current user: public
If you have questions about the server, please let us know.

Query: IDP00006 immune inhibitor A metalloprotease BA_0672 [Bacillus anthracis str. Ames], from CSGID

Results of FFAS03 search in H.sapiens
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
    .   10    .   20    .   30    .   40    .   50    .   60    .   70    .   80    .   90    .  100    .  110    .  120    .  130    .  140    .  150    .  160    .  170    .  180    .  190    .  200    .  210    .  220    .  230    .  240    .  250    .  260    .  270    .  280    .  290    .  300    .  310    .  320    .  330    .  340    .  350    .  360    .  370    .  380    .  390    .  400    .  410    .  420    .  430    .  440    .  450    .  460    .  470    .  480    .  490    .  500    .  510    .  520    .  530    .  540    .  550    .  560    .  570    .  580    .  590    .  600    .  610    .  620    .  630    .  640    .  650    .  660    .  670    .  680    .  690    .  700    .  710    .  720    .  730    .  740    .  750    .  760    .  770    .  780    .  790    .
# Score Template Links and tools%idFirst MRRKAPLKVLSSLAIAAIIGCTSVMSAPLAYAETPAKEKENVSTTPIDYNLIQEDRLAEALKERGTINPASSKEETKKAVEKYIEKKQGDQANKEILPADTAKEASDFVKKVKEKKMEEKEKVKKPEKNVSPEQKPEPNKKQLNGQVPTSKAKQAPYKGSVRTDKVLVLLVEFSDYKHNNIDQTPGYMYSNDFSREHYQKMLFGNEPYTLFDGSKVKTFKQYYEEQSGGSYTTDGYVTEWLTVPGKASDYGADGSSGHDNKGPKGARDLVKEALHAAAEKGLDLSQFDQFDRYDTNSDGNQNEPDGVIDHLMVIHAGVGQEAGGGKLGDDAIWSHRSKLAIDPVAIEGTKSKVDYFGGKVAAHDYTIEPEDGAVGVFAHEFGHDLGLPDEYDTKYTGTGSPVEAWSLMSGGSWTGKIAGTEPTSFSPQNKDFLQKNMGGNWAKILEVDYDKIKRGVGVPTYIDQSVTKSNRPGVVRVNLPGKSVETIKPEFGKHAYYSTRGDDMHTTLETPFFDLTKGTNAKFDYKANYELEAECDFVEVHAVTEDGTKTLIDRLGEKVVQGDKDTTDGKWIDKSYDLSQFKGKKVKLQFDYITDPAVTYKGFAMDHVNVTVDGQVVFSDDAEGQSKMNLNGFVVSDGTEKKAHYYYLEWRNYAGSDNGLKAGKGPVYNTGLVVWYADDSFKDNWVGVHPGEGFLGVVDSHPEAFVGNLNGKPTYGNTGMQIADAAFSFDQTPAWSVNSLTRGQFNYSGLQGVTTFDDSKVYSNNQIADAGRKVPKLGLKFQVVGQADDKSAGAVWIKRLast
1 -11.700sp|Q8WXS8|ATS14_HUMAN(removed signalp:1-22) A disintegrin and metalloproteinase with thrombospondin motifs 14 OS=Homo sapiens GN=ADAMTS14 PE=2 SV=2  ali   15  1..............................................................................GLAGLIRTDSTDFFIEPLERGQQEKEASGRTHVVYRREAVQQEWAEPDGDLHNEAFGLGDLPNLLGLVGDQLGDTERKRRHAKPGSYSIEVLL-VVDDSV------------RFHGKEHVQNYVLT-----------MNIVDEIYHDESLGV-HINIALVRLIMVGYRQS-----------------------LSLIERGNPSRSLEQVCRWAHSQQRQDPSHAEHH---DHVVFL-----------------------------TRQDFGPSGYAPVTGMCHPLRSCALNHEDGFSVIAHETGHVLGME--HDGQGNGCADETSLGSVMAP..................................................................................................................................................................................................................................................................................................................................................................................................... 255
2 -10.800sp|Q8TE57|ATS16_HUMAN(removed signalp:1-24) A disintegrin and metalloproteinase with thrombospondin motifs 16 OS=Homo sapiens GN=ADAMTS16 PE=1 SV=3  ali   11  1......................................................EADYFLRPLPSHLSWKLGRAAQGSSPSHVLYKRSGASEVLVTSRTWELAHQPLHSSDLRLGLPQKQHFCGRRKKYMPQPPKEDLFILPDEYKSCLRHKRSLLRSHRNEELNVETLVV--VDKKM------------QNHGHENITTYVLT-----------LNMVSALFKDGTIGG-NINIAIVGLILLEDE------------------------QPGLVISHHADHTLSSFCQWQSGLMGKDGTRHDHAILLTGLDICSWKNEPCDTLGFAPISGMCSKYRSCT----------------------------NEDTGLGTIAHESGHNFGMI--HDGEGNMCKKSEGN--IMS...................................................................................................................................................................................................................................................................................................................................................................................................... 285
3 -10.600sp|Q9Y5R2|MMP24_HUMAN Matrix metalloproteinase-24 OS=Homo sapiens GN=MMP24 PE=1 SV=1  ali   11  74..............................................................................................................................................................EAEAPFAGQNWLKSYGYLLPYDSRASALHSAKALQSAVSTMQQFYGIPVTGVLDQTTIEWMKHLSRRRRNKRYALTGQKWRQKHITYSIHNYTPK------------GELDTRKAIRQAFDVWQKVTPL----TFEEVPYHEIKSDRKEAD-IMIFFASGFHGDSSPFDGEGGFLAHAYF--------PGIGGDTHFDSDEPWTLGNANHDGNDLFLVAVHELGHALGL------EHSSDPSAI............................................................................................................................................................................................................................................................................................................................................................................................................. 299
4 -10.600sp|P59510|ATS20_HUMAN(removed signalp:1-21) A disintegrin and metalloproteinase with thrombospondin motifs 20 OS=Homo sapiens GN=ADAMTS20 PE=2 SV=2  ali   12  1..............................................................................GNEYEDGHNKPHLIYRQDLNNSFLQTLKYCSVSESQIKETSLPFHTYSNMNEDLNVMKERVLGHTSKNVPLKDERRHSRKKRLISYPRYIEIMVTADAKVVS------------AHGSNLQNYILT-----------MSIVATIYKDPSIGN-LIHIVVVKLVMIHRE------------------------EEGPVINFDGATTLK---NFCSWQQTQNDLDDVHPSHHDTAVLI---TREDICSSKEKCNML---------------GLSYLGTICDPLQSCF-----NEEKGLITIAHELGHTLGVQ--HDDNPRCKEMKVTKYHVMA...................................................................................................................................................................................................................................................................................................................................................................................................... 260
5 -10.300sp|Q9P2N4|ATS9_HUMAN(removed signalp:1-18) A disintegrin and metalloproteinase with thrombospondin motifs 9 OS=Homo sapiens GN=ADAMTS9 PE=2 SV=4  ali   13  2......................................................SGMLGTFRSHDGDYFQEDEEEQNKPHIIYPQREPSTGRHACDTSEHKNRHSKDKKKTRARKWGERINLAGDVAALNSGLATEAFSAYGNKTDNTREKRTHRRTKRFLSYPRFVEVLV-VADNRMVSYHGE---------NLQHYILTLMS-------------IVASIYKDPSIGN-LINIVIVNLIVIHNE------------------------QDGPSISFNAQTTLKNFCQWQHSKNSPGGIHH------DTAVLL---TRQDICRAHDKCDTL---------------GLAELGTICDPYRSCS-----SEDSGLSTIAHELGHVFNMP--HDDNNKCKEEGVKS-HVMA...................................................................................................................................................................................................................................................................................................................................................................................................... 295
6 -10.300sp|Q8TE60|ATS18_HUMAN A disintegrin and metalloproteinase with thrombospondin motifs 18 OS=Homo sapiens GN=ADAMTS18 PE=2 SV=3  ali   9  7................................................VAVSTCAGLSGLIRTRKNEFLHNYSSPAGHHPHVLYKRTASGRNYPGYSPSHIPHASQSRETEYHHRRLQKQHFCGRRKKYAPKPPTEDTYLRFDEYGSSGRPRRSAGKSQKGLNVETLVVA----DKKM------------EKHGKGNVTTYILT-----------MNMVSGLFKDGTIGS-DINVVVVSLILLEQE------------------------PGGLLINHHADQSLNSFCQWQSALIGKNGKRHDHAILLTGFDICSWKNEPCDTLGFAPISGMCSKYRSCT----------------------------NEDTGLGTIAHESGHNFGMI--HDGEG.................................................................................................................................................................................................................................................................................................................................................................................................................... 300
7 -10.200sp|O15072|ATS3_HUMAN(removed signalp:1-19) A disintegrin and metalloproteinase with thrombospondin motifs 3 OS=Homo sapiens GN=ADAMTS3 PE=2 SV=4  ali   12  2..................................................................................MIKSDNEEYFIEPLERGKQMEEEKGRIHVVYKRSAVEQAPIDYRESDLEGLDDLGTVYGNIHQQLNETMRRRRHAGENDYNIEVLLGV----DDSV------------RFHGKEHVQNYLLT-----------MNIVNEIYHDESLGV-HINVVLVRMIMLGYA-------------------------KSISLIERGNPS-RSLENVCRWASQQQRSDLNHSEHHDHAIFL--------------------------TRQDFGPAGMQGYAPVTGMCHPVRSCTLNHEDGFSVVAHETGHVLGME--HDGQGNRCGDETAMGSVMA...................................................................................................................................................................................................................................................................................................................................................................................................... 257
8 -9.900sp|O95450|ATS2_HUMAN(removed signalp:1-29) A disintegrin and metalloproteinase with thrombospondin motifs 2 OS=Homo sapiens GN=ADAMTS2 PE=2 SV=2  ali   14  2..................................................................................LIRMEEEEFFIEPLEKGLAAQEAEVYRRPPTSPPLGGPQALDTGASLDSLDSLSRALGVLEEHANSSRRRARRHAADDDYNIEVLLGV----DDSV------------QFHGKEHVQKYLLT-----------MNIVNEIYHDESLGA-HINVVLVRIILLSYGKS-----------------------MSLIEIGNPSQSLE---NVCRWAYLQQKPDTGHDEYHDHAIFL--------------------------TRQDFGPSGMQGYAPVTGMCHPVRSCTLNHEDGFSVVAHETGHVLGME--HDGQGNRCGDEVRLGSIMA...................................................................................................................................................................................................................................................................................................................................................................................................... 257
9 -9.700sp|Q9NPA2|MMP25_HUMAN(removed signalp:1-21) Matrix metalloproteinase-25 OS=Homo sapiens GN=MMP25 PE=1 SV=1  ali follow..  15  1...........................................................................................................................................................PKPSAQDVSLGVDWLTRYGYLPPPHPAQAQLQSPEKLRDAIKVMQRFAGLPETGRMDPGTVATMRDVLGVAGLVRRRRRYALSG--VWKKRTLTWRVRSFPQSSQLSQETVRVLMSYALMAGMESGLTFHEVDSPQGQEPDQDSYPFDGLGGT----LAHAGEHPISGDTHFDDEETWTFG------SKDGEGTDL----------------------FAVAVHEFGHALGL------GHSSAPNSI............................................................................................................................................................................................................................................................................................................................................................................................................. 229
10 -9.570sp|Q9UHI8|ATS1_HUMAN A disintegrin and metalloproteinase with thrombospondin motifs 1 OS=Homo sapiens GN=ADAMTS1 PE=1 SV=4  ali   12  37..........................................................................................RRNRQGDVGGTCGVVDDEPRPTGKAETEDEDEGTEGEDEGAQWSPQDPALQGVGQPTGTGSIRKKRFVSSHRYVETMLVA----DQSMAE------------FHGSGLKHYLLT-----------FSVAARLYKHPSIRN-SVSLVVVKILVIHDE------------------------QKGPEVTSNAALTLR---NFCNWQKQHNPPSDRDAEHYDTAILF-------------TRQDLCGSQTCDTLGMADVGTVCDPSRSCS-----------IEDDGLQTTAHELGHVFNMP--HDDAKQSLNGVNQDSHMMA...................................................................................................................................................................................................................................................................................................................................................................................................... 281
11 -9.540sp|P58397|ATS12_HUMAN(removed signalp:1-27) A disintegrin and metalloproteinase with thrombospondin motifs 12 OS=Homo sapiens GN=ADAMTS12 PE=1 SV=2  ali   13  3.................................................................................................KKHPLVEGGYHPHIVYRRQKVPETKEPTCGLKDSVNISQKQELWREKWERHNLPSRSLSRRSISKERWVETLVV--ADTKM------------EYHGSENVESYILT-----------MNMVTGLFHNPSIGN-AIHIVVVRLILLEEE------------------------EQGLKIVHHAEKTLS---SFCKWQKSINPKSDLNPVHHDVAVLL-------------TRKDICAGF--------NRPCETLGLSHLSGMCQPHRSCNINEDSGLPTIAHELGHSFGIQ--HDGKENDCEPVGRHPYIMS...................................................................................................................................................................................................................................................................................................................................................................................................... 243
12 -9.270sp|P78536|ADA17_HUMAN(removed signalp:1-17) Disintegrin and metalloproteinase domain-containing protein 17 OS=Homo sapiens GN=ADAM17 PE=1 SV=1  ali   9  1.............................................................................................................KSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLV-VADHRFYRYMGRG--------EESTTTNYLIE-----------IDRVDDIYRNTSWDN-GYGIQIEQ-IRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIA--EEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADL-------------VTTHELGHNFGAE--HDPDGLANEDQGGKY-VMYPIAVSGDHENNKMFSNCSKQSI................................................................................................................................................................................................................................................................................................................................................................................ 291
13 -9.140sp|P51511|MMP15_HUMAN(removed signalp:1-45) Matrix metalloproteinase-15 OS=Homo sapiens GN=MMP15 PE=1 SV=1  ali   12  1..............................................................................................................................................................AEDAEVHAENWLRLYGYLPQPSRHMSTMRSAQILASALAEMQRFYGIPVTGVLDEETKEWMKR--LRRRRKRYALTGRKWNNHHLTFSIQNYTEK--------GWYHSMEAVRRAFRV-------WEQATPLVFQEVPYEDIRLRRQKEAD-IMVLFASGFHGDSSPFDGTGGFLAHAYF--------PGLGGDTHFDADEPWTFSSTDLHGNNLFLVAVHELGHALGL------EHSSNPNAI............................................................................................................................................................................................................................................................................................................................................................................................................. 231
14 -9.140sp|Q9UKP4|ATS7_HUMAN(removed signalp:1-27) A disintegrin and metalloproteinase with thrombospondin motifs 7 OS=Homo sapiens GN=ADAMTS7 PE=1 SV=2  ali   11  1.................................................................................................AQPHVVYKRQAPERLAQRGDSSAPSTCGVQVYPELESRRERWEQRQQWRRPRLRRLHQRSVSKEKWVETLVVA----DAKM------------EYHGQPQVESYVLT-----------MNMVAGLFHDPSIGN-PIHITIVRLVLLEDE------------------------EEDLKITHHADNTLK---SFCKWQKSINMKGDAHPLHHDTAILL-TRKDLCAAMNRPCE--------------------TLGLSHVAGMCQPHRSCSINEDTGLPTVAHELGHSFGIQ--HDGSGNDCEPVGKRPFIMS...................................................................................................................................................................................................................................................................................................................................................................................................... 239
15 -9.120sp|Q9H324|ATS10_HUMAN(removed signalp:1-25) A disintegrin and metalloproteinase with thrombospondin motifs 10 OS=Homo sapiens GN=ADAMTS10 PE=1 SV=2  ali   13  4.....................................................................................................VYKRSSLRHPHLDTACGVRDEKPWKGRPWWLRTLKPPPARPLGNETERGQPGLKRSVSRERYVETLVVA----DKMM------------AYHGRRDVEQYVLA-----------MNIVAKLFQDSSLGS-TVNILVTRLILLTED------------------------QPTLEITHHAGKSLDSFCKWQK-SGHGNAIPENGVANHDTAVLI-------------TRYDICIYK--------NKPCGTLGLAPVGGMCERERSCSVNEDIGLATIAHEIGHTFGMN--HDGVGNSGARGQDPAKLMAA..................................................................................................................................................................................................................................................................................................................................................................................................... 247
16 -9.070sp|Q8TE56|ATS17_HUMAN(removed signalp:1-27) A disintegrin and metalloproteinase with thrombospondin motifs 17 OS=Homo sapiens GN=ADAMTS17 PE=2 SV=2  ali   15  5.................................................................................................................RKWSLTPSPSAEAQRPEQLCKVLTEKKKPTWGRPSRDWRERRNAIRLTSEHTVETLVV--ADADM------------QYHGAEAAQRFILT-----------MNMVYNMFQHQSLGI-KINIQVTKLVLLRQR------------------------PAKLSIGHHGERSLESFCHWQNLGNNQVPGGKDDPPLVDAAVFV-------------TRTDFCVHK--------DEPCDTVGIAYLGGVCSAKRKCVLAEDNGLNTIAHELGHNLGMN--HDDDHSSCAGR----HIMSGEWVKGRNPSDLSWSSCSRDDL................................................................................................................................................................................................................................................................................................................................................................................ 259
FFAS is supported by the NIH grant R01-GM087218-01
1 4 6 8 2 5   jobs submitted since Jan 1, 2011
Comments and questions to: webmaster
Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Luz JG, Hassig CA, Pickle C, Godzik A., Meyer BJ, Wilson IA. XOL-1, primary determinant of sexual fate in C. elegans, is a GHMP kinase family member and a structural prototype for a class of developmental regulators. Genes Dev. 2003 Apr 15;17(8):977-90. Epub 2003 Apr 02.