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Query: [S] COG2311 Predicted membrane protein, from COG1018

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MERNVTLDFVRGVAILGILLLNISAFGLPKAAYLNPAWYGAITPRDAWTWAFLDLIGQVKFLTLFALLFGAGLQMLLPRGRRWIQSRLTLLVLLGFIHGLLFWDGDILLAYGLVGLICWRLVRDAPSVKSLFNTGVMLYLVGLGVLLLLGLISDSQTSRAWTPDASAILYEKYWKLHGGVEAISNRADGVGNSLLALGAQYGWQLAGMMLIGAALMRSGWLKGQFSLRHYRRTGFVLVAIGVTINLPAIALQWQLDWAYRWCAFLLQMPRELSAPFQAIGYASLFYGFWPQLSRFKLVLAIACVGRMALTNYLLQTLICTTLFYHLGLFMHFDRLELLAFVIPVWLANILFSVIWLRYFRQGPVEWLWRQLTLRAAGPAISKTSRLast
1 -58.900PF04235.12; A5UQH7_ROSS1/237-401; Protein of unknown function (DUF418 topsan)  ali follow..  29  1......................................................................................................................................................................................................................FGKRQIFQRLNEKPASERRLPAGSVCLAVGLIANLALAWQVTDLSSPLAGLWSILTLIAGPVLSYGYLALFVTLTRTDAWRRRLQPLAAAGRMALSNYITQSIICTLIFYGLGLFGQVGAFIGLVISVTIWLVQLGVSVVWLKRFRFGPLEWAWRSLTYGK.......... 165
2 -23.000PF07786.12; A1HQT7_9FIRM/5-214; Protein of unknown function (DUF1624 topsan)  ali follow..  15  1..RIWEIDALRGLAIVLMVVFHLVV------------DLKDFYGAKLEYLSGFWFWVGRSSAVLFMLLSGVSTVL-----GRRPLRRGMAVFAWGMVLTAITYRFGILHLLGVSMLLGHGLRRFHPAIVTIIAFAFLALGQLAKTNA-------------------------------VSHSLFLPFGIMPENFTSLDYYPIFPWTGVFLLGYALGRTVYKRKMSRIPG-----------------------------------------------------------------PPRFIWLTTLGRRSLFIYLIHQ..................................................................... 209
3 -16.700PF10129.9; A4YYN0_BRASO/36-389; OpgC protein  ali follow..  11  1..RDLRIDACRGLALWFIFVDHVPDNSLAWLTLRNYGFSDTSEV--------------------FVFISGYTCMLAYGGTAVRALRRAWEIYAAFLVLLLAYA--DILLTFAILHICVLWLMMTSATATLAVSFVLYMMV-----------------------QLFSWQVPAWPSGELYFNPYAWQF--------------------LFVIGAWYAYGGRQRLRPLLYSRTLLIMALAYLGFSLLMALSWEFKSLESLLPQAIAALIYPIYLLHFLALAFVVSRLAPPQWHGPIRPLMTAMIRCGENSLSIYCIGVLLAFIGQVVLTDVASGFAMQLLISVIGIAVMVFA................................... 345
4 -15.800PF16401.5; G8TDM1_NIAKG/23-280; Domain of unknown function (DUF5009 topsan)  ali follow..  20  1..RNKSLDALRGFAILAMVLSSSIAFCILPAWMYHAQTPPPGHVYTP---ELPGITWVDLVFPFFLFSMGAAIPLALHKKVKEAIRRFAGLVFFALFTMHA----YVLQLVSFVLLFFQWYIPANTLYKNRWLVIRTLAFAGAGCLLLF............................................................................................................................................................................................................................................ 161
5 -13.400PF01757.22; OPGC_SHIFL/9-357; Acyltransferase family  ali follow..  11  4......LDSIRAWLMLLGIPFHISLIYSSHTWHVN-------SAEPSLWLTLFNDFIHSFRMQVFFVISGYFSYMLFLRYPKVRVERVGIPMLTAIP----LWFLLVLVVMTTLCVWIFKRIRNNLENSDKTNKKFSMVKLSVIFLCLGIGYAV------------------------RRTIFIVYPPILSNGMFNFIVMQTLFYLPFFILGALAFIFPHLKALFTTPSRG------CTLAAALAFVAYLLNQRYGSGDAWMYETESVITMVLGLWMVNVVFSFGHRLLNFQS-----ARVTYFVNASLFIYLVHHPLTLFFGAYITPHITSNWLGFLCGLIFVVGIAIILYE................................ 349
6 -10.200PF05857.11; Q326X1_SHIDS/32-247; TraX protein  ali follow..  17  3.......DIIKTVALVLMVLDHINLIFQLKQEW---------------------MFLAGRGFPLFALVWGLNLS-RHAHIRQPAINRLWGWGIIAQFAYYLAYEGNILFAFAVAAQVLTWCETRSGWRTAAAILLMALWGPLS.................................................................................................................................................................................................................................................. 121
7 -7.720PF12823.7; A0A1N2QT25_9MYCO/11-100; Domain of unknown function (DUF3817 topsan)  ali follow..  22  1..........................................................ASRFRTVALLEAVSWAGLLTGMFFKYVPDPIGVKVFGWIH------GIIFIAYLVVAFLAGREYRWKPLTWLLALLAGVA....................................................................................................................................................................................................................................................... 77
8 -7.200PF02990.16; C4JNI4_UNCRE/63-607; Endomembrane protein 70  ali follow..  13  223...VILLVALVSTILMRALRKDIARYNINLDDLNDNPSSVEDGIQEDSGWKLVDVFRCPKHPLLLSVLLGNGAQLFMMTG-------TVLFALFGLLSPS---RGFLLIIYTFLGFITYKSFGGEAWKRLIIATPLILPAIIFSVFFFLNFILWVKGASGAVP---------------------------FTTMIVIVLIWFVISVPLSVGGSWIGKTNQIPRQIPPAVGSLRLVPSTLIAGF-----------------------------------FPFAAIFVELY----------------------FIMNSLWTGKIYYMFGFL----FLCYGLMIMMSAMTTVLLVYFLLCAEDY---RWQWRSF.............. 518
9 -7.050PF15717.5; I3JV64_ORENI/1482-2091; Pericentriolar material 1 C terminus  ali follow..  9  1..........................................................SSDFSLFETLYSEVATLISQNESRPH-------FLIELFHELQLLNTDYLRQRALYSLQDIVSRHLAERSA----------QMPRLGPAVWAAGSQSELTPSESLTTSDAEVVEKNLRITQDTMKKRDDADSVDNDSTMSTSSNLEPFANDDLGNTVIHLKALARIREYERMKLKAEFNPCSASTAGAGTSDVSNAERPANPAEHLEGAAGGEVHCPQIDTQQLDRQIKAIMTEVIPFLKENMDEVCSIQLLTSVRRMVLTLT................................................................ 254
10 -6.830PF14965.6; H3AVH4_LATCH/34-216; Negative regulator of p53/TP53  ali follow..  17  51............LDVLGVDASNLTHYFSPTAVTSNPTRAVLLVGAVLLAYWFLALFI-GVLFSLLHAVFGRMFWIV-----------RVILFALSCLYILQKHEGNVVAVYFMTGPVALYRRRNSSTL................................................................................................................................................................................................................................................................. 164
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Friedberg I, Godzik A. Fragnostic: walking through protein structure space. Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W249-51.