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Query: IDP92021 adenosine/AMP deaminase domain containing protein [Toxoplasma gondii ME49] TGME49_005720 [Toxoplasma gondii ME49], from CSGID

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MSPSATLPSFEEIASLPKIELHAHLFGSIRVPVLEEIRQRAAEEHKQTTESCYGANADEAAANVARIEGKCIDIGDAFAYFSAVYEIVRRKDDIVYALRRVLEDFSQDNVVYLELRTTLKTIPEEGIDPDNYVALLVEELKSAEKQYPMIVRLILSLNRSRLTSEVETREETVKILDLVAKYPEWIVGVDIAGDPRKGNILPALEVLEKEVMNPSGAHHGKLKVTVHTSEVEGSEKETKAVLKLAPHRIGHGCYLAVDQREFLLKEKICVEICPSSNMCTLNLRDLKDHPFSYYYGKKVLSNAVCICTDDIGLFDTSLSKELHVLSQAYNLSLSDVMDLQRSALAAAFCRDEDKAKIEEKFFRPHILast
1 -92.200[F] COG1816 Adenosine deaminase  ali follow..  16  1...MSNLPIYNFIRKLPKCEHHVHLEGCLSPDLVFRLAKKNGITLPSDDAAYT------TPSTLLASYEHFGCLDDFLRYYYIAVSVLIEASDFEALAYEYFSIAHSQGVHHAEVFFDPQTHTSRGISYDVVVSGFSAACERANRDFGMSTNLIMCFLRHLPSEAAHETFAE--ALKRNDFENGIVAGVGLDSSEVDFPPELFQ-------EVYKLAAEKGIRRTGHAGEEGDPSYIRSGLDNLSLQRIDHGIRLVEDKMKRVAEENIMLTMCPLSNLKLRCVNSIAELPVREFLEAGV---PFSINCDDPAYFGGYTLENYFAIQKHFNLTVKEWVFIANAAINGSWISGKRKEELLSSVQKCV. 346
2 -70.700[F] KOG1097 Adenine deaminase/adenosine deaminase  ali follow..  18  113LTKVKKSPLFQILRRMPKAALKAHDTSMCSSRVVIEITYRDNLWVCTTQNGCRVEEMRFSMYPLASFTTNAHAWRHMMGIFGLLDGLLQYAPVWGDYYYNALKEFYADGVQYLEVRSVLPQLYSSRMPKRETVQIYKDTLERFKKEHPIDSKLIYAPIRHVQPELVGEYIKE--CTELNKEFPSFVVGFDLVGQEDVGHPLSN-------FAAELLKLPDHIHFYFHAGQTNWYQNLLDAIV-LGTKRIGHGYTITKHPMRLAKYLNIALEVCPVSNQVLQLGSDYRSHPAATLIAENV---PMVIASGSPGFWRAALSHDFYMAFLGIAADLKFLKRTAKNSIKYSSLKDEAKAEAMEKWKKQW. 519
3 -51.800[F] KOG1096 Adenosine monophosphate deaminase  ali follow..  14  425...HEQKGVSHRDFYNIRVDTHIHAASSMNQKHLLRFIKKKIKTEADDMLDVHADRNTFHRFDKFNTKYNPVGESTLREIFIKTDNYVGG-KYFADLLKEVLSDLEDSKYQHAEPRLSIYGRSKN--NFDDMLDNLFTPLFEVTNDPSSHPELHLFLQQISGIDSVDD-ESKHEFVNFDRSTPCPPEYTDLENPPYNYYLFYMYRNICALNAFRRARGLNTFALRPHCGEAGHVSHLLTGY--LTSESIAHGILLRKVPQYLYYLTQIGIAMSPLSNNSL--FISYQRNPLPEYLQKGL---NVSLSTDDPLQFHEALMEEFSIAAQVWKLSSCDMCELARNSVMQSGFEDKVKIHWLGPNYKEE. 849
4 -14.600[FQ] KOG3968 Atrazine chlorohydrolase/guanine deaminase  ali follow..  12  75...............MP-VDTHIHASQYSFAGSSIDL-----------------------------------PLLEWLTKYTFPAEHFQNIDFAEEVYTRVVRRTLKNGTTTACYFAT----------HTDSSLLLADITDKFGQRAFVGKVCM-DTFPEYKETTEESIKETERFVSEMLQKNYSRVKPIVT------PRFSLSCSETLMGELGNIAKTRDLHIQSHISENKNYTSVYDKNNLLTNKTVAHGCYLSAEELNVFHERGASIAHCPNSNLSLSS-------NVLEVLKHEV---KIGLGTDVAGGYSYSMLDAIRRAVNEKSLTLKEVFRLATLGGSQALGLDGEIGNF......... 389
5 -13.200[Q] COG1228 Imidazolonepropionase and related amidohydrolases  ali follow..  10  73...............TP-VDPHTHLALKQQGVPYLEILKNGG---------------------------------GILATVEATRAA--SEEELITKAICHLNRMLSYGVTTIEAKSGYGLDRETEWKQLRAAKAVGEQHPIDIVSTFLGAHAIPTSHRNDPDRFLDEMADMLGEIK-----EQNLAEFVDI------FTETGVFTVEQSRTFLQKAKERGFGLKLHADEIDPLGGAELAGE-LGAISADHLVGASDQGIQKMAAAGTIACLLPGTTFYLGK-------RARDMIDQGL---AVTISTDFNPGSSPNLQLIMSIAALRLKMTPEEIWHAVTVNGAHAIGRGDTAGQL......... 374
6 -11.500[FR] COG0402 Cytosine deaminase and related metal-dependent hydrolases  ali follow..  10  56...............MP-VDTHRHVWESLLRHIGTDW-----------------------------------TLLTYLDYYGNLGSMLTPEDSYIANLWGALEAIDAGVTTVLDWSM---------LETPEHADASIKGLQAAGIRAVFAHGTPGYETYWSRDSEVRHPKDAKRVKKEYFQSDDQLLTMALA------IRGPEFSSWEVTLDDIQLARELDAIASMHIGFGTWGPHDRSITRMREAGLLDHVNRIQPHEYEYIAESGASLSVTPEVEMMMGH-------ATGYLHKHRG---LVTLGVDVVVATAGDMFAQMKFALEQLKMTTNDVLTFATLNGAKALKLDDKIGTL......... 367
7 -10.400[R] COG1099 Predicted metal-dependent hydrolases with the TIM-barrel fold  ali follow..  8  2......................................................................................YFDSHLHSEGLGFSELVKLKENGIKEVCSLAFFPVKPKYPQTMIDVFRKLTEFEPLRCEAAGVKMHPAVGIHPRCIPPDYEFVLGYLE--------EGEWVAFGEIGLELVTDEEI-----EVLKSQLELAKRMDVPCIIHTPRGNKLKATRKTLEILESLDFPADLHVNFETLDMVLETEIGLTVQPGKLSAEDAARIVAEHGPERFM----------LNSDAGYRDVEITTVAEAAVKIEEAVGREEMEKVARENARKFL.................. 246
8 -10.200[L] KOG3020 TatD-related DNase  ali follow..  10  138..............NVPYIDSHCHTD----------------YMYTSLARRKTNSNEGLLDWIEKYPRAFPKCFFGLIANFIKPDLFVDVKGNSSYDVEWIVKELASPLYLGTTWGCHP--HFAQHWGRMGVFWTTMEYILSDAEE-------------------------------------WKVLAVGECGIDLHRCESELEVQKDVFEKHVALAFKFKLPLVIHCRNGSKGRAEEECLQILKKKMHRHCFTENWEVAQMWLKQCPDVHFGFTPAVFAPQIQAIRNIPLDRIL----------LETDGPYFK-GMAIATASKIAEIKNLPIEEVLRATFNNTRRVY.................. 432
9 -9.750[R] COG1831 Predicted metal-dependent hydrolase (urease superfamily)  ali follow..  12  1...............MIILDNHFHVD------------------------------------------------------------------PINGLFLEAVKQFHRAGGTHLVVVYKSAHDYGFGGDFMRAMDFHVELVEIINKETPVKAYAVVGVH-ARARGIEYAKREVMKALEHAQRLDGKAIGIGEVGPHYPVPEEIWEASIEIMKYAMALAKEADCAVQLHTESFDEERELGRYVREVGIKPYRVVKHFSPPLVKVAEEVGIFPSIIASRKNIEEAIKQGTR---------------FLMETDYIDD--KTVPRRTKELLQKGILTEDDVYRIHVENPEKVY.................. 275
10 -8.030[R] COG1574 Predicted metal-dependent hydrolase with the TIM-barrel fold  ali follow..  11  95...............LP-IDNHTHWDGVRSLADAMDMLKRQVAITPAPTEHQFAEKRLPTIEEINAVAPDTPVFLLHLYDRALLNGAALRAVGYTRDTPNLLLAKPNAGILYSTLAKGPRELNRLGVTG-QNYPDDYEVIQKLSDENQMTVRLAYNLFTQKPKEEKQDFLNWTQSVK--YKQGNDYFRHNGAGEMLVFSAADFEDFRGELEEVLRVLAENRWPWRLHATYDETISRALDVFEKVNKDFFDHAETISDRSIDRIAALGGGIATQHR---RYGHGVAEATPPIRRMLDKGV---NVSAGTDATRVASYNPWVSLSWMVTGKTLDRETALRMWTEKVTWFSNEEGKKGRI......... 530
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 3 1 6   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Dunbrack RL Jr, Dunker K, Godzik A. Protein structure prediction in biology and medicine. Pac Symp Biocomput. 2000;(12):93-4.