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Query: [S] COG4625 Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain, from COG1018

Results of FFAS03 search in SCOP207
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MIRGIARRPRCAVEGDWMSAGFCHVSEGKACPTAEMRGVALGRFLICGATGLSFLTLSLAAVSDAVAETLLWTGPDGAEWFTDAAWGPSHRVPNAGDDAMINTYGPVITIGTNAEVHQLSIGNAPGDGTLVVQGGLQTNSVILGATGGSSGTASFIGANWANDGDVSVGGNGTGSLLLLHGTTASSENIYVGESGTGSGSLKLDNSSTLTVADTVFAGYNSWSSSAAGGSGNVEVLGASSLYSANGVLANDPDTVGTALVSGGGSSWNMSSDLVVGEAGVGTLTITGGGMVISQTTTVIADLNSADGSSVTVSRLGSSLQSDSLVVGNGGAAKLVVEAAATVTSGEAIIGRHSASEATVTGDGSKWTTGDLQVGGDTSDPGGLAGNGTLNVTAGGSVDSTVAHLGVVAGATGSAIVDGKGSVWTVDRNSLEVGVSGAGSLAVTGGGLVDAANIIIGTNTGGNGSVRVSGADSTVKSRSDLNVGLYGNGSMTVEAGGAVKSRDGYVATYGGSTSAVTVTGDGSSWAMTGTFFVGYASGATGNVTVSNGGAIRATGVTLGDLAGASGTMTITGAGSKVTAYVDNGTVNSGSVDVGFQGSGSLSVVNGGSLDAYNLYVGNALGSSGAVLVSGVGSHVSVDGLMVVGNAGNGSVEITGGASLAAPTILIATEAGSTGVLSIGAGSGQTARSAGAVEARAIAFGAGNGSIVFNHSETGYTLSADISGAGRVVAEAGVTTLSGNNSYSGGTTISAGMLKGTAKSFGSGGIVNNAELVVDGGGTLSNAISGTGSFEKTGDGNLLLTGNSTYSGATAVSAGKLSVNGSLASAVSVGSGATVGGTGTIGGLTVNSGGTLAPGNSIGTLTSTGNATFASGSTYAVEIDADGSSDRLAVTGTITIANDVSLIVTPLGAHSAYSLGTRYTILTATGGVTGTFSSVDESFAYLTAKVAQSGDDATTYLSFLRTSPDSGLLAAATSTANARAAANAVEALGQTSPLYEAALFLQQGETQGAFSQLAGEIHPSLAMALINRSGQSRDVILNRLRSAFEGVDARPILPVAYAEGGQNPFAVDDGALSFWSSGFRSRGRIDSDGNGSSVDMNGGGILFGLDGELSDSWRAGVAAGYGHDGIKQTALAASADVDSYYLAAYAGTQIGPASLRLGAIHAFQDAETRRSISFSTLQESLSASYGGSTSQVFAEAAWRFDFDLTHIEPYANIAYVNTRTDGFQEKGAIAAVSSGSTRYDQLYTTFGARISRDIALEGMLGRAMFDLAWRHNYGDTAMGSSLFYEGGGVFSVASTSSPRDAAILNLGLSYDLTPSATLTFRYGAVFGAGVLDQSAAAELGVRFLast
1 -42.900d1uynx_ f.4.5.1 (X:) Translocator domain of NalP {Neisseria meningitidis [TaxId: 487]}  ali model 3D-neighbors follow..  15  1...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................AATVYADSTAAHADMQGRRLKAVSDGLDHN---------------------------GTGLRVIAQTQQDGGTWEQGGVEGKMRGSTQTVGIAAKTGENTTAAATLGMGRSTWS----ENSANAKTDSISLFAGIRHDIGYLKGLFSYGRYKNSISRST---GADEHAEGSVNGTLMQLGALGGVNVPFATGDLTVEGGLRYDLLKQDAFAEKGSALGWSGNSLTEGTLVGLAGLKLSQPLSDK---AVLFATAGVERDLNGRDYTVTGGFTGAATGKTGARNMPHTRLVAGLGADVEFGNGWNGLARYSYAGSKQYGNHSGRVGVGYRF 299
2 -8.270d1p4ta_ f.4.1.1 (A:) Outer membrane protein NspA {Neisseria meningitidis [TaxId: 487]}  ali model 3D-neighbors follow..  12  1.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................EGASGFYVQADAAHAKAS------SSLGSAKGFSPRISAGYRINDLRFAVDYTRYKNYKAPSTDFKLYSIGASAIYDFDTQS----------------PVKPYLG--------------ARLSLNRASVDLGGSDSFS------------------QTSIGLG---------------------------------VLTGVSYAVTPNVDLDAGYKVNTVKNVRSGELSAGVRVKF 155
3 -7.830d4c2ma_ e.29.1.2 (A:) RNA polymerase I subunit A190 {Baker`s yeast (Saccharomyces cerevisiae) [TaxId: 4932]}  ali model 3D-neighbors follow..  11  464................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................EGLFRKHMMGKVNYAARSVISPDPNIETNEIGVPPVFAVKLTYPEPVTAYNIAELRQAVING-GATQIQNEDGSLVSLIGMSVEQRKALANQLLTPSSNVSTHTLNKKVYNRDVVLMNRQPTLHKASMMGHKVRVLPNEKTLRLHYANTGA-------NADFDGDEMNMHFPQNENARAEAL--NLANTDSQYLTPT------SGSPVRGLI------------DHISAGVWLTSKDSFFTREQY-QQYIYGCIRPEDGHTTRSKIVTLPPT-----------KPYPLWTQIITTWGKGSLENEV-----KDGALLCG----ILDKSQYGASKGIVHSLHEVYGPEVAAKVLSVLGRLFTN-TATAFTCGMDDLRLTAEGNKWRTDILKTSVDILDAVTSSKVNAITSQV---VPDGTMKKFPCNSMQAM-------ALSGA----KGSNVNVSQIMCLLG-KTLPSFKPYETDAMAGGYVKGRFYSG-IKPQEYYCMAGREGLIDTAVKTSRSGYLVHVSYDNSIADGTLVQFMY-GGDAIDITKESHMTQFEF.. 1068
4 -7.010d3qraa_ f.4.1.0 (A:) automated matches {Yersinia pestis [TaxId: 632]}  ali model 3D-neighbors follow..  11  1..................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................MEGESSISI--GYAQSRVKEDGYKLDKNPRGFNL----------------------------------------------------KYRYEFN-NDWGVI-------------SFAQTRRGFE-VDGFKLIDGDFKYYSVTAGPVFRINEY-VSLYGLLGAGHGKAKFSSIFGQSESRSKTSLAYG-----------AGLQFNPHPNFVIDASYEYSKLDDVKVGTWMLGAGYRF 157
5 -6.670d1w7ja2 c.37.1.9 (A:63-792) Myosin S1, motor domain {Chicken (Gallus gallus), Va isoform [TaxId: 9031]}  ali model 3D-neighbors follow..  10  39...........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................TYCGIVLVAINPYEQLPIYGEDIINAYSGQNMGDMD---IFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFA-TVSGSASEANVEEKVLASNPIMESIGNAKTTRNDNSSR------------FGKYIEIGFDKR----YRIIG---ANMRTYLLEKSRVVFQAEEERNYHIF--------QLCASAALPEFKTLRLGNANYFHYTKQGGSPVIDGIDDAKEMVNTRQACLLGISDSYQMG--LAGILHLGNVEFASRDSDSCAIPPKHDPLTIFCDLMGVDYEEMAHWLCHRKLATATETYIKPISLHAINARDALAKHIYANLNWIVDHVNKALHSFIGVGFETFEINSFEQ-----CINYANEKLQQQFNMHVFKLEQE---------MKEQIPWTLDFYDNQPCINLIEAKMGVLDLLDMPKGSDDTWAQKLYNTHLNKCALFE-HFADKVEYQCEG........... 501
6 -6.370d1xkwa_ f.4.3.0 (A:) automated matches {Pseudomonas aeruginosa [TaxId: 287]}  ali model 3D-neighbors follow..  14  1..............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ESTSATQPPGVTTLGKVPLK-ELPQSASVIDHERLEQQNSLDEAMQQATGVTVQGFKVDSFELDGEILRGSNGLLHGTGNPAATVNLVRKRPQREFAASTTLSAGRWDRYRAEVDVGG---LSASGNVRGRAVAAYEDRDYFYDVADQGTRLLYGVTEFDLSPDTLLTVGAQYQHIDSITNMAGVPMAKDGSNLGLSRDTYLDVD--DRFKWDTYRAFGSLEQQLGGGWKGKVSAEYQEADSRLRYAGSFGAIDPQTGDGGQLMG-----------------AAYKFKSIQRSLDANLNGLLGGVTAQGETRQDTARFLNLPNTPVNVGQYTSPGTTTTTQKGLYALGRIEPLTLVVGGRESWWDQDTPATTPYGGLIWDFARDWSVSYAEVYQPQADRQTWNSEPLSPVEGKTY---------ETG----IKGEDGRLNLSLAAFRIDSGGKVRSQGFELEGTGYLYWSYTYTSTTPRSNYDLPWQRRWSVGGVSMRQGGALVNMRLGYKIDEHWTAAVNYYQSLSNPNEPRSFNVSLRGAF 665
7 -6.350d1twfb_ e.29.1.1 (B:) RBP2 {Baker`s yeast (Saccharomyces cerevisiae) [TaxId: 4932]}  ali model 3D-neighbors follow..  11  676...........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................IDAEEEESILIAMQPEDLEPAEANEENDLDVDPAKRIRVSHHATTFTHCEIHPSMILGVAASIIPFPDHNQSPRNTYQSAMGKQAMGVFLTNYNVRMDTMANILYYPQKPLGTTRAMEYLKFRELPAGQNAIVEDSMIMNQSSIDRFRSLFFRSYMDQEKKYGMSITETFEKPQRTNTLRMKHGTY---DKLDDD-----------GLIPGVRVSGED---IGKTTPISPDEEELGQRTAYHSKRDASTPLRSTENGIVDQVLVGLKFVKVRVRTTKIPQIG---DKFASRHGQKGT--FTAEG-RMTVAHL-IECLLSKV--LLREHGYQSRGFEVMYNGHTGKKLMAQIFFGARARGPMQLTRQPVEGRSRDGGLR-FGEMERDCMIAH--GAASFLK-LMEASDAFRVHIGLMTVIAKLYQIHIPYAAKL-QELMAMNITPRLYTD. 1202
8 -6.060d1qvia2 c.37.1.9 (A:6-28,A:77-837) Myosin S1, motor domain {Bay scallop (Aequipecten irradians) [TaxId: 31199]}  ali model 3D-neighbors follow..  12  62...........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................TYSGLFCIAVNPYRRLPIYTDSVIAKYRGKRKTEIP---LFSVADNAYQNMVTDRENQSCLITGESGAGKTENTKKVIMYLA------------KVACAVKKKDEEASDKKEGSLEDQIIQAVLEAYGNAKTTRNNNSSRFGKFIRIHFGP-TGKI-ADIETYLLEKSRVTYQQSAERNYHIF--------QICSNAIPELNDVMLVTPDSGLYSFINQGCLTVDNIDDVEEFKLCDEAFILGFTKEEKQS--TASILHMGEMKFKQRPREEQAESDGTAEAEKVAFLCGINAGDLLKALLKPKVKVGTEMVTKGQNNQVVNSVGALAKSLYDRMNWLVRRVNKTLDTYIGVGFEIFDFNSFEQ-----CINYTNERLQQFFN------HHMFILEQEEYKKEG-IAWEFIFGDLQMCIDLIEKPMGILSI--FPKADDKSFQDKLYQNHMGKNAHFELHYAGNVPYSITG........... 541
9 -6.020d1qjpa_ f.4.1.1 (A:) Outer membrane protein A (OMPA) transmembrane domain {Escherichia coli [TaxId: 562]}  ali model 3D-neighbors follow..  12  5....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................NTWYTGAKLGWSQYHDTFINNNGPTHENKLGAGAFGGYQVN---------------------------------------PYVGEMGYD----------------------------GRMPYKGSVENGAYKAQGVQLTAKLGYPITD-DLDIYTRLGGMVWRADTYSNVYGKNHDTGVSPVFA-----------GGVEYAITPEIATRLEYQHTIGTRPDNGMLSLGVSYRF 170
10 -5.840d3efma_ f.4.3.0 (A:) automated matches {Bordetella pertussis [TaxId: 520]}  ali model 3D-neighbors follow..  11  5............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................LTEGTNAYTTEAMSTATGLTLS-ETPQSVSVVTRQQIEDQGDTGAILATAPGISVTGFTIDNFQFDGEIVRGATGLMTGSGNPSAAVNFVRKRPLREFAATFNASVGSWDYVRGDADISV---ITEDGRIRSRLVAAYSQGDSYVHFLDTRRRTFYGVVSADLTPDTVLTTSVEYQHNHSNGFGSGFPLFYSDGSRTDFNRSVANNAPWARQDTEATTYFVDLTHRFTNDWKLRAAYSHTDGRYLMKHVYRGGYPDRHTGIIAAPPAF----------------SNYDGNLDRDDIHFSLSAVALGWMIDNHSDIQRYAMVGPAPAIGSFDTLSPADDVRTKQTGAYLVGRFEPLHLIVGDRWSDWKTKQNQFTPYAGLTYDINDTYTASYTEIFQPQN-ARDTSGGILPPIKSKSY---------ELG----LKAAEGRLNTSAALFQTRAASGAKVEGIDLEASGQIDWNYTHFTTKDATTYRLPGAHRLTVGGVEVEQDSALVSLMARFDFNKKLSATLNYYDQIGFYSAPRNVMLNLRAQY 687
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Godzik A. cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences. Bioinformatics. 2006 May 26;