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Query: [P] KOG4505 Na+/H+ antiporter, from COG1018

Results of FFAS03 search in PDB1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MAWSQVEISKPHLAYAIIGGFTSLFMLCSLIIKEKLFLGEATMATATGLIFGPYVAKLFVPTSWGNTDYITEELARVLLVVEVFAAGAELPRAYMLRHWRSMFVMLLPVMIFGWLVSTGFMYALIPRLSFLESLAIAACITATDPVLASSIVGKGKFARRVPGHLRNMLLAESGCNDGMAIPFLYLAIYLIIEKPARHAGRDWVCIIILYECTFGCVLGAIIGVIARKMIKFSERRGLMDRESFLVFYFVLALFCGGIGTIIGVDDLLVSFCAGAAFSWDSWFSKKTEESHVSNVIDLLLNLSFFVYVGAIMPWPQFHMPHMDLSVWRLVVLAICILIARRIPAVLLFKSFVPDIINWREALFAGHFGPIGVGALYTCLVARAELEVHSTVPEPNDAIENPEIPNWYCIQVMWPVVCFLVLSSIIVHGSSIAFFMLGKRINTLALSFTRTRDSHFAFNLPRVRQGQSLPIKRVDALRSSANSIASSIRRRHPVNIQEDEDADISTVSLPEAAHLREERAESPRGGHYDAEEFPSEDYESRQPRRSNEEDREEEMNPGDETYLIGEDLVVEDSQGNIISHTSSRDANGPSIDEKLAQGDPKAKSFGRKFRSFLRRSYDTFQRNLHEPDDERQREPTLGHIESSIENHRPRYSRQNSESHLRENSVERRRREQVLTNIGDSESEDDNIPRPGIVPFYNENNESSSDTRNGLLSDNVSESRSRRPSRAPSAAVSSEGSPVEEDNEAQHRPNIRFLELTRAWELast
1 -56.7004czb_A mol:protein length:426 NA(+)/H(+) ANTIPORTER 1  ali model follow..  14  5.............MAIGYLGLALVLGSLVAKIAEKLKIPDIPLLLLLGLIIGPFLQIIPSDS----AMEIFEYAGPIGLIFILLGGAFTMRISLLKRVIKTVVRLDTITFLITLLISGFIFNMVL-PYTSPVGYLFGAITAATDPATLIPVFS----RVRTNPEVAITLEAESIFNDPLGIVSTSVILGLFGLFSSSN-----PLIDLITLAGGAIVVGLLLAKIYEKIIIHCDFHEYVLVLGGAMLLLYVGDDLLPSICGYGFSGYMAVAIMGLYLGDALDDIDYKYIVSFCDDLSLLARVFIFVFLGACIKLSMLEN----YFIPGLLVALGSIFLARPLGVFLGLI---GSKHSFKEKLYFALEGPRGVVPAALAVTVGIEILKNADKIPASITKYITPTDI---AGTIIIGTFMTILLSVILEASWAGMLALKLLGEYKPKYKEES..................................................................................................................................................................................................................................................................................................................... 424
2 -56.5004cz8_A mol:protein length:422 NA+/H+ ANTIPORTER, PUTATIVE  ali model follow..  20  3...........ELSLAEALFLILFTGVISMLISRRTGISYVPIFILTGLVIGPLLKLIPRDL----AHEIFDFVRVFGLVIILFTEGHNLSWRLLKKNMPTIVTLDTIGLILTALIAGFIFKVVF-NSSFLLGFLFGAIIGATDPATLIPLFR----QYRVKQDIETVIVTESIFNDPLGIVLTLIAISMLVPGYGGGIFST-GVIYFLYNVSVSISLGIFLGILGYKFIKRT---GIFDFPEIEAFSLSLAFLGFFIGERLDASGYLVATVTGIVLGNYKLLKPREKEVHFNDTLAALATIFIFVLLGAEMNLEVIWS----NLGKGLLVALGVMILARPLATLPLLKWW-----NFREYLFIALEGPRGVVPSALASLPLSLALKYKSP-----------LLTVHWGEIIMATVVITVLTSVIVETLWIPILKDKLDVG.............................................................................................................................................................................................................................................................................................................................. 422
3 -27.5005bz2_A mol:protein length:386 Na(+)/H(+) antiporter  ali model follow..  16  6..............HLLEIFYLLLAAQVMAFIFKRLNQPCVIGEVLAGVLVGPALLGLVH------EGEILEFLAELGAVFLLFMVGLETRLKDILAVGKEAFLVAVLGVALPFLGGYLYGLEI--GFETLPALFLGTALVATSVGCTARVLQELGV---LSRPYSRIILGAAVIDDVLGLIVLAVVNGVAETGQVE-------VGAITRLIVLSVVFVGLAVFLSTLIARLPLERL--PVGSPLGFALALGVGMAALAASIGLAPIVGAFLGGMLLSEV---REKYRLEEPIFAIESFLAPIFFAMVGVRLELSALAS--------PVVLVAGTVVTVIAILGKVLGGFLGALTQGVRSALTVG-MAPRGEVGLIVAALGLKA----------------------AVNEEEYAIVLFMVVFTTLF............................................................................................................................................................................................................................................................................................................................................. 366
4 -27.4004bwz_A mol:protein length:394 NA(+)/H(+) ANTIPORTER  ali model follow..  15  6..............HLLEIFYLLLAAQVCAFIFKRLNQPVVIGEVLAGVLVGPALLGLVH------EGEILEFLAELGAVFLLFMVGLETRLKDILAVGKEAFLVAVLGVALPFLGGYLYGLEI--GFETLPALFLGTALVATSVGITARVLQELGV---LSRPYSRIILGAAVIDDVLGLIVLACVNGVAETGQVE-------VGAITRLIVLSVVFVGLAVFLSTLIARLPLERL--PVGSPLGFALALGVGMAALAASIGLAPIVGAFLGGMLLSEV---REKYRLEEPIFAIESFLAPIFFAMVGVRLELSALAS--------PVVLVAGTVVTVIAILGKVLGGFLGALTQGVRSALTVG-MAPRGEVGLIVAALGLKA----------------------AVNEEEYAIVLFMVVFTTLFAPFALKPLIAWTERERAAKEGSENLYFQ................................................................................................................................................................................................................................................................................................................. 394
5 -19.7002mdf_A mol:protein length:57 Sodium/hydrogen exchanger 1  ali model follow..  20  1..............................................................................................................................GSKKKDNLLFGSIISAVDPVAVLAVFE----EIHINELLHILVFGESLLNDAVTVVLY............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 54
6 -14.6005mqf_S mol:protein length:2752 Serine/arginine repetitive matrix protein 2  ali model follow..  8  2.............................................................................................................................................................................................................................................................................................................................................................................YNGPRGSGTVQRNLSLVRGRRGERPDYKGEEELRRLEAALVKRPNP-----------DILDH--RVELRCLELEEMMEEQGYEEQQIQEKVATFRLMLLEKDVNPGGKEETPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPP 394
7 -14.4005mqf_T mol:protein length:908 Pre-mRNA-splicing factor CWC22 homolog  ali model follow..  6  171...NKVNISNISIIIQELLQENIVRGLLSRSVLQAQSASPIFTHVYAALVA----------------NSKFPQIGELILKRLIFRKGYRRNDKQLCLTASKFVAHLINQNVAHEVLCLEMLTLLLESVEVAIGFLCGLKLTQVSPRGINAILRNILHESEIDKRVQYMIE---------------VMFAVRKDGFKDHPIILEGLDLVEED-------------------DQFTHMLPLEDDYNPEDVLNVFKMDPNFMENEEKYKAIKKEILDEGDTDSNTDQDAGSSEE-TEINLVSFRRTIYLAIQSSLDFEECAHKLLKMEFPESQTKELCNMILD------------------QQRTYEKFFGLLA--MESFEGIFKEQYDTIHRLETNKLRNVAKMFAHLLYTDSLLECIKLSEETTTSSSRIFVKIFFQELCEYMGLPKLNARLKDETLQPFFEGLLPRDNPRNTRFAINFFTSIGLGGLTDELREHLKNTPKVIVAQKPDVEQNKSSPSSSSSASSSSESDSSDSDSDSSDSSSESSSEESDSSSISSHSSASANDVRKKGHGKTRSKEVDKLIRNQQTNDRKQKERRQEHGHQETRTERERRSEKHRDQNSSGSNWRDPITKYTSDKDVPSERNNYSRVANDRDQEMHIDLENKHGDPKKKRGERRNSFSENEKHTHRIKDSENFRRKDRSKSKEMNRKHSGSRSDEDRYQNGAERRWEKSSRYSEQSRESKKNQDRRREKSPAKQK... 908
8 -13.8002m7x_A mol:protein length:38 Na(+)/H(+) antiporter  ali model follow..  55  2.......................................................................................................................SKKKLFPQINFLGSLLIAGCITSTDPVLSALIVGKK............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 37
9 -13.4005z10_A mol:protein length:2547 Piezo-type mechanosensitive ion channel component 1  ali model follow..  8  800FVRRLLELHVFKLVALYTVWVLVVLWAFALPYPRFRPMASCLSTVWTCIII----------------------VCKMLYQLKIVTNLQPLEINQSLLYRGPVDPANWFGVRKGYPNLGYIQNHLQ----ILLLLVFEAVVAPLPAQAVCADGTRQRLDQDLLSCLKYFIN-KFGLENFMVILHGCWLVAILTRRRREAIARLWPNYCLFLTLFLLYQYLLCLGMMNSALIKWLYLPDFFRAPNSTNLISDFLLLLCASQQRMAGINLVVVFVAGA-----------TRISIFG--LGYLLACFYLLLFGTTL----QKDTRAQLVLWDCLILYNVTVIISKNMLSLLSCVFV-EQMQSNFCWVIQLFSLVCTVKGYYDPKEMMTRDRDCLLPVEEAGIFLLLQRRIFLSHYFLHVSADLKATALQASRGFALYNAANLKSINFHRQIEEKSLAQLKRQMKRIRAKQEKYRQSQASRGQLQSKDPQDPSQEPGPDSPGGSSPPRRQWWRPWLDHATVIHSGDYFLFESDSEEEEEALPEDPRPAAQSAFQMAYQAWVTNAQTVLRQRRERARQERAEQLASGGDLNPDVEPVDVPEDEMAGRSHMMQRVLSTMQFLWVLGQATVDGLTRWLRAFTKHHRTMSDVLCAERYLLTQELLRVGEVRRGVLDQLYVGEDEATLSGPVETRDGPSTASSGLGAEEPLSSMTDDTSSPLSTGYNTRSGSEEIVTDAGDLQAGTSLHGSQELLANARTRMRTASE.. 1647
10 -13.0004n7x_A mol:protein length:312 Transporter, sodium/bile acid symporter family  ali model follow..  13  6...........................MLVKITRLFPV--ALLLSVAAYFRPTTFTGI-------------GPYVGPLLMLIMFAMGVTLRLDDFKRVLSRPAPVA-AATFLHYLIMPLTAWILAMLFRMPPDLSAGMVLVGSVASGTASNVMIYLAKGDVA--LSVTISAVSTLVGVFATPLLTRLYV----DATISVDVVGMLKSILQIVVIPITAGLVIHHTFTKTVKRIEPYLPAMSMVCILAIISAVVAVIIAVILHNGIGLLSGYWGGKLFGFDESTCRTLAIA--------MQNSGLAATLGKIYFSPLAALPGALFSVWHNLSGSLLAGYWSG.................................................................................................................................................................................................................................................................................................................................................................................................................................. 304
11 -12.9003zux_A mol:protein length:332 TRANSPORTER  ali model follow..  12  1................MVAASMNILSKISSFIGKTFSL--AALFAAAAFFAPDTFKWA-------------GPYIPWLLGIIMFGMGLTLKPSDFDILFKHPKVVI-IGVIAQFAIMPATAWCLSKLLNLPAEIAVGVILVGCCPGGTASNVMTYLARGNVA--LSVAVTSVSTLTSPLLTPAIFLMLA----GEMLEIQAAGMLMSIVKMVLLPIVLGLIVHKVLGSKTEKLTDALPLVSVAAIVLIIGAVVGIFAVVVLHNGIGYLLGFFAAKWTGLPYDAQKALTIEVGMQNSG----------LAAALAAAHFAAAPVVAVPGALFSVWHNIS...................................................................................................................................................................................................................................................................................................................................................................................................................................... 302
12 -12.3005xjc_x mol:protein length:703 Protein CASC3  ali model follow..  7  4........................................................................................................................................................................................................................................................................................................................................................................................................................................................................RRRQRASQDTEDEESGASGSDSGGSPLRGGGSCSGSAGGGGSGSLPSQRGGRTGALHLRRVESGGAKSAEESECESEDGIEGDAVLSDYESAEDSEGEEGEYSEEENSKVELKSEANDAVNSSTKEEKGEEKPDTKSTVTGERQSGDGQESTEPVENKVGKKGPKHLDDDEDRKNPAYIPRKGLFFEHDLRGQTQEEEVRPKGRQRKLWKDEGRWEHDKFREDEQSRQELIALYGYDIRSAHNPDDIKPRRIRKPRYGSPPQRDPNWNGERLNKSHRHQGLGGTLPPRTFINRNAAGTGRMSA 309
13 -12.0006ff4_Y mol:protein length:904 Serine/arginine repetitive matrix protein 1  ali model follow..  11  3............................................................................................................................................................................................................................................................................AGFFRGT---------SAEQDNRFSNKQKKLLKQLKF------------ECLEKKVDMSKVNLEVIKPWITKRVTEIL------------------------GFEDDVVIEFIFNQLEVKNPDSKM-----------------------MQINLTGFLNGKNAREFMGELWPLLLSAQENIAGIPSAFLELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKS 426
14 -11.9005fl8_r mol:protein length:767 Protein SDA1  ali model follow..  8  112..............................................................................LKQLLLEHHKSLPFELKEKILSCLTMLRNKDVITAEELIQSLFPLLVAYSSHGNSLGVNSHAKELRKIIYTNLISLNGKNQKLNKSTQAVCFNLLDQPDSQGIWATKLTRELWRRGIWDDSRTVEIMTQAALHQDVKIVMSGVMFFLDAD--REREENFEENSEDEDGFDLDALRHKMQVNKKTGRRGKKLENAIKTVKKKKKNGPGAPQGYLNFSAIHLLRDPQGFALFKEHLSGKTKNKFDMEQ-------ISLMQLLSRLI-------------------------GTHKLIVLGIYTFFLKYLTPKQRDVTRIMSACAQACHDLVPPEVINVMVR-KIADEFVSDGVANEVAAAGINTIREICSRAPLAIDEILLQDLVEYKGSKAKGVNMAAKSLIALYRDVAPEMLKKKDRGKNAAMEVQEAKKGGKDSKRPQFGADNSVQGIAGIELLAKWKKEHGEESENEDADANWEVDVDSEEDDVDGEWVTMDSDKEYDVDMEDSDDEKDNAKGKESDSDLELSDDDDEKEVKDEQEDADIDPEAAFREIASTRILTPADFAKLQELRNEESVAKIMGIHKQDKREELVDASTLTGPIKYKQSREERLQKVLEGREGRDKFGSRRGKRDNMRSTTNREKERRKNFVMSIHKRSVRGKQKMSLRDKQKVLRAHITKQKKKG 766
15 -11.6005nnv_A mol:protein length:282 Chromosome partition protein Smc,Chromosome partition protein Smc  ali model follow..  8  2...............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................SGMEKVQMAKEEELAESSAISAKEAKIEDTRDKIQALDESVDELQQVLLVTSEELEKLEGRKEVLKERKKNAVQNQEQLEEAIVQFQQKETVLKEELSKQEAVFETLQAEVKQLRAQVKEKQQALSLHNENVEEKIESGGSGGSRLTKQKQTQSSTKESLSNELTELKIAAAKKEQACKGEEDNLARLKKELTETELALKEAKEDLSFLTSEMSSSTSGEEKLEEAAKHKLNDKTKTIELIALRRDQRIKLQHGLDTYERELKEMKRLYKQKTTLLKDEE 281
16 -11.4004atv_A mol:protein length:401 NA(+)/H(+) ANTIPORTER NHAA  ali model follow..  12  14..................GGIILIIAAILAMIMANSGATSGWYHDFLETPVQ------LRVGSLEINKNMLLWINDALMAVFFLLVGLEVKRELMQGSLASLRQAAFPVIAAIGGMIVPTLLYLAFNYADPITREGWAIPAATDIAFALGVLA---LGSRVPLALKIFLMALAIIDDLGAIIIIALF--------------------YTNDLSMASLGVAAVAIAVLAVLNLCGARRT-------GVYILVGVVLWTAVLKSGVHATLAGVIVGFFIPLKEK-HGRSPAKRLEHVLHPWVAYLILPLFAFANAGVSLGGVTLDGLTSILPLIIAGMLIGKPLGISLFCLAHLPEGTTYQQIMVVGILCGIGTMSIFIASLAFGSVD-----------------------PELINWAKLGILVGSISSAVIGYSWLRVRLRPSVEFRVPGSENLY................................................................................................................................................................................................................................................................................................................. 399
17 -11.3006fhs_H mol:protein length:491 les2  ali model follow..  7  12.........................................................................................................................................................................................................................................................................................................................................................................................................................................................RASQAITDLADRDRESDHSHGPISSRMSSFNSSSRSRLPGKGIASVSRSEAGGASDPEHIHLTVKLPSSKLRQATSSSGIKKAGSVGSSSSSSGGGKAAVKRARGGKRSRVLESSEEEEEENEVEVLGDEDEEEEEEEDEIEVREGEGYDEDEEDVEDEDEEMQDLGEEDADGEDDEMDVDAEGEEDADGDVNMDAGVVGARATTVRAVPPAIKVTKPPKESPSNGKAATASKANDNAVPVKRPAPDSDDESLSSLESEPEEEVNVAGGEDAEGEDDDAEGEVDAEGEEEEEEEEIEVADEDAEGEDVEQDEDEDEEE 329
18 -10.8006ehl_A mol:protein length:739 Nucleoprotein  ali model follow..  8  17.............................................................................................................................SDMDYHKILTAG--LSVQQGIVRQRVIPQVNNLEEICQLIIQAFEAGVDFQESADSFLLMLCLHHAYQGDYKLFLESGAVKYL------GFRFEVKKRDGVKRLEELLPAVSSGKNIKRTLAAMPEEETTEANAGQF---SFASLFLPKLVVGEKACLEKVQRQIQVHAEQGLIQYPTAWQSVGHMMVIFR---------------LMRTNFLIKFLLIHQGMHMVAGHDANDAV--SVAQARFSGLLIVKTVLDHILQKTERGVRLHPLARTAKVKNEVNSFKAALSSLAPFARLLNLLEHGLFPQLSAIALGVATAHGSTEQYQQLREAATEAEKQLQQYAESRELDHLGLDDQEKKILMNFHQKKNEISFQQTNAMVTLRKERLAKLTEAITAASLPKTSGHYDDDDDIPFPGPINDDDNPGHQDDDPTDSQDTTIPDVVVDPDDGSYGEYQSYSENGMNAPDDLVLFDLDEDDEDTKPVPNRSTKGGQQKNSQKGQHIEGRQTQSRPIQNVPGPHRTIHHASAPLTDNDRRNEPSGSTSPRMLTPINEEADPLDDADDETSSLPPLESDDEEQDRDGTSNRTPTVAPPAPVYRDHSEKKELPQDEQQDQDHTQEARNQDSDNTQSEHSFE 649
19 -10.8005z3g_b mol:protein length:427 rRNA-processing protein EBP2  ali model follow..  9  65...........................................................................................................................................................................................................................................................................................................................................................................................................................................................AADTEEYQSQALSKKEKRKLKKELKKMQEQDATEAQKHMSGDEDESGDDREEEEEEEEEEEGRLDLEKLAKSDSESEDDSESENDSEEDEDVVAKEESEEKEEQEEEQDVPLSDVEFDSDADVVPHHKLTVNNTKAMKHALERVQLPWKKHSFQEHQSVTSETNTDEHIKDIYDDTERELAFYKQSLDAVLVARDELKRLKVPFKRPLDYFAEMVKSDEHMDKIKGKLIEEASDKKAREEARRQRQLKKFGKQVQNATLQKRQLEKRETLEKIKSLKNKRKHNEIDHSEFNVGVEEEVEGKRFDRGRPNGKRAAKN 380
20 -10.3006e11_d mol:protein length:993 Translocon component PTEX150  ali model follow..  6  1............................................................................................................................................................................................................................................................................................................................................................................................................................MRIIILALLIVCTIINYYCAVQNNGNKSLNVMPTCSMPGNDSDSNDNETGDVDNDKNNELGNANDNNEMNNENAESKNMQGENSNNQEQLNENVHANDDAMYEGTPSSDNPPQENVDANNNEQEYGPPQEEPVSENNVENVEVATDDSGNDNINNNDNFNNNDNYNDNDNFNEEPPSDDGNKNEDELTEGNQSDDKPMNEEEATINEMGKITNPFEDMLKGKVDDMDIGKMMNKDNLQSFLSSLTGNKDGSGKNPLSDMMNIFGVPQTGKEGAEGGVNKENQMKQINELKDKLETMLKGAGVNVDKIKDSIKNNDLLKNKQLLKEAISKLTLDPSMMNMLNNKDGAN 347
21 -10.3003pgw_S mol:protein length:437 U1-70K  ali model follow..  8  104......................................................................................................................................................................................................................................................................................................................................................................................................................................TLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHERDMHSAYKHADGKKIDGRRVLVDVERGRTVKGWRPRRLGGGLGGTRRGGADVNIRHSGRDDTSRYDERPGPSPLPHRDRDRDRERERRERSRE---RDKERERRRSRSRDRRRRSRSRDKEERRRSRERSKDKDRDRKRRSSRSRERARRERERKEELRGGGGDMAEPSEAGDAPPDDGPPGELGPDGPDGPEEKGRDRDRERRRSHRSERERRRDRDRDRDRDREHKRGERGSERGRDEARGGGGGQDNGLEGLGNDSRDMYMESEGGDGYLAPENGYLMEAAPE 437
22 -10.1005cwd_A mol:protein length:179 Designed helical repeat protein  ali model follow..  5  2...........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................STKEDARSTCEKAARKAAESNDEEVAKQAAKDCLEVAKQAGMPTKEAARSFCEAAARAAAESNDEEVAKIAAKACLEVAKQAGMPTKEAARSFCEAAARAAAESNDEEVAKIAAKACLEVAKQAGMPTKEAARSFCEAAKRAAKESNDEEVEKIAKKACKEVAKQAGMPWLE 173
23 -10.1005lzs_b mol:protein length:245 Uncharacterized protein,eL29  ali model follow..  4  2...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................AKSKNHTTHNQSRKWHRNGIKKPRSQRYESLKGVDPKFLRNMRFAKKHNKKGLKKMQANNAKAMAARAEAIKALVKPKEVKPTIPKGVSRKLHRLAYIAHPKLGRRARARIARGLRLSRPQTKAKAKTEPQIKGKVKAQIKAQAQAQIKSKGKGKAQAETKPKAQAETKPKAQAQAKPKAQAQGKPKAQAQGKPKAQAQAKPKAQAQAKPKAQAQTKPKAQATPAAPVPAQAPPKGAQPPAKAP 245
24 -10.1005iy6_S mol:protein length:517 General transcription factor IIF subunit 1  ali model follow..  5  159.............................................................................................................................................................................................................................................................................................................................................................................................................................................................EAEEEWERRNKVLNHFSIMQQRRLKDQDQDEDEEEKEKRGRRKASELRIHDLEDDLEMSSDASDASGEEGGRVPKAKKKAPLAKGGRKKKKKKGSDDEAFEDSDDGDFEGQEVDYMSDGSSSSQEEPESKAKAPQQEEGPKGVDEQSDSSEESEEEKPPEEDKEEEEEKKAPTPQEKKRRKDSSEESDSSEESDIDSEASSALFMAKKKTPPKRERKPSGGSSRGNSRPGTPSAEGGSTSSTLRAAASKLEQGKRVSEMPAAKRLRLDTGPQSLSGKSTPQPPSGKTTPNSGDVQVTEDAVRRYLTRKPMTTKD 472
25 -9.9606d4h_A mol:protein length:1455 Protein patched homolog 1  ali model follow..  8  969...........................................................................................................................................IEYAQFPFYLNGLRDTSDFVEAIEKVRTICS-NYTSLGLSSYPNGYPFLFWEQ------------YIGLRHWLLLFISVVLACTFLVCAVF-------LLNPWTAGIIVMVLALMTVELF------GMMGLI--GI-------------------KLSAVPVVILIASVGIGVEFTV---------------------------VALAFLTAIGDKNR-RAVLALEHMFLDGAVSTLLGVLMLAGSEFD-----FIVRYFFAVLAILTILGVLNGLVLLPVLLSFF----------------------------------------------------GPYPEVSPANGLNRLPTPSPEPPPSVVRFAMPPGHTHSGSDSSDSEYSSQTTVSGLSEELRHYEAQQGAGGPAHQVIVEATENPVFAHSTVVHPESRHHPPSNPRQQPHLDSGSLPPGRQGQQPRRDPPREGLWPPPYRPRRDAFEISTEGHSGPSNRARWGPRGARSHNPRNPASTAMGSSVPGYCQPITTVTASASVTVAVHPPPVPGPGRNPRGGLCPGYPETDHGLFEDPHVPFHVRCERRDSKVEVIELQDVECEERPRGSSSNDYKDDDDK..... 1455
26 -9.8205o9z_K mol:protein length:439 Microfibrillar-associated protein 1  ali model follow..  6  48........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................APMESSDEEDEEFQFIKKAKEQEAEPEEQEEDSSSDPRLRRLQNRISEDVEERLARHRKIVEPEVVGESDSEVEGDAWRMEREDSSEEEEEEIDDEEIERRRGMMRQRAQERKNEEMEVMEVEDEGRSGEESESESEYEEYTDSEDEMEPRLKPVFIRKKDRVTVQEREAEALKQKELEQEAKRMAEERRKYTLKIVEEETKKELEENKRSLAALDALNTDDENDEEEYEAWKVRELKRIKRDREDREALEKEKAEIERMRNLTEEERRAELRANGKVITNKAVKGK 334
27 -9.6305gjv_A mol:protein length:1873 Voltage-dependent L-type calcium channel subunit alpha-1S  ali model follow..  9 1044..........FFIIYIILIAFFMMNIFVGFVIVTQYQVWYVVYLMFALIMLNTICLGMQHYHQSEEMNHISDILNVAFTIIFTLEMILKLLAFKARGYFGDPWNVFDFLIVIGSIIDVILSEIDTFLASSGGLYCLGGGCGNVDPDESARISSAFFRLFRVMRLIKLLSRAE-----GVRTLLWTFIKSF-------QALPYVALLIVMLFFIYAVIGMQMFGKIALVDGTQINRNNNFQTFPQAVLLLNFAYYYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGKHLDVVTLLRRIQPPLGFGKFCPHRVACKRLVGMNM-TVTFNATLFALVRTALKIKTEGNFEQANEELRAIIKKIW--PIGVGKFYATFLIQEHFRKFMKRQEEYYGYRPKKDTVQIQAG-------LRTIEEEAAPEIRRTISGDLTAEEELERAMVEAAMEERIFRRTGGLFGQVDTFLERTNSLPPVMANQRPLQFAEIEMEELESPVFLEDFPQDARTNPLARANTNNANANVAYGNSNHSNNQMFSSVHCEREFPGEAETPAAGRGALSHSHRALGPHSKPCAGKLNGQLVQPGMPINQAPPAPCQQPSTDPPERGQRRTSLTGSLQDEAPQRRSSEGSTPRRPAPATALLIQEALVRGGLDTLAADAGFVTATSQALADACQMEPEEVEVAATELLKARESVQGMASVPGSLSRRSSLGSLDQVQGSQETLIPPR............................ 1872
28 -9.6005oqm_Q mol:protein length:747 Transcription initiation factor IIF subunit alpha  ali model follow..  6  407.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................XXXXXXXXXLTIDEAEKRMDKKSGEVPRWLMKHLDNIGTTTTRYDRTRRKLKAVADQQAMDEDDRDDNSEVELDYDEEFADDEEAPIIDGNEQENKESEQRIKKEMLQANAMGLRDEEAPSENEEDELFGEKKIDEDGERIKKALQKTELAALYSSDENEINPYLSESDIENKENESPVKKEEDSDTLSKSKRSSPKKQQKKATNAHVHKEPTLRVKSIKNCVIILKGDKKILKSFPEGEWNPQTTKAVDSSNNASNTVPSPIKQEEGLNSTVAEREETPAPTITEKD 694
29 -9.4805mke_A mol:protein length:968 Polycystin-2  ali model follow..  8  223...........ELVTYLLFLIVLCILTYGMMSSNVYYYTRMMSQLFLNLLLGVPRIRQLRVRN--GSCSIPQDLRDEIKECYDVYSVSSEDRAPFGPRNGTAWIYTSEKDLNGSSHWGIIATY-------------AGYYLSRTREETAAQVASLKKNVWLDRGTRATFIDFSVYNANINL-FCVVRLLVEFPATGGVIPSWQFQPLKLIRYVTTIFCFFIFYYVVEEILEIRIHKNCLD----VIVVLSVVAIGINIYRTSNVEVLLQ------FLEDQNTFPNFEHLAYWQIQFNNIAAVTVFFVWIKLFKFINFNRTMSQLSLFGFAIMFFIIFLAYAQLAYLVFGTQVDDFSTFQECIFTQFRIILGLGPIYFTTFV-----------------------------FFMFFILLNMFLAIINDTYS----------EVKSDLAQQKAEMELSDLIRKGYHKALVKLKLKKNTVDDISESLRQGGGKLNFDELRQDLKGKGHTDAEIEAIFTKYDQDGDQELTEHEHQQMRDDLEKEREDLDLDHSSLPRPMSSRSFPRSLDDSEEDDDEDSGHSSRRRGSISSGVSYEEFQVLVRRVDRMEHSIGSIVSKIDAVIVKLEIMERAKLKRREVLGRLLDGVAEDERLGRDSEIHREQMERLVREELERWESDDAASQISHGLGTPVGLNGQPRPRSSRPSSSQSTEGMEGAGGNGSSN....................................... 965
30 -9.4105a1s_A mol:protein length:448 CITRATE-SODIUM SYMPORTER  ali model follow..  12  20....RFKIFGMPLPLYAFALITLLLSHFYNAIPTDL-VGGFALMFVMGAIFGEIGKRLPIFNKYIGGAPVMIFLVNLFIAVLITGAILSVNRKLLLKSLLGYIPTILAGIVGASLFGIVIG--LCFGIPVDRIMMLYVL-----PIMG------------------------GGNGAG-AVPLSEIYHSVTGRSREE----------YYSTAIAILTIANIFAIIFAALLDMVDEKAGQITHRETAVGMVLSTTCFLLAYVIHYFAWMVLIVAALNASGLCSPEIKAGAKRLSDFFSKQLLWVLMVGVGVCYT--DLQEIIDALTFANVVIAAIIVVGAVVGAAIGGLIGFYPIESSITAGLCMANRGGSGDLEVLSACNRMNLISYAQISSRLGGGIVLVIASIV................................................................................................................................................................................................................................................................................................................................................................. 441
31 -9.3703rlb_A mol:protein length:192 ThiT  ali model follow..  10  2............................................................................................................................................................AMSNSKFNVRLLTEI------AFMAALAFIISLIPNTVYGWIIVEIACIPILLLSLRRGLTAGLVGGLIWG-ILSMITGHAYILSLSQAFLEYLVAPVSLGIAGLFRQK--LAPVLLGTFVA--------VLLKYFFHFIAGIIFWSQYAWKGWGAVAYSLAVNGISGILTAIAAFVILIIFVKKFPKLF............................................................................................................................................................................................................................................................................................................................................................................................................................. 179
32 -9.3605z56_Z mol:protein length:619 BUD13 homolog  ali model follow..  7  175.........................................................................................................................................................................................................................................................................................................................................................................................................................................................SPPRRIRHDSSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHGSSDISSPRRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERASSKTSPHWKESGASHLSFPKNSKYEYDPDISPPRKKQAKSHFGDKKQLDSKGDCQKATDSDLSSPRHKQSPGHQDSDSDLSPPRNRPRHRSSDSDLSPPRRRQRTKSSDSDLSPPRRSQPPGKKAAHMYSGAKTGLVLTDIQREQQELKEQDQETMAFEAEFQYAETVFRDKSGRKRNLKLERLEQRRKAEKDSERDE 492
33 -9.3605fyw_Q mol:protein length:735 TRANSCRIPTION INITIATION FACTOR IIF SUBUNIT ALPHA  ali model follow..  6  407...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................DEAEKRMDKKSGEVPRWLMKHLDNIGTTTTRYDRTRRKLKAVADQQAMDEDDRDDNSEVELDYDEEFADDEEAPIIDGNEQENKESEQRIKKEMLQANAMGLRDEEAPSENEEDELFGEKKIDEDGERIKKALQKTELAALYSSDENEINPYLSESDIENKENESPVKKEEDSDTLSKSKRSSPKKQQKKATNAHVHKEPTLRVKSIKNCVIILKGDKKILKSFPEGEWNPQTTKAVDSSNNASNTVPSPIKQEEGLNSTVAEREETPAPTITEKD 682
34 -9.2406bw5_A mol:protein length:417 UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase  ali model follow..  8  3.AFSELPMPLLINLIVSLLGFVATVTLIPAFRGSRQQIPES-VISGAVFLIILFCFIPFPFLNCFPHHEFVALIGALLAICCMIFLGFADDVLNLRWRHKLLLPTAASLPLLMVYFTNFGNTTIVVPKPLYYVYMGLLAVFCTNAI--------------------NILAGINGLEAGQSLVISASIIVFNLVELEGDCRDDHVFSLYFMIPFFFTTLGLLVGDTFCYFAGMTFA-GILGHFSKTMLLFFMPQVFNFLYSLPQLLHIIPCPRHRIPRLNIKTGKLEMSYSKFSLSFLGTFILKVAESLQLVTVHQSETEDGEFTECNNMTLINLLLKVLRNLTLLLLLLQILGSAITFSIRYQLVFYDVTNSLEVLF.............................................................................................................................................................................................................................................................................................................................................................................................. 416
35 -9.2206ftg_5 mol:protein length:705 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A  ali model follow..  9  16...........TLLKLLILSMAAVLSFSTRLFA--FNYRTTRFLAEEGFYKFHNWFDDRAWYPLGRIIGGTLYPGLMITSAAIYHVLHFFHITI------DIRNVCVFLAPLFSSFTTIVTYHLTKELKDAGAGLLAAAMIAVVPGYISRSVAG---------------------NEGIAIFCMLLTYYMWIKAVKTGSIYWAAKCALAYFYMVSSWGGIPLHVLVLMLTGRFSHRIYVAYCTVYCLGTILSMQIVLSSEHMAAFGVFGLCQIHAFVDYLRSKLNPQQFEVLFRSVISLVGFVLLTVGALLMLTGKISP---------WTGRFYSLLDPSYAKNNIPIIASVSEHQPTTWSSYYFDLQLL-VFMFPVGLYYCFSNLSDARIFIIMYGVTSMYFSAVMVRLMLVLAPVMCILSGIGVSQVLSTYMKNLDISRPDKKSKKQQDSTYPIKN............................................................................................................................................................................................................................................................................................................. 454
36 -9.2106d0j_A mol:protein length:421 CLC-type fluoride/proton antiporter  ali model follow..  10  21........................................GLLSLVIGVLAGAVDTFFGKILLFLSA--LFLPIIGICFTYLFQPQGMNLVFLVGQEEEKDIPLRLIPFVMVGTWLT----------------HLFGGSAGREGVAVQLGATIANRLGNWVRLEKYASTLIMIGMAAGFAGLFTFFALEVLVIGK------------FSHHALLPALLAAFTASTTSQWLGLEKFSLMLPQSVDLTIPVFLKLLVIGLI------GMVGGSFAGCLETMKRIMKRRFPNPLWRIGIGALALVLLFVLLGTNLISASFTNQPIYSYDWLLKLVLTVLTISSEVTPLFAIGSSLGVVLAPLFGLPIELVAALGYASVFGSAT-------------STLFAPIFIGGEVFGFQNLPFFVIVCSVAYFISKPYSI........................................................................................................................................................................................................................................................................................................................................ 398
37 -9.2006fec_u mol:protein length:636 Eukaryotic translation initiation factor 4B  ali model follow..  7  318...............................................................................................................................................................................................................................................................................................................................................................................................................................................................EDRYDRRDDRSWSSRDDYSRDDYRRDDRGPPQRPKLNLKPRSTPKEDDSSASTSQSTRAASIFGGAKPVDTAAREREVEERLQKEQEKLQRQLDEPKLERRPRERHPSWRSEETQERERSRTGSESSQTGTSTTSSRNARRRESEKSLENETLNKEEDCHSPTSKPPKPDQPLKVMPAPPPKENAWVKRSSNPPARSQSSDTEQQSPTSGGGKVAPAQPSEEGPGRKDENKVDGMNAPKGQTGNSSRGPGDGGNRDHWKESDRKDGKKDQDSRSAPEPKKPEENPASKFSSASKYAALSVDGEDENEGEDYA 629
38 -9.1805oge_A mol:protein length:337 GDP-mannose transporter 1  ali model follow..  7  23............ISILSYCGSSILMTVTNKFVVNLKDFNMNFVMLFVQSLVCTITLIILRILGYAKFRSLNKTDAKNWFPISFLLVLLAVPIYTIFKNLTIILIAYGELSSFLLMVLSSVV-ATWGDQQAVAAKAASLAEGAAGAVMFTNCITSALFVLIMRKRIKLT-DFDTMFYNNVLALPILLLFSFCVEDWSSVNLTNNFSNDSLTAMIISGVASVGISYCSGWCVRVTSSTTYMVGALNKLPIALSGLIFFD-RNFLSILSIFIGFLSGIIYAVAKQKKQQAQPLR.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 336
39 -9.1805x9r_A mol:protein length:438 Citrate-sodium symporter  ali model follow..  12  10....GFKIFGMPLPLYAFALITLLLSHFYNALPTDI-VGGFAIMFIIGAIFGEIGKRLPIFNKYIGGAPVMIFLVAAYFVYAIFTQKEIDAISNVMDKSN--FLNLFIAVLITGAILSVNRRLLLKSLLGYIPTILMGIVGASIFGIAIGLVFGIPVDRIMMLYVLPIMG--GGNGAG-AVPLSEIYHSVTGRSREE----------YYSTAIAILTIANIFAIVFAAVLDIIDEKTGQITHRETAVGLVLSTTCFLLAYVIHYFAWMVLIVAALNASGLCSPEIKAGAKRLSDFFSKQLLWVLMVGVGVCYT--DLQEIINAITFANVVIAAIIVIGAVLGAAIGGLMGFFPIESAITAGLCMANRGGSGDLEVLSACNRMNLISYAQISSRLGGGIVLVIASIV................................................................................................................................................................................................................................................................................................................................................................. 431
40 -9.1506gct_A mol:protein length:541 Neutral amino acid transporter B(0)  ali model follow..  13  45...........................VRRCLRANLLVLLTVVAVVAGVALGLGVSGAGGALALGPGELLLRLLRMIILPLVLIGGAASLDPGALGRLGAWALLFFLVTTLLASALGVGLALALQPGLDLARNIFPSNLVSAAFRSYSTTYEERNITGTRVKVPVGQEVEG----MNILGLVVFAIVFGVALRKLGPEGELLIRFFNSFNEATMVLVVG-IMFLVAGKIVEMEDVGLLFARLGKYILCCLLGHAIHGLLVLKNPYRFLWGIVTPLATAFGTSSSSATMMKCVEENNGVAKHISRFILIGATV----------NMDGAALFQCVAAVFIAQLSQQSLDFVKIITILVT----ATASSVGAAGIGGVLTLAIILEAVN-----PVDHISLILAVDWLVDRSCTVLNVEGDALGAGLLQN............................................................................................................................................................................................................................................................................................................................................ 484
41 -9.0904v1n_Q mol:protein length:734 TRANSCRIPTION INITIATION FACTOR IIF SUBUNIT ALPHA  ali model follow..  7  402...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................DEAEKRMDKKSGEVPRWLMKHLDNIGTTTTRYDRTRRKLKAVADQQAMDEDDRDDNSEVELDYDEEFADDEEAPIIDGNEQENKESEQRIKKEMLQANAMGLRDEEAPSGNEEDELFGEKKIDEDGEKIKKALQKTELAALYSSDEDEINPYLSESDIENKENEPSVKKEEDIDSLSKSKKSSPKKQQKKTANAHVHKEPNLRVKSIKDCVIILKGDKKVLKSFPEGEWNPHAAKIKDISGNESNAVSAPIKKEKPLESIVVQEKETPAPLITEQD 677
42 -9.0206ez8_A mol:protein length:3138 Huntingtin  ali model follow..  7  96.......................................................................................................................................VNHCLTICENIVAQSVRNSPEFQKLLGIAMELFLLC---SDDA--------------------------VRMVADECLNKVIKALMDSNLPRLQLELY--KEIKKNGAPRSLRAALWRFA-ELAHLVRPQ--CRPYLVNLLLTRTSKRPEESVQETLAAAVPKIMASFIKVLLKAFIANLKSSSPTIRRTAAGSAVSICQHSRRTQYFYSWLLNVLLGLLVPVEDE-------ILGVLLTLRYLVPLLQQQVKDTSLKGSFGVTRKEMEVSPSAEQLVQVYELTLHTQHQDHNVVTGALELLQQLFRTPPPELLQTLTAVGGIGQLTAAKEESGGRSRSGSIVELIAGGGSSCSPVLSRKQKGKVLLGEEEALEDDSESRSDVSSSALTASVKDEISGELAASSGVSTPGSAGHDIITEQPRSQHTLQADSVDLASCDLTSSATDGDEEDILSHSSSQVSAVPSDPAMDLNDGTQASSPISDSSQTTTEGPDSAVTPSDSSEIVLDGTDNQYLGLQIGQPQDEDEEATGILPDEASEAFRNSSMALQQAHLLKNMSHCRQPSDSSVDKFVLRDEATEPGDQENKPCRIKGDIGQSTDDDSAP...................... 676
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Godzik A. Discovering new genes with advanced homology detection. Trends Biotechnol. 2002 Aug;20(8):315-6.