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Query: [J] COG0012 Predicted GTPase, probable translation factor, from COG1018

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MEIGVVGKPNVGKSTFFSAATLVDVEIANYPFTTIDANVGVTYAIAEHPCKELGCKPNPQNYEYREGLALIPVKMIDVAGLVPGAHEGRGLGNKFLDDLRMASALIHVVDVTGKTDAEGQPTENHDPIEDIEFLEREIDYWIYGILSKGWDKFAKRIKLQRIKLESAIAEHLSGIGVTENDVWEAMHRLGLPSDPTLWSQEDLLAFASEIRRINKPMIIAANKADAASEEQINRLIKEGEKRGYIVVPTSAAAELTLRKAAKAGFIDYIPGSSEFKILKDMNERQKKALLMIKEKVLDRFGSTGVQEVINKAVFELLNLIPVYPVQDENKLTDQFGNVLPHVFLMKKGSNPRDLAFKVHTDLGRGFLYAINAKTKRRIGEDYELQFNDIIKIVAVTKLast
1 -32.800PF06071.13; E6TZX7_BACCJ/282-365; Protein of unknown function (DUF933 topsan)  ali follow..  25  1..............................................................................................................................................................................................................................................................................................................................LETYFTA----------GKQEVRAWTIKKGTKAPQAAGVIHTDFERGFIRAEENGKVRLEGKDYIVQDGDVIHFRFN.. 84
2 -24.500PF08438.10; U1I0Z5_ENDPU/226-345; GTPase of unknown function C-terminal  ali follow..  37  1...........................................................................................................................................................................................................................ALNKIDHPDADRNIAKIAK-MQDPQRIVLCSAISEVFLRRLAKQKYIRYTEGAEYVDALKEMDEKLRTRIENLKDMVLYRFGSTGVVQVLGKAA-DLLGLVPVFPVRN...................................................................... 120
3 -20.300PF02824.21; Q9VDV2_DROME/289-362; TGS domain  ali follow..  21  1...............................................................................................................................................................................................................................................................................................................................IRVYT-------KPGAPPDFDDGLILRKGVSVEHVCHAIHRTLAAQFKYALVWGTSQRVGIAHVMADEDVIQVV.... 73
4 -19.800PF02421.18; B3EBA7_GEOLS/7-162; Ferrous iron transport protein B  ali follow..  25  1LVVAVAGNPNAGKSTLINAIAGSRLHVGNWPGVTVEKKEALFDVDGR------------------------SIRLVDLPGCLSPYSQEEIITRDYLVT-EKPDLIINVV--------------------DATNLERNLY------------------------------------------------------------------LTMQLLELGIPMIMALNIFDEAEAKGYKNTRQMEETLGIAVIPTSATRKTGLDQLLKA...................................................................................................................................... 155
5 -15.300PF01926.23; DER_CHLCV/3-119; 50S ribosome-binding GTPase  ali follow..  25  1.RIAILGRPNVGKSSLFNRMCKRSLAI-------VNSQEGTTRDRLYGEIRGWSV----------------PVQVIDTGGVDKDSEDH----KQALAGANEADILLLVVDIRC............................................................................................................................................................................................................................................................................................ 91
6 -13.000PF10662.9; A6TJW6_ALKMQ/1-140; Ethanolamine utilisation - propanediol utilisation  ali follow..  9  3.KVILVGRTGSGKTSLSQRLNQQELIYKK------------------------------------TQAMEFSDRVLDTPG-----IENRRFYYAIISASADCDVIGILQAIDEPNCIFPPIITKIDLEHDSGNVESDLYAAGAQQI........................................................................................................................................................................................................................................................... 120
7 -11.000PF09439.10; SRPB_YEAST/36-221; Signal recognition particle receptor beta subunit  ali follow..  18  5.SIIIAGPQNSGKTSLLTLLTTDSVRPT---VVSQEPLSAA-------------------------DYDGSGVTLVDFPGHVK-------LSDYLKTRAKFVKGLIFMVDSTVDP-------------KKLTTTAEFLV--------------------------------------------------------------DILSITESSCENGIDILIACNKSELFTARPPSK--------------IKDALESEIQKVIERR..................................................................................................................................... 147
8 -10.300PF00350.23; Q582R3_TRYB2/29-205; Dynamin family  ali follow..  18  1..IAVVGSQSAGKSSVLEAIVGKDFLPRGSGIVTRCPLVLQLVQLPRSNKDEWGEFLHRPNKKFFDSSHVLNLTLVDLPGLVMNAVGDQ-IKSMVTRYISPSNTIILAISPANADSSSLQIAKQLDP.............................................................................................................................................................................................................................................................................. 165
9 -10.200PF04670.12; Q9VHJ4_DROME/4-230; Gtr1/RagA G protein conserved region  ali follow..  10  1.KVLLMGKSGSGKTSMRSIIFANYIARDT---TRLGATIDV-------------------EHSHVRFLGNLVLNLWDCGG--QEGFMKQYFAQQRDNIFRNVEVLIYVFDVESQEIERDEALLQNSPEAKIFCLVHKMDLVPEGLRESVFTERMEDLIKLSKPGNVTCFRTSETLYKAWSSIVTMLIPNVAALENSVTHFGNVIEADEVLLFEKATFLVISHCQSKKNRD....................................................................................................................................................................... 216
10 -10.200PF12631.7; D5XDU4_THEPJ/127-455; MnmE helical domain  ali follow..  23  95LKTVIIGKPNVGKSSLLNALVKEKAIVTDIPGTTRDVIEEFVSI--------------------------IPLKILDTAGIRETEDVVEKIGQRSKEALEQADFFLFVVDVASEISSEDMEIAAFLKDLSGIIIANKTDL................................................................................................................................................................................................................................................................. 212
11 -9.890PF05049.13; Q9DCE9_MOUSE/50-412; Interferon-inducible GTPase (IIGP)  ali follow..  13  36VKIAVTGDSGNGMSSFINALRFIGSAPTGVVRTTKKPA------------------------CYSSDSHFPYVELWDLPGLGATAQSVE----SYLEEMQISTFDLIIIVASEQ------SSNHVKLAITMQRMRKRFYV-----VWTKLDRDLSTSTFPEPQLLQSIQRNIRE............................................................................................................................................................................................................................... 176
FFAS is supported by the NIH grant R01-GM087218-01
1 4 7 2 5 8   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Pawlowski K, Pio F, Chu Z, Reed JC, Godzik A. PAAD - a new protein domain associated with apoptosis, cancer and autoimmune diseases. Trends Biochem Sci. 2001 Feb;26(2):85-7.