGYSVAVYNRLREKTDEFLQE-AKGKNIVGTYSIEEFVNALEKPRKILLMVKAGAPTDATIEQLKPHLEKGDIVIDGGNTYFKDTQRRNKELAELGIHFIGTGVSGGEEGALKGPSIMPGGQKEAHELVRPIFEAIAAKVDGEPCTTYIGPDGAGHYVKMVHNGIEYGDMQLIAEAYFLLKHVLGMDAAELHEVFADWNKGELNSYLIEITADIFTKIDEETGKPLVDVILDKAGQKGTGKWTSQNALDLGVPLPIITESVFARFLSAMKDERVKASKVLAGPAVKPFEGDRAHFIEAVRRALYMSKICSYAQGFAQMKAASEEYNWNLRYGDIAMIFRGGCIIRAQFLQKIKEAYDRDPALSNLLLDSYFKDIVERYQDALREIVATAAMRGIPVPGSASALAYYDSYRTAVLPANLIQAQRDYFGAHTYERVDKEGI--------FHTEWLK............ 471
9 -105.0006fqx_A mol:protein length:468 6-phosphogluconate dehydrogenase, decarboxylating  ali model follow..  44  1.MCDIGLIGLAVMGQNLSLNISSKGFKIGVYNRTYERTEETMKRAKEENVVYGYKTVEELINNLKKPRKVILLIKAGPAVDENISNILKHFEKGDIIIDGGNEWYINSERRIKLCKEKDVEYLAMGVSGGEAGARYGCSFMPGGSKYAYDCVKEILEKCSAQVGNSPCVTYIGPGSSGNYVKMVHNGIEYGDMQLISESYVIMKHILKYDNQKLSEVFNKWNEGILNSYLIEITANILAKKDDLTNNYLVDMILDIAAKGTGKWTMLEATERGIPCPTMCAALDARNISVFKELRTKAESNFNKDNILIDPNEDLNDFENDLLNALYCCKIISYTQGLFLLKQVSEEMNWKLNLGEIARIWRGGCIIRAVFLDRIANAYKNNEKLELLFLDNEFSDDIKNKLPSLRKIVLMATKYSIPIPAFSASLAYFQMVTSQNLPLNLVQAQRDYFGSHTYRRTDREGN--------YHTLW.............. 468
10 -104.0001pgj_A mol:protein length:478 6-PHOSPHOGLUCONATE DEHYDROGENASE  ali model follow..  33  1.SMDVGVVGLGVMGANLALNIAEKGFKVAVFNRTYSKSEEFMKANASAPNLKAFETMEAFAASLKKPRKALILVQAGAATDSTIEQLKKVFEKGDILVDTGNAHFKDQGRRAQQLEAAGLRFLGMGISGGEEGARKGPAFFPGGTLSVWEEIRPIVEAAAAKADGRPCVTMNGSGGAGSCVKMYHNSGEYAILQIWGEVFDILRAMGLNNDEVAAVLEDWKSKNFLKSYMLDISIAAARAKDKDGSYLTEHVMDRIGSKGTGLWSAQEALEIGVPAPSLNMAVVSRQFTMYKTERQANASNAPSPGYTLKNKSPSGPEIKQLYDSVCIAIISCYAQMFQCLREMDKVHNFGLNLPATIATFRAGCILQGYLLKPMTEAFEKNPNISNLM--CAFQTEIRAGLQNYDMVALITSKLEVSIPVLSASLNYVTAMFTPTLKGQLVSLQRDVFGRHGYERVDKDGR--------ESFQWPELQ.......... 478
11 -68.6004e21_A mol:protein length:358 6-phosphogluconate dehydrogenase (Decarboxylating)  ali model follow..  31  15QSMQIGMIGLGRMGADMVRRLRKGGHECVVYDLNVNAVQALEREGIA-----GARSIEEFCAKLVKPRVVWLMVPA-AVVDSMLQRMTPLLAANDIVIDGGNSHYQDDIRRADQMRAQGITYVDVGTSGGIFGLERGYCLMIGGEKQAVERLDPVFRTLAPGITAELGYLHCGPSGAGHFVKMVHNGIEYGLMAAYAEGLNILHHANAGK----EGQGADAETAPLRNPDFY--------------------------------------------------------------------------------------------------------------------RYDLDLADITEVWRRGSVISSWLLDLSATALLDSPDLQEFQ-------GRVSDSGEGRWTVAAAIDEGVPAHVLSSALYRFSSRGEDDFANRLLSAMRYEFGGHREKS................................. 352
12 -60.7001vpd_A mol:protein length:299 TARTRONATE SEMIALDEHYDE REDUCTASE  ali model follow..  18  4MTMKVGFIGLGIMGKPMSKNLLKAGYSLVVSDRNPEAIADVIAAGAE-----TASTAKAIAEQCDVIITMLPNSPHVKEVALGENGIIEGAKPGTVLIDMSSIAPLASREISDALKAKGVEMLDAPVSGGEPKAIDGLSVMVGGDKAIFDKYYDLMKAMAGS------VVHTGDIGAGNVTKLANQVIVALNIAAMSEALTLATKAGVNP----DLVYQAIRGGLAGSTVLDAKAPMVMDRNFKPGFRIDLHIKDLANALDTSHGVGAQLPLTAAVMEMMQALRADGHGNDDHSALA................................................................................................................................................................................................ 286
13 -60.6003w6u_A mol:protein length:306 6-phosphogluconate dehydrogenase, NAD-binding protein  ali model follow..  21  14.HMRVGFIGLGIMGGPMATHLLKAGFLAAVYNRTREKTKPFAEAGVY-----VAESPADLAKRVDVVIVMVSDAPDVEQVLFGPSGVVEGARPGLIVVDMSTNSPDWARKFAERLAQYGIEFLDAPVTGGQKGAIEGLTIMVGGKEELFHRLLPIFKAMGRD------IVYMGPVGYGQAMKLVNQVVVALNTVAMVEGLKLAKALGLDM----DKVAEVLTRGAARSGAIELYLPKLLKGDLSPGFKAEHLKKDLGYVLEEARKRGVKLPGAELAYELYRKMVEDGAGSLGIHALG................................................................................................................................................................................................ 295
14 -59.6003pef_A mol:protein length:287 6-phosphogluconate dehydrogenase, NAD-binding  ali model follow..  17  1.SQKFGFIGLGIMGSAMAKNLVKAGCSVTIWNRSPEKAEELAALGAE-----RAATPCEVVESCPVTFAMLADPAAAEEVCFGKHGVLEGIGEGRGYVDMSTVDPATSQRIGVAVVAKGGRFLEAPVSGSKKPAEDGLIILAAGDRNLYDEAMPGFEKMGKK------IIHLGDVGKGAEMKLVVNMVMGGMMACFCEGLALGEKAGLAT----DAILDVIGAGAMANPMFALKGGLIRDRNFAPAFPLKHMQKDLRLAVALGDRVGQPLVASAAANELFKGARAAGFGDEDFSAIF................................................................................................................................................................................................ 282
15 -59.1003pdu_A mol:protein length:287 3-hydroxyisobutyrate dehydrogenase family protein  ali model follow..  17  1.MTTYGFLGLGIMGGPMAANLVRAGFDVTVWNRNPAKCAPLVALGAR-----QASSPAEVCAACDITIAMLADPAAAREVCFGANGVLEGIGGGRGYIDMSTVDDETSTAIGAAVTARGGRFLEAPVSGTKKPAEDGLIILAAGDQSLFTDAGPAFAALGKK------CLHLGEVGQGARMKLVVNMIMGQMMTALGEGMALGRNCGLDG----GQLLEVLDAGAMANPMFKGKGQMLLSGEFPTSFPLKHMQKDLRLAVELGDRLGQPLHGAATANESFKRARAAGHADEDFAAVF................................................................................................................................................................................................ 282
16 -58.9001yb4_A mol:protein length:295 tartronic semialdehyde reductase  ali model follow..  17  3.AMKLGFIGLGIMGSPMAINLARAGHQLHVTTIGP-VADELLSLGAV-----NVETARQVTEFADIIFIMVPDTPQVEDVLFGEHGCAKTSLQGKTIVDMSSISPIETKRFAQRVNEMGADYLDAPVSGGEIGAREGLSIMVGGEQKVFDRVKPLFDILGKN------ITLVGGNGDGQTCKVANQIIVALNIEAVSEALVFASKAGADP----VRVRQALMGGFASSRILEVHGERMINRTFEPGFKIALHQKDLNLALQSAKALALNLPNTATCQELFNTCAANGGSQLDHSAMV................................................................................................................................................................................................ 283
17 -58.8004dll_A mol:protein length:320 2-hydroxy-3-oxopropionate reductase  ali model follow..  14  24YARKITFLGTGSMGLPMARRLCEAGYALQVWNRTPARAASLAALGAT-----IHEQARAAARDADIVVSMLENGAVVQDVLFA-QGVAAAMKPGSLFLDMASITPREARDHAARLGALGIAHLDTPVSGGTVGAEQGLVIMAGGKPADFERSLPLLKVFGR-------ATHVGPHGSGQLTKLANQMIVGITIGAVAEALLFATKGGADM----AKVKEAITGGFADSRVLQLHGQRMVERDFAPRARLSIQLKDMRNALATAQEIGFDAPITGLFEQLYAEGVEHGLTDLDQSGLF................................................................................................................................................................................................ 304
18 -58.3003obb_A mol:protein length:300 Probable 3-hydroxyisobutyrate dehydrogenase  ali model follow..  16  2HMKQIAFIGLGHMGAPMATNLLKAGYLLNVFDLVQSAVDGLVAAGAS-----AARSARDAVQGADVVISMLPASQHVEGLYLDDDGLLAHIAPGTLVLECSTIAPTSARKIHAAARERGLAMLDAPVSGGTAGAAAGLTFMVGGDAEALEKARPLFEAMGRN------IFHAGPDGAGQVAKVCNNQLLAVLMIGTAEAMALGVANGLEA----KVLAEIMRRSSGGNWALEVYNPWPASRDYSGGFMAQLMAKDLGLAQEAAQASASSTPMGSLALSLYRLLLKQGYAERDFSVVQ................................................................................................................................................................................................ 291
19 -58.3003doj_A mol:protein length:310 Dehydrogenase-like protein  ali model follow..  17  15.MMEVGFLGLGIMGKAMSMNLLKNGFKVTVWNRTLSKCDELVEHGAS-----VCESPAEVIKKCKYTIAMLSDPCAALSVVFDKGGVLEQICEGKGYIDMSTVDAETSLKINEAITGKGGRFVEGPVSGSKKPAEDGLIILAAGDKALFEESIPAFDVLGKR------SFYLGQVGNGAKMKLIVNMIMGSMMNAFSEGLVLADKSGLSS----DTLLDILDLGAMTNPMFKGKGPSMNKSSYPPAFPLKHQQKDMRLALALGDENAVSMPVAAAANEAFKKARSLGLGDLDFSAVI................................................................................................................................................................................................ 296
20 -58.3002uyy_A mol:protein length:316 N-PAC PROTEIN  ali model follow..  15  24.DKKIGFLGLGLMGSGIVSNLLKMGHTVTVWNRTAEKCDLFIQEGAR-----LGRTPAEVVSTCDITFACVSDPKAAKDLVLGPSGVLQGIRPGKCYVDMSTVDADTVTELAQVIVSRGGRFLEAPVSGNQQLSNDGLVILAAGDRGLYEDCSSCFQAMGKT------SFFLGEVGNAAKMMLIVNMVQGSFMATIAEGLTLAQVTGQSQ----QTLLDILNQGQLASIFLDQKCQNILQGNFKPDFYLKYIQKDLRLAIALGDAVNHPTPMAAAANEVYKRAKALDQSDNDMSAVY................................................................................................................................................................................................ 305
21 -58.1005u5g_A mol:protein length:295 6-phosphogluconate dehydrogenase  ali model follow..  16  1MNRVVGFIGLGRMGQAICRRLLASQMPVHVHNRSREKADDLIRQGAV-----WAPDIVALTRAARVLFVCTAGSEAVQDFYHAPDGLLACLEVGDIVVDLSTIAPETAEGLHAAFAQQGADYIECPVSGGVEGALAGLSAIVSGRPEAYGLIRPLLEVFCAT------VTYVPEPGKAQRLKILNNLAESINLAGAIEVISQGLSQGLDL----KSMADVFTSCRGRSAYMDVALGYALSGGASSNVSLGVRCKDLELARRRL-PQDQSYPFSTLAMTTFDTVRQACGEESDQCQYF................................................................................................................................................................................................ 283
22 -58.1003cky_A mol:protein length:301 2-hydroxymethyl glutarate dehydrogenase  ali model follow..  21  4.SIKIGFIGLGAMGKPMAINLLKEGVTVYAFDLMEANVAAVVAQGAQ-----ACENNQKVAAASDIIFTSLPNAGIVETVMNGPGGVLSACKAGTVIVDMSSVSPSSTLKMAKVAAEKGIDYVDAPVSGGTKGAEAGLTIMVGASEAVFEKIQPVLSVIGKD------IYHVGDTGAGDAVKIVNNLLLGCNMASLAEALVLGVKCGLKP----ETMQEIIGKSSGRSYAMEAKMEFIMSGDFAGGFAMDLQHKDLGLALEAGKEGNVPLPMTAMATQIFEGGRAMGLGREDMSAVI................................................................................................................................................................................................ 286
23 -57.9002i9p_A mol:protein length:319 3-hydroxyisobutyrate dehydrogenase  ali model follow..  19  15QSMPVGFIGLGNMGNPMAKNLMKHGYPLIIYDVFPDACKEFQDAGEQ-----VVSSPADVAEKADRIITMLPTSINAIEAYSGANGILKKVKKGSLLIDSSTIDPAVSKELAKEVEKMGAVFMDAPVSGGVGAARSGLTFMVGGVEDEFAAAQELLGCMGSN------VVYCGAVGTGQAAKICNNMLLAISMIGTAEAMNLGIRLGLDP----KLLAKILNMSSGRCWSSDTYNPVPSANNYQGGFGTTLMAKDLGLAQDSATSTKSPILLGSLAHQIYRMMCAKGYSKKDFSSVF................................................................................................................................................................................................ 304
24 -57.0005je8_A mol:protein length:302 3-hydroxyisobutyrate dehydrogenase  ali model follow..  16  7.MKKIGFIGLGNMGLPMSKNLVKSGYTVYGVDLNKEAEASFEKEGGI-----IGLSISKLAETCDVVFTSLPSPRAVEAVYFGAEGLFENGHSNVVFIDTSTVSPQLNKQLEEAAKEKKVDFLAAPVSGGVIGAENRLTFMVGGSKDVYEKTESIMGVLGAN------IFHVSEQDSGTTVKLINNLLIGFYTAGVSEALTLAKKNNMDL----DKMFDILNVSYGQSRIYERNYKFIAPENYEPGFTVNLLKKDLGFAVDLAKESELHLPVSEMLLNVYDEASQAGYGENDMAALY................................................................................................................................................................................................ 290
25 -56.9003g0o_A mol:protein length:303 3-hydroxyisobutyrate dehydrogenase  ali model follow..  16  7.DFHVGIVGLGSMGMGAARSCLRAGLSTWGADLNPQACANLLAEGA----CGAAASAREFAGVVDALVILVVNAAQVRQVLFGEDGVAHLMKPGSAVMVSSTISSADAQEIAAALTALNLNMLDAPVSGGAVKAAQGMTVMASGSEAAFTRLKPVLDAVASN------VYRISDTGAGSTVKIIHQLLAGVHIAAAAEAMALAARAGIPL----DVMYDVVTHAAGNSWMFENRMQHVVDGDYTPRSAVDIFVKDLGLVADTAKALRFPLPLASTALNMFTSASNAGYGKEDDSAVI................................................................................................................................................................................................ 290
26 -55.3005y8g_A mol:protein length:295 Probable 3-hydroxyisobutyrate dehydrogenase  ali model follow..  16  1MMTTIAFLGLGNMGAPMSANLVGAGHVVRGFDPAPTAASGAAAHGVA-----VFRSAPEAVAEADVVITMLPTGEVVRRC---YTDVLAAARPATLFIDSSTISVTDAREVHALAESHGMLQLDAPVSGGVKGAAAALAFMVGGDESTLRRARPVLEPMAGK------IIHCGAAGAGQAAKVCNNMVLAVQQIAIAEAFVLAEKLGLSA----QSLFDVITGATGNCWAVHTNCPVPANNDFKPGFSTALMNKDLGLAMDAVAATGATAPLGSHAADIYAKFAA............................................................................................................................................................................................................ 275
27 -54.5003qha_A mol:protein length:296 Putative oxidoreductase  ali model follow..  17  15.QLKLGYIGLGNMGAPMATRMTEWPGGVTVYDIRIEAMTPLAEAGAT-----LADSVADVAAA-----LIHITVLDDAQVREVVGELAGHAKPGTVIAIHSTISDTTAVELARDLKARDIHIVDAPVSGGAAAAARGLATMVGADREVYERIKPAFKHWAAV------VIHAGEPGAGTRMKLARNMLTFTSYAAACEAMKLAEAAGLDL----QALGRVVRHTDALTGGPGAIMVRDNMKDLEPLHTRGLGEKDLSLALALGEAVSVDLPLARLAYEGLAAGLGVPHKEKE..................................................................................................................................................................................................... 295
28 -53.3004gbj_A mol:protein length:297 6-phosphogluconate dehydrogenase NAD-binding  ali model follow..  14  4MSEKIAFLGLGNLGTPIAEILLEAGYELVVWNRTASKAEPLTKLGAT-----VVENAIDAITPGGIVFSVLADDAAVEELFSM--ELVEKLGKDGVHVSMSTISPETSRQLAQVHEWYGAHYVGAPIFARPEAVRAKGNICLSGNAGAKERIKPIVENFVKG------VFDFGDDGAANVIKLAGNFMIACSLEMMGEAFTMAEKNGISR----QSIYEMLTSTLFAAPIFQNYGKLVASNTYEPAFRFPLGLKDINLTLQTASDVNAPMPFADIIRNRFISGLAKGRENLDWGALA................................................................................................................................................................................................ 286
29 -51.6001wp4_A mol:protein length:289 3-hydroxyisobutyrate dehydrogenase  ali model follow..  18  1.MEKVAFIGLGAMGYPMAGHLARRFPTLVWNRTFEKALRHQEEFGS-------EAVPLERVAEARVIFTCLPTTREVYEV---AEALYPYLREGTYWVDATSGEPEASRRLAERLREKGVTYLDAPVSGGTSGAEAGLTVMLGGPEEAVERVRPFLA-YAKK------VVHVGPVGAGHAVKAINNALLAVNLWAAGEGLLALVKQGVSA----EKALEVINASSGRSNATENLPQRVLTRAFPKTFALGLLVKDLGIAMGVLDGEKAPSPLLRLAREVYEMAKRELGPDADHVEAL................................................................................................................................................................................................ 277
30 -47.9004oqz_A mol:protein length:289 Putative oxidoreductase YfjR  ali model follow..  15  1MSQSVTVIGLGPMGQAMAAAYLDRGYEVTLWNRTASRADALVARGAK-----LAATPEQALSANELVILSLIDYDAMYGVLEGAEEAV----AGRVLVNLSSDTPEKARAAARRVAELGGTHLTGGVLSPPPGIGSPMSTFYSGPRAAYDQHRAALEVITGK------TDYRGEDGLAALMYQLNMVVFWPAMLSYWQAVALADAHGLTAADIAPYVSENFAG---MGQFIDFYAARIDAGNHAGDDRLSMGVASMEHVVHTNADSGVDTAFPRAVLDAFHRGADAGFGADSFSSVI................................................................................................................................................................................................ 282
31 -47.7004d3s_A mol:protein length:293 IMINE REDUCTASE  ali model follow..  14  8.KSPVTLIGLGPMGQAMAGALLEAGYELTVWNRTKAKAEALAERGAA-----VADSPAEALRAGGPVLLSLTEHAVMYRVLEGAESDL----KGRTILNLGSDTPAASRAAAAWAEGHGARYVTGGVMSPAPGIGSSVFSFYSGDRAAFEENKALLEVLTAT------DFRGEDPGLAQVYYQILLDLFWTTMTGYLHALAVARAEGVPV----GTITPYLIEGNDMAMFFEGTSAAVAEGRFGDEDRISMDAASMEHVVQTSRDAGVDTALPEAVLSLFRRGLDAGFAESSFARLV................................................................................................................................................................................................ 286
32 -47.0005a9r_A mol:protein length:290 IMINE REDUCTASE  ali model follow..  12  5.NLPVTVAGLGPMGSALAAALLDRGHDVTVWNRSPGKAAPLVAKGAR-----QADDIVDAVSASRLLVVCLADYDALYSALGPAREAL----RGRVVVNLNSGTPKEANEALRWAERHGTGYLDGAIMVPPAMVGHPSVFLYSGSAEVFEEYKETLAGLGDP------VHLGTEAGLAVLYNTALLSMMYSSMNGFLHAAALVGSAGVPAAEFTKLAVDWFLPAVIGQIIKAEAPTIDEGVYPGDAGSLEMNVTTLKHIIGTSQEQGVDTEIPVRNKELLDRAVAAGFGESSYYSVI................................................................................................................................................................................................ 286
33 -46.6004oqy_A mol:protein length:290 (S)-imine reductase  ali model follow..  15  3.KQSVTVIGLGPMGQAMVNTFLDNGHEVTVWNRTASKAEALVARGAV-----LAPTVEDALSANELIVLSLTDYDAVYAILEPVTGSL----SGKVIANLSSDTPDKAREAAKWAAKHGAKHLTGGVQVPPPLIGKPSSTYYSGPKDVFDAHEDTLKVLTNA------DYRGEDAGLAAMYYQAQMTIFWTTMLSYYQTLALGQANGVSAKELLPYA----MMTSMMPHFLELYAQHVDSADYPGDVDLAMGAASVDHVLHTHQDAGVSTVLPAAVAEIFKAGMEKGFAENSFSSLI................................................................................................................................................................................................ 282
34 -46.5005ocm_A mol:protein length:291 NAD_Gly3P_dh, NAD-dependent glycerol-3-phosphate dehydrogenase  ali model follow..  13  3.DTDVTVLGLGLMGQALAGAFLKDGHATTVWNRSEGKAGQLAEQGAV-----LASSARDAAEASPLVVVCVSDHAAVRAVLDPLGDVL----AGRVLVNLTSGTSEQARATAEWAAERGITYLDGAIMAIPQVVGTAAFLLYSGPEAAYEAHEPTLRSLGAG------TTYLGDHGLSSLYDVALLGIMWGTLNSFLHGAALLGTAKVEATTFAPFA----RWIEAVTGFVSAYAGQVDQGAYPLDATIDTHVATVDHLIHESEAAGVNTELPRLVRTLADRALAGGQGGLGYAAMI................................................................................................................................................................................................ 283
35 -46.1003zgy_A mol:protein length:309 R-IMINE REDUCTASE  ali model follow..  10  18EHTPVTVIGLGLMGQALAGAFLGAGHPTTVWNRTAAKAEPLVARGAK-----SAGSVAEAVAASPLVVVCVSDYDAVHAL---LDPLDGTALQGRTLVNLTSGTSAQARERAAWADGRGADYLDGAILAGPAAIGTAAVVLLSGPRSAFDPHASALGGLGAG------TTYLGADGLASLYDAAGLVMMWSILNGFLQGAALLGTAGVDATTFAPFITQGIGTVAD---WLPGYARQIDDGAYPDDAAIDTHLATMEHLIHESEFLGVNAELPRFIKALADRAVADGHGGSGYPALI................................................................................................................................................................................................ 300
36 -46.1004d3d_A mol:protein length:310 IMINE REDUCTASE  ali model follow..  13  21.RKSVTVIGLGPMGQAMADVFLEYGYSVTVWNRTSSKADQLVAKGAI-----RVSTVNEALAANELVILSLTDYNVMYSIL----EPVSENLFGKVLVNLSSDTPEKARKAAKWLEDRGARHITGGVQVPPSGIGKSSYTYYSGDRVVFEAHRETLEVLTSS------DYRGEDPGLAMLYYQIQMDIFWTAMLSYLHALAIANANGITAEQFLPYASAMMSSLPK---FVEFYTPRLDEGEHPGDVDLAMGLASVEHVVHTTQEAGIDIALPATVLEVFRRGMKTGHASDSFTSLI................................................................................................................................................................................................ 300
37 -46.0005g6r_A mol:protein length:295 IMINE REDUCTASE  ali model follow..  12  1MSKHIGIFGLGAMGTALAAKYLEHGYKTSVWNRTTAKAIPLVEQGAK-----LASTISEGVNANDLIIICLLNNQVVEDALRDALQTL----PSKTIVNLTNGTPNQARKLADFVTSHGARYIHGGIMAVPTMIGSPAVLLYSGESLEFQSIESHLSLLGMS------KYLGTDAGSASLHDLALLSGMYGLFSGFLHAVALIKSGQDTSTTATGLLPLLTPWLSAMTGYLSSIAKQIDDGDYATGSNLGMQLAGVENIIRAGEEQRVSSQMILPIKALIEQAVGEGHGGEDLSALI................................................................................................................................................................................................ 285
38 -45.9003l6d_A mol:protein length:306 Putative oxidoreductase  ali model follow..  14  8FEFDVSVIGLGAMGTIMAQVLLKQGKRVAIWNRSPGKAAALVAAGAH-----LCESVKAALSASPATIFVLLDNHATHEV-LGMPGVARAL-AHRTIVDYTTNAQDEGLALQGLVNQAGGHYVKGMIVAYPRNVGHRSHSIHTGDREAFEQHRALLEGLAGH------TVFLPW-DEALAFATVLHAHAFAAMVTFFEAVGAGDRFGLPVSKTARLLLE--TSRFFVADALEEAVRRLETQDFKDQARLDVHADAFAHIAQSLHAQGVWTPVFDAVCQVVQRAAAMGYGDQDIAATT................................................................................................................................................................................................ 290
39 -42.9005ojl_A mol:protein length:298 Imine reductase  ali model follow..  13  7.TTKLTIFGLGAMGTAMATQFLKQGHTPTVWNRTAAKANPLVEQGAH-----LAATIPAAIAASPLLIFCLLDNAAVEQTLAAGPPSL----AGKTILNLTNGTPSQARRLATLASARGARYFHGGIMADMIGAPHAILYSGGGSAETYASVEGVLAVLGSG------KYLGDDAGSASLHDLALLSGMYGLFAGFATALVRSEGEGVSATEFLGLLAPWLQ---AMTGYLGLLARQIDDGVYTATSNLEMQLVALENACAASREQGVSAEVMLPLKGLVERAVREGRGGHDISSLI................................................................................................................................................................................................ 290
40 -33.0001i36_A mol:protein length:264 CONSERVED HYPOTHETICAL PROTEIN MTH1747  ali model follow..  12  1..LRVGFIGFGEVAQTLASRLRSRGVEVVTSLEGRSPSTIERARTVG-----VTETSEEDVYSCPVVISAVTPGVALGAARRAGRHV------RGIYVDINNISPETVRMASSLIEKGG--FVDAAIMGSVRRKGADRIIASGRDAEEFMKLNRYGLNI---------EVRGREPGDASAIKMLRSSYTKGVSALLWETLTAAHRLGLE-----EDVLEMLEYTEGND--FRESAISRLKSSCIHAR---RRYEEMKEVQDMLAEVIDPVMPTCIIRIFDKLKDVKVSADARLQGCA................................................................................................................................................................................................ 264
41 -32.0004ezb_A mol:protein length:317 uncharacterized conserved protein  ali model follow..  10  17MMTTIAFIGFGEAAQSIAGGLGGRNAALAAYDASGALRARAAELGVE------PLDDVAGIACADVVLSLVVGAATKAVA----ASAAPHLSDEAVFIDLNSVGPDTKALAAGAIATGKGSFVEGAVMARVPPYAEKVPILVAGRRA--VEVAERLNALGMNLE--------ETPGQASSLKMIRSVMIKGVEALLIEALSSAERAGVTE-RILDSVQETFPGLDWRDVADYYLSRTFEHG---------RRVTEMTEAAETIESFGLNAPMSRAACETIAAAHAAMKDQGLSVN.................................................................................................................................................................................................. 293
42 -29.1003qsg_A mol:protein length:312 NAD-binding phosphogluconate dehydrogenase-like protein  ali model follow..  11  18.AMKLGFIGFGEAASAIASGLRQAGADMAAYDAASAES---WRPRAEELGVSCKASVAEVAGECDVIFSLVTAQAALEVA----QQAGPHLCEGALYADFTSCSPAVKRAIGDVISRHRPSAQYAAVAVMSAVKPHGRVPLVVDGDGARRFQAAFTLYGCR------IEVLDGEVGGAALLKMCRSAVLKGLEALFLEALAAAEKMGLAD-RVLASLDASFPEHHLRDLALYLVERNLEHA---------RRAHELGEVAATLCSVGVEPLVAEAGYRRLTRVAQVRAALKQRPGDV................................................................................................................................................................................................ 293
43 -27.1004ypo_A mol:protein length:333 Ketol-acid reductoisomerase  ali model follow..  12  14.GRKVGVIGYGSQGHAHSLSLRDSGVQVRVGLKQGSRSRPKVEEQG-----LDVDTPAEVAKWADV---VMVLAPDTAQAEIFAGDIEPNLKPGDALFFGHGLNVHFGLIKPPADVAVAMVAPKGPGHLVRRQFVDGVAVEQDPRGDGLALALSYAKAIGGT------RAGVIKTTFKDETETEQTVLCGGTEELVKAGFEVMVEAGYPAELAYFEVLHELK........................................................................................................................................................................................................................................................................... 230
44 -24.4004xiy_A mol:protein length:338 Ketol-acid reductoisomerase  ali model follow..  13  16.SKKVAIIGYGSQGHAHACNLKDSGVDVYVGLRAGSASVAKAEAHG-----LTVKSVKDAVAAADV---VMILTPDEFQGRLYKDEIEPNLKKGATLAFAHGFSIHYNQVVPRADLDVIMIAPKAPGHTVRSEFVRGGGILIAVYQDASGNAKNLALSYACGVGRTGIIETTFKDETETDLFGEQAVLCGGCVELVKAGFETLVEAGYAPEMAYFECLHELK........................................................................................................................................................................................................................................................................... 232
45 -22.7004kqw_A mol:protein length:350 Ketol-acid reductoisomerase  ali model follow..  12  28..LKVGIIGYGSQGHAHALNLMDSGVDVRVGLREGSSSWKTAEEAG-----LKVTDMDTAAEEADV---IMVLVPDEIQPKVYQEHIAAHLKAGNTLAFAHGFNIHYGYIVPPEDVNVIMCAPKGPGHIVRRQFTEGACVQQDATGNAWDIVLSYCWGVGGARSGIIKATF--AEETEEDLFGEQAVLCGGLVELVKAGFETLTEAGYPPELAYFECYHEMK........................................................................................................................................................................................................................................................................... 243
46 -22.5002yjz_A mol:protein length:201 METALLOREDUCTASE STEAP4  ali model follow..  10  18KQGVVCIFGTGDFGKSLGLKMLQCGYSVVFGSRNPQVSSLLPRGAE-------VLCYSEAASRSDVIVLAVHREHYDFLAELADS-------KGRVLIDVSNYPESNAEYLAQLVPGKAFNTISAWALQSGTLDASRQVFVCGNDSKAKDRVMDIARTLGLT------PLDQGSLVAAKEIE................................................................................................................................................................................................................................................................................................................... 190
47 -22.4001np3_A mol:protein length:338 Ketol-acid reductoisomerase  ali model follow..  11  17..KKVAIIGYGSQGHAHACNLKDSGVDVTVGLRSGSATVAKAEAHG-----LKVADVKTAVAAADV---VMILTPDEFQGRLYKEEIEPNLKKGATLAFAHGFSIHYNQVVPRADLDVIMIAPKAPGHTVRSEFVKGIAIYQDASGNAKNVALSYACGVGGGRTG--IIETTFKDETETDLFGEQAVLCGGCVELVKAGFETLVEAGYAPEMAYFECLHELK........................................................................................................................................................................................................................................................................... 232
48 -22.3005t57_A mol:protein length:296 Semialdehyde dehydrogenase NAD-binding protein  ali model follow..  13  15MKEKIALFGAGKMGVRLAKNLLKSDYRVSHVEVSEVGKKRLKDELG-----LECVSTEAALDNVDVVILAVPD----TIIGKIAAQIAPQLRPGTMVMTLDAAAPFAGHLPDRPDLTYFVAHPCHPLIFNDETDPEATSALMQGPEEAFDLGEAVAKVIYAPILR---SYRLTVDQMALLEPGLSETICATLLQVMREAMDETVRRGVPKEAARDFLLGHMNI.......................................................................................................................................................................................................................................................................... 240
49 -22.1004yte_A mol:protein length:194 H(2)-forming methylenetetrahydromethanopterin dehydrogenase-related protein MJ0715  ali model follow..  11  19..KVPEKFGGEPPYGGMAIEFAKAGHDVVLSEPNRDVMSDDLWKKVEDAGVKVVSDDIEAAKHGEI---HVLFTPFGRITLNIANTIIEHVPENAIICNTCTIPTPVLYRSLEGILRRDVGISSMHPTGVPGTPSQKYYTIAGATEDQINKLVELVKSVGKIP...................................................................................................................................................................................................................................................................................................................................... 189
50 -21.3004yt4_A mol:protein length:375 H(2)-forming methylenetetrahydromethanopterin dehydrogenase-related protein MJ1338  ali model follow..  10  12..MKVSVYGAGNQGSRMAIEFAEAGHDVVLAEPNKNIMSDDLWKKVEDAGVKVVSDDVEAAKHGEI---HVLFTPFGKATFRIAKTIIEHVPENAVICNTCTVSPVVLYYSLEPILRKDVGISSMHPAAVPGTPQHGHYVIGGKTEEQIKKAVELAKSAGKE------AYVVPADVSSVVADMG-SLVTAVALSGVLDYYTVGRKIINAPKKMIEQQVI.............................................................................................................................................................................................................................................................................. 249
51 -20.9005yeq_A mol:protein length:340 Ketol-acid reductoisomerase (NADP(+))  ali model follow..  12  18..KRVAVLGYGSQGRAWALNLRDSGIKVSVGLEREGNSWKQAENDG-----FKPLRTEEAVRNSDI---IIFLLPDMIQRTVYLERVKPYLKEGMDLVFAHGFNIHYRLIEPPSNVDVYMIAPKAPGPIVREYFAKGVATYQDHSGKALQKALAVAKAIGAT------RAGVIETTFKEETETEQVDLVGGVMQLMRYAFQTLVEAGYQPEVAYFETINEMK........................................................................................................................................................................................................................................................................... 233
52 -20.6002vns_A mol:protein length:215 METALLOREDUCTASE STEAP3  ali model follow..  12  28.APKVGILGSGDFARSLATRLVGSGFKVVVGSRNPKRTARLFPSAAQ------VTFQEEAVSSPEVIFVAVFREHYSSLCSLSDQ-------AGKILVDVSNPTEQEHLQHRESNAEKAFNVISAWTLQAGPRDGNRQVPICGDQPEAKRAVSEMALAMGFMP------VDMGSLASAWEVEAMPLRLL............................................................................................................................................................................................................................................................................................................ 209
53 -19.6005e4r_A mol:protein length:490 Ketol-acid reductoisomerase  ali model follow..  11  18..KTIAILGYGSQGRAWALNLRDSGLNVVVGLERQGDSWRRAIDDG-----FKPMYTKDAVAIADI---IVFLVPDMVQKSLWLNSVKDFMKKGADLVFAHGFNIHFKIIEPPKDSDVYMIAPKSPGPIVRRSYEMGVAVYQNVSGEALQKALAIAKGIGCA------RAGVIESTFKEETETEQVILVGGIMELIKASFETLVEEGYQPEVAYFETVNELKLEKGLTGMLRAVSDTAKYGGITVGKFIDKMKIVLERIRSGEFAREWIKEYERGMPTVFKE-----LSELEGSTIETVGRKLREMMFRGMKQISSHETDLFEQVILVGGIMELIKSFETLVEEGYQ-------PEVA----------------YFETVNELKLIVDLIYEKGLTGMLRAVSDTAKYGGITVGKFIIDKSVRDKMKIVLERIRSGEFAREWVFKELSELEGSTIETVGRK............................. 467
54 -18.1003c24_A mol:protein length:286 Putative oxidoreductase  ali model follow..  10  12..KTVAILGAGKMGARITRKIHDSAHHLAAIEIAPEGRDRLQGMGIP------LTDGDGWIDEADVVVLALPD----NIIEKVAEDIVPRVRPGTIVLILDAAAPYAGVMPE---RADITYFIGHPCHPPLFNDETDVCALMQGPEEHYAIGADICETMWSPVTRTHRVTT---EQLAILEPGLSEMVAMPFVETMVHAVDECADRYGIDRQAALDFMI.............................................................................................................................................................................................................................................................................. 229
55 -18.0004xdz_A mol:protein length:343 Ketol-acid reductoisomerase  ali model follow..  15  18..KTIAILGYGSQGRAWALNLRDSGLNVVVGLERQGDSWRRAIDDG-----FKPMYTKDAVAIADI---IVFLVPDMVQKSLWLNSVKDFMKKGADLVFAHGFNPKDSDVYMIAPKSPGPIVRRSYEMGG--GVPALVAVYQNVSGEALQKALAIAKGIGCA------RAGVIESTFKEETETEQVILVGGIMELIKASFETLVEEGYQPEVAYFETVNELK........................................................................................................................................................................................................................................................................... 233
56 -17.0004xdy_A mol:protein length:338 Ketol-acid reductoisomerase  ali model follow..  10  17..KTIAVMGYGAQGDAQANCLKDSGINVVIGETEILGGNKNPSWEKAKEDGFEVLPIDKAAEKGDV---VHILLPDEVQPAIYENQIKPQLKAGKALCFSHGFNICFKRIVPPEDVDVIMVAPKAPGTEERKAYLEGVAVKQNPSGEAREVALAMTKAMHWT------KAGILECTFEQETYEEQCVLCGGLVELMRNGFEVLVEAGYPPEMAYFECVHEMK........................................................................................................................................................................................................................................................................... 237
57 -16.1001jax_A mol:protein length:212 conserved hypothetical protein  ali model follow..  15  1..MRVALLGTGNLGKGLALRLATLGHEIVVGSRREEKAEAKAAERIAGDASITGMKNEDAAEACDIAVLTIPWEHAIDTARDLKNIL-----REKIVVSPLVSERSAAEIVAEVLESSALHTIPAARFANLDEKFDWDVPVCGDDDESKKVVMSLISEIDG-------PLDAGPLSNSRLVE................................................................................................................................................................................................................................................................................................................... 189
58 -15.5005n2i_A mol:protein length:232 Reduced coenzyme F420:NADP oxidoreductase  ali model follow..  14  19.GLSIAVLGTGDQGRGLARRFAMAGHEVILGSRSAERAQAVAAELGEGLPVRGM-DNAGAAEAGDVVIVAVPWDGHRALLESLKDVL-----AGKIVVDCVNEEGSAAEQAAAILPDAAFHHVSAVLLLDPEVEKVDLDVVLGDDREATDVVRALAARIPG-------GVYGGRLRNAHQVE................................................................................................................................................................................................................................................................................................................... 208
59 -15.5004tsk_A mol:protein length:350 Ketol-acid reductoisomerase  ali model follow..  14  18..KRIAVIGYGSQGHAHAQNLRDSGFDVVIGLRPGSSWAKAEADGFR------VMAVGEAVEESDVIMILLPDERQPAVYE---REIRPYLTAGKALAFAHGFNIHFSQIQPPK-KGPGHLVRRVYEAGG--GVPALIAVHQDASGQAKDLALAYARGIGAGRAGILTTTFREETETDLFGEQ--AVLCGGLSALIKAGFETLVEAGYQPEIAYFECLHEMK........................................................................................................................................................................................................................................................................... 232
60 -15.1003dtt_A mol:protein length:245 NADP oxidoreductase  ali model follow..  12  13.GMKIAVLGTGTVGRTMAGALADLGHEVTIGTRDPKATLARAEPDAMGAPPVHLAAFADVAAGAE----LVVNATEGASSIAALTAAGAENLAGKILVDIANNTDSLGEQIQRTFPEKTLNTMNASLDPGRAAGGDHSVFVSGNDAAAKAEVATLLKSLGHQD-----VIDLGDITTARGAE................................................................................................................................................................................................................................................................................................................... 215
61 -14.9005t95_A mol:protein length:271 Prephenate dehydrogenase 1  ali model follow..  12  9.SLKIGIVGFGNFGQFLAKTMIKQGHTLTATSRSDY-----SELCLQMGIHFFRDVSAFLTADIDV---IVLCTSILSLSEVVGSMPLTSLKRPTLFVDVLSVKEHPRELLLREL-PEDSDILCTPMFGPQTAKNTDHTFMYIRDEVICSNFIQIFATEGCKMVQMSCEEH-------AKSQFITHTIGRTLGEMDIQSTPIDTKGFETLVKLKETTMRD............................................................................................................................................................................................................................................................................. 222
62 -14.8002y0c_A mol:protein length:478 UDP-GLUCOSE DEHYDROGENASE  ali model follow..  15  2.SMNLTIIGSGSVGLVTGACLADIGHDVFCLDVDQAKIKEVIARNRSAGRLRFSTDIEAAVAHGDVQFIAVGTPADLQYVLAAARNIGRYMTGFKVIVDKSTVPVGTAERVRAAVAEELAKRQMFSVVSNPEFLKEGAAIVIGCDDVPGERARELMKKLYAPFNRNHERTLYMDVRSAEFTKYAANAMLATRISFMNELANLADRFGADIEAVRRDVEALIRTADEHGQSLQILKAVSSVNATQKRVLADKIVARFGEDLTGRTFAIWGLAFKPNTDDMREAPSRELIAELRGARIAAYDPVAQEEARRVIALDLADHPSWLERLSFVDDEAQAARDADALVIVTEWKIFSPDFVALGRLWKTPVIFDGR....................................................................................................................... 433
63 -14.6003gg2_A mol:protein length:450 Sugar dehydrogenase, UDP-glucose/GDP-mannose dehydrogenase family  ali model follow..  12  1MSLDIAVVGIGYVGLVSATCFAELGANVRCIDTDRNKIEKMIARNVKAGRLRFGTEIEQAVPEADIIFIAVGTPADMSYVLDAARSIGRAMSRYILIVTKSTVPVGSYRLIRKAIQEELDKRIDFDIASNPEFLKEGNAIVVVGVDS--DRARELITSLYKPMLLNNFRVLFMDIASAEMTKYAANAMLATRISFMNDVANLCERVGADVSMVRLDVKALIRTAEDNGYRMEVLEAVERVNEKQKSILFDKFSTYYKGNVQGRCVAIWGLSFKPGTDDMREAPSLVLIEKLLEVGCRVRVYDPVAMKEAQKRLGDKEYTTDMYDAVRGAEALFHVTEWKEFR--------MPDWSALSQAMAASLVIDGR....................................................................................................................... 419
64 -14.6002raf_A mol:protein length:209 Putative Dinucleotide-Binding Oxidoreductase  ali model follow..  14  13.GMEITIFGKGNMGQAIGHNFEIAGHEVTYYGSKDQA-----------------------TTLGEIVIMAVPYPALAALAKQYATQL-----KGKIVVDITNADSSAAQELQQQLPDKAFNTTFAATSGQVNGKEPTTVLVAGNDDSAKQRFTRALADSPLEV------KDAGKLKRARELE................................................................................................................................................................................................................................................................................................................... 178
65 -14.3004a7p_A mol:protein length:446 UDP-GLUCOSE DEHYDROGENASE  ali model follow..  14  2.SVRIAMIGTGYVGLVSGACFSDFGHEVVCVDKDARKIDALVASNVKAGRLSFTTDLAEGVKDADAVFIAVGTPADLSYVFAAAREIAENLTKPSVIVTKSTVPVGTGDEVERIIAEVAPN-SGAKVVSNPEFLREGAAIVVVGDEFARQVMREIYRPLSLNQS---APVLFTGRRTSELIKYAANAFLAVKITFINEIADLCEQVGADVQEVSRDTLALMKTAADNETPLRIVEATVQVNDARKRAMGRKVIKAMGGDVRGKTVGILGLTFKPNTDDMRDAPSLSIIAALQDAGATVKAYDPEGVEQASKMLTDVEFVENPYAAADGADALVIVTEWDAFR--------ALDLTRIKNSLKSPVLVDLR....................................................................................................................... 416
66 -14.0002f1k_A mol:protein length:279 prephenate dehydrogenase  ali model follow..  12  1..MKIGVVGLGLIGASLAGDLRRRGHYLIGVSRQQSTCEKAVERQLVDEAGQDLSLLQTA---------IIFLCTPIQLILPTLEKLIPHLSPTAIVTDVASVK----TAIAEPASQLWSGFIGGPMAGTAAGIDGAEENLFVNDPEQLACLRSVLEPLGVK------IYLCTPADHDQAVAWISHMVSAALIQACAG................................................................................................................................................................................................................................................................................................... 194
67 -13.9004huj_A mol:protein length:220 Uncharacterized protein  ali model follow..  11  17.MTTYAIIGAGAIGSALAERFTAAQIPAIIANRGPASLSSVTDRFGA----SVKAVELKDALQADVVILAVPY-DSIADIVTQVSDW-----GGQIVVDASNAIDFPAFKPRDLGGRLSTEIVSELVPGADKGTGSRVLFLSGNHSDANRQVAELISSLGFAP------VDLGTLAASGPIQ................................................................................................................................................................................................................................................................................................................... 200
68 -13.8004r16_A mol:protein length:418 418aa long hypothetical UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase  ali model follow..  13  1..MRIAVLGLGYIGLPTAIMFASSGYDVVGYDIRSEVIKKINSKEVLSLGKLKVTDRVEDLKGSNVFIICVQTPPDLSYLERAIRTVAEVMDRGALVIIESTIPPGTTEKMARLLENLT---VDFYVAHAPERVMPGRIIIGGVSEKAANLAEKLYRSFVKGR------IFLTNATTAEMVKLMENTFRDVNIALANEFALLAHQYGVNVYEAIELAYLLLSNAKEDFGLIRIARRI---NERMPAFAAGLLFEALEKANIKPSEAIIAVLGLAYKGGTDDTRNSPALKFVEIIRNSVKEVRTYDPYVRGTHDSLEKVVEGADAIVIATDHPEFKS---------------VNWESIGKSMRHKIIIDGR....................................................................................................................... 398
69 -13.7004xr9_A mol:protein length:456 CalS8  ali model follow..  13  15.PLKVVIAGAGYVGTCLAVTLAGRGAEVVAVDSDPGTVADLRARDLAATGRLTASTSYDPVGAADVVIVTVGTPMVTDQLVAACEQIAPRLRAGQLVILKSTVSPGTTRTLVAPLLESG----DFGLAFCPERLAEGVAVVGGCGPRSAAAAERFWRSALGVD-----VRQVPSAESAEVVKLATNWWIDANVAIANELARYCAVLGVDVLDVIGAAWRDGRDRGVSLRTVETARAVNDDMPRHTAAVIADELVKLGRDRNDTTIAVLGAAFKNDTGDVRNTPVRGVVAALRDSGFRVRIFDPLADPAEIVARFGTAPAASLDEAVSGAGCLAFLAGHRQFH--------ELDFGALAERVDEPCLV.......................................................................................................................... 429
70 -13.0004wji_A mol:protein length:293 Putative cyclohexadienyl dehydrogenase and ADH prephenate dehydrogenase  ali model follow..  14  3QFQTIALIGIGLIGSSIARDIREKQLTIVVTTRSEATLKRAGELGLGDR---YTLSAAEAVEGAD----LVVVSVPVGASGAVAAEIAAHLKPGAIVTDVGSTKGSVIAQMAPHLPK-DVHFVPGPIAGTEHGPDAGFAGLFRGDEEAVARLRLFWETLGSM------VDEMDPKHHDKVLAIVSHL-----------AYNIVGTADDLETVTESEVIKYSASGFRDFTRLTMWRDVCLHNKDAILEMLARFSEDLAS....................................................................................................................................................................................................................................... 259
71 -12.9003vtf_A mol:protein length:444 UDP-glucose 6-dehydrogenase  ali model follow..  17  15.MASLSVLGLGYVGVVHAVGFALLGHRVVGYDVNPSIVEEALGRALSSGRLSFAESAEEAVAATDATFIAVGTPADLRYVEAAARAVGRGIRAKGLVVVKSTVPPGTTEGLVARAVAEEAGGVKFSVASNPEFLREGSALIVIGDERAASFLLDVYKAVDAP-------KLVMKPREAELVKYASNVFLALKISFANEVGLLAKRLGVDTYRVFEAV................................................................................................................................................................................................................................................................................ 257
72 -12.9003ojl_A mol:protein length:431 Cap5O  ali model follow..  14  5.GSKLTVVGLGYIGLPTSIMFAKHGVDVLGVDINQQTIDKLQNGQISIEEPGLQEVYEEVLSSSDVFIIAVPTPCDISLVMRALDSILPFLKKGNTIIVESTIAPKTMDDFVKPVIENL----DIYLVHCPERVLPGKIIIGGVTKACIEAGKRVYRTFVQGE------MIETDARTAEMSKLMENTYRDVNIALANELTKICNNLNINVLDVIEMA................................................................................................................................................................................................................................................................................ 244
73 -12.9004ol9_A mol:protein length:304 Putative 2-dehydropantoate 2-reductase  ali model follow..  12  4IATGIALVGPGAVGTTVAALLHKAGYSPLLCGHTPRAGIELRRDGADVVPGPVHTSPREVAGPVD----VLILAVKATQNDAARPWLTRLCDERTVVAVLQN---EQVEQVQPHCPSSAIVWCSAETQPQGWVRLRGEAALVVPTGPAAEQFAGLLRGAGATVDCDPDFT------TAAWRKLLVNALAGFMVRYVAECLAVARAEGARLDDEVVRLVRSAPQDMGTSMLADRAAHRPLEWDLRNGVIVRK.............................................................................................................................................................................................................................................. 272
74 -12.8003g79_A mol:protein length:478 NDP-N-acetyl-D-galactosaminuronic acid dehydrogenase  ali model follow..  10  18.IKKIGVLGMGYVGIPAAVLFADAPEKVLGFQRNSKSLEELIGKVVKAGKFECTPDFSRI-SELDAVTLAIQTPPDFSALIDGIRNVGKYLKPGMLVVLESTITPGTTEGMAKQILEEESGLEDFALAHAPERVMVGRLIVGGIDEASTKRAVELYSPVLTVG-----QVIPMSATAAEVTKTAENTFRDLQIAAINQLALYCEAMGINVYDVRTGVDSLKGEGITRAVLWSIYVLARKVNDFMPAHMYNLTVAALERLGKKMDGSKVAM--------LGWAFIKDSDDARNTPSEPYRDLCLKAGASVMVHDPYVVNYPGVEISDNLEEVVRNADAIVVLAGHSAYSSLKADWAKKVSAKANPVIIDGR....................................................................................................................... 450
75 -12.5003dzb_A mol:protein length:317 Prephenate dehydrogenase  ali model follow..  14  6..KTIYIAGLGLIGGSLALGIKRDHPEILGYNRSDYSRNIALERGIVDR---ATGDFKEFAPLADV---IILAVPIKQTMAYLKELADLDLKDNVIITDAGSTKREIVEAAERYLTGKNVQFVGSPMAGSHKGAIAADVTLFENKETTIPELKDILSGLKSR------YVEIDAAEHDRVTSQISH-FPHLLASGLMEQAADYAQAHEMTNHFAAGGFRDMTRIAESEPGM---ASILMTNGPAVLDRIEDFKKRLDH....................................................................................................................................................................................................................................... 261
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Robinson-Rechavi M, Godzik A. Structural Genomics of Thermotoga maritima Proteins Shows that Contact Order Is a Major Determinant of Protein Thermostability. Structure (Camb). 2005 Jun;13(6):857-60.