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Query: [A] KOG1295 Nonsense-mediated decay protein Upf3, from COG1018

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MSSKDIGEVVQFRDRFDGYVFVDHKGVEYMAIVEYAPFQCFLKNKARNDDSKVNTIESEPHYQEFIKRLAQEREEASRMGDVKIDFNFERRTEEKVKSTPLLQYLANKKEKRREEARRRNEEKRKQREEQKLLRLAAQSDASKLKEAEGGGGGGDTKKPAKKDVKDPQSSGSQANDAKASRSKRRTERDQRRREEHEQRKLVKRDKKKDDGQGKQDKQDKQDKGKPSSGKQNKNSKSMDIVILKKANKPESNESLDVPSTSNAAEASKEKPATENTETPEAAVKVFTPAARGGRKEKRTGADKQPAGSAHETAEEAIKAAQFRASEERRIRNKVGLTYYPPRHFTNPLDVYRIDHRLPFTSPKPEFVHQMSCPKVQAAKMARMERLPWWRRRLRRGTNAPIGATNPNRRRLast
1 -39.600PF03467.15; S2K0L0_MUCC1/59-241; Smg-4/UPF3 family  ali follow..  30  58FHFKTMEAVIAFHQGYDGHVFVDSRGNEFRAVVEFALYQKIPKEH-KTADARQGTIDQDQDYLDFLESLKEEEKAQSNRIAMVTAKTLAAEQANKPKTTPLLEHLRAQKA............................................................................................................................................................................................................................................................................................................ 183
2 -13.400PF04059.12; AML2_ARATH/679-775; RNA recognition motif 2  ali follow..  17  50INMVSPLHIVPFQQTFNGKIWEK-FNSGKVASLAYAEIQGKSALASY........................................................................................................................................................................................................................................................................................................................................................................... 95
3 -7.210PF15376.6; F1QJT2_DANRE/24-1319; Domain of unknown function (DUF4603 topsan)  ali follow..  5  74.....................................................................SKRKGGTDLSLEEMKKQAAVQCLRSASDENSGIESLVEELCSKLKDIQNKQKEKEKHGIKKSDISQSPEPDESLSSKDQVEMYYEAFPPLSEKPVCLQEIMTVWNTAKACTYSSSSSSAVPQTSTDTSSPKDCTSEGEAFKDRTVDAPSSTSTTSEKAQQRRTKREKENRFHGSATGMPDDQVAPHSKRQARHRSEGRFRPRSWSSGSSEAGSSSSGNQGDQAPSCKSVRIRHKSREVSGRNKKGRSGGGQVKLALKVIDKEERKNARGNMSTTGGPPKQQQHYMKKGKRPLREIRKDANLVEAQESGGEASKKEYMEE...................... 392
4 -7.160PF13962.6; B9I096_POPTR/412-520; Domain of unknown function  ali follow..  16  1..........TYKRMGNTLLMVAT----LIATVTFAAAFTLPGGFNNDLGLKQGVLESSKHLRWFV........................................................................................................................................................................................................................................................................................................................................................ 54
5 -7.050PF13779.6; D7A9C0_STAND/55-942; Domain of unknown function (DUF4175 topsan)  ali follow..  7  524.........................................................EDGDLSDVEKKLRDAQQALQNALENNASDDEIKRLTQELREA-MQEFMQALAEEAQRNAQADSDQPMGPNTRMVRPQDLQKMLDRIEDMARNGARDAARQMLSELQNMLNGLQAGRQQQRRQGQNQMSQAMDQLGDMIRRQQQLRDRTFKQGREQGQQGEQGQQGQQDQRFGDLKQSQEQLREQLRQLREKMQQAMRGRQQGQGEQGQQGQGEQQGQNGQGQQGQQGEGQQGQGMPGEGGLGEAEQAMREAEQALGQGDGTGAVDAQSEALQALRKGAQQMAEAMQQQPGQGQGQEPGGPSGETAERNDPLGRPMRSRDYGDDVTVKVPDEIDMQRARRVLEELRRRFGEPER 875
6 -6.760PF08507.10; J8Q3G4_SACAR/6-135; COPI associated protein  ali follow..  13  49LEFKVPPNIASFYFSFLGYILLGL-GVAF-IVFHFSQ--FVEEPANFRAPGSSLSIGDDD.............................................................................................................................................................................................................................................................................................................................................................. 130
7 -6.690PF12822.7; B0RZQ4_FINM2/7-171; ECF transporter, substrate-specific component  ali follow..  9  12INCLGAFIAVSTK------LLLDHIGSLLVCML-FGWKYGIVTAFLSS----MNQILFDPFALPFA------YEKGYFKKLHTIPALLLAVLPGAILGAIIQGYIFGGVTSSGSDVIVRFMINKGVN........................................................................................................................................................................................................................................................................................... 137
8 -6.570PF06939.11; Q971Q5_SULTO/1-112; Protein of unknown function (DUF1286 topsan)  ali follow..  7  30........FIAAYSSILGNSLIDRLGHRELLTGRGYIPVRSPLTHTYPRSVLWGLLPTIP.............................................................................................................................................................................................................................................................................................................................................................. 81
9 -6.400PF13631.6; Q4JWC3_CORJK/115-288; Cytochrome b(N-terminal)/b6/petB  ali follow..  14  18.AFRKPRELLSVAEGFMGYSLPDDLLSGVGLRIMSAIMVGLPVIGTWLHWIMFAIIPR---LIPGILLALIAAHLALVWYQKHTQFPGPGRTENNVVGVRILPVFGLKAA............................................................................................................................................................................................................................................................................................................ 147
10 -6.390PF15717.5; I3JV64_ORENI/1482-2091; Pericentriolar material 1 C terminus  ali follow..  6  313............................................................................................................QDLDNSTGIALAAKHKNKNRAEQNSKAKHSQKNNTAGGGDKSLSPAYTDEDKDQDEAEQEGASASQELYLQTQMKNSRSSEASEAEEDNEDEEGGREVPLSISLSKAETQALTNYGSGEDENEEEEIEEFEAGPVDVQTSLQASADGQAEQESTAAGTAASEAEEIRTEQRSSENDDEIVRSVETVDSGVEEHERVECQSPEEESKAGASAVASERESTMYQGQDVTKEAPTTSSPDTDSPVMISVDEVGSGNTSQKSDEDDFVKVDDLPLQLTVMCEEELQKRIVEEQQNNNLSVE..... 609
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 2 6 8   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Friedberg I, Godzik A. Fragnostic: walking through protein structure space. Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W249-51.