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Query: [M] KOG2388 UDP-N-acetylglucosamine pyrophosphorylase, from COG1018

Results of FFAS03 search in SCOP207
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MASTVDSNFFSSVPALHSNLGLLSPDQIELAKILLENGQSHLFQQWPELGVDDKEKLAFFDQIARLNSSYPGGLAAYIKTAKELLADSKVGKNPYDGFSPSVPSGENLTFGTDNFIEMEKRGVVEARNAAFVLVAGGLGERLGYNGIKVALPRETTTGTCFLQHYIESILALQEASNKIDSDGSERDIPFIIMTSDDTHSRTLDLLELNSYFGMKPTQVHLLKQEKVACLDDNDARLALDPHNKYSIQIQMDFSSMLVAATQLLCLKVFIQFLMEIHNSLMTSLVQAIPASLGVSATKQYHVNSLAVPRKAKEAIGGISKLTHVDGRSMVINVEYNQLDPLLRASGFPDGDVNCETGFSPFPGNINQLILELGPYKDELQKTGGAIKEFVNPKYKDSTKTAFKSSTRLECMMQDYPKTLPPTARVGFTVMDIWLAYAPVKNNPEDAAKVPKGNPYHSATSGEMAIYRANSLILQKAGVKVEEPVKQVLNGQEVEVWSRITWKPKWGMIFSDIKKKVSGNCEVSQRSTMAIKGRNVFIKDLSLDGALIVDSIDDAEVKLGGLIKNNGWTMESVDYKDTSVPEEIRIRGFRFNKVEQLEKKLTQPGKFSVEDLast
1 -103.000d1jvga_ c.68.1.5 (A:) UDP-N-acetylglucosamine pyrophosphorylase {Human (Homo sapiens), AGX2 [TaxId: 9606]}  ali model 3D-neighbors follow..  18  1.........................NINDLKLTLSKAGQEHLLRFWNELEEAQQVE--LYAELQAMNFEELNFFFQKAIEGFNQSSHQKNVDARMEPVPREVLGSATRDQDQLQAWESEGLFQISQNKVAVLLLAGGQGTRLGVAYPKGMYDVGLPSRKTLFQIQAERILKLQQVAEKYYGNK--CIIPWYIMTSGRTMESTKEFFTKHKYFGLKKENVIFFQQGMLPAM-SFDGKIILEEKNKVSMAPDGNGGLYRALAAQNIVEDMEQRGIWSIHVYCVDNVKVADPRFIGFCIQKGADCGAKVVEKTNPTEPVGVVCRVD----GVYQVVEYSEISLATAQKRSSDGR------LLFNAGNIANHFFTVPFLRDVVNVYEPQLQHHVAQKKIDTQGQLIKPDKPNGIKMEKFVDIFQFAKKFVVYEVLREDEFSPLKNA-------DSQNGKDNPTTARHALMSLHHCWVLNAGGHFIDENGSRLPAIPRSAGKSETITADVNHNLKDANDV-PIQCEISPLISYAGEGLESYVADKEFHAPLIIDENGVHEL...................................................... 516
2 -93.300d2yqca_ c.68.1.0 (A:) automated matches {Yeast (Candida albicans) [TaxId: 5476]}  ali model 3D-neighbors follow..  16  2........................KSQQQIIDSFKQANQDQLFQYYDSLTIDQQQE--FIDQLSTIE--EPAKLISTVEQAIQFSQTNSTSRNFTQLPNEQTASTLDLSKDILQNWTELGLKAIGNGEVAVLLMAGGQGTRLGSSAPKGCFNIELPSQKSLFQIQAEKILKIEQLAQQYLKSTKKPIINWYIMTSGPTRNATESFFIENNYFGLNSHQVIFFNQGTLPCFNLQGNKILLELKNSICQSPDGNGGLYKALKDNGILDDLNSKGIKHIHMYCVDNVKVADPIFIGFAIAKKFDLATKVVRKRDANESVGLIVLDQDN--QKPCVIEYSEISQELANKKDPQDS----SKLFLRAANIVNHYYSVEFLNKMIPKSQKYLPFHIAKKKIPSLNLTEPNGIKLEQFIFDVFPSVE-LNKFGCLEVDRLDEFSPLKNADGAKN--------DTPTTCRNHYLERSSKWVIQNGGVIDNQG-------------LVEVDSKTSYGGEGLEF................................................................................................ 472
3 -67.900d2icya2 c.68.1.5 (A:5-383) UDP-glucose pyrophosphorylase 2 (UDPGP 2) {Thale cress (Arabidopsis thaliana) [TaxId: 3702]}  ali model 3D-neighbors follow..  14  2...........................................ENLPQL----KSAVDGLTEMSESEKSGFISLV-------SRYLSGEAQHIEWSKIQTPTDEIVVPYEKMTPVSQDVAETKNLLDKLVVLKLNGGLGTTMGCTGPKSVIEVR--DGLTFLDLIVIQIENLNNKYG--------CKVPLVLMNSFNTHDDTHKIVEKYTNSN---VDIHTFNQSKYPRVVADEFVPWPGKTDKEGWYPPGHGDVFPALMNSGKLDTFLSQGKEYVFVANSDNLAIVDLTILKHLIQNKNEYCMEVTPKTLADVKGGTLISYE----GKVQLLEIAQVPDEHVNEFKSIE--------KFKIFNTNNLWVNLKAIKKLVEADALKMEIIPNPKEVDG-----VKVLQLETAAGAAIRFFDNAIGVNV----PRSRFLPVKAS-------------SDLLLVQSDLYTLVDGFVTR....................................................................................................................................... 378
4 -15.200d2icya1 b.81.1.4 (A:384-466) UDP-glucose pyrophosphorylase 2 (UDPGP 2) {Thale cress (Arabidopsis thaliana) [TaxId: 3702]}  ali model 3D-neighbors follow..  10  4...........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................TNPSNPSIELGPEF-KKVATFLSRFKSIPSIVELDSLKVSGDVWFGSSIVLKGKVTVAAKSGVKLEIRAVVENKNIN.......................................... 81
5 -10.700d1fxoa_ c.68.1.6 (A:) RmlA (RfbA) {Pseudomonas aeruginosa [TaxId: 287]}  ali model 3D-neighbors follow..  13  1...............................................................................................................................KRKGIILAGGSGTRL-LAISKQLLPV---YDKPMIYYPLSTLMLAG---------------EILIISTPQDTPRFQQLLGDGSNWGL---DLQYAVQPS----------------------PDGLAQAFLIGESFIGNDLS---------------------LVLGDNLYYGHDFH-ELLGSASQRQTGASVFAYHVLDPERYGVVEFDQGGKAISLEEKPLEPKSN-------YAVTGLYFYDQQVVDIA---------------------RDLKPSPRGELEITDVNRAYLERGQLSVEIMGRGYAWLDTGTHDSLLEAGQ................................................................................................................................................................ 236
6 -10.000d1hm9a2 c.68.1.5 (A:2-251) N-acetylglucosamine 1-phosphate uridyltransferase GlmU, N-terminal domain {Pneumococcus (Streptococcus pneumoniae) [TaxId: 1313]}  ali model 3D-neighbors follow..  13  1...............................................................................................................................SNFAIILAAGKGTRMKSDLPKVLHKV---AGISMLEHVFRSVGAIQ-----------------TVTVVGHKAELVEEVLAGQTEFVTQSEQL---VMMTEPILEGLSGHTLVIAGDTPLITGE------------------------------------SLKNLIDFHINHKNVATILTAETDNPFGYGRIV---RNDNAEVLRIVEQKDATDFEKQIKE----------------NTGTYVFDNERLFEALKN-------------------INTNNAQGEYYITDVIGIFETGEKVGAYTLKDFDESLGVNDRVALATAES................................................................................................................................................................ 236
7 -9.700d1yp2a2 c.68.1.6 (A:10-316) Glucose-1-phosphate adenylyltransferase small subunit, catalytic domain {Potato (Solanum tuberosum) [TaxId: 4113]}  ali model 3D-neighbors follow..  10  10..............................................................................................................................RSVLGIILGGGAGTRLYKKRAKPAVPLG--ANYRLIDIPVSNCL--------------NSNISKIYVLTQFNSASLNRHLSRAYASNMGGYKNEGFVEVLAAQQSPENPDWFQ-----------GTADAVRQYLWLFEEHTVLEYLILAGDHLYRMDYE----KFIQAHRETDADITVAALPMDEKRATAFGLMKIDEEGR----IIEFAEKPQGEQLQAMKVDTTDKRAKEMPFIASMGIYVISKDVMLNLLRDKFPGANDFVIPGATSLGMRVQEDIGTIEAFYNANLGITKKPVPDFSFYDRSAPIYTQPR.......................................................................................................................................................................... 307
8 -9.540d1i52a_ c.68.1.13 (A:) 4-diphosphocytidyl-2C-methyl-D-erythritol (CDP-me) synthase (IspD, YgbP) {Escherichia coli [TaxId: 562]}  ali model 3D-neighbors follow..  11  3...............................................................................................................................DVCAVVPAAGFGRRMQTECPKQYLSI---GNQTILEHSVHALLAHPRVKR------------VVIAISPGDSRFAQLPLANAGLKAAGDAQWVLVHDAARPCLHQDDLARLLALSETSRTGGILAAPVRDTMKRAEPGKNAIAHTVDRNGLWHALTPQFFPRELLHDCLTRALNEGATITDEASALEYCGFHPQLVEGRADNIKVTRPEDL................................................................................................................................................................................................................................................................................ 216
9 -9.510d4myba_ c.68.1.0 (A:) automated matches {Francisella tularensis [TaxId: 263]}  ali model 3D-neighbors follow..  8  1..............................................................................................................................SNKYVIIPAAGIGTRMQLDIPKQYYKLN--NGKTILDNTLVKFIDNPLFDK------------IFVAIAASDNFWNNSLYYNHDKIERKNDDWVFVHDAARPCVSIDSIIDLYE-----QTKSSHSQAGILAVRAYETVKQVTKNIVDNIWLAQTPQLSRLGQLEKAFDFCYSNNLVAKVTDEASALEMFGINPIVVECSKKNIKITTKDDL................................................................................................................................................................................................................................................................................ 220
10 -9.350d2e8ba_ c.68.1.8 (A:) Molybdenum cofactor biosynthesis protein MobA {Aquifex aeolicus [TaxId: 224324]}  ali model 3D-neighbors follow..  10  4........................................................................................................................RKGSLSKVNTCYVLAGGKSKRFGED--KLLYEIK---GKKVIERVYETAKSVKEVYIVAKDREKFSFLNAPVVLDEFEESASIIGL--YTALKHAKEENVFVLSGDLPLMKKETVLYVLENFKEPVS........................................................................................................................................................................................................................................................................................................................................................................... 124
11 -9.220d2cu2a2 c.68.1.20 (A:1-268) Putative mannose-1-phosphate guanylyl transferase (GDP)/mannose-6-phosphate isomerase TTHA1750 {Thermus thermophilus [TaxId: 274]}  ali model 3D-neighbors follow..  11  2...............................................................................................................................KTYALVMAGGRGERL--DRPKPFLPL--FEGKTLLEATLERLAPLVPPER------------TLLAVRRDQEAVARPYADGIRLL------LEPLGRDTAGAVLLGVAEALKEGAERLLVLPA--------------------------DHYVGDDEAYREALATMLEAAEEGFVVALGLRPTRPETEYGYI-RLGPREGAWYRGEGFVE---------KPSYAEALEYIRKGYVWNGGVFAFAPATMAELFR------------RHLPSHHEALERLLAGASLEEVYAGLPKISIDYGVMEKAERVRVVLGR.......................................................................................................................................................................... 250
12 -9.080d1e5ka_ c.68.1.8 (A:) Molybdenum cofactor biosynthesis protein MobA {Escherichia coli [TaxId: 562]}  ali model 3D-neighbors follow..  14  1.............................................................................................................................MTTITGVVLAGGKARRMG-GVDKGLLELN---GKPLWQHVADALMTQLSHVVVNANRHQEIYQASGLKVIEDSLADYPGPLA-LSVMQQEAGEWFLFCPCDTPYIPPDLAARLNHQRKDAPVVWVHDGE.................................................................................................................................................................................................................................................................................................................................................................... 126
FFAS is supported by the NIH grant R01-GM087218-01
1 4 7 9 3 8   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Godzik A. cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences. Bioinformatics. 2006 May 26;