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Query: IDP02492 gene: proC; pyrroline-5-carboxylate reductase [Francisella tularensis subsp. tularensis SCHU S4] FTT1559c [Francisella tularensis subsp. tularensis SCHU S4], from CSGID

Results of FFAS03 search in CSGID
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MKICFIGGGNMAAAMIAGMTSHGYKSQDIIVFDRNEHKCLNLIKKYNINTSTSLLNTIKLADVLILAIKPQNMFELIKNIRDTVTSTQVIVTVAAGIQTSAYEELFNKEISFARTIPNTPSSLGYGATGIFFNKVIAADKKDLVIDIMQTMGVVTVVEDEKEIDIVAAIASSGPAYYFQFMEHMVEAAIKQGLDKKQAEKLVVQTCLGAAQMALNTNENMSELRKNVTSKKGITYEALNIFEQFNLGGIVDKAIQANIARAQQLAIEFTKLIDNLast
1 -104.000IDP02492 gene: proC; pyrroline-5-carboxylate reductase [Francisella tularensis subsp. tularensis SCHU S4] FTT1559c [Francisella tularensis subsp. tularensis SCHU S4]  ali  100  1MKICFIGGGNMAAAMIAGMTSHGYKSQDIIVFDRNEHKCLNLIKKYNINTSTSLLNTIKLADVLILAIKPQNMFELIKNIRDTVTSTQVIVTVAAGIQTSAYEELFNKEISFARTIPNTPSSLGYGATGIFFNKVIAADKKDLVIDIMQTMGVVTVVEDEKEIDIVAAIASSGPAYYFQFMEHMVEAAIKQGLDKKQAEKLVVQTCLGAAQMALNTNENMSELRKNVTSKKGITYEALNIFEQFNLGGIVDKAIQANIARAQQLAIEFTKLIDN 274
2 -99.400IDP02179 gene: proC; pyrroline-5-carboxylate reductase [Coxiella burnetii RSA 493] CBU_2090 [Coxiella burnetii RSA 493]  ali follow..  37  4SNITFIGGGNMARNIVVGLIANGYDPNRICVTNRSLDKLDFFKEKCGVHTTQDNRQGALNADVVVLAVKPHQIKMVCEELKDILSETKLVISLAVGVTTPLIEKWLGKASRIVRAMPNTPSSVRAGATGLFANETVDKDQKNLAESIMRAVGLVIWVSSEDQIEKIAALSGSGPAYIFLIMEALQEAAEQLGLTKETAELLTEQTVLGAARMALETEQSVVQLRQFVTSPGGTTEQAIKVLESGNLRELFIKALTAAVNRAKELSKTVDQ.... 274
3 -85.500IDP00140 pyrroline-5-carboxylate reductase, putative BA_0197 [Bacillus anthracis str. Ames]  ali follow..  29  5HRILFIGAGRMAEAIFSGLLKTSEYIEEIIVSNRNVEKLDQLRARYNVSTTTDWKQHVTSVDTIVLAMPPSAHEELLAELSPLL-SNQLVVTVAAGISPSYLEERLPGGTPVAWIMPNTAAEIGKSISLYTMGQFVNETHQETLQLLLRGIGTSQLC-TEEEVHQLTAVTGSAPAFLYYFAESLIEATKSYGVDEATAKHLVIQMISGSASML-EQTQDPANLREQVTTPGGSTAEGLKAL................................. 244
4 -27.600IDP90565 ketol-acid reductoisomerase [Vibrio cholerae O1 biovar eltor str. N16961] VC0162 [Vibrio cholerae O1 biovar El Tor str. N16961]  ali follow..  12  38KKVVIVGCGAQGLNQGLNMRDSGLDVS-LRQAAIDEQRQSFKNAKNNGFNVGSYEQLIPTADLVINLTPDKQHTSVVNAVMPLMKQGAALG-YSHGFNIVEEGMQIRKDITVVMVAPKCPGTEGFGVPAVHPENDPQGEGWEIAKAWAAATGGHSSFVAEVKSD-LMGEQTILCGMLQAGSIVCYEKMVADGIDPGYAGKLLQFGWETITEALKFGGITHMMDRLSNPAKIKAFELSEELKDRPLYNKHMDDIISGHFSST............. 315
5 -16.600IDP90757 gene: ilvC; ketol-acid reductoisomerase [Campylobacter jejuni subsp. jejuni NCTC 11168] Cj0632 [Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819]  ali follow..  14  19KKVAIIGFGSQGHAHAMNLRDNGV---NVTIGLREGSVSAVKAKNAGFEVV-SVSEASKIADVIMILAPDEIQADIFNVEIKPNLSEGKAIAFAHGFNIHYGQIVVPKGVDVIMIAPKAPGH-GGGTPCLIA-QDESKNAKNLALSYASAIGGGTTFKAETETDLFGEQA----GGLSALIQAGFETLVEAGYEPEMAYFECLHEMKLIVDLIYQGGIADMRYSISNTAEYGDYITGPKIITEE-MKGVLKDIQNGVFAKD............. 291
6 -15.300IDP06064 3-hydroxyacid dehydrogenase [Helicobacter pylori J99] NP_223303 [Helicobacter pylori J99]  ali follow..  16  1MKIGWIGLGAMGTPMATRLRDAGL---EVSVYNRTESKAAPLKEK-GVAVYTSPIDLAAKVDLVFTMLDKAAIDAVLAPKFWEQMSKKIVVSTIAPLESLSLEKIAQKHQATYLEAPVSGSVGAAKAGALLILAAGDEEVISKLKPVLAHLGSQTFYLGKVGQGTGAKLSIN--SLLAQMGVAYSEAAKRLGVDAESFLQIIGQSGMNSPLF.............................................................. 212
7 -14.300IDP04504 2-dehydropantoate 2-reductase [Vibrio cholerae O1 biovar eltor str. N16961] VC2307 [Vibrio cholerae O1 biovar El Tor str. N16961]  ali follow..  15  1MNIVVLGPGAVGSLWALHLHSAG---HQVALWSRQAQPTITLQLD--ISFRNQNLDTLIHADLLLITVKAWQVEAALQPLLPHLNRETILLFMHNGMAVEAISESLTHFPVLFATTLNQVSHTGFGQTQVGPFNALGARCDFIADVFNHALAPVTWNPENCAINPLTAIHQCANGALV-ILDEVTAVMQAEAISGEAEALRDG-----VYQVIQATAANLSSMHQDVFHRRPTEIDFIRKGEQHGIATPVNSALYQQIKTLEQSWSK....... 295
8 -14.100IDP01976 gene: gpsA; glycerol-3-phosphate dehydrogenase (NAD+) [Coxiella burnetii RSA 493] CBU_1518 [Coxiella burnetii RSA 493]  ali follow..  9  7.PIAILGAGSWGTALALVLARKGQKVDEMQAEGVNNRYLPNYPFPETLKAYCDLKASLEGVTDILIVVPSFAFHEVITRMKPLIDAKTRIAWGTKGLAKGSVATELGQVPMAVISGPSLATEVAANLPTAVSLASNNSQFSKDLIERLHGIGVELCGSVKNILAIATGISNARAALITRGLTEMGRLVSVFGGKQETLTGLA-----GLGDLVLVDKKEAQQAIGQAIEGLYNTDQVHALAQKHAIEMPLTFQVHRILHEDLDPQQAVQELLER 327
9 -13.700IDP01730 gene: gpsA; glycerol-3-phosphate dehydrogenase (NAD(P)+) [Francisella tularensis subsp. tularensis SCHU S4] FTT0871 [Francisella tularensis subsp. tularensis SCHU S4]  ali follow..  12  4.NILVLGAGAWGTALALQLAYRG---HNVRINSWKAEHNEQMLKD-RLKAIQDWQANIIEFDSILVATPSSGFKNTILELKECILPQQNIISATKGFCHDSAEDILPTTKFALLTGPSFAKELANQLPTAVVVASKDINYARYVQELFSNIGAQVGGAVKNVLAITAGIANAHAALITRGLAEIKKLGLKLGANSETFIGLSFGLYLGQGMTIQQALKEVNNVVEGYF----TAKAVYNLAKKHNVEMPLVFATYRILYEAADPRDIVKELMTR 326
10 -13.400IDP02330 gene: ilvC-1; ketol-acid reductoisomerase [Bacillus anthracis str. `Ames Ancestor`] GBAA1419 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  11  18KKVAIIGYGSQGHAHAQNLRDNGF---DVVVGLRKGKSWDKAKED-GFSVY-TVAEAAKQADVVMILLPDELQPEVYEEIAPNLQAGNSLV-FAHGFNVHFDQVKPPVNVDVFLVAPKGPGSEGGAVPALFA-QDATGVATEKALSYADGIGATR---KEETETDLFGEQAVLCGGVTALVKAGFETLVDAGYQPELAYFECLHELKLIVDLMYEGGLENMRYSVSDTAQWGDFVSG-PRVVTEDTKKAMGTVLAEIQDGT............. 285
11 -13.200IDP05722 gene: tyrA; prephenate dehydrogenase [Bacillus anthracis str. Ames] BA_2954 [Bacillus anthracis str. Ames]  ali follow..  16  16.KVVLIGTGLIGGSLALAIKKDHDV--TITGYDIFQEQVERAKELHVVEIAVDLQHACEEAHLIVFASPVEETKKLLHKLASFHLREDVIVTDVGSTKMNEAEALFSKEISFIGGHPAKAHLFENAFYILTPMHHVPNEHVEELKDWLKGTGSHFLVLNTEEHDYVTGIVSHFP---HLIAAGLVKQVEKHAGDNPLIHQLAAG---GFKDITRIASSSPKMWSDIVKQNREHLMVLLKEWISEDLYDTVSGEIQNYFADAKEYRDSLPVR... 298
12 -12.900IDP02668 gene: gpsA; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase [Bacillus anthracis str. `Ames Ancestor`] GBAA1526 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  15  3.KITVVGAGSWGTALAMVLADNGHDMDEINTKHENSRYLPGITLPSTIVAYSSLEEALVDVNVVLIVVPTKAYREVLQDMKKYVAGPTTWIHASKGIEPGTIEEEIPEDLIVVLSGPSHAEEVGLRQATTVTSAAKRMEAAEEVQDLFMNVGVELGGALKNIIALAAGITNAKAALMTRGLTEIARLGRKMGGNPLTFAGLTAGNMLGKGHSLEEVLESMGMVVEGVR----TTKAAHELAEKMEVEMPITAALYDVLFNGNNVKDAVGSLMGR 327
13 -12.300IDP02524 gene: ilvC-2; ketol-acid reductoisomerase [Bacillus anthracis str. `Ames Ancestor`] GBAA1852 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  10  18.TVAVIGYGSQGHAQAQNLRDSGV---EVVVGVRPGKSFEVAKAD-GFEVM-SVSEAVRTAQVVQMLLPDEQQAHVYKAEVEENLREGQMLLFSHGFNIHFGQINPPSYVDVAMVAPKSPGQEGNGVPAVAVHQDATGTALHVALAYAKGVGCTTTFQEETETDLFGEQA----GGVTALVKAGFETLTEGGYRPEIAYFECLHELKLIVDLMYEGGLTNMRHSISDTAEFGDYVTG-SRIVTDETKKEMKRVLTEI--QQGEFAKKWILENQA 295
14 -11.500IDP92082 glycerol-3-phosphate dehydrogenase, putative [Toxoplasma gondii ME49] TGME49_107570 [Toxoplasma gondii ME49]  ali follow..  11  23LRVAVIGSGNWGSVIGKICAQNAERSDIINQKHENVKYLPGHKLPDNLVAVPDVVEACRGADLLVFVMPHQFVAKVCDQLAKAVPSHARAISLLKGLYVEGIRSKLNIVECAALSGANVANDVAREAEATIGHSPDETDTALIWQQLFDKPYFKVNTLPD-----VAGVQLCGAVKNVVALAAGFCDGLGLGTNTKSA------IRLGVEEMK------------QFGMIFFDNVIAETFFDSAGYADVITTVF-GGRNARCAAEFVRQK.... 304
15 -11.400IDP05340 putative oxidoreductase [Clostridium difficile 630] CD3450 [Peptoclostridium difficile 630]  ali follow..  14  4IKMGMIGLGSIAQKAYLPILTKSERFEFVGAFTPNKVKREKICSDYRIMPFDSIESLAKKCDCIFLHSSTETHYEIIKI------------LLNLGVHVKPLASTVSQGEELIELSTKKNLNLMVG----------NRRFCPMYKEIKNNATEIVSINICKHIDTALWLANEDVEIS-SHKLKGKNFSINTSMHRDSGTKLEQVEILSKGKIQRVKNLNVLEIEEGGNLTLKQSGAWVNILKQKGFEDISNHFIDCIENKAQRLLEKIINSVK. 305
16 -11.100IDP92023 glycerol-3-phosphate dehydrogenase, putative [Toxoplasma gondii ME49] TGME49_010260 [Toxoplasma gondii ME49]  ali follow..  12  17LKVSVVGSGNWGSVIAKIVALNAQKTDIINKTHENRKYLPGHKLPENLVALPDVVEACRDSDLLIFIMPHQFATKVCEQLAEAVPGHARAITLLKGLHVENFKTKLDIVDCCVLSGANVANDVAREAEATIGYSPEETDAALIWQQLFDTPYFKVNALPDGAVKNVIAI-AAGFCDGLGLGTNAKTAIIRLGVEEDNIMAETFFDSAGYADVITTVDQIEADLLKGQKLQGTLTTKEVYEVIAA-LFSVTYEIAFNGRDPNDLIRVFKTSEVRQ 368
17 -11.000IDP05101 gene: hbd; 3-hydroxybutyryl-CoA dehydrogenase [Clostridium difficile 630] CD1058 [Peptoclostridium difficile 630]  ali follow..  12  1MKLAVIGSGTMGSGIVQTFASCGH---DVCLKSRTQGAIDKCLALLDKNLSTTNYEDLKDMDLIIEASDMNIKKDVFKLLDELCKEDTILATNTSSLSITEIASSTKRPDKVIGMHFFNPVPM-MKLVEVISGQLTSKVTFDTVFELSKSINKVPVDVSES------------PGFV--------------------VNRILIPMINEAVGIYADGVASKEEIDEAMKLGANHPMGPLALGDLIGLDVVL........................ 238
18 -10.800IDP00126 gene: mviM; putative virulence protein NT01ST1449 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  10  4LRIGIVGLGGIAQKAWLPVLTNTAGWTLQGAWSPSRDKALRICESWRIPYVDSLANLASSCDAVFVHSSTAVVSELLNAGVHVCVDKPLAENLRDAERLVALAAQKKLTLMV-RFAPELKTRLGTAASLRMDKHRTDSVGPHDLRFTLLDDYL-------HVVDTALWLAGG---------EARLASGTLLTSESGEMCYAEHHFSADKLQITTSMHRRAGSQRESVQAVTDGGLYDVTDMRE............................... 240
19 -10.700IDP91227 gene: tyrA; T-protein [Escherichia coli CFT073] NT04EC3201 [Escherichia coli CFT073]  ali follow..  10  101.VVIVGGGGQMGRLFEKMLTLSGYQVR------------------LEQHDWDRAADIVSDAGMVIVSVPIHVTEQVIGKLPP-LPKDCILVDLASVKNGPLQAMLAAHDGPVLGLHP--PDSGSLAKQVVVWCDGRKPEAYQWFLEQIQVWGARLHRISAVEHDQNMAFIQALR---HFATFAYGLHLAEENVQLEQLLALSSPIYRLELAMVGRLFAQDPQLYADIIMSSERNLALIKRYYKQGDKQAFIDSFRKVEHWFGDYAQRFQSESRV 363
20 -10.300IDP06299 6-phosphogluconate dehydrogenase [Streptococcus pneumoniae TIGR4] NP_344902 [Streptococcus pneumoniae TIGR4]  ali follow..  13  4ANFGVVGMAVMGRNLALNIESRGY---TVAIYNRSKEKTEDVIAEKNFVPSYDVESFVNSIEKPRRIM--PGTDATIQALLPHLDKGDILIDGGNTFYKDTIRRNEELANSGINFI---GTGVSGGEKGALEGPSIQKEAYELVADVLEEISAKA---PEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYD............................................................................ 203
21 -10.200IDP02226 gene: yqjI; 6-phosphogluconate dehydrogenase [Bacillus anthracis str. `Ames Ancestor`] GBAA0164 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  12  4LQIGVVGVGVMGKSLALNFESKGY---SVALYDISKEKVDETIEE-NLVGTHIVEEFVNSLESPRKIL--EITDKAIDSLVPHLDKGDILIDGGNTYFVDTIRRNKRLAEEGINFI---GAGVSGGEEGALKGPSIQKDAYEKVKDMLENISAKVNNEP-----CCSYIGPNGAGHYVKMVHNGIEYGDMQLICE............................................................................... 198
22 -9.950IDP00461 gene: tyrA; bifunctional chorismate mutase/prephenate dehydrogenase YPO3285 [Yersinia pestis CO92]  ali follow..  9  102..VIIGGQGQMGRLFSRMLNLSGYQVRTL-----------------EQEDWSQAESILADAGMVIVSVPIHITEEVINRL-PKLPADCILLDLASVKNKPLQAMLAAHEGPVLGLHP--PDVGSLAKQVVVYCDGRDPQAYQWLLEQLQVWGARLHRISAVEHDQNMAFIQALR---HFATFAYGLHLAEENVQLEQLLALSSPIYRLELAMVGRLFAQDPQLYADIIMSSEDNLALIKRYYKHHDKQAFVQSFEKVEHWFGDYAERFLVESRS 363
23 -9.070IDP90690 gene: gpsA; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase [Campylobacter jejuni subsp. jejuni NCTC 11168] Cj1196c [Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819]  ali follow..  11  2MRIAVIGAGKWGSALHLALKENH----NCFISSLHQRDLE----------DFVSIKEALECEYLVFALSSQGMRAWLKEN--FINKGQKILIASKGIEDQSFLDFVPKENFCVLSGPSFAAEVMQKLPTALMISGINQELCKKFASFFPDFIKTYIDNDVRGAEICGAYKN-----VLAIASGISDG---LKLGNNARAALISRGLIEMHRFGKFFGTKEE------------TFLGLSGAGD------LFLTATSVLSRNYRVGLKLAQ.... 236
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Godzik A. cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences. Bioinformatics. 2006 May 26;