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Query: IDP92108 NADP-specific glutamate dehydrogenase, putative [Toxoplasma gondii ME49] TGME49_093180 [Toxoplasma gondii ME49], from CSGID

Results of FFAS03 search in CSGID
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MITDKNLSVVTPPELVTDDPGDMPDCKISPRCQSEASEVADPEEVDAFVKQIETANRFQPEFLQAFHEVFDSVRPVLCSNPKYLRAFKVIVEPERCITFRVPWVDDQGKQHVSRGYRVQYSSAAGPYKGGLRFHPSVTLSVMKFLGFEQIFKNSLTGLSIGGAKGGSDFDPKGRSDNEVMRFCQAFMTELSRYIGPNRDVPAGDIGVGAREIGYLFGQYKLLKAGQFEGALTGKDKNWGGSAMRPEATGYGCVYFVLELLKAQNKEGIKGMRCAISGSGNVALYAGEKLATLGAKVMTFSDSSGYIVNEKGFPLGQIQRLKEMKETRSSTRVSEFAAKYSTVKFVPDKRAWEVPCDIAFPCATQNEISEEDAQLLIDNGCRIVAEGANMPTTRDAIRLFKQHGVILCPGKAANAGGVAVSGLEMSQNAMRIEWTREVVDEKLRQIMASIFSKCRSYAAKFGENEFDLVTGANVAGFVKVADCVIDQGYILast
1 -128.000IDP92108 NADP-specific glutamate dehydrogenase, putative [Toxoplasma gondii ME49] TGME49_093180 [Toxoplasma gondii ME49]  ali  100  1MITDKNLSVVTPPELVTDDPGDMPDCKISPRCQSEASEVADPEEVDAFVKQIETANRFQPEFLQAFHEVFDSVRPVLCSNPKYLRAFKVIVEPERCITFRVPWVDDQGKQHVSRGYRVQYSSAAGPYKGGLRFHPSVTLSVMKFLGFEQIFKNSLTGLSIGGAKGGSDFDPKGRSDNEVMRFCQAFMTELSRYIGPNRDVPAGDIGVGAREIGYLFGQYKLLKAGQFEGALTGKDKNWGGSAMRPEATGYGCVYFVLELLKAQNKEGIKGMRCAISGSGNVALYAGEKLATLGAKVMTFSDSSGYIVNEKGFPLGQIQRLKEMKETRSSTRVSEFAAKYSTVKFVPDKRAWEVPCDIAFPCATQNEISEEDAQLLIDNGCRIVAEGANMPTTRDAIRLFKQHGVILCPGKAANAGGVAVSGLEMSQNAMRIEWTREVVDEKLRQIMASIFSKCRSYAAKFGENEFDLVTGANVAGFVKVADCVIDQGYI 489
2 -106.000IDP02649 putative glutamic dehyrogenase-like protein [Salmonella typhimurium LT2] STM1795 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  26  1...............................MYHGQLKNILLLSLRFIMDKLSYASDSSTSAWNTYLQQIERVAPYLGELS---PWVDTLRHPKRALIVDIPVQMDDGTIRHFEGYRVQHNLSRGPGKGGVRYHPDVDLNEVMALSAWMTIKCAALNLPYGGAKGGIRVDPFSLSEGELERLTRRYTSEIGIIIGPQKDIPAPDVGTNGKVMAWMMDTYSMNHGTTVTGVVTGKPIHLGGSLGREKATGRGVFVSGLEAARR-ANIAVEGARVAVQGFGNVGSEAARLFAGAGARVVAIQDHTATLFNATGIDMKALTAWQTEHKQI---------AGFPGAETIASDAFWRLEMDILIPAALEGQITRQRAEAL---TCKLVLEGANGPTYPDADDVLASRGILVVPDVVCNAGGVTVSYFEWVQDMASFFWSEEEINARMDKIMTDAIVHVWEKAAE---KSCSLRTAAYIVACERILLARKDRGI. 438
3 -105.000IDP02337 gene: gdhA; glutamate dehydrogenase [Bacillus anthracis str. `Ames Ancestor`] GBAA1511 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  29  2..........................................VAEKGTQTKTQQQREQHFELLNSTQIVISEALEKLGYPN---EVYELLKEPIRMMTVKIPVRMDDGTVKIFTGYRAQHNDAVGPTKGGIRFHPNVTENEVKALSIWMSLKCGIVDLPYGGGKGGIICDPREMSFRELERLSRGYVRAISQIVGPTKDIPAPDVFTNSQIMAWMMDEYSRIDEFNSPGFITGKPLVLGGSHGRETATAKGVTICIREAAKKR-DIDIKGARVVVQGFGNAGSFLAKFMHDAGAKVIAISDAYGALHDPNGLDIDYLLDRRDSFGTVTKL----------FNNTISNKELLELDCDILVPAAIENQITEENANDI---KAKIVVEAANGPTTLEATKILTDRGILLVPDVLASAGGVTVSYFEWVQNNQGYYWTEEEVEQRLEKVMVRSFDSIYETAQV---RKVNMRLAAYMVGVRKMAEASRFRGWV 428
4 -32.600IDP91367 NAD-specific glutamate dehydrogenase [Vibrio vulnificus CMCP6] VV1_2638 [Vibrio vulnificus CMCP6]  ali follow..  14  1.............................................................................................................................................MLGLVKAQQVKNTV--IVPVGAKGGFVCKRQHTMTAEGQRCYKRFIRALLDVSDNIIEVVAADKGT-----ATFSDLANSVSAEY-DAFASGGSN--GYDHKAMGITAKGGWESVKRHFREM-GIDCQTTDFTAIGVGDMAGDVFGMLLSKHIRLQAAFNHLHIFIDPNPDSASSWEERDRLFQLPRSSWEDYNPKLISKGTSLAPNELWNGGIGTYVKASSEHTDVGDRANDVRDLNAKVVGEGGNLGMTQKGRIEYALKGGRVNTDFVDNVGGVDCSDNEVNIKIFLNGLTVKQRNKILESMQDEVGDIVLDDAYRQSESVTEQQGVSVVKEQIRFIHTMEKAGYL 420
5 -7.570IDP90773 erythronate-4-phosphate dehydrogenase [Vibrio cholerae O1 biovar eltor str. N16961] VC2108 [Vibrio cholerae O1 biovar El Tor str. N16961]  ali follow..  12  48..................................................................................................................................................................................MIRSVTKVNDALLAKANRLKFVGTATAGMDHVDQALL----------------RERGIFFTAAPGCNKVGVAEYVFSVLMVLAQQQGFSVFDKTVGIIGAGQVGSYLAKCLSGIGMKVLLNDPPKQA--QGDEREFTELETLLKQADVITLHTPITRGGEWPTHHLIDAAILEQLRSDILINAARGPVVDNAALKARLQQGDGFTAVLDVFEFEPQVDMELLPLLAFATPHIAGYG........................................................................... 266
6 -7.210IDP95479 S-adenosylhomocysteinase Q5CPH1 [Cryptosporidium parvum]  ali follow..  12  184.............................................................................................................................................................YKVLKMELLKNPFRWRGMLKDLYGVSEETTTGVLRLMESEGKLLLPAINVNDSVTKSKFDNT------------------------------YGCRQSLLHGLFNGCIQMLAGKKIVVLGYGEVGKGCAQGLSGVGARVTEIDPICALQASMEGYQVSVLEDVVSEADIFITATGNKDVITVEHMRKMKENAY------IANIGHFDDEIDVYGLENYPGIKVIEVKQNVHKFTFPDTQKSV----ILLCKGRLVNATGHPPLVMSMSFTNQVLAQMDLWKSRELVDRSKNTRFFVKKLSKELDEYVARLHLDVLGIKLTKLTETQA..... 477
7 -7.120IDP02330 gene: ilvC-1; ketol-acid reductoisomerase [Bacillus anthracis str. `Ames Ancestor`] GBAA1419 [Bacillus anthracis str. `Ames Ancestor`]  ali follow..  15  15...........................................................................................................................................................................................................................................................................LKEKKVAIIGYGSQGHAHAQNLRDNGFDVVLRKGKSWDKAKEDGFSVYTVAEAAK-------------------------------QADVVMILLQPEVYEEEIAPNLQAGNSLVFAHGFN-PVNVDVFLVAPKGPGHLVRRTFSEGGAVPALFAVYQDATGVATEKALSYADGIGATRAGVLETTFKEETETDLFGEQVLCGGVTALVKAGFETLVDAGY. 218
8 -6.990IDP90820 gene: pdxB; erythronate-4-phosphate dehydrogenase [Salmonella typhimurium LT2] STM2370 [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]  ali follow..  10  36................................................................................................................................................................................NHADALMVRSVTKVNESLLSGTPVGTATAGTDHVDEAWL----------------KQAGIGFSAAPGCNAIAVVEYVFSALLMLAERDGFSLRDRTIGIVGVGNVGSRLQTRLEALGIRTLLCDPPRAA--RGDEGDFRTLDELVQEADVLTFHTPLYKDGPYKTLHLADETLIRRLKPGILINACRGPVVDNAALLARLNAGQPLSVVLDVWEGEPDLNVALLEAVDIGTSHIAGYT........................................................................... 259
9 -6.970IDP04474 gene: pdxB; putative D-isomer specific 2-hydroxyacid dehydrogenase [Yersinia pestis CO92] YPO2763 [Yersinia pestis CO92]  ali follow..  10  18.........................................................................................................................................RLGDVQAVPGRPIPRDALVDADALMVRSVTKVNEALLHGTSIG-------------------VGTATAGTDHVDDTWL----------------RQQGIGFSAAPGCNAIAVVEYVFSALMMMAERDGFQLRDKTVGIIGVGNVGSRLNARLQALGVRTLLCDPPRAD--RGDNEAFWPLEKLVREADVLTFHTPLNKTGAYQSLHMADDELLAALPDGILINACRGAVVDNAALLRALEKGKKLSVVLDVWEPEPDLSLPLLARVDIGTPHIAGYT........................................................................... 259
10 -6.820IDP04590 30S ribosomal protein S11 [Bacillus anthracis str. Sterne] BAS0136 [Bacillus anthracis str. Sterne]  ali follow..  17  33.........................................................................................................................................................................................................................TLTDTHGNALSWSSAGA-----GFRGSRKSTPFAAQMAAETAAKAAMEHGLKTLEVTVKGPGAGREAAIRALQAAGLEVTAIRDVT---VPHNGCRPPKRRRV......................................................................................................................................................................... 129
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Pawlowski K, Pio F, Chu Z, Reed JC, Godzik A. PAAD - a new protein domain associated with apoptosis, cancer and autoimmune diseases. Trends Biochem Sci. 2001 Feb;26(2):85-7.