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Query: [I] COG0020 Undecaprenyl pyrophosphate synthase, from COG1018

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MKSSTQAVLEHTAIPKHIAVIMDGNGRWAKKRFLPRIMGHKRGLDALENMVKHCAKLGVQYLTVFAFSTENWRRPEDEVSFLMGLFLQALQKQVRRLHENNMRLKILGSRERFNRQILKGIEEAEALTANNTGLTLSIAADYGGRWDILQAANKLIAEGVSEITEDTLAKYLMLGDAPEPDLFIRTGGETRISNFLLWQMAYAELYFTDILWPDFDGKALDDAVASFQKRERRFGRTSEQLPIEQQRNLast
1 -105.000PF01255.19; K9V8M2_9CYAN/27-247; Putative undecaprenyl diphosphate synthase  ali follow..  48  1....................ICDGNGRWAKRRGLPRIMGHKQGVEALKAALRTCNDWGISALTAYAFSTENWKRPQEEVDFLMSLFQVVLRQELREMIKENVRIKFAGDLEALPSSLQKQIYAAMEETKDNPGIQFTVATNYGGRQEILSACRAIASQKADEIDEDVFERHLYTVGVSDPDLLIRTSGEMRISNFLLWQIAYTEIYVTDTLWPDFDRDEFHRALSSYQQRDRRFG............. 221
2 -6.380PF07795.11; I1M4G8_SOYBN/18-248; Protein of unknown function (DUF1635 topsan)  ali follow..  7  1............................................KSMEELRQSLIYTTLELEQTRVAVQEELKKRDEQLLNLKDLLSKTIRERDEA--QEKCQRLLLEKLVFQQQLQHAAPVSGISSIEDEPRRGIDSNNGHSSSDCEESIVSSPVIDHLPQPQPQSMIELTPDKPLPEKGKLLQAAGPL-LQTLLLWR................................................. 161
3 -6.020PF09674.10; G0L2W4_ZOBGA/26-251; Protein of unknown function (DUF2400 topsan)  ali follow..  12  14.......................................................DIEISAFLTATIAWGNRKSIINNANRLMDLMGNSPYDFVLDYRPDDAELSGFVHRTFNSEDLDYFIKSLQNIYINHGGLEAVFAEHA-EEDSMQTAISAFKKTFFELPHPIRTQKHVSDPL--------KGSAAKRINMFLRWMVRSNATSVDFGIWKRISPSQLSCPLDVHSGNGRKLKLLGRK........ 191
4 -5.950PF01261.24; Q7D360_AGRFC/22-241; Xylose isomerase-like TIM barrel  ali follow..  12  61..................................FRAIGEGDVILGFTRMIEASASIGCHELWISPGNFKS-FRTDVTWDEQLQAIEKVLLKLAPVARATGVHLNMETHDEITSFEIMRLIEKIGEDC-------MGVVFDTANGLQRGEHPVYAAKRVAPYIRQTHVKDAYVGRAPGGLDFQTRPVGRGIV........................................................ 220
5 -5.800PF01318.18; CAPSD_BMV/2-188; Bromovirus coat protein  ali follow..  14  4.......................GTGKMTRAQRRAAARRNRWTARVQPVIVELAAGQGKAIKAIAGYSISKWEASSDAITAMSITLPHELSSEKNKELKVGRVLLWLGLLPSVAGRIKACVAEKQAQAEAAFQVALAVA---DSSKEVVAAMYTDAFRGATLGDLLNLQIYLYASEVPAKAVVVHLEVEHVRPTF..................................................... 179
6 -5.770PF17025.5; J9D2N9_EDHAE/18-126; Domain of unknown function (DUF5099 topsan)  ali follow..  18  8...................................................................................................................................................VISRYSEIKANLIKSLKLKYKIEVKILGDKDDPDLIILCSDVLMFYLQDPLILYKAEIWHERR---DFCESTFVYALRHYDECEIRNG............. 108
7 -5.660PF10566.9; Q21N75_SACD2/284-577; Glycoside hydrolase 97  ali follow..  13  1................DVSWVEPAKYVGINENTWGNGPKHGATTANTKYYMDFAAKYGFAGVLVNIGWDGDWYSNGDVFSFTKPYDDFDIAELAAYGKEKGVRIIGHHETSGSVTNYKNQMADAFDLYQKHNVAQVKTGVDENGIVRYEWHDGQFMSREYLRSVTEAAKRKISIN--------IKDTGLRRTPNWIAREGARGQLPFTRML--DFTPGIFDLSFNGLEGENRPRTTLAKQLA...... 261
8 -5.250PF00186.19; Q3XZC6_ENTFC/1-161; Dihydrofolate reductase  ali follow..  16  12........................................................................................................GLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGRKTFEGMGSRPLPNRQTIVLTRDSSYKAEHSVEDVLALEKETDGIFFI-AGGSAVYQEFLLYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEK............... 149
9 -5.210PF17679.1; Q8SDC5_BPDPK/1-273; gp37/Dip protein  ali follow..  15  5........................NITWEEQQALSKLDGHKLEDISVHWVFNPVISVFVTCATMSSHNTHYTFKPQSSPDDAM----------VREYVLSRIIADNLKYVDNLYLAAGAVICGNDEYISDGNVVGIHIADGVGGNKLILPVIEFMPGVHVDDISDKLIKSSSYTDNLEEFEFLVDKKNANNVKELILAYTDYNKLAFKDPAEPAVEMYQFIDRTEVYFSFEGCHPDVEEVL....... 224
10 -5.180PF09623.10; A9WGH8_CHLAA/13-211; CRISPR-associated protein NE0113 (Cas_NE0113)  ali follow..  14  3............................................AVITEAIELLEEQSLHPDGVVLLYTED-----YDVLSSLELLMKHLPAHCEISWIVPISVGTYHDIDSTKAEFMQIACTQLRTYRNNHRLFVSIA---GGRKVMSALLALAVQ........................................................................................... 109
FFAS is supported by the NIH grant R01-GM087218-01
1 4 7 2 5 8   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Pawlowski K, Pio F, Chu Z, Reed JC, Godzik A. PAAD - a new protein domain associated with apoptosis, cancer and autoimmune diseases. Trends Biochem Sci. 2001 Feb;26(2):85-7.