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Query: IDP05722 gene: tyrA; prephenate dehydrogenase [Bacillus anthracis str. Ames] BA_2954 [Bacillus anthracis str. Ames], from CSGID

Results of FFAS03 search in CSGID
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MKIKKESLEMRQMRKKVVLIGTGLIGGSLALAIKKDHDVTITGYDIFQEQVERAKELHVVDEIAVDLQHACEEAHLIVFASPVEETKKLLHKLASFHLREDVIVTDVGSTKGSIMNEAEALFSKEISFIGGHPMAGSHKTGVESAKAHLFENAFYILTPMHHVPNEHVEELKDWLKGTGSHFLVLNTEEHDYVTGIVSHFPHLIAAGLVKQVEKHAGDNPLIHQLAAGGFKDITRIASSSPKMWSDIVKQNREHLMVLLKEWISEMEDLYDTVSSGDAGEIQNYFADAKEYRDSLPVRKRGAIPAYHDLYVDVLDKVGALAHVTSILAREEISITNLQILEAREGLLGVLRISFQREEDRMKAKLALGEEKYQTYETILast
1 -101.000IDP05722 gene: tyrA; prephenate dehydrogenase [Bacillus anthracis str. Ames] BA_2954 [Bacillus anthracis str. Ames]  ali  100  1MKIKKESLEMRQMRKKVVLIGTGLIGGSLALAIKKDHDVTITGYDIFQEQVERAKELHVVDEIAVDLQHACEEAHLIVFASPVEETKKLLHKLASFHLREDVIVTDVGSTKGSIMNEAEALFSKEISFIGGHPMAGSHKTGVESAKAHLFENAFYILTPMHHVPNEHVEELKDWLKGTGSHFLVLNTEEHDYVTGIVSHFPHLIAAGLVKQVEKHAGDNPLIHQLAAGGFKDITRIASSSPKMWSDIVKQNREHLMVLLKEWISEMEDLYDTVSSGDAGEIQNYFADAKEYRDSLPVRKRGAIPAYHDLYVDVLDKVGALAHVTSILAREEISITNLQILEAREGLLGVLRISFQREEDRMKAKLALGEEKYQTYETI 378
2 -43.900IDP91227 gene: tyrA; T-protein [Escherichia coli CFT073] NT04EC3201 [Escherichia coli CFT073]  ali follow..  14  92......KTLCPSLRPVVIVGGGGQMGRLFEKMLTLSG-YQVRILEQHDWD---------------RAADIVSDAGMVIVSVPIHVTEQVIGKLPP--LPKDCILVDLASVKNGPLQAMLA--AHDGPVLGLHPMFGPDSGS--------LAKQVVVWCDG--RKPEAYQWFLEQIQVWGARLHRISAVEHDQNMAFIQALRHFATFAYGLHLAEENVQLEQLLALSSPIYRMVGRLFAQDPQLYADIIMSSERN-LALIKRYYKRFGEAIELLEQGDKQAFIDSFRKVEHWFGDYAQRFQSESRVLLRQANDNRQ............................................................... 373
3 -43.300IDP00461 gene: tyrA; bifunctional chorismate mutase/prephenate dehydrogenase YPO3285 [Yersinia pestis CO92]  ali follow..  15  92......KTLCPELRPVVIIGGQGQMGRLFSRMLNLSG-YQVRTLEQEDWS---------------QAESILADAGMVIVSVPIHITEEVINRLP--KLPADCILLDLASVKNKPLQAMLA--AHEGPVLGLHPMFGPDVGS--------LAKQVVVYCDG--RDPQAYQWLLEQLQVWGARLHRISAVEHDQNMAFIQALRHFATFAYGLHLAEENVQLEQLLALSSPIYRMVGRLFAQDPQLYADIIMSSEDNL-ALIKRYYKRFGEALTLLEHHDKQAFVQSFEKVEHWFGDYAER---FLVESRSLLRQANDN.............................................................. 371
4 -14.600IDP06064 3-hydroxyacid dehydrogenase [Helicobacter pylori J99] NP_223303 [Helicobacter pylori J99]  ali follow..  10  2...............KIGWIGLGAMGTPMATRLRDAG-LEVSVYNRTESKAAPLKEKGV--AVYTSPIDLAAKVDLVFTMLSDKAAIDAVLAPKFWEQMSKKIVVNMSTIAPLESLSLEKIAQKHQATYLEAPVSGSVGAAKAGALLILAAG-----------DEEVISKLKPVLAHLGSQTFYLGKVGQGTGAKLSINSAESFLQIIGQSGMNSPLFQAKKGMWLQDNYPAAFSLKLMAKDIRLAKNEAGEAMKLPFLFQAEELYSQAEKSLGGLDMAAVYHYLEKGEH........................................................................................ 285
5 -13.800IDP90757 gene: ilvC; ketol-acid reductoisomerase [Campylobacter jejuni subsp. jejuni NCTC 11168] Cj0632 [Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819]  ali follow..  13  19..............KKVAIIGFGSQGHAHAMNLRDNGVNVTIGLREGSVSAVKAKNAGFE---VVSVSEASKIADVIMILAPDEIQADIFNVEIKPNLSEGKAIAFAHGFNIHYGQIVVPKGVDVIMIAPKAPGHTVRNEFTLG------GGTPCLIAIHQDESKNAKNLALSYASAIGG--AETETDLFGEQAVLCGGLSALIQAGFETLVEAGYEPEMAYFECLHGGIADMRYSISNTAEYTKKAMIQNGVFAKDFILERRAGFARMHAERKNMNDSLIEKTGRNLRAMMPWISAKK............................................................................... 333
6 -13.200IDP02492 gene: proC; pyrroline-5-carboxylate reductase [Francisella tularensis subsp. tularensis SCHU S4] FTT1559c [Francisella tularensis subsp. tularensis SCHU S4]  ali follow..  16  2...............KICFIGGGNMAAAMIAGMTSHGYKDIIVFDRNEHKCLNLIKKYNI-NTSTSLLNTIKLADVLILAIKPQNMFELIKNIRDTVTSTQVIVTVAAGIQ---TSAYEELFNKEISFARTIP-----------NTPSSLGYGATGIFFNKVIAADKKDLVIDIMQTMGVVTVVEDEKEIDIVAAIASSGPFQFMEHMVEAAIKQGLDKKQAEKLVVQGAAQMALNTNENMSELRKNVTSKKGITYEALNIFEQ--FNLGGIVD----KAIQANIARAQQLAIEFTKL................................................................................ 271
7 -12.900IDP00140 pyrroline-5-carboxylate reductase, putative BA_0197 [Bacillus anthracis str. Ames]  ali follow..  16  5..............HRILFIGAGRMAEAIFSGLLKTSKEEIIVSNRSNVEKLDQLRARYNVSTTTDWKQHVTSVDTIVLAMPPSAHEELLAELSPL-LSNQLVVTVAAGIS---PSYLEERLPGGTPVAWIMP-----------NTAAEIGKSISLYTMGQFVNETHQETLQLLLRGIG-TSQLCTEEEVHQLTAVTGSAPYYFAESLIEATKSYGVDEATAKHLVIQMISGSASMLEQDPANLREQVTTPGGSTAEGLKAL.................................................................................................................... 244
8 -12.900IDP02524 gene: ilvC-2; ketol-acid reductoisomerase [Bacillus anthracis str. `Ames Ancestor`] GBAA1852 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  12  17..............KTVAVIGYGSQGHAQAQNLRDSG-VEVVVGVRPGKSFEVAKADGF----VMSVSEAVRTAQVVQMLLPDEQQAHVYKAEVEENLREGQMLLFSHGFNIHFGQINPPSYVDVAMVAPKSPGHLVRRVFQEGN------GVPALVAVHQDATGTALHVALAYAKGVGCTRAGVIETTFQEETETDLFGEQAVLCGGVTALVKAGELKLIVDLMYEGGLTNMRHSISDTAEVLTEI--QQGEFAKKWILENQAGRPTYNAMKKAEQNHQLEKVGEELREMMSWIHAPK............................................................................... 330
9 -12.700IDP02179 gene: proC; pyrroline-5-carboxylate reductase [Coxiella burnetii RSA 493] CBU_2090 [Coxiella burnetii RSA 493]  ali follow..  13  4..............SNITFIGGGNMARNIVVGLIANGYDRICVTNRSLDKLDFFKEKCGV-HTTQDNRQGALNADVVVLAVKPHQIKMVCEELKDILSETKILVISLAV--GVTTPLIEKWLGKASRIVRAMP-----------NTPSSVRAGATGLFANETVDKDQKNLAESIMRAVGLVIWVSSEDQIEKIAALSGSGPFLIMEALQEAAEQLGLTKETAELLTEQGAARMALETEQSVVQLRQFVTSPGGTTEQAIKVLES--GNLRELFI----KALTAAVNRAKELSKTVDQ................................................................................. 274
10 -12.000IDP02330 gene: ilvC-1; ketol-acid reductoisomerase [Bacillus anthracis str. `Ames Ancestor`] GBAA1419 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  12  18..............KKVAIIGYGSQGHAHAQNLRDNG-FDVVVGLRKGKSWDKAKEDGF---SVYTVAEAAKQADVVMILLPDELQPEVYEEEIAPNLQAGNSLVFAHGFN---VHFDQVKPPVNVDVFLVAP----KGPGHLVRRTFS-GAVPALFAVYQDATGVATEKALSYADGIGATRAGVLETTFKEETETDLFGEQAVLCGGVTALVKAG---------------ETLVDAGYQPELAYFECLHELKLIVDLM....................................................................................................................... 238
11 -10.300IDP02226 gene: yqjI; 6-phosphogluconate dehydrogenase [Bacillus anthracis str. `Ames Ancestor`] GBAA0164 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  16  5...............QIGVVGVGVMGKSLALNFESKG-YSVALYDISKEKVDETIEENRGKNLTHIVEEFVNSLESILLMVNAGEITDKAIDSLVPHLDKGDILIDGGNTYVDTIRRNKRLAEEGINFIGA-GVSGGEE-GALKGPSIMPGG-----------QKDAYEKVKDMLENISAKVNNEPCCSY----NGAGHYVKMVHNGIEYGDMQLICEAYFFLKQTL....................................................................................................................................................... 207
12 -10.200IDP90565 ketol-acid reductoisomerase [Vibrio cholerae O1 biovar eltor str. N16961] VC0162 [Vibrio cholerae O1 biovar El Tor str. N16961]  ali follow..  13  38..............KKVVIVGCGAQGLNQGLNMRDSGLDVSYALRQAAIDEQRQSFKNAKNNGFNSYEQLIPTADLVINLTPDKQHTSVVNAVMPLMKQGAALGYSHGFN----IVEEGMQIRKDITVVMVAPKCPGTEVREEYKRGF---PTLIAVHPENDPQGEGWEIAKAWAAATGGHRSSFVAEVKSDLMGEQTILCGMLQAGSYEKMVADGIDPGYAGKLLQFGWETITEALKFG-PLYNKHMIISGHFSSTMMADWANDDKDLFGWRAETAETAFENYPTTDVKIAEQEYFDNGAMVRAGVELAFEAMTASGELPLIANTVARKRLYEMNVVISDTAEYGNYLFANVAVPLLREKFMPKVGTD......... 443
13 -10.100IDP01969 gene: kfiD; putative UDP-glucose 6-dehydrogenase [Campylobacter jejuni subsp. jejuni NCTC 11168] Cj1441c [Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819]  ali follow..  11  2...............KIVIVGIGYVGLANAILFSKNNENEVVLLDIDENKIQSINNHKS--HATSNIKEAYFNADFAVIATPTRSIENVLKDIK--NINSKINVIIKSTVPIGYTKTIKQKFNM----IVFSP----EFLREGSALYDSLYPSRIIIGDKSVLGKTIGDLFLKNIEKKNVDIFYMDSDEAE-SVKLFSNTYLAMRVGFFNEVDSYARKHNLNSADIIKGISADDRIGKYSFGYGGYCLPKDTKQLLANFYNIPNSLIKAIVETNEIRKKFITQLILEKKPNILGIYR---------LIMKQNSDNRNSVIIDIIKYLQEYNSNIE........................................... 335
14 -10.000IDP06299 6-phosphogluconate dehydrogenase [Streptococcus pneumoniae TIGR4] NP_344902 [Streptococcus pneumoniae TIGR4]  ali follow..  19  5...............NFGVVGMAVMGRNLALNIESRG-YTVAIYNRSKEKTEDVIACHPEKNFSYDVESFVNSIEKIMLMVQAGPGTDATIQALLPHLDKGDILIDGGNTFKDTIRRNEELANSGINFIGT-GVSGGEK-GALEGPSIMPGG-----------QKEAYELVADVLEEISAKAPEDGKP-------CVTYIGPDGAGHYVKMVHNG---EYGDMQLIAESYDLMQHLLGLSAEDMAEIFTENKGELDSYLIEITADI................................................................................................................ 239
15 -9.250IDP00951 gene: ycdW; putative oxidoreductase STM1135 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  10  137..............FSVGIMGAGVLGAKVAESLQAWG-FPLRCWSRSRKSWPGVESY----VGREELRAFLNQTRVLINLLPTAQTVGIINSELLDQLPDGAYVLNLARQEADLLAALDSLKGAMLDVFSQEPLP---------QESPLWRHPRVAMTPHIAAVTRPAEAIDYISRTI........................................................................................................................................................................................................ 293
16 -9.160IDP01406 gene: wecC; UDP-N-acetyl-D-mannosamine dehydrogenase VC0918 [Vibrio cholerae O1 biovar El Tor str. N16961]  ali follow..  12  1............MFNKVSVIGLGYIGLPTAAVLASRG-LDVVGVDVNAHAVDTINKRSAVMTGKLKATLTAEPADAFLVAVPLSYIEAAAKTIAPVLAKGNLVVLEVGTTEKLAQWLAEARPDLTFPKIAYCP----ERVLPGYVLQELVSNDRVI----GGVSKACSEKAVALYKTFVKGECIVTNARTAEMAKLTENSFRDVNIAFANELSLVCNK-NVWELIRLANRHPRVSILNPGPGVGGHCIAVDPWFIVNSCPDEAQLIRTAREVNDGKPHWVVDQVKQAADQFKKPIIACLGLAFKADID---DLRESPALITKHLAESKVGQLLAVEPNITELPSKLAKQGIELVSLERALELANIVVVLVDHKEFKAA 395
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Godzik A. cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences. Bioinformatics. 2006 May 26;