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Query: IDP00106 gene: mdaB; modulator of drug activity B NT01SF3707 [Shigella flexneri 2a str. 2457T], from CSGID

Results of FFAS03 search in CSGID
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MSNILIINGAKKFAHSNGQLNDTLTEVADGTLRDLGHDVRIVRADSDYNVKAEVQNFLWADVVIWQMPGWWMGAPWTVKKYIDDVFTEGHGTLYASDGRTRKDPSKKYGSGSLVQDKKYMLSLTWNAPMEAFTEKDQFFHGVGVDGVYLPFHKANQFLGMEPLPTFIANDVIKMPDVPRYTEEYRKHLVEIFGLast
1 -102.000IDP00106 gene: mdaB; modulator of drug activity B NT01SF3707 [Shigella flexneri 2a str. 2457T]  ali  100  1MSNILIINGAKKFAHSNGQLNDTLTEVADGTLRDLGHDVRIVRADSDYNVKAEVQNFLWADVVIWQMPGWWMGAPWTVKKYIDDVFTEGHGTLYASDGRTRKDPSKKYGSGSLVQDKKYMLSLTWNAPMEAFTEKDQFFHGVGVDGVYLPFHKANQFLGMEPLPTFIANDVIKMPDVPRYTEEYRKHLVEIFG 193
2 -101.000IDP00129 gene: mdaB; NADPH-specific quinone oxidoreductase NT01ST3985 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  90  1MSNILIINGAKKFAHSNGQLNDTLTEVADGLLRDLGHQVKIVRADSDYDIKEEVQNFVWADVVIWQMPGWWMGAPWTVKKYMDDVFTEGHGTLYASDGRTRSDAAKKYGSGGLVQGKKYMLSLTWNAPMEAFTEKDQFFHGVGVDGVYLPFHKANQFLGMDALPTFIANDVIKMPDVPRYTAEYRKHLSEIFA 193
3 -99.800IDP00511 gene: mdaB; putative modulator of drug activity YPO0670 [Yersinia pestis CO92]  ali follow..  65  1MSNVLIINAMKEFAHSKGALNLTLTNVAADFLRESGHQVKITTVDQGYDIESEIENYLWADTIIYQMPAWWMGEPWILKKYIDEVFTDGHGRLYQSDGRTRSDATKGYGSGGLIQGKTYMLSVTWNAPREAFTDPEQFFHGVGVDGVYLPFHKANQFLGMKPLPTFMCNDVIKQPDIEGDIARYRQHLAENVN 193
4 -76.500IDP02003 glutathione-regulated potassium-efflux system ancillary protein KefG [Yersinia pestis CO92] YPO0190 [Yersinia pestis CO92]  ali follow..  14  5PPKVLLLYAHPESQDS--VANRVLLQPVQQLEHVTVHDLYAHYPDFFIDIHHEQQLLRDHQVIVFQHPLYTYSCPALLKEWLDRVLARGFANGV---------------GGHALTGKHWRSVITTGEQEGTYRIGGY--NRYPMEDILRPFELTAAMCHMHWINPMIIYWARRQKPETSHAQAYVQWLQSPLT 180
5 -75.600IDP01886 gene: yabF; glutathione-regulated potassium-efflux system ancillary protein KefF [Salmonella typhimurium LT2] STM0085 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  21  2...ILIIYAHPYPHHSHA--NKRMLEQAGTLENVEIRSLYHLYPDFNIDVAAEQEALSRASLIVWQHPMQWYSVPPLLKLWMDKVLTHGWAYGH---------------GGTALHGKHLLWAVTTGGGENHFAIGS----HPGFDVLSQPLQATALYCGLKWLSPFAMHCTFICDDDTAQARQYKQRLLAWQE 172
6 -74.500IDP01979 gene: yheR; glutathione-regulated potassium-efflux system ancillary protein KefG [Salmonella typhimurium LT2] STM3458 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  17  4PAKVLLLYAHPESQDS--VANRVLLKPAIQHNNVTVHDLYARYPDFFIDTPYEQALLREHDVIVFQHPLYTYSCPALLKEWLDRVLSRGFASGP---------------GGNQLVGKYWRSVITTGEPESAYRYDAL--NRYPMSDVLRPFELTAAMCRMHWMPPIIVYWARRQSPQTSHAKAYGEWLANPVS 179
7 -43.900IDP02263 hypothetical protein GBAA0966 [Bacillus anthracis str. `Ames Ancestor`] GBAA0966 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  13  1MNKTLIINAHPDTSSVSIKVFKHFLESYKEL-ISNNETIEQINLYDD-RMSEILQQFKSANTYVIVLPLHNFNIPSKLKDYMDNIMIARETFKYTETGSV----------GLLKDGRRMLVIQASGGIYTNDDW------YTDVEYSHKYLKAMFNFLGIEDYQIVRAQGTAVLDPTENAYKEVEEAASRLAN 212
8 -42.200IDP04320 gene: acpD; acyl carrier protein phosphodiesterase [Yersinia pestis CO92] YPO2323 [Yersinia pestis CO92]  ali follow..  15  1MSKVLVLKSSILATSSQSQLADFFVEQWQAADQITVRDLAAQPIEALALSDELIAELQANDVIVIAAPMYNFNIPTQLKNYFDMIARAGVTFRYTEKGPE-----------GLVTGKRAIILTSRGG----------IHKDTPTDLVVPYLRLFLGFIGITDVEFVFAEGIAYGPEVTKAQADAKTLLAQVVA 200
9 -41.100IDP04035 azoreductase [Bacillus anthracis str. Sterne] BAS5262 [Bacillus anthracis str. Sterne]  ali follow..  15  1MTKVLFVKANNRPQAVSVKLYEAFLASYKEADTVVELDLYKEELKAVAVADKYLNQFLEADKVVFGFPLWNLTIPAVLHTYIDYLNRAGKTFKYTPEGPV-----------GLIGDKKIALLNARGGVYSEGPAAE-------VEMAVKYVASMMGFFGATNMETVVIEGHNQFPDKEEIITAGLEEAAKVAN 206
10 -19.800IDP00950 gene: wraB; TrpR binding protein WrbA STM1119 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  11  1MAKILVLY------YSMYGHIETMAHAVAEGAKKVDGAEVIIKRKTQNAPVATPQELADYDAIIFGTPTRFGNMSGQMRTFLDQT--------------------GGLWASGSLYGKLGSVFSSTGT.................................................................. 116
11 -17.900IDP95068 azoreductase [Clostridium perfringens B str. ATCC 3626] AGH15624 [Clostridium perfringens B str. ATCC 3626]  ali follow..  11  1MK-VLLVNGSPNKEGCTYTALKEVSKTLEENIDTEIFQVGNKPIGMKDGVNEFVEKAKDADGFVFGSPVYYAAASGSITSFLDRAFYS---------------------GGKHMAFKPGAVICSARRAGTTSTLDQLSKYLTICNMPVVSSQYWNMVHGNTP------EKVKKDLEGMQTMRVLGRNMAWLIK 181
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Liu T, Rojas A, Ye Y, Godzik A. Homology modeling provides insights into the binding mode of the PAAD/DAPIN/pyrin domain, a fourth member of the CARD/DD/DED domain family. Protein Sci. 2003 Sep;12(9):1872-81.