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Query: [J] COG0017 Aspartyl/asparaginyl-tRNA synthetases, from COG1018

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MKTTIKQAKDHLNQDVTIGAWLTNKRSSGKIAFLQLRDGTGFMQGVVVKSEVDEEVFKLAKEIAQESSLYVTGTITEDNRSDLGYEMQVKSIEVISEAHDYPITPKNHGTEFLMDHRHLWLRSKKQHAVMKIRNEVIRATYEFFNKDGFTKVDPPILTASAPEGTSELFHTKYFDQDAFLSQSGQLYLEAAAMAHGKVFSFGPTFRAEKSKTRRHLIEFWMIEGEMAFTNHAESLEIQEQYVTHVVKSVLENCKLELKILERDTSKLEKVATPFPRISYDDAIEFLKAEGFDDIEWGEDFGAPHETAIANHYDLPVFITNYPTKIKPFYMQPNPENEETVLCADLIAPEGYGEIIGGSERVDDLELLEQRVKEHGLDEEAYSYYLDLRRYGSVPHCGFGLGLERTVAWISGVEHVRETAPFPRLLNRLYPLast
1 -65.600PF00152.20; SYDND_NEIMB/118-567; tRNA synthetases class II (D, K and N)  ali follow..  21  1............................................................................................................SENVRLTNRVIDLRRPVMQRNLRLRYQVAMGVRRYLDAQGFIDIETPMLTRSTPEGARDYLVPSRVHPGEFLPQSPQLFKQLLVAGFDRYYQITKCFRDEDLRADRQ-PEFTQIDLETSFLNEDEIMDITEGMAKQVFKDALNV-----------------DLGDFPRMPYSEAMFKVNDVSNLSNGEDSGLQSPIVKYLSENALKPLWVVDFPMKEGHEDLMVSDPANCLARAYDMVL--NGWEIGGGSIRIHRADVQEKVFAALKISPEEFGFLLDNLKFGAPPHGGLAFGLDRLVTLMTGAESIRDVIAFPKTQ..... 450
2 -12.800PF01409.20; SYFA_BACHD/92-341; tRNA synthetases class II core domain (F)  ali follow..  15  20.....................................................................................................................................TATITEVEDLFIGLGFSVAEGPQIETDKDHPARDMQDSFYFTDELLLRTQTSPVQARTMEKYKKIICPGKVFRRDDDDAT-HSHQFMQIEGLYV-VRMSDLKGVLQAFAKSFFGEER-------------------------SIRLRPSF-------------------------------------FP--TEPSVEVDVSCGICHGDGCRVCKQTGWIEILGAGM------VHPRVLEMSGFNPNEYSGF------------AFGMGVERLSMLKYGIDDIRHF............ 239
3 -10.400PF04076.13; YGIW_ECOLI/25-127; Bacterial OB fold (BOF) protein  ali follow..  18  23..TTVESAKSLDDTWVTLRGNIVERISDDLYVF---KDASGTINVDIDHKRWNG------VTVTPKDTVEIQGEV---DKDWNSVEIDVKQIR................................................................................................................................................................................................................................................................................................................................................. 102
4 -9.720PF13393.6; G2IXI8_PSEUL/10-315; Histidyl-tRNA synthetase  ali follow..  12  9.................................................................................................................................ARQVESAKAAMLELFRTAGYELVLPPLIEEGDSALDIKTFKLDDHLSGRQLGLRADITPQVARIDAHRLCYAGSVVHARPSGLMSS-REPLQVGAELGIEADLEIIELMLATLRQV-IAIFRGLAAAAGLAAEDTRELFGALQSKDIATVRELVAEVAEPYKSAFLALPELYGPRQ-VLDKARTRLPSLPEVELGLMQLTAIANALDGQVELSFDLYAPGWSEALARGG----RYDNVGRKFGRA------------------RPATGFSLDLRDL......................... 306
5 -9.130PF16100.5; I3IYQ1_ORENI/15-142; RecQ-mediated genome instability protein 2  ali follow..  15  38.............SLVWMQGTVLEVQQDRDT--VLLMDETGTFVVQGVNNIPKGK-----PCLSQGKYVMVMGIIQAVSPEP---VIRAVKMADLSELAA.......................................................................................................................................................................................................................................................................................................................................... 114
6 -8.420PF08661.11; Q7Q0T3_ANOGA/1-114; Replication factor A protein 3  ali follow..  14  9.IVNGALMKRHVGQPISIHLKVERADDGCKSFSGKSTDGVNQVQLSDPLNGVCSGWVEVIGIAAPNDTVRGKEIITYFNSGEKTESFDVDGHNML............................................................................................................................................................................................................................................................................................................................................... 103
7 -7.840PF10451.9; Q6FM89_CANGA/3-245; Telomere regulation protein Stn1  ali follow..  11  55.............RRLKFVGTVIGVKKGDDYAVIHLDDSSDSLKCKCEVNQLNSFGIN-INAGFIGSRVEVCGVYNTEFN-----ELEVGFIGVLPSTLFSEIEHWRKCCLLLRM........................................................................................................................................................................................................................................................................................................................... 156
8 -7.660PF16267.5; E6XA29_CELAD/57-142; Domain of unknown function (DUF4920 topsan)  ali follow..  3  1...KYQNLGVADTISTKFSGTVLAVCQAKGCWMNVKLDNGSEAMVKFKDYGF------FVPKDIAGKEVVINGLAFVEEMSVEEQKHYAED................................................................................................................................................................................................................................................................................................................................................... 82
9 -7.050PF17244.2; A0A078HC14_BRANA/408-638; Cell division control protein 24, OB domain 3  ali follow..  8  7.............TGISLYGVVTDILCTGVVFSLKIEDTTGAIWARL------FNSYWSLGRLGLGHVVYVSGLSCKTTKENCLEVLWHEG----EKATFINLSCLPAFLTSSCLHKVSTLSQISKQRKPAINICRVKLDEIDQCHSINTRLSHSVCIDEESPLHGGNLHCSFCRVTFNSNGGSEVVRTFHI-----------ITLADEETTKLYAWCTGQSASAILQISPDEFCDLPEDDQLMYPSSL..................................................................................................................................................................................... 231
10 -6.960PF15490.6; E1BYI8_CHICK/2-117; Telomere-capping, CST complex subunit  ali follow..  10  8..YFPWEINSSEGEALRTFGRLSCYDLARSEAILSTQHGSAQHHVRIDTTLVEPF------EAQLGSLYVVLGEAEHREGESPVIKARI..................................................................................................................................................................................................................................................................................................................................................... 90
FFAS is supported by the NIH grant R01-GM087218-01
1 4 7 2 5 9   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Pawlowski K, Pio F, Chu Z, Reed JC, Godzik A. PAAD - a new protein domain associated with apoptosis, cancer and autoimmune diseases. Trends Biochem Sci. 2001 Feb;26(2):85-7.