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Query: IDP04225 gene: ipaB; IpaB, secreted by the Mxi-Spa secretion machinery, required for entry into epithelial cells [Shigella flexneri] CAC05803 [Shigella flexneri], from CSGID

Results of FFAS03 search in CSGID
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MHNVSTTTTGFPLAKILTSTELGDNTIQAANDAANKLFSLTIADLTANQNINTTNAHSTSNILIPELKAPKSLNASSQLTLLIGNLIQILGEKSLTALTNKITAWKSQQQARQQKNLEFSDKINTLLSETEGLTRDYEKQINKLKNADSKIKDLENKINQIQTRLSELDPESPEKKKLSREEIQLTIKKDAAVKDRTLIEQKTLSIHSKLTDKSMQLEKEIDSFSAFSNTASAEQLSTQQKSLTGLASVTQLMATFIQLVGKNNEESLKNDLALFQSLQESRKTEMERKSDEYAAEVRKAEELNRVMGCVGKILGALLTIVSVVAAAFSGGASLALAAVGLALMVTDAIVQAATGNSFMEQALNPIMKAVIEPLIKLLSDAFTKMLEGLGVDSKKAKMIGSILGAIAGALVLVAAVVLVATVGKQAAAKLAENIGKIIGKTLTDLIPKFLKNFSSQLDDLITNAVARLNKFLGAAGDEVISKQIISTHLNQAVLLGESVNSATQAGGSVASAVFQNSASTNLADLTLSKYQVEQLSKYISEAIEKFGQLQEVIADLLASMSNSQANRTDVAKAILQQTTALast
1 -117.000IDP04225 gene: ipaB; IpaB, secreted by the Mxi-Spa secretion machinery, required for entry into epithelial cells [Shigella flexneri] CAC05803 [Shigella flexneri]  ali  100  1MHNVSTTTTGFPLAKILTSTELGDNTIQAANDAANKLFSLTIADLTANQNINTTNAHSTSNILIPELKAPKSLNASSQLTLLIGNLIQILGEKSLTALTNKITAWKSQQQARQQKNLEFSDKINTLLSETEGLTRDYEKQINKLKNADSKIKDLENKINQIQTRLSELDPESPEKKKLSREEIQLTIKKDAAVKDRTLIEQKTLSIHSKLTDKSMQLEKEIDSFSAFSNTASAEQLSTQQKSLTGLASVTQLMATFIQLVGKNNEESLKNDLALFQSLQESRKTEMERKSDEYAAEVRKAEELNRVMGCVGKILGALLTIVSVVAAAFSGGASLALAAVGLALMVTDAIVQAATGNSFMEQALNPIMKAVIEPLIKLLSDAFTKMLEGLGVDSKKAKMIGSILGAIAGALVLVAAVVLVATVGKQAAAKLAENIGKIIGKTLTDLIPKFLKNFSSQLDDLITNAVARLNKFLGAAGDEVISKQIISTHLNQAVLLGESVNSATQAGGSVASAVFQNSASTNLADLTLSKYQVEQLSKYISEAIEKFGQLQEVIADLLASMSNSQANRTDVAKAILQQTTA 580
2 -53.300CPX_91673_04225 Complex of CD44_HUMAN with IPAB_SHIFL [Undefined organism]  ali follow..  100  744MHNVSTTTTGFPLAKILTSTELGDNTIQAANDAANKLFSLTIADLTANQNINTTNAHSTSNILIPELKAPKSLNASSQLTLLIGNLIQILGEKSLTALTNKITAWKSQQQARQQKNLEFSDKINTLLSETEGLTRDYEKQINKLKNADSKIKDLENKINQIQTRLSELDPESPEKKKLSREEIQLTIKKDAAVKDRTLIEQKTLSIHSKLTDKSMQLEKEIDSFSAFSNTASAEQLSTQQKSLTGLASVTQLMATFIQLVGKNNEESLKNDLALFQSLQESRKTEMERKSDEYAAEVRKAEELNRVMGCVGKILGALLTIVSVVAAAFSGGASLALAAVGLALMVTDAIVQAATGNSFMEQALNPIMKAVIEPLIKLLSDAFTKMLEGLGVDSKKAKMIGSILGAIAGALVLVAAVVLVATVGKQAAAKLAENIGKIIGKTLTDLIPKFLKNFSSQLDDLITNAVARLNKFLGAAGDEVISKQIISTHLNQAVLLGESVNSATQAGGSVASAVFQNSASTNLADLTLSKYQVEQLSKYISEAIEKFGQLQEVIADLLASMSNSQANRTDVAKAILQQTTA 1323
3 -19.100IDP04697 gene: yopB; secreted effector protein [Yersinia pestis CO92] YPCD1.29c [Yersinia pestis CO92]  ali follow..  18  109..............................................................................................................................................................................................................................................................ELGKLVSNLEEVRKDIKIADIQRLHEQNMKKIEENQEKIKETEENAKQVKKS-GIASKIFGWLSAIASVIV-----GAIMVASGVG-----------AVAGAMMVASGVIGMANMAVKQAAE--------------ISQEAMKILGPILTAIEVALTVVSTVMTFGGSALKCLANIGAKLGANTASLVAKGA-----EFSAKVAQISTGISNTVGSAVTKLGGS-FAGLTMSHAIRTGSQATQVAVGVGSGITQTINNKKQADLQHNNADLALNKADMAALQSIIDRLKEELSHLSESHQQVMELIFQMINAKGDMLHNLAGRPHT 400
4 -16.900IDP91310 putative translocator protein PopB [Vibrio parahaemolyticus RIMD 2210633] VP1657 [Vibrio parahaemolyticus RIMD 2210633]  ali follow..  16  117..............................................................................................................................................................................................................................................................ELAAITDKLKSAQNELKIQEVKVAKAKHEQEMAENQEKIKESEAAAKEAQKS-GLAAKIFGWISAVVSIVV-----GAIMVATGVG-ALMIAGGVMGAVS-------LQEPAVQDALKE------------------AGVNVDVLNKVVMALEIAVAVIGAIVTFGGAAAGGIAKLAAKSASKIAQKVTDIATK-AAANMAKVADMGSKAATTTAKA-----------------IRYGAETVDLTVNIGKGATDSVHAANNANVTEIQADITDLRAKMTLSQAVIDKLKEEIGKLMEDFQELMSIIMQMIQAKSETMQTVLSRPAT 398
5 -15.200IDP93853 secretion system effector protein SseC [Yersinia enterocolitica subsp. palearctica Y11] YP_006007025 [Yersinia enterocolitica subsp. palearctica Y11]  ali follow..  11  53................................................................................................................................................................................................................PQREAQSALDRLLGSLSHSGVGGDCGRLSLDNPGETDIQQIMSMVSSLLGLFSNLCKSISQQMERATDVQTFLRDKRVAEYQQQIDKAVEQADKAKK-AGIFTAVFDWIVGAVEVVYGAIASGVAYLAAGTGLVKAAAEEVIDVAGKVQLGCECFAMAIDIFQAARAINAARTVTKGASEV-LKSGASEALTDAIKRGASGEIEQLAEKFGKDVSQQVSRNISLNVMETEMEGIEKLVGGVAKKLAQDAIKTAEQFSQQCVKAIMKKSVTTILKDIATSPLLIMQKCTAAAGQVNSGQLAIQSANLRKEIEKLILDQDFTQFMDEWVERNKQHQLKQLKDTSEAAQDTVTKLSDNIKQNSMLQTQIAGSL.. 485
6 -12.100IDP91469 putative secreted protein EspD [Vibrio parahaemolyticus RIMD 2210633] VPA1362 [Vibrio parahaemolyticus RIMD 2210633]  ali follow..  14  63............................................................................................................................................................................................................................................................MKQVADSVSGSGQEKVATKKGLIELQKDSQIAMLNERASQLEEQ----KKAQQTQGILGKI-----MAFGFIAAIIMAPFNPVMAAVMIGGMVASLV----------------------------IPKIADEIMKSAGVDEKTRGIV-----KMGLDIAIGLGTMLLSFNPAGIASSAGKAIAGGAAKAAALVKRKSFTAISSKAGGLAEKIRKSAQPLLDKIQEFAKGGQMSAARIGQASSVGSNVTSLVSTGYGI-------KTADISKQMEVNQAKQDELQTRIEQVLKMLDQAMRSVAHSFETLIKTNEDYRSFSKTMTS.... 346
7 -8.390IDP91721 gene: MMRN2; multimerin-2 precursor [Homo sapiens] NP_079032 [Homo sapiens]  ali follow..  177..........................................................................................QEHLLGDLQNDVHRVADSLPGLWKALPGNLTAAVMEANQTGHEF---HVDTFLQVHFSPIWRSFNQSLHSLTQAIRNLSLDVEANRQAISRVQDSAVARADFQELGAKFEAKVQENTQRVGQLRQDVEDRLHAQHFTLHRSISELQADVDTKLKRLKAQEAPGTNGSLVLATPGAGARPEPDSLQARLGQLQRNTLEDMRATLTRHVDEIKELYSESDETFDQISKVERQVEELQVNHTALRELRVILMEKSLIMEENKEEVERQLLELNLTLQHLQGGHADLIKYVKDCNCQKLYLDLDVIREGQRDATRALEETQVSLDERR----------QLDGSSLQALQNAVDAVSLAV--DAHKAEGERARAATSRLRSQVQALDDEVGALKAAAAEARHEVRQLHSAFAALLEDALRHEAVLAALFGEEVLEEMQTPGPLPLSYEQIRVALQDAASGLQEQALGWDELAARVTALEQASEPPRPAEHLEPS. 681
8 -7.850IDP95025 Set165a_026 [Vibrio cholerae O1 biovar El Tor]  ali follow..  12  1...............................................................................................................................................MSNAGVVEKFVYENIIDNRKAVRGMRKFEEMTRKHSAKITKLFED--TEKSKQRAIKNTEKEEVKAATKKLTAEQKAAAQAEKLKAQEAAKLKKFNDWKLAQFRSAAFERLSLEQKMELKRVLSAKRSEEEIREEYRQTTAMMRRENQRRAAYERKQSKINNSGV-GGGIVALAGNPAALAAAAVIGGGAMAINSVGLDYNEFAQLANGLIAVTETIPDVSTAAD-KIKDLLDRSGEVMAETVFDSDKGEFDKGEGSILANLLLKQGVITGDKESLNNFMNQSPDKFIESVVKATEGLDAKQQAFVLEAFGSDFYNII-RGIQTNRQGFEAGKQNAVQFTAATEFNKSVASMVSAISNADLNIFKSFTEFLSPSSLAMFGKLGELLNSITLLGYTLSGALNLLSPAINLVLDGLNLLLVGLTNVQRYITELTKYV.. 459
9 -7.830IDP91681 LAMC3_HUMAN [Homo sapiens]  ali follow..  1078.........................................................................EQMMSLEGAVKAAREQLQRAGSQKTCTQLADLEAVLESSEEEILHAAAILASLEIPQESQPTKWSHLATEARALARSHRDTATKIAATAWRALLASNTSYALLWNLLEGRVALETQRDLEDRYQEVQAAQKALRTAVAEVLPEAESVLATVQQVGADTAPYLALLASPGALPQKSRAEDLGLKAKALEKTVASWQHMATEAARTLQTAAQARQTEPLTKARSRLTA-TSASQLHQEARAALTQASSSVQAATVTVMGARTLLADLEGMKLQFPRPKDQA-------ALQRKADSV--SDRLLADTRKKTKQAERMLGNAAPLSSSAKKKGREAEVLAKDSAKLAKALLRERKQAHRRASRLTSQTQATLQQA--SQQVLASEARRQELEEAERVGAGLSEMEQQIRESRISLEKDIETLSELLARLGSLDTH----APAQALNETQWALERLRLQLGSPGSLQRKLSLLEQESQQQELQIQGFESDLAE-IRADKQNLEAILHSL.. 1579
10 -7.800IDP92775 hypothetical protein [Vibrio cholerae O1 biovar El Tor] AGG09416 [Vibrio cholerae O1 biovar El Tor]  ali follow..  1..................................................................................MAENLVRYGASLAFDGRQALRQLRKYKETFNKVQHTILKNTQKLNNEMVQGEQRVQRAKENSIEKEKRRQESFNQWRKRQTRSANFAELKAHQQVELMKILASNKSAQEIKSTYTDTLLAFKLAKKREVAAEKQANRLRLESAKRTETRIKAIKGRANNLLGRAGGVAGSAISGLLGLGAATLGTVAVGAKDASDTRAEAVQDVNDRRGEIMNLEIKDGEIK---GELTDLLNFLVKNGQLALDAIKDFVLNSGNSAEFLEKVFKLLQTSGADTNTQTFLMESLASNSLMAQIDQNSTMYARSLEEM-IDAANQTQVRDVGQTMSAMWN------KLTYLPLEAFEAFAMAIKPETAASMNS-VVNSIIKLARAMGDDLANVLERIVPWLEKLLA....................................................................................................... 427

FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Wooley JC, Godzik A. Probing metagenomics by rapid cluster analysis of very large datasets. PLoS ONE. 2008;3(10):e3375. Epub 2008 Oct 10.