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Query: [H] COG0001 Glutamate-1-semialdehyde aminotransferase, from COG1018

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MPGGVSSPVRAFKSVGGQPIVFDHVKGAYIWDVDGNQYIDYVGTWGPAICGHAHPDVIGALHDALEKGTSFGAPSFLENVLAEMVIAAVPSIEMVRFVNSGTEACMAVLRLMRAFTNREKVIKFEGCYHGHADMFLVKAGSGVATLGLPDSPGVPKSATSSTLTAPYNDLEAVKALFEENRDQIAGVILEPVVGNAGFITPDAGFLEGLRELTHEHGALLVFDEVMTGFRIAYGGAQEKFGVTPDLTTLGKVIGGGLPVGAYGGRRDIMSMIAPAGPVYQAGTLSGNPLAMTAGIKTLELLQKPGAYEYLERITKKLADGLLQVALETGHAACGGHISAMFGLFFTSGPVHNYEDAKNSDTAKFGRFHRGMLERGVYLAPSQFEAGFTSLAHTDEDIDQTIAIAREVLSSILast
1 -54.300PF00202.21; Y2045_BACPE/19-432; Aminotransferase class-III  ali follow..  26  7.................PNLPVVKEEGCYYYGVDGVKYLDFTSGIAVTNVGHRHPKIVQAIKEAADHLTHGPIQYESILKLADELADILPGLDCFFFANSGTEAIEGALKLAKFVTKRPYVVSFTGCFHGTQGSLGVSTSKSKYRKFLQPNGLTEGEVVESLACELLEEEFTNLFKYHVSSEEVAAVILEPVLGEGGYIIPPASWLAKVREICNRHDILLIFDEVQTGFRTGEWFAAQTFGVTPDIMAIAKGIASGLPLSATVANHKLMQQWPLGS---HGTTFGGNPIACSAALATLDVLKEENLLDNAREVGAYARERLNLLKEKYEMIGSIRSVGLMIGIEIID------PQTKKPDGAAVLRILDLALQEGVLFYLCGNEGEVIRMI-TKEQIDDGLDMLQRAL... 414
2 -10.300PF01212.21; LTAE_ECOLI/3-280; Beta-eliminating lyase  ali follow..  18  11.....................................................SRAMLEAMMAAPVGDDVYG-DDPTVNALQDYAAELS-GKEAAIFLPTGTQANLVALLSH--CERGEEYIVGQAAHNYLFEAGGAAVLGSIQPQPIDAAAD-------------TLPLDKVAMKIKPDDIHFARTKLLSLENTHNGKVLPREYLKEAWEFTRERNLALHVD----GARIAYGCELKEITQYCDSFTICLSKGLGTPVGSLVGNRDYIKRAIRWRKMT-GGGMRQSGILAAAGIYALK--NNVARLQEDHDNAAWMAEQLREA....................................................................................... 264
3 -9.030PF00155.21; AAT4_ARATH/29-395; Aminotransferase class I and II  ali follow..  10  1..................PVKLNLSAGTYR-TEEGKPLV---------------DVVRRAEQQLANDLDKEYLPLNGLPEFNKLSTKLILGDDSPALCLSGTGSLRVGAEFLATHNKESVIFVPNPTW-GNHPRIFTLAGLSVQYFRYYDPKS---------------DFKGMLEDLGAAPPGAIVVLQACAHNPTGVDPTFEQW-EKIRRLVRSKSLLPFFDSAYQGF--ASGSLDAAQSYAKNMGLYGERIGS---LTIVCTSEDVAKKVENQVLLVVRPMYLTPP--IHGASIVATILKNSDMYNDWTIELKGMADRIISMRQQLYAALEARGTPGDWSHIIKHIGMFTFTGLSEEQVRLMAKEYHIYMTYDGRIS----------ASLSSKTVPQLADAI....... 367
4 -8.590PF04864.13; TAR2_ARATH/79-436; Allinase  ali follow..  11  7............DPTVYERYWQENGEVTTM-VIPGWQSLSYFSDENNL---FLEPELAKEIVR-----------------VHKVVGNAVTQDRFI-VVGTGSTQLYQAALYALSPHDDSGPVVSATPYYSTYPLITDCLKSGLYRWGGDAKTYKEDGPYIELVTSPNNPDGFL-----------------------------------RESVVNSTEGILIHDLAY--YWPQYTPITSPADHDVMLFTASKSTGAGIRIGALVKDRETARKMI---EYIELNTIGVSKDSQLRVAKVLKVVSDKSFFDHSYDAMYERWKLLKQAAKDTKRFSVPDFVSQRCNFFGRVFEPQPAFAWFKCEEGIVDCEKFLREEKKILTKSGKYFGD-ISMLDRDTNFNIFLHRITSSF... 358
5 -8.530PF12897.7; Q1IZU0_DEIGD/1-422; Alanine-glyoxylate amino-transferase  ali follow..  27......................................LNMQRGQADADFDLSNGLLTVLGAEDVRMDRNYPGGVAGLPSARALFAGYLDVKAENVLVWNNSSLELQGLVLTFA--LLHGVRGSTGPWLSQTPKMIVTVPGYDRHFLLLQTLGF------ELLTVDMQDVDAVERLAGTDPSVKGILFVPTYSNPGGETISLEKARRLAGLQAAAPDFTIFADDAYRVHHLVEEDRAEPVNFVV-FASTSKITFAGAGLGFVASSEDNIRWLS---KYLGAQSIGPNKVEQARHVKFLTEYPGRDHAAIIAPKFRAVDEVLRAELGEGGEYATWTLPKGGYFISLDTAEPVA------------DRVVKLAEAAGVSLTPAGARNLRLAPTRPVEEVRTAMQVVAACIRLA 414
6 -7.820PF03841.13; SELA_ECOLI/83-452; L-seryl-tRNA selenium transferase  ali follow..  13  1.....................VINLTGTVLHTNLGRALQ--------------AEAAVEAVAQAMRSPVTLAGRGHRDRALAQLLCR-ITGAEDACIVNNNAAAVLLML--AATASGKEVVVSRGELVEIGGAFRI---------------PDVMRQAGCTLHEVGTTNRTHANDYRQAVNENTALLMKVHTSNYSIQGFTKAIDEAELVALGKELDVPVVTDLGSGSL--KEPMPQELIAAGVSLVSFSKLL-GGPQAGIIVGKKEMIARLQSHP---LKRALRADKMTLAALEATLRLYLHPE-AEVIQIQAQRLQAPLAA........................................................................................ 295
7 -7.490PF05889.13; SPCS_HUMAN/61-459; O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS  ali follow..  13  1......................................MDSNNFLGNCGVGEREGRVASALVARRHAGSSLLNKITNSLVLDIIKLAGVHTVANCFVVPMATGMSLTLCFLTRHKRPKAKYIIWPRIDQKSCFKSMITAGFEPV---------IENVLEGDELRT---DLKAVEAKVQELGPDCILCIHSTTSCFAPRVPDR---LEELAVICANYDIPHIVNNA--GVQSSIQQGARVGRIDAFVQSLDKNFMVPVGGAIIAGFNDSF--IQEISKMYPGRASASPSLDVLITLLSLGSNGYKKLLKERKEMFSYLSNQIKKLSEAYNERLLHTPHNPILGSMLFTRQVSGARVVPLGSMQTVSGYTFRGFMSHTNNYPCAYLNAASAIGMKMQDVDLFIKRLDRCLK.. 399
8 -7.040PF02347.16; GCSPA_BACSU/3-443; Glycine cleavage system P-protein  ali follow..  12  73.............................................GAGVYDHYQPVIVDHVISRSEFYTAYTPYQPEISQ--QTMICELTGMDIANSSYDGGTALAEAAMLASGHTKKKKIVVSKTVHPESREVLKTYAKGQYIDVVEVPAA---------------DGVTDLDALRQTVCENTAAVIVQ-YPNFFGRIEP----LKDIEPIAHQGKSMFIVSANPL----ALGLLTPPGKFQSDIVPFGIPSAYGGPCGFFAVTKKLMRKVPGRRDKATSNICSNQALNALAASVAMTALGKNGVKDIARQNLLKANYAKQEAKKAGLTVMFDGPMFNEFVIKLDEPVRAVNKRLLA------KGMIGGYDLGLTYPELDCHMLIAVTELRTKEEIDALIQEL....... 441
9 -6.810PF00266.19; CSD_STRCO/31-406; Aminotransferase class-V  ali follow..  15  2.....................................YLD------NAATSQKPRQVLDALSENVHRGVVLAEEATALYEGARDKVAEFPSRDEVIFTKNASESLNLVANMLGWADDPYRVDH---------TEIVITEMEHHSNIVPWQLLAQRTGAKLRWFGLTDDGRLDLSNIDEVITEKTKVVSFVLVSNILGTQNP----VEAIVRRAQEVGALVCID-----------ASQAAPHMPLDVQALGHKMCGPTGIGVLWGRQELLEDLPPGGEMFEAGTPPAQAVGLGAAIDYLNSIGMDKILAHEHALTEYAVKRLLEV------PTTAEERGAAISFTLGDIHPHDVGQVLDEQGIAVRVGHHCARPVCLRYGIPATTRASFYLYSTPAEIDAL........... 376
10 -5.630PF12119.8; Q12JD7_SHEDO/19-235; Protein of unknown function (DUF3581 topsan)  ali follow..  15  9.................................................................NNNNKVVISSQQASDFAKQVAQ-IHDVGAKRFCVPGD--LLFALILTQCGLSKNMTFKFAGMVGDGVELALDPNAGDEFSLSDTRGKTYLNVSRSGDMSRCEVQTEAFIRSYVAFSGLNFIHVLIPLMKARKVM------INPDRPLVIYESMSFHLDTLLASQELAIDGKRGDVTLTFELLSEGKIIGTGKKTLVLSGLREY............................................................................................................................................... 214

FFAS is supported by the NIH grant R01-GM087218-01
1 3 9 5 5 6   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Doctor KS, Reed JC, Godzik A., Bourne PE. The apoptosis database. Cell Death Differ. 2003 Jun;10(6):621-33. Review.