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Query: [V] KOG1716 Dual specificity phosphatase, from COG1018

Results of FFAS03 search in SCOP207
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MRKRERENPCSICGHYHKYEEGEVCGVCGHCMPVSSDTVAPQQVHVSAFPSEILPEFLYLGSYDNASRSELLKTQGISRVLNTVPMCQNLYRNSFTYHGLDNEKVLQFDDAIKFLDQCEKDKARVLVHCMSGKSRSPAVVVAYLMKRKGWRLAESHQWVKQRRPSTDISPGKYLDFGLETYLLFLKLLLIAFSLYTEFYQQLQEFEQGIFGSEMMSAMNINDAPTFGFGFPKIDNQAQAPVFNNAPTSSIFSSPASSIPPQEFTFGATPPKPTTGGDIAMDGSLast
1 -66.200d2wgpa_ c.45.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  27  2...............................................GGIAQITS-SLFLGRGSVASNRHLLQARGITCIVNATIEIPNFNWPQFEYVKVPLADMPYFDTVADKIHSVSRKHGATLVHCAAGVSRSATLCIAYLMKFHNVCLLEAYNWVKARRPV--IRPNVGFWRQLIDYERQLFGKSTVKMVQTPYGIVPDVYEKE........................................................................... 165
2 -66.200d2hcma1 c.45.1.0 (A:2-158) automated matches {Mouse (Mus musculus) [TaxId: 10090]}  ali model 3D-neighbors follow..  24  6.............................................APPPFARVAP-ALFIGNARAAGATELLVRAGITLCVNVSRQQPGPRAPGVAELRVPVFDLTHLEPTCAAMEAAVRDGGSCLVYCKNGRSRSAAVCTAYLMRHRGHSLDRAFQMVKSARPV--AEPNLGFWAQLQKYEQTLQAQAILPR.......................................................................................... 156
3 -66.000d2g6za1 c.45.1.0 (A:178-320) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  36  1................................................GPVEILP-FLYLGSAYHASKCEFLANLHITALLNVSRRTSEACMTHLHYKWIPVEDSSHFQEAIDFIDCVREKGGKVLVHSEAGISRSPTICMAYLMKTKQFRLKEAFDYIKQRRSM--VSPNFGFMGQLLQYESEILPS............................................................................................... 143
4 -65.800d2nt2a_ c.45.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  32  2.................................................PTQIFE-HVFLGSEWNASNLEDLQNRGVRYILNVTREIDNFFPGVFEYHNIRVYDLAYWNDTYKFISKAKKHGSKCLVHSKMGVSRSASTVIAYAMKEYGWNLDRAYDYVKERRTV--TKPNPSFMRQLEEYQGILLA................................................................................................ 142
5 -64.500d3s4ea1 c.45.1.0 (A:65-206) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  28  2.................................................VGVIKP-WLLLGSQDAAHDLDTLKKNKVTHILNVAYGVENAFLSDFTYKSISILDLSYFPECFEFIEEAKRKDGVVLVHSNAGVSRAAAIVIGFLMNSEQTSFTSAFSLVKNARPS--ICPNSGFMEQLRTYQEGKES................................................................................................ 142
6 -64.200d1zzwa_ c.45.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  28  2...............................................AELTPILP-FLFLGNEQDAQDLDTMQRLNIGYVINVTTHLPLYHKGLFNYKRLPATDRQYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKHTRMTMTDAYKFVKGKRPI--ISPNLNFMGQLLEFEEDLNNG............................................................................................... 147
7 -62.500d1wrma1 c.45.1.0 (A:1-154) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  21  1.............................................MGNGMNKILP-GLYIGNFKDARDAEQLSKNKVTHILSVHDSARPMLEG-VKYLCIPAADTRHFKESIKFIHECRLRGESCLVHCLAGVSRSVTLVIAYIMTVTDFGWEDALHTVRAGRSC--ANPNVGFQRQLQEFEKHEVHQYRQWLKEE....................................................................................... 153
8 -60.900d2r0ba_ c.45.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  29  1..............................................RREMQEILP-GLFLGPYSSASKLPVLQKHGITHIICIRQNIEANFQQLFRYLVLDIADIRFFPMTKEFIDGSLQMGGKVLVHGNAGISRSAAFVIAYIMETFGMKYRDAFAYVQERRFC--INPNAGFVHQLQEYEAIYLA................................................................................................ 151
9 -60.600d2f4da_ c.45.1.1 (A:) VH1-related dual-specificity phosphatase, VHR {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  29  22..............................................SQPCNEVTP-RIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFYKDSGITYLGIKANDSAYFERAADFIDQAAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNRE---IGPNDGFLAQLCQLNDRLAKEGKLKP.......................................................................................... 180
10 -59.900d2j16a_ c.45.1.0 (A:) automated matches {Baker`s yeast (Saccharomyces cerevisiae) [TaxId: 4932]}  ali model 3D-neighbors follow..  22  2..............................................PKGPLLVLPEKIYLYSEPTVKE-----LLPFDVVINVAEEANDLRMQVPAVEYHHYRWALDLPSLTSIIHAATTKREKILIHCQCGLSRSATLIIAYIMKYHNLSLRHSYDLLKSRADK--INPSIGLIFQLMEWEVALNAK............................................................................................... 142
11 -59.700d4hrfd1 c.45.1.0 (D:61-209) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  28  1................................................HADEVWP-GLYLGDQDMANNRRELRRLGITHVLNASHSRWRGTPEGIRYLGVEAHDSIHFQTAADFIHRASQPGGKILVHSAVGVSRSATLVLAYLMLYHHLTLVEAIKKVKDHRG---IIPNRGFLRQLLALDRRLRQG............................................................................................... 148
12 -28.300d1ohea2 c.45.1.1 (A:199-380) Proline directed phosphatase CDC14b2 {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  19  19..................................................NWIIPDRF-IAFCGPHSRIQYFKNHNVTTIIRLNKDAKRFTDAGFDHHDLFFADTPTDAIVKEFLDICENAEGAIAVHSKAGLGRTGTLIACYIMKHYRMTAAETIAWVRICRPGSVIGPQQQFL--VMKQTNLWLEGDYFRQKLK....................................................................................... 181
13 -25.900d1fpza_ c.45.1.1 (A:) Kinase associated phosphatase (kap) {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  17  37.................................................................QKDTEELKSCGIQDIFVFCTR-DLYQQCGIITHHHPIADIASCCEIMEELTTCLKNYRKTLIHSYGGLGRSCLVAACLLLYLDTISPEQAIDSLRDLRGSGAIQTIKQ-YNYLHEFRDKLAAH............................................................................................... 175
14 -25.100d1rxda_ c.45.1.1 (A:) Protein tyrosine phosphatase type IVa {Human (Homo sapiens), pr-1 [TaxId: 9606]}  ali model 3D-neighbors follow..  20  1.................................................PVEV-MRFLITHNPTNAT-IEELKKYGVTTIVRVCEDTTLVEKEGIHVLDWPFDDPPSNQIVDDWLSLVEEPGCCIAVHCVAGLGRAPVLVALALIEG-GMKYEDAVQFIRQKRRGAFNSKQLLY---LEKYRPKMRLR............................................................................................... 151
15 -21.000d1i9sa_ c.45.1.1 (A:) mRNA capping enzyme, triphosphatase domain {Mouse (Mus musculus) [TaxId: 10090]}  ali model 3D-neighbors follow..  14  42.............................................................HPSMLSNYLKSLKVKMSLLVDLTNTSRFYDRNDIKYIKLQCKGECPTTENTETFIRLRSPPELIGVHCTHGFNRTGFLICAFLVEKMDWSIEAAVATFAQARPPGIYKGD--YLKELFRRYGDIEEAPPPPVL......................................................................................... 185
16 -17.000d2q47a1 c.45.1.1 (A:52-202) Putative phosphatase At1g05000 {Thale cress (Arabidopsis thaliana) [TaxId: 3702]}  ali model 3D-neighbors follow..  14  10....................................................MVDNGIFRSGFPDSANFSFLQTLGLRSIIYLCPEPYP----RLFQFGIEGNKEPFVNIPDHKIRMADEKNHPVLIHCKRGKHRTG-CLVGCLRKLQKWCLTSIFDEYQRFAAAKARVSDQRFMEIF......................................................................................................... 147
17 -14.300d3mmja_ c.45.1.4 (A:) Myo-inositol hexaphosphate phosphohydrolase (phytase) PhyA {Selenomonas ruminantium [TaxId: 971]}  ali model 3D-neighbors follow..  11  164............................................................................VRRVQKVQTEQEVAEAAGMRYFRIAATDPENIDRFLAFYRTL-PQDAWLHFHSEAGVGRTTAFMVMTDMLKNPSVSLKDILYRQHEIGGFYYGEFPIKTKDIEQFYRYVQENRADG........................................................................................... 298
18 -12.500d1d5ra2 c.45.1.1 (A:14-187) Phoshphoinositide phosphatase Pten (Pten tumor suppressor), N-terminal domain {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  17  23...............................................GFPAERLEG-VYRNNIDDVVRFLDSKHKNHYKIYNLCAE-TAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQDNHVAAIHCKAGKGRTGVMICAYLLHRGKFKAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSYLLKNH.............................................................................................. 172
19 -12.300d4yaaa_ c.45.1.2 (A:) Protein-tyrosine phosphatase YopH, catalytic domain {Yersinia enterocolitica [TaxId: 630]}  ali model 3D-neighbors follow..  15  58....................................................LNANYITIACQYPLQSQRMLAENRTPVLAVLASGMPDYFRQSGTYGSITVESSEVTKALASLVDQTAESKLRPVIHCRAGVGRTAQLIGAMCMNDSRNSQLSVEDMVSQMRVMVQKDEQLDVLIKLAE....................................................................................................... 273
20 -12.000d1g4us2 c.45.1.2 (S:297-539) SptP tyrosine phosphatase, catalytic domain {Salmonella typhimurium [TaxId: 90371]}  ali model 3D-neighbors follow..  14  66.....................................................................KMLLEKECSCLVVLTSQLPPYFRGSYTFGEVHTNSQK--DQLEYLADRVKNDKHLPMIHCLGGVGRTGTAAALVLKDNPHSNLEQVRADFRDSRNMLEDASQFVQLKAMQ........................................................................................................ 238
21 -11.500d1ywfa1 c.45.1.5 (A:4-275) Phosphotyrosine protein phosphatase PtpB {Mycobacterium tuberculosis [TaxId: 1773]}  ali model 3D-neighbors follow..  18  12.............................................VADTATALRPGRLFRSSE-DDAGRATLRRLGITDVADVARRGPGRVPDGIDVHLLPFPDLA--DAATRYMTDLLAAGRPVLTHCFAGKDRTG-FVVALVLEAVGLDRDVIVDYLRSNDSVPQLRARI............................................................................................................... 200
22 -10.200d4az1a_ c.45.1.0 (A:) automated matches {Trypanosoma cruzi [TaxId: 5693]}  ali model 3D-neighbors follow..  10  8TKLSVQAQYERVQREFSLLLRQEDPRSISFATSLKNRHKNRYLDILANEATLY-PYYIFVACQAPVVQGAMLYEKKISLVIMVTKKADRYWPEEVQYTGWPDHGIPQ-TSLEALLTNVKNTTVPVVVHCSAGIGRTGTLIGAYAALTHDTTVYDVVSAMRRQRFMVQRMEQYFVIYLTL........................................................................................................ 282
23 -10.100d2oc3a_ c.45.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  13  155................................................................TLIKEKWLNEDIMLRTLKVTFQKESRSVYQLQYMSWPDRGVPS-DHMLAMVEEARRGPEPLCVHCSAGCGRTGVCTVDYVRQLPDFSLFDVVLKMRKQRPAVQTEEQYRFLYHTV........................................................................................................ 283
24 -10.000d1wcha_ c.45.1.2 (A:) Tyrosine-protein phosphatase, non-receptor type 13 (PTPL1) {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  11  171................................................................ALVRMQQLKGFVVRAMLEDIQTREVRHISHLNFTAWPDHDTPS-DDLLTFISYMRHRSGPIITHCSAGIGRSGTLILGLISQDLDFDISDLVRCMRLQRHMVQTEDQYIFCYQILYVLTRLQAEEEQ............................................................................................ 308
25 -9.900d4ri5a1 c.45.1.0 (A:628-908) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  13  160.............................................................................EMLVTNTQTGEEHTVTHLQYVAWPEHGVPDFLEFVNYVRSLRVDSEPVLVHCSAGIGRTGVLVMCLTERNLPIYPLDIVRKMRDQRAMVQTSSQYKFVCEAI........................................................................................................ 271
26 -9.870d4ikca1 c.45.1.0 (A:2661-2939) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  13  136.................................................PEDNKPVTVF-GDIVITKLMEDVQIDWTIRDLKIERHGDCMTVRQCNFTAWPEHGVPE-APLIHFVKLVRADTTPMIVHSSAGVGRTGVIALDHLTQHIN-DFVDIYGLVAELRSMVQNLAQYIFLHQCI........................................................................................................ 275
27 -9.690d2bzla_ c.45.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  8  157..........................................................YATTGLKVKHLLSGQERTVWH---------------LQYTDWPDHGCPE-QGFLSYLEEIQSRHPPIVVHCSAGVGRTGVLIIYCLEHNEKVEVPMMLRLLREQRMMIQTIAQYKFVYQVL........................................................................................................ 283
28 -9.660d3zm1a1 c.45.1.0 (A:248-525) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  15  156...............................................................................LSKVGQGNTERTVWQYHFRTWPDHGVPS-GGVLDFLEEVHHDAGPVVVHCSAGIGRTGTIVIDILIDIIRIDVPKTIQMVRSQRSMVQTEAQYRFIYMAV........................................................................................................ 271
29 -9.480d2i1ya_ c.45.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  15  17................DRLAKEWQALCAYQAEPNTCATAQGEGNIKKNRHPDFLPDYIYIATQGPLSHTQMVWESGCTVIVMLTPQCDRYWPDEFHFLSWPAEGTPA-RPLLDFRRKVNKRSCPIIVHCSDGAGRTGTILIDMVLNRMAIDIAATLEHVRDQRPLVRSKDQFEFALTAEEVNAILKA................................................................................................ 286
30 -9.240d2f71a_ c.45.1.2 (A:) Tyrosine phosphatase {Human (Homo sapiens), 1B [TaxId: 9606]}  ali model 3D-neighbors follow..  15  152..........................................................YTVRQLELENLTTQETREILH---------------FHYTTWPDFGVPESPASFNFLFKVREEHGPVVVHCSAGIGRSGTFCLLLMDKRKDPSSVDIKKVLLEMRKLIQTADQLRFSYLAV........................................................................................................ 273
31 -9.200d2cjza1 c.45.1.0 (A:258-536) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  10  133......................................................EEQVAYDGVEITVQKVIHTEDYRLRLISLKSGTEERGLKHYWFTSWPDQKTPD-PPLLHLVREVEEHCAPIIVHSSAGIGRTGCFICQQLRQEGVVDILKTTCQLRQDRGMIQTCEQYQFVHHMSLYEKQLS................................................................................................. 279
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 0 4 6   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Godzik A. cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences. Bioinformatics. 2006 May 26;