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Query: IDP02252 gene: tsr2; putative methyl-accepting chemotaxis protein [Yersinia pestis CO92] YPO1229 [Yersinia pestis CO92], from CSGID

Results of FFAS03 search in CSGID
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MLDSIRSRILAACIIIVAGSLAINTFLNYSVANKYNNSAIDNTLTALTVSHSVSIAEWVASKTQMIMSLKDSALTADPLAALKQVAAAGGFINVYIGYADKTAIFSNPDGIPADYDPTGRPWYLQAVNAGKPVVTPPYIDAGTQQLVVTFAWSIVQDGVLKGVIAADVTMGSVIANVNAIHPTDNSFGMLIGADGTIIAHPETLLTLKPLADIAPNLNLQTLLTATVPVSTDISGSSKLLLAQAVPGTQWFTVVALDKSQATAGIHSLLTTSLVTLVIIIFISAGVIALITQRALTPLTHIQQAMDAISSGSADLTQRLPIEGRDEVAQIARSFNQFADKLSLVMAQIRGTSESVRVAANEIAAGNQDLSGRTESAAASLQQTSAALEQISATVAQSASAARQANNAVFSASEDASRGGDVITKVITTMESIEKASGKIGDITSVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRILAQRSAQAAKEIKALIESTVSSVASGSSQVRQASNAMTDIVSSVSDVTTIMSEITNAADEQMRGIHEINSAVAQLDTMVQQNAALVQESTAASAALQAQAADLTDTVNQFKILast
1 -127.000IDP02252 gene: tsr2; putative methyl-accepting chemotaxis protein [Yersinia pestis CO92] YPO1229 [Yersinia pestis CO92]  ali  100  1MLDSIRSRILAACIIIVAGSLAINTFLNYSVANKYNNSAIDNTLTALTVSHSVSIAEWVASKTQMIMSLKDSALTADPLAALKQVAAAGGFINVYIGYADKTAIFSNPDGIPADYDPTGRPWYLQAVNAGKPVVTPPYIDAGTQQLVVTFAWSIVQDGVLKGVIAADVTMGSVIANVNAIHPTDNSFGMLIGADGTIIAHPETLLTLKPLADIAPNLNLQTLLTATVPVSTDISGSSKLLLAQAVPGTQWFTVVALDKSQATAGIHSLLTTSLVTLVIIIFISAGVIALITQRALTPLTHIQQAMDAISSGSADLTQRLPIEGRDEVAQIARSFNQFADKLSLVMAQIRGTSESVRVAANEIAAGNQDLSGRTESAAASLQQTSAALEQISATVAQSASAARQANNAVFSASEDASRGGDVITKVITTMESIEKASGKIGDITSVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRILAQRSAQAAKEIKALIESTVSSVASGSSQVRQASNAMTDIVSSVSDVTTIMSEITNAADEQMRGIHEINSAVAQLDTMVQQNAALVQESTAASAALQAQAADLTDTVNQFKI 595
2 -95.100IDP02460 gene: cheD; methyl-accepting chemotaxis protein [Yersinia pestis CO92] YPO1675 [Yersinia pestis CO92]  ali follow..  49  183..................................................................................................................................................................................................................................................................EDSNQSFSFAMGVVITVLVVVLVMMLLVWLGMQQILIHPLNHLIAHIKHIANG--DLTQNIEVHGRNEVGTLAASLKHMQSELVTIVGEVRVGADAIYSGASEIAVGNNDLSARTEQQAASLEETAASMEQLTATVKQNAENARQASQLALSASETAQKGGKVVADVVQTMHEIAGSSQKIADITSVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRNLAQRSAQAAKEIKGLIDDSVNRVDLGSVLVESAGETMGDIVNAVTRVTDIMGEIASASDEQSRGIDQIGQAVAEMDRVTQQNASLVEESASAAASLEEQASMLTQAMSVFVL 517
3 -95.000IDP02090 gene: tcp; methyl-accepting transmembrane citrate/phenol chemoreceptor [Salmonella typhimurium LT2] STM3577 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  49  182..................................................................................................................................................................................................................................................................DQNQSSFTQMQWTLGIILLIVLIVLAFIWLGLQRVLLRPLQRIMAHIQTIADG--DLTHEIEAEGRSEMGQLAAGLKTMQQSLIRTVSAVRDNADSIYTGAGEISAGSSDLSSRTEQQASALEETAASMEQLTATVRQNTDNARQATGLAKTASETARKGGRVVDNVVSTMNDIAESSEKIVDITSVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRTLASRSAQAAKEIKVLIENSVSRIDTGSTQVREAGETMKEIVNAVTRVTDIMGEIASASDEQSKGIEQVAQAVSEMDSVTQQNASLVEESAAAAAALEDQANELRQAVAAFRI 516
4 -94.600IDP01089 gene: tsr; methyl-accepting chemotaxis protein I STM4533 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  49  183..................................................................................................................................................................................................................................................................EDNNSSYNQAMWVLVSVLIAVLVVIIAVWFGIKLSLIAPMNRLIESIRHIASG--DLVKRIDVEGSNEMGQLAENLRHMQSELMRTVGDVRNGANAIYSGASEIAMGNNDLSSRTEQQAASLEETAASMEQLTATVKQNAENARQASHLALSASETAQKGGKVVDNVVQTMRDIASSSQKIADIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRNLAQRSAQAAREIKSLIEDSVSRVDVGSTLVESAGETMDEIVNAVTRVTDIMGEIASASDEQSRGIDQVGLAVAEMDRVTQQNASLVEESAAAAAALEEQASRLTQAVAVFRI 517
5 -93.700IDP01940 gene: trg; methyl-accepting chemotaxis protein III [Salmonella typhimurium LT2] STM1626 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  43  195..................................................................................................................................................................................................................................................................EQAYQRTRLGMMFMIGAFTLALVLTLMTFMVLRRTVIQPLQQSASRIERIAAG--DLTMADEPTGRSEIGRLSHHLQQMQHALQQTVGAVRQGAEEIYRGTSEITAGNTDLSSRTEQQAAAIEQTAASMEQLTATVKQNADNAHHASKLAEDASGKASRGGQMVSGVVQTMGNISTSSKKISEITAVINSIAFQTNILALNAAVEAARAGEQGRGFAVVASEVRTLASRSAQAAKEIEGLIGASVSLIEQGSEEVIAAGSTMNEIVDAVKRVTDIMLDIAAASDEQSRGIVQVSQAISEMDRVTQQNASLVEEASAAARSLEEQAARLTQAVDAFRL 529
6 -93.700IDP01047 putative methyl-accepting chemotaxis protein STM3152 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  43  179..................................................................................................................................................................................................................................................................VMVDGKTYTIRILLITAVILGIAILIFTDRYLVAMMVKPLERIRQQFQRIAQG--DLSQPIEALGRNCVGRLVPLLRAMQDSLREAVSTIRAGSDNIWRGATEISTGNNDLSSRTEEQAAALEETAASMEQLTATVKMNAEHARQASQLADAASLTAGKGGELVSDVVETMNGISASSQQIAEITTVINSIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRNLASRSAGAAKEIEALIGESVRRVAQGAQLVQETGATMDAILRGVTEVTTIMKQIASASEEQSKGISQVGVAITQMDSVTQQNAALVEQVSAAAAALERQTEDLQRSVQQFRL 513
7 -91.400IDP02076 putative methyl-accepting chemotaxis protein [Salmonella typhimurium LT2] STM3216 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  39  179..................................................................................................................................................................................................................................................................VQVEGDFKTNRTLLITLALISIAAGCVMGWYIVRSITRPLDEAVRFAEAIADG--DLTRHITTDYKDETGVLLQALMAMKTRLLDIVQEVQNGSESISTAAAQIVAGNQDLAARTEEQASSVEETAASMEQITATVKNTADHTSEATKLSAGAASVVKNNGEMMNQVTQKMRVINDTANRMSDIINIIDSIAFQTNILALNAAVEAARAGEHGRGFAVVAGEVRQLAQKSASSASEIRNLIEDSTSQTQEGMHLVEKASALINGMVDNVEEMDVILREIGQASREQTDGISQINSAIGLIDAATQQNSCLVEESVAAAASLNEQALHLKELVNVFRV 513
8 -84.900IDP01957 putative methyl-accepting chemotaxis protein [Salmonella typhimurium LT2] STM1657 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  33  23..................................................................................................................................................................................................................................................................DTLQIAFLHDLPILITCNIIYLISALLLWWYMTCYLVVPINTVKKSIEEVAAG--NLSIHISEFGNNCAGRLIPGINSLSENISALVREIRSSSQTAMTLSEQLAARSLSLSVKTEQQSASLIQTAASIDEMAASTKNNADNTRMASIQADCATQCARKGGELMVRVTENMRSITDCASQMTEIISLIDGIAFQTNILALNAAVEAARAGDHGKGFSVVAGEVRNLAHRSAEAAKSIKALIDVTHDNVRQGAAIVQEAEKNMQEIVGGSGQLNVLMSEISTTTREQEKGINQITLALSDLESATHSNVLMVEALSASSDVLKAQVIELQTKTDKFRL 357
9 -54.100IDP01485 hemolysin secretion protein HylB VCA0220 [Vibrio cholerae O1 biovar El Tor str. N16961]  ali follow..  28  185..................................................................................................................................................................................................................................................................HASVESFEAGRTKQMVIIAAGLIISFITSLVIITNLRSRVAYLKDRMSSAA-ANLSLRTRLELDGNDELCDIGKSFNAFIDKVHHSIEEVAENSKELATMASSVSQRAHMTQSNCASQRDRTVQVATAIHELGATVSEIASNAAMAADVAKQATLHSGEGKKVVGEVQNRIQSLATQINGISSTLDTIRSISEQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLASRSAASTEEIQQVINKGRSQSDVVVEFSAKANQSLTEINSQIDQINDQNIQVATATEEQSTVVEDINRNVEDINQLTTETSHVADELSRASASLQRLSSQLDKLVGSFEL 548
10 -53.200IDP04179 methyl-accepting chemotaxis protein [Vibrio cholerae O1 biovar eltor str. N16961] VCA0068 [Vibrio cholerae O1 biovar El Tor str. N16961]  ali follow..  30  185..................................................................................................................................................................................................................................................................DESEHEHDSVMSQSTFALIGILLVAALSSWLLAGIIVTPIRQLQQTVREIAKG--NLLVKAQEEGNNEITLLARDVNATVTQLRQTVESLVRISTDVASASTELATVMTQASVNSDQEKQEVEQVASAVNQLQSTAQSVTDHAHSADGAAQQANQLASQSLRMFEESHRAVNQLKEQSERIGNVTEVIRSISEQTNLLALNAAIEAARAGESGRGFAVVADEVRMLAARTQTSTQEIQAIIESSLSLLEQNQSLAAKVSASLTEINHSISALGQINAQVATASEEQSQVTKDINRNLSNIYELVSQNVTGITQSAAASHELSDLAEQQHQQLQYFRV 547
11 -52.000IDP95280 methyl-accepting chemotaxis protein [Acinetobacter baumannii ATCC 17978] YP_001085820 [Acinetobacter baumannii ATCC 17978]  ali follow..  29  293.................................................................................................................................................................................................................................................................................................EYDRNQNAILRLLDEIADLADG--DLRSYATV-SEDFTGAIADSINFAIDQLRDLVSRIHETSQEVARYTQDTQSITNQLAEASEHQAQEIAGASTAMNEMAQSIDQVSANASESAEVAQRSVQIASNGAQVVNRSIEGMDTIRESSQEIGNIVSLINDIADQTNILALNAAIQASMAGEAGRGFAVVADEVQRLAERSASATKQIETLVEQTTTEVVRGANLAKDAGIALDEIQKVSGDLAKLIASISDAAKLQSASASHIATTMTVVQEITSQTTTATFDTARSVSELANMAESLRESVTDFKL 623
12 -51.500IDP91343 methyl-accepting chemotaxis protein [Vibrio vulnificus CMCP6] VV2_0072 [Vibrio vulnificus CMCP6]  ali follow..  25  174....................................................................................................................................................................................................................................................................................GLGIWSLLLLSVAISYSSTRRLESLSAEARKVFDN--PLMELVYNKKVDDISEIKLALKMRQSELNAVVGRIQDSNQQLIDSARNSSSNSDKASHNLKGQTHETEQVAAAITEMHSTANEIAQNAQSASDATDQAHSAASEGMITVQDTVKAIKQLAQHGKTIGDVLIIIQGVAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRKLAQRSHESTEEIQKVIGEGTHLAEQCVSSADSSGQKLQILLDQVTDISDRNNQIATAVEEMARVTEDMSSSVQSISDACSATNVLSSDTCHQCNALVKSLDSQGKLVSQFR. 517
13 -39.200IDP95064 methyl-accepting chemotaxis protein, partial [Campylobacter jejuni] AGM39603 [Campylobacter jejuni]  ali follow..  19  2..................................................................................................................................................................................................................................................................................................................................GSKINHSDLQKLEEENKNLTHKIEKFQSENLELKNKITSLEQAALESKLKTDLLNVLLTGVLKNITIIQGDMLENVNKAEVISSYSKTSLAEMDELNHIANSINASLRNITESVDEITNVINLIKDVSDQTNLLALNAAIEAARAGEHGRGFAVVADEVRKLAEKTQKATTEVEMNIEQVEKISIDSNAHIMSFSEKFTHLVNEAHSTNSNAVGIASEAFVSLAKLDHIAFKLNGYKEIFSKSGKQLADHTSC.................... 282
14 -34.100IDP01046 putative methyl-accepting chemotaxis protein STM3138 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  17  3...................................................................................................................................................................................................................................................................................................................................................KKVLGLRHWNNNVVKIPPPAAESGANASDVVVDTPEPYEKILMGISTIDIIRNAIIKSCEQLNIEKERINELNEQNDKARSSLKSLVEFITEINTSLTQINACIKEIQKIANQTNLIAINSAIEAARVGDAGRGFSVISKEVKNLSEDVKHSSKSVSTLTDNQQPVIDNITTNINQIVESIGIVIDKSLSMKSVMQYISTVQFLNIVKVDHVIWKMEVYKLLLNKDIN............................ 263
15 -28.300IDP91610 gene: ECs4554; EspB protein [Escherichia coli O157:H7 str. Sakai] BAB37977 [Escherichia coli O157:H7 str. Sakai]  ali follow..  11  19............................................................................................................................................................................................................................................................................................................TTGASSAVAASALSIDSSLLTDGKVDICKLMLEIQKLLGKMVTLLQDYQQKQLAQSYQIQQAVFESQNKAIEEKKAAAGILGSFAAMNNAAKGAGEIAEKASSASSKAAGAASEVANKASAMQKAMATTTKAASRASGVADDVAKASDFAEDLADAAEKTSRINKLLNSVDKLTNTTAFAVTSLAEGTKTLPTTISESVKSTHEVNEQRAKSLENFQGNLELYKQDVRRTQDDITTRLRDITSAVRDLLEVQNRMGQSGRLA................................. 311
16 -20.900IDP04191 sensor histidine kinase [Clostridium perfringens ATCC 13124] CPF_0554 [Clostridium perfringens ATCC 13124]  ali follow..  12  23...SIKNRLIASFSVGIIFCSSILGILLYKKATNALKNNAINYSENMLSIMSEDIYKNKEFLERASIELSMNEEIANNDYLSKKLSLLPNLAEVEIISKDYEVTYMQGFK-----YFKREDIERYADESENGLFWFS---ILNNEPHICIVTPVKQDNSIVGYVFMAIKSEVFASSFSLFNIGKGSEIFIIDDKNNIIISENNLNSNFILEETDLNKFLKDKGAKDTARSIVVNGENYVATYRKLKGFNWYIASMTPYDFINADIQSLRKEMTIIGLLFTLVVLIFSYFLYSSIKVPLYNLLNKMKRVSEG--DLKVLVNDTYEDEIGVISDNFDSMLKRVNELIEKTKL--QEVEKRDLEIRMLQAQINPH-------LFNTLNSLKWT-ALMNQDYTVSEGLSSLAELLRNTIIDKNELVT--------IREELENIKNYVVI-NSFDVQYEVFILQPIVENS---------------IHGIDENKENQKIIIKIMSEEENILIS-----IKDNGKGFNS------------KEKVKDNKLSGIGWNNVDERI........................................ 553
17 -20.200IDP92066 gene: GAPDH2; apicoplast glyceraldehyde-3-phosphate dehydrogenase 2 [Toxoplasma gondii] ABO93620 [Toxoplasma gondii]  ali follow..  11  187..........................................................................................................................................................................................................................................................................................................ERFEQEERRQRGGDGTCSESSDAAFAPEFSDLRDLFFGACDAT---------VSPDDLPSVPEALEKLAGLESDVQARGDQLDEKEKVVAEYLVAAQEAAVRHEEASRAFEDAKR--NKKENLAAAAEKAALEAAAEYADLTTAAQLVTEEAEQESAKA------LADAVAAGDLRFAINQKIVNEAGPEARGKVPRALLAPKHVRISDPAAGRVLKIFFHNNFAPFEDLPCAALHADAHLCRQHPRCVVQVEQSGDEVLQRCLLDEAYLALLTKTPDFCAAAPAEAETGLGNSAA. 469
18 -18.500IDP04495 sensory box sensor histidine kinase/response regulator [Vibrio cholerae O1 biovar eltor str. N16961] VC0622 [Vibrio cholerae O1 biovar El Tor str. N16961]  ali follow..  11  277..............................................................................................................................................DGKQYAWLGAPIIQQGYLHSYAMFRLPSNAITKLIAEGSSNPSMQTILVGQDHRSRTLTSAEIAVEKSKAVVDLA-LSGKRAVGTYTNTDGEQIIAAYAPINLKNIHWALVVELPEKEAFARVRQLEKLFVFAMLTAIVLVVIASHYLSNFITSPLLKLTWAAERVSAGDLD-EAMINTERKDEIGRLAVSFERMQRSIREKISLIKSQNKELESNLLIIRKQNDELQLANKLKDEFLATTSHELRTPLHGM------------IGIAEALISGANGPISAAHKYQLDIIISSGQRLATLVDLLDYHKMRYGALDIRLVLELSHHLLGKKTLRIVSEQPVWVSADPQRLEQVLYNLIGNAIKYTSEGK-QVVDTGQGIPA--EQLEHIFEPLIQAGHDASRYRQGAG-LGLSISRQLIELMHGTLYVSSQPMVGTTFS............... 725
19 -18.000IDP04241 sensor histidine kinase [Clostridium perfringens ATCC 13124] CPF_1112 [Clostridium perfringens ATCC 13124]  ali follow..  11  14...SIRKKLIISFSISVSIPIIVLGVYSFSESRKNLLIQTEKTMENNSLRIADEIDFKLKKEEGYAKYLAYNLNFRKVIEFWYFITSDDYIKEINIYTPNVSGEIGSFLKPSNFVE--GEEWYKKSEKSFKPFWSYEDGKLFITRSILD----TATNSKVIGVLRIELFMSIITEPLENMDFLDNG-IIIKDNSGNIVFKKLMKNSKINELVLENILN--------IKSGANLKEKEYLICENNIDASNWKVFYYLDKKKITEELIPIIGSTLLIVIFCLIVVVILINILSKALSRRILLLKDKAEDVSKG--NFNNPIFTEDTDEIGIVTNSFGHMTRDLNDMINKVYK--IELEKKATELKALQAMINPH-------LYNSLSTIKWK-AIREGNDDISDITGYLAKFYRTSLNNGQDITD--------VKSEIDNIKSYIEI-YSFDVEYRIFILQPIVENA---------------KHGIDCNQGKERGKIIVEFQEDEDSL-----KIYNSSNNNDI-----NSIEEMLNK-----PGKGYGIYNVKERI........................................ 540
20 -18.000IDP04347 sensor histidine kinase [Clostridium perfringens ATCC 13124] CPF_2345 [Clostridium perfringens ATCC 13124]  ali follow..  11  7...NLYKRLFITYTIVILSVVSILCIYFLSKTSEEIKRNNLYLNDKILQDVNETLEYNSSTSRRIMNMLYEDDFRLNDVIKYLNSDLVD-KSSFQLNNFLKSISFISYSRNEISVFNRKGEIKTYPFNSNELLDKKDIEYAIYNKNEISIINEIRDSLKPEGMLMTTYDVGVISDVIKKYK-DTNSEVLILNKEGMVLYDSENKYDYEYYPYFDKL----------KVGRHEILLEDSYYVDILPDNNGLMSVVRIKVSNATKVPLLFKVSAFLVSLFLFIIAECVLYIKFKNLSSRMDSLVLAMEKVEKGDIDVHIPLS-KDRDEITFIADNFNKMCEKLNDHIRKS---------------------------YLAELRQREAEIVALQNQINPH-------NTLESIRMKAICNGDKEVGKMLYSLAFLFRSQVKGNLIVSIDQEIKYCNKYL----ELFKFRYDEKFKFKIECEEDLYDKGIVKFTLQPLIENYFVHGIRLERDDNELKIYIYKHLEDIVVEVEKLDDINRRIRECDHSGKSGMLNVHERI........................................ 546
21 -16.900IDP04165 sensor histidine kinase [Vibrio cholerae O1 biovar eltor str. N16961] VC1521 [Vibrio cholerae O1 biovar El Tor str. N16961]  ali follow..  10  15FQTTVRYRLWILTSAPIFLTLLALIAITIYWSLHYTWNSALIDVSERLGVAQNSVTLLQQKQANHVRAFAESYDLSTLPRWVQNQKNRYGLDFLSFERVDSLEQKFRYLDLTKRESFFDVLSADELEKLDPDLAKQAQI-IETRGLVSRTVIPVRNFGEIIGFLDGGLLLNNSTTLVDQIRLIYPSHQDQLRPTGTLTLFLDDLRVSTNVPLDSNIHAGRAIGTRVSSELAYVYDAWYITAYEPIRDQY-MLYTGYLMWPFLKAYVTNILEVGIITLFLLVISGLFVYRGSRDLFRPIERIHRVVKMVQLGKNQRIGQIGLDDKHELAQLAKQFDNMLDQLQQRNEEIVQAAHELEAKVQSRTASLQEKTAQLEHHIALLNQTRNKLEKLAALGELTAGIAHEINNILGNTELIRFELGADASRVEEEIDAILLQIERIRNITRSLLQYS-EITWQHVNPIIDESGSKKRDIEFVLELKAHNSVEVNRHQLLQILVNLQMNAIHAMNGKGRIIEDQGCGIKP--ENLKRIFD-------TTKREGTGL---GLSVSQ--SLLSQSGGEIKVQSELGVG------------STFSI 660
22 -16.000IDP90961 GGDEF family protein VP0117 [Vibrio parahaemolyticus]  ali follow..  12  9...TLRTAVLIPFVMIFLLAIGVIVYVQKQSYEEVVTDISDKQLSVLTESVYDHLNSYLRKPFTAVMTLAHNVSYHNLYHPHDTRDVQAYLLSAFQNLYRSIPQLNDIRTVITPYDPRTRPWYQPVAKDEKPMWSKIYTNADERQITLSAMTPVYEHQEFAGVLVTDIRINTFNEFLRVIKKNTKASVFIMDQEHRLVAHSGPGSVVSWGTKFSDKGQRLFASESADPIIKISASRSRITPYYDPNGLTWFIGTSISESDLLGLLPKSQEKSWIVGIVVSLFGIGFSWVIFERVTRPINATADAAQHLANGDWDSSMPQP-GRVYETTVLAKAFNEMASNLKASFKALRDQLDSLTRLYSRQGLIEICENKPNLCHGSLFLLGINKFRDINDSVGHHNGDAERLKQQFPDNTMLARIGGDEFALFMPDMDKDEDIRLTERRLQQLFAGIVQNMPLWLRNASIALSYAKQDPLTICYYSPELASASKFRTQLLTKMQTGIDKR--PIAEESGMIKAIGQILLQACRDTYKAIELHVNISVNQLSCPAFVDTVTRVLDVTKEITE--SRIIDSAPTTLENMMKRDMGIGIAIDDF.. 752
23 -14.000IDP02181 two-component sensor/regulator [Yersinia pestis CO92] YPO0256 [Yersinia pestis CO92]  ali follow..  13  5..SSLVTRLTLLMGVTLTVIWLILIATTAFFSYENTRQILINELTHMASMRADLSNHQFEGAERDAASLISRRESLQSTSPLPEISIKHYYLDSFIIKQKEGIVLFPPQKSSSDYRRKDLLLLPKFPTHNNIYWGAPTYTPQG-----GWHVSVAVCDKVGTLAGFALKLNDLIAYNHPVE--QRDINLLLDKNGELLPISQQATSSNQLHEILNQL------KNSKLHDGWQQTPDYLVLRTQLKGPGWQQLVIYPRMGFAWEAKPALYQLPFALAILLLLTSVLSLLLRYYLAIPLWNFINIIGATGPQ--AMEPRLPINRIDELGHIARAYNNLLDTLNEQYDTLRRKSDHLTTISHEIRTGAVELLQNTPGQMRLAETAHQCSLSLLAIINNLLDFSRESGQMTLSLEKTALL--PLLDQAMLTIKSLALSTFISANIPLELELDTLRLRQILVNLLGNAVKFTPQGRGCGIDVQHQQTIFQPFMQTSDHE------------QGTGL----GLAIA------DNLAKMMGGHLTVFSEPGQG................................................ 605
24 -13.600IDP04672 sensor histidine kinase [Bacillus anthracis str. `Ames Ancestor`] GBAA1482 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  9  265..........................................................................................................................................................................................................................................................YAFAIASLQPVNEAMLVLKDYYVYALIIVFLVIILLSFYYSKIIVKPLIKINRVTKKMANF--DFSEKLPVTADDEIGGLSGSINTLSVNLKDRIDRLNVANTKLQQDIERERQLEKTRKEFISGVSHELKTPLSVIRSFAEGIKDGV--SKDTTYYTDVILEETENMNRLIVEMLE-LAKLESGTYKLDSIGELIQQVYTKLLFSMEEKHLQVNIDVNSS---IFVKANRSRIEQ--------VVNLLSNAIRYTPEGEKIIENTGNPIPE--ESLEKIWDRFYRLDASRSRHTGGTG-LGLSIVKNILDLHHAEYGVYNTTNSVV.................. 591
25 -13.500IDP04691 sensory box histidine kinase [Bacillus anthracis str. `Ames Ancestor`] GBAA5067 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  9  289..........................................................................................................................................................................................................................................................YIYAMASLQPVDEAVQMVQDYYIYIIAFVVVLIFLASFYYSKQIAKPLLKINDTTKKIAHL--DFTEQIPITSKDEIGDLSKNINTLSNKLNSHIGQLEQDIEKE----RKLEKTRKEFISGVSHE---LKTPLSIMKSCISILKDGVAEHKKEYYFQAMERE-VDKMDTLILDMLE-LAKFESGTYKMKYIDTVMEAICEHLSVEIEKKELRVHKHIGP----FEVVANQGRIEQ--------IVNFITNAIRYTPNKEDIIENKGTHIEE--EQLDKIWDRFYRVDAARQRSQGGTG-LGLAISKNILELHDAEYGAENTEDGVLYLPKKA............ 617
26 -13.500IDP04694 gene: yycG; sensory box histidine kinase YycG [Bacillus anthracis str. `Ames Ancestor`] GBAA5714 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  13  6FFQSIHLKFVLIYMLLILIAMQVIGVYFVRELEKSLVQGFRDSLTQQTNLLSYNLKQEFKKSYTKAETESTDETIKTSIRKFASDRKKDIQEVSVF-DANRKLLAISDESKQNKVNRTSTDIAVQRVLVQKKPEVKIEKDGRTGHRVQVMITPIMDDKDALGAIYVVASMEDVYKQMKDIN----------------------------------------------------------------------------------------QIFATGTVIALLVTAVLGILLAQTITRPISDMRRQAIEMAKG--NYSRKVKVHSHDEIGQLALSFNNLSKKLQQARSSTESERRKLSSVLSHMTDG---IATDRKGDIILLNDPAEKMLNVSTALDQSVLEVLGIQEEFTLDHLYEEPDSVLLDFSTRSFSVIQKETGKANGLIAVLYDVT------------EQERIERERREFANVSHELRTPLTTMRSYLEALTDGAWQDPNIAPQFLTVIQEETERMIRLVNALLQLSKLDSTEHRLMKEWVDFTDFFNNIIDRFEMSKEQNVSFKRSFSKKSRFIDMDTDKITQVL..... 503
27 -13.000IDP04331 sensor histidine kinase [Clostridium perfringens ATCC 13124] CPF_2181 [Clostridium perfringens ATCC 13124]  ali follow..  7  159..........................................................................................................................................................................................................................................................IIIAITSFQAIEEASALIKDFYKYIILIVIVIGLILSYVFSNLISKPLVKLNKSAKKMSAM--DFSEKCDIEREDEIGNLAKTLNFLSKNLSNALDDLKIKNKKLEEDIEKERELEKLRKDFIAGASHELKTPIGIISGYAEGIKDGIVDHKDQGVYLDIIIDEAEKMNKLVMDMLE-LSKLEAGKIDLHSLTELTEEVLVKNSVDINKNNLTVVKNYSPTEDLYVQGDDFK--------IEQVLTNFVTNAIKYSEPNNQIIENTGAHIPD--SDINKIWTQFYRGDTSRNRGSRSTG-LGLSIVKNLLQAHESEFGVMNTENGVK.................. 490
28 -13.000IDP04182 sensor histidine kinase [Vibrio cholerae O1 biovar eltor str. N16961] VCA0238 [Vibrio cholerae O1 biovar El Tor str. N16961]  ali follow..  13  187...........................................................................................................................................................................................................................................................QRTSRYEEAALDALSNVRSVITSLAVFGMVSGALLGVWLLRTLSKPLAELVKSTTALEQG--RLDHRISISGPDELKTLARHFNYMAQSLEQAQQKERMSRQLI---EREVADRTQELAQALQT----LEKAKHQQKEFFANVSH--ELRSPATAILGEAQITLRSRHNSDDEYRQTLLRISESAEQLAFRIE---------DLLML-IRHDERLFHPALTELLLVVRQASLLTHAQQKLLMVIRILVDNALRYDPTQQPILVDQGIGIAE--ADLSVIFERYFRAENGKRYRPDGLG-IGLTLAQSIVKQLDGEIRIESVLEQGTTV................ 533
29 -12.400IDP04484 gene: barA; two-component regulatory protein [Yersinia pestis CO92] YPO3381 [Yersinia pestis CO92]  ali follow..  13  159...........................................................................................................................................................................................................................................................IAIDLDLQSVRLKQYKEIFISTLLLLFCMCVAILFAYRLMRDVTGPIRNMVNTVDRIRRG--QLDSRVEGHMLGELDILKNGINSMAMSLAAYHEEMQQNIDDLRETLEQMEIQNVELGLAKKRAQEASRIKSEFLANMSHELRTPLNGVIGFTRQTLKT--------SLTPTQTDYLQTIQRSANNLLCIINVLDFSKLEADKLILEIILLAHTAHEKGLELTLINNDVDQVLGDAMRLQQIVTNLLGNAIKFTEEG------------NIDILVVVKAIASQQVTLMVEIHDTGIGISESQQAQLQAFRQADASTSRRHGGTGLGLV--TERLVKEMG.... 496
30 -12.400IDP04543 sensor histidine kinase/response regulator [Vibrio cholerae O1 biovar El Tor str. N16961] VC2453 [Vibrio cholerae O1 biovar El Tor str. N16961]  ali follow..  16  158...........................................................................................................................................................................................................................................................IAIELDLSSLRLQQYQEIFSAGLVLVIGILLSGVFASRLMYDVTRPITHMKNMVDRIRRG--HLDVRIEGKMHGELDTLKKGINAMAVSLSEYHVEMQHSIDQLRETLEQLEIQNVELDIAKKRAQEAARVKSEFLANMSHELRTPLNGVIGFTRQMLKT--------QLTNSQADYLQTIEKSANNLLTIINILD------------SKLEAGKLALENIPFEVLEEVVNLQATSAHEKGLEITLKIDPKIPRGVVGDPLTNLVGNSIKNIDVSVEMRALRDDVIDLQFMVRDTGIGISERQQAQLQAFSQADASISRRYGGTGLGLV--TQKLVSHMG.... 495
31 -12.200IDP95472 sensor histidine kinase [Listeria monocytogenes 10403S] YP_005962624 [Listeria monocytogenes 10403S]  ali follow..  13  1MKFKYAYQLFFTQFIILLIACIMIGVLVSHSLKDYFYQSQVDDLTSYGQTISRDIRYSPQDATMQVLNTYQRILDVK--------------IHYTIKNANDETIYPTQMNQPLPKDFSISADDKKKLESGETVSKK--IDNRFNKEMTIVYVPIMNGDKFVGSIVLNSPISGTEQVIGTIN----------------------------------------------------------------------------------------RYMFYTILLSITVALILSAILSKLQVNRINKLRAATKDVIQG--NYNARLKENNFDEIGALAIDFNKMTQTLETSQEEIERQEKRIADVSHEMRTPLTTISGLTE----GLVNDIIPKSETDRCIALIDTEARRLTKLVNENLDYEKIRSNKIKLQKTRFN-----KEFLELIKEQLDYVASEKGNITVAIDKDMAIYADYDRLTQVFINIVKNSVQFTENGQITLTGTQDYKESVLT-----ITDTGIGMNT--EELEQIWERFYKADMSRTNTAFGESGIGLSIVK--QLIEYHDGSITVTSEPNKG................. 461
32 -12.100IDP04012 gene: virJ; sensor histidine kinase [Clostridium perfringens ATCC 13124] CPF_2355 [Clostridium perfringens ATCC 13124]  ali follow..  11  71..........................................................................................................................................................................RYIPKISNDISEQGKCQIDVFNEDLEKEYSYYLDDFSFDYEKDGGYDVLKEANKNKAALNIYRDENAVKAYLA--ESFLGNILLSKDYSKEYLELRDLMSNIKFIVSITFLLILIFTYFLFERIINPLNYIKNSFKRIGDG--DFKINLKVNSKDEIGDLACGVNKMANKIEEQIEKINEEKEKVLTLE----------KTRTEFFNNITHELKTPLTNISGYAQIMSEEDFHDNDFRKFALERINKESKRMHELIVSLIEISKNKSENVNLKTLIEDLCEDFKVKGDKQGICISNNLED----IEFMCREDEIRR--------IINLLDNAIKYSIKGSEIIENLSDEISS--EGVEKIFEPFYRENTKKSRELGGNG-LGLYICS--ELVKKYGGDISFNYSNGKV................. 475
33 -12.100IDP04438 gene: cpxA; two component sensor kinase [Yersinia pestis CO92] YPO0073 [Yersinia pestis CO92]  ali follow..  12  143..........................................................................................................................................................................................................................................................LYLIRPANSPQSDFINLMFDRPLLLLIATMLISAPLLLWLAWSLAKPARKLKNAADDVARG--NLKQHPELSGPQEFLATGASFNQMISSLDRMVVAQQR----ISDISHELRTLATALMRRRHGEGKELERIEMEAQRLDSMINDLLVLSR--------------------------SQHKNELHREPIKADELWSDVLENAQFEAEQMGKTLVVTAPPGP--WPLFCNPAALDS--------LENIVRNALRYSHHHIAVVDDDGPGVSP--EDREQIFRPFYRTDEARDRASGGTG-LGLAIVE--TAVSQHRGWVKAEDSPLGGLR............... 446
34 -11.900IDP04428 gene: phoR; sensory box histidine kinase PhoR [Bacillus anthracis str. `Ames Ancestor`] GBAA4832 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  10  63..........................................................................................................................................................................LKNPYVFEKLEEKIQASIAFVDEKKKVQY--SGGEQSAFSQGIMKELSSETKKQRNKVITKEADQNNEFYHAVFVQDVT-YILVKSTIEPLKDVHQKTWGLLIIGFVIACLVVVFLGMKITGQYIRPIESVTKVAIELAKG--NYKARAYESHSDETGMLSKAINILARNLQEMTLEQEMQQDRLHTLIENMGSG---ILIDSRGYINLVNRSYKETFHVTDYLDRLYYESFHHTEIIELVEEIFMTEVKVRKQML-YGAPIIGTNHEWKGIVLVFHDI---TELKKL----EQMR-----KDFANVSHELKTPITSIKGFSETLLDGAMDNKKFCEHFLHIILKESERMQGLIEDLLDLSKIEQQGFKLSMGTVDMKGLLEDIHMVLDNKAGEKEISLQVNTLKRVSVIGDPSRLQQIF..... 481
35 -11.800IDP04673 gene: resE; sensor histidine kinase ResE [Bacillus anthracis str. `Ames Ancestor`] GBAA1498 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  12  155..........................................................................................................................................................................................................................................................AVFVYESLQVPIQGMERTTDFIFLSAGIAIILTTFFAFFLSTRITAPLRKMREVAFEVSRG--KFDAKAPMVSQDEIGELATALNQMGKQLKFNMNALQQEKEQLASILSSMADG---ITLNQEGEVVVINPPAEHFLQVWQEEKEIELSKKLPSELVELFHLVVESEQQQVVGINLQKGNYVVLMTPLYN--TKIRGA-----VAVLRDMTEERRLEKMRQDFANVSHELRTPMVMLQGYSEAILDDIVQTKEEINEFVQIIYDESVRLGKLVNELLDLARMESGNVELHIGEVDIHPFVEKIGRKFQIAKDKEVALTVDFKDSIEQYPFDADRMEQVL..... 486
36 -11.500IDP01908 gene: ssrA; sensor kinase [Salmonella typhimurium LT2] STM1392 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  15  263..............................................................................................................................................................................................................................................LILRTTLHGPGWSLVTLYPYGNLHNRIKIILQQIPFTLTALVLMTSAFCWLLHRSLAKPLWRFVDVINKTATA--PLSTRLPAQRLDELDSIAGAFNQLLDTL--------------------------------QVQYDNLENKVAERTQALNEAKKRAERANKRKSLTVISHELRTPMNGVLGEQQGLADTARNCTLSLLAIINLLDFSRIESGHFTLHMQTIQGPAQSKKLSLRTVGQHVPLYFHTDSIRLRQI-NLLGNAVKFTETGG-LVSDSGKGIEI--QQQSQIFTAFYQADTNSQGTGIGLT-IASSLAKM-----MGGNLTLKSVPGVGT................. 604
37 -11.400IDP04667 sensor histidine kinase [Bacillus anthracis str. `Ames Ancestor`] GBAA1313 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  12  44.........................................................................................................................................................VMEGKRLAAQYDKSEGISTFEEKVRAFDQISSSDVLFVSNPRDLSACLPFDVHHHSLISEGDRQALLDGKTVTKIGYEEHFERNIMGVVIPVLENK-IVYSYIPLKSIKDLIYDMGLILAPLALAITLLTIWIGRKIIIAITRPLSQMERVANHLATG--DFSERITISSEDEIGRLGKAFNKMANSLETE----VKRKEFLANVSHELRTPLSYIKGYSE----AILDGVAKGPQQEKVTQLIHKEADRMQRLVHDLLDLAQLEGEHFPLQKQPIV-----SQLIEDVLDTYEIKFIEKKIISTNLNPEIIVMIDEDRMQQVLHNVLDN-AIRYTNQNGDIMITLRQIDDYCE----SIKDTGIGIDT--EHLENLGERFYRVDKARSRQHGGTG-LGLAIVR--QIVHIHDGQWQIESEKGNG................. 450
38 -11.200IDP06113 histidine kinase sensor protein [Helicobacter pylori J99] NP_222872 [Helicobacter pylori J99]  ali follow..  9  110..........................................................................................................................................................................................................................................................ILLKKDEHFVLYKDLHSVSYRNYFLAITVGLLLILFLFLFVLQSLLPLRELRSQVKRFAQG--DKSVSCKSKQKDEIGDLANEFDNCIQKINAMNESRVL----LRSIMHELRTPITKGKILSSKEELSCKRFSSIFDHLNMLI----EQFARIEQLASKNYGSNKEKFLMSDLIDKIEKMLLIDEDKKSPIHVSSSNYIIEADFELFNMIDNAIKYSDDKQVFLDFIGNNLVVSNKSKPLKEDFEKYLQSSNPSQAHGFGL----GMYI------IKNALEAMGLNLSYHYSNGRICFTIHDCVFNSFYDLEADNEELPPPRKFERGEGNEGNRKSQL...... 440
39 -11.200IDP04132 putative two-component system sensor kinase [Yersinia pestis CO92] YPO2997 [Yersinia pestis CO92]  ali follow..  12  156...................................................................................................................................................................................................................................................................................IWMGVLGGLFFSTLLAWNLTRPMRQLRVGFERVAQG--DLSVRLLRRRHDELTEVARDFDSMAERLQALVSAREQ----LHDVSHELRSPLARLQLAIGLAHQNPDNVDNALQRIEHESERLDKMIGELLALSRAENHSL---------------ADDDEYFDLQELVVVVNDARYEAQLPGVEIQLEVAAQSE-----YTVKGNAELMRR--------IENIVRNALRFSASGQQVKVTLSALDKRYQIQVNKLSSIFDPFVRVKSAMSGKGYGLGLAITH--KVILAHGGQVEARNGEQGGLV............... 439
40 -10.900IDP01736 sensor histidine kinase [Bacillus anthracis str. `Ames Ancestor`] GBAA5503 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  12  68..........................................................................................................................................................................PNSLLIASYLAKRMDVRVQMIGKNGDVVADTQKGALLHRNIDIE-----SSLKGKKSYVFEEGDPAPILLFSSPVYYGN-SVRFINELTGEKEVLTNVGWTFLMTSLCLVAAGIFFAIRLAKSLHKPIDQLRQMAHRLANG--DYKSKIELNEYVEIAQLSASFNAMADGIELHIKQLKEEKEKLDRITHELKTPLTAIIGYVD-----LIPKLKAKEDVKESLRYVAVESERLLSLVEELLKSSKYGTSTFEISPTVVN-----KELAEEAVSIVKPRLQKFEIEVINELTDVHVVADFDKTKQIFLNVLDNAIKYSDATQIRMNVIVNEREAKVF-----VHDDGIGIDE-----GVLAEWNESPEGKILPSSYGHG-YGLYICQEIMDKQGGSMRIESSEEIGTTI................ 456
41 -10.900IDP04352 sensor histidine kinase [Bacillus anthracis str. `Ames Ancestor`] GBAA0584 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  11  98................................................................................................................................................................................ESESISNSDIAIIITDNNGKIISTSEPVTKAMQ-KQLTCKTEPIPKDGLIVEKNWKKSKFITTVSPIHTTEFQGKLYMLLKTSFLENMLLKLMKQFLIISVLTIILTTISVFIFSRVITEPLIKMKRATEKMSKL--NKPIQLGIKRNDELGSLAKTIEDLSSELTYM----KERGEFLASVAHELLTPLTYMKGYAK----VAKRDSLTKEEREEYLQIIEDETDSVTDLVQDLFMLVQLEQHQFVIKKQKVL-----RPFLERMVEKTKTTLTNKQMLHVYCKDDLEVCIDERRMEQVMLNLLHN-AYQHSLENTTITIRVLAETNSFT----SVQDEGEGIPE--GDIPHIFDRFYRVDKSRTRATGGKG-IGLAVAK--EIVELHNGSILVTSKLDVG................. 477
42 -10.800IDP04189 sensor histidine kinase [Clostridium perfringens ATCC 13124] CPF_0225 [Clostridium perfringens ATCC 13124]  ali follow..  13  80..........................................................................................................................................................................DNAPFIASTLSEKYNVRIQIISNSAQIIYDSSSDEVSLFGSDIN-----ESLDGQTAYIVEKIDNVPTLFLSSPIFYKG-AIRLILINTEAYEILRNTLTIFIISGLIAIVIAIFLINTFAKELVSPLMILKQKSKNISEG--KFKEELHITSGDEVEDLANTFNIMSENLDKYINEIKSAKLHFDNVSHEFKTGFSEIKEKIVQSSALIEKEGKRLLNLVEEILLLAKSNKNTFEIEYTYIDVK----SLIEDCLKILK-IYGDHDKTKQVF---------INII--DNAIKYSGCE--------------TLSISTKRSPNKMEVIIEDDGTGFIIKDEYVNPKGNGLGKICKDIMQSQN--YGFNIESELDVGTKVTLSFSIGKNNEIKEEDF............................. 474
43 -10.700IDP04515 putative sensor histidine kinase [Clostridium perfringens ATCC 13124] CPF_2673 [Clostridium perfringens ATCC 13124]  ali follow..  9  276................................................................................................................................................................................................................................................................................NRYLWIIPIVLVIHFIVKFIRKYDGLDTVIKGIEKVKKG--DTDIEIKDNDDRQIRELADDVNDLRLGYKELVEE-KLKTELISNVSHDLKTNYVNILQLNNIKEEERKEYIEILDKKSQTLKKLIDDLFEVSKMSSGKVELFKYNIDIIQLVYQCIAEVEDVYSE--------KEIEFKING-------------------CMVKIDPQRM-------SRVFQNLTTNALKYSLEKTRVYVEIKDLENYVEISFKNISSYAGDESRNSTIEGSGLGAIAKTIVELHN................................... 555
44 -10.600IDP04247 sensor histidine kinase [Clostridium perfringens ATCC 13124] CPF_1402 [Clostridium perfringens ATCC 13124]  ali follow..  10  69..........................................................................................................................................................................DYNSIGNQDYVTEHGGWIEIIDKDLNIIETIGDQKVKRDNYSSEEFSKILVDEMHGVNIDEDYLSYTGYSKEGRF-----NFGKMFTRNPKIGFKIFVYIMISLYIFIFTMSLILYSKLTSKTFTKPLDKLMNGVRKLSLG--DYSTRINIEKNNEFEELGEAFNNMASKIEEEKKLKEKSEKLVRNIAHDLKTPLSSIIGYSNIIKNNPDIEKESLHKYISVIENNGE---RANEMIMELFEFY--------TLQSSEFILHKKYQDLSEFLNLIADYIYLLEEKDFDFDFEISED-------LYLEFDNKRLER--------IGNLIINSVKYNKKGTKFVSDDGIGLSE--EIKKHIFNPFVREEKSRNSKKGGSG-LGLTISK--EIVEKHGGTIYLSDGPLKGCN............... 470
45 -10.600IDP04662 sensor histidine kinase [Bacillus anthracis str. `Ames Ancestor`] GBAA0650 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  11  43.........................................................................................................................................................LLKRGNSHRDVLEKYYDEQTISHVALMESEAETTVVITNTNKEVLAKSNKINTTIKNHISSMQTRTNHDGAIIENHWKTSNYICTVSPIIVAGKHEGYVYMFLGTESIEKLVNGLTKQFIIAGAITFLLTVITIFLLSRLLTKPLLHMKHATEKMSKG--DLSVSLTTTRNDEIGELSSSIQTLANDLHYM----TERSEFLASVAHELRTPLTYVRGYAD----IALKETTSPEQRLRYLSIIKDESDYITNLVQDLFSLAQMEQHNFSIQVKEVH-----HTFLTRISEKVNAMYKERYIVSFSCPPTLLVNLDEQRFEQVVVNILNN-AYRHSKEHSQIHISVIEENKRIS----TMEDEGEGIPP--EDLPHIFERFYRVDKARSRATGGTG-LGLSIVK--EIVELHGGNITVTSEVDHG................. 446
46 -10.500IDP04430 sensor histidine kinase [Bacillus anthracis str. `Ames Ancestor`] GBAA4921 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  12  152..........................................................................................................................................................................................................................................................SIFVLKKQSSFVDLTQKLFPILVSLLLLAILLIGLLSYLVSRSVIKPIFVLKDATGKIKEG--NLDFHIPVTSHDEIGQLNQGFEEMRKKLKESIEMQTQYEENISNISHDLKTPITSIIGYVEGIKDGVANTPEKMDKYLTTIHTKARHMDTLIDELFLFSKLDLNRVPFQFETVELNMFMQELIEEMQMDLS--EGIEVNLQLHASPLYVTA----DCEKINRVISNLIHNSVKYMDKEEKKITVTVSSDNNKVI----KVMDNGSGIES--DTLPYIFERFYRAEQSRNSSTGGSG-LGLAIAK--QIIEEHGGNIWAESELGEGTS............... 471
47 -10.500IDP02394 gene: phoQ; sensor protein PhoQ [Yersinia pestis CO92] YPO1633 [Yersinia pestis CO92]  ali follow..  10  171..........................................................................................................................................................................................................................................................TIVVVDTIPQELQRTDLVWNWFSYVLLANLLLVIPLLWLAAYWSLRPIKALASQISQLEKGERE---QLDENPPRELQSLVRNLNILLMNERQRYTKYRTTLADLTHSKTPLAVLQTTLRSLRTGKQTTIEEVEPIMLEQISRISQQIGYYLHRASMRSEHNVLGRE-PALLDSLYSALNKVYQRKNDFMEVMG---------NVL--NAEVTTLHSEDDGPG--IPENKRQLIFQRTLRPGQGLGLSIAAEIIEQYQGKISITESGARMM.......................................................................... 472
48 -10.400IDP04397 sensor histidine kinase [Bacillus anthracis str. `Ames Ancestor`] GBAA3230 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  11  133..........................................................................................................................................................................................................................................................WVRGIMTMSRLSSTMNTLIVLTLISFPLLILIAAVGGYFITQRAFRPVQQMSDSASKIGDGK-DLSKRINLKGKDEMYHLAQTFDKMFERLETSFESEKQ----TSDASHELRTPTSVIISQCE-----ALSQRNNPKEMEESLEVILKQSRKMSALISQLLLLARADQGNDNTF----------QFECINMSELTEIVVEELSLMVQEASIDITTHIEED---LFIKADQTLMMR--------LMNLLTNAIAYSKANGTVVSDNGIGISE--QHITKIWDRFYRVDAARTSSNIGNTGLGLSMVKWIVELHGGEITVESGLGEGSTFT............... 448
49 -10.400IDP04104 gene: rstB; two-component regulatory system, sensor kinase protein [Yersinia pestis CO92] YPO2309 [Yersinia pestis CO92]  ali follow..  16  130................................................................................................................................................................................................................................................................................LALLILIGLSLALPVFLWMRPHWKDLLKLENAAQRLGSG--HLDERTHFDPTSSLSRLGVAFNQMADNINTLIVSIDGIAHELRTPLVRLRYRLAMSDNLTESEQQALHHDIGQLEALIDELLTYARLDRPQVSLNLEPIDLP----AWLTTKIMDIRSIHQERE------------------IELDIPHRGDFGAVDLRLMERVLDNLVNNALRYSHQRLRIGLWFDGDNACLQ-----VEDDGPGIPP--EERTRIFEPFVRLDPSRDRATGGCG-LGLAIVHSIALAYQGSISVNTSPLGGASFR............... 409
50 -10.300IDP04358 gene: creC; putative histidine kinase sensor [Yersinia pestis CO92] YPO0895 [Yersinia pestis CO92]  ali follow..  11  2...KIGVRLLLGYFLIVAIAGYFVIRIFLQEVKPGVRRATEGTLVDTATLLAQFARQDILQNKVADGQLAQAFSSLNLRPIGANIEGIRKDRNVYLTDTDGQV-IFDSSGRALGQDYSRWNDVWLTLRGEYGARSSRTDPDDAESSVMYVAAPVIVENRIVGVLSIGKPNLSMVPVIKRSE----------------------------------------------------------------------------------------RKILFAGGLLLGIALLIGLGFVWWINRAIGKLVDYAERVAEGQA---VALPAMGSSELNDLALALESMRLKLDGK----AYIEQYVHTLTHE------------------LKSPLAAISGAAELLRESPPPETAQRFLINIEQQSAR-----IQQLVDKMLVQARLESRVDEISHILKQSFSAKEAQAVSRGVTLRLKSVDN---AMLIGDGLLLSQ--------LNNLIDNALDFTPAGGEIVEDSGSGIPG--YAQEKIFDRFYSLPRANSVKSTGLG-----LNFVREVAAIHQGSICLENRLPQG................. 463
51 -10.300IDP04007 sensor histidine kinase [Vibrio cholerae O1 biovar eltor str. N16961] VC1319 [Vibrio cholerae O1 biovar El Tor str. N16961]  ali follow..  11  132........................................................................................................................................................................................................................................................................YQAIDRADNLLFVFMLGGFALYCMFLIWFLSRRLRELERVTHDFANG--NLQARASTKSSKSVGKLNHSFNMMADKISHLILSNKALTNAI---AHDLRT-ESQLNAKQQQQVASIIEDTEEMETMVDELLYYAKLEHPESDIQSQYLEVN----QWLADFIDEQSHLDADPQLLTRALVNLNAEKYAGDRLLIEASTVDAKL-DNGPG--IEEQHWPHIFDA-----------TDSSRNKAQSGFGL----GLAI------VKQIMARHQGEVTLTKSPLGGA............................................... 420
52 -10.100IDP04542 putative two-component system sensor protein [Yersinia pestis CO92] YPO2000 [Yersinia pestis CO92]  ali follow..  11  145..........................................................................................................................................................................................................................................................RYVVAIDSTPYMGTLNEFTRTLIVITAIGVLFVALLGFVIARIGMRPVNKLSEQAQHLAPG--NHGQRLDTLTPDELQKLAVAFNGVLERQEIAWRQLESFNADV---AHELRTPLTNLMGQTQLGLSR----KRETHELEDLLESNLEELERMTSIVNDMLFLSHAQAGEHATQLTDV-----------SLREETYKTTEYVEPSFAEKNLSIHVEGD-----ITARIDRRLFHR--------LANLLENSARHAVTGTTVVANIGAPIAA--EHLNRLFERFYRVDSSRARSDTHHG-LGLSIVR--AVAIMHRGDVFASSQNGIN................. 450
53 -10.100IDP04158 sensor histidine kinase [Vibrio cholerae O1 biovar eltor str. N16961] VC1088 [Vibrio cholerae O1 biovar El Tor str. N16961]  ali follow..  14  132.........................................................................................................................................................................................................................................................GTVFIGFDLSYLEQQLAHARKWTLLIVLGEMGLVALFSYLLGNALTRRLTELKTATDQITFGNREVL--LEIQGHDEISRVAHSFQQMVQSLRHSEATMRDYQHQLEQWNLELED---KVNQRTETLLAKNQQLEEMNTKLTLMKDKLVETEKMIS-IGTLAAGFAHEINNPNGALKSHLQLLQQDFNQLKVGFEQID------ILLSGSDFHGKFTQTKNALYLEESFSGIEESLRDALHCVDRIKTIV-DKVQRCQAEPALHDSSWVSPLSLVEQAIQICGLREWVVWK--EQTLYPPLIYCYSNDFVTA------LSAILNNAYQAYASDDPMIRIELSL... 453
54 -10.000IDP04659 sensor histidine kinase [Bacillus anthracis str. `Ames Ancestor`] GBAA0272 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  9  96..........................................................................................................................................................................MIEMENQNLERGSRALKILVTDESGKVLYKTKQAQEEQIDLHNTIRNAASFAINYSNGRDVFENTRKEFIAFSPITIED--NLYMFVSGIPDGVVMYDTQEGPFPFLIGVLVFIFSFFYITKRKMKQIEAMAEGVKEIEKG--NLAYRIEKKGEDEIASLTENINNMAEELMNNIEKERKLNELITNVSHDLRTPLTSIMGYLRLLRDSKYENKEQHDEYTRIAFAKSEQLKNLIEDLFEYTKLTNEQVVLEKQEVCVNELLEQLIEELVPQAE--HGLTFVKKFPEERAYAAI----DSEKMVRVFDNLLMN-AIKYSKDDGEIKVSLQRQRWEIQ----VIANHSEEFTR--EELASLFERFYKKDQSRSRVTEGSG-LGLAIAK--SIVELQGGSIRAEYKD.................... 487
55 -9.890IDP04302 sensor histidine kinase [Clostridium perfringens ATCC 13124] CPF_2503 [Clostridium perfringens ATCC 13124]  ali follow..  10  65..........................................................................................................................................................................ENVYEDVDIFWKQTDAQVQIYNLKGQLIMDSIGLEPKEYNTP-VDVKRALEGDTAKWVGTVPDYTGKVMAISAPLRNSS-VIRYISSLRNVDNFILNFFLVFLVIGLTVLAIGIILSYFLANSIVNPITELIKVSEQMAKG--NLKVRNKIVTNDEIEKLADSLNIMAEEIENR----ILKNEFISSVSHE------------------LRTPLTSIKGWAITLNNDFTDRETLKMGFDIIEKEADRLSNMVEELLD-FSKFVSGKIKLKNLKEFIEYLRLYMNPRAEREHKELI---KGITEDFIIVGDKDRLKQ--------FINIIDNAFKFTHENEKIIIDTGCGISK--EELPRVKEKFYKGKNSKSQNGIGLSICDEIIA-----LHEGTLEIYSELGKGTKV................ 454
56 -9.880IDP04076 sensor histidine kinase [Bacillus anthracis str. `Ames Ancestor`] GBAA2213 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  11  137..........................................................................................................................................................................................................................................................SLEMTERLDSLQENLNMLKNVLVIASLLVLIPSFFAGRMLSKFILKPVNSLIQTMEHIQVRGIFKKIPLENKSKDELHKMGSTFNKMIDLLHQNFEKQQQ----VSDASHELRTSYAKLLKRQDVLEESVEAIYSEAVRMKGMTNQMLLLANSSADWSLETNESDLV--RLCQVTAEQLE-VNIDEQKIKQVLVVLNAMKYSKDSIDIIVGIQKEKV-DYGMG--IPKEDIQKVFDR-----------VDKARSRETGGTGL----GLSIKQIIDAHEGDIQLESEEGKWTK..................................................... 443
57 -9.870IDP00013 LPXTG-motif cell wall anchor domain protein BA_3254 [Bacillus anthracis str. Ames]  ali follow..  10  31.......................................................................................................................................................................................................................................................................................................TPQQSTGDRLAEIKQHKQGLDAKLQ-QHKENVDQTLNELNKVKENVDTKVNELHERKQVADEKINEIKQHKQELDAKLQQDKQIAEDKIAEIKEHKKQVEDKVAEVKEHKQNIDNKVNEIKEHKQTVDEKVNEMKQKENIDQKVNELKEVKKQVDEKLAELKKAKQTAEDKLAELKENKPNTGNTLEELKKIKSNLDSLSANL-ELAKQDVKNKLAALQEARQDLINKINEIQSKQTVSDDLSKKKQDLDIKINDFKHTEKKIDDKLAEIHTTKQNIDNKINEVSQSKQTETKTGT.... 326
58 -9.860IDP04258 sensory box histidine kinase [Clostridium perfringens ATCC 13124] CPF_2010 [Clostridium perfringens ATCC 13124]  ali follow..  12  59..........................................................................................................................................................................KSELERIESNNDMKNIRITYISKDGNVIFDTHKKLINDNESYLKRQEIIEAIESGLGSSVRYSNDLHQNMIYSALK--GSIVRTSIAVENAKILDSINSNYLLVGVILSLVIALLLTVKITNIILNPLKELEQLTSTIASGNFHKRVKIN-SKDDEIQRLGKSFNYMAEQLEITMERFKDKQNGLEAILKSMGSG---IAFDRDMNVLMINPYAKKIFGISGEIIGNKLLDYITDKEVLKAFFDEKDRVEIEVNYNDDPKILKIRKASIIN--PEIIGT-----VVVIQDITDIKKLENMRSQFANISHELKTPLTSIKGFAETLRYV--DDDETRNKFLSIIDEESDRLARLLEDILCLYEI--EQKRSTVLEEFNVDEIEKVYMLLNDQAKKKGVEIFLDTNSNCVLMGDKDKFKQML..... 468
59 -9.700IDP04419 sensor histidine kinase SrrB, putative [Bacillus anthracis str. `Ames Ancestor`] GBAA2861 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  13  143..........................................................................................................................................................................................................................................................LILVGVSIAHSNEIIKTLNSFYLFILVITIFLIIVLVWILSKTITTPLKELSDVAEDISRLQFK---KTKVKTNDEIGDLATSINIMSEKLQEAHQDLTDRNEHLKRFMGDVTH--------------ELKTPIALVKAYSMGIKDGLDDGTYIDTIIKQSDHIS----NLIEELLR-FSKLERDVLQKESIKSLVQSILDKHKIELESKEINLQVNYNVGD--AIVYADVNKMRM--------FQNLISNAIKYTSNQN-QIQNGMNAEHM--KDIDKIWEPFYVLESSRSKDRSGTG-LGLAIVKSIVERHGFDYGVVTIGGEIR.................. 450
60 -9.670IDP90965 Sensory box/GGDEF family protein VF0094 [Vibrio fischeri ES114]  ali follow..  14  8KQFSLRTAVMLPFIAVLLVTLSIVFYTQNNSYEKLVGDVSEKVLASYTQNTHADLNIFLNAPNFAVKSMVNQIQRYQMYHPNDTKQLQQFLKDSLEGIYTGLEQMDNIRTVIANYDPRSRPWYKPAATTFKPSWSKIYTNADEKEITISTMHPVFYDEDFIGVFAADVKLDSFNKFLSQETKHTKGVIYLIDDQQRLIAHSSVGTIQQSATYIKNNQLINNKNNDAEVFSFYYKGERYFSQITPY-NLNWYIVISISESDLLGHLQEEQRRGLFFGIVLAAIGLIVGVYLVTQVTKPIFTTANAARNIASGNWNNNVEAQGS---ETTLLMNAFNDMTNKLQSSFDAMRQQIDSLTQVLSRQG--RIMLDKKEHYEQGLLVIGINNFRDINDSFGILEGDQRLQCSFAHDNIAIARVGGDEFALFFSKLDDVEQLKQYARDMEGCFMGLVYSMTLWLRNASIALGQAKKNNLNMSLYTPEMAEASLHKANMTAELSLAIKNK--PLAEENGMIIPMGSVLTQACLDTVERIDMHVNLSVCQLTQNNFLDELKAVLHNTSEITE--SRLVNHDNSTINTMQKRDLGVQIAIDDF.. 761
61 -9.640IDP04550 sensor histidine kinase [Clostridium perfringens ATCC 13124] CPF_0460 [Clostridium perfringens ATCC 13124]  ali follow..  9  446................................................................................................................................................................................................................................................................................IFGVVIYSGILFYFGRKYIDKWKKDYNKILEKTKEISNG--NLDSKDDED-CGFFNPMRDELNNIQKGFKAAVDE-RMKTELISNVSHDLKTAYVDL--KGEEDEEKRKAYLETLERKSQRLKHLIEDLFEVSKATTGNINLNIMDVDISYLMKQVVLELDDKINE--------AGLDMRLSLPEEKVILPL-----------------------GQRTYRVFENLIINVVKYALPNSRVYIDIKEGRENVDVIIKNISEISDRFVRGDKSRNTEGSGLGLAIVK---------SFVE-LQGGKFHIEVDGDLFKAIIS.... 739
62 -9.570IDP92003 sensor histidine kinase [Streptococcus pneumoniae str. Canada MDR_19A] SpneCM_010100002775 [Streptococcus pneumoniae str. Canada MDR_19A]  ali follow..  12  34..........................................................................................................................................................................................................................................................................GEIYFLLGMTIVASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAK--DFPSNLEVQGPVEFQQLGQTFNEMSHDLQVSFDSLEESEREIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLATIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKL------LIECMSEFQFLIEQERRVHLQVIPESA----------RIEGDYAKLSR--------LVNLVDNAFKYSAPGTKLEVVAKLEKDQLSISVEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG................. 334
63 -9.350IDP92700 hypothetical protein SAVC_07990 [Staphylococcus aureus subsp. aureus VC40] YP_005291191 [Staphylococcus aureus subsp. aureus VC40]  ali follow..  13 1660...................................................................................................................................................................................................................................................................................................RAALDSIEENNKNQLDAIRNTLDTTQDERDVAIDTLNKIVNTIKN-NAEVDRTETDGNDNIKVILPKVQVKPAARQSVGVKAEAQNALIDQTEEERLAAKHLVEQALNQAIDQINHADKTAQVNQDSINAQNII-TALQQIQNIATNKINLIK-VEKELIKAK--QIASAVTNADVAYLLHDEKNEIREIEPVINRKASAREQLTTLFNDKKQAIEANIQATVEERNSILAQLQNI--YDTAIGQIDQDRSNASLNLQTIHDAEKTINDDLARVTALVQNYRKVSNRNKADA............ 1999
64 -9.200IDP95462 sensor histidine kinase [Staphylococcus aureus subsp. aureus USA300_FPR3757] YP_494944 [Staphylococcus aureus subsp. aureus USA300_FPR3757]  ali follow..  11  146...........................................................................................................................................................................................................................................................SIAVFMRPDIGETFSEFRTFLAVLLMLLLFISISLVIASTYSIIRPVKKLKLATERLIDG--DFETPIKQTRKDEIGTLQYHFNKMRESLGQV----QMRQHFVQNVSHEIKTPLTHIHHLLSELQQTSDK-----TLRQQYINDIYTITTQLSGLTTELLLLSELDNHQHLLFDDKIQ-----NQLIKDIIRHEQFAADEKSLIILADLESINFLGNQRLLHQALSNLLIN-AIKYTDVGGAIDIALQHSHNNII----TISNDGSPISP--QAEARLFERFYKVSKHDNSNGLGLA-ITKSIIELHHGTIQFTQSNEYVTTFTITLPNNS............ 456
65 -9.110IDP04343 two-component system sensor kinase [Yersinia pestis CO92] YPO2916 [Yersinia pestis CO92]  ali follow..  12  165.............................................................................................................................................................................................................................................................IFSRGQQLQKDIAERGQFFGWQSLLLFLVSVLLVVLFTRMIIGPVKGIERMINRLGEGR-SLGNTALFKGPRELRSLAQRIIWLSERLAWLESQLRHISHELKTPLASMREGTELLADETQDQQEVVAILDHSSRHLQQLIEQLLDYNRKLADGPGEPEHVDLA--EMVGNVISAHS-CWAEPTLLMRVL---------DNLYS-NAVHYGEESGTANTGAPIPTSEEIMIFEPFFQGSHQRKGAVKGSGLGLSIAQDCIRRMQGDL-QLVTVDYAAVCFRIELPLTAENE................................................... 483
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Friedberg I, Godzik A. Fragnostic: walking through protein structure space. Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W249-51.