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Query: [P] COG0038 Chloride channel protein EriC, from COG1018

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MAADFETSNRRWLDKLPRNLTDSARSLHPRTLVAAIVVGLITGVLGAGFKSAVNNMLQWRSQLAQILAPIPPLAWLVTALISGGMVALSFWLMKRFAPDTSGSGIPQIEGHLEGKLPLVWQRVLPIKLVGGFLSLGAGMLAGFEGPTIQMGGSIGQMTGGWFKATQENQRILIAVGAGAGLATAFNAPLAGVALIGEEMHPRFRSQTLAYHSLLFGCVMATIILRMIRGQSAIISLTEFKRVPLDSLWMFIILGILFGVMGYTFNRGLFKVLDWFDRLPPLATKWKGFLLGSIIGILSLFPLPLTDGGDNAVLWAFNSQSHFSTLILVFCGRFLLTLICYGSGAIGGIFAPMLGIASIVSVAMARHFHLLFPSQIPEPAVMAIAGMGALVAATVRAPLTAILLTIEMTDNYFVILPLLVTCLVASVVAEALGGKPIYTVLLERTLAKQNRGLast
1 -79.100PF00654.20; A6VKP8_ACTSZ/67-405; Voltage gated chloride channel  ali follow..  20  8............................................................................................IGWYSVHRYGKKLLSVKQGLDNPQQGVPFFKTVGHALLQIITVGLGSPLGREVAPREMSVAFGSAWVRKAGLNDTDAKLILACASGAGLTAVYNVPLASTIFILETMVLSISTR--SLGAALVTVVLSTCVSRFFLGDLVQYDKVTPFAINTELLIFSAIIGMLIPFVVQGFRRSTQHVPFLQRT--DKRIIPVAVLLFSLIGFISIYQPEILGNGKPGNQLTFGEMINWSESLQLMALKWLAVLFALAAGAYGGLITPSMMLGSTFAYSLAIGWNALFP--QLSLEGAAIIGACVFLGIMQKMPFTSIVFLLELTRNAEVLMPLTLAMGAAIATDR...................... 339
2 -7.320PF03553.14; Q9KBE2_BACHD/142-433; Na+/H+ antiporter family  ali follow..  11  1.........................................................................................................................................SLTFGLKAPYILIPAGYGLLFHSIIADEMTANMLFPGLAMVVGLLVAINDAQVDEQSTINETAATEEREFFSLKHVLTLLAIVAALT-------------------VQILFQSLVLGALTGIILMFAFRVVPFHRGDEVMNEGVKMMGTIAFVMLIASGYATVLKET--GAVEQLVASTSSSLGSHSFLIALVLIFIGLVITMGIGSSFGTIPIIAALYVPLCAAVGF----------------PLATAALIGTAGV-SPASDSTLGPTSGLNADGKVPTFLHYNIPLIV........................ 289
3 -6.970PF05505.12; NCAP_EBOZM/19-734; Ebola nucleoprotein  ali follow..  10  5..................................................................................................KILTAGLSVQQGIVRQRVIPVYQVNNLEEICQLIIAFEAGVDFQESADSFLLMLCLHHAYQ-------------------GDYKLFLESGAVKYLFRFEVKKRDGVKRLEELLPAVSSGKNIKRTLAAM-------PEEETTEANAGQFLSFASLFLPKLVVG---EQGLIQYPTAWQSVGHMMVIFRLMRTNFLIKFLLIHQGMHMVAGHDANDAVISNSVAQARFSGLLIVKTVLDHILQKTER-GVRLHPLARTAKVKNEV---------NSFKAALSSLAKHGEYAPFARLLNLSGVNNL-----HGLFPQLSAIALG--VATAHGSTLAGVNVGEQYQQLREAATEA. 332
4 -6.840PF04147.12; S3ECN4_GLAL2/48-905; Nop14-like family  ali follow..  8  452......................................................................................................ESHEQLLEITKGISLLDLPTVVLCNFAISLIDHISYLANQSKLPPFSVLETLIRHIHSLAKSYPKEIANSFRSHLEQFNESRSLSPTPGDLIILTAIGTVFPTSHQVVTPALL--TMGRYLALK-------------IPQNLFDY-----------AVGAYMCTLCLQYQILSKRYI-------PEVISFIENSLCTLAPSRMLILPGNFERSKAEGESLKVALLDTNLSLLGVASETWSGKAS-IFEPSLKI-------LKHLGNKTCRPLLPSNTQKSLTSLTKKITTALSNSVLNLELHHHRPLAIKTSIPKFEETFNPDKHYD--DRDRAEAAKLRKEYKQEKKG 814
5 -6.690PF07235.11; Q8U4X9_AGRFC/2-84; Protein of unknown function (DUF1427 topsan)  ali follow..  19  2...........................................................................................................................................................................................................................................................................................................................................................VYLLSLGAGLLVGIVYS-----LLNVRSPAPPVIALVGLLGILVGEQIIPFARSII................................................ 52
6 -6.670PF05977.13; Q92SW7_RHIME/14-535; Transmembrane secretion effector  ali follow..  13  17........................................................................................IASLASNFGGLIQAVGAAWLMTSISQSVNMVALVQASTSLPIMLFSLVSGALADNFD-AQSFMLAVSALLTVCAYYGIVTPWLLLIFTFLLGCGTALNNP-SWQASVGDMVPRDDLPAAVALNSMGFN--LTRSVGPAIGG-----------------IVAAAGAAAAFAANTLSYFAILFALARWKPVAPENRLPRETLGRAVSAGL------YVAMSPNIGKVLVRGFAFGLSASAILALLPLVARDLVGGGPLTYGVMLGAFGVGAIGGALLSARLREFLTSEAIVRYAFAGFAFSALVTAISPQAWLTCLVLA-VSGACWVLALSLFNTTVQLSTPRWVVGRSLYQTMT.......... 352
7 -5.870PF15484.6; CB074_HUMAN/39-194; Domain of unknown function (DUF4642 topsan)  ali follow..  11  13................................................................................................VPCTDANGGVDCAAAKVVTSNPEDHERILMQVMNLNVPMRPGILVQRQSKEV-LATPLENRRDMEAEEENQIQKIHTSVTRTPSVVESQKRPLKGVTFSREVIVVDLGNEYPT.................................................................................................................................................................................................................................................. 144
8 -5.830PF04018.13; U4K7K7_9VIBR/13-258; Domain of unknown function (DUF368 topsan)  ali follow..  12  1..............................................................................................................................................................................MGAADVVPGVSGGTIAFITGIYDTLLESIRRVNPSIIGIWKREGFKAAFDHI------------------GLFLITLFSGIILSIL--TLAKLISWL------LVEHPIPLWSFFFGLILISVVHVLKQVEKKNIVTGVFLLLGVGFAYTITVVSPLQMSLNIFIAGMIAICAMILPGIS-GSFILLLLGMYGPILAAAKGLQIDVLMLFMLGCVVGILSFSHVLSWLLKNFRDYTLTFLTGLMLGTLPK........................... 227
9 -5.790PF02990.16; C4JNI4_UNCRE/63-607; Endomembrane protein 70  ali follow..  13  271..............................................................................................................................................................................SGWKLVHGDVFRCPKHPLLLSV------LGNGAQLFMMTGLTVLFALF----------LLSPSNRGFLGTAILIIYTFLGFIGGYVASRTYKSF-------EAWKRLIIATPLILPAIIFSVFFFL---------NFILWVKGASGAVPFTTMIVIVLIWFV-----------ISVPLSVGGSWIGFKQPALEGPTIPRQIPPAVGSLRLVPSTLIAGFF--PFAAIFV--ELYFIMNSL--LFLCYGLMIMMSAMTTVLLVYFLLCAED....... 510
10 -5.730PF13782.6; R5EV98_9CLOT/28-140; Stage V sporulation protein AB  ali follow..  8  22...........................................................................................................................................................................................................................................................................................................................................................LYETVIILGGVLGNILDIYEFPIYMGPYIGTLFICVFGLVGIFVGCLVMSLAETLKTLPVISRRIHLAVGLQYLIFALAAGKMAGS.................. 108
FFAS is supported by the NIH grant R01-GM087218-01
1 4 7 4 7 1   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Rychlewski L, Zhang B, Godzik A. Functional insights from structural predictions: analysis of the Escherichia coli genome. Protein Sci. 1999 Mar;8(3):614-24.