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Query: IDP91695 gene: KPNA1; importin subunit alpha-1 [Homo sapiens] NP_002255 [Homo sapiens], from CSGID

Results of FFAS03 search in CSGID
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MTTPGKENFRLKSYKNKSLNPDEMRRRREEEGLQLRKQKREEQLFKRRNVATAEEETEEEVMSDGGFHEAQISNMEMAPGGVITSDMIEMIFSKSPEQQLSATQKFRKLLSKEPNPPIDEVISTPGVVARFVEFLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQAVWALGNIAGDSTMCRDYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLFVSDTDVLADACWALSYLSDGPNDKIQAVIDAGVCRRLVELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALQSLLHLLSSPKESIKKEACWTISNITAGNRAQIQTVIDANIFPALISILQTAEFRTRKEAAWAITNATSGGSAEQIKYLVELGCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQEAKRNGTGINPYCALIEEAYGLDKIEFLQSHENQEIYQKAFDLIEHYFGTEDEDSSIAPQVDLNQQQYIFQQCEAPMEGFQLLast
1 -113.000IDP91695 gene: KPNA1; importin subunit alpha-1 [Homo sapiens] NP_002255 [Homo sapiens]  ali  100  1MTTPGKENFRLKSYKNKSLNPDEMRRRREEEGLQLRKQKREEQLFKRRNVATAEEETEEEVMSDGGFHEAQISNMEMAPGGVITSDMIEMIFSKSPEQQLSATQKFRKLLSKEPNPPIDEVISTPGVVARFVEFLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQAVWALGNIAGDSTMCRDYVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLFVSDTDVLADACWALSYLSDGPNDKIQAVIDAGVCRRLVELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALQSLLHLLSSPKESIKKEACWTISNITAGNRAQIQTVIDANIFPALISILQTAEFRTRKEAAWAITNATSGGSAEQIKYLVELGCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQEAKRNGTGINPYCALIEEAYGLDKIEFLQSHENQEIYQKAFDLIEHYFGTEDEDSSIAPQVDLNQQQYIFQQCEAPMEGFQL 538
2 -22.300IDP90382 hypothetical protein [Chlamydia trachomatis D/UW-3/CX] CT_350 [Chlamydia trachomatis D/UW-3/CX]  ali follow..  9  18...................ASCDFPSSVSQRILFSCRKSVPQALEAYLEASATYQQHD------------------SVLRVIAESYLQQSFLSEDTYIRKSAIIGAGLSGSSE--------------ALELLSEAIETQDLYEQLLILNAATSQLSKT-----------SDKLLFKGLTASHPVIRLEAAYRLACM------------NSKVSDYLYSFIYKLPE-EIQNLAATIFLQL------------TEEADAYIHHLLSSPNNLTRNYVAYLIGEYK-----------QKRFLPTLRSLLTSASPLDQEGALYALGKL------------DSGSYPRIKALSSRSNPEVVLAAAQTLLFL--EKEEEALPILTNGEELLLPIFYNATQEEIRLNTALALVHQGCT----------DPQVLHYLTEILESKVLHRIFLPTHSTGKAIQFWKAMYRVAEDTILSALLKLPNDAYLPYLERILASQKTILAAKAIAFLSVTAHPQ............................... 443
3 -19.200IDP90389 hypothetical protein [Chlamydia trachomatis D/UW-3/CX] CT_384 [Chlamydia trachomatis D/UW-3/CX]  ali follow..  8  108...............................................................................DYRLVPIVLQALSDDSDTVREIAVQVAVMY--------------SSCLLRAVGDLAKNDSSIQVRITAYRAAAVLEIQDLEMLKEYPEKCTEEQIRTLLAADHPEVQVATLQIILRGGRVFR-------SSSIMESVQKLACNSLSARVQMQAAAILYLE------------DPFGEDKLTEGLSATSSILCEAASEAVCSLGIHGVHLAGRFLSKV-VNLAFALLVSREK--VEEAGDVVASFIHRIEPCREIMKRDLAKKIIRLLVAAQYSKAKMVVAQYLAGQQVGWSFCSEVFWEEGDSEDFVEPLQEESFAFALEKALSFLQREG-----------GEAGLHAVISLYPHSRWQDKLTILEAIAYS-----------------------NRIATCFLRERCLQEAASLQSAAAGAVFALFK................................. 539
4 -16.400IDP06032 beta-adaptin-like protein, putative [Toxoplasma gondii ME49] EEB01577 [Toxoplasma gondii ME49]  ali follow..  11  19.VVPRPPAGPQFFVDQKRGELYELRQVLRSLPTERDVTKQRDALKKLIAYMTVGLDVSRLFADVVMLASTADADTNPSLSLLAINTFQKDCNDEDPRLRGLALRSLCSLRLSCMLE----------YIEPAARKGASDPSPYVRRAAVMGMLKVCKLLQELMATDEEDEIRQRLHEALFDDDPQVTINAICALNELEAETG---GLQVTKKIATHFLNRIKRFSE--GVCVILNLVASYQPETEEEAFD-----VMNILDDKLKSSSAAVVLGCANCFLELTRGNAELRKQVYCR-LKPPLLTLATTGYPEIAHTILRHILLIVQTGGEDAVEIFAGES--RQLFCRYTDPSYLKATKLQTLAAIATENN--------VDMIAEIREYVCDADADIARQSLAALGVIACRIPSAA------DDVVTLLLSFVEMEADFLASAAFVILRDILRKYTKMISRLVEAIRIYALRLSDGEGVAAVVWMLGEFSKNI-DDAPYILEEIVDRFDEEPPVV........................ 516
5 -16.400IDP92583 beta adaptin protein, putative [Toxoplasma gondii ME49] TGME49_040870 [Toxoplasma gondii ME49]  ali follow..  13  3...................DGNYFQPAKRGELHELKEELHSSNKEKKKEAVKKVIAAMTVGKDVS-----------------LFPDVVNCMQTTNMELKKLVYLYVINYAKAQPELAI--------LAINTFRKDSLDPNPLIRALAVRTMGCIRLEE-------ITEYLVEPLRRSCKDPDPYVRKTAAICVAKLFSIRP---DMVGEEGFIEELTTMLSDSN-PVVVANAVAALSEISENSGRKNILNAKESNVNKLLAALNECTEWGQVFILDALAQFEPETPRAAESVLDR-----VTARLSHANSAVVLSAIKVVMKLLDKVTNPDVVRAVHRKLCPPLVTLLSAEPEIQYVALRNIELIVQKRPSILASEVK------MFFCKYNDPVYVKIEKLDILVRLVSEKNVDQ--------VLSELKEYATEVDVDFVRKAVRCIGRCAIKLDCAAE------------------VAVLLDLIQTKVNYVVQEAIVAIKDIFRKYPNQYESMIST..................... 433
6 -14.000IDP06029 adaptin N terminal region domain-containing protein [Toxoplasma gondii ME49] EEB01203 [Toxoplasma gondii ME49]  ali follow..  10  1MSLSPLMASTGPLLDRASAGMRALINIVSKSECQYFEEGHFN-----------------------------------------AAQVKKELQDASVESKVTAMKRLLAAHAGGAD--------VSALLPEVVKAI-AVPDLELKRLVYLFLIQYAEGNRDLALLSINS-----FQKDLTDRNQVVRAAALKALASIRLLE-------VVQLLVISLKRAAADCSP--VRRTAAQCVVKVFALDQDQFEE-----LKSIVLTLLADVEVSVVGAALIAFRELCLRHSHLLLHEGES-FLSNLPLLLHSESSAVVVAATAALFSLLPSATSAWQAAVH-----PLLRCMHTSAPDLQEPLLHTIAVLGSAAPSLFIPHVRS-LLTEVRTYIHWPDQALLSSSFRLLTFLALRFPG------VQAASMQTFVQLLDAPSAALAAEAVLALQTLLQRQLEQQRESSARGGQLGHLLLQL-----VSQFPRVHAPPARASVVWIVGQYFKAEAEEVKLQI....................... 666
7 -13.200IDP92606 gamma-adaptin, putative [Toxoplasma gondii ME49] TGME49_113670 [Toxoplasma gondii ME49]  ali follow..  10  1MSCKLREFIRNRAAKTAADERAVVSKECAEIRTAFKEGYRHRNVAKVLFISMLGYPTQFAQLECLKLLASPR-DEQSEVLMLATNSIKNDLQHPNQYVNGLALTALGNIGTGEMCGAIMTQVED----------LLRCSNPFIRKKAALCGVRVVKRVGDCEEKL-----LACLPALLADRNHGVLISACALITALAERDPSLVSTMRTHTLVKSLKACLTAGYAHAAEYDIALLQCRLLRALLAKGDAESSASLSDVLAHVATNTEGAKNVGNSVLYECVRTIMTIEDDPGLRVLGVNILGRFLSSRELNVKYVALGTLQQVVRVDSKAVMR-------DILLDCLKDQDLSLRRRAVEVLFCLI--TDDNVRGLVKE----LLNFLLMLNDAEFKQFVVNKIAVAASRHAPST--------QIDTLLKLMTLGGDAVDDAITYSFVDLVVSTPPLHS-----------------VVHKCYFSFQHSNAALWQAGVYCVGEF................................... 485
8 -12.800IDP06034 adaptin, putative [Toxoplasma gondii ME49] EEA97063 [Toxoplasma gondii ME49]  ali follow..  9  3......................QSRTSLPSLIRGLRAAQNDDEFLSASLQQIKEELVSASSPASQSLSSLLGRAPSASVRSTALLKLVEAMSVQSFTLKRPAYFACALAFASPLS-REEAQDGRQLSGSGAEGRNLADEKQKQQQALSLLTTNFNSKETHETSLALSTALLPDVLLLLASSRSILRKKAAVCASRFLIQVPALLPSS-----FPKLRQQLMSEEETPVVTSLCSALLQLIAERPQQYLSLVPP-LFHLLCASSSNFEPRLPLKLLRPLRTLLEQSRAKLRLSLLHFPFEEAAAKARRTAALLANSEVAGEEPPREDGGECELDAFLRSCLRRIHALLTSADRNLRCVGVDILARLFAEKRDMAADVAAC---KFVLQAAEECDPTIRSRGIDLLTKTATAESFTQ--------IAEQLVAAAGALEAQRLPGQTRSEKETGDPRSALAVAASPASASFLLPVLRM--LALLASIAVDGGESSVDSYRGRPAGAGLEEEGAEP.......................... 567
9 -12.300IDP92581 splicing factor 3a protein, putative [Toxoplasma gondii ME49] TGME49_021940 [Toxoplasma gondii ME49]  ali follow..  9  12IQDVRNAPSSSREQARVLQELSKIRQRFAHPKKPLTGYEKKKCLTKLLYIHLLGYPVD---------------------------EAISLLSSPHYSERSAAFLFCSLLLVDSHT-----SRDLPDLRSLCCSSIKKELSLQHEDFAALALDCASYSDPDAAAELFPL--MQATANPSSSASPLIRQKAYSCMLVFFRLRPSLLPCEVW---ASRLGQALLFEQDLSCLLSLVNLIFHAVLQTSQLHRWQQQ--LQLSAINILARPAPWLAVRLLQLLQCFQVSGGKREVLSDEPEIVKTIFTQVATANEEERQSSSGKGDRTGGSGDAATSFFSRKKGLGAHAVSPSVIQHAVLYEAISLSTHLQADADKDLKLSAAA----LLCSFVEEGDSNFRYKSLSLVAAMAADPDVHP----ELKGAVPAILRLLEEEDVSLRRQAISLLFALSGPDNWSE------------------IVLALLESLHRDAENISAHIAVLVETYAPDPTWLVDVAFQ...................... 524
10 -12.300IDP92584 adaptin N terminal region domain-containing protein [Toxoplasma gondii ME49] TGME49_044290 [Toxoplasma gondii ME49]  ali follow..  8  16IKAIGEARSKQEEDRIVANEIATLKVKLNEPNISQHKMQ--ELLIRSLYVELLGHDASFAHFHAVKMTNQTNNSEDNELMLLLINTIQKDLASPNILNVQSALHCVARLLTPEMLPALLPSLSS----------LLQHSHAAVRRKAVMAVHKVLDLKEREQERRVMEGLREKMRRALCDSDPSVMAVSLHVIHRLAAKNVAA------RDLVSSLVSILKQIIDRKLPKDYEWIQIKILS---AAGDQRASEEVYELLQEVMRRADAAVIYECVRTIAALYPYPK------LLDIAGCSISRFISAENNNLRYVGVTGLAAVVQVSPAYATQ-------LVVVDCLEDSDDTLKRKTLDLLVKITNPVN--------AVVVEKLLGHSRATDAHLRANLIQKIIMLAERYSPDP--------FLETILCVLEVSGPSLPLASGGNAGARRCLSGGSAGLCYSTAYSLLQLVAEG-AVNDMVALLERKKDVLMQVISWVLGEFGCYYHAGESVI........................ 564
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 0 6 7   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Pawlowski K, Pio F, Chu Z, Reed JC, Godzik A. PAAD - a new protein domain associated with apoptosis, cancer and autoimmune diseases. Trends Biochem Sci. 2001 Feb;26(2):85-7.