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Query: IDP04179 methyl-accepting chemotaxis protein [Vibrio cholerae O1 biovar eltor str. N16961] VCA0068 [Vibrio cholerae O1 biovar El Tor str. N16961], from CSGID

Results of FFAS03 search in CSGID
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MRQLLSGLSIKLQVVVPVFFTLLLLIIGITFSTSSLKTAFHQVTVSTEQLITDKDNLTTLIDNTYAMRISAIYSLFRPAEVTALPNVLKEKQTENLALLRSLADNPELKNEVAGLTQAMQRYVDYSIQTMIPLLNIEHSDQEKDERFTAQYEQATAEYRKVGNEMIKAIDVLSNRLNQVAMTTIDESEHEHDSVMSQSTFALIGILLVAALSSWLLAGIIVTPIRQLQQTVREIAKGNLLVKAQEEGNNEITLLARDVNATVTQLRQTVESLVRISTDVASASTELATVMTQASVNSDQEKQEVEQVASAVNQLQSTAQSVTDHAHSADGAAQQANQLASQSLRMFEESHRATAKMADQLREAAQVVNQLKEQSERIGNVTEVIRSISEQTNLLALNAAIEAARAGESGRGFAVVADEVRMLAARTQTSTQEIQAIIEELQNQSNTANSSMHSSLSLLEQNQSLAAKVSASLTEINHSISALGQINAQVATASEEQSQVTKDINRNLSNIYELVSQNVTGITQSAAASHELSDLAEQQHQQLQYFRVLast
1 -90.500IDP04179 methyl-accepting chemotaxis protein [Vibrio cholerae O1 biovar eltor str. N16961] VCA0068 [Vibrio cholerae O1 biovar El Tor str. N16961]  ali  100  1MRQLLSGLSIKLQVVVPVFFTLLLLIIGITFSTSSLKTAFHQVTVSTEQLITDKDNLTTLIDNTYAMRISAIYSLFRPAEVTALPNVLKEKQTENLALLRSLADNPELKNEVAGLTQAMQRYVDYSIQTMIPLLNIEHSDQEKDERFTAQYEQATAEYRKVGNEMIKAIDVLSNRLNQVAMTTIDESEHEHDSVMSQSTFALIGILLVAALSSWLLAGIIVTPIRQLQQTVREIAKGNLLVKAQEEGNNEITLLARDVNATVTQLRQTVESLVRISTDVASASTELATVMTQASVNSDQEKQEVEQVASAVNQLQSTAQSVTDHAHSADGAAQQANQLASQSLRMFEESHRATAKMADQLREAAQVVNQLKEQSERIGNVTEVIRSISEQTNLLALNAAIEAARAGESGRGFAVVADEVRMLAARTQTSTQEIQAIIEELQNQSNTANSSMHSSLSLLEQNQSLAAKVSASLTEINHSISALGQINAQVATASEEQSQVTKDINRNLSNIYELVSQNVTGITQSAAASHELSDLAEQQHQQLQYFRV 547
2 -84.600IDP01485 hemolysin secretion protein HylB VCA0220 [Vibrio cholerae O1 biovar El Tor str. N16961]  ali follow..  25  2...IINKFSLKWMLAIAVAIPAIALLFVAFTSLNTMSVMQAQSNSLYANTAAPMRAMAEATSRIPRMRVGIDMMLLQETALKDAKGVLKRVEEARTEDIPEMRQAMQVAVDSQVNPELKEQARKLQARFEQREELEPMLQAFANNDMTTAQNIYRDKYAPTYGEMRKQANQILDTLLQQAEQQNHASVESFEAGRTKQMVIIAAGLIISFITSLVIITNLRSRVAYLKDRMSSAANLSLRTRLELDGNDELCDIGKSFNAFIDKVHHSIEEVAENSKELATMASSVSQRAHMTQSNCASQRDRTVQVATAIHELGATVSEIASNAAMAADVAKQATLHSGEGKKVVGEVQNRIQTLVNELDNATQVVSSLATQINGISSTLDTIRSISEQTNLLALNAAIEAARAGEQGRGFAVVADEVRTLASRSAASTEEIQQVINRLQTESTRAVEAMEKGRSQSDVVVEFSAKANQSLTEINSQIDQINDQNIQVATATEEQSTVVEDINRNVEDINQLTTETSHVADELSRASASLQRLSSQLDKLVGSFEL 548
3 -67.000IDP95280 methyl-accepting chemotaxis protein [Acinetobacter baumannii ATCC 17978] YP_001085820 [Acinetobacter baumannii ATCC 17978]  ali follow..  28  293.......................................................................................................................................................................................................................EYDRNQNAILRLLDEIADLADGDLRSYATV-SEDFTGAIADSINFAIDQLRDLVSRIHETSQEVARYTQDTQSITNQLAEASEHQAQEIAGASTAMNEMAQSIDQVSANASESAEVAQRSVQIASNGAQVVNRSIEGMDTIREQIQETSKRIKRLGESSQEIGNIVSLINDIADQTNILALNAAIQASMAGEAGRGFAVVADEVQRLAERSASATKQIETLVKTIQTDTNEAVISMEQTTTEVVRGANLAKDAGIALDEIQKVSGDLAKLIASISDAAKLQSASASHIATTMTVVQEITSQTTTATFDTARSVSELANMAESLRESVTDFKL 623
4 -66.000IDP91343 methyl-accepting chemotaxis protein [Vibrio vulnificus CMCP6] VV2_0072 [Vibrio vulnificus CMCP6]  ali follow..  31  176............................................................................................................................................................................................................GIWSLLLLSVAISYSSTRRLESLSAEARKVFDNPLMELVYNKKVDDISEIKLALKMRQSELNAVVGRIQDSNQQLIDSARNSSSNSDKASHNLKGQTHETEQVAAAITEMHSTANEIAQNAQSASDATDQAHSAASEGMITVQDTVKAIKLLAGQLDETSDVVSQLAQHGKTIGDVLIIIQGVAEQTNLLALNAAIEAARAGEQGRGFAVVADEVRKLAQRSHESTEEIQKVIGLIQSSTQKAVSSMSEGTHLAEQCVSSADSSGQKLQILLDQVTDISDRNNQIATAVEEMARVTEDMSSSVQSISDACSATNVLSSDTCHQCNALVKSLDSQGKLVSQFR. 517
5 -54.500IDP02460 gene: cheD; methyl-accepting chemotaxis protein [Yersinia pestis CO92] YPO1675 [Yersinia pestis CO92]  ali follow..  20  1...MFKRMKVVTSLLLVLVLFGALQLVSGGLFFKSLQNDQENFNVLQVIRQQQSVLNESWVYLLQTRNTLNRAGVRSGPTVKDLISSAKGTLSVAEDRFKRYEKIPQNSSQDPEGAKKLKQSYEEYFSALTELINLM--------ETNKINEFFNHPTTSFQNEFEQNYNNYLTQNDGLYDSAVEDSNQSFSFAMGVVITVLVVVLVMMLLVWLGMQQILIHPLNHLIAHIKHIANGDLTQNIEVHGRNEVGTLAASLKHMQSELVTIVGEVRVGADAIYSGASEIAVGNNDLSARTEQQAASLEETAASMEQLTATVKQNAENARQASQLALSASETAQKGGKVVADVVQTMHEIAGS--------------SQKIADITSVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRNLAQRSAQAAKEIKGLID--------------DSVNRVDLGSVLVESAGETMGDIVNAVTRVTDIMGEIASASDEQSRGIDQIGQAVAEMDRVTQQNASLVEESASAAASLEEQASMLTQAMSVFVL 517
6 -54.400IDP01047 putative methyl-accepting chemotaxis protein STM3152 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  22  1.MRLLQNFTIRMVMLTILGLFCLLWSGVGLYSVHALSEV-SEGNDIDRHLVRQMTVLSQGNDQYFRFVTRLSRAMDKIGGGTPDFAPARQSLENMRQKLEEMKALSPGPMNPDISREVLSNWQALLEKGVVPQMQ-----LAQQGSLTAWSEHASTVTPALSRAFGASAERFSHEAGAMLDNTRVMVDGKTYTIRILLITAVILGIAILIFTDRYLVAMMVKPLERIRQQFQRIAQGDLSQPIEALGRNCVGRLVPLLRAMQDSLREAVSTIRAGSDNIWRGATEISTGNNDLSSRTEEQAAALEETAASMEQLTATVKMNAEHARQASQLADAASLTAGKGGELVSDVVETMNGISAS--------------SQQIAEITTVINSIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRNLASRSAGAAKEIEALIG--------------ESVRRVAQGAQLVQETGATMDAILRGVTEVTTIMKQIASASEEQSKGISQVGVAITQMDSVTQQNAALVEQVSAAAAALERQTEDLQRSVQQFRL 513
7 -54.300IDP01940 gene: trg; methyl-accepting chemotaxis protein III [Salmonella typhimurium LT2] STM1626 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  23  13.LGFLHHIRLVPLFSSILGGILLLFALSAGLAGYFLLQADRDQRDVTDEIQVRMGLSNSANHRINMIHAGAASRIAEMDEMKANIAAAETRIKQSQDGFNAYMSRAVKTPADDALDNELNARYTAYINGLQPMLK-----FAKNGMFEAIINHENEQAKQLDAAYNHVLLKAIELRTERARLLSEQAYQRTRLGMMFMIGAFTLALVLTLMTFMVLRRTVIQPLQQSASRIERIAAGDLTMADEPTGRSEIGRLSHHLQQMQHALQQTVGAVRQGAEEIYRGTSEITAGNTDLSSRTEQQAAAIEQTAASMEQLTATVKQNADNAHHASKLAEDASGKASRGGQMVSGVVQTMGNISTS--------------SKKISEITAVINSIAFQTNILALNAAVEAARAGEQGRGFAVVASEVRTLASRSAQAAKEIEGLIG--------------ASVSLIEQGSEEVIAAGSTMNEIVDAVKRVTDIMLDIAAASDEQSRGIVQVSQAISEMDRVTQQNASLVEEASAAARSLEEQAARLTQAVDAFRL 529
8 -54.100IDP02090 gene: tcp; methyl-accepting transmembrane citrate/phenol chemoreceptor [Salmonella typhimurium LT2] STM3577 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  21  1....MKNIKVITGVIATLGIFSALLLVTGILFYSAVSSDRLNFQNASALSYQQQELGGSFQTLIETRVTINRVAIRSLDAMNTLLTNAGASLNEAEKHFNNYVNSEAIAGKDPALDAQAEASFKQMYDVLQQSIHYL--------KADNYAAYGNLDAQKAQDDMEQVYDQWLSQNAQLIKLASDQNQSSFTQMQWTLGIILLIVLIVLAFIWLGLQRVLLRPLQRIMAHIQTIADGDLTHEIEAEGRSEMGQLAAGLKTMQQSLIRTVSAVRDNADSIYTGAGEISAGSSDLSSRTEQQASALEETAASMEQLTATVRQNTDNARQATGLAKTASETARKGGRVVDNVVSTMNDIAES--------------SEKIVDITSVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRTLASRSAQAAKEIKVLIE--------------NSVSRIDTGSTQVREAGETMKEIVNAVTRVTDIMGEIASASDEQSKGIEQVAQAVSEMDSVTQQNASLVEESAAAAAALEDQANELRQAVAAFRI 516
9 -53.900IDP01089 gene: tsr; methyl-accepting chemotaxis protein I STM4533 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  22  1...MLKRIKIVTSLLLVLALFGLLQLTSGGLFFNSLKNDKENFTVLQTIRQQQSALNATWVELLQTRNTLNRAGIRSGATVAELMQGATNTLKLTEKNWEQYEALPRDPRQSEAAFLEIKRTYDIYHGALAELIQLLGA---------KINEFFDQPTQSYQDAFEKQYMAYMQQNDRLYDIAVEDNNSSYNQAMWVLVSVLIAVLVVIIAVWFGIKLSLIAPMNRLIESIRHIASGDLVKRIDVEGSNEMGQLAENLRHMQSELMRTVGDVRNGANAIYSGASEIAMGNNDLSSRTEQQAASLEETAASMEQLTATVKQNAENARQASHLALSASETAQKGGKVVDNVVQTMRDIASS--------------SQKIADIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRNLAQRSAQAAREIKSLIE--------------DSVSRVDVGSTLVESAGETMDEIVNAVTRVTDIMGEIASASDEQSRGIDQVGLAVAEMDRVTQQNASLVEESAAAAAALEEQASRLTQAVAVFRI 517
10 -53.200IDP02252 gene: tsr2; putative methyl-accepting chemotaxis protein [Yersinia pestis CO92] YPO1229 [Yersinia pestis CO92]  ali follow..  30  259........................................................................................................................................................................................SQATAGIHSLLTTSLVTLVIIIFISAGVIALITQRALTPLTHIQQAMDAISSGDLTQRLPIEGRDEVAQIARSFNQFADKLSLVMAQIRGTSESVRVAANEIAAGNQDLSGRTESAAASLQQTSAALEQISATVAQSASAARQANNAVFSASEDASRGGDVITKVITT--------------MESIEKASGKIGDITSVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRILAQRSAQAAKEIKALIE--------------STVSSVASGSSQVRQASNAMTDIVSSVSDVTTIMSEITNAADEQMRGIHEINSAVAQLDTMVQQNAALVQESTAASAALQAQAADLTDTVNQFKI 595
11 -53.100IDP02076 putative methyl-accepting chemotaxis protein [Salmonella typhimurium LT2] STM3216 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  21  3....LHNIKIRSKLFMAFGLFIVLMVVSSALSLFSLDRANTGMQNIITNDYPTTVKANLLIDNFNDFIIAQQLMLLDEESSQKELDEISQRITALLDELSSNRHDAASQKIITEIREARQQYLESRFRILQ---------DIQSHNRQAAIQEMMTRTVQVQKVYKDKVQELIAVQDAQMHNAGVQVEGDFKTNRTLLITLALISIAAGCVMGWYIVRSITRPLDEAVRFAEAIADGDLTRHITTDYKDETGVLLQALMAMKTRLLDIVQEVQNGSESISTAAAQIVAGNQDLAARTEEQASSVEETAASMEQITATVKNTADHTSEATKLSAGAASVVKNNGEMMNQVTQKMRVINDT--------------ANRMSDIINIIDSIAFQTNILALNAAVEAARAGEHGRGFAVVAGEVRQLAQKSASSASEIRNLIE--------------DSTSQTQEGMHLVEKASALINGMVDNVEEMDVILREIGQASREQTDGISQINSAIGLIDAATQQNSCLVEESVAAAASLNEQALHLKELVNVFRV 513
12 -49.400IDP95064 methyl-accepting chemotaxis protein, partial [Campylobacter jejuni] AGM39603 [Campylobacter jejuni]  ali follow..  22  2......................................................................................................................................................................................................................................................GSKINHSDLQKLEEENKNLTHKIEKFQSENLELKNKITSLEQAALESKLKTDLLNVLLTGVLKNITIIQGDMLENVNKAEVISSYSKTSLAEMDELNHIANSINASLRNITESANKTRDVAGTLHRSVDEITNVINLIKDVSDQTNLLALNAAIEAARAGEHGRGFAVVADEVRKLAEKTQKATTEVEMNINLLKQNANEMYTQSEQVEKISIDSNAHIMSFSEKFTHLVNEAHSTNSNAVGIASEAFVSLAKLDHIAFKLNGYKEIFSKSGKQLADHTS..................... 281
13 -46.600IDP01957 putative methyl-accepting chemotaxis protein [Salmonella typhimurium LT2] STM1657 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  24  3....................................................................................................................................................................RNISVRTCIILFMVCAFLLVDTLQIAFLHDLPILITCNIIYLISALLLWWYMTCYLVVPINTVKKSIEEVAAGNLSIHISEFGNNCAGRLIPGINSLSENISALVREIRSSSQTAMTLSEQLAARSLSLSVKTEQQSASLIQTAASIDEMAASTKNNADNTRMASIQADCATQCARKGGELMVRVTENMRSITDC--------------ASQMTEIISLIDGIAFQTNILALNAAVEAARAGDHGKGFSVVAGEVRNLAHRSAEAAKSIKALID--------------VTHDNVRQGAAIVQEAEKNMQEIVGGSGQLNVLMSEISTTTREQEKGINQITLALSDLESATHSNVLMVEALSASSDVLKAQVIELQTKTDKFRL 357
14 -39.600IDP01046 putative methyl-accepting chemotaxis protein STM3138 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  12  1.....................................................................................................................................................................................................................................................................MFKKVLGLRHWNNNVVKIPPPAAESGANASDVVVDTPELCQKILMGISTIDIIRNAIIKSCEQLNIEKERINELNEQNDKARSSLKSLVEFITEIGTTSSDIGCRMGDLNTSLTQINACIKEIQKIANQTNLIAINSAIEAARVGDAGRGFSVISKEVKNLSEDVKHSSKSVSTLTSVIKDNTARVSEVLDNQQPVIDNITTNINQIVESIGIVIDKSLSMKSVMQYISTVQFLNIVKVDHVIWKMEVYKLLLNKDINSKITMHDQCR.................. 273
15 -35.000IDP91610 gene: ECs4554; EspB protein [Escherichia coli O157:H7 str. Sakai] BAB37977 [Escherichia coli O157:H7 str. Sakai]  ali follow..  10  29..........................................................................................................................................................................................................................................SALSIDSSLLTDGKVDICKLMLEIQKLLGKMVTLLQQQAVFESQNKAIEEKKAAATAALVGGIISSALGILGSFAAMNNAAKGAGEIAEKASSASSKAAGAASEVANKVKATESVADVAEEASSAMQKAMATTTKAASRASGVADDVAKASDFAEDLADAAEKTSRINKLLNSVDKLTNTTAVAVTSLAEGTKTLPTTISESVKSTHEVNEQRAKSLENFQQGNLELY--KQDVRRTQDDITTRLRDITSAVRDLLEVQNRMGQSGR.............................................. 309
16 -14.700IDP04182 sensor histidine kinase [Vibrio cholerae O1 biovar eltor str. N16961] VCA0238 [Vibrio cholerae O1 biovar El Tor str. N16961]  ali follow..  14  189...................................................................................................................................................................................TSRYEEAALDALSNVRSVITSLAVFGMVSGALLGVWLLRTLSKPLAELVKSTTALEQGRLDHRISISGPDELKTLARHFNYMAQSLEQAQQKERMSRQLIEREVADRTQELAQALQTLEKKHQQKEFFANVSHELRSPATAILGEAQITLRSRHNSDDEYRQTLLRISESAEQLAFRIEDLLMLIRH-RLFHPALTEL-LLGEIWQAVVRQASLLTHAQQVELT-----------TPAQGEWQTQLCYTDCDKLLMVIRILVDNA------LRYDPTQQPIGLNLELDEEAWRVQLVDQ----------IGIAEADLSVIFERYFR----AENGKRYRPDGLGIGLTLAQSIVKQ............. 516
17 -14.700IDP04672 sensor histidine kinase [Bacillus anthracis str. `Ames Ancestor`] GBAA1482 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  13  268...................................................................................................................................................................................AIASLQPVNEAMLVLKDYYVYALIIVFLVIILLSFYYSKIIVKPLIKINRVTKKMANFDFSEKLPVTADDEIGGLSGSINTLSVNLKDRIDRLNVANTKLQQDIERERQL----------EKTRKEFISGVSHELKTPLSVIRSFAEGIKDGVSKDTTY-----DVILEETENMNRLIVEMLE----LAKLESGTYKLDSIGELIQQVYTKLLFSMEEKHLQVN---DVNSSIFVKANRSR------------IEQVVVNL---LSNAIRYTPEGEKIQVSVITMEDTVKIEIEN-EESLEKIWDRFYRLDASRSRHTGLGLSIVKNILDLHH................................... 578
18 -13.900IDP04691 sensory box histidine kinase [Bacillus anthracis str. `Ames Ancestor`] GBAA5067 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  12  292...................................................................................................................................................................................AMASLQPVDEAVQMVQDYYIYIIAFVVVLIFLASFYYSKQIAKPLLKINDTTKKIAHLDFTEQIPITSKDEIGDLSKNINTLSNKLNSHIGQLEQDIEKERKL-----------------EKTRKEFISGVSHELKTPLSIMKSCISILKDGV--AEHKKEYYFQAMEREVDKMDTLILDMLE----LAKFESGTYKMKYIDTVMEAICEHLSVEIEKKELRVHKHIGP----EVVANQGR------------IEQVIVNF---ITNAIRYTPNKEDIIISTIDEKDHIKVCIEN-EEQLDKIWDRFYRVDAARQRSTGLGLAISKNILELHD................................... 595
19 -13.900IDP04331 sensor histidine kinase [Clostridium perfringens ATCC 13124] CPF_2181 [Clostridium perfringens ATCC 13124]  ali follow..  10  167........................................................................................................................................................................................QAIEEASALIKDFYKYIILIVIVIGLILSYVFSNLISKPLVKLNKSAKKMSAMDFSEKCDIEREDEIGNLAKTLNFLSKNLSNALDDLKIKNKKLEEDIEKEREL----------EKLRKDFIAGASHELKTPIGIISGYAEGIKDGIVDHKDQGV---DIIIDEAEKMNKLVMDMLE----LSKLEAGKIDLHSLTELTEEVLVKNSVDINKNNLTVVKNYSPTEDLYVQGDDFK-----EQVLTNFVTNAIKYSEPNNQIIIDIKPVEEDKIYFSIENTGAPDSDINKIWTQFYRGDTSRNRGSRSTGLGLSIVKNL............................................ 472
20 -13.800IDP04495 sensory box sensor histidine kinase/response regulator [Vibrio cholerae O1 biovar eltor str. N16961] VC0622 [Vibrio cholerae O1 biovar El Tor str. N16961]  ali follow..  14  392........................................................................................................................................................................................KEAFARVRQLEKLFVFAMLTAIVLVVIASHYLSNFITSPLLKLTWAAERVSAGDLDAMINTERKDEIGRLAVSFERMQRSIREKISLIKSQNKELESNLLIIRKQNDELQL---ANKLKDEFLATTSHELRTPLHGMIGIAEALISGANPISAAHKYQLDIIISSGQRLATLVDDLLDYHKM--DIQRCAVDLSSATRLVLELSHHYNLIG-NA-IKYTSEGDTGQG--IPAEQLEHIASRYRQGAGSISRQLIELMHGTLYVSSQPMVGTASEEEIAQARLTELPHFQAPEVLDSELPEQSNLPENEHGPLLLVADDEPVNLRVLDSFLRLEGYRVHTAQDGHQVLEAIKREKPELV..... 817
21 -13.200IDP02181 two-component sensor/regulator [Yersinia pestis CO92] YPO0256 [Yersinia pestis CO92]  ali follow..  14  288..........................................................................................................................................................................................AWEALKPALYQLPFALAILLLLTSVLSLLLRYYLAIPLWNFINIIGATGPQAMEPRLPINRIDELGHIARAYNNLLDTLNEQYDTLEMKVKERTLALAEAKRAAEQAN------RRKSDHLTTISHEIRTPLNGALGAVELLQNTPLDAGQ----------------MRLAETAHQCSLSLLAI------INNLLDFSRIESGQMTLTALLPLLDHSQALSKSLALSLELDTLR------------LRQILVNL---LGNAVKFTPQGRIQLR-----VRRQNQTLC-------TVEDTG--CGIDVQHQQTIFQPFMQ--------TSDHEQGTGLGLAIADNLAKM............. 591
22 -12.900IDP01908 gene: ssrA; sensor kinase [Salmonella typhimurium LT2] STM1392 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  14  287...........................................................................................................................................................................................NRILKIILQQIPFTLTALVLMTSAFCWLLHRSLAKPLWRFVDVINKTATAPLSTRLPAQRLDELDSIAGAFNQLLDTLQVQYDNLENKVAERTQALNEAKKRAERAN------KRKSIHLTVISHELRTPMNGVLGAIELLQTTPLNIEQ----------------QGLADTARNCTLSLLAI------INNLLDFSRIESGHFTLTALLPLLDQGPAQSKKLSLRFHTDSIR------------LRQILVNL---LGNAVKFTETGGIRLTVKRHEEQ--------------LVSDSG--KGIEIQQQSQIFTAFYQ--------ADTNSQGTGIGLTIASSLAKM............. 589
23 -12.700IDP92066 gene: GAPDH2; apicoplast glyceraldehyde-3-phosphate dehydrogenase 2 [Toxoplasma gondii] ABO93620 [Toxoplasma gondii]  ali follow..  9  200.......................................................................................................................................................................................................................................DAASSGTCSESSDAAFAPEFSDLRDLFFGACDAT---------VSPDDLPSVPEALEKLAGLESDVQARGDQLDEKEKVVAEYLVAAQEAAVRHEEASRAFEDAKRNKK----------------ENLAAAAEKAALEAAAEYADLTTAAQLVTEEAEQESAKA------LADAVAAGDLRFAINQKIVNEAGPEARGKVPRALLAPK--------------HVRISDPAAGRVLKIFFHNNFAPFEDLPCAALHADAHLCRQHPRCVVQVEQSGDEVLQRCLLDEAYLALLTKTPDFCAAAPAEAETGLGNSAA. 469
24 -12.600IDP04012 gene: virJ; sensor histidine kinase [Clostridium perfringens ATCC 13124] CPF_2355 [Clostridium perfringens ATCC 13124]  ali follow..  15  163........................................................................................................................................................................................SKEYLELRDLMSNIKFIVSITFLLILIFTYFLFERIINPLNYIKNSFKRIGDGDFKINLKVNSKDEIGDLACGVNKMANKIEEQIEKINEEKEKVLTL-----------------EKTRTEFFNNITHELKTPLTNISGYAQIMSEEDFHDNDFRKFALERINKESKRMHELIVSLIEISKNKSDIEGGEIENVNLKTLIEDLCEDFKVKGDKQGICISNNLED---IEFMCRE------------DEIRRIIINLLDNA------IKYSIKGSEIEISLFKDKEEKHIEIEEGVEKIFEPFYRENTKKSRENGLGLYICSELVKKYG................................... 463
25 -12.500IDP04132 putative two-component system sensor kinase [Yersinia pestis CO92] YPO2997 [Yersinia pestis CO92]  ali follow..  17  156.........................................................................................................................................................................................................IWMGVLGGLFFSTLLAWNLTRPMRQLRVGFERVAQGDLSVRLLRRRHDELTEVARDFDSMAERLQALVSALHDVSHELRSPLARLQLAIGLAHQNPDNVDNALQRIEHESERLDKMIGELLALSRAENHSLADDDEYFD--QELVKVVVNDARYEAQLLEVAAQSEYTVKGNAELMRRAIE---------NIVR-NAKVTLSALDDQGPG--VEENKLSSIFDRVKSAMSGITHKVILAHGGQVEARNGEQGG............................................................................................. 437
26 -12.500IDP04438 gene: cpxA; two component sensor kinase [Yersinia pestis CO92] YPO0073 [Yersinia pestis CO92]  ali follow..  16  151........................................................................................................................................................................................SPQSDFINLMFDRPLLLLIATMLISAPLLLWLAWSLAKPARKLKNAADDVARGNLKQHPELSGPQEFLATGASFNQMISSLDRMVVAISDISHELRTPLTRLQLATALMRRR-HGEGKELERIEMEAQRLDSMINDLLVLSR--SQHKNELHREPIKADELWSDVLENAQFEAEQMGKTLVV--PLFCNPAALDSALE---------NIVR-NALTDEARSGGTGLGLAIVETAVSQHRGWVKAEDSPLGGLRLIVW.......................................................................................................... 450
27 -12.300IDP04694 gene: yycG; sensory box histidine kinase YycG [Bacillus anthracis str. `Ames Ancestor`] GBAA5714 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  15  172...................................................................................................................................................................................VVASMEDVYKQMKDINQIFATGTVIALLVTAVLGILLAQTITRPISDMRRQAIEMAKGNYSRKVKVHSHDEIGQLALSFNNLSKKLQQARSSTESERRKLSSVLSHMTDIATDRKGDIILLNDPAEKMLNVSRELDQSVLEVLGIQEEFTLDHLYEEPDSVLLDFSTRNEPYILR-----------SFSVIQKETGKANGLIAVLYDVTEQERI-------ERER-----REFANVSHELRT-------PLTTMRSYLEALTDGA--------QDPNIAPQFLTVIQEETERMIRLVNALLQLSKLDSTEHRLMKEWVDFTDFFNNIIDRFEMSKEQNVSFKRSFSKKSRFIDMDTDKITQVLYNI.. 506
28 -12.000IDP04189 sensor histidine kinase [Clostridium perfringens ATCC 13124] CPF_0225 [Clostridium perfringens ATCC 13124]  ali follow..  11  166........................................................................................................................................................................................TEAYEILRNTLTIFIISGLIAIVIAIFLINTFAKELVSPLMILKQKSKNISEGKFKEELHITSGDEVEDLANTFNIMSENLDKYINEIKSA------------------------KLHQKKFFDNVSHEFKTPLTAIIGFSEIIPKLNDK--EKIVQSSALIEKEGKRLLNLVEEI------LAKSNKNTFEIEDVKSLIEDCLKILKIKLDNYDIKVYRNYES---FFIYGDHDKNIIDNAIKYSGCETLSISTKRSPNKMEVIIEDDGTGFIIKDEYVNPKGNGLGIKICKDIMQSQNYGFNIESELDVGTKVTLSF............................................ 461
29 -12.000IDP04664 sensor histidine kinase/response regulator [Bacillus anthracis str. `Ames Ancestor`] GBAA0996 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  11  1.MKSKAKFSIRYKIMAGYLVIILFLLISFIMLNNQISNLQKSRNFIIDHDFKVLNLTNQVEKDLLTIENKAKGFITSNNANQSLNSAERDYEKHYHDLFSLLEDNPSQQEKLKEINGNITNWMNKEIHPLIANHNSNKIQEID---------------TTEIQSLQSQLTDFRSTEEQLTKKRAAQLDTKNNKLELWLYSLLFLLSCISIIVSLYISNSITKTIKNVIQAIKSISSKEITERIHVNTHDEIKDLAHTTNHLLDEISK-LQTEIAELILMYQGVSSIEMLGNKILSGI-IQKTQTSCGAFYVREEYEETVYYVKKASFADQGFDIGKQSIKMGEGFIGQSA---------LEKKSFILRDIPEEFRYVTTGL-LVIPVLFEDEVIAV---MELVSVTDISDLHQDLIQQTQTLLHESQAMTEELQVQSEELQTQAEELQMQAEELRTTNEQLESRTEEAEQKTADLQITKLELEEKASELLRSSKYKSEMSHELRTPLNSINHLSDDEIELATVIHSSGKDLLTL---INDILDLSKV 560
30 -12.000IDP06113 histidine kinase sensor protein [Helicobacter pylori J99] NP_222872 [Helicobacter pylori J99]  ali follow..  13  120..........................................................................................................................................................................................LYKDLHSVSYRNYFLAITVGLLLILFLFLFVLQSLLPLRELRSQVKRFAQGDKSVSCKSKQKDEIGDLANEFDNCIQKINAMNESLRSIMHELRTPITKGKILSS-----MLKEELSCKRFSSIFDHLNMLIEQFAR-------------EQLASKNYGSNKEKFLMSDLIDKIEKMLLIDEDIEADFELFAIAL---------KNMID-NA-IKYSDDKNKSKP---LKEDFEKYLQPYFKSSN------PSQAHGFGLGMYIIKNALEAMGLNLSYHYSNGRICFTIHNSFYDLEADNEELPPPRKFERGEGNEGNRK......................................... 437
31 -12.000IDP95472 sensor histidine kinase [Listeria monocytogenes 10403S] YP_005962624 [Listeria monocytogenes 10403S]  ali follow..  13  156........................................................................................................................................................................................SGTEQVIGTINRYMFYTILLSITVALILSAILSKLQVNRINKLRAATKDVIQGNYNARLKENNFDEIGALAIDFNKMTQTLETSQEEIE------------------------RQEKRRRQFIADVSHEMRTPLTTISGLTEGLVNDIIP-KSETDRCIALIDTEARRLTKLVNENLD----YEKIRSNKIKLQNGKEFLELIKEQLDYVASEKGNTIT---AIDKDMAIYADYDRNIVKNSVQFTENGQITLTGTQDYKESVLTITDTGI-KADMSRTNTAFGESGIGSIVKQLIEYHDGSITVTSEPNKGTSFTIRL............................................ 468
32 -11.800IDP04673 gene: resE; sensor histidine kinase ResE [Bacillus anthracis str. `Ames Ancestor`] GBAA1498 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  13  158...................................................................................................................................................................................VYESLQVPIQGMERTTDFIFLSAGIAIILTTFFAFFLSTRITAPLRKMREVAFEVSRGKFDAKAPMVSQDEIGELATALNQMGKQLKFNM-------NALQQEKEQLASILSSMADGV-----NQEGEVVVINPPAEHFLQVWQEEKEIELSKKLPSELVELFHLVVESEQQQVVGINLQKGNYVVLMTPLYNQTKIRGAVA-VLRDMTEERRL-------EKMR-----QDFANVSHELRT---------------MVMLQGYSEAILDDIVQTKEEINEFVQIIYDESVRLGKLVNELLDLARMESGNVELHIGEVDIHPFVEKIGRKFQGIAKDTVDFKDSIEQYPFDADRMEQVLTNLIDN... 492
33 -11.800IDP04247 sensor histidine kinase [Clostridium perfringens ATCC 13124] CPF_1402 [Clostridium perfringens ATCC 13124]  ali follow..  13  161........................................................................................................................................................................................NPKIGFKIFVYIMISLYIFIFTMSLILYSKLTSKTFTKPLDKLMNGVRKLSLGDYSTRINIEKNNEFEELGEAFNNMASKIEEEKKLVRNIAHDLKTPLSSIIGYSNIIKNNPDIEKESLHKYISVIENNGERANEMIMELFEFYTLQSSEFILHKKYQDLSEFLRNLIADYIYLLEEKDFDFD-LEFDNKRLERAI---------GNLII-NSKFLISLKKEGDKVKIIVSDDGIGLSE------EIKKHIFNPFVREEKS----------------RNSKKGGSGLGTISKEIVEKHGGTIYLSDGPLKGCNFVIEL............................................ 475
34 -11.700IDP01736 sensor histidine kinase [Bacillus anthracis str. `Ames Ancestor`] GBAA5503 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  12  154........................................................................................................................................................................................TGEKEVLTNVGWTFLMTSLCLVAAGIFFAIRLAKSLHKPIDQLRQMAHRLANGDYKSKIELNEYVEIAQLSASFNAMADGIELHIKQLK------------------------EEKEKQKDFLDRITHELKTPLTAIIGYVDLIPKL--KAKEDVKESLRYVAVESERLLSLVEELLKSSKYGTSTFEISPTVVNIKELAEEAVSIVKPRLQKFEIEVINELTD----HVVADFDKNVLDNAIKYSDATQIRMNVIVNEREAKVFVHDDGIGIDEGVLAEWSSYGHGYGYICQEIMDKQGGSMRIESSEEIGTTIFITF............................................ 460
35 -11.700IDP04430 sensor histidine kinase [Bacillus anthracis str. `Ames Ancestor`] GBAA4921 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  12  175......................................................................................................................................................................................................VSLLLLAILLIGLLSYLVSRSVIKPIFVLKDATGKIKEGNLDFHIPVTSHDEIGQLNQGFEEMRKKLKESIEMQTQY------------------------EENRKELISNISHDLKTPITSIIGYVEGIKDGVANTPEKMDKYLTTIHTKARHMDTLIDELFLFSKLLNRVPFQFETV-ELNMFMQELIEEMQMDLSKEGIEVN-TADCEKINRVISNLIHNSVKYMDKEEKKIT--VTVSSDNNKVIVKVMDNGSGIESDTLPYISTGGSGLGAIAKQIIEEHGGNIWAESELGEGTSIFFSL............................................ 476
36 -11.700IDP02394 gene: phoQ; sensor protein PhoQ [Yersinia pestis CO92] YPO1633 [Yersinia pestis CO92]  ali follow..  16  174...................................................................................................................................................................................VVDTIPQELQRTDLVWNWFSYVLLANLLLVIPLLWLAAYWSLRPIKALASQISQLEKGERE-QLDENPPRELQSLVRNLNILLMNERQRYTKLADLTHSLKTPLAVLQTTLRSLRTGKQTTIEEVPIMLEQISRISQQIGYYLHRASMRSEHNVLGREIHS--PALLDSLYSALNKVYQRLTLDISPEVTFLGEKNDFMEVMG---------NVL--NACVDTLRPG-QGLGLSIAAEIIEQYQGKISITESPLGGARMMVT.......................................................................................................... 474
37 -11.400IDP04241 sensor histidine kinase [Clostridium perfringens ATCC 13124] CPF_1112 [Clostridium perfringens ATCC 13124]  ali follow..  11  274........................................................................................................................................................................................KKITEELIPIIGSTLLIVIFCLIVVVILINILSKALSRRILLLKDKAEDVSKGNFNNPIFTEDTDEIGIVTNSFGHMTRDLNDMINKV---------------------KIELEKKATELKALQAMINPLYNSLSTIKWKAIR-------------EGNDDISDITGYLAKFYRTSLNNGQDITDVKSEIDNIKSYIEIQKRIDEKG--FILQPIVENA---------------KHGIDCNQGKERGKII--VEFQEDEDSLIFKIYNSSNNNDINSIEEKPGKGYGIYNVKERIELYIECNLECSLVENNYICIALRL............................................ 566
38 -11.400IDP04515 putative sensor histidine kinase [Clostridium perfringens ATCC 13124] CPF_2673 [Clostridium perfringens ATCC 13124]  ali follow..  13  276......................................................................................................................................................................................................NRYLWIIPIVLVIHFIVKFIRKYDGLDTVIKGIEKVKKGDTDIEIKDNDDRQIRELADDVNDLRLGYKELVEE------------------------GIKNEKLKTELISNVSHDLKTPLTSIINYV-NILQLNNIKEEERKEYIEILDKKSQTLKKLIDDLFEVSKMSSELFKYNIDIIQLVQCIAEVEDVYSEKEIEFKINGPEE------CMVKIDPQRMTTNALKYSLEKTRVYVEIKDLENYVEISFKNISSYALDFDEKDSTIEGSGLGAIAKTIVELHNGKFRVECEGD..................................................... 565
39 -11.400IDP04484 gene: barA; two-component regulatory protein [Yersinia pestis CO92] YPO3381 [Yersinia pestis CO92]  ali follow..  14  166........................................................................................................................................................................................QSVRLKQYKEIFISTLLLLFCMCVAILFAYRLMRDVTGPIRNMVNTVDRIRRGQLDSRVEGHMLGELDILKNGINSMAMSLAAYHEEMQQNIDQATSDLRETLEQMEIQNVELGLAKKRAQEASRIKSEFLANMSHELRTPLNG---------------------VIGFTRQTLKTSLTPTQTDYLQTIQRSANNLLCIINDVLDFSKLEADKLILEAHTAHEKGLELTVLGDAMR------------LQQIVTNL---LGNAIKFTEEGNIDILVVVKAIASQQVTLM-------EIHDTG--IGISESQQAQLFQAFRQ----ADASTSRRHGGTGLGLVITERLVKE............. 494
40 -11.300IDP04007 sensor histidine kinase [Vibrio cholerae O1 biovar eltor str. N16961] VC1319 [Vibrio cholerae O1 biovar El Tor str. N16961]  ali follow..  12  133...............................................................................................................................................................................................QAIDRADNLLFVFMLGGFALYCMFLIWFLSRRLRELERVTHDFANGNLQARASTKSSKSVGKLNHSFNMMADKISHLILSTNAIAHDLRTPIFRIQWQAEVLAESQAKQQQQVASIIEDTEEMETMVDELLYYA-KLEHPESDIQSQYLEVNQWLADFIDEQSHLDADPQLLTRALVNLIRNAEKYAAIHDNGPGIEEQPHIFDAFYSTDSSRQSGFGLGLAIVKQIMARHQGEVTLTKSP................................................................................................................... 416
41 -11.300IDP04191 sensor histidine kinase [Clostridium perfringens ATCC 13124] CPF_0554 [Clostridium perfringens ATCC 13124]  ali follow..  13  291........................................................................................................................................................................................DFINADIQSLRKEMTIIGLLFTLVVLIFSYFLYSSIKVPLYNLLNKMKRVSEGDLKVLVNDTYEDEIGVISDNFDSMLKRVNELIEKT---------------------LQEVEKRDLEIRMLQAQINPLFNTLNSLKWTALM-------------NQDYTVSEGLSSLAELLRNTIIDKNELVTIREELENIKNYVVIQKEVDELL--FILQPIVENS------HGI------------DENKENQKII--IKIMSEEENILISIKDNGKGFNSKEKVKDNKSGIGWNNVDERIKLTLGYGTTIYSEVNKGTIVKIVIPKSI........................................ 583
42 -11.200IDP04343 two-component system sensor kinase [Yersinia pestis CO92] YPO2916 [Yersinia pestis CO92]  ali follow..  13  18........SLRQLVLMAFLLVLLPLLVLAYQAYQSLDHLSTQAADINRTTLADARRSEAMTSVALEMRSYRQYCVLDDATLATLYQHQRKQYTQMLVAHAPILPDARYYQTLQGLLNQLTDI-------------------------KCKNSGPDKEASILLEQFSRSNAEMVQATRDVIFSRGQQLQKDIAERGQFFGWQSLLLFLVSVLLVVLFTRMIIGPVKGIERMINRLGEGSLGNTALFKGPRELRSLAQRIIWLSERLAWLESQLRHISHELKTPLASMREGTELLADEVQDQQEVVAILDHSSRHLQQLIEQLLD---NRKLADGPGEPEHVDLAEMVGNVISAHSLPARAKMIRTET--ICWAEPTLLMRVL---------DNLYS-NATIWICSRQVNDRVQIDVANTGAPIPT------SEEIMIFEPFFQGSHQRKGAVK----------------GSGLGSIAQDCIRRMQGDLQLVTVDYAAVCFRIEL............................................ 476
43 -11.200IDP04428 gene: phoR; sensory box histidine kinase PhoR [Bacillus anthracis str. `Ames Ancestor`] GBAA4832 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  13  152........................................................................................................................................................................................EPLKDVHQKTWGLLIIGFVIACLVVVFLGMKITGQYIRPIESVTKVAIELAKGNYKARAYESHSDETGMLSKAINILARNLQEMTLEQEMQQDRLHTLIENMGSILIDSRGYINLVNRSYKETFHVTDELDRLYYESFHHTE----------------IELVEEIFMTEVKVRKQMLLPLGIGAPIIGTNHEWKGIVLVFHDITELKKL-------EQMR-----KDFANVSHELKT-------PITSIKGFSETLLDGA--------DNKKFCEHFLHIILKESERMQGLIEDLLDLSKIEQQGFKLSMGTVDMKGLLEDIHMVLDNKAGEKEISLQVNTLKRVSVIGDPSRLQQIFINL.. 484
44 -11.200IDP04165 sensor histidine kinase [Vibrio cholerae O1 biovar eltor str. N16961] VC1521 [Vibrio cholerae O1 biovar El Tor str. N16961]  ali follow..  11  309........................................................................................................................................................................................WPFLKAYVTNILEVGIITLFLLVISGLFVYRGSRDLFRPIERIHRVVKMVQLGKNIGQIGLDDKHELAQLAKQFDNMLDQLQQRNEEIVQAAHELEAKVQSRTASLQEKTAQLEHHIALLNQTRNKLVV----HEKLAALGELTAGIAHEINNPTA----ILGNTELIRFELGADASRVEEEIDAILLQIERIRNITRSLLQYSRQGGVQHVNPIIDES--------ITLVKTGSKK-HNSVEVNRHQLLQILVNL---QMNAIHAMNGKGRITIRSEDWVEEGQNRGAVI-----HIEDQGCGIKTTKREGTGLGLSVSQSLLS-GEIKVQSELGVGSTFSIFLPSKNEAKLRETLLLQ... 677
45 -11.200IDP04543 sensor histidine kinase/response regulator [Vibrio cholerae O1 biovar El Tor str. N16961] VC2453 [Vibrio cholerae O1 biovar El Tor str. N16961]  ali follow..  13  165........................................................................................................................................................................................SSLRLQQYQEIFSAGLVLVIGILLSGVFASRLMYDVTRPITHMKNMVDRIRRGHLDVRIEGKMHGELDTLKKGINAMAVSLSEYHVEMQHSIDQATSDLRETLEQLEIQNVELDIAKKRAQEAARVKSEFLANMSHELRTPLNG---------------------VIGFTRQMLKTQLTNSQADYLQTIEKSANNLLTIINDILDFSKLEAGKLALEATSAHEKGLEITVVGDPLR------------IQQVLTNL---VGNSIKFTERGNIDVSVEMRALRDDVIDLQ-------MVRDTG--IGISERQQAQLFQAFSQ----ADASISRRYGGTGLGLVITQKLVSH............. 493
46 -11.200IDP04104 gene: rstB; two-component regulatory system, sensor kinase protein [Yersinia pestis CO92] YPO2309 [Yersinia pestis CO92]  ali follow..  12  123...............................................................................................................................................................................................HQMRLLDLALLILIGLSLALPVFLWMRPHWKDLLKLENAAQRLGSGHLDERTHFDPTSSLSRLGVAFNQMADNINTLIVSIDGIAHELRTPLVRLRYRLAMSDNLTESEQQALHHDIGQLEALIDELLTYARLDRPQVSLNLEPIDLPAWLTTKIMDIRSIHQEREIELDIPHRGD-FGAVDLRLMERVL---------DNLVN-NALLDPSRTGGCGLGLAIVHSIALAYQGSISVNTSPLGGASFRFS.......................................................................................................... 411
47 -11.200IDP95462 sensor histidine kinase [Staphylococcus aureus subsp. aureus USA300_FPR3757] YP_494944 [Staphylococcus aureus subsp. aureus USA300_FPR3757]  ali follow..  14  153........................................................................................................................................................................................PDIGETFSEFRTFLAVLLMLLLFISISLVIASTYSIIRPVKKLKLATERLIDGDFETPIKQTRKDEIGTLQYHFNKMRESLGQV---VQNVSHEIKTPLTHIHHLLSELQQTSDKTLRQINDIYTITTQLSGLTTEL--LLSELDNHQHLLFDDKIQVNQLIKDIIRHEQFAADEKSLIILA--NFLGNQRLLHQAL---------SNLLI-NAAIDIALQHSHNNIIFTISNDGSPISP------QAEARLFERFYKVSKH--------------------DNSNGLGAITKSIIELHHGTIQFTQSNEYVTTFTITLPNN......................................... 455
48 -11.100IDP04463 gene: narR; nitrate/nitrite sensor protein [Yersinia pestis CO92] YPO1959 [Yersinia pestis CO92]  ali follow..  10  118..................................................................................................................................................................DEVAASVADFVHQLDALVLAIDHKTEQRLLQVTLIPLVFSLLTLSLLLAMIYYLRRRLLRPWLKLISMANAIGRGDFSQRYTLDQRDEMGMLGTALNRMSQELSDLEQRVVNKTADLQQKNQVLAFLYHSSRQLHTHQPLSIEQLQALTTLENVQICLYENHLYRDHVNHNADAEYLMPKNRPASLTISGPVRPISHPELWQSLSWSLSDKLGQYGLLQQLVDMLVEQ-----LTSTLALESQAKHQQ--LLLMEERSAIARELHDSIAQISCLQMQTPDLPENSNLLIKQMRDELNIAYRQLRELEAALQALVNEFSERAGLSITFKYQLPPDQ-VPNHQAIHMVNIVREALNNIYKHARASEATVNVHLEQGDVVMSIT.... 537
49 -11.000IDP04659 sensor histidine kinase [Bacillus anthracis str. `Ames Ancestor`] GBAA0272 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  15  184.........................................................................................................................................................................................IPDGVVMYDTQEGPFPFLIGVLVFIFSFFYITKRKMKQIEAMAEGVKEIEKGNLAYRIEKKGEDEIASLTENINNMAEELMNNIEK------------------------ERKLEKQKNELITNVSHDLRTPLTSIMGYLRLLRDSKYENKEQHDEYTRIAFAKSEQLKNLIEDLFEYTKL--VLEKQEVCVNELLE-LVPQAEEHGLFVKKFPEERAYAAIDSEKMVRVFDNLLMNAIKYSKDDGEIK--VSLQRQRWEIQIVIANHSEEFTREELASRVTEGSGLGAIAKSIVELQGGSIRAEYKDG..................................................... 488
50 -11.000IDP04352 sensor histidine kinase [Bacillus anthracis str. `Ames Ancestor`] GBAA0584 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  13  179........................................................................................................................................................................................SFLENMLLKLMKQFLIISVLTIILTTISVFIFSRVITEPLIKMKRATEKMSKLNKPIQLGIKRNDELGSLAKTIEDLSSELTYM---LASVAHELLTPLTYMKGYAKVAKRDSEEREEYLQIIEDETDSVTDLVQDL--MLVQLEQHQFVIKKQKVLLRPFLERMVEKTKTTLTNLHVYCKDDLEVCIDERRMEQVM---------LNLLH-NATITIRVLAETNSFTISVQDEGEGIPE------GDIPHIFDRFYR--------VDKSRTR--------ATGGKGIGAVAKEIVELHNGSILVTSKLDVGTNFIIEL............................................ 484
51 -10.800IDP04347 sensor histidine kinase [Clostridium perfringens ATCC 13124] CPF_2345 [Clostridium perfringens ATCC 13124]  ali follow..  10  276........................................................................................................................................................................................SNATKVPLLFKVSAFLVSLFLFIIAECVLYIKFKNLSSRMDSLVLAMEKVEKGDIDVHIPLKDRDEITFIADNFNKMCEKLNDHIRKS---------------------LAELRQREAEIVALQNQINPLYNTLESIRMKAIC-------------NGDKEVGKMLYSLAFLFRSQVKGNLIV-SIDQEIKYCNKYLELFKECEEDL--FTLQPLIENY------HGIRLERDD--ELKIYIYKHLEDIVVEVI--DNGRGIPKEKLDDINRRIRECDHSGKSIG--MLNVHERIKIKEPYGLTVTSEENKGTNMILKF............................................ 572
52 -10.600IDP04667 sensor histidine kinase [Bacillus anthracis str. `Ames Ancestor`] GBAA1313 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  11  152........................................................................................................................................................................................KSIKDLIYDMGLILAPLALAITLLTIWIGRKIIIAITRPLSQMERVANHLATGDFSERITISSEDEIGRLGKAFNKMANSLETEDVKLANVSHELRTPLSYIKGYSEAILDGVPQQEKVTQLIHKEADRMQRLVHDL--DLAQLEGEHFPLQKQPIVFSQLIEDVLDTYEIKFIEISTNLNPEIIVMIDEDRMQQVL---------HNVLD-NADIMITLRQIDDYCELSIKDTGIGIDT------EHLENLGERFYRVDKA------RSRQHGGTGLGLA---------IVRQIVHIHDGQWQIESEKGNGTTVSIKL............................................ 457
53 -10.600IDP92003 sensor histidine kinase [Streptococcus pneumoniae str. Canada MDR_19A] SpneCM_010100002775 [Streptococcus pneumoniae str. Canada MDR_19A]  ali follow..  14  39.....................................................................................................................................................................................................LLGMTIVASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEMSHDLQVSFDSIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLATIGRQLNKLVEELNFTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERQVIPESARIEGDYAKLSRIL---------VNLVD-NAFKYSAPGTDEGQGIA--VETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLGST........................................................................................... 336
54 -10.600IDP04397 sensor histidine kinase [Bacillus anthracis str. `Ames Ancestor`] GBAA3230 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  12  141........................................................................................................................................................................................SRLSSTMNTLIVLTLISFPLLILIAAVGGYFITQRAFRPVQQMSDSASKIGDGDLSKRINLKGKDEMYHLAQTFDKMFERLETSFESTSDASHELRTPTSVIISQCESQRNNPKEMEESLEVILKQSRKMSALISQLLLLARADQGNDNTFQFECINMSELTEIVVEELSLMVQEITTHIEEDLFIKADQTLMMRLL---------MNLLT-NATVHMQLFRDETNIIGKVSDNGIGISE------QHITKIWDRF----------------RVDAARTSSNIGNTGLGSMVKWIVELHGGEITVESGLGEGSTFTFKL............................................ 451
55 -10.500IDP04550 sensor histidine kinase [Clostridium perfringens ATCC 13124] CPF_0460 [Clostridium perfringens ATCC 13124]  ali follow..  13  446......................................................................................................................................................................................................IFGVVIYSGILFYFGRKYIDKWKKDYNKILEKTKEISNGNLDSKDDE-DCGFFNPMRDELNNIQKGFKAAVDE------------------------EVKSQRMKTELISNVSHDLKTPLTSIIAYVDLLKG--EEDEEKRKAYLETLERKSQRLKHLIEDLFEVSKATTNLNIMDVDISYLMQVVLELDDKENLIVVKYALPNSRV-KEGRENVDVI--IKNISA--DEITFNINEISDRFVRG--------DKSRNTEGSGLGLA---------IVKSFVELQGGKFHIEVDGD..................................................... 732
56 -10.400IDP04662 sensor histidine kinase [Bacillus anthracis str. `Ames Ancestor`] GBAA0650 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  14  148........................................................................................................................................................................................ESIEKLVNGLTKQFIIAGAITFLLTVITIFLLSRLLTKPLLHMKHATEKMSKGDLSVSLTTTRNDEIGELSSSIQTLANDLHYMKTELASVAHELRTPLTYVRGYADIALKETTSPEQRLRYLSIIKDEITNLVQDL--SLAQMEQHNFSIQVKEVHLHTFLTRISEKVNAMYKEVSFSCPPTLLVNLDEQRFEQVV---------VNILN-NAQIHISVIEENKRISITMEDEGEGIPP------EDLPHIFERFYRVDKA------RSRATGGTGLGLS---------IVKEIVELHGGNITVTSEVDHGSCFTISL............................................ 453
57 -10.300IDP04302 sensor histidine kinase [Clostridium perfringens ATCC 13124] CPF_2503 [Clostridium perfringens ATCC 13124]  ali follow..  14  156........................................................................................................................................................................................RNVDNFILNFFLVFLVIGLTVLAIGIILSYFLANSIVNPITELIKVSEQMAKGNLKVRNKIVTNDEIEKLADSLNIMAEEIENR---ISSVSHELRTPLTSIKGWAITLNNDFETLKMGFDIIEKEADRLSNMVEEL--DFSKFVSGKIKLKYEEINLKEFIEYLRLYMNPRAEREHKGITEDFIIVGDKDRLKQVF---------INII--NAFKFTHENEDTGCG--ISKEELPRVKEKFYKGKNSICDEIIALHEGTLEIYSELGKGTK........................................................................................... 453
58 -10.100IDP91681 LAMC3_HUMAN [Homo sapiens]  ali follow..  11 1094.....................................................................................................................................LQRLNKGARCAQAGSQKTCTQLADLEAVLESSEEEILHAAAILASLEIPQEGPSQPTKWSHLATEARALARSHRDTATKIAATAWRALLASNTSYALLWNLLEGRVALETQRDLEDRYQEVQAAQKALRTAVAEVLPEAESVLATVQQVAEDLGLKAKALEKTVASWQHMATEAARTLQTAAQATLRQTEPLTAALTQASSSVQAATVTVMGARTLLADLEGMKLQFPRPKDQAALQRKADSVSDRLLADTRKKTKQAERMLGNAAPLSSSAKKKGREAEVLAKDSAKLAKALLRERKQAHRRASRLTSQTQATLQQASQQVLASEARRQELEEAERVGAGLSEMEQQIRESRISLEKDIETLSELLARLGNETQWALERLRLQLGSPGSLQRKLSLLEQESQQQELQIQGFE. 1559
59 -10.100IDP04692 sensor histidine kinase [Bacillus anthracis str. `Ames Ancestor`] GBAA5105 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  13  61.....................................................................................................................................................................................................INFFLIFFIPLSIIFFFFLTKPYLKYFSEISNGIHHLANGNFTNRVQVSSNDEFGDIAREINVASEKLKEAVERGDFA------------------------ESSKDQLVVNLAHDLRTPLTSVLGYLDLILKDENLTKEQIKHFSTIAYTKSQRLESLIDELFEITRMYGMLQLNKKPI-DISELLIQLDEELYPLLEKHHLEAR---NVDPHLPINGDGKL---------ARVFENLLTNAVRYGYDGQFVDLNGYIDNEEVVVQVMNYGDSIPE--EDLPYLFDMFYTGDKSRTENTGLGLFIAKNIVEQHNGTISAESNVVRTI...................... 355
60 -10.000IDP04158 sensor histidine kinase [Vibrio cholerae O1 biovar eltor str. N16961] VC1088 [Vibrio cholerae O1 biovar El Tor str. N16961]  ali follow..  12  141........................................................................................................................................................................................SYLEQQLAHARKWTLLIVLGEMGLVALFSYLLGNALTRRLTELKTATDQITFGNREVLLEIQGHDEISRVAHSFQQMVQSLRHSEATMRDYQHQLEQWNLELEDKVNQRTETLLAKNQQLEE---MNTKLTLMKDKLVETEKMISTLAAGFAHEINNPNGALKSHLQLLQQDFNQLKVGFEQIDILLSGSDFHGKFTQTKNALYLEESFSGIEESLRDALHCVD---IKTIVDKVQRCQAEPALHDSSWVSPLSLVEQAIQICGLREWVVWKEQTLYPPLIYCYSNDFVTANNAYQAYASDDIELSLRHDHQQLMSIEEKQHAFDPFFTTHDVGKGVGLGLTEAYSSIK.............. 505
61 -9.950IDP04542 putative two-component system sensor protein [Yersinia pestis CO92] YPO2000 [Yersinia pestis CO92]  ali follow..  12  148...................................................................................................................................................................................VAIDSTPYMGTLNEFTRTLIVITAIGVLFVALLGFVIARIGMRPVNKLSEQAQHLAPGNHGQRLDTLTPDELQKLAVAFNGVLERQEIAWRQLADVAHELRTPLTNLMGQTQLGLSRKRETHELEDLLESNLEEMTSIVNDM---LSHAQAGEHATQLTDVSLREETYKTTEYVEPSFAELSIHVEGDITARIDRRLFHRSL---------ANLLE-NSARHAVTGTTANIGAPIAAEHLRVDSSRARSDTHSIVRAVAIMHRGDVFASSQNGINT............................................................................................ 451
62 -9.930IDP04272 lantibiotic biosynthesis sensor histidine kinase, putative [Bacillus anthracis str. `Ames Ancestor`] GBAA3899 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  11  154......................................................................................................................................................................................................VLFILLFVAEVIFLSRSFGKSLSKEMMILRKVTDKIQKEDLDFQVEQSKIKEVNEVLTSLVKMKDELNHSLRTQ-------------------------NMETNRREQIAALAHDIKTPLTILRGNAELLNESM--LDSNQKKCNEHILKSIDEMEIYMKSLLDITKCEEGAPLQFMQT-DLRDFIHNIIEEMNIMM-NAIEYSPTKGDSGRGF----------------TEEEMHSATEQF----------------RGDKSRNAKDHHGMGL-YIAKSFAKQHGGNLYLSNSEKLHGA................................................. 445
63 -9.860IDP04258 sensory box histidine kinase [Clostridium perfringens ATCC 13124] CPF_2010 [Clostridium perfringens ATCC 13124]  ali follow..  13  148........................................................................................................................................................................................ENAKILDSINSNYLLVGVILSLVIALLLTVKITNIILNPLKELEQLTSTIASGNFHKRVKINSKDEIQRLGKSFNYMAEQLEITMERFKDKQNGLEAILKSMGS--------AFDRDMNVLMINPYAKKIFGISGEIIGNKLLDYITDKEVLKAFFDEKDRVEIEVN----YNDDPKILKIRKASIINEPEIIGTVV-VIQDITDIKKLFVANISHELKTPLTSIKGFAETDETRNKFLSIIDEESDRLARLLEDI------CLYEIEQKRSTVLEEFNVDEEIEKVYMLLNDQAK---KKGVEIFLDTNSNCVLMGDKDKFKQMLLNLVSNSVKYTEKGGKVRVESYNRDMNLVLVIE.... 501
64 -9.830IDP04660 sensor histidine kinase, putative [Bacillus anthracis str. `Ames Ancestor`] GBAA0286 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  10  1.................................................................................................................................................................................................MDPKVKISLFITLILITMYLFFSRIQFIQNHKSIDTKLSRALKGNLQTRLFTSNDQSLHNIVFSINELITELEKVRIKLSSISHDIRTPLTSIIGYIDALKDGVAASEIEKQEYLKILYMKSNNLKHLVDEIFNMAKLDANEFPLKEEKLDFSEVTREVLIDFLPEISKHNIKLQPIIADHLSLMRII---------GNLMK-NATIGVELLETDAAYELLIWDKGPGIPK------HDLQNVFERMYRSEQS----------------RNSSFGGSGLGSISKALVEKNGGHIWVESIPWERTTFGFSI............................................ 306
65 -9.740IDP04419 sensor histidine kinase SrrB, putative [Bacillus anthracis str. `Ames Ancestor`] GBAA2861 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  13  151........................................................................................................................................................................................AHSNEIIKTLNSFYLFILVITIFLIIVLVWILSKTITTPLKELSDVAEDISRLQFK-KTKVKTNDEIGDLATSINIMSEKLQEAHQDLT------------------------DRNEHLKRFMGDVTHELKTPIALVKAYSMGIKDGLDDGT-------DTIIKQSDHISNLIEELLR----FSKLERDVLQKESIKSLVQSILDKHKIELESKEIN-LQVNYNVGDAIVYADVNKNLISNAIKYTSNQNIKITLEDRNESVYFQIQNGMNAEHMKDIDKIDRSGTGLGAIVKSIVERHGFDYGVVTIGG..................................................... 447
66 -9.720IDP04076 sensor histidine kinase [Bacillus anthracis str. `Ames Ancestor`] GBAA2213 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  13  140...................................................................................................................................................................................MTERLDSLQENLNMLKNVLVIASLLVLIPSFFAGRMLSKFILKPVNSLIQTMEHIQVRGIFKKIPLKSKDELHKMGSTFNKMIDLLHQNFEKVSDASHELRTPLTVIESYAKLLKRWGMKKQDVLEESVEAIYSEAVRMKGMTNQMLLLANSSADWSLETNE-VRLCQVTAEQLEKTYAR-QKIKQVLVVLLDNAMKYSSIQDYGMGIPKEQKVFDRFFRVDKARSGGTGLGLSIAKQIIDAHEGDIQLESEE................................................................................................................... 438
67 -9.700IDP04680 sensor histidine kinase, putative [Bacillus anthracis str. `Ames Ancestor`] GBAA3066 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  10  55.....................................................................................................................................................................................................MLIIFLLSLLVLAFVFSRSINTVLNKINILNQTIRDLADKKIPNIIDVKSDDEMGELIKSVNLLIERTTYRELELNKLRHDINTPLTAVRLQLYYLEGEYKGQAPVLESLYEQIQYISDLTNEFNMQSTETLENTYIVHDEVN--HNLIETMIKKWSYLYSIHKNPQDKELIWNSNELWIQRLFNIFQNVLKHSKAKKLKIIIDDINSKGTGLGLKNIEDISKTLQSNSEGTMFSFENTQKNI........................................................................................................... 333
68 -9.670IDP00013 LPXTG-motif cell wall anchor domain protein BA_3254 [Bacillus anthracis str. Ames]  ali follow..  10  42.....................................................................................................................................................................................................................................................EIKQHKQGLDAKLQQHKENVDQTLNELNKVKENVDTKVNELHERKQVADEKINEIKQHKQELDAKLQQDKQIAEDKIAEIKEHKKQVEDKVAEVKEHKQNIDNKVNEIKEHKQTVDEKVNEMKQKENIDQKVNELKEVKKQVDEKLAELKKAKQTAEDKLAELKENKPNTGNTLEEL----KKIKSNLDSLSANLELAKQDVKNKLAALQEARQDLINKINEIKQSKQTVSDDLSKKKQ---DLDIKINDFKHTEKKIDDKLAEIHTTKQNIDNKINEVSQSKQTETKTGTTNAN....... 330
69 -9.590IDP04665 sensor histidine kinase [Bacillus anthracis str. `Ames Ancestor`] GBAA1118 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  9  250..........................................................................................................................................................................................DDVFTKKFLIGCGLILLIVFVYLVILSIWYGNKFGKPLLHAMRWLKNIAGGKYEEPVSKKGKPIRFRKSGKEKWSFRLFSDVTNSLEHLSITLKKNDAMRQVL----------QQTREEWITGLTHDLKTPLSSIYGYALLLESKQYNTDRDIQQFGSVMKEKSQYMTTLIDDLSLTYQLKNNAQHVNIEMNQFVKVLLQFINNENLLV-NANVIVKLSQNATSFTLSISDNGKGM------DDKTKELLFERYYRGTN-----------------TEESNIGTGLGAITKQLVHAHNGAISIDSELGKGTTIILVF............................................ 576
70 -9.410IDP04358 gene: creC; putative histidine kinase sensor [Yersinia pestis CO92] YPO0895 [Yersinia pestis CO92]  ali follow..  12  171........................................................................................................................................................................................LSMVPVIKRSERKILFAGGLLLGIALLIGLGFVWWINRAIGKLVDYAERVAEGQAV-ALPAMGSSELNDLALALESMRLKLDGK---VHTLTHELKSPLAAISGAAELLRESPPPETAQLINIEQQSARIQQLVDKMLVQAR--LESRVDLQLSPLEISHILKQSFSAKEAQAVSLRLKSVDNAMLIGDGLLLSQAL---------NNLID-NAEISVSGERQDDTYLITVEDSGSGIPG------YAQEKIFDRFYS--------LPRANSVKSTGLGLN---------FVREVAAIHQGSICLENRLPQGVSARLTL............................................ 470
71 -9.380IDP04678 sensor histidine kinase [Bacillus anthracis str. `Ames Ancestor`] GBAA2560 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  14  80.....................................................................................................................................................................................................LFLFSIFSSYLYIFYRHERKLYYETCIKKMIEEIRYIANGNFNHKVSIVNHNYLEELASGVNQIVEQLKVSIDEERQA------------------------EQAKSELITNVSHDLRTPLTSIVGYVNLIHHDNYRDEVELRHYIQVIYDKVTRLNALMNDLFEYTRV-KELSLYSVPI-DIVELLGQLTVQFRIQLQEANID-CRPFFPSKKLMVLADG------------DKLVRVFENL------IINAIAYGNDGDYIDITAYENNNMIAIDITNDLPHIFERFYRVEKSRSTNSGLGLAIAKSIVELHK................................... 362
72 -9.360IDP91721 gene: MMRN2; multimerin-2 precursor [Homo sapiens] NP_079032 [Homo sapiens]  ali follow..  8  291...........................................................................................................................................................AKFEAKVQENTQRVGQLRQDVEDRLHAQHFTLHRSISE----------------------LQADVDTKLKRLHKAQEAPGTNLVLATPGAGARPEPDSLQARLGQLQRNLSELHMTTARREEELQYTLEDMRATLTRHVDEIKELYSESDETFDQISKVERQVEELQVNHTALRELRVILMEKSLIMEENKEEVERQLLELNLTLQHLQGGHADLIKNCQKLYLDLDVIRGQRDATRALETQVSLDRQLDGSSLQALQNAVDAVSLAVDAHKAEGERARAATSRLRSQVQALDDEVGALKAAAAEARHEVRQLHSAFAALLEDALRHEAVLAALFGEEVLEEMSEQTPGPLPLSYEQIRVALQDAASGLQEQALGWDELAARVTALEQASE. 670
73 -9.300IDP04304 sensor histidine kinase [Clostridium perfringens ATCC 13124] CPF_2640 [Clostridium perfringens ATCC 13124]  ali follow..  14  2........................................................................................................................................................................................QNELVFLDIVNKIILGIGVLLILASTIMGFIISRSITRPINKLMTKAKYISKGEYDKKIEINTDIEINDLINSINNLSQSIKEQ---TGDISHELKTPLTNIQSHLEAMIDGIWEPTEELLSVKEEAERLSSLVSDM-QKLNKYDESSIKLKKDNVNISDIICFVIFQFSNLAKSKNIKIEYEKKLYCDKDKITQAL---------VNILS-NAIRYSNEGSDQGIGIS--ADKSRTRATGGTGIGLTIVKSIVSSHGGEVKLESKLGEGSK........................................................................................... 300
74 -9.300IDP04148 gene: basS; two-component system sensor protein [Yersinia pestis CO92] YPO3508 [Yersinia pestis CO92]  ali follow..  14  45...................................................................................................................................................................................AKARNEQVDKEIAEAIASLLAPSLIMMTITLLLSFWAISWIIRPLDQLQQKLAERSADNLSPLVVNSEMQEIVSVTSTLNQLLLRLSNTIQQTADAAHELRT----LAGIRLHLELMEKQGIAESKSLINRIDLLMHTIEQLLMLSRAGQNFASGHYQTLDWVNDVVPPLQEELAEMCETIQWELPPHAKMEGDATLLRLML---------RNLV--NAQIIVTLSTENQGVLLQVTDEGPGIKQ------NQAGELTQAFRRMDQR--------------------YGGSGLGNIVIRIAQLHQGKLTLENRLDRTGLKAQ.............................................. 344
75 -9.230IDP04544 osmolarity sensor protein EnvZ [Vibrio cholerae O1 biovar El Tor str. N16961] VC2713 [Vibrio cholerae O1 biovar El Tor str. N16961]  ali follow..  16  157.........................................................................................................................................................................................................SIIMALLIVIGGWLFIRLQNRPLIALEKAAKMVGRGETPPHLPEQGTLEIRSVTRAFNRMSKGIQALEEDMAGISHDIRTPLTRIRLATEMMS---PEDSYLAESIISDTEECNQIISQFMDYLKPVNREAFEASSEGGYEVQIETELQAGLAPALGNPIAIKRSLSNLVVNALRYGNVEDNGPGIDPSNKVFEPFTRGDTARSEGTGLGLAIVKRIVSQHHGAVSVSNRSQGGLRAQIS.......................................................................................................... 430
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Friedberg I, Godzik A. Fragnostic: walking through protein structure space. Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W249-51.