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Query: IDP04504 2-dehydropantoate 2-reductase [Vibrio cholerae O1 biovar eltor str. N16961] VC2307 [Vibrio cholerae O1 biovar El Tor str. N16961], from CSGID

Results of FFAS03 search in CSGID
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MNIVVLGPGAVGSLWALHLHSAGHQVALWSRQAQPTITLQLDEEAPISFRNQNLDTLIHADLLLITVKAWQVEAALQPLLPHLNRETILLFMHNGMGAVEAISESLTHFPVLFATTTHGALKATLNQVSHTGFGQTQVGPFNALGARCDFIADVFNHALAPVTWNPEIQQALWRKLAVNCAINPLTAIHQCANGALVAPEFTPIITAILDEVTAVMQAEAISGEAEALRDGVYQVIQATAANLSSMHQDVFHRRPTEIDFITGYVVRKGEQHGIATPVNSALYQQIKTLEQSWSKALast
1 -99.900IDP04504 2-dehydropantoate 2-reductase [Vibrio cholerae O1 biovar eltor str. N16961] VC2307 [Vibrio cholerae O1 biovar El Tor str. N16961]  ali  100  1MNIVVLGPGAVGSLWALHLHSAGHQVALWSRQAQPTITLQLDEEAPISFRNQNLDTLIHADLLLITVKAWQVEAALQPLLPHLNRETILLFMHNGMGAVEAISESLTHFPVLFATTTHGALKATLNQVSHTGFGQTQVGPFNALGARCDFIADVFNHALAPVTWNPEIQQALWRKLAVNCAINPLTAIHQCANGALVAPEFTPIITAILDEVTAVMQAEAISGEAEALRDGVYQVIQATAANLSSMHQDVFHRRPTEIDFITGYVVRKGEQHGIATPVNSALYQQIKTLEQSWSKA 296
2 -19.700IDP01976 gene: gpsA; glycerol-3-phosphate dehydrogenase (NAD+) [Coxiella burnetii RSA 493] CBU_1518 [Coxiella burnetii RSA 493]  ali follow..  16  7.PIAILGAGSWGTALALVLARKGQKVRLWSYESDHVDEMQAEGVNNLKAYCDLKASLEGVTDILIVVPSFAFHEVITRMKPLIDAKTRIAWGTKGLAKHEVVATELGQVPM--------AVISGPSLATEVAANLTAVSLASNNSQFSKDLIERLHGQRFRVYKNDDMIGV-----LCGSVKNILAIATGISDGKLGSNARAALITRGLTEMGRLVSVFGGKTGLAGLGDLVLTCTDNQSRNRRVDKKEAQQAIGQAIEGLY-QVHALAQKHAIEMPLTFQVHRIL.......... 311
3 -19.300IDP01730 gene: gpsA; glycerol-3-phosphate dehydrogenase (NAD(P)+) [Francisella tularensis subsp. tularensis SCHU S4] FTT0871 [Francisella tularensis subsp. tularensis SCHU S4]  ali follow..  16  4.NILVLGAGAWGTALALQLAYRGHNVRINSWKAEHNEQMLKDNNNHLKAIQDWQANIIEFDSILVATPSSGFKNTILELKECILPQQNIISATKGFCHSEIAEDILPTTKF--------ALLTGPSFAKELANQLTAVVVASKDINYARYVQELFSNENFRCYTTTDIIGA-----VGGAVKNVLAITAGIAAGEFGVNAHAALITRGLAEIKKLGLKLGANIGLSCLGDLLLTCSDNQSRNRRMTIQQALKEVNNVVEGYF-AVYNLAKKHNVEMPLVFATYRIL.......... 310
4 -18.800IDP02668 gene: gpsA; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase [Bacillus anthracis str. `Ames Ancestor`] GBAA1526 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  15  3.KITVVGAGSWGTALAMVLADNGHDVRIWGNRSELMDEINTKHENSIVAYSSLEEALVDVNVVLIVVPTKAYREVLQDMKKYVAGPTTWIHASKGIEPGTKRISEVIEEEIPEDLIKDVVVLSGPSHAEEVGLRQTTVTSAAKRMEAAEEVQDLFMNSYFRVYTNPDIVGV-----LGGALKNIIALAAGITDGGLGDNAKAALMTRGLTEIARLGRKMGGNAGLTGMGDLIVTCTSVHSRNWRHSLEEVLESMGMVVEGVRTTAHELAEKMEVEMPITAALYDVL.......... 311
5 -15.900IDP06064 3-hydroxyacid dehydrogenase [Helicobacter pylori J99] NP_223303 [Helicobacter pylori J99]  ali follow..  15  1MKIGWIGLGAMGTPMATRLRDAGLEVSVYNRTESKAAPLKEKGVAV---YTSPIDLAAKVDLVFTMLDKAAIDAVLAPKFWEQMSKKIVVNMST----APLESLSLEKIAQKHQATYLEAPVSGSVGAAKAGALLILAA---GDEEVISKLKPVLAHLGSQTFYLGKVGQGTGAKLSINSLLAQMGV--------------------AYSEALLLAKRLGVDAESQIIGQSGMNSPLFQAKKGMWLQDNYPAAFSLKLMAKDIRLAKNEAGEAMKLPFLFQAEELYSQAEKS.... 266
6 -15.500IDP90690 gene: gpsA; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase [Campylobacter jejuni subsp. jejuni NCTC 11168] Cj1196c [Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819]  ali follow..  11  2MRIAVIGAGKWGSALHLALKE-NHNCFISSLHQRDLED------------FVSIKEALECEYLVFALSSQGMRAWLKENF--INKGQKILIASKGIEDDEIFLDFVPKENF--------CVLSGPSFAAEVMQKLPTALMISGINQELCKKFASFFPDFIKTYIDNDVRGA-----ICGAYKNVLAIASGISDGKLGNNARAALISRGLIEMHRFGKFFGTKLGLSGAGDLFLTATSVLSRNYRQKLDSILAELNEVAEGVK-AIEKLAKMKGIYTPIVNEVVAIFKGKS...... 285
7 -14.400IDP92023 glycerol-3-phosphate dehydrogenase, putative [Toxoplasma gondii ME49] TGME49_010260 [Toxoplasma gondii ME49]  ali follow..  13  17LKVSVVGSGNWGSVIAKIVALNAQEVRMWVYEEMLTDIINKTHENRLVALPDVVEACRDSDLLIFIMPHQFATKVCEQLAEVVPGHARAITLLKGLH-SDIFKTKLDIVDC--------CVLSGANVANDVAREEATIGYSPEETDAALIWQQLFDTPYFKVNALPDVAGV-----VCGAVKNVIAIAAGFCDGGLGTNAKTAIIRLGVEEMKQFAMIFFDNIMAETFFDVITTVFGGRNARCAQIEADLLKGQKLQGTLTTKEVYEVIAAYEVERPLFSVTYEIA.......... 348
8 -14.300IDP02492 gene: proC; pyrroline-5-carboxylate reductase [Francisella tularensis subsp. tularensis SCHU S4] FTT1559c [Francisella tularensis subsp. tularensis SCHU S4]  ali follow..  15  1MKICFIGGGNMAAAMIAGMTSHGQDIIVFDRNEHKCLNLIKK----INTSTSLLNTIKLADVLILAIKPQNMFELIKNIRDTVTSTQVIVTVAAGI-QTSAYEELFNKEISFARTI--------PNTPSSLGYGATGIFFNKVIAADKKDLVIDIMQTMGVVTVVED-----------EKEIDIVAAIASSGPAYYF----------FMEHMVEAAIKQGLDKKQAEKLVVAAQMALNTNENMSELRKNVTSKKGITYEAL-----NIFEQFNLGGIVDKAIQANIARAQQLAIE. 267
9 -14.100IDP92082 glycerol-3-phosphate dehydrogenase, putative [Toxoplasma gondii ME49] TGME49_107570 [Toxoplasma gondii ME49]  ali follow..  13  23LRVAVIGSGNWGSVIGKICAQNAEQVRMWVFEEKLTDIINQKHENVLVAVPDVVEACRGADLLVFVMPHQFVAKVCDQLAKVVPSHARAISLLKGLYVSDTIRSKLNIVEC--------AALSGANVANDVAREEATIGHSPDETDTALIWQQLFDKPYFKVNTLPDVAGV-----LCGAVKNVVALAAGFCDGGLGTNTKSAIIRLGVEEMKQFGMIFFDNVIAETFFDVITTVFGGRNARCAQIEAEMLNGQKLQGTLTAREVFEVISSHEVDHPLFTVTYDIA.......... 354
10 -12.900IDP02330 gene: ilvC-1; ketol-acid reductoisomerase [Bacillus anthracis str. `Ames Ancestor`] GBAA1419 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  11  18KKVAIIGYGSQGHAHAQNLRDNGFDVVVGLRKGKSWDKAKEDGFSVYTVA----EAAKQADVVMILLDELQPEVYEEEIAPNLQAGN-SLVFAHGFNVHFDQVKPPVNVDVFLVAPKGPGHLVRRTFSEGGAVPALFAVYQDATGVATEKALSYADGIGATRAGVLETTFKEETETDLFGEQAVLCGG----------------VTALVKAGFETLVDAGYQPE---------LAYFECLHELKLIVDLMYEGGLENMRYSVSDTAQWGDFVSGPRVVTEDTKKAMGTVLAEIQDG 284
11 -12.600IDP02524 gene: ilvC-2; ketol-acid reductoisomerase [Bacillus anthracis str. `Ames Ancestor`] GBAA1852 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  11  17KTVAVIGYGSQGHAQAQNLRDSGVEVVVGVRPGKSFEVAKADGFEVMSVS----EAVRTAQVVQMLLPDEQQAHVYKAEVEENLREGQMLLFSHGFNIHFGQINPPSYVDVAMVAPKSPGHLVRRVFQEGNGVPALVAVHQDATGTALHVALAYAKGVGIETTFQEETETDLFGEQAVLCGGVTKAGFETLTEGGYRPEIAYFECLHELKLIVDLMYEGGLTNMRHSISDTAE-VTDETKKEMKRVLTEIQQGKKWILENQAGRPTYNAMKKAEQNHQLEKVGEELREMMSWIHA. 328
12 -12.600IDP90757 gene: ilvC; ketol-acid reductoisomerase [Campylobacter jejuni subsp. jejuni NCTC 11168] Cj0632 [Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819]  ali follow..  13  19KKVAIIGFGSQGHAHAMNLRDNGVNVTIGLREGSVSAVKAKNA-----EVVSVSEASKIADVIMILAPDEIQADIFNVEIKPNLSEGKAIAFAHGFN---HYGQIVVPKGVDVIMIAPKAPGHTVRNEFTLGGGPCLIAIHQDESKNAKNLALSYASAIIETTFKAETETDLFGETLVEAGYEPEMAYFECTGPKIITEETKKAMKGVLKDIQNGVFAKDFILERRAGFARMHAERKNMNDSLIEKTGRNLRAMMPWIS--AKKLVDKDKN......................... 340
13 -11.900IDP06325 mannitol-1-phosphate 5-dehydrogenase [Streptococcus pneumoniae TIGR4] NP_344921 [Streptococcus pneumoniae TIGR4]  ali follow..  13  3.HSVHFGAGNIGGFIGEILFKNGFHIDFVDVNNQIIHALNEKGINSKEHPEQVIEAIQKTDIITTAIGPNILPFIAELLAKGITQALDVMACENMIGGSQFLYQ------EVKKYLSPEGLTFADNYIGFPNAAVDRIVPAQSHEDSLFVVVEPFNEWVVEVHYEEDLEPFIERKLFSVNSGHATSAYIGAHYGALQNPNIKSRIESVLAEIRSLLIAK-WNFDKKELENYHKVIIERLEN-----------------PFIVDEVSRVARTPIRKLGYNERFIRPIRELKEL.... 318
14 -11.600IDP90565 ketol-acid reductoisomerase [Vibrio cholerae O1 biovar eltor str. N16961] VC0162 [Vibrio cholerae O1 biovar El Tor str. N16961]  ali follow..  15  38KKVVIVGCGAQGLNQGLNMRDSGLDVSYALRQRQSFKNAKNNGFNVGSYE----QLIPTADLVINLTPDKQHTSVVNAVMPLMKQGA-ALGYSHGFNIVEEGMQIRKDITVVMVAPKCPGTEVREEYKRGFGVPTLIVHPENDPQGEGWEIAKAWAAA-LASSFVAEVKSDLMGEQTILCGM--LQAGSIVADG-IDPGYAGKLLQFGWETITEALKFGGITHMMDRLSNPAKELKDLMRPLYNKHMDDIISGHFSS....................................... 314
15 -11.500IDP02179 gene: proC; pyrroline-5-carboxylate reductase [Coxiella burnetii RSA 493] CBU_2090 [Coxiella burnetii RSA 493]  ali follow..  14  4SNITFIGGGNMARNIVVGLIANGNRICVTNRSLDKLDFFKEK----VHTTQDNRQGALNADVVVLAVKPHQIKMVCEELKDILSETILVISLAVGV-TTPLIEKWLGKASRIVRAM--------PNTPSSVRAGATGLFANETVDKDQKNLAESIMRAVGLVIWVSS-----------EDQIEKIAALSGSGPAYIF----------IMEALQEAAEQLGLTKETAELLTEAARMALETEQSVVQLRQFVTSPGGTTEQAI-----KVLESGNLRELFIKALTAAVNRAKELSKT. 271
16 -11.400IDP04467 putative nucleotide sugar dehydrogenase [Yersinia pestis CO92] YPO2174 [Yersinia pestis CO92]  ali follow..  12  1MKVTVFGIGYVGLVQATVLAEVGHDVLCIDIDANKVADLKKGRIAILQFSTDAQAGVAHGVIQFIAVGT-YVLDVASTIGTYMDSPKVIIDKST-VGTADKVHQVIQAILEQRGEKIDFSVVSNPEFLKEGAAERIVIGIDTDDSGALELISELYEPRNHDRMLVMDIRSAELTKYAANGMLATKISFMN---------EIANIAERLGADIEKVRQGIGSD-DKGYKPQLLQAVEQINNQQKYKLTEFIKSHFNSQLAGKTFAVWGLAFKPNTDDMREAPSRVVMESLWEAGAT. 353
17 -11.300IDP01235 gene: wecC; UDP-N-acetyl-D-mannosamine dehydrogenase BA_5512 [Bacillus anthracis str. Ames]  ali follow..  14  1MKICTMGLGYIGLPTSAMFAKYGTEVVGVDIHQKVVDKLNNGEIHIEEPGLGESLTPEEADAFIISVPT-YVLTATEKVLPFVKKGNVIIVEST-PRSMDDYVKPLVEEAGFTV-LVHCPERVLPGQILHEHNNRIVGGVTPACAEAGARVYGVFVEGEIIKT---NAKTAEMSKLMENALANELTKVCNSLDGHCLAVDPYFIVAKAPELANIIKLSRETNVSMPHVTEKVKELLAGVENPKVAAFGNVDDMRESPAMDVIDLIRNEGITVSAHDPHVESDFFELHSAEEAVKDA 364
18 -10.800IDP00702 gene: cap5O; capsular polysaccharide biosynthesis protein Cap5O SACOL0150 [Staphylococcus aureus subsp. aureus COL]  ali follow..  13  1MKLTVVGLGYIGLPTSIMFAKHGVDVLGVDINQQTIDKLQSGQISIEEPGLQESTTPDASDVFIIAVPT-LVMRALDSILSFLEKGNTIIVEST-PKTMDDFVKPVIENLGFTI-LVHCPERVLPGKILEEHNNRIIGGVTEACIEAGKRVYRTFVQGEMIET---DARTAEMSKLMENTYRDVNIALAN---------ELTKICNNLNINVLDVIEMANKH-ENAKLIQTGREINNSMPAYVVDTTKQIIKVLSGNKVTVFGLTYKGDVDDIRESPAFDIYELLNQ......... 335
19 -10.600IDP01494 UDP-glucose 6-dehydrogenase VCA0780 [Vibrio cholerae O1 biovar El Tor str. N16961]  ali follow..  15  1MKIAIAGTGYVGLSNGILLAQ-HNEVVALDIVVSRVEQLNQHQPLNFRATCDKRDAYQDAQFVVIATPTRTVEAVIDDVLAINPQAIMVIKSTVPVGYTKRIKQRLCCNNLIFS------LREGRALYDNLYPSRIIVGEKSERGQAATLLAQGAKKMDIPILLT-HSTEAEAVKLFSNT-FNELDTYAETHGGYCLPKDTRQLLRNFEDVPNNLIRAI-VDANTTRKDHIAFSILNRNPKVVGIMKSGSDNFRASSILGIMKRIKAQGVEVVIYEPV.................. 338
20 -10.500IDP00140 pyrroline-5-carboxylate reductase, putative BA_0197 [Bacillus anthracis str. Ames]  ali follow..  11  5HRILFIGAGRMAEAIFSGLLKTSKEEIIVSNRSNVEKLDQLRARYNVSTTTDWKQHVTSVDTIVLAMPPSAHEELLAELSPLL-SNQLVVTVAAGI-SPSYLEERLPGGTPVAWIM--------PNTAAEIGKSISLYTMGQFNETHQETLQLLLRGIGTSQLCTEEE-------------VHQLTAVTGS-----------AFLYYFAESLIEATKSYGVD------EATAKHLVIQMISGSASMLEQ............................................... 219
21 -10.500IDP01406 gene: wecC; UDP-N-acetyl-D-mannosamine dehydrogenase VC0918 [Vibrio cholerae O1 biovar El Tor str. N16961]  ali follow..  15  4.KVSVIGLGYIGLPTAAVLASRGLDVVGVDVNAHAVDTINKGEIHIVEPDLDITLTAEPADAFLVAVPT-YIEAAAKTIAPVLAKGNLVVLEST-VGTTEKLAQWLAEAR--PDLTFPQQKGIAADVKIAYCPERVLPGYVLQELVSNDRVIGGVSKA------CSEKAVALYKTFVKGECI--VTNARTAEMAKLTENSFRDVNIAFANELSLVCNKLKINVDEAQLIRTAREVNDGKPHWVVDQVKQAADQFKKPIIACLGLAFKADIDDLRESPALDITKHLAE......... 343
22 -10.400IDP01969 gene: kfiD; putative UDP-glucose 6-dehydrogenase [Campylobacter jejuni subsp. jejuni NCTC 11168] Cj1441c [Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819]  ali follow..  13  1MKIVIVGIGYVGLANAILFSKNNNEVVLLDIDENKIQSINVQNISKLHATSNIKEAYFNADFAVIATPTRSIENVLKDIKNINSKINVIIKSTVPIGYTKTIKQKFNMSNIVFS------LREGSALYDSLYPSRIIIGDKSVLGKTIGDLFLKNIEKKNVDIFYMDSDEAESVKLFSNT-FNEVDSYA-----RKHNLNSADIIKGISADIGKYYNNPSFGYGGYCLPKDTKQLLANFYNIPNSLIKAIVETNEIRKKFITQLILEKKPN......................... 299
23 -10.400IDP00425 gene: wecC; UDP-N-acetyl-D-mannosamine dehydrogenase YPO3863 [Yersinia pestis CO92]  ali follow..  15  4ETISVIGLGYIGLPTAAAFASRKKKVIGVDVNAHAVETINRGAIHIVEPDLDKVTKPQAADAFLIAVPT-FVESAAKSIAPVLKKGDLVILEST-VGATEQMAQWLAEAR--PDLSFPQQAGEAADINIAYCPERVLPGQVMVELIQNDRVIGGMTPK------CSARASALYKIFLEGECV--VTNSRTAEMCKLTENSFRDVNIAFANELSLICDEQGINV......................................................................... 240
24 -9.960IDP02226 gene: yqjI; 6-phosphogluconate dehydrogenase [Bacillus anthracis str. `Ames Ancestor`] GBAA0164 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  12  4LQIGVVGVGVMGKSLALNFESKGYSVALYDISKEKVDETIEENRGKNLVGTHIVEEFVNS-ILLMVNAGEITDKAIDSLVPHLDKGDILI----------------------GGNTYFVDTIRRNKRLAEEGINFIGAGVSGGEEGALKGPSIMPGGQKDAYEKVKDMLENISAKVNNEPCCSYIGPNGAGHYVKMVHNGIEYGDMQLICEAYFFLKQTLDLTAEE-----FHEIFAENKGELNSYLIEITADIFKKKDEETGKPLGTGKWTSQSALDLGISLPIITE........ 282
25 -9.230IDP91227 gene: tyrA; T-protein [Escherichia coli CFT073] NT04EC3201 [Escherichia coli CFT073]  ali follow..  16  101.VVIVGGGGQMGRLFEKMLTLSGYQVRILEQHDWD----------------RAADIVSDAGMVIVSVPIHVTEQVIGKLPP-LPKDCILVDLASVKNGPLQAMLAAHDGPVLGLHPMFGPDSGS--------AKQVVVWCDGRKPEAYQWFLEQIQVWGARLH---RISAVEHDQNM--AFIQALRHFATFAYGLHLAEENVQL-----EQLLALSSP----------YRLELAMVGRLFAQDPQLYADIIMSSERNLALIKRYYKRFGEAIELEQGDKQAFIDSFRKVEHWFGD. 352
26 -9.160IDP06299 6-phosphogluconate dehydrogenase [Streptococcus pneumoniae TIGR4] NP_344902 [Streptococcus pneumoniae TIGR4]  ali follow..  16  4ANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIACHPEKNFVPSYDVESFVNS-IMLMVQAGPGTDATIQALLPHLDKGDILIDGGNFYKDTIRRNEELANSGIIGTGVSGGEKGALEGPSIMPG----------GQKEAYELVADVLEEISAKAPEDGK---------------PCVTYIGPDGAGKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAEIFTEWNKGELDSYLIEITADILSRKDDEVDYILDAAGNKGTGKWTSQSSLDLGVPLSLITESVFAR. 290
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Godzik A. cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences. Bioinformatics. 2006 May 26;