current user: public
If you have questions about the server, please let us know.

Query: [S] KOG2172 Uncharacterized conserved protein, from COG1018

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
    .   10    .   20    .   30    .   40    .   50    .   60    .   70    .   80    .   90    .  100    .  110    .  120    .  130    .  140    .  150    .  160    .  170    .  180    .  190    .  200    .  210    .  220    .  230    .  240    .  250    .  260    .  270    .  280    .  290    .  300    .  310    .  320    .  330    .  340    .  350    .  360    .  370    .  380    .  390    .  400    .  410    .  420    .  430    .  440    .  450    .  460    .  470    .  480    .  490    .  500    .  510    .  520    .  530    .  540    .  550    .  560    .  570    .  580    .  590    .  600    .  610    .  620    .  630    .  640    .  650    .  660    .  670    .  680    .  690    .  700    .  710    .  720    .  730    .  740    .  750    .  760    .  770    .  780    .  790    .  800    .  810    .  820
# Score Template Links and tools%idFirst MGGGEKRKSSFKNLANAKKRRTGPHLPSSILKTIANEKRPLNSDEGDDEIDSAYGDFYEYEEGVPEEESRKNNRYERVVNYEFELAEDCEDENVESEDDDDDDDDDDDDRHSRMLKNVTELPISAFQGESKNKRVVFTEPYPESEFNPTRDVLEGKSLTTIDDFMEPLQGLHGNSQLSNMISRMRKDTQSLVHAPLPKPEQERLERDVANELVYKGFDIWVPLVKRNREAPTIYFNQDVNVGYSTVGAIASQFHPRTEFEMKMASLLDDHEILEAHKEDGARLLEFNEVSMEDHIKRRNHVAKMRSMLFRVDLKHKRIKQIKSKTYHRLKNKDLNQSGVGAFMEPAMAKEEAKKQEARRVKERMTLKHKNTGQWAKRMLSRGLNRKYDVTQAALSKQLQIHATLSRKMNSTKDESSSDEEDLNDGSDQDTSKLIAEAKEKILKTVDDDEVPISRLMSLPFMARAVKKKNEEAKEEGKRDIEELEKFGGAETSKKSTNVVGRRVFGAEAPKESEKESDNLFDNSDSSDNDMEDNELEAVKDNASPARNTETIMEAEKLDDIAGNPASKTTFDVALYASGSWKKMTGCKNAESKKASKTHVPISQSQDKKESSDSESDDSESDDSESEAEQMVDGILTCGSKETYEIPCQAELVSRAFAGDDVEGDFEKDKQEVLNQEVPEPEKPVQVAGWGHWTNNQNKRGLPSRIVREHEEAKKTREQALRKRKDASFKHVIISEKVDKKAEKLQTKSLPYPYTSKEVFEQSMRMPIGPEFNPTTIVGVLNRPEVVKKAGVIIKPVKFEEVNPNDEHPRSHQKQKPKKKGGKLast
1 -147.000PF04615.13; H0ELH1_GLAL7/212-958; Utp14 protein  ali follow..  19  1......................................................................................DEESEEESSASSADEDDETSDPAKIAALQSLIANLPQADESAKAPAKQRQDGASEYAAP---SDYGLTPKTKLTLEDLGLPGISDPQIRKSLKYVEQDAKKTQAKLEVPLARRQQDRLDRSSAYDQTKETLARWTDTIKHNRRAEHLMFPLPDNDHSNKQLVPTAQTKPFNELEAAIQNILEESGLATEDQIREYEELETKNMSIDEVKAKRAQLRMARDLLFREEAKSKRIKKIKSKSYRKVHRKQREKEERLAEGGYVASEDELEAQDRRRANERMSAKHRG-SKWAKATKETGRAAWDENARSGITEMARRDEELRKRVEGRAVRKEFDNGSDASSSDSDQDDSDDEERKVTGSDIISESAPGGKLANLKFMRKAEEARKKENDAMVEDIRREMAGEGSSGEEEEAGDIAKPKSLPENEFEEPKGSDDENDEMELDVQGVDNSSKPTSVSKNKKKDAQKTKVLSSSIVPDLVASEGGAWSKVPIRKSTTVNDAEAMRRRHKKNEAVEIGELDLAAAAMVATQTKPKKSRPQSSVTFEKGVESDESGDENTVELPFAIRDQDLIKRAFAGADVVGEFEAEKKQTVEDEDDK-IIDNTLPGWGAWTGDGVSK--REKARNKGKVLTKVAGVKAANRKDAKLDRVIINEKRVKKNGKYLAFALPHPFETRAQYERSLRLPVGPEWATKETLQAATKPRILLKQG-IIAPMSKP....................... 747
2 -7.800PF15324.6; H9GLI0_ANOCA/127-1404; Hedgehog signalling target  ali follow..  9  1..................................................................................................................................................................DIFISQYDAGQKEAVRAVFKQRVQ------NAPVFKEVKVQLNKKDSPKSSHSEMDSAATIAAATAAAIASTAPL---------------LKVQSDFEAKVSSVLQETDRRLQLAVERQSSLKAPTRERSPCHQRFGELEKQMHLFM--EQRLRNLENFQQQQ--NIQSHLISSALNPGGLQAASTAASKETTKPTAGRSLASQTSPPQDLLAARAVHMQACSRPFGSHAVHRQKSPLNTPAPRRYAPVPVSRDAKISQKMSKREPPVGEKENMHQPAYGTTVGGGKLLEQILNSQETPASQDTYSLKESSGNNAVLWPFERECRSSVQEPEPFCAFKSTNQNLNPVERTVQKAGDVLRDLGQLKREMHDILQDAKEWKSDMNKFMKTTAHPGEAIQAKDRLPQSQSSSSLLPSSEAFLPMPPPAENYTVAPTLRELQQLSKSSILQSTQASKSILRDAEKILRAVQKNKKLLEENLEAIIRAKDGNALIDGLTADRDVLEEIRIRKSMEIQDEMERTDS-----------------LKRQQASQMARTSREIMGKSHYPSKVPTKRPLPATKPIQRLTDKVLPKTRL---LHNEDFLSQVRSP---RFNSPPPKSKPPRPKVIESVGTKVKSARTQT...................... 633
3 -7.670PF09586.10; Q839W8_ENTFA/19-846; Bacterial membrane protein YfhO  ali follow..  9  439.................................................................................................................................................................................................................................................................................................................NTRAMVTGILDDWNYASRSLYSEPYPDLKNLVDQTKKENDT----RLENLNGVSANDGINYGYSGISMFSSVR---------NRHSSTYLNALGFRSRGTNLNIRYQNNTLLMDALMGIKYNIAENNPMKFGFERQAAAGKYQLYRNENALPLGFLADKEIYNVRQPLNDNLGSQTNL------------------------NALANTNERYFTFYQPTMTLQNNVTITQNTAGVTFTEKQHNVAKEISYTVNVPANTQAYLSLFPTDFAQLESSTATVTVNGSSQQSQIGITGQYYNLGYYPKDTTVNFKVSFYGTKAVSFVQPQVVGLNTNAFEKAISAVQEKGVDLTTGKRSASGTFTADKDQVL----------TTIPGW----------------------------------------RVKIDGKKVT------PKAFKDAFL-------SVPVSAGTH----TIQFSYLPEGL--IPGIVL............................. 827
4 -7.160PF09726.9; H2MT57_ORYLA/2-679; Macoilin family  ali follow..  10  255..DGRGGGEAKKQHNSNNILQPSLDSKIHEMEYMENHMNKRLTTELDSTESLLLKEDNNSSCSSSSSSSSKNYKNASSNAAALNSSPRGHSTTNGSVAFSASSSTTNTAKNDKKHKLPVGKGTAGGSHKDPADNWIPNNQLSKPEALVRLEQDIKKLKADLQDLRSQISSLGSAERSIRTELGQLRQENELLQNKLHNAVQAKQKDKQTVGQLEKKLKG-----QEARATAEKQLAEEKKRKKLEEATAARA-RRITELETECKKLTMDIKLKEDQLEIKVQELHKYKENEKDTEVLMSALSAMQDKTQHLENSLSAETRIKLDLFSALGDAKRQ--------------EIAQGQMIQKDQEIKDLKQK..................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 629
5 -7.050PF04931.13; K2SXE2_MACPH/89-879; DNA polymerase phi  ali follow..  10  632...............................ESMSGQQDLFDQQGSEDGEDASEDDEDEQDSDVEMVEADGSDVEEVEEASDVDEEEEEDEDEEGGEDGSDADDEELEKFNAALAKTLNT---------------SMLTGEGEDSDDDDEADMDDDQMMALEPHLTKIFKQRQEAANKSKKKDNKDAKATMIN..................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 778
6 -6.950PF13779.6; D7A9C0_STAND/55-942; Domain of unknown function (DUF4175 topsan)  ali follow..  8  385..............................................................................................................................................................................................DFPLPLSGGRARTATGQTTKDLAES----WAGT--------TMTLVARDEAGNIGRSRPRTFVLPERSFSNPLARALIDERFDANQRERVEAGLDALAIAPEKFTPDPSHYMGLRSAYWRNAKSDEDLRGVVAYLWEIAVRIEDGDLSDVEKKLRDAQQALQNALENNASDDEIKRLTQELREAMQEFMQALAEEAQRNAQADSDQPMGPNTRMVRPQDLQKMLDRIEDMARNGARDAARQMLSELQNMLNGLQAGRQQQRRQGQNQMSQAMDQLGDMIRRQQQLRDRTFKQGREQGQQGEQGQQGQQDQRFGDLKQSQEQLREQLRQLREKMQQAMRGRQQGQGEQGQQGQGEQQGQNGQGQQGQQGEGQQGQGMPGEGGLGEAEQAMREAEQALGQGDGTGAVDAQSEALQALRKGAQQMAEAMQQQPGQGQGQEPGGPSGETAERNDDVTVKVPDEIDMQRA---RRVLEEL---RRRFGEPERPRLELD........................................................................................................................................... 881
7 -6.950PF09335.11; Q03TB7_LACBA/75-190; SNARE associated Golgi protein  ali follow..  12  1.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................VPIFGRWPGFGITLGNLLAIYLMSQFPKRSKPSRFQYLTDK------LKTMRHPRLGLSIGYAIPLPTVLVNYTALELRPSF-ATTFSCIVMGSLPVSFLYAFGGD............................... 115
8 -6.660PF13536.6; YJLA_BACSU/38-305; Putative multidrug resistance efflux transporter  ali follow..  12  56..............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................PGWGTWAGVLLSPLFYVKQDMPGGPQLIRQKI---PLVSLGTSVIILQHAESLSGRMLLFSVLPYPLGNRDTFQRVLGMTLAPFWLILAAWWSDGLPTVAVSSGIIATVLWATDMVRDNPQKLAAVEATQSGE... 233
9 -6.560PF17692.1; G7PY63_MACFA/1-128; Family of unknown function (DUF5538 topsan)  ali follow..  12  3.........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................LKVGFQGGGS-GGVSARWARAPHSAPLRPPRELHAAPPSAT------TQTVMRPAGFPRRTRLMVRSAP-P---------TQRPPTGSGCVSGLWRKGLLRPQTLLRVGGVVAPALRPRL..................... 119
10 -6.300PF02682.16; Q7CTL7_AGRFC/1-191; Carboxyltransferase domain, subdomain C and D  ali follow..  10  65............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ASRDLSAKIAPSDNLVEIP----YDGEDLADVAELTGMSVEE---------------------VIRRHTESEFTVAFCGFAPFGYLV--GGDPALHVP------------RRQSPRTRIPAGSVVYPQNSP....................... 167
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 3 4 1   jobs submitted since Jan 1, 2011
Comments and questions to: webmaster
Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Jaroszewski L, Slabinski L, Wooley J, Deacon AM, Lesley SA, Wilson IA, Godzik A. Genome pool strategy for structural coverage of protein families. Structure. 2008 Nov 12;16(11):1659-67.