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Query: IDP90389 hypothetical protein [Chlamydia trachomatis D/UW-3/CX] CT_384 [Chlamydia trachomatis D/UW-3/CX], from CSGID

Results of FFAS03 search in CSGID
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MCCVDGSNSIQQRMRFCEYRTAAQEAKTSLSSDCSLLEARLALRALAKHHEYSAWREAFLRSQERFPSLEADRDIHEDLAASLLQKNIRHSSLTVRVITILAVGMARDYRLVPIVLQALSDDSDTVREIAVQVAVMYGSSCLLRAVGDLAKNDSSIQVRITAYRAAAVLEIQDLVPHLRVVVQNTQLDGTERREAWRSLCVLTRPHSGVLTGIDQALMTCEMLKEYPEKCTEEQIRTLLAADHPEVQVATLQIILRGGRVFRSSSIMESVQKLACNSLSARVQMQAAAILYLEGDPFGEDKLTEGLSATSSILCEAASEAVCSLGIHGVHLAGRFLSKVQGMRSRVNLAFALLVSREKVEEAGDVVASFIHRIEPCRAIEQFLCEDQKIFVASSPLQVEIMKRDLAKKIIRLLVAAQYSKAKMVVAQYLAGQQVGWSFCSEVFWEEGDSEDFVEPLQEESFAFALEKALSFLQREGGEAGLHAVISLYPHSRWQDKLTILEAIAYSENRIATCFLRERCLQEAASLQSAAAGAVFALFKLast
1 -125.000IDP90389 hypothetical protein [Chlamydia trachomatis D/UW-3/CX] CT_384 [Chlamydia trachomatis D/UW-3/CX]  ali  100  1MCCVDGSNSIQQRMRFCEYRTAAQEAKTSLSSDCSLLEARLALRALAKHHEYSAWREAFLRSQERFPSLEADRDIHEDLAASLLQKNIRHSSLTVRVITILAVGMARDYRLVPIVLQALSDDSDTVREIAVQVAVMYGSSCLLRAVGDLAKNDSSIQVRITAYRAAAVLEIQDLVPHLRVVVQNTQLDGTERREAWRSLCVLTRPHSGVLTGIDQALMTCEMLKEYPEKCTEEQIRTLLAADHPEVQVATLQIILRGGRVFRSSSIMESVQKLACNSLSARVQMQAAAILYLEGDPFGEDKLTEGLSATSSILCEAASEAVCSLGIHGVHLAGRFLSKVQGMRSRVNLAFALLVSREKVEEAGDVVASFIHRIEPCRAIEQFLCEDQKIFVASSPLQVEIMKRDLAKKIIRLLVAAQYSKAKMVVAQYLAGQQVGWSFCSEVFWEEGDSEDFVEPLQEESFAFALEKALSFLQREGGEAGLHAVISLYPHSRWQDKLTILEAIAYSENRIATCFLRERCLQEAASLQSAAAGAVFALFK 539
2 -66.900IDP90382 hypothetical protein [Chlamydia trachomatis D/UW-3/CX] CT_350 [Chlamydia trachomatis D/UW-3/CX]  ali follow..  12  4...................SRLAFISFLSFTLSASCDFPSSVSQRILFSCR-KSVPQALEAYLEASATYQHDFSVLRVIAESYLQQSFLSEDTYIRKSAIIGAGLSGSSEALELLSEAIETQDLYEQLLILNAATSQLSKTSDKLLFKGL-TASHPVIRLEAAYRLACMKNSKVSDYLYSFIYKLPE--EIQNLAATIFLQLETEEADAYPNNLTRNYVAYLIGEYKQKRFLPTLRSLLTSASPLDQEGALYALGKLEDSGSYPRIKA-----LSSRSNPEVVLAAAQTLLFLEKEEEALPILTNLCQQKLLRALYTARFLSQEK--GEELLLPIFYNATQEEIRLNTALALVHQGCTDPQVLHYLTEILESKVLHRIFLPTHSTGKAIQFWKECTTFPLMSQEAEDTILSALLKLPNDAYLPYLERILASQKTILAAKAIAFLSVTAHPQALSLVTPGDPIIRAYANLALENPLPSPSSSYLRYQVSPETRTQLMLAILETLVSSKTDEDIRVFLSLMKKTHYKNIPILSGLLMRIVE 566
3 -19.200IDP91695 gene: KPNA1; importin subunit alpha-1 [Homo sapiens] NP_002255 [Homo sapiens]  ali follow..  8  80...........................................................................................................GGVITSDMIEMIFSKSPEQQLSATQKFRKL-TPGVVARFVEFLKRKENCTLQFESAWVLTNIASGNS----------------------------------------------LQTRIVIQAGAVPIFIELLSSEFEDVQEQAVWALGNIAGDSTDCNILPPLLQLFSKQNRLTMTRNAVWALSNL-VSPCLNVLSWLLFVSDTDVLADACWALSYLSDGPNDKIQAVIDAG------CRRLVELLMHNDYVSPALRAVGNIVTGDDIQT---------------------QVILNCSALQSLLHLLSSPKESIKKEACWTISNITAGNRAQIQTVIDANIFPALISILQTAEFRTRKEAAWAITNATSELGCIKPLCDLLTVMDSKIVQVALNGLENI-EAYGLDKIEFLQSHENQEIYQKAFDLIEHYFG 505
4 -17.800IDP06032 beta-adaptin-like protein, putative [Toxoplasma gondii ME49] EEB01577 [Toxoplasma gondii ME49]  ali follow..  9  9...................PPPPPPTHHVVVPRPPAGPQFFVDQKRGELYELRQVLRSLPTERDVTKQRDALKKLIAYMTVGLVVMLASTADLVQKKMIYQYLTNYADTNAINTFQKDCNDEDPRLRGLALRSLCSLRLSCMLEYIEPAARKDPSPYVRRAAVMGMLKV-IDEIRQRLHEALFDDDPQVT--INAICALNELEAETGGLQV----------------TKKIATHFLNRIKRFSEWGVCVILNLVASYQPETEEEADVMNILDDKLKSSSAAVVLGCANCFLELTRCRLKPPLLTLATTGYPEIAHTILRHILLIVQTGGEDAVEIFAYTDPSYLKA--------------TKLQTLAAIATENNCVDMIAEIRE------------YVCDADADIARQSLAALGVIAC-RIPSAADDVV--------------------TLLLSFVEMELADFLASAAFVILRDI-ISRLVEAIRIYALRSDGEGVAAVVWMLGEFSKNYILEEIVDRFDEEPPVVRMELLTAATKTF. 528
5 -17.700IDP92583 beta adaptin protein, putative [Toxoplasma gondii ME49] TGME49_040870 [Toxoplasma gondii ME49]  ali follow..  9  3..........DGNYFQPAKRGELHELKEELHSSNKEKKKEAVKKVIAAMTVGKDVSSLFPD----------------------VVNCMQTTNMELKKLVYLYVINYAKAQAINTFRKDSLDPNPLIRALAVRTMGCIRLEEITEYLVEPLRRDPDPYVRKTAAICVAKLGEEGFIEELTTMLSDSNPVV---ANAVAALSEISENSGRNYMKNILNAK----------ESNVNKLLAALNECTEWGQVFILDALAQFEETPRAAESVLDRVTARLSHANSAVVLSAIKVVMKLLDHRKLCPPLVTLLSAEPEIQYVALRNIELIVQKRPSILASEVKYNDPVYVK--------------IEKLDILVRLVSEKNVDQVLSELKE------------YATEVDVDFVRKAVRCIGRCAIKLDCAA-------------------------AVLLDLIQTKVNYVVQEAIVAIKDIFRKESMISTLCENLETDEPAAKASMVWIVGEYVDRELLETFLETFHDEPSIVQLQLLTATVKL.. 493
6 -17.100IDP06029 adaptin N terminal region domain-containing protein [Toxoplasma gondii ME49] EEB01203 [Toxoplasma gondii ME49]  ali follow..  13  58..KVTAMKRLLAAHAGGADVSALLPEVVKAIAVPDLELKRLVYLFLIQYAEGNRDLAL--------------------LSINSFQKDLTDRNQVVRAAALKALASIRLLEVVQLLVRAAADCSPFVRRTAAQCVVKV-DQDQFEELKSIVLTDVEVSVVGAALIAFREL--LHEGESHPDDREQYLECTYTPTGENGGLRTATPRTPLPVPGLEAADQGKDAREFRGQAAALARLQKCLLQLEPFTQVVAVDIFMRYCRLPTDFRLFLSNLPLLLHSESSAVVVAATAALFSLLPQAAVHPLLRCMHTSAPDLQEPLLHTIAVLGSAAPSLFIPHVRSSDSPTVKQAK--------------LKVLRSLLVSASSQYSSGDGVSSLALLLLTEVRTYIHWGDQALLSSSFRLLTFLAQAASMQTFVQLLDAPSAALAAEAVLA--------LQTLLQRQLEQQRE----SSARGGQLGHLLLQLVSQFPRHAPPARASVVWIVGQYQREDFLRQLVPKFKAEAEEVKLQILLLALKV.. 673
7 -16.500IDP04465 hypothetical protein [Yersinia pestis CO92] YPO1994 [Yersinia pestis CO92]  ali follow..  9  150............................................................................EVVELNCYGDKILSPNTVMFYFRSKDVHTQYPPDELSVSLNLIVRPIKSKHQYEFQIDSDALEGKIEARIKKG--RYERYAFQNVLYNGLLSLENEKSRQLVHKVS--------------------------------------------------------LCNHREEIRLIAYEALLKHAQKKGNVSDIKSISEQAFKDQSLYIKNKISHSIGSMPCMSPKPR.............................................................................................................................................................................................................................................. 316
8 -14.100IDP92584 adaptin N terminal region domain-containing protein [Toxoplasma gondii ME49] TGME49_044290 [Toxoplasma gondii ME49]  ali follow..  9  58......IRSLYVELLGHDASFAHFHAVKMTNQTNNIKAKRLGYLACNLF-------------------LSEDNELM--LLINTIQKDLASPNILNVQSALHCVARLLTPEMLPALLSLLQHSHAAVRRKAVMAVHKV--EGLREKMRRAL-CDSDPSVMAVSLHVIHRLAAKNLVSSLVSILKQIIDRKLPKDYEYHRVPA-------------IQIKILSLLSTLASEEVYELLQEVMRRADAAVIYECVRTIAALYPYPKLLDIAGCSISRFISAENNNLRYVGVTGLAAV--TQHQLVVVDCLEDSDDTLKRKTLDLLVKITNPVVEKLLGHSRATVDAHLRANLIQKIIMLAERYSPDPRWFLETI------------------------------------LCVLEVSGPSLPLASGGNAGARRCLSGGSTAGNLAAGLCYSTAYSLLQLVAEGPTDDEESDKAF------REYAVNDMVALLERKKLVIPDVLMQVLGEFGCESVIDLLASCLERSDPTTQAWILTAILKL.. 591
9 -14.100IDP92606 gamma-adaptin, putative [Toxoplasma gondii ME49] TGME49_113670 [Toxoplasma gondii ME49]  ali follow..  12  7....EFIRNIRAAKTAADERAVVSKECAEIRTAFKEGDGRYRHRNVAKVPTQFAQLECLKLLASPRFAEKRVGYLVLMLATNSIKNDLQHPNQYVNGLALTALGNIGTGEMCGAIMDLLRCSNPFIRKKAALCGVRV--EKLLACLPALL-ADRNHGVLISACALITALAERDMRTHIPTLVKSLKACLTAGYAHAAEYDIAGITDP-------LQCRLLRVLALLASASLSDVLAHVATNTEGAKNVGCVRTIMTIEDDPGLRVLGVNILGRFLSSRELNVKYVALGTLQQV--MRHRDILLDCLKDQDLSLRRRAVEVLFCLITDDVKELLNFLLMLNDAEFKQFVVNKIAVAASRHAPSTRWQIDTL--------------------LKLMTLGGDAVDDAITYSFVDLVVSTPPSYVVHKCYFSFQHSLSNNAALWQAGV--GEFGDLLVSMTEDTLAITPRQVADLL-----ISVADQLSSFPKAKQGVLTQTLLTAAAKL-RERLVGLLKRFETSNNVEVQQRSSE-YMGLLE 589
10 -13.500IDP92581 splicing factor 3a protein, putative [Toxoplasma gondii ME49] TGME49_021940 [Toxoplasma gondii ME49]  ali follow..  9  5............................................................................................................IRGVSLFIQDVRREQARVLQELSKIRQRFAHPKK--PLTGYEKKK----TKLLYIHLLGYPVDIGHAEAIS--LLSSPHYSERSAAFLFCSLLLVDSHTASRDLPDLRSLCCSSIKK-------------LSLQHEDFAALALDCASYISDPDAAAELFPLMQATASSSASPLIRQKAYSCMLVF----ASRLGQALLFEQDLSCLLSLVNLIFHAVLQTQLSAINILARILSRAVRLLQLLQCFQVSGGEVLSDEPSRREDKRRDREEDSREDEAVVKQQREAVALSLNEIVKTIFTQVATANEEERQ--SSSGKGDRTGGSGDAAVPQRGTSFFSRKKGLGAHAVPSVIQHAVLYEAISLSTHLQADLSAAALLCSFVEEGDSNFRYKSLSLVAAMAAKGAVPAILRLLEEEDVSLRRQAISLLFAL.. 473
11 -10.500IDP06034 adaptin, putative [Toxoplasma gondii ME49] EEA97063 [Toxoplasma gondii ME49]  ali follow..  10  1........................................................................................................MFQSRTSLPSLIRGLRNDDEFLSASLQQIKEELVSASSPASQSLSSLLGRAPSLKLAYLQMLGVDLGFATFSVV-EAMSVQS--TLKRPAYFACALAFASPLSATSLRARENDACAREEAQDGRQLSGSGAEGRNLKQQQALSLLTTNLFKK------------------FNSKETHETSLALSTLAVMSTPEIAAALLLLLASSRSILRKKAAVCASRF-PSSFPKLRQQLMSEEETPVVTSLCSALLQRPQQYLSLVPPLFHLLCASSSNWLSLKLLKI-----------LLAPFEPRLPLKLLRPLRTLEQSRAKSVEVEILRLSLLHFPFEEAAAKARRTAAAGALLANSEVAGEEPPREDGGECELDARSCLRRIHALLTSADRNLRCVGVDILARLDVAACIKFVLQAAEECDPTIRSRGIDLLTKT.. 455
12 -9.770IDP06057 hypothetical protein jhp0260 [Helicobacter pylori J99] NP_222981 [Helicobacter pylori J99]  ali follow..  11  12............................................................................................................NLLLFSLFSCLKTLSEDHQILLSSDAFHRGDATAQKGYMNLYKQTNKVVYAKEAAISLGDIKTAMHLAMLYQKITNNRNDVSINKILVDGYAQMGQ------------------------DKAIELLHKIRKEKTIATDNVLGTLYLTQKRLDKAFPLLNKFYNQ---VHDEDSLEKLITIYFLQNRKEGLDLLQSHIDGCSEQLCQKALNTFTQFNEDLAKTTFARLYEKNPIVQNAQFYIGVLILLKEFDKAQQIAELFPFDRR--------LYTAQKKFDQASKQASLIYQERKDPKFLGLEAIYHYESLSANKKKLTKEEMLPIIQKLEQATKERQAWLAKTKDKEDAQDAFFYNFLGYSLIDYDKRGMDLVRKALALDSNS---LYLDSLAKLGNLEAKKIFSSIAKENEPELKE--NKIIQECKK 431
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Pawlowski K, Pio F, Chu Z, Reed JC, Godzik A. PAAD - a new protein domain associated with apoptosis, cancer and autoimmune diseases. Trends Biochem Sci. 2001 Feb;26(2):85-7.