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Query: [V] COG4452 Inner membrane protein involved in colicin E2 resistance, from COG1018

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MLKSPLFWKMTSLFGAVLLLLIPIMLIRQVIVERADYRSDVEDAIRQSTSGPQKLVGPLIAIPVTELYTVQEEDKTVERKRSFIHFWLPESLMVDGNQNVEERKIGIYTGQVWHSDLTLKADFDVSRLSELNAPNITLGKPFIVISVGDARGIGVVKAPEVNGTALTIEPGTGLEQGGQGVHIPLPEGDWRKQNLKLNMALNLSGTGDLSVVPGGRNSEMTLTSNWPHPSFLGDFLPAKREVSESGFQAHWQSSWFANNLGERFASGNDTGWENFPAFSVAVTTPADQYQLTDRATKYAILLIALTFMAFFVFETLTAQRLHPMQYLLVGLSLVMFYLLLLALSEHTGFTVAWIIASLIGAIMNGIYLQAVLKGWCNSMLFTLALLLLDGVMWGLLNSADSALLLGTSVLVVALAGMMFVTRNIDWYAFSLPKMKASKEVTTDDELRIWKLast
1 -115.000PF06123.12; Q8E9F0_SHEON/61-487; Inner membrane protein CreD  ali follow..  29  1.....TLLKALTIGILSILALIPLGIIMDLTSDREMLYHSVVEEIGRSWGEQQTLSGPALVIPYRYFVMEEEVSNDVKRTYQDELVILPKKLALDLDLKHDFRTRGIYQSLVYSAALKGQADFSLNSYDIPNLIALDNKNARLVFGVSSNQAIDKVEKIEIKGDSALLSGSLMSGTGLTTKGFNQGIQVSEASDFSVNFAMTLRGSQSISALPLGEQTLINIQADWPHPSFKG-LLPAEREINAKGFTASWNISHLTRNYPQEFVKSN-QSTLTEVVANAILFEPVTHYGKIDRSVKYGLLFIVLTFIMLFIFELGQKTSLSIVQYILVGSAMALFYLLLLSLSEHLAFLQAYLIAACIPVLSVSTYVGSATASLKRGVIVGTMLVSLYAVLYSILQLEDYALLMGTGLLVVVLLILMFVTRH........................... 426
2 -10.700PF14667.6; E6U1Q3_BACCJ/375-523; Polysaccharide biosynthesis C-terminal domain  ali follow..  14  3.....................................................................................................................................................................................................................................................................................................KYYAPVAILFSIFAVTSSLLQGINRQRY-AVIALLAGLIFLTFTYLMIVWLGPAGAILATGVGYVIAIGVNVWAIGRLLLIVMFASLMALVVFLVRNLIGAILPLETWINGATILFTSIVAGLLTYG.............................. 141
3 -8.900PF07457.11; U5L9U3_9BACI/2-108; Protein of unknown function (DUF1516 topsan)  ali follow..  14  9...........................................................................................................................................................................................................................................................................................................VVALVLFFAALGMHNSGKAKGVKVVQMIL------LFYLLIIGLTSGINIDLLYVLKALLGLWVIAMIEMIIIRTTKGKKTSILWVQFVVAAILVIY...................................................... 105
4 -8.200PF15971.5; D2RW44_HALTV/57-219; DolP-mannose mannosyltransferase  ali follow..  13  14..................................................................................................................................................................................................................................................................................................................................PVPFAITAALAVLS-------GNMYVLHGLSVILTLLVAAANILLVGWVAFLVTGEDAAAVAAGLTMLVVPELFLLPLAGVWAQFYALFFGVLSLALALRD........................... 108
5 -8.040PF03208.19; D7LLJ1_ARALL/49-193; PRA1 family protein  ali follow..  17  17........................................................................................................................................................................................................................................................................................ALSKPESISDAAVRKVNYLTVATAIVGFSLVT---------HPFSLVFLLCLLASWLFLYLFRPTD-TFSDRETLGCLILFSIFVIFLTDVGSVLVSAMMVGVALICAHGAF.......................................................... 134
6 -7.920PF14184.6; R6V4V5_9FIRM/10-136; Regulatory protein YrvL  ali follow..  12  1.....................................................................................................................................................................................................................................................................................................EKIITLLLCGVLLIIVLSVLALISGMKVFGFEYRSIG-SIILFFIIATIISYPLGLIAGALPKALLSLDKVSMPTAITLYLILDTFATFWGLRITDYCMQSISAEDISIFVISLIFAFLGV.................................... 122
7 -7.920PF12428.8; M0SAU6_MUSAM/200-316; Protein of unknown function (DUF3675 topsan)  ali follow..  16  1....................................................................................................................................................................................................................................PGYTAPQKLFQYGSIPMNFRGNWEITRQDLNDSQILTLYPSERDVMHPHD--------DDYSALGMRTTVCCQSVAIIFMVLLVLR-------HTLPLAISGAEQYSFTIFSLLVLRTAGILVVFVLIRTI........................................................................................... 117
8 -7.740PF00892.20; YDED_BACSU/160-296; EamA-like transporter family  ali follow..  5  8............................................................................................................................................................................................................................................................................................................VLSGFAAAFYTLYAVGLLNKFDSLVVVGWAMIIGGFALGFIHPPWQLAYAYILFVILFGTMIAFWFFIKSLESLSPKETSLLGSLEPLSAVVTTVVWLKAPFGSFQWIGAICIIGITLILA............................. 136
9 -7.720PF17178.4; I2B9L9_SHIBC/27-213; Membrane-associated sensor  ali follow..  11  45..........................................................................................................................................................................................................................................................................................................MCAIMVASVALSIVCYRFQALSLSLSMVLLLAIGLMWSYSCYYFIVWWHLPSGWPLMVILMLSALAALYYH------PRALLLFLFPLWVAALVFGTWLNPGARGH--FLLMWILLTATLAGGWYIRWFSEAWYRYQENR............ 178
10 -7.460PF07695.11; Q72MW7_LEPIC/129-333; 7TM diverse intracellular signalling  ali follow..  11  9.........................................................................................................................................................................................................................................................................................................FGILIAMAVYNLFLLLTVRDKSYFF---YVFYILCFAIFLMSQYGFAYEY--RRMNPFLAGLLEFSILLFTRDFLDTKNTFLIILCAMASFSSFFVNLTQGALQVAILGLLTAISILASGIKALMS........................... 147
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 3 4 1   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Jaroszewski L, Slabinski L, Wooley J, Deacon AM, Lesley SA, Wilson IA, Godzik A. Genome pool strategy for structural coverage of protein families. Structure. 2008 Nov 12;16(11):1659-67.