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Query: IDP04239 sensor histidine kinase [Clostridium perfringens ATCC 13124] CPF_1057 [Clostridium perfringens ATCC 13124], from CSGID

Results of FFAS03 search in CSGID
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MSKKNKPKNVTSIAIKINAISVRDLFFRFLAIDICLIIILIILWCIQAEKDFYGELVKNAQRSFNFFPIENSTYTVVWSNGKTMVKEAGAFLYYVRKIVIILGIVEGVFLLEEIIFGTAKIRKTLKPLNEIAETASRLSNMDFDEEKFQSLEDAISKISPVTSDERIHIGDSELKGLEDAINKLLDRMRDSYRQQARFVSDASHELRTPISVIQGYANMLDRWGKNDESVLEESIIAIKSESENMKNLVEQLLFLARGINGKTKLTIKEFSLNNMIDEVFEESKMIDKNHVYNYIESEHITVQGDMALLKQTARILVENATKYTEEGEIITLKVGENSKGEAYFSIQDNGIGMDENDVPHIFERFFRADTARVRKNGGTGLGLSIAKWIIDNHKGYFSVLSRKGIGTRITVYLPQNIKLast
1 -105.000IDP04239 sensor histidine kinase [Clostridium perfringens ATCC 13124] CPF_1057 [Clostridium perfringens ATCC 13124]  ali  100  1MSKKNKPKNVTSIAIKINAISVRDLFFRFLAIDICLIIILIILWCIQAEKDFYGELVKNAQRSFNFFPIENSTYTVVWSNGKTMVKEAGAFLYYVRKIVIILGIVEGVFLLEEIIFGTAKIRKTLKPLNEIAETASRLSNMDFDEEKFQSLEDAISKISPVTSDERIHIGDSELKGLEDAINKLLDRMRDSYRQQARFVSDASHELRTPISVIQGYANMLDRWGKNDESVLEESIIAIKSESENMKNLVEQLLFLARGINGKTKLTIKEFSLNNMIDEVFEESKMIDKNHVYNYIESEHITVQGDMALLKQTARILVENATKYTEEGEIITLKVGENSKGEAYFSIQDNGIGMDENDVPHIFERFFRADTARVRKNGGTGLGLSIAKWIIDNHKGYFSVLSRKGIGTRITVYLPQNIK 418
2 -90.000IDP04076 sensor histidine kinase [Bacillus anthracis str. `Ames Ancestor`] GBAA2213 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  28  54...NADSAKKVDAISLLQPYLPSNGMIRIINENSKVMIRQEVDSTKPIPNTKFERKESAGIYEKNEGKFAYIKIPIIWNDGLEMTERLDSLQENLNMLKNVLVIASLLVLIPSFFAGRMLSKFILKPVNSLIQTMEHIQVRGIFKKIPLE-----------------NKSKDELHKMGSTFNKMIDLLHQNFEKQQQFVSDASHELRTPLTVIESYAKLLKRWGMKKQDVLEESVEAIYSEAVRMKGMTNQMLLLANSSADW-SLETNESDLVRLCQVTAEQLEKTYARNFRVITDEEKIVVNIDEQKIKQVLVVLLDNAMKYSKDSIDIIVGI---QKEKVFFSIQDYGMGIPKEDIQKVFDRFFRVDKARSRETGGTGLGLSIAKQIIDAHEGDIQLESEEGKWTKVTVNLPH... 450
3 -86.900IDP04397 sensor histidine kinase [Bacillus anthracis str. `Ames Ancestor`] GBAA3230 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  20  52SVEDIEYKHGQLKMDDDFETFEDGVNIIIYNKQSELLAGNSPTSFNKKISL---KSDEIQIIKDGNKEWIVYDFLHNADGGVRGIMTMSRLSSTMNTLIVLTLISFPLLILIAAVGGYFITQRAFRPVQQMSDSASKIGDGDLSKRINLK-----------------GSPKDEMYHLAQTFDKMFERLETSFESEKQFTSDASHELRTPTSVIISQCEYALSQRN-NPKEMEESLEVILKQSRKMSALISQLLLLARADQGNDTFQFECINMSELTEIVVEELSLMVQEASIDITTHEDLFIKADQTLMMRLLMNLLTNAIAYSKANGTVHMQLFRD-ETNIIGKVSDNGIGISEQHITKIWDRFYRVDAARTSNIGNTGLGLSMVKWIVELHGGEITVESGLGEGSTFTFKLPIEKQ 456
4 -79.800IDP04304 sensor histidine kinase [Clostridium perfringens ATCC 13124] CPF_2640 [Clostridium perfringens ATCC 13124]  ali follow..  26  1.......................................................................................MQNELVFLDIVNKIILGIGVLLILASTIMGFIISRSITRPINKLMTKAKYISKGEYDKKIE------------------INTDILEINDLINSINNLSQSIKEQENIRKRLTGDISHELKTPLTNIQSHLEAMIDGIWEPTE---ERLLSVKEEAERLSSLVSDMQKLNKYDESSIKLKKDNVNISDIICFVIFQFSNLAKSKNIKIEYEKNINLYCDKDKITQALVNILSNAIRYSNEGSTIFIEEKLK-DNKVIISIEDQGIGISEEDLKYVFERFYRADKSRTRATGGTGIGLTIVKSIVSSHGGEVKLESKLGEGSKFTIILPKED. 309
5 -79.500IDP04662 sensor histidine kinase [Bacillus anthracis str. `Ames Ancestor`] GBAA0650 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  22  74.......................ETTVVITNTNKEVLAKSNKINTTIKNHISSMQTRTIIENHWKTSNYICTVSPIIVAGYVYMFLGTESIEKLVNGLTKQFIIAGAITFLLTVITIFLLSRLLTKPLLHMKHATEKMSKGDLSVSLTT-------------------TRNDEIGELSSSIQTLANDLHYMKTERSEFLASVAHELRTPLTYVRGYADIALK-ETTSPEQRLRYLSIIKDESDYITNLVQDLFSLAQMEQHNFSIQVKEVHLHTFLTRISEKVNAMYKERYITVSCPPTLLVNLDEQRFEQVVVNILNNAYRHSKEHSQIHISVIEE-NKRISITMEDEGEGIPPEDLPHIFERFYRVDKARSRATGGTGLGLSIVKEIVELHGGNITVTSEVDHGSCFTISLPSIKK 458
6 -78.400IDP04542 putative two-component system sensor protein [Yersinia pestis CO92] YPO2000 [Yersinia pestis CO92]  ali follow..  19  82.....................GGRVQYWVLSDDPQLQVGGPAPRGVTWASLSKGFSKVPGATDESCSLFLLMSEIPAQGERYVVAIDSTPYMGTLNEFTRTLIVITAIGVLFVALLGFVIARIGMRPVNKLSEQAQHLAPGNHGQRLD------------------TLTLPDELQKLAVAFNGVLERQEIAWRQLESFNADVAHELRTPLTNLMGQTQLGLSRKR-ETHELEDLLESNLEELERMTSIVNDMLFLSHAQAGEHATQLTDVSLREETYKTTEYVEPSFAEKNLSIHVEGDITARIDRRLFHRSLANLLENSARHAVTGTTVKVTISRE-NNLASIAVANIGAPIAAEHLNRLFERFYRVDSSRARSDTHHGLGLSIVRAVAIMHRGDVFASSQNGINT-FGLTLAITDP 461
7 -78.000IDP04667 sensor histidine kinase [Bacillus anthracis str. `Ames Ancestor`] GBAA1313 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  23  75.......................SSDVLFVSNPRDLSACLPFDVHHHSLISEGKTVTKIGYEEHFERNIMGVVIPVLENGIVYSYIPLKSIKDLIYDMGLILAPLALAITLLTIWIGRKIIIAITRPLSQMERVANHLATGDFSERITI-------------------SSEDEIGRLGKAFNKMANSLETEDVKRKEFLANVSHELRTPLSYIKGYSEAILD-GVAKGPQQEKVTQLIHKEADRMQRLVHDLLDLAQLEGEHFPLQKQPIVFSQLIEDVLDTYEIKFIEKKIRINLNPEIIVMIDEDRMQQVLHNVLDNAIRYTNQNGDIMITLRQI-DDYCELSIKDTGIGIDTEHLENLGERFYRVDKARSRQHGGTGLGLAIVRQIVHIHDGQWQIESEKGNGTTVSIKLKVQNE 462
8 -76.600IDP04352 sensor histidine kinase [Bacillus anthracis str. `Ames Ancestor`] GBAA0584 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  20  106.......................DIAIIITDNNGKIISTSEPVTKAMQKQLTCKTEPIIVEKNWKKSKFITTVSPIHTTGKLYMLLKTSFLENMLLKLMKQFLIISVLTIILTTISVFIFSRVITEPLIKMKRATEKMSKLNKPIQLGI-------------------KRNDELGSLAKTIEDLSSELTYMKKERGEFLASVAHELLTPLTYMKGYAKVAKR-DSLTKEEREEYLQIIEDETDSVTDLVQDLFMLVQLEQHQFVIKKQKVLLRPFLERMVEKTKTTLTNKQMQLHVYDDLEVCIDERRMEQVMLNLLHNAYQHSLENTTITIRVLAE-TNSFTISVQDEGEGIPEGDIPHIFDRFYRVDKSRTRATGGKGIGLAVAKEIVELHNGSILVTSKLDVGTNFIIELPFE.. 487
9 -75.700IDP04674 sensor histidine kinase [Bacillus anthracis str. `Ames Ancestor`] GBAA1956 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  24  38.......................................................................................LAIHLSPFVTYLISDILSFIFMILVWILIAVLMRPKREAMIWTIIEPIQKIAKGDFSVKIRNEE-----------------KYDGEIGVLVKSINDMTDELNAMEKMRQEFVSNVSHEIQSPLTSIKGFARALQD-TNLPEEKRKHYLTIIETETTRLSKLSQNLLKLTLLESEEYTPERVTYRLDQQLKQIVLNSEPLWAEKEIELDLDEKVHITADQESMSQVWINLIHNSIKFTPSSGTISIKL-KEYETLVEVRIRDTGSGISEEQKQHIFERFYKADSSRNRAYGGSGLGLAIVKKVLDLHQGEIKVESEEGNGTECIVCIPNYEE 350
10 -74.800IDP04302 sensor histidine kinase [Clostridium perfringens ATCC 13124] CPF_2503 [Clostridium perfringens ATCC 13124]  ali follow..  21  79.......................DAQVQIYNLKGQLIMDSIGLEPKEYNTPVDDTAKWVGTVPDYTGKVMAISAPLRNSSNIRYISSLRNVDNFILNFFLVFLVIGLTVLAIGIILSYFLANSIVNPITELIKVSEQMAKGNLKVRNKI-------------------VTNDEIEKLADSLNIMAEEIENREILKNEFISSVSHELRTPLTSIKGWAITLNN-DFTDRETLKMGFDIIEKEADRLSNMVEELLDFSKFVSGKIKLKYEEINLKEFIEYLRLYMNPRAEREHKELILKEDFIIVGDKDRLKQVFINIIDNAFKFTHENEKITIEFVYA-DEGIYINIIDTGCGISKEELPRVKEKFYKGKNSKS----QNGIGLSICDEIIALHEGTLEIYSELGKGTKVVIYLPKKLI 463
11 -74.100IDP92003 sensor histidine kinase [Streptococcus pneumoniae str. Canada MDR_19A] SpneCM_010100002775 [Streptococcus pneumoniae str. Canada MDR_19A]  ali follow..  22  5...................................................................SYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTIVASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEV-------------------QGPVEFQQLGQTFNEMSHDLQVSFDSKGLMIAQLSHDIKTPITSIQATVEGILD-GIIKESEQAHYLATIGRQTERLNKLVEELLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERRDVHLQESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKD-QLSISVTDEGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLGSTFTLVLNLSGS 346
12 -74.000IDP04660 sensor histidine kinase, putative [Bacillus anthracis str. `Ames Ancestor`] GBAA0286 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  20  1.................................................................................................MDPKVKISLFITLILITMYLFFSRIQFIQNHKSIDTKLSRALKGNLQTRLFT-------------------SNDQSLHNIVFSINELITELEKVRIKRKQLLSSISHDIRTPLTSIIGYIDALKDGVAASEIEKQEYLKILYMKSNNLKHLVDEIFNMAKLDANEFPLKEEKLDFSEVTREVLIDFLPEISKHNIKLQVESTCPIIADHLSLMRIIGNLMKNAIYYGKDGKTIGVEL-LETDAAYELLIWDKGPGIPKHDLQNVFERMYRSEQSRNSSFGGSGLGLSISKALVEKNGGHIWVESIPWERTTFGFSIPKHNT 311
13 -73.800IDP04673 gene: resE; sensor histidine kinase ResE [Bacillus anthracis str. `Ames Ancestor`] GBAA1498 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  24  79..........................IIIVEEGKEISSSPKVFTDKKEIKNKVRKASNSRKNKNTENDIMIVGKPVQSKNEVFVYESLQVPIQGMERTTDFIFLSAGIAIILTTFFAFFLSTRITAPLRKMREVAFEVSRGKFDAKAPM-------------------VSQDEIGELATALNQMGKQLKFNMNARQDFIANVSHELRTPMVMLQGYSEAILDDIVQTKEEINEFVQIIYDESVRLGKLVNELLDLARMESGNVELHIGEVDIHPFVEKIGRKFQGIAKDKEVALTVDSIEQYPFDADRMEQVLTNLIDNAIRHTNAGGHVTLVIDTK-NNGLIFEVQDSGAGIPEEDIPFLFDRFYKADKARTRKKGGTGLGLAIAKNIVQGHGGKISVSSVVGEGTTFSVYLPNR.. 589
14 -73.300IDP95472 sensor histidine kinase [Listeria monocytogenes 10403S] YP_005962624 [Listeria monocytogenes 10403S]  ali follow..  18  55IRYSPQDATMQVLNTYQRILDVKKIHYTIKNANDETIYPTQMNSADDKKKLESGETVSKKIDNRFNKEMTIVYVPIMNGGSIVLNSPISGTEQVIGTINRYMFYTILLSITVALILSAILSKLQVNRINKLRAATKDVIQGNYNARLKE-------------------NNFDEIGALAIDFNKMTQTLETSQEERRQFIADVSHEMRTPLTTISGLTEGLVN-DIIPKSETDRCIALIDTEARRLTKLVNENLDYEKIRSNKIKLQKTRFNGKEFLELIKEQLDYVASEKGNTIAIDKDMAIYADYDRLTQVFINIVKNSVQFTE-NGQITLTGTQD-YKESVLTITDTGIGMNTEELEQIWERFYKADMSRTNTAGESGIGLSIVKQLIEYHDGSITVTSEPNKGTSFTIRLPFFQD 473
15 -73.200IDP04371 sensor histidine kinase [Bacillus anthracis str. `Ames Ancestor`] GBAA4776 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  22  4.....................................................................................................LLISIIFILLCVIYIQYKMRKNSSENLRYTYEKLESIVNEKTGEKLL------------------VMTDDLELQKLLVAINQLLDAKQKTNADMRKMLSNISHDLKTPLTVILGYTEMLNKDKTMSKEEQQILLEKVHVKTLEVMELIHKFFDLAKLESGDKAIEMTKVNMNEVCREKILSFYDLVTSKGFHVHIERNIYALGNVEVLGRVLNNFISNAITYGDDGKTLGMTL-RDDETNVYIDVWDTGKGIDESHIDKVFERMYTLEDSRNRLYQGSGLGLTITKRLVEAMDGKIHLSSKPYEKTIFTVALKKMQ. 310
16 -72.100IDP04661 sensor histidine kinase [Bacillus anthracis str. `Ames Ancestor`] GBAA0572 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  35  177...................................................................................................................................................................................LAGRALVPIQNSWEKQQQFVSDASHELRTPLAVIQSKTDILFQSPSATIEEKAMDISTISKECRRLSKLVANLLLLARSDSNQIEMDKKIFELDKLLEEIVEPYKEIASYQEKEMKVEYDISFMGDRERIHQMMVILLDNAMKYTNEGGHIQIDCTQT-NSSIRIRVKDDGIGVKGEDIPKLFDRFYQGDKARSAS-EGAGLGLSIANWIVEKHYGKISVESQWGEGTCFEVILPKNQR 415
17 -71.800IDP04331 sensor histidine kinase [Clostridium perfringens ATCC 13124] CPF_2181 [Clostridium perfringens ATCC 13124]  ali follow..  25  158...............................................................................SIIIAITSFQAIEEASALIKDFYKYIILIVIVIGLILSYVFSNLISKPLVKLNKSAKKMSAMDFSEKCDI-------------------EREDEIGNLAKTLNFLIEKERELEKLRKDFIAGASHELKTPIGIISGYAEGIKD-GIVDHKDQGVYLDIIIDEAEKMNKLVMDMLELSKLEAGKIDLHIIDFSLTELTEEVLVKNSVDINKNNLTVVKNEDLYVQGDDFKIEQVLTNFVTNAIKYSEPNNQIIIDIKPVEEDKIYFSIENTGAHIPDSDINKIWTQFYRGDTSRNRGSRSTGLGLSIVKNLLQAHESEFGVMNT-ENGVKFYFTLKKSKE 500
18 -71.800IDP04258 sensory box histidine kinase [Clostridium perfringens ATCC 13124] CPF_2010 [Clostridium perfringens ATCC 13124]  ali follow..  23  73.......................NIRITYISKDGNVIFDTHKKLINDNESYLKRQEIIEAIESGLGSSVRYSALKLKDGSIVRTSIAVENAKILDSINSNYLLVGVILSLVIALLLTVKITNIILNPLKELEQLTSTIASGNFHKRVK------------------INSKDDEIQRLGKSFNYMAEQLEITMERRSQFVANISHELKTPLTSIKGFAETL--RYVDDDETRNKFLSIIDEESDRLARLLEDILCLYEIEQKR-STVLEEFNVDEEIEKVYMLLNDQAKKKGVEIDTNSNCVLMGDKDKFKQMLLNLVSNSVKYTEKGGKVRVESYNR-DMNLVLVIEDNGIGISAEDLPRIFERFYRVDKARSRESGGTGLGLAIVKHIVRLFDGEINVTSELGVGTKIVITIPIN.. 570
19 -71.800IDP04694 gene: yycG; sensory box histidine kinase YycG [Bacillus anthracis str. `Ames Ancestor`] GBAA5714 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  21  98..........................VSVFDANRKLLAISDESKQNQRVLVQKKPEVKIEKDGRTGHRVQVMITPIMDDGAIYVVASMEDVYKQMKDINQIFATGTVIALLVTAVLGILLAQTITRPISDMRRQAIEMAKGNYSRKVKV-------------------HSHDEIGQLALSFNNLSKKLQQARSSRREFVANVSHELRTPLTTMRSYLEALTDGAWQDPNIAPQFLTVIQEETERMIRLVNALLQLSKLDSTEHRLMKEWVDFTDFFNNIIDRFEMSKEQNSFKRSFSKKRFIDMDTDKITQVLYNIISNALKYSPEGGTVTYRLRDRGE-LLEISVSDQGMGIPKENVDKIFERFYRVDKARSRQMGGTGLGLAIAKEMIEAHGGSIWAKSEEGKGTTIYFTLPMAAD 607
20 -71.300IDP95462 sensor histidine kinase [Staphylococcus aureus subsp. aureus USA300_FPR3757] YP_494944 [Staphylococcus aureus subsp. aureus USA300_FPR3757]  ali follow..  18  51ARQYEQSAKPTHIQQYFKHLGQMNYQIMTIDQKGHKTFYGEPFREDTLSQNAINNVLNNQDYHFDNVTDNTVGINFKTKDGSIAVFMRPDIGETFSEFRTFLAVLLMLLLFISISLVIASTYSIIRPVKKLKLATERLIDGDFETPIKQ-------------------TRKDEIGTLQYHFNKMRESLGQVDQMRQHFVQNVSHEIKTPLTHIHHLLSELQQT--SDKTLRQQYINDIYTITTQLSGLTTELLLLSELDNHQHLLFDDKIQVNQLIKDIIRHEQFAADEKSLIILADESINFLGNQRLLHQALSNLLINAIKYTDVGGAIDIALQHS-HNNIIFTISNDGSPISPQAEARLFERFYKVSKHD----NSNGLGLAITKSIIELHHGTIQFTQSNEYVTTFTITLPNNS. 456
21 -70.900IDP01779 gene: phoR; sensor histidine kinase PhoR protein, putative [Coxiella burnetii RSA 493] CBU_0366 [Coxiella burnetii RSA 493]  ali follow..  27  3.........................................................................................................................................................................QRTHKLNLKKLPKAVREHINQLERIRSDFVANVSHELRTPLTVIRGYLETLLKKEVRDSKSYQKIFQQMYQHSARMETIIDDLLLLSRLESDDHPTEEKNVAVPEILKTLCADAERISGEKQIQLKAEPNLYISGSEEELKSLFSNIIINSVKYTPSKGRINVKWYRDDDH-AVFSVVDTGIGIAKVHIPRITERFYRVDKARSRESGGTGLGLAIVKHVLMRHDGELHIESEPGKGSIFTCRFPLV.. 251
22 -70.800IDP04428 gene: phoR; sensory box histidine kinase PhoR [Bacillus anthracis str. `Ames Ancestor`] GBAA4832 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  23  80..........................IAFVDEKKKVQYSGGQGIMKELSSETKKQRNKVITKEADQNNEFYHAVFVQDVTGILVKSTIEPLKDVHQKTWGLLIIGFVIACLVVVFLGMKITGQYIRPIESVTKVAIELAKGNYKARAYE-------------------SHSDETGMLSKAINILARNLQEMTLERKDFLANVSHELKTPITSIKGFSETLLDGAMDNKKFCEHFLHIILKESERMQGLIEDLLDLSKIEQQGFKLSMGTVDMKGLLEDIHMVLDNKAGEKEISLNTLKRVSVIGDPSRLQQIFINLMNNAIVYTPAGGVVSVELAED-KYNAYIKVSDTGIGISKDEIPRIFERFYRVDKARSRNTGGTGLGLSIVKHLVEAHHGTITVDSEVGEGTTFTVVLPKSAT 585
23 -70.600IDP04243 sensor histidine kinase [Clostridium perfringens ATCC 13124] CPF_1140 [Clostridium perfringens ATCC 13124]  ali follow..  31  179...................................................................................................................................................................................LSSKVIKPIKKAYDKQVFFVQDASHEMKTPLAVIKGKLELLANSWDDKIEDHFEHISKMMSEVRDLEKLNSDLLLLSKEDIDN-SVNIVSFELEEFIEDLSEFYVDLAEVQEKNFIVNTPVIVKWDYSKVKRMLIILLENAFKYTEEGGKISLSFEEV-NKNIKIIVCDNGIGIKEEDIGRIFDRFFRSADVRGKNIKGSGIGLSLLKSIGKTLGTDIKLYSKYGIGTKFEITIPKILN 418
24 -70.500IDP90001 gene: qseC; sensor histidine kinase FTT0094c [Francisella tularensis subsp. tularensis SCHU S4]  ali follow..  20  91.....................NKSIGFIVYDRKHKKLLLKTSNLPNFHKNYDGITSTTGTNEEDGQKNWYTYTLKTDNGNLITVFANDTIKDKISRQIIFKFALLLASTYIVLIGFIYYILKTALHPLERINKRVAKINPRKNEK-------------------LNEDVIPYEIKSIVDQINLLIEKFHETLEREKRFSGDAAHELKTPIAGVKTLVEIALA--SDDIDEIKQKLERIKSSTNRYSHIIDQLLTLSRIQPNEQVTFGKKLMINKVLESFIAENAIKAIEKNIEIVFYQHLYCYSNDYLLGILFKNLISNAIKYTPNGGLIEISSYQE-ENNIVVEIKDNGIGVPQENIERIFDRFYRETGTGE---EGSGLGLAIVAEIVRLHNGKIFAQNNIQKGLTITVKIPIDHK 471
25 -70.100IDP04182 sensor histidine kinase [Vibrio cholerae O1 biovar eltor str. N16961] VCA0238 [Vibrio cholerae O1 biovar El Tor str. N16961]  ali follow..  22  185...............................................................................QQQRTSRYEEAALDALSNVRSVITSLAVFGMVSGALLGVWLLRTLSKPLAELVKSTTALEQGRLDHRISI-------------------SGPDELKTLARHFNYMAQSLEKAKHQQKEFFANVSHELRSPATAILGEAQITLRSRHNSDDEYRQTLLRISESAEQLAFRIEDLLMLIRHDERLFHPALTELLLGEIWQAVVRQASLLTHAQQVELTVNQTQLCYTDCDKLLMVIRILVDNALRYDPTQQPIGLNLELD-EEAWRVQLVDQGIGIAEADLSVIFERYFRAENGKRYRPDGLGIGLTLAQSIVKQLDGEIRIESVLEQGTTVTLTFPRGEE 542
26 -70.000IDP04438 gene: cpxA; two component sensor kinase [Yersinia pestis CO92] YPO0073 [Yersinia pestis CO92]  ali follow..  16  75................IEKWAPPGQHLILVTSEGRIIGVQRQEVQMVRNFIGQSDNADQPKKKKYGRVEMVGPFSIRDGEDYLIRPANSPQSDFINLMFDRPLLLLIATMLISAPLLLWLAWSLAKPARKLKNAADDVARGNLKQHPE------------------LESGPQEFLATGASFNQMISSLDRMVVAQQRLISDISHELRTPLTRLQLATALMRRRHGEG-----KELERIEMEAQRLDSMINDLLVLSRSQHKN-ELHREPIKADELWSDVLENAQFEAEQMGKTLVVTGPWPLFCNPAALDSALENIVRNALRYSHHHIAVAFSI---DNQGVTIIVDDDGPGVSPEDREQIFRPFYRTDEARDRASGGTGLGLAIVETAVSQHRGWVKAEDSPLGGLRLIVWLPLHPL 456
27 -69.400IDP04691 sensory box histidine kinase [Bacillus anthracis str. `Ames Ancestor`] GBAA5067 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  19  220..........................VQLPDVTGPINPIYKNSIFLDNIKEFQTDLLLKESKHIQDIKYKLLIKPIKEKDEIYAMASLQPVDEAVQMVQDYYIYIIAFVVVLIFLASFYYSKQIAKPLLKINDTTKKIAHLDFTEQIPI-------------------TSKDEIGDLSKNINTLSNKLNSHIGQRKEFISGVSHELKTPLSIMKSCISILKDGVAEHKK--EYYFQAMEREVDKMDTLILDMLELAKFESGTYKMKKDPFYIDTVMEAICEHLSVEIEKKELRVHKHGPFEVVANQGRIEQVIVNFITNAIRYTPNKEDIIIST-IDEKDHIKVCIENKGTHIEEEQLDKIWDRFYRVDAARQRSQGGTGLGLAISKNILELHDAEYGAENT-EDGVLFYFYLPKK.. 616
28 -69.300IDP04433 sensor histidine kinase [Bacillus anthracis str. `Ames Ancestor`] GBAA5276 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  17  146.................................................................................ASKTNDAQDDPKLTDALQQLAPHIGATMLALSLLGSLIYAKIIAKPFQYMSDALKDIMNLDFSDKKLLNKNTDQTDFNLQVAASQVPNIVKNLHASNQDLRNELKKEQQLEQSRKEFMSMVSHELKTPIAAVMGQLDGMIHGIGAYKDR-DKYLKRSYEMMQDINILTEKMSELSKIQNPQFKPDLKVISLTNIIEDVMKKVDYFVSVKQLNVNIKQDVQVLADPKFIQTAIFNIISNAIHYTIDHQHVYIKL-YEKPNGYALEVLNTGSQIDEDKLAHLFEPFYRANPDKHGLVQGSGLGLYIVKQILDKHQFPYGIQNT-PQGVKCSIVFPKA.. 479
29 -69.100IDP04189 sensor histidine kinase [Clostridium perfringens ATCC 13124] CPF_0225 [Clostridium perfringens ATCC 13124]  ali follow..  17  93......................YNVRIQIISNSAQIIYDSSSDEFGSDINESLDGQTAYIVEKIDNVPTLFLSSPIFYKGAIRLILINTEAYEILRNTLTIFIISGLIAIVIAIFLINTFAKELVSPLMILKQKSKNISEGKFKEELHI-------------------TSGDEVEDLANTFNIMSENLDKYINEQKKFFDNVSHEFKTPLTAIIGFSEIIPKL--NDKEKIVQSSALIEKEGKRLLNLVEEILLLAKSNKNTFEIEYTYIDVKSLIEDCLKILKIKLDNYDIKVYRNESFFIYGDHDKTKQVFINIIDNAIKYSG-CETLSISTKRS-PNKMEVIIEDDGTGFIIKD--------------EYVNPKGNGLGIKICKDIMQSQNYGFNIESELDVGTKVTLSFSIGKN 466
30 -68.900IDP04012 gene: virJ; sensor histidine kinase [Clostridium perfringens ATCC 13124] CPF_2355 [Clostridium perfringens ATCC 13124]  ali follow..  18  85.......................KCQIDVFNEDLEKEYSYYLDDFSDVLKEANKNKAALNIYRDENAVKAYLAFPVYVDESILLSKDYSKEYLELRDLMSNIKFIVSITFLLILIFTYFLFERIINPLNYIKNSFKRIGDGDFKINLKV-------------------NSKDEIGDLACGVNKMANKIEEQIEKRTEFFNNITHELKTPLTNISGYAQIMSEEDFHDNDFRKFALERINKESKRMHELIVSLIEISKNKSDIEGGEIENVNLKTLIEDLCEDFKVKGDKQGICISNNEDIEFMCREDEIRRIIINLLDNAIKYSIKGSEIEISLFKD-KEEKHIEIENLSDEISSEGVEKIFEPFYRENTKKSRELGGNGLGLYICSELVKKYGGDISFNYSNGKVK-VSIIFK.... 482
31 -68.800IDP04419 sensor histidine kinase SrrB, putative [Bacillus anthracis str. `Ames Ancestor`] GBAA2861 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  21  141..............................................................................DMLILVGVSIAHSNEIIKTLNSFYLFILVITIFLIIVLVWILSKTITTPLKELSDVAEDISRLQFKK-----------------------KTNDEIGDLATSINIMSEKLQEAHQDLKRFMGDVTHELKTPIALVKAYSMGIK-----DGLDDGTYIDTIIKQSDHISNLIEELLRFSKLERDV--LQKEEFSIKSLVQSILDKHKIELESKEINLQVNGDAIVYADVNKMRMVFQNLISNAIKYTS-NQNIKITL-EDRNESVYFQIQNGMNAEHMKDIDKIWEPFYVLESSRSKDRSGTGLGLAIVKSIVERHGFDYGVVTI-GGEIRFYIHMKND.. 458
32 -68.800IDP04007 sensor histidine kinase [Vibrio cholerae O1 biovar eltor str. N16961] VC1319 [Vibrio cholerae O1 biovar El Tor str. N16961]  ali follow..  20  116..............................................................................SNEQIYLLKPDSHSPVYQAIDRADNLLFVFMLGGFALYCMFLIWFLSRRLRELERVTHDFANGNLQARAST-------------------KSSKSVGKLNHSFNMMADKISHLILSNKALTNAIAHDLRTPIFRIQWQAEVLAES--QLNAKQQQQVASIIEDTEEMETMVDELLYYAKLEHPESDIQSQYLEVNQWLADFIDEQSHKSSLQIQYLPSLQPLMLDADPQLLTRALVNLIRNAEKYA--GDRLLIEASTV-DAKLCIAIHDNGPGIEEQHWPHIFDAFYSTDSSRNKAQSGFGLGLAIVKQIMARHQGEVTLTKSPLGGACFSLWLPLYPN 431
33 -68.700IDP01736 sensor histidine kinase [Bacillus anthracis str. `Ames Ancestor`] GBAA5503 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  19  82.......................DVRVQMIGKNGDVVADTQKGARNIDIESSLKGKKSYVFEEGDPAPILLFSSPVYYGGSVRFINELTGEKEVLTNVGWTFLMTSLCLVAAGIFFAIRLAKSLHKPIDQLRQMAHRLANGDYKSKIEL-------------------NEYVEIAQLSASFNAMIKQLKEEKEKQKDFLDRITHELKTPLTAIIGYVDLIPK--LKAKEDVKESLRYVAVESERLLSLVEELLKSSKYGTSTFEISPTVVNIKELAEEAVSIVKPRLQKFEIEVINETDVHVVADFDKTKQIFLNVLDNAIKYSD-ATQIRMNVIVN-EREAKVFVHDDGIGIDEGVLAEWNESPEG---KILPSSYGHGYGLYICQEIMDKQGGSMRIESSEEIGTTIFITFLLPRR 465
34 -68.700IDP04665 sensor histidine kinase [Bacillus anthracis str. `Ames Ancestor`] GBAA1118 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  18  179.......................KATLQIFNSKGDEVFSYPNGKKKTFSVIQAALNEREPWNHKENTSSFYNHLLVVTAKNEHYYPDDEIDDVFTKKFLIGCGLILLIVFVYLVILSIWYGNKFGKPLLHAMRWLKNIAGGKYEEPVSKKGKPIRFRKSG-----KEKWSFRLFSDVTNSLEHLSITLKKNDQTREEWITGLTHDLKTPLSSIYGYALLLESKQYNTDRDIQQFGSVMKEKSQYMTTLIDDLSLTYQLKNNSLPAQHVNIEMNQFVQKVLLQFINNPTLQNQNIEFSNKIQYFIEEKWFQRIIENLLVNAVKHNNETTNVIVKLSQNATS-FTLSISDNGKGMDDKTKELLFERYYRGTNTEESN-IGTGLGLAITKQLVHAHNGAISIDSELGKGTTIILVFPFCS. 580
35 -68.500IDP04148 gene: basS; two-component system sensor protein [Yersinia pestis CO92] YPO3508 [Yersinia pestis CO92]  ali follow..  20  37...........................................................................FLVDETLSAKARNEQVDKEIAEAIASLLAPSLIMMTITLLLSFWAISWIIRPLDQLQQKLAERSADNLSP-------------------LVVNSEMQEIVSVTSTLNQLLLRLSNTIQQERLFTADAAHELRTPLAGIRLHLELMEKQG-------IAESKSLINRIDLLMHTIEQLLMLSRAGQNFASGHYQTLDVNDVVPPLQEELAEMCELRRQTIELPPHAKMEGDATLLRLMLRNLVENAHRYSPVGSQIIVTLSTE-NQGVLLQVTDEGPGIKQNQAGELTQAFRRMDQRY----GGSGLGLNIVIRIAQLHQGKLTLENRLRTGLKAQCWLPATTY 352
36 -68.300IDP04678 sensor histidine kinase [Bacillus anthracis str. `Ames Ancestor`] GBAA2560 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  22  57...............................................................................IRIFGYEKYKGIKESLMMIVSYLFLFSIFSSYLYIFYRHERKLYYETCIKKMIEEIRYIANGNFNHKVSI-------------------VNHNYLEELASGVNQIVEQLKVSIDEERQLITNVSHDLRTPLTSIVGYVNLIHHDNYRDEVELRHYIQVIYDKVTRLNALMNDLFEYTRVQNKELSLYSVPIDIVELLGQLTVQFRIQLQEANIDCRPSKKLMVLADGDKLVRVFENLIINAIAYGNDGDYIDITAYEN-NNMIAIDITNYGQPIPSTDLPHIFERFYRVEKSRSTNTGGSGLGLAIAKSIVELHKGTIEVYSD-DKKTTFTVKLQPYK. 384
37 -68.200IDP04343 two-component system sensor kinase [Yersinia pestis CO92] YPO2916 [Yersinia pestis CO92]  ali follow..  19  161...............................................................................TRDVIFSRGQQLQKDIAERGQFFGWQSLLLFLVSVLLVVLFTRMIIGPVKGIERMINRLGEGSLGNTALF-------------------KGPRELRSLAQRIIWLSERLAWLESQRHEFLRHISHELKTPLASMREGTELLADEVAGPTQDQQEVVAILDHSSRHLQQLIEQLLDYNRKLADG-PGEPEHVDLAEMVGNVISAHSLPARAKMIRTETEDARICWAEPTLLMRVLDNLYSNAVHYGEESGTIWICSRQV-NDRVQIDVANTGAPIPTSEEIMIFEPFFQGSHQRKGAVKGSGLGLSIAQDCIRRMQGDLQLVTVDYAAVCFRIELPLTAE 481
38 -67.700IDP04247 sensor histidine kinase [Clostridium perfringens ATCC 13124] CPF_1402 [Clostridium perfringens ATCC 13124]  ali follow..  17  83.......................GGWIEIIDKDLNIIETIGDQKVKRDNYSSEEFSKILVDEMHGVNI-RFFVITRIPEENFGKMFTRNPKIGFKIFVYIMISLYIFIFTMSLILYSKLTSKTFTKPLDKLMNGVRKLSLGDYSTRINI-------------------EKNNEFEELGEAFNNMASKIEEEKKLRKEFVRNIAHDLKTPLSSIIGYSNIIKNNPDIEKESLHKYISVIENNGERANEMIMELFEFYTLQSSEFILHKKYQDLSEFLRNLIADYIYLLEEKDFDFDFEDDLYLEFDNKRLERAIGNLIINSVKYNKKGTKFLISLKKEGD-KVKIIVSDDGIGLSEEIKKHIFNPFVREEKSRNSKKGGSGLGLTISKEIVEKHGGTIYLSDGPLKGCNFVIELPIK.. 478
39 -67.000IDP04692 sensor histidine kinase [Bacillus anthracis str. `Ames Ancestor`] GBAA5105 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  22  41.................................................................................MVRYEEPLAQFRSIVREFGDINFFLIFFIPLSIIFFFFLTKPYLKYFSEISNGIHHLANGNFTNRVQV-------------------SSNDEFGDIAREINVASEKLKEAVERKDQLVVNLAHDLRTPLTSVLGYLDLILKDENLTKEQIKHFSTIAYTKSQRLESLIDELFEITRMNYGMLQLNKKPIDISELLIQLDEELYPLLEKHHLEANVDPHLPINGDGKLLARVFENLLTNAVRYGYDGQFVDLNGYIDNE-EVVVQVMNYGDSIPEEDLPYLFDMFYTGDKSRTENRGGTGLGLFIAKNIVEQHNGTISAESNVV-RTIFEVRLPKDKK 365
40 -67.000IDP04430 sensor histidine kinase [Bacillus anthracis str. `Ames Ancestor`] GBAA4921 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  18  64LKTAAKKHQSQLLDESFVSSLEKEGVKIVVRKGETISYATKVFESVALPKFESANINSRGTTELGDTFYRYVKFDFYFPGSIFVLKKQSSFVDLTQKLFILFVSLLLLAILLIGLLSYLVSRSVIKPIFVLKDATGKIKEGNLDFHIPV-------------------TSHDEIGQLNQGFEEMRKKLKESIEMRKELISNISHDLKTPITSIIGYVEGIKDGVANTPEKMDKYLTTIHTKARHMDTLIDELFLFSKLDLNRVPFQFETVELNMFMQELIEEMQMDLSKEGIEVNLQSPLYVTADCEKINRVISNLIHNSVKYMKEEKKITVTVSSDNN-KVIVKVMDNGSGIESDTLPYIFERFYRAEQSRNSSTGGSGLGLAIAKQIIEEHGGNIWAESELGEGTSIFFSLEKVEK 481
41 -66.600IDP04659 sensor histidine kinase [Bacillus anthracis str. `Ames Ancestor`] GBAA0272 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  17  110.......................ALKILVTDESGKVLYKTKQAQEEQIDLHNTINYSNGRDVFENTRKEFIAFSPITIEDKNLYMFVSGIPDGVVMYDTQEGPFPFLIGVLVFIFSFFYITKRKMKQIEAMAEGVKEIEKGNLAYRIEK-------------------KGEDEIASLTENINNMAEELMNNIEKENELITNVSHDLRTPLTSIMGYLRLLRDSKYENKEQHDEYTRIAFAKSEQLKNLIEDLFEYTKLTNEQVVLEKQEVCVNELLEQLIEELVPQAEEHGLTFVKEERAYAAIDSEKMVRVFDNLLMNAIKYSKDDGEIKVSLQRQ-RWEIQIVIANHSEEFTREELASLFERFYKKDQSRSRVTEGSGLGLAIAKSIVELQGGSIRAEYK-DGIIQFIVSLPIIER 501
42 -66.600IDP04672 sensor histidine kinase [Bacillus anthracis str. `Ames Ancestor`] GBAA1482 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  25  264...............................................................................EYAFAIASLQPVNEAMLVLKDYYVYALIIVFLVIILLSFYYSKIIVKPLIKINRVTKKMANFDFSEKLPV-------------------TADDEIGGLSGSINTLIERERQLEKTRKEFISGVSHELKTPLSVIRSFAEGIKDGVSKDTT---YYTDVILEETENMNRLIVEMLELAKLESGTYKLDMTTFSIGELIQQVYTKLLFSMEEKHLQVDVNSSIFVKANRSRIEQVVVNLLSNAIRYTPEGEKIQVSV-ITMEDTVKIEIENTGNPIPEESLEKIWDRFYRLDASRSRHTGGTGLGLSIVKNILDLHHAEYGVYNTTN-SVVFYFNLQKVKE 601
43 -66.400IDP04358 gene: creC; putative histidine kinase sensor [Yersinia pestis CO92] YPO0895 [Yersinia pestis CO92]  ali follow..  17  92.......................EYRVYLTDTDGQVIFDSSGRALWLTLRGEYGARSSRTDPDDAESSVMYVAAPVIVEGVLSIGKPNLSMVPVIKRSERKILFAGGLLLGIALLIGLGFVWWINRAIGKLVDYAERVAEGQAVA----------------------AMGSSELNDLALALESMRLKLDGK-AYIEQYVHTLTHELKSPLAAISGAAELLRES--PPPETAQRFLINIEQQSARIQQLVDKMLVQARLESR-VDLQLSPLEISHILKQSFSAKEAQAVSRGVTLRLKDNAMLIGDGLLLSQALNNLIDNALDFTPAGGEISVSGERQ-DDTYLITVEDSGSGIPGYAQEKIFDRFYSLPRANSV--KSTGLGLNFVREVAAIHQGSICLENRLPQGVSARLTLPL... 472
44 -65.900IDP04104 gene: rstB; two-component regulatory system, sensor kinase protein [Yersinia pestis CO92] YPO2309 [Yersinia pestis CO92]  ali follow..  22  106..............................................................................RSHYVLAVGPVPYLFYLHQMRLLDLALLILIGLSLALPVFLWMRPHWKDLLKLENAAQRLGSGHLDERTHF-------------------DPTSSLSRLGVAFNQMADNINTLIVSKKLLIDGIAHELRTPLVRLRYRLAMSD-------NLTESEQQALHHDIGQLEALIDELLTYARLDRPQVSLNLEPIDLPAWLTTKIMDIRSIHQEREIELDIPRGDFGAVDLRLMERVLDNLVNNALRYSHQRLRIGLWF---DGDNACLQVEDDGPGIPPEERTRIFEPFVRLDPSRDRATGGCGLGLAIVHSIALAYQGSISVNTSPLGGASFRFSWPIKTH 417
45 -65.300IDP04132 putative two-component system sensor kinase [Yersinia pestis CO92] YPO2997 [Yersinia pestis CO92]  ali follow..  20  138.......................................................................................ANAPDKHRREILNVPIPMIWMGVLGGLFFSTLLAWNLTRPMRQLRVGFERVAQGDLSVRLL----------------PVMRRRHDELTEVARDFDSMAERLQALVSAREQLLHDVSHELRSPLARLQLAIGLAHQ----NPDNVDNALQRIEHESERLDKMIGELLALSRAENHSLADDDEYFDLQELVKVVVNDARYEAQLPGVEIQLESEYTVKGNAELMRRAIENIVRNALRFSASGQQVKVTLSAL-DKRYQIQVADQGPGVEENKLSSIFDPFVRVKSAMSG--KGYGLGLAITHKVILAHGGQVEARNGEQGGLVITLRVPRWQ. 448
46 -64.400IDP06113 histidine kinase sensor protein [Helicobacter pylori J99] NP_222872 [Helicobacter pylori J99]  ali follow..  17  111.................................................................................LLKKDEHFVLYKDLHSVSYRNYFLAITVGLLLILFLFLFVLQSLLPLRELRSQVKRFAQGDKSVSCKS-------------------KQKDEIGDLANEFDNCIQKINAMNESRVLFLRSIMHELRTPITKGKILSSMLKE---------ELSCKRFSSIFDHLNMLIEQFARIEQLASKNYGSNKEKFLMSDLIDKIEKMLLIDEDKKSPIHVSSSNYIIEADFELFAIALKNMIDNAIKYSDDKQ-VFLDFIGNN-----LVVSNKSKPLK-EDFEKYLQPYFKSS--NPSQAHGFGLGMYIIKNALEAMGLNLSYHYSNG-RICFTIHDCVFNS 409
47 -63.900IDP04630 gene: qseC; sensor protein qseC [Coxiella burnetii RSA 493] CBU_1228 [Coxiella burnetii RSA 493]  ali follow..  17  103.....................SNHSEFQIWNNQGKLLLHSAGTPTIPFSNGNEG----LSTLWLHGESWRVNTLYDPATETFMVAERSNYRQQLENQLTQDSIFIMLITYPFLGFLIWIIVGRGLDTLKKVAKEVRHRAPAYLEP-------------------VDLEAVPSEIEPLVSELNNLFGRLKEAFEREKRFTADAAHELRTPLAALNTHTQVALR--AKTPEERKEALLKVLAGVNRGTHVVQQLLTLNRMVPEATLHEQNWMDLGKEAADIAAQLAPEAIAKNIDLELIDPPKVKGNNTAISILIRNMVDNAIRYSPEKSKVTIRIEKE-DNRVILRVIDNGPGIPEELRERVFERFFRMIGNQAT---GSGLGLSIVLQIAKLHNAEIALKTPNGKGLDFWVTFPLIHN 475
48 -63.400IDP91948 histidine kinase PnpS [Streptococcus pneumoniae str. Canada MDR_19A] SpneCM_010100000392 [Streptococcus pneumoniae str. Canada MDR_19A]  ali follow..  23  16...............................................................................LILIAGMALTWISKGIGLFLLALSLGLGGYWLFC-------LWKWEVAFETLHQPL-----LTSSEYFLE-------------------KGQEDLKSLAQYVSGLKTKVSQQDQQNLAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLLTLSKAQQMP--IQWTTLSLAEFVQDLTQSLQPQLKKKDLQLQVPDDVTLVSDSQLLSQILLNLLSNAIRYTEQGGKIEVKTQKV-NEGIKISVSDTGIGISQLEQDRIFERFYRVNKGRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSF 440
49 -62.900IDP02394 gene: phoQ; sensor protein PhoQ [Yersinia pestis CO92] YPO1633 [Yersinia pestis CO92]  ali follow..  22  172.................................................................................IVVVDTIPQELQRTDLVWNWFSYVLLANLLLVIPLLWLAAYWSLRPIKALASQISQLEKGEREQLDE--------------------NPPRELQSLVRNLNILLMNERQRYTKYRTTLADLTHSLKTPLAVLQTTLRSLRTGKQTTIE---EVEPIMLEQISRISQQIGYYLHRASMRSEHNVLGREIHSVPALLDSLYSALNKVYQRKGIALTLDPEVTFLGEKNDFMEVMGNVLENACKYCLEFVEVTTL---HSEKQLTIVVDDDGPGIPENKRQLIFQRGQRVDTLR----PGQGLGLSIAAEIIEQYQGKISITESPLGGARMMVTFGQQQD 480
50 -62.400IDP04556 putative two-component sensor histidine kinase [Yersinia pestis CO92] YPO3008 [Yersinia pestis CO92]  ali follow..  17  11.......................TSITFLICAAIAYFGYRSLTHETLLRHYQNQRLAQSHTTQVSTFILDLLNQ--NAVRLGSLVSYIQLDNASLNALIAQESSIDALFVLNTQAALTEKEKAWIQAITPIIQDPSLLYSHHYTDEQTRPTSGWYLSRELSDPLLIYWQARDNQKVPYVKLLSDYNRQLRLAQQQVSFVGQVSHELKTPLTNITLYAEMLQELQPEQPTAEQRYLEVILNESQRLSRLIQNILSFTKAPK----LHLQTVALRPLLNKIYHTFIPAFSAKNMELIINTDIHLTTDVDRLTQIISNFLSNAEKYASQGKRVELIGEQA-DDRVLIHVRDYGNGIAAKELKAIFQPFYRVKSHITEGVSGTGIGLTIASQLAASLQGEISVTSNPA-GSCFTLKLPMTIK 503
51 -62.000IDP04481 gene: nmpB; phosphate regulon sensor protein PhoR [Yersinia pestis CO92] YPO3204 [Yersinia pestis CO92]  ali follow..  30  194........................................................................................................................................................................................VTQMRQLEGARRNFFANVSHELRTPLTVLQGYLEMMHDQELAGPL-RDKALGTMQEQTKRMDGLVKQLLTLSRIEAAPNVDLNERVDIPLMLKILQHEVQALSNGREITFRVNDQLKVFGNEDQLRSAVSNLVYNAVNHTPEGTKIEVCWQQTPQG-AQFQVSDNGPGIPPEHVPRLTERFYRVDKARSRQTGGSGLGLAIVKHALSHHDARLEVMSEIGLGTRFIFTLPNRL. 425
52 -61.600IDP04133 gene: hpkA; sensor histidine kinase [Clostridium perfringens ATCC 13124] CPF_1195 [Clostridium perfringens ATCC 13124]  ali follow..  21  3.....................................................................................................................LIIFILKTKEINRLTLELKKLNSEGKIEKL------------------RLSLPNKNIENLIVEINTLIDDKRKMENIYREAIANMSHDLRTPLTSIMGYVYLLND-DKLDKEERKEYLKIIEKRSLVLNDLITNFYGLSRIQADQYEIKLEPVNLELVLGEIIAAFYETLDYKFGEPEIEGLGPVLGDKQALNRIFTNLIENIIKHGEGEVKISL---KKKNKYIVMEFSNKAEELEPKDVNRIFEKFFTKDRMRTG--QNTGLGLAIVKLLVEKQGQKIEAKKV-GNRLVINIIWSLES. 287
53 -61.500IDP90007 gene: qseC; quorum sensing Escherichia coli regulator C [Escherichia coli O157:H7 EDL933] Z4378 [Escherichia coli O157:H7 str. EDL933]  ali follow..  19  83.....................DDALTFAIFTHDGRMVLNDGDNGEDIPYSYQREGFADGQLVGDKDQWRFVWMTSPDGKYRIVVGQEWEYREDMALAIVAGQLIPWLVALPVMLIIMMVLLGRELAPLNKLALALRMRDPDSEKP-------------------LNATGVPSEVRPLVESLNQLFARTHAMMVRERRFTSDAAHELRSPLTALKVQTEVAQL-SDDDPQARKKALLQLHSGIDRATRLVDQLLTLSRLDSLDNLQDVAEIPLEDLLQSSVMDIYHTAQQAKIDVRLTQGIKRTGQPLLLSLLVRNLLDNAVRYSPQGSVVDVTL-----NADNFIVRDNGPGVTPEALARIGERFYRPPGQTAT---GSGLGLSIVQRIAKLHGMNVEFGNAEQGGFEAKVSW..... 449
54 -57.500IDP04272 lantibiotic biosynthesis sensor histidine kinase, putative [Bacillus anthracis str. `Ames Ancestor`] GBAA3899 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  17  53.KQIESQRDAIVKAEQEDDQILKQYKYALYDFSGNVIQGSINKDYAGQIWNNIHNDEKGDSKYYYAIIERDKDICVILYTLHATFKNPILQKYVPSPEVCEIVLFILLFVAEVIFLSRSFGKSLSKEMMILRKVTDKIQKEDLDFQVEQ-------------------SKIKEVNEVLTSLVKMKDELNHSLRTQREQIAALAHDIKTPLTILRGNAELLNESMLDSNQ--KKCNEHILKSIDEMEIYMKSLLDITKCEEG-APLQFMQTDLRDFIHNIIEESAICVLGKQLNLIEDIPNFIPIDETALKRAIMNIMMNAIEYSPTKGDLMFSVEMI-SEKLQFIVEDSGRGFTEEEMHSATEQFYRGDKSRNAK-DHHGMGLYIAKSFAKQHGGNLYLSNEKLHGAKVVLEIS.... 452
55 -57.200IDP91358 Signal transduction histidine kinase [Vibrio vulnificus CMCP6] VV1_2848 [Vibrio vulnificus CMCP6]  ali follow..  17  87......................SGLYWTATINNQTLRSRSLWDRTIQIK----QGPIRKTVLGAKNERLIVLEQDVFLPEYIVIGMDEAPMKSTLDHLTGQLWMILGLLFVGVMTVIGLQIAWSFRPLGKLQRELKALRAGSQQQ----------------------ASYPAEVSPLIDDLNALLFHYQELLQRARNHAGNLSHSLKTPLSVLRNEISQLDV----------ESSHKLLPPVEQIQQHIDYHLGRARMAGSM-NILSVKSNPSERVDAISIAFDKVYAERDLLLELDSELEVAVDQSDLDEMLGNLLENSYKWARSQIRVHSTL--TSDDQLTLIIEDNGPGIAEEHLTQVLKRGVRLDETTP----GTGLGLNIVAEMAYSYRGDLTLERSQLGGLRANLTLKLAAK 448
56 -57.200IDP04431 sensor histidine kinase [Bacillus anthracis str. `Ames Ancestor`] GBAA5088 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  18  39.....................................................................................................FVVLSLYLFICFLAYRYVRNRRMYHRLSEQPEKMEDAFIERATAPMPHGV-------------------NELVRTQYRLFQKELQSYEVKQQEHQLFINHWVHQMKTPVSVMQLMVLEMED---------EHLIPKFKKELERLNQGLDMALYMARLNNFHEDFHVETISLKDTVTKNINGLKELFIRNGVVLEVHSDLKVASDAKWLKFIIYQLMTNAVRYSGERGKKVFLSAYRNGKDIILEVRDEGVGIPQEDIRRVFEPFYTGKNGRTFG-ESTGMGLYIVSKICDYLGHSVKLDSEVGKGTTIKIIFHNAAN 328
57 -56.300IDP04236 sensor histidine kinase [Clostridium perfringens ATCC 13124] CPF_0837 [Clostridium perfringens ATCC 13124]  ali follow..  19  38.....................................................................................................IFLIGCFWFIPLFTYIILDFYKSKKFYDNISITLDKLDRKYLLPEVIEEPNFYHGKF------------YEVLKETDKDMHEHVKKYILEQKEYREYIETWVHEIKTPIASTRLILE----------NNESESSENIKKEIKKIEEYIDQALYYARSTDVSKDYIVKEFSLGKSVRNVIKKNSRDFINKRIAIYLELDYKVYSDEKWVEFIINQVINNSIKYSSKNSRVKIFA-NKSKNSITLKIKDSGVGIPNKDLGRVFEKGFTGENGR-RFTKSTGMGLYLCKNLCDKLGLGLKITSKENEGTEVSIIFPIGD. 331
58 -54.000IDP04382 sensor histidine kinase [Clostridium perfringens ATCC 13124] CPF_0116 [Clostridium perfringens ATCC 13124]  ali follow..  18  41.....................................................................................................IVIINEAGILIYHIFDYLRKKQYYNEIKENMESLDK--------------KYLISEVIEEGTFTESKLIYDVICKGNKAMNDEIGEFKRGINDYREYIELWVHEIKTPIATCKLLIE----------NNESPLTESIGEEVCKLENYIDQALFYTRSNTLEKDYIIKEMSLSSCVNKVLNNNADSLIKKRVKISLGLEKQVYSDSKWIEFILGQIISNSIKYMNEHKELKIYC-NENSKYVILNIEDNGAGISEKDISRVFDKGFTGENGRKFG-KSTGIGLYLCKKLCKKLGLDIKLISEEGKFTRVSIIFPINR. 332
59 -53.700IDP04327 sensory box histidine kinase [Clostridium perfringens ATCC 13124] CPF_1243 [Clostridium perfringens ATCC 13124]  ali follow..  22  329....................................................................................................................................................................NSIKNENGESIRRIIVINDITDTIEKSNEMEKEFFANISHEFKTPVNLIYSALQLLELKLKNNEESYINYIKMAKQNVFRLLKLINNLIDSTKLEAGFFNVNIKNHDIVSCVEDITMSICGFAEKNKISITFDEEKIIAFDLNHLERILLNILSNAIKFNRENGNIDVYM-SFDERYANISIKDTGIGIQKDKIDLLFHRFKKINNRLTKVNEGSGIGLFIAKELVKINGGEMRVNSELGEGTEFIIKLPIKK. 590
60 -53.100IDP04341 putative aerobic respiration control sensor protein arcB [Coxiella burnetii RSA 493] CBU_0634 [Coxiella burnetii RSA 493]  ali follow..  26  235...........................................................................................................................................................................TERKQNEQKLIEAKLQAELSDRAKSEFIANISHDLRTPINGILGIAQIFNMHEHTKKQ--EPLINDLSASANLLLGLVEDILDFARLEVGKLELKYSTFNLRQLVTFLVKTFSFQTQQKQIKINVY-PDSIVSEPNYIRRIFLNLIGNAVKFTEKGQDVTVNLEGNKPAMLKILVKDTGIGIPKDKLNTIFDRFSRATPVYSSRYEGLGLGLSIIKRLLDNLGGEVHVSSIENEGSTFTLTIPCE.. 482
61 -52.800IDP04183 sensor histidine kinase [Vibrio cholerae O1 biovar eltor str. N16961] VCA0257 [Vibrio cholerae O1 biovar El Tor str. N16961]  ali follow..  17  219........................................................................................................................LPFTLEPYQAHKPCDERYSNLCFNQRVSSHALLYSGLVI------------GVLLAFGAALRSLWLRYQEG-RERRFILQLLTHELRTPITSLGFTVESLRSQFDELSPKAQESLWRLMADHQRLAQLSETSRHYLSPSHDT--MARHPAQLSDFIEHCIEGFE-------VELHLKHDSILALPYYWLGLCVTNLLSNAKQHGVPPIRLTVSV---VAQTLRIEVEDCGEFP--SFYQRLCKRLSRHQDTHSRNTDNMGVGLQLVRKLITQMGGKLVIRRH---PTRCILELPL... 484
62 -52.400IDP04043 sensor histidine kinase [Vibrio cholerae O1 biovar eltor str. N16961] VCA0565 [Vibrio cholerae O1 biovar El Tor str. N16961]  ali follow..  18  282........................................................................................................................................................................................WNSKRQEMRSRMLILQILTHELRTPIASLSLTVEGFRREFEHLPESLYDEFRRLCEDSRRLRQLAEASKDYLQSDSKPLAS-----DWVPSVEEWLQYKVEEEFSGNVTLKLNQDIAAKLNVYWLGTCVDNLLRNAVKYGVAPVTLEVI---TQTNLVTFKVTDQG-SLTHRDWRHLRKPFVSK--------SGLGLGLTIVESMVGRMGGKMSLE---GPPTTFILEIPCETD 495
63 -51.700IDP04505 sensor histidine kinase [Vibrio cholerae O1 biovar eltor str. N16961] VCA0531 [Vibrio cholerae O1 biovar El Tor str. N16961]  ali follow..  22  203..............................................................................................................................TLVDRGTILGVIYFLRYPHERFASPEALRRESKIAPWVRSLLTLSLARAHAHRTLAH-VEAEKQLESTRTTLLASVSHDLKTPLGAIIGSATTLTDPSLHSTETQQELLTSIAEQGERLNRSLTKLLDITRYTASALVPKLDWVEPEELIGTVLSRLAPRLTHHKVQIE-SQPMLVELDSLLIEQVLINLVENAAKYTPRGSEIEIACAYQ-EQQFTLAVMDNGAGIPDEALPRIFDRFYRVEGNHA---DGTGLGLAICQVIVAAHQGSIRVHNRESGGACFTVTIPCRQY 489
64 -51.500IDP04680 sensor histidine kinase, putative [Bacillus anthracis str. `Ames Ancestor`] GBAA3066 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  15  42........................................................................................KNIPFHESYAYPTMLIIFLLSLLVLAFVFSRSINTVLNKINILNQTIRDLASKKIPNIIDV-------------------KSDDEMGELIKSVNLLIERTQQQEQIKKELLNKLRHDINTPLTAVRLQLYYL----EGEYKGQAPVLESLYEQIQYISDLTNEFNMQSTETLENTYIVHDEVNIHNLIETMIKKWSYLYSIHKIELVYDKELIWNSNELWIQRLFDNIFQNVLKHSK-AKKLKIII-----DEDIVYFRDNGIGFDINS-------------------KGTGLGLKNIEDISKMFDIKYTLQSN-SEGTMFSFENTQKN. 332
65 -49.800IDP02415 sensory box sensor histidine kinase/response regulator, putative [Coxiella burnetii RSA 493] CBU_1761 [Coxiella burnetii RSA 493]  ali follow..  21  105....................................................................................................................................................................VPYRNKEGNIVGILGIYTDITKRLRKANKVKSEFLANMGHDLRTPLTGIILIAEYLWKKQTEEKD--KQLSKDLILAGKQLLHFINEVLEITNVEAGNIDYEKKSFSLKKLIDQVFAMLRPSFQQKQLAFYND-PEVLIGSEIMIFRILMNLLGNSLKFTEEGQTIQTKLANRSGNQVLIIVSDTGIGIPKEEHKNIFAQFKRLTPSYASKYRGSGLGLFLVKTYAEALQGQVTLESEPGRGSRFICTIPLT.. 367
66 -49.300IDP04515 putative sensor histidine kinase [Clostridium perfringens ATCC 13124] CPF_2673 [Clostridium perfringens ATCC 13124]  ali follow..  22  276......................................................................................................NRYLWIIPIVLVIHFIVKFIRKYDGLDTVIKGIEKVKKGDTDIEIKD-------------------NDDRQIRELADDVNDLRLGYKELVEEGTELISNVSHDLKTPLTSIINYVNILQL-NNIKEEERKEYIEILDKKSQTLKKLIDDLFEVSKMSSGKVELFKYNIDIIQLVYQCIAEVEDVYSEKEIEFNGPEECMVKIDPQRMSRVFQNLTTNALKYSLEKTRVYVEI-KDLENYVEISFKNISSYALDFDEKDILERFARGDESRNSTIEGSGLGLAIAKTIVELHNGKFRVECE-GDLFKAFVIIPKNKD 578
67 -48.200IDP04164 sensor histidine kinase/response regulator [Vibrio cholerae O1 biovar eltor str. N16961] VC1445 [Vibrio cholerae O1 biovar El Tor str. N16961]  ali follow..  25  188..........................................................................................................................................................................QKLVEIRTRELRLAQKLAEQANQSKSNFLAMMSHELRTPLNAVLGLIDILRG---ESTSYQVELLEQMENSAELLLIIINDILDLSRIESGHFSLHCHWLDLEKKLDQSLVYHRQIAQDKGVHFYVQ-TLEYYTDSARLTQILFNIVGNAIKFTKQG-QVDVVLDYTKDG-VVFRVKDTGIGIEKNRVEQLFTPFIQADNSITRNYGGTGLGLAITKHLVELMGGTIQVESEFGIGTTFTLYIPLQS. 433
68 -47.900IDP04543 sensor histidine kinase/response regulator [Vibrio cholerae O1 biovar El Tor str. N16961] VC2453 [Vibrio cholerae O1 biovar El Tor str. N16961]  ali follow..  16  61LRMQSRESVRRIISYAHRKNSKLVRSIAVFDANHELFVTSNFHPNFEKLMYPKDKPIPFLSSSVIDENTLILRTPIISEGYIAIELDLSSLRLQQYQEIFSAGLVLVIGILLSGVFASRLMYDVTRPITHMKNMVDRIRRGHLDVRIEG-------------------KMHGELDTLKKGINAMAVSLQEAARVKSEFLANMSHELRTPLNGVIGFTRQMLKTQLTNSQ--ADYLQTIEKSANNLLTIINDILDFSKLEAGKLALENIPFEFQEVLEEVVNLQATSAHEKGLEIDPKIPRGVVGDPLRIQQVLTNLVGNSIKFTERGNDVSVEMRALRDDVIDLMVRDTGIGISERQQAQLFQAFSQADASISRRYGGTGLGLVITQKLVSHMGGEISLTSRLHQGSTFWFTLRLHTT 519
69 -47.800IDP04550 sensor histidine kinase [Clostridium perfringens ATCC 13124] CPF_0460 [Clostridium perfringens ATCC 13124]  ali follow..  19  446......................................................................................................IFGVVIYSGILFYFGRKYIDKWKKDYNKILEKTKEISNGNLDSKDDE--------------------DCGFFNPMRDELNNIQKGFKAAVDEETELISNVSHDLKTPLTSIIAYVDLLKG--EEDEEKRKAYLETLERKSQRLKHLIEDLFEVSKATTGNINLNIMDVDISYLMKQVVLELDDKINEAGLDMRLEEKVILPLDGQRTYRVFENLIINVVKYALPNSRVYIDI-KEGRENVDVIIKNISADEITFNINEISDRFVRGDKSRN--TEGSGLGLAIVKSFVELQGGKFHIEVD-GDLFKAIISFKKK.. 743
70 -47.500IDP04227 sensory box histidine kinase [Clostridium perfringens ATCC 13124] CPF_0198 [Clostridium perfringens ATCC 13124]  ali follow..  24  508............................................................................................................................................................................NLTSKKRLENLAFKEAKAYEQIRNEFFANISHELRTPLNIIYSTIQLLNSKHETDPNFYDKYKQGLKINCYRMLRLINNLIDVSKIEVGFLKADFTNRDIVFLVENIVSLVIPHSENKDINIIFDEENIIKCDPVKIERLILNLLSNAIKFTQNHGEIFVDLNISKD-WVKISIKDNGIGIPKEMQASIFDRFVQADKSLKRRNEGSGIGLSIVKSIAELHDGKIELISDGIKGSEFIVWLPNVK. 760
71 -47.300IDP04365 sensory box histidine kinase [Clostridium perfringens ATCC 13124] CPF_1523 [Clostridium perfringens ATCC 13124]  ali follow..  21  510...............................................................................................................................................................................REIEILKNKFEEIKQYDKVRSEFFANLSHELRTPINIIYSCIQLLNTSKKNKANLYDKYEKTLKQNCFRMLRLVNNLIDITKIDSGFIKMDFINYDIIKLTEDITMSVIPYVESKNIDIIFDEELEIRCDPDKIERIILNLLSNAIKFTEPGGKIEVSI-FADETWVDIRVKDTGIGIPSHMKEFIFERFIQNDKSLNRNKEGSGIGLSLVKSLVELHEGKVFLRESNESGSEFSILLPNVK. 756
72 -46.900IDP04484 gene: barA; two-component regulatory protein [Yersinia pestis CO92] YPO3381 [Yersinia pestis CO92]  ali follow..  19  86..........................ISVFDVDNKLFVTSNYNYNSSQLRLPPGEPVPDSLMLSYRGDSLILRMPIVSEGYIAIDLDLQSVRLKQYKEIFISTLLLLFCMCVAILFAYRLMRDVTGPIRNMVNTVDRIRRGQLDSRVEGHMLGELDQQNIDQATSDLRETLEQMEIQNVELGLAKKRAQEASRIKSEFLANMSHELRTPLNGVIGFTRQTLKTSLTPTQ--TDYLQTIQRSANNLLCIINDVLDFSKLEADKLILEHIPFSLRETLDEVIILLAHTAHEKGLELNNDVPDQVLGDAMRLQQIVTNLLGNAIKFTEEGNDILVVVKAIASQQVTLEIHDTGIGISESQQAQLFQAFRQADASTSRRHGGTGLGLVITERLVKEMGGNISFQSQMSCGSIFRFHLTLELN 520
73 -46.900IDP02181 two-component sensor/regulator [Yersinia pestis CO92] YPO0256 [Yersinia pestis CO92]  ali follow..  18  222............................LLDKNGELLPISQQATSSNQLHEILNQLKNSKLHDGWQQTPDYLVLRTQLKGPLVIYPRMGFAWEALKPALYQLPFALAILLLLTSVLSLLLRYYLAIPLWNFINIIGATGPQAMEPRLPI-------------------NRIDELGHIARAYNNLLDTLEQANRRKSDHLTTISHEIRTPLNGALGAVELLQNTPLDAGQ--MRLAETAHQCSLSLLAIINNLLDFSRIESGQMTLSLEKTALLPLLDQAMLTIHSQALSKSLALSTF-PLELELDTLRLRQILVNLLGNAVKFTPQG-RIQLRVRRQNQ-TLCFTVEDTGCGIDVQHQQTIFQPFMQT----SDHEQGTGLGLAIADNLAKMMGGHLTVFSEPGQGSCFSLCLPFN.. 615
74 -46.600IDP01908 gene: ssrA; sensor kinase [Salmonella typhimurium LT2] STM1392 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  21  287...........................................................................................NRILKIILQQIPFTLTALVLMTSAFCWLLHRSLAKPLWRFVDVINKTATAPLSTRLPA-------------------QRLDELDSIAGAFNQLLDTLERANKRKSIHLTVISHELRTPMNGVLGAIELLQTTPLNIEQ--QGLADTARNCTLSLLAIINNLLDFSRIESGHFTLHMEETALLPLLDQAMQTIQGPAQSKKLSLRTF-PLYFHTDSIRLRQILVNLLGNAVKFTETGG-IRLTVKRH-EEQLIFLVSDSGKGIEIQQQSQIFTAFYQADTN----SQGTGIGLTIASSLAKMMGGNLTLKSVPGVGTCVSLVLPLQE. 614
75 -45.900IDP04569 sensor histidine kinase [Clostridium perfringens ATCC 13124] CPF_2242 [Clostridium perfringens ATCC 13124]  ali follow..  22  374...............................................................................................................................................................................KFSEKIKDNLRKRTLSEQIKNDFLSSISHDLKTPINVIYSSVQVQEKFYSNEIKKVDYYNQVNKENCMTLLRLANNLIDSSKIDYDYLKPNFKIYNIVTLIEDSIGNLAEYIKEKNLTYVFDEEVYVNCDQEFIQRIILNLISNSIKHTREGG-IGVEI-KAKKSKVIISFTDTGEGMDKEFIEKAFLRYSKGNKKGVKN-KSTGIGLYIVKNLVELQNGTININSIKDTGTNIRLEFSREK. 616
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Damiano JS, Stehlik C, Pio F, Godzik A., Reed JC. CLAN, a novel human CED-4-like gene. Genomics. 2001 Jul;75(1-3):77-83.