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Query: IDP02583 3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA hydratase/isomerase family protein [Bacillus anthracis str. `Ames Ancestor`] GBAA5249 [Bacillus anthracis str. `Ames Ancestor`], from CSGID

Results of FFAS03 search in CSGID
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MFQIKKAAVLGSGVMGSGIAAHLANIGIPTLLLDIVPPALTKEEEAKGLTLEHKSVRNRFSNTAVQKLLKQKPAPLTVKGNLALIEAGNLEDDLERLADVDWIIEVVVENLDIKKKLFEKVDAVRKPGSIVSSNTSGISVEKMAEGRSDDFQKHFLGTHFFNPPRYLKLLEVIPTKKTDPQVLSFMKLFGEDVLGKGVVIAKDTPNFIGNRIGTYGLLVTLQEMVKRGYSIGEVDSVTGPLIGRPKSATFRTLDVVGLDTFVYVANNVYENVQEKERDVFKVPAFMHDMLDKKWLGSKTGQGFFLKQGKEILELNPETMEYEARKKLKAASIELSKQEKGLSNKLKALVYAKDRAGELLWNIITPTLLYSAKLHKEIADDIVAIDQAMKWGFGWEQGPFEVWDAIGVEKSVQKMEESGAVIPAWVKEMLEKGFTTFYKHDNGDSYYYDNGEYKLIECNKKAISLKQLKAKNGVLKKNSGASLIDLGDGILCLEFHSKSNAIGMDITQMINYAVDEVEKNYKGLVIGNQSKNFCVGANLAMILMEAQDDNYFEIEWVVKNFQDAMMKIKYSSKPVVAAPYGMTLGGGTEVCLPAASIQASSETYMGLVEVGVGLIPGGGGNKELYIKHLNKMANGVEFDLQKVANKVFETVAMAKVLTSGQEAVSHNFLGDKDGISVNGDHLLYDAKQKALALYEAGYKAPIRKKIPVVGETGYATLALGAEAMHLSGYISEYDLHIAKKLAYVIAGGKVPYGTEVDEQYLLDVEREAFISLVSEMKSQARMQHMLVKGKPLRNLast
1 -196.000IDP02583 3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA hydratase/isomerase family protein [Bacillus anthracis str. `Ames Ancestor`] GBAA5249 [Bacillus anthracis str. `Ames Ancestor`]  ali  100  1MFQIKKAAVLGSGVMGSGIAAHLANIGIPTLLLDIVPPALTKEEEAKGLTLEHKSVRNRFSNTAVQKLLKQKPAPLTVKGNLALIEAGNLEDDLERLADVDWIIEVVVENLDIKKKLFEKVDAVRKPGSIVSSNTSGISVEKMAEGRSDDFQKHFLGTHFFNPPRYLKLLEVIPTKKTDPQVLSFMKLFGEDVLGKGVVIAKDTPNFIGNRIGTYGLLVTLQEMVKRGYSIGEVDSVTGPLIGRPKSATFRTLDVVGLDTFVYVANNVYENVQEKERDVFKVPAFMHDMLDKKWLGSKTGQGFFLKQGKEILELNPETMEYEARKKLKAASIELSKQEKGLSNKLKALVYAKDRAGELLWNIITPTLLYSAKLHKEIADDIVAIDQAMKWGFGWEQGPFEVWDAIGVEKSVQKMEESGAVIPAWVKEMLEKGFTTFYKHDNGDSYYYDNGEYKLIECNKKAISLKQLKAKNGVLKKNSGASLIDLGDGILCLEFHSKSNAIGMDITQMINYAVDEVEKNYKGLVIGNQSKNFCVGANLAMILMEAQDDNYFEIEWVVKNFQDAMMKIKYSSKPVVAAPYGMTLGGGTEVCLPAASIQASSETYMGLVEVGVGLIPGGGGNKELYIKHLNKMANGVEFDLQKVANKVFETVAMAKVLTSGQEAVSHNFLGDKDGISVNGDHLLYDAKQKALALYEAGYKAPIRKKIPVVGETGYATLALGAEAMHLSGYISEYDLHIAKKLAYVIAGGKVPYGTEVDEQYLLDVEREAFISLVSEMKSQARMQHMLVKGKPLRN 793
2 -162.000IDP04044 gene: fadB/acbP; fusion product of 3-hydroxacyl-CoA dehydrogenase and acyl-CoA-binding protein [Francisella tularensis subsp. tularensis SCHU S4] FTT1530 [Francisella tularensis subsp. tularensis SCHU S4]  ali follow..  34  114RKAIDKIAVLGAGTMGAQIAAHFANAKFPVVLFDLKSQQGS---------------ANVIIEDSLAKLTKLNPAPFGSKDSIKYITPANYEDNLELLADCDLIIEAVAERIDIKESLYTKISSHIKENAILASNTSGLSITKLAQVLPENLKVNFCGVHFFNPPRYMPLVELIPHADTNSEILDKLETFLVEKLGKSIIRAKDTPNFIANRLGVFSMLVTCYYTEQMSIPLEVVDELTGKKLGRAKSATYRTADLVGLDVLSHVVETMKDNLEDGWQKLYNTPNWIQNLINNGSLGQKTKKGLYIKASDGIKVLDLGTNEYRPADKKADKEILDILAERDWSKKLEGLRNSDNHQAQFLWATFREMFLYAAHLVGDISNFPKDMDLAIRWGFGWKQGIFEIWQLAGWHKVASWLKDDISTGKTNTLPSWIDTLDISVYQNNKEFSYKDKELIRQLFADNIVEHTSTLATQTLYENDGVKLWQIDDYSNIGILSFKSKMCAIGDDVLDGISESINYAEEKLDGLVIWQEQDVFSVGANLEEFGIKFAMNGEAAIEEVIRKGHSIIKKLRYSKIPVVAAVKGFAFGGGCETILHSDAAVAAYESYIGLVEAAVGIIPGWGGSKEMAVRASQAQ------DHWKDFERRYKNLALAQVAKSAYEAKEMGFLRDDDIVVMNTKEILLVAIKKAQLMALAGYQPPLKQKVPVFGETGIATIKALLVNMRDGNQISEHDYKIAVNLADTMCGGQIEKDTEVSEDWLLERELINFKELAISEKTEARMKYMLETGKPLRN 898
3 -73.000IDP00503 gene: fadB; multifunctional fatty acid oxidation complex subunit alpha YPO3766 [Yersinia pestis CO92]  ali follow..  22  311.AAPKLAAVLGAGIMGGGIAYQSALKSVPVIMKDINENSLDLGMNEAAKLLNKQLERGKVDGLKMASILATIRP----------------TLDYAGIERAQVIVEAVVENPKVKAAVLAEVEALIGEDTVLASNTSTIPIDQLAKSLKR--PENFCGMHFFNPVHRMPLVEIIRGAKTSDKTLAAVVAYATQ-MGKTPIVVNDCPGFFVNRVLFPYLAGFGMLVRD-GGDFHQIDKVMEKQFGWP-MGPAYLLDVVGIDTAHHAQAVMAAGFPERMNKDY--RDAVDVMFDNQRFGQKNGQGFYRYTQDAKGKPRKENDEQVDKLLAEISQPL-----------------QEFSDEDIIARTMIPMINEVVRCLEEGIASAAEGDMALVYGLGFPPGVFRYLDTLGSANYVEMAQRYAHLHVPAGLRAKAEHNESYYPVAAALLDVSTNQP...................................................................................................................................................................................................................................................................................................................................................... 728
4 -71.300IDP05101 gene: hbd; 3-hydroxybutyryl-CoA dehydrogenase [Clostridium difficile 630] CD1058 [Peptoclostridium difficile 630]  ali follow..  26  1....MKLAVIGSGTMGSGIVQTFASCGHDVCLKSRTQGAIDKCLALLDKNLTKLVTKGKMDEATKAEILSHV----------------SSTTNYEDLKDMDLIIEASVEDMNIKKDVFKLLDELCKEDTILATNTSSLSITEIASSTKR--PDKVIGMHFFNPVPMMKLVEVISGQLTSKVTFDTVFELSKS-INKVPVDVSESPGFVVNRILIPMINEAVGIYADGVASKEEIDEAMKLGANHP-MGPLALGDLIGLDVVLAIMNVLYTEFGD---TKYRPHPLLAKMVRANQLGRKTKIGFYDYNK..................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 281
5 -69.000IDP00999 gene: fadJ; multifunctional fatty acid oxidation complex subunit alpha STM2388 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  20  307.PLNSVGILGGGLMGGGIAWVTACKGGLPVRIKDINTQGINHALKYSWDLLETKVRRRHIKASERDKQLALISG----------------STDYRGFSHRDLVIEAVFEDLPLKQQMVAEVEQNCAAHTIFASNTSSLPIGDIAANAAR--PEQVIGLHFFSPVEKMPLVEVIPHASTSAQTIATTVKLAKK-QGKTPIVVSDKAGFYVNRILAPYINEAIRMLTE-GERVEHIDAALVK-FGFP-VGPIQLLDEVGIDTGTKIIPVLEAAYGERFS---APANVVASILNDDRKGRKNGRGFYLYGEK--------------------GRKSKKQVDPAIYKLIGVQGQSRLSAQQVAERCVMLMLNEAARCFDEKVRSARDGDIGAVFGIGFPPGPFRYMDALGPGEMVATLQRLAALYPCEQLVRMAERREHFWTNGET............................................................................................................................................................................................................................................................................................................................................................... 711
6 -68.100IDP00545 gene: fadJ; multifunctional fatty acid oxidation complex subunit alpha YPO2747 [Yersinia pestis CO92]  ali follow..  19  343...HRVGVLGGGLMGGGIANVTATRAGLPVRIKDINPQGINQALKYTWDALGKRVRSKRMRPTEQQRQMMLISG----------------STDYRGFERVDIVVEAVFEDLSLKQQMVADIERFGAAHTIFASNTSSLPISQIAALAQR--PEQVIGLHYFSPVDKMPLVEVIPHEKTSEETIATTVALARK-QGKTAIVVADRAGFYVNRILAPYINEAARCLLD-GEPIESVDNALVD-FGFP-VGPMMLLDEVGIDVATKIMPILVEQLGPR----FAAPPSFDVILKDGRKGRKNGRGFYLYSNPTKNSSPTKNGNSPAKRNSFKWRKNKVKPVASIYTLLGVTPKAHLGAGVITQRCTMLMLNEAVRCLDESIRNPRDGDIGAVFGIGFPPGPFRYLDSLGADKVVQALRLLVQQYGERFEPCQRLVTMA--EQQQQFYPVDANIDEVTDVAS............................................................................................................................................................................................................................................................................................................................................... 774
7 -67.100IDP04410 fatty oxidation complex, alpha subunit [Vibrio cholerae O1 biovar El Tor str. N16961] VC1047 [Vibrio cholerae O1 biovar El Tor str. N16961]  ali follow..  21  327.APVAAVGVLGGGLMGAGISHVVAKAKTSVRIKDVANDGVLNALNYNYKLFDKQRQRKILTKAQLQAQMSQLSG----------------GTGFVGFDRCDVVIEAVFEDLKLKQQMVADIEANAKPTTIFATNTSSLPIHQIASQAQR--PQNIVGLHYFSPVEKMPLVEVIPHATTSDETIATVVTLARK-QGKTPIVVKDCAGFYVNRILAPYMNEAAQVLMA-GEPIEKLDAALLD-FGFP-VGPITLLDEVGVDIGAKIMPILVKELGPR----FQGPDVFDVLLKDNRKGRKSGKGFYTYKGSKKKEVDKSVYKLLKLTPESKLNDK-----------------------EIAMRCLLPMLNEAVRCLDEIIRSARDGDMGAIFGIGFPPGPFRYMDTLGLTKVVEMMNQHTEKYPCDGLLTRAGLGEKFY.................................................................................................................................................................................................................................................................................................................................................................... 723
8 -44.700IDP04689 enoyl-CoA hydratase [Bacillus anthracis str. `Ames Ancestor`] GBAA4761 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  20  3.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................KFLSVRVEDHIAVATLNHAPANAMSSQVMHDVTELIDQVEKDIRVVVIHGEGRFFSAGADIKEF---TSVTEAKQATELAQLGQVTFERVEKCSKPVIAAIHGAALGGGLEFAMSCHMRFATESAKLGLPELTLGLIPGFAGTQRLPR--------------YVGKAKACEMMLTSTPI-TGAEALKWGLVNG----VFAEETFLDDTLKVAKQIAGKS------------------------------------------PATARAVLELLQTTKSSHYYEGVQREAQIFGEVFTSEDGREGVAAFLEKRKP... 253
9 -42.500IDP02329 enoyl-CoA hydratase [Bacillus anthracis str. `Ames Ancestor`] GBAA2551 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  21  5...........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................QNISVDYATPHVVKISLNRERQANSLSLALLEELQNILTQINEETRVVILTGAGKAFCAGADLKERAGM----NEEQVRHAVSMIRTTMEMVEQLPQPVIAAINGIALGGGTELSLACDFRIAAESASLGLTETTLAIIPGAGGTQRLPR--------------LIGVGRAKELIYTGRRI-SAQEAKEYGLVEF----VVPVHLLEEKAIEIAEKIASNG------------------------------------------PIAVRLAKEAISNGIQVDLHTGLQMEKQAYEGVIHTKDRLEGLQAFKEKRTP... 257
10 -38.200IDP04059 naphthoate synthase [Vibrio cholerae O1 biovar El Tor str. N16961] VC1973 [Vibrio cholerae O1 biovar El Tor str. N16961]  ali follow..  15  46.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................AKITIARPQVRNAFRPLTVKEMIHALADARYDVGVIILTGLGDAFCSGGDQKIRGDYGGYRD--DSGTHHLNVLDFQRQIRTCPKPVIAAVAGWAVGGGHVLHMMCDLTIAAENAQFGQTGPKVGSFDGGWGASYMAR--------------IVGQKKAREIWFLCRFY-NAQEALDMGLVNT----VVPVEELERETVRWCREVLQHS-------------------------------------------MAIRCLKAALNADCDGQAG-LQELAGNATMLFYMTEEGQEGRNAFNEKRRP... 287
11 -37.500IDP00995 gene: menB; naphthoate synthase STM2307 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  15  23...........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................TDIRYEKSTDGIAKITINRPQVRNAFRPLTVKEMIQALADARYDVGVIILTGEGKAFCAGGDQKVRGDYGGYQDDSGV--HHLNVLDFQRQIRTCPKPVVAMVAGYSIGGGHVLHMMCDLTIAAENAIFGQTGPKVGSFDGGWGASYMAR--------------IVGQKKAREIWFLCRQY-DAQQALDMGLVNT----VVPLADLEKETVRWCREMLQNS-------------------------------------------MALRCLKAALNADCDGQAG-LQELAGNATMLFYMTEEGQEGRNAFNQKRQP... 276
12 -10.100IDP06064 3-hydroxyacid dehydrogenase [Helicobacter pylori J99] NP_223303 [Helicobacter pylori J99]  ali follow..  13  2.....KIGWIGLGAMGTPMATRLRDAGLEVSVYNRTESKAAPLKEKGVAVYTSPI---------------------------------------DLAAKVDLVFTMLSDKAAIDAVLAPKFWEQMSKKIVVNMSTIAPLESSLEKIAQKH------QATYLEAP---ALLILAAGDEEVISKLKPVLA----HLGSQTFYLGKVGQGTGAKLSGVAYSEALLLAKRLGVDAESFLQIIG.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 203
13 -9.890IDP91765 ThiF family protein [Yersinia pseudotuberculosis IP 32953] YPTB1885 [Yersinia pseudotuberculosis IP 32953]  ali follow..  12  116....ATVGIMGTGGIGSNVAILLAAAGVKLKISDIEESNLTRAT------IFKEDQIGSLKVASLKENISERNKTCGVEVLPLLLNEENMDKFNAFFSECDIIVLSLISIFHDNNNVNAGYLGRLGLIGPMMDATSNPGFKELFTRDCEENRTGKILINRRYQAPSYGPLNYMVSSICSHEVIRYLATRKSCVWQKRLLI................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 320
14 -9.630IDP92100 malate dehydrogenase, putative [Toxoplasma gondii ME49] TGME49_118430 [Toxoplasma gondii ME49]  ali follow..  13  155.MSRRKIGLIGGGNIGATLALLSAVKELDVVMFDVVQDLPQGKCLDLYQLTPISGVDVRFEGS----------------------------NDYSVLKDADVIIDLLAINAKIMGQVGEAIKQYCPNAFVIITNKCGLPLSERLNVSVDDIHALVMGGH-PRFTTVIPLPELVKMGMISQQEVDDIVQRTRNG-GGEIVSLLKT-GSAFFAPAA-AGVLMAEAYLKDRKRVLPCAAYLNGEYGVKDM--VGVPCVIGAGGVEKIVE--LDLTPEEKKMFERSVESVKTLLAA..................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 465
15 -9.290IDP02330 gene: ilvC-1; ketol-acid reductoisomerase [Bacillus anthracis str. `Ames Ancestor`] GBAA1419 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  15  1MAKVKKVAIIGYGSQGHAHAQNLRDNGFDVVVGLRKGKSWDKAKED------------------------------------------SVYTVAEAAKQADVVMILLPDELQPE-VYEEEIAPNLQAGNSLVF-AHGFNVHFDQVKPPVNVD................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 123
16 -9.130IDP02372 gene: mdh; lactate dehydrogenase [Francisella tularensis subsp. tularensis SCHU S4] FTT0535c [Francisella tularensis subsp. tularensis SCHU S4]  ali follow..  11  1.MARKKITLVGAGNIGGTLAHLALIKQLDVVLFDIAQGMPNGKALDLLQTCPIEGVDFKVRGT----------------------------NDYKDLENSDVVIDLLGINIKVMQTVGEGIKHNCPNAFVIITNFSGVPLADELNVSVQQVQAYVMGGH-------VSLEQLVKEGKLKQERLDAIVSRTRSGGGEIVALLKTGSAYYAPAAAGIQMAESFLKDKKMILPCAAK--VKAGMYGLDEDLFVGVPTEISANGVRPIEVEISD---KEREQLQVSINAIKDLNKA..................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 312
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Godzik A. Discovering new genes with advanced homology detection. Trends Biotechnol. 2002 Aug;20(8):315-6.