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Query: [O] COG5596 Mitochondrial import inner membrane translocase, subunit TIM22, from COG1018

Results of FFAS03 search in SCOP207
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MSLSGLLPPNLGGNSPNADGNLTPEEKAALQQAKIIGYMNRISESCVFKSSMAGVLGFGLGGIFGMFISSLDLQHIDPKIYEKPFREQIRIQARDMGSRSFSTAKNFGLLGLIYSGSECCIEAFRAKTDIYNAIAAGVFTGGALAVRSGPKAIVLGGAGFGLFSYGIEKYMHWGELast
1 -6.250d1miwa2 d.218.1.4 (A:1-139) tRNA CCA-adding enzyme, head domain {Bacillus stearothermophilus [TaxId: 1422]}  ali model 3D-neighbors follow..  10  10............................................GIIQQLKQHGYDAYFVGGAV------RDLLLGRPIGDVDIATSALPEDVMAIFPKTIDVGSKHGTVVVVHKGKAYEVTTFKTDGDYEDYRRPESVT-RSLEEDLKRRDFTMNAIAMDEYGTIIDPFGGREA 135
2 -6.220d1nt2a_ c.66.1.3 (A:) Fibrillarin homologue {Archaeoglobus fulgidus [TaxId: 2234]}  ali model 3D-neighbors follow..  20  16.........................................................................................................TKSKYGSHYG--EKVFDGYREWVPWRSKLAAMILKGHRLKLRGDERVLYLGAASGTTVSHLADIV..... 78
3 -6.060d1vkha1 c.69.1.32 (A:1-261) Putative serine hydrolase Ydr428c {Baker`s yeast (Saccharomyces cerevisiae) [TaxId: 4932]}  ali model 3D-neighbors follow..  10  34.........................................................YIHGGAW---------------NDPENTPNDFNQLANTIKSMDTESTVCQYSIEYRLS-AVSNITRLVKEKGLTNINMVGHSVGATFIWQILAAL....................... 123
4 -6.020d2rc5a1 b.43.4.0 (A:7-158) automated matches {Leptospira interrogans [TaxId: 173]}  ali model 3D-neighbors follow..  14  61............................................................GQSGGVIPPGEDPEKKAKGLADVGYTVRLYSIASPSYSFGMK------------DNIEFIIKRDNIYDENGNIQFKGVCSNYMCDLKPGDEVTMTG................... 145
5 -5.950d2fuka1 c.69.1.36 (A:3-220) XC6422 protein {Xanthomonas campestris [TaxId: 339]}  ali model 3D-neighbors follow..  8  50......................................................................................SMHNKVVTMAARALRELG--ITVVRFNFRSLRAVAEWVRAQRPTDTLWLAGFSFGAYVSLRAAAALEPQVLISIAPPAGRWDF...... 147
6 -5.940d1cola_ f.1.1.1 (A:) Colicin A {Escherichia coli [TaxId: 562]}  ali model 3D-neighbors follow..  14  44......................................................FQGKTIRSFDDAMASLNKITANPAMKINKADRDALVNAWKHVDAQ--DMANKLGNLSKAFKVADVVMKV----EKVREKSIEGYETGLMLEVESWVLSGIASSVALGIFSATLGAYA.... 158
7 -5.890d1ciia1 f.1.1.1 (A:451-624) Colicin Ia {Escherichia coli [TaxId: 562]}  ali model 3D-neighbors follow..  10  24..............................................LAREMAGQAKGKKIRNVEEALKTYEKYRADINKKINAKDRAAIAAALESVKLS--DISSNLNRFSRGLGYAGKFTSL----ADWITEFGKAVRTENWRPLFVKTETIIAGNAATALVALVFSILT.... 142
8 -5.710d2xova_ f.51.1.1 (A:) GlpG {Escherichia coli [TaxId: 562]}  ali model 3D-neighbors follow..  14  92........................................ALLSGYVQQKFSGPWFGGLSGVVYALMGYVWLRGERDPQSGIYLQRGLIIFAL-------------IWIVAGWFDLFGMSMANG--------AHIAGLAVGLAMAFVDSLN........................ 181
9 -5.380d2o5ha1 d.363.1.1 (A:1-131) Hypothetical protein NMB0513 {Neisseria meningitidis [TaxId: 487]}  ali model 3D-neighbors follow..  13  5....................................................................................NNHDVHKRYQDRLEEDVEFTINYELLSCLWSTIKDFSSDFEEKTEAFFILFKELLRRGHLKLQRD------GQIIGHTPEEWEQIFREV.. 88
10 -5.330d1ou5a2 d.218.1.4 (A:1-150) tRNA CCA-adding enzyme, head domain {Human (Homo sapiens), mitochondrial [TaxId: 9606]}  ali model 3D-neighbors follow..  9  16......................................LKSLTELFVKENHELRIAG---GAVRDLLNG--VKPQDIDFATTATPTQMKEMFQSAGIRMINNRGEKHGTITARLHEENFEITTLRERRDLTINSMFLGFDGTLFDYFNGYEDL...................... 147
FFAS is supported by the NIH grant R01-GM087218-01
1 4 7 2 5 8   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Pawlowski K, Pio F, Chu Z, Reed JC, Godzik A. PAAD - a new protein domain associated with apoptosis, cancer and autoimmune diseases. Trends Biochem Sci. 2001 Feb;26(2):85-7.