current user: public
If you have questions about the server, please let us know.

Query: [MU] KOG2516 Protein involved in dolichol pathway for N-glycosylation (mannosyltransferase family), from COG1018

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
    .   10    .   20    .   30    .   40    .   50    .   60    .   70    .   80    .   90    .  100    .  110    .  120    .  130    .  140    .  150    .  160    .  170    .  180    .  190    .  200    .  210    .  220    .  230    .  240    .  250    .  260    .  270    .  280    .  290    .  300    .  310    .  320    .  330    .  340    .  350    .  360    .  370    .  380    .  390    .  400    .  410    .  420    .  430    .  440    .  450    .  460    .  470    .  480    .  490    .  500    .  510    .  520    .  530    .  540    .  550
# Score Template Links and tools%idFirst MRWSVLDTVLLTVISFHLIQAPFTKVEESFNIQAIHDILTYSVFDISQYDHLKFPGVVPRTFVGAVIIAMLSRPYLYLSSLIQTSRPTSIDVQLVVRGIVGLTNGLSFIYLKNCLQDMFDEITEKKKEENEDKDIYIYDSAGTWFLLFLIGSFHLMFYSTRTLPNFVMTLPLTNVALGWVLLGRYNAAIFLSALVAIVFRLEVSALSAGIALFSVIFKKISLFDAIKFGIFGLGLGSAISITVDSYFWQEWCLPEVDGFLFNVVAGYASKWGVEPVTAYFTHYLRMMFMPPTVLLLNYFGYKLAPAKLKIVSLASLFHIIVLSFQPHKEWRFIIYAVPSIMLLGATGAAHLWENMKVKKITNVLCLAILPLSIMTSFFISMAFLYISRMNYPGGEALTSFNDMIVEKNITNATVHISIPPCMTGVTLFGELNYGVYGINYDKTENTTLLQEMWPSFDFLITHEPTASQLPFENKTTNHWELVNTTKMFTGFDPTYIKNFVFQERVNVLSLLKQIIFDKTPTVFLKELTANSIVKSDVFFTYKRIKQDEKTDLast
1 -82.200PF03901.17; F4K887_ARATH/41-451; Alg9-like mannosyltransferase family  ali follow..  14  1........IFLFCLAFRVVNALLIQTDEHWQLEVAHRTIFGYGYMTWEWKR----------------------------GIRSYLHPMLFAFLYKLLQVTGLDTPYIMIKAPRLMQSIFSAIGDLYLYKLSDAL--YGGNVATWSLFCQMANWFIFFCLNRTFSNCLETVLTIMGLYYWPCIRDSSIWGLVIAALACAIRPTSAVIWLYVGMLELFLTPNKVKFIILEVIPIGSLVLGFTCLLDRLMYGSWVIVPLNFLKFNFLSSGGDYYGTHPWHWYFTQGFLVMLFTFTPFSIAGII----KSKNQKLSALILWVLAIYSILGHKEFRFVLPVLPIALIFSGYAFAQMEVSGSSSSSSVTKKKVPRQNHTKWSPKLRLSVYFLLATNIPMALYMSLFHLMPCHSTPYYSTLH........................................................................................................................................ 411
2 -14.500PF09852.9; Q10XG3_TRIEI/32-516; Predicted membrane protein (DUF2079 topsan)  ali follow..  7  60...........................................................................................ALLLWLPIYVLFPYPITLTVLQVTLISVSGLVLYIL-----ARQHLQPQLSAMMSISFYGANAVIGPTLANF-HDICQIPLFVFSLLLAMEKRWWSLFWILAVLTLAVREDSGVVLFGVGFYLILSKRYPKIGLAICTLSFSYMIALTNLIMPVFYTEGDQASTLEIIW-GMM--------SNPWRLIIFTPFFGTLKYLLGQWLPLAFVPAVAPAAWMIAGFPLLKLFSAKGLSVLSIRYAMTVVPGLFYGAILWWGKRESEVKNSPVPSPKFLRFWVVCICLSLFFTFTSNPNRTFYFLVPDSVKPWVYIPANEQWQHVSQKIPDDASVAATTYIIPHLSSRRAILRFPRMQFRNDAKKIEKVQYIIVDLETIVPRIEELYNSGEYGITDFGDGV............................................................... 483
3 -12.200PF02516.14; STT3_SCHPO/23-509; Oligosaccharyl transferase STT3 subunit  ali follow..  8  2LKVLILICIAVASVSSRLF-SIIHEFDPWFNFRASKILVEQGFYNFLNFDERSWYPLGRVAGGTLYPGLMVTSGIIFKVLHLLRINVNIRDVCVLLAPAFSGITAIATYYLARELKSDACGLLAAAFMGIATSRSVAGEAIAITLLMSTFALWIKAVKSGSSFWGACTGLLYFYMVTAWGGYVFITNMIPLHVFVLLLMG-AYTTYYVIGTLASMQVPFVGFQPVSTSEHMSALGVFGLLQLFAFYNYVKGLVSSKQFIIASVSEHQPPTWSS-----LFFD-----LQFLIWLLPVGVYLCFKELRNEHVFIIIYSVLGTYFCG--VMVRLVLTLTPCVCIAAAVAISTLLDSKNIGIYSLLSRVLVISSTAYFLIMFVYHSSWVTSNAYS............................................................................................................................................................... 487
4 -11.300PF15971.5; D2RW44_HALTV/57-219; DolP-mannose mannosyltransferase  ali follow..  7  12.....................................................................................NPPVPFAITAALAVLSGGNMYVLHGLSVILTLLVAAANILLVGWVAFLVTGEDAAAVAAGLTMLVVPELFLLPLAGVWAQFYALFFGVLSL--ALALRDRPFLAGVAAALSAGSWQSGIAFAPLVVGMTYQRTGGKDVLRAIAGGGVVTGVVVL........................................................................................................................................................................................................................................................................................................................ 163
5 -10.900PF09913.9; Q83H24_TROWT/46-427; Predicted membrane protein (DUF2142 topsan)  ali follow..  9  106...........................................................................................LYYSAMGLLASDDVRASVWGMRLINAFIFTALSLLLYLALPQPRRAALLITWSLSLVPAA----MFFIPSSNPSSWAFSTFFAMLSFFETRGRRKICLGIIAVFSVLLRSDAAIYALLAIVISGILQVRDFKNPWAQFALPVALGIMSIATFFMYPLNVAATGLPA--SFLPSVFTPQFLG------WLDVPLYPPAYVFVAIAALIIVGFALGVGGVRKLFAVLLTLAALIIAP--QPRYLAPLAII.................................................................................................................................................................................................................... 382
6 -10.700PF11893.8; J7TLV1_MORMO/5-252; Domain of unknown function (DUF3413 topsan)  ali follow..  8  10....................................................................................................................................................QMISWGHWFTLFNIL-----LSLALSSRYLFISDWPDTLIGRIYAITSWLGHFSFLAFALYLLIVFPLTFVVMSQRLLRFLSAALGTAGLTLLLFDIGIYEQFRL--LNPVVWDLVVNPEQG--RRWQFIFIAIPVIFLIEMLFGTWSWQKLRSLNRQKFGKPVAVVFITAFITSHIMYRPVTMQRYNLPVSYPMTARKF........................................................................................................................................................................................................... 212
7 -10.300PF13231.6; Q2YBZ2_NITMU/191-351; Dolichyl-phosphate-mannose-protein mannosyltransferase  ali follow..  10  22.............................................................................................FGVRVGAFLCGLITMGYLFALTRNLY------------------DSATGIRAVLLLAILPFFFATGALMTTDAPLVAAWAATLYYLEQRERAWLGVGIAFGLGILSKYTLGLVGIAALVFVIIDPVAR--RWLRHPYPYLAVLLALLLFSPVIIW............................................................................................................................................................................................................................................................................................................... 161
8 -9.410PF13214.6; Q81V06_BACAN/1-77; Protein of unknown function (DUF4022 topsan)  ali follow..  23  6.......................................................................................................................................................................................................................IMSIITLALLLLAEILVAIILIGVSIEICSYGWKKSNGIKYSCLLLSLLLGTASILGAAPAYFFI............................................................................................................................................................................................................................................................................... 72
9 -9.360PF04602.12; W5T763_9NOCA/222-694; Mycobacterial cell wall arabinan synthesis protein  ali follow..  10  45.KPTWADGAILGTLLVWHFVGANTS-DDGYILTMVRVAPHAGY--LANYFRWYGVPEAPFGWY-----------------------------YDVIQIFAQISTASPWVRIPALLCGMLCWMVISREVVPRLGRGVRNSKVALWTGGLVFLAFWLPYDNGRSEPIVALGALLTWVSIERAIATRRAAVAILVAAFTLAAAPTGLMCVAALLLVRIVVQRKR-SGFVSSLPLLAPIAAAGFLVLTVVYSDQTFAGIQEANRVRRLTGPNLAWYEDYLRYYVARRFAFIVMILCLITTALVLLRRKRGPTWRLIGVVCGTIFFMMFNPTKWTHHFGAYAGIAGALAAVTAVAVSATALRSRKNRSIFLAALLFALALSFSGTNGYWYVSSYGVP............................................................................................................................................................... 439
10 -9.250PF10131.9; R5JZI7_9CLOT/75-690; 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein  ali follow..  10  7...........................................................................................LSYYIMAGLMFLTSGDLLLAYRLI--AFVIFVVGGLPWILWGIHENRRVLGTFFGVLWFFMPEHIRFTAGNLPQMVTTMYVIWFLWLYVRKKNNRAAVGLFVCMTLMSFTHLMVTAIMGVSAFLYLLIDQIWNKDTRRKIFALIYMICGILTAGIWV----IPSLKGGLVTSESGDGSVM-LNPFKRLSAGNDSFYFGLAAVLIAIAGILLARGGKKAGFVFLLIMLACILVKLPFSQLFWMTRFAPMVYGFFFSACLEWVRLKKKYCVLLAALLCVDSISCM................................................................................................................................................................................. 304
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 3 4 1   jobs submitted since Jan 1, 2011
Comments and questions to: webmaster
Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Robinson-Rechavi M, Godzik A. Structural Genomics of Thermotoga maritima Proteins Shows that Contact Order Is a Major Determinant of Protein Thermostability. Structure (Camb). 2005 Jun;13(6):857-60.