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Query: IDP92023 glycerol-3-phosphate dehydrogenase, putative [Toxoplasma gondii ME49] TGME49_010260 [Toxoplasma gondii ME49], from CSGID

Results of FFAS03 search in CSGID
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MEPRRPSLFQVLQSGPLKVSVVGSGNWGSVIAKIVALNAQKSYVFHNEVRMWVYEEMVDGEKLTDIINKTHENRKYLPGHKLPENLVALPDVVEACRDSDLLIFIMPHQFATKVCEQLAEARVVPGHARAITLLKGLHVENGKPTLFSDIFKTKLDIVDCCVLSGANVANDVAREEFAEATIGYSPEETDAALIWQQLFDTPYFKVNALPDVAGVQVCGAVKNVIAIAAGFCDGLGLGTNAKTAIIRLGVEEMKQFAMIFFDNIMAETFFDSAGYADVITTVFGGRNARCAAEFLRRGGKATWDQIEADLLKGQKLQGTLTTKEVYEVIAAYEVERLFPLFSVTYEIAFNGRDPNDLIRVFKTSEVRQHKTLQECNQLVVSSVVANAKEKMFGEGLPPEGREAIEAPDGSLVDEPEAKLVQQQFKLQQQLQQLQHQQQQMQQQLHIMHNNNGPLGGHRDCQSPQQLTVHLSHLTPSQRMQVHRLQQQLQYRQIHKGQDRAPSTPMGHPELGRNSLLast
1 -117.000IDP92023 glycerol-3-phosphate dehydrogenase, putative [Toxoplasma gondii ME49] TGME49_010260 [Toxoplasma gondii ME49]  ali  100  1MEPRRPSLFQVLQSGPLKVSVVGSGNWGSVIAKIVALNAQKSYVFHNEVRMWVYEEMVDGEKLTDIINKTHENRKYLPGHKLPENLVALPDVVEACRDSDLLIFIMPHQFATKVCEQLAEARVVPGHARAITLLKGLHVENGKPTLFSDIFKTKLDIVDCCVLSGANVANDVAREEFAEATIGYSPEETDAALIWQQLFDTPYFKVNALPDVAGVQVCGAVKNVIAIAAGFCDGLGLGTNAKTAIIRLGVEEMKQFAMIFFDNIMAETFFDSAGYADVITTVFGGRNARCAAEFLRRGGKATWDQIEADLLKGQKLQGTLTTKEVYEVIAAYEVERLFPLFSVTYEIAFNGRDPNDLIRVFKTSEVRQHKTLQECNQLVVSSVVANAKEKMFGEGLPPEGREAIEAPDGSLVDEPEAKLVQQQFKLQQQLQQLQHQQQQMQQQLHIMHNNNGPLGGHRDCQSPQQLTVHLSHLTPSQRMQVHRLQQQLQYRQIHKGQDRAPSTPMGHPELGRNSL 515
2 -89.900IDP92082 glycerol-3-phosphate dehydrogenase, putative [Toxoplasma gondii ME49] TGME49_107570 [Toxoplasma gondii ME49]  ali follow..  74  9..QPKRSLFQVLQKGPLRVAVIGSGNWGSVIGKICAQNAERSYVFHDQVRMWVFEEMIEGQKLTDIINQKHENVKYLPGHKLPDNLVAVPDVVEACRGADLLVFVMPHQFVAKVCDQLAKANVVPSHARAISLLKGLYVEGGRPQLFSDTIRSKLNIVECAALSGANVANDVAREEFAEATIGHSPDETDTALIWQQLFDKPYFKVNTLPDVAGVQLCGAVKNVVALAAGFCDGLGLGTNTKSAIIRLGVEEMKQFGMIFFDNVIAETFFDSAGYADVITTVFGGRNARCAAEFVRQKGSKTWDQIEAEMLNGQKLQGTLTAREVFEVISSHEVDHLFPLFTVTYDIAFKGRDPADLVRVFETREVRPHKTAEECNILVLPPLMANARRRVRVAS........................................................................................................................ 401
3 -80.500IDP01976 gene: gpsA; glycerol-3-phosphate dehydrogenase (NAD+) [Coxiella burnetii RSA 493] CBU_1518 [Coxiella burnetii RSA 493]  ali follow..  25  1...........MEPFKHPIAILGAGSWGTALALVLARKGQ-------KVRLWSYESDH-----VDEMQAEGVNNRYLPNYPFPETLKAYCDLKASLEGVTDILIVVPSFAFHEVITRMKPL--IDAKTRIAWGTKGLAKGS---RLLHEVVATELGQVPMAVISGPSLATEVAANLPTAVSLASNNSQF--SKDLIERLHGQRFRVYKNDDMIGVELCGSVKNILAIATGISDGLKLGSNARAALITRGLTEMGRLVSVFGG--KQETLTGLAGLGDLVLTCTDNQSRNRRFGL-ALGEGVDKKEAQQAI--GQAIEGLYNTDQVHALAQKHAIE--MPLTFQVHRILHEDLDPQQAVQELLERSPKAE.................................................................................................................................................. 332
4 -78.800IDP01730 gene: gpsA; glycerol-3-phosphate dehydrogenase (NAD(P)+) [Francisella tularensis subsp. tularensis SCHU S4] FTT0871 [Francisella tularensis subsp. tularensis SCHU S4]  ali follow..  26  2...............QKNILVLGAGAWGTALALQLAYRGH-------NVRINSWKAEH-----NEQMLKDNNNHKYLPSIKFPSRLKAIQDWQANIIEFDSILVATPSSGFKNTILELKEC--ILPQQNIISATKGF--CHDSYALLSEIAEDILPTTKFALLTGPSFAKELANQLPTAVVVASKDINY--ARYVQELFSNENFRCYTTTDIIGAQVGGAVKNVLAITAGIAAGMEFGVNAHAALITRGLAEIKKLGLKLGA--NSETFIGLSCLGDLLLTCSDNQSRNRRFG-LYLGQGMTIQQALKEV--NNVVEGYFTAKAVYNLAKKHNVE--MPLVFATYRILYEAADPRDIVKELMTRQLKNE.................................................................................................................................................. 331
5 -78.200IDP02668 gene: gpsA; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase [Bacillus anthracis str. `Ames Ancestor`] GBAA1526 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  31  2................TKITVVGAGSWGTALAMVLADNGH-------DVRIWGNRSEL-----MDEINTKHENSRYLPGITLPSTIVAYSSLEEALVDVNVVLIVVPTKAYREVLQDMKKY--VAGPTTWIHASKGI--EPGTSKRISEVIEEEIPEKDVVVLSGPSHAEEVGLRQATTVTSAAKRMEA--AEEVQDLFMNSYFRVYTNPDIVGVELGGALKNIIALAAGITDGLGLGDNAKAALMTRGLTEIARLGRKMGG--NPLTFAGLTGMGDLIVTCTSVHSRNWRAG-NMLGKGHSLEEVLESM--GMVVEGVRTTKAAHELAEKMEVE--MPITAALYDVLFNGNNVKDAVGSLMGRVRKHEVE................................................................................................................................................ 334
6 -70.100IDP90690 gene: gpsA; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase [Campylobacter jejuni subsp. jejuni NCTC 11168] Cj1196c [Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819]  ali follow..  24  2................MRIAVIGAGKWGSALHLALKEN--------HNCFISSLH---------------------------QRDLEDFVSIKEAL-ECEYLVFALSSQGMRAWLKENF----INKGQKILIASKGI--EDQSCQFLDEIFLDFVPKENFCVLSGPSFAAEVMQKLPTALMISGINQEL--CKKFASFF-PDFIKTYIDNDVRGAEICGAYKNVLAIASGISDGLKLGNNARAALISRGLIEMHRFGKFFGT--KEETFLGLSGAGDLFLTATSVLSRNYRVGL-KLAQNQKLDSILAEL--NEVAEGVKTAYAIEKLAKMKGIY--TPIVNEVVAI-FKGKSVQEATQNLLKQN...................................................................................................................................................... 297
7 -14.400IDP04504 2-dehydropantoate 2-reductase [Vibrio cholerae O1 biovar eltor str. N16961] VC2307 [Vibrio cholerae O1 biovar El Tor str. N16961]  ali follow..  13  1................MNIVVLGPGAVGSLWALHLHSAGH-------QVALWSRQAQ-----PTITLQLDEEAP-----------ISFRNQNLDTLIHADLLLITVKAWQVEAALQPLLP--HLNRETILLFMHNGMG---------VEAISESLTHFPVALKATLNQVSHTGFG---QTQVGPFNALGARCDFIADVFNHALAPVTWNPEIQQA-AVNCAINPLTAIHQCANG-ALVAPEFTPIITAILDEVTAVMQAEAISGEAEALR------DGVYQVIQATAANLS-------------SMHQDVFHRRPTEIDFITGYVVRKGEQHGIAT--PVNSALYQQI....................................................................................................................................................................... 286
8 -11.700IDP00140 pyrroline-5-carboxylate reductase, putative BA_0197 [Bacillus anthracis str. Ames]  ali follow..  12  1............MLTKHRILFIGAGRMAEAIFSGLLKTSKEYIE--------------------EIIVSNRSNVEKLDQLRARYNVSTTTDWKQHVTSVDTIVLAMPPSAHEELLAELSPLL---SNQLVVTVAAGISPSY---------LEERLPGGTPVAWIMPNTAAEIGKS--ISLYTMGQFVNETHQETLQLLLRGIGTSQLCTEELTAVTGSAPAFLYYFAESLIEATKSYG-------VDEATAKHLVIQMISGSASMLEQTQDPANLREQVTT.......................................................................................................................................................................................................................................... 232
9 -11.100IDP02492 gene: proC; pyrroline-5-carboxylate reductase [Francisella tularensis subsp. tularensis SCHU S4] FTT1559c [Francisella tularensis subsp. tularensis SCHU S4]  ali follow..  12  1................MKICFIGGGNMAAAMIAGMTSHGYK----------------------SQDIIVFDRNEHKCLNLIKKYNINTSTSLLNTIKLADVLILAIKPQNMFELIKNIRDT--VTSTQVIVTVAAGIQTSA---------YEELFNKEISFARTIPNTPSSLGYG--ATGIFFNKVIAADKKDLVIDIMQTMGVVTVVEDE-------KEIDIVAAISSGPAYYFQFMEHMVEAAIKQGLDK---------KQAEKLVVQTCLGAAQMALNT---------------------NENMSELRKNVTSKKGITYEALNIFEQF--------LGGIVDKAIQANIARAQQLAIEFTKLIDN................................................................................................................................................... 274
10 -10.700IDP02179 gene: proC; pyrroline-5-carboxylate reductase [Coxiella burnetii RSA 493] CBU_2090 [Coxiella burnetii RSA 493]  ali follow..  13  2..............NTSNITFIGGGNMARNIVVGLIANGYD----------------------PNRICVTNRSLDKLDFFKEKCGVHTTQDNRQGALNADVVVLAVKPHQIKMVCEELKDI-LSETKILVISLAVGVTTPL---------IEKWLGKASRIVRAMPNTPSSVRAG--ATGLFANETVDKDQKNLAESIMRAVGLVIWVSSEIAALSGSGPAYIFLIMEALQEAAEQLGLTKETA-TVLGAARMAFVTSPGGTTEQAIKVLESGNLRELFIKALTAAVNRAKELSKTVDQ........................................................................................................................................................................................................................ 274
11 -10.100IDP90757 gene: ilvC; ketol-acid reductoisomerase [Campylobacter jejuni subsp. jejuni NCTC 11168] Cj0632 [Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819]  ali follow..  14  17..............KSKKVAIIGFGSQGHAHAMNLRDNGV-------NVTIGLREGSVSAVKAKNA--------------------FEVVSVSEASKIADVIMILAPDEIQADIFNVEIKPNLSEGKAIAFAHGFNIHYGQIVVPKGVDVIMIAPKA------PGHTVRNEFTLGGGTPCLIAIHQDESKNAKNLALSYASATFKAETETDLFGEQLCGGLSALIQAGFETLVEAGYEPEMAYFECLHEMKLIVDLIYQGGIADMRYSISNTAEYGDY----------ITGPKIITEETKKAMKGVLKDIQNGVFAKDFILERRA-RMHAERKNMNDSLIEKT-------GRNLRAMMPWISAKKLVDKDK................................................................................................................................................ 339
12 -9.780IDP04467 putative nucleotide sugar dehydrogenase [Yersinia pestis CO92] YPO2174 [Yersinia pestis CO92]  ali follow..  11  1................MKVTVFGIGYVGLVQATVLAEVGHDVLCIDID-DLKKGRIAIFEPGLAPLVKENYEA----------GRLQFSTDAQAGVAHGVIQFIAVGTKYVLDVASTIGTY-MDSPKVIIDKSTVPVGTADKVHQVIQAILEQRGEKIDFSVVSNPEFLKE----RPERIVIGIDTDDSGALELISELYEP---DRMLVMDIRSAELTKYAANMLATKISFM-------NEIANIAERLGADIEKVRQGIGSDSRIGYHFIYSGCGDIQALIRTAEDKGYKPQLLQAVEQINTEFIKSHF--NSQLAGKTFAVWGLAFKPNTDDMREAPSRVVMESLWEAGATIQ................................................................................................................................................................ 355
13 -9.690IDP02330 gene: ilvC-1; ketol-acid reductoisomerase [Bacillus anthracis str. `Ames Ancestor`] GBAA1419 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  13  16..............KEKKVAIIGYGSQGHAHAQNLRDNGF-------DVVVGLRKGKSWDKAKEDGFS--------------------VYTVAEAAKQADVVMILLPDEQPEVYEEEIAPNL---QAGNSLVFAHGFNVHFDQVKPPVNVDVFLVAPKGPGHSEGGAVPALFA------VYQDATGVATEKALSYADGIGATRAGVLETTDLFGEQLCGGVTALVKAGFETLVDAGYQPELAYFECLHELKLIVDLMYEGGLENMRYSVSDTAQWGDFVSG------------VVTEDTKKAMGTVLAEIQDGTFARGKPNFYATNEKENEHEIEV---VGRKLRGMM....................................................................................................................................................................... 324
14 -9.430IDP06064 3-hydroxyacid dehydrogenase [Helicobacter pylori J99] NP_223303 [Helicobacter pylori J99]  ali follow..  13  1................MKIGWIGLGAMGTPMATRLRDAGL-------EVSVY---------------NRTESKAAPL----KEKGVAVYTSPIDLAAKVDLVFTMLSDAAIDAVL--APKFWEQMSKKIVVNMST---IAPLESLSLEKIAQKHQATYLEAPVSG---SVGAAKAGALLILAAGDEEVISKLKPVLAHLG---------------------SQTFYLGVGQGTGAKLSINSLLAQMGVAYSEALLLAKRLG--VDAESFLQIIGQSGMNSPLFQAKQDNYPAAFSLKLMAKDIRLAKNEAGEAMKLPFLFQAEELYSQAEKSGLGGL---MAAVYHYLEK..................................................................................................................................................................... 282
15 -9.090IDP02524 gene: ilvC-2; ketol-acid reductoisomerase [Bacillus anthracis str. `Ames Ancestor`] GBAA1852 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  10  1MKTYYEQDANVGLLQGKTVAVIGYGSQGHAQAQNLRDSGV-------EVVVGVRPGKSFEVAKADGFE--------------------VMSVSEAVRTAQVVQMLLPDEQQAHVYKA--EVEENLREGQMLLFSHGFNIHFGQINPPSYV--DVAMVAPKSPGHLVRRVFQEGNGVPALVAVHQDATGTALHVALAYAKGVGCTRAGVIETTFQEETETDLFGEQAVLCGGVTAL---KAGFETLTEGGYRPEIAYFECLHELKLIVDLMYEGGLTNMRHSISDTAEFGDYVTGSRIVTKKEMKRVLTEIQQGEFAKGRPTYNAMKKAEQNHQLE-----------------KVGEELREMMSWIHAPKELVKK............................................................................................................................................. 335
16 -9.050IDP05101 gene: hbd; 3-hydroxybutyryl-CoA dehydrogenase [Clostridium difficile 630] CD1058 [Peptoclostridium difficile 630]  ali follow..  13  1................MKLAVIGSGTMGSGIVQTFASCGHDVCLKSRTQGAIDKCLALLDKNLTKLVTKGKMDEATKAEIL--SHVSSTTNYED-LKDMDLIIEASVEDM-KDVFKLLDE--LCKEDTILATNTSSLSITE-----IASSTKR---------VIGMHFFNPVPMMKLVEVISGQLTSK-VTFDTVFELSKSINKVPVDVSESPGFEAVGIYADGVASKEEIDEAMKLGANHPMGPLALGLDVVLAIMNVLYTEFGDTKYRPHPLLAKMVRA--NQLGRKTKIGFYDYNK........................................................................................................................................................................................................................ 281
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Godzik A. Discovering new genes with advanced homology detection. Trends Biotechnol. 2002 Aug;20(8):315-6.