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Query: [S] COG5427 Uncharacterized membrane protein, from COG1018

Results of FFAS03 search in SCOP207
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MEFGVVARWWVFFGVLLVAGLPVASRLLPDAPDRGASVAMPLSLVVVTLATLWVGQVAYGQLVVGGVFVAVLAAAAWLARGGVEIPRKPLLEVVGVFTVAFVFLIVVRAWADGVQPAGGEQFLDFGLLQALDRAGQLPPRDMWFAGERVVYYYGGQLMASIGAHLTDTAPRFAYEPALAGVYAMGCTAAYGLASTIAAGNGGESRPVGVPTAIGGAGVALAVVVLATGVNWLVVAVPAAAAAVVVTRPRRVRAGVLGAFAFGFASNLGPVIRLLAARVDVVRAAVVAAGINADRRPAITPEAFDMWHASRFMETGLNEFPLFAYLNGDLHAHMVSVPVLFVAVAVGVAYYRTPARQRRRRWALLWGGFPVAGAAILTVNTWSLPTVFGVAALAVALADPAPATLLPTGVQRWTRRESAVGQSVQRVLLAVGVAAVGGVLAVVIAWPFVQNVLLAGASNQHLAVLPVPSQAGALVFVHGLFLAAFGAYFVSRVATSVAGWVVAAAAAGAAVAVAVAVGPVVGGVGITAVVLVGPVLGAAWWLRRRNAAGVECVLVAAGAGLVVLVEYVYLADAASYERFNTVFKVYAQVWALWSVAGGVALAGVSERRASTGGLGAVFVVGLVVAASVYGGLAVTTHAANADDASLDALEYAGNAHPGEAAAARWLGDRRRGTRIVAAPGVDPYTWQNPAASLSGVPTVAGWAHAANYHSQAAWEQRVDDIGVVYETTDAASRAAILEKYDVTYVWVGPVERARYEIPDLSADPGIEPVHRTPAVTIYRVTDDELVAPRSGPITVTTTPQAATATAPGAQTARSPARFVTVTSSASTAVTSSQWGTKLRFSLast
1 -6.120d1rwia1 b.68.9.1 (A:11-264) Serine/threonine-protein kinase PknD {Mycobacterium tuberculosis [TaxId: 1773]}  ali model 3D-neighbors follow..  10  12......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................FRLSPSGVAVDSAGNVYVTSEGMYGRVVKLATGSTGTTVLPFNGLYQPQGLAVDGAGTVYVTDFNNRVVTLAAGSNNQTVLPFDGLNYPEGLAVDTQGAVYRGNNRVVKLAAGSKTQTVLPFTGLNDPDGVA--VDNSGNVYVTDTDNNRVVKLEAESNNQVVLPFTDITAPWGIAVDEAGTV--VTEHNTNQVVKLLAGSTTSTVL------------------PFTGLNTPLAVAVDSDRTVYVADRGNDRVVKLT 251
2 -6.000d2wq7a1 c.28.1.0 (A:2-215) automated matches {Fruit fly (Drosophila melanogaster) [TaxId: 7227]}  ali model 3D-neighbors follow..  7  1..............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................DSQRSTLVHWFRKRLHDNPALSHIFTAANAAPGRYFVRPDWMQVGANRWRFLQQTLEDLDNQLRKLNSVVRGKPAEVFPRIFKSWRVEMLTF----ETDIEPYSVTRDAAVQKLAKAEGVRVETHCSHTIYNPELVIAKNLGKAPITYQKFLGIVEQLKVPKVLGVPEK................. 179
3 -5.900d1ub1a_ d.10.1.3 (A:) Methyl-CpG-binding protein 2, MECP2 {Chicken (Gallus gallus) [TaxId: 9031]}  ali model 3D-neighbors follow..  12  1............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................APAVPEASASPKQRRSIIRDRGPMYDDPTL-GWTRKLKQRKS---GRSAGKYDVYLINPQ---GKAFRSKVELAYF-----EKVGDTSLDPNDFDFTVTGRGSPSRREQRPPKKAKSPKSPGSGRGRGRPKGSG...................................... 125
4 -5.880d3pt9a1 b.34.12.1 (A:731-911) BAH domains from DNA methyltransferase 1 (DNMT1) {Mouse (Mus musculus) [TaxId: 10090]}  ali model 3D-neighbors follow..  6  2...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................DRISWLGQPMKIEE--VSIDEEMLEVGDCVSVIPDDSSKPLY--HWFCAGTDTVLGATSDPLELFLVGECENLSYIHSKVKVIYK--GTDPETTLPGAEDGKTYFFQLWYNQEYARFESPPKTQPTEDNKHKFCLS............................................. 169
5 -5.840d1u3da2 c.28.1.1 (A:13-197) Cryptochrome {Thale cress (Arabidopsis thaliana) [TaxId: 3702]}  ali model 3D-neighbors follow..  10  2....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................SIVWFRRRVEDNPALAAAVRAG----PVIALFVWAPEEEGWLKNSLAQLDSSLRSLGTCLITKRSTDSVASLLDVVKSTGASQIFFN----HLYDPLSLVRDHRAKDVLTAQGIAVRSFNADLLYEPWEVTDELGRPFSMFASMPYDPESPLLPPKKIISGDVSKCVADPLVF....... 185
6 -5.820d1zroa2 a.264.1.1 (A:283-601) Erythrocyte binding antigen region II {Malaria parasite (Plasmodium falciparum) [TaxId: 5833]}  ali model 3D-neighbors follow..  5  70......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................LCLGNIDRIYDKNL--LMIKEHILAIAIYESRILKRKYKNKDDKEVCKIINKTFADIRDIIGGTDYWNDLSNRKLVGKINTNYVHRNKQNDKLFRDEWWKVI---KKDVWNVISWVFKDKTKEDDIENIPQFFRWFSEWGDDYCQDKTKMIETLKV--KPCEDDNCKRKCNSYK-EWI---SKKKEEYNKQAKQYQEYQKGNNYKMYSEFKSIKPEVYLKKYSEKCSNLNFEDEFKEELHSD................................ 308
7 -5.800d4ikva_ f.38.1.3 (A:) Microbial PepT or POT {Geobacillus kaustophilus [TaxId: 1462]}  ali model 3D-neighbors follow..  11  30TEFWERFSYYGMRAIL-------VYYMYYEVSKGGLGLDEHLALAIMSYMSGIIGGWRVFGTSRAVFYGGLLIMAGHIALAIPGG-------VAALFVSMALIVLGTGLLKPNV---------------SSIVGDMYKPGDD--RDAGFSIFYMGAFLAPLVVGTAGMKYNFHLGFGLAAVGMFLGLVVFVATRKKNLGLAGTYVPNPLTPAEKKKAAAIMAVGAVVIAVLLAILIPNGWFTVETFISLVGILGIIIPIIYFVVMYRSPKTTAEERSRVIAYIPLFVASAMFWAIQEQGSTILANY-ADKRTQLDVAGIHLSPAWFQSLN------PLFIIILAPVFAWMWVKLGKRQPTIPQKFALGLLFAGLSFIV-IWLVLSYFIVVLGELCLS........................................................................................................................................................................................................................................................................................................................................................................................................................................................... 416
8 -5.670d1np7a2 c.28.1.1 (A:1-204) Cryptochrome {Synechocystis sp. PCC 6803 [TaxId: 1148]}  ali model 3D-neighbors follow..  10  1.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................MKHVPPTVLVWFRNRLHDHEPLHRALKSGYDPRQFAQTHQGFAKTGPWRSNFLQQSVQNLAESLQKVGNVTTGLPEQVIPQIAKQINAKTIYY----HREVTQEELDVERNLVKQLTILGIEAKGYWGSTLCHPEDLPFSIQDLPDLFTK..................................... 159
9 -5.660d1owla2 c.28.1.1 (A:3-204) DNA photolyase {Synechococcus elongatus [TaxId: 32046]}  ali model 3D-neighbors follow..  9  2...................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................PILFWHRRRLSDNIGLAAARAQS---AQLIGLFCLDPQILQYLQGCLQELQQRYQQAGSRL-LLLQGDPQHLIPQLAQQLQAEAVYWN----QDIEPYGRDRDGQVAAALKTAGIRAVQLWDQLLHSPDQILSGSGNPYSVYG...................................... 148
10 -5.520d4dhla2 d.159.1.1 (A:121-431) automated matches {French bean (Phaseolus vulgaris) [TaxId: 3885]}  ali model 3D-neighbors follow..  12  39.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................VLFVGDLSYADRYPNHDNVRWDTWGTERSVAYQPWIWTAGNHEIEFAPEINETEPFKPFSYRYHVPYEASQSTSPFWYSIKSAHIIVLSSYSAYPQYTWLKKELRK------------------VKRSETPWLIVLMHSPLYNSYNHHFMEGEAMRTKFE--------AWFVKYKVDVVFAGAYERSEVSNIAYKITNGLCTPVKDQSAPVYITIGDAGNYGVIDSNMIQPQPE......................................... 258
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 3 2 2   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li Z, Ye Y, Godzik A. Flexible Structural Neighborhood--a database of protein structural similarities and alignments. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D277-80.