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Query: [K] KOG2181 LIM domain binding protein LDB1/NLI/CLIM, from COG1018

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MCVVIFLKFLFSDNGNNQHGTEAAFGRLAQSYRIQDLLFIIVIFFRAIHIMMFHRPPSARPPLNHVDQLKSLQATALGKPGMRSQATEPQPIGNTVSPLEFRIHDMNRRLYIFSSTGVSENDQQQWWDAFSHEFFDDDCKLWFVIGSEPVAFASRERYIINRQFIPKFFRSIFDSGMRELQYVLRGPSRECTLANGSQAYENENVLQITRYDQSSQFEVNTEGKLYVEFAPFDEVMNYRIKAWTLELKRSNEFVYNQNTADYRVEAQNPEQENKPRMGFFKSTFNLMTMLKILDPMQSIMSSAKSAPAITPREVMKRTLFQHHQVRQQNMRQQQLNQQMMIPAPEPEKPKPARKRQRKPAANPRGSKKATAAAAAAAAAATNGVPPTVPTASPANNQQFPPNPMTSQFQQMSYPDVMVVGEPSMMGSEFGENDERTISRVENSQYDPNAMQMQSLGQGPNSSMNINGRNMMNQHHPGMQPPPGQQHMPPHSMGSQMPTSMHNPMHMPPGSMQGHGGMPPMPSTMANQMPPPNLPPHTMSNQMPNSRMPPMQGQMPPSGMPGQMSNPNMMGSGMPPMSMSSQMPGSMSNPMPNQMPGGMQMNQMPPPNYSQYTGGPPPQWPPPNSAMITGLast
1 -35.700PF01803.16; K9GGX7_PEND2/375-597; LIM-domain binding protein  ali follow..  16  1....................................................................................................LTIHAYAEHLGNFQSR--NETQDLLYWQSFVDRFYSPVGVLRQGVWNNT---IGSKQFEIGTPALARYYLTQFTSGISQIQMVVEGARER-ESHNGGHYVEAPKCSFIYWF--KNECQLFTNGTLRAHFDM-----HNKLEMLDVNVVSHNEFIPRSLLLAIEADSQKQSPKNVTANGVPTPVMGFMEVAETISAMQMLFQFSQANPQLSPPDALR......................................................................................................................................................................................................................................................................................................................... 223
2 -9.110PF08580.10; V5HV84_BYSSN/491-1186; Yeast cortical protein KAR9  ali follow..  9  250.................................................................................................PLRASLDFLPMRLSMFQSRAERIFPTAC-YKKLESDA------------------------VLRKELDEDRWVLVFRNAGRQARTMCESVERSIGKLQEAL----ESFEAKKIHYGPAIERV---------LSIIEKGVKDRITVNGEILRLLHEMRSR-----------------------------VDALNASIKVMDGLLDDIDFSKTQQLRDSISSIITMDSPATGSVVDTPGSSPASSVVLSNGNGRKGSSTPNVGSSSRRGSSVASTNRKRYSGIPQGAATLSAGRRSSIPRASFSGSLTSPTRSQTNPSFTPRPASRTSTAPTKTPDNRPRWNSSTNTNDLNIGHTHKTLSATTPSRNPNRNSRSNIPTPSPLSREASRSPVPPHMRSSSRAMSRLASPTPNRLYSPTPSRSILDPPP--YSKLRKQSTPNLPTGARNRQSYAGISITRSSPVEDRTKTQRPETSLGHSTASRRLSGIP.............................................. 696
3 -7.870PF15782.5; H2M7V5_ORYLA/1-1933; Gene regulated by oestrogen in breast cancer  ali follow..  10  2..............GNSY-------GQL-RSARFEEVLHNSIVFYLETEQSFVFFAGRAENDDEDDEDGSESNSPPIPYQMKPPPEGCCTADGFCQAGKDLRLSSLASDLVGVKSPSLPDN-------AVDHRFLPDEALLGFS----NCMGCGEKGF--------RYF-TEFSNHI-NLKLSTQPKKQ----------------------------------------------------------KHLKYHLYRN-----------------------------------------------------KQGILVKGAPICWRVNVINAGCGSCCSVSSSSFSLLLCCSPISFAPSATVMKRSDTGRIGAKEIGMAGPHVDQQTTDLAHTLINGNHSAPSSAQSSLNQPGRSSAPATHTNAGPPKKRHKGWSPDLSANSLQESTVKSPPASLSLSTLSVSSVVTPSAAIF-------PPLQLSVTVPDQLLHTCRLQPVILKGHGPLPQLTGNVRDILVSSLLHSCYMSSQTLPRIYQHYGPSPIQPLSTEMQIPEQVPLVEDLEQIFMRSWRESHLSEIRQFQQPQAPAVQSQQTLTPSQLP......................... 490
4 -7.470PF07220.11; D4HSK9_LEPIR/4-673; Protein of unknown function (DUF1420 topsan)  ali follow..  12  1......MKF----------GLDAAYPPLSVLYSI-DFLYILKLFESSLGKVKNTWIRWQAPLIGA----------------------------------------LSVILYPLALS------------ALTPRFLMKSAAIFLSVLGCANICFFVKN--TKNLVSISYYSNIFKSIQYHSFFNDKKIKKSFSLFKLIGFIKNKFNLINKNDVLNVFIILLMIGYGFLALCPNADSLDYHIGVAIEILNQGKMPVFSGWFHGRLAGSGEVLNALGLAIGAEQSLLQFCGLLSIYGILSFYSFAEKFSESDGVWRKIIIIAFLSSPVLVFLVSSPKPQ..................................................................................................................................................................................................................................................................................................... 286
5 -7.400PF04388.12; F7E2N6_XENTR/7-705; Hamartin protein  ali follow..  10  81LPTLTLLGHVIRRQPSWKH-------KLSQAPVLQSLL-VLITVLPMIPQSGKQHLY--------------------------------------------EFFDIFGRL--------------ATWCLKNPGRVAKICLVHL------------------HASVYALFHRLY--GMYPCNFVLRSHYSMK-----------ENLETFEEIVKPMMEHVRIHPEL-VTGSKDHELDPSR---WR---LETHDIVVECAKISLDPSEASYEEGYSP-------------------------LSNRLRQRQHDTTSSPYTEIGCNYGSNASTPFSTPRMCAHSASIHSGGIELLQDSIWSPSTICGMTTPPNSPANVLADAAHSSSRPHSKVLYTPVGGKITPLGTPATSPPPPSNSEECTPAAGASLTLTPHKKNESFDPGRSLVNRQLLSKGEKSADESPKTQKTVYLSELPDIIGDLAADHNSTEEEQETRAAICQELSQITTADPEPTVLRGGFDSPFSLRCDSQPSSQKKFPSYGVGHIPEHSAPNKLHYSAPHDSSKQAFTPIEPPNGTENAADSGKPPSNNSLPSAVDIFTPQVQRNVSCFSLPPYDHLFELALPKTAN..... 595
6 -7.270PF05518.11; CAPSD_HV19S/10-772; Totivirus coat protein  ali follow..  9  208..IVDALRLLGSNRGIHRHTDEGGIVR-CGGFAYVDGIALVTAAVVAHADPGERYNGEWFPTFFDGTTHADTMRRSGDSTEGTAAMAD----------------RNRAQLL---------ARQQLFWRPYITACFSDISVAERFQCAASHSLGADPRHLRLPSVAPYFW---IEPT---IPHDFLGSVAEEEGFASYCWRDTTRTRPAWDSIVLSGARDTTFSAYHIRMK------GARTAWFLAHWLGHPE---------GATRVRQLDPNAVLHPGPCEGNEQVRDRVEADLPLTDYLWRRGQSPFPAAGELLNLTSEWGILFRHVTFTDDGDLNPEHLPAAHEMADTTVTMTVGRPIGIAPGRSNAGDNQARRARTRASVELSAASRRARVFGRPDVGEMPTLTSAPAPIPASPAYDGNRGGEAGGVTGRGNNRSAAPGHASWSERQADGVPVNVTPHHNALRAPPFPRQQGALGGGGNVPLPPAPGAAPPPPPGPPNGPPAGPPPSDDGSSNPAAPVPTAIHAPPAAAQADRAEGQ......................................................................................... 763
7 -7.260PF08549.10; E3Q6J3_COLGM/3-717; Fungal domain of unknown function (DUF1750 topsan)  ali follow..  8  64....VYLTWQFASDGYVKSGGEQVAMHARRRFRL-----LWIVHYGPSDPPDRVPPQIQFPRNGGRPQMYNPPAQSRRIPQQMAYPPTGPQGRRGRQQAQAQAQAQQHQQALAHAEALHDDEELE-------DLFDHLTPRDISF----------ARYQQNHEWMEEIVSSPYGLS-PDLGLGLKGELASLT------IFPAQSADALTEPPQKPYIGRLEPGLA--EF---RKRVREHLDATKAEMEKMKAEHAKNLASLKASSVFVDAEKD----------------------IKNSVQEHGPEPWRIEGHYTDSEDNSGPWSQKHNKKVDEIVAQVEANLGRQIEVLHNVHRIQDGGFQEPAPEPVKEPSPVPPPASSLPPAAGADTGALGSRRPSQAGSTHSGVMVGDSDIDMGGTAAGLLDEMHTGFSANSTPLNNFPTPQTHMSALNSTAGTPANANAPSPAPVPPTIPEETETQASAGASAGAAEDVTMGNTGSTKNTPATAPDHGTGSGEWVVVPKGGTSPDPGAGAATSTGATEGDEPKAAAKIPSAAGTPVETQTPGGFSSLGDLDSAGDAMASYGASMADG..................................... 691
8 -7.170PF03326.13; BRLF1_ALHV1/105-619; Herpesvirus transcription activation factor (transactivator)  ali follow..  11  19.CATAIIRFF----------LE----RVIRH----DKWFLLIL---------------------------------------------PQELAKE-----YVLLEARGKAL---------------GRMFSGG--------------------RQNMMNAAKKVL---YSSLRDDGE-----------------------------------------ISPEVKAYMAYIF-------DIEQVFQPLFKLEQEIRKGKATLTQSLLFAPRKRCPNKTVFSQYGAR---------PEVLLEASEPQSTLAYGCPDISSLLRDSSSTQENTDEESGPCCSKTLSPGVPQPQSEYDPSPTSPPDSDTESCDSQVRPESTDSDTHAEDDDVPEAPQAASQTQPTTTQETQSCCSVYNPATTQTGFYYNQQSSDNFASRIDASATSTSYGYPGPVTNHGFSTSVFSHTVPTTATGQQQLHQNMYGGGQQTTTYGSYVGGYSDANGQSVGASTSYYTSKPATSRSSTALQWTTLFPPASSSASSSQVSDYFSGFPYFPGSSTVPQAFEPLAPSTPSLLDELLDRDSGLVSQQQAPAPPQNDQGGPPQYVPVAQEQQQSSTDPLSDEMRRI..... 502
9 -6.960PF07267.11; Q2NNY4_NPVHC/1-628; Nucleopolyhedrovirus capsid protein P87  ali follow..  10  3........................................................................................................................................................................................................EQDNSLRIVT----LAGHILTRDRAAINVIMRNP---------EQALGQKFDAIKTFVDSLKPGALLENERQINSVVIANDSIMRHRVLQIAVVTLNTIQNLLNDYETHVKKDILDETVIEGFLNNASALYNELRDNNILPFIKNAEKQAPSRTEKEKPSLEQMVQTPLPPTGEKELQQEIIASPPVIRNEQDFDKLNIRQLSDYINRNNRKLLNYTAAHESVDDVRNFAKAVWRANNAPDYTEQTPMPEQSWQSPQQTPAYTEQTPMPEQSWQSPQ-QTPAYTEQTPMPEQSWQSPQQTPAYTEQTPMPEQGWQSPQQTPNLQPMQTPNPVYEWEEKLREMFPSDLSLQSQKESSSSNGSTVGGFTRRRRRRAPPLPELSSEEEEDPPKNVNQQMYSSEEDEPDKELARKRRREEDK........... 419
10 -6.820PF15361.6; H2L6I9_ORYLA/15-166; Resistance to inhibitors of cholinesterase homologue 3  ali follow..  16  3LCVALLLPKILLSRGRKDHSPETSAGQIIPVYGFGILLYILYILFKITSKGSSKPPESKFHPIRSENMKRKIT--------------------------DFELAQLQEKLRV..................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 142
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 1 0 5   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Godzik A. cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences. Bioinformatics. 2006 May 26;