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Query: [R] COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid), from COG1018

Results of FFAS03 search in SCOP207
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MLMITSFANPRVAQAFVDYMATQGVILTIQQHNQSDIWLADESQAERVRGELARFIENPGDPRYLAASWQSGQTNSGLRYRRFPFLATLRERAGPVTWIVMLACVLVYIAMSLIGDQTVMVWLAWPFDPVLKFEVWRYFTHIFMHFSLMHILFNLLWWWYLGGAVEKRLGSGKLIVITVISALLSGYVQQKFSGPWFGGLSGVVYALMGYVWLRGERDPQSGIYLQRGLIIFALLWIVAGWFDWFGMSMANGAHIAGLIVGLAMAFVDTLNARKRTLast
1 -80.500d2xova_ f.51.1.1 (A:) GlpG {Escherichia coli [TaxId: 562]}  ali model 3D-neighbors follow..  89  1..........................................................................................ERAGPVTWVMMIACVVVFIAMQILGDQEVMLWLAWPFDPTLKFEFWRYFTHALMHFSLMHILFNLLWWWYLGGAVEKRLGSGKLIVITLISALLSGYVQQKFSGPWFGGLSGVVYALMGYVWLRGERDPQSGIYLQRGLIIFALIWIVAGWFDLFGMSMANGAHIAGLAVGLAMAFVDSLN..... 181
2 -78.800d2nr9a1 f.51.1.1 (A:4-192) GlpG homolog HI0618 {Haemophilus influenzae [TaxId: 727]}  ali model 3D-neighbors follow..  37  3..........................................................................................AQQGKITLILTALCVLIYIAQQLGFEDDIMYLMHYPAYEEQDSEVWRYISHTLVHLSNLHILFNLSWFFIFGGMIERTFGSVKLLMLYVVASAITGYVQNYVSGPAFFGLSGVVYAVLGYVFIRDKLNHHLFDLPEGFFTMLLVGIALGFISPLFGVEMGNAAHISGLIVGLIWGFIDSKLRKNS. 187
3 -10.100d2hfva1 d.58.5.5 (A:23-97) Hypothetical protein RPA1041 {Rhodopseudomonas palustris [TaxId: 1076]}  ali model 3D-neighbors follow..  11  1LRELLRTNDAVLLSAVGALLDGADIGHLVLDQNMSILVLVHEDDLAGARRLLTDAGLAHELRS..................................................................................................................................................................................................................... 73
4 -6.860d4hyja_ f.13.1.0 (A:) automated matches {Exiguobacterium sibiricum [TaxId: 332410]}  ali model 3D-neighbors follow..  10  44...............................................................................................VAALVTFVAAIHYYFMKDAVGTSGLLSEIDGFPTEIRYIDWLVTTPLLL------VKFPLLLGLKGRLGRPLLTKLVIADVIMIVGGYIGESSINIAGGFTQLGLWSYLIGCFAWIYIIENKPAPIRDALLKMRLFILIGWAIYPIGGVEIQLVRELIYFADLTNKVGFGLIAFFAVKTMS 238
5 -6.630d2wdqc_ f.21.2.2 (C:) Succinate dehydrogenase subunit SdhC {Escherichia coli [TaxId: 562]}  ali model 3D-neighbors follow..  16  19......................................................................................ASILHRVSGVITFVAVGILLWLLGTSLSSPEGFEQASAIMGSFFVKFIMWGILTALAYHVGIRHMMMD------FGYLEETFEAGKRSAKISFVITVVLSLLAGVL.................................................................................... 120
6 -6.450d5jsia_ f.13.1.0 (A:) automated matches {Candidatus actinomarina [TaxId: 1389454]}  ali model 3D-neighbors follow..  9  39...............................................................................................ISALVCGIAWYHYQKMGASWESGSYDTGLRYVD-------WVLTVPL--------MFVEVLAVTRKGAAYNEAVRNWGIATVMIGAGYYGETSYWTGFVIAMATYVWLMRNLQAEGEGLKGDQAVAFENIKNLILVGWIIYPLGYIAPVVGDFDAIRE-IADIINKVGLGVLVLQMARVQS 214
7 -6.430d3t6el_ f.26.1.1 (L:) automated matches {Blastochloris viridis [TaxId: 1079]}  ali model 3D-neighbors follow..  19  78...............................................................................................................................APLLEGGFWQAIT--------VCALGAFISWMLREVEISRKLGIGWHVPLAFCVPIFMFCVLQVFRPLLLGSWGAFPYGILSHLWVNNFGYQYLNWHYNP--------GHMSSVSFLFVNAMALGLH-GGLILSVA............. 198
8 -6.420d3wu2d_ f.26.1.1 (D:) automated matches {Thermosynechococcus vulcanus [TaxId: 32053]}  ali model 3D-neighbors follow..  8  94.................................................................................................................................CQLGGLWTFIA--------LHGAFGLIGFMLRQFEIARLVGVRPYNAIAFSAPIAVFVSVFLIYPLGQSSWFAPSFGVAAIFRFLLFFQGFHNWTLNP--------FHMMGVAGVLGGALLCAIH-GATVENTLF............ 212
9 -6.390d5hnva1 d.144.1.0 (A:11-293) automated matches {Serratia sp. [TaxId: 1327989]}  ali model 3D-neighbors follow..  12  1..........SNSLPSGYRFNEFEIQEAIGEGGFGIVYRAYDHQLERTIAIKEYMKRNDDLSIGLRGERFGKTFQAGLNSFIQEARLLARFSHPGLLHVFWEENGTAYMGTQFYSGTTLKNLQAQQPEKIDEAWIRRLLPPLFIH-GYLH---NIQILLDFGSARKEIGNLSDETEIVLKPGFAP-IEQYTENSDGEQGPWTDIYALGAVLH................................................................ 224
10 -6.290d2fbwc_ f.21.2.2 (C:) automated matches {Chicken (Gallus gallus) [TaxId: 9031]}  ali model 3D-neighbors follow..  10  48...............................................................................................LSLGVSLFSVAALLLPEQFPHYVAVVKSLSLSPALIYSAKFALVFPLSYHTGIRHLVWD------MGKGFKLSQVEQSGVVVLILTLLSSAGIAAI..................................................................................... 139
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 3 4 1   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Jaroszewski L, Slabinski L, Wooley J, Deacon AM, Lesley SA, Wilson IA, Godzik A. Genome pool strategy for structural coverage of protein families. Structure. 2008 Nov 12;16(11):1659-67.