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Query: IDP00019 gene: pykA-2; pyruvate kinase BA_4843 [Bacillus anthracis str. Ames], from CSGID

Results of FFAS03 search in H.sapiens
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MRKTKIVCTIGPASESIEKLEQLIEAGMNVARLNFSHGSHEEHGARIKNIREASKKTGKTVGILLDTKGPEIRTHDFVDGQAELVTGAEVVLSTEQVLGTAEKFSVSYAGLYDDVDPGSRILIDDGLIELEVIEKADGNIRTKVLNSGTVKNKKGVNVPNVSIKLPGITEKDVKDIIFGIEQKVDFIAASFVRKAADVLEIRELLEEHNAQYIQIVPKIENQEGIDNIDSILEVSDGLMVARGDMGVEIPPEEVPLVQKRLIKKCNVLGKPVITATQMLDSMQRNPRPTRAEASDVANAIFDGTDAIMLSGETAAGQYPVEAVTMMANIAVRVEKSLQYEDMFKKRIKEFTPTITDAISQSVAHTALALDVAAIVAPTESGYTAKMISKYRPKSPIVAVTSDEQVGRRLALVWGVQAFMAEKRAASTDEMLDTAIQTGMDAGLIGLGDTVVITAGVPVAETGTTNLMKIHVVGEEVAKGQGIGRKAAKGKVVVAKTAAEAVANVNEGDILVTTSTDKDMIPAIEKAAALVVEEGGLTSHAAVVGVSIGIPVIVGVNGVTATLKNGQEVTVDAARGIVYNGHAEVLLast
1 -122.000sp|P14618|KPYM_HUMAN Pyruvate kinase isozymes M1/M2 OS=Homo sapiens GN=PKM2 PE=1 SV=4  ali follow..  44  42ARNTGIICTIGPASRSVETLKEMIKSGMNVARLNFSHGTHEYHAETIKNVRTATESFARPVAVALDTKGPEIRTGLIKGSEVELKKGATLKITLDNAKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVKQKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIRKASDVHEVRKVLGEKG-KNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETAKGDYPLEAVRMQHLIAREAEAAIYHLQLFEELRRPITSDPTEATAVGAVEASFKCCSGAIIVLTKSGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDWAEDVDLRVNFAMNVGKARGFFKKGDVVIVLTGWRPG-SGFTNTMRVVPVP................................................................................................................ 531
2 -120.000sp|P30613|KPYR_HUMAN Pyruvate kinase isozymes R/L OS=Homo sapiens GN=PKLR PE=1 SV=2  ali follow..  45  85ARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVESFARPVAIALDTKGPEIRTGILQGGEVELVKGSQVLVTVDPARGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEG-HGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAASRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQAARQVHLCRGVFPLLYREWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPG-SGYTNIMRVLSIS................................................................................................................ 574
3 -7.070sp|Q8N0X4|CLYBL_HUMAN(removed signalp:1-26) Citrate lyase subunit beta-like protein, mitochondrial OS=Homo sapiens GN=CLYBL PE=2 SV=2  ali follow..  12  42......................................................................................................................DCAVLDEDGVAANKKNEARLRIVKTLEDIDLGPTEKCVRVNSVS------SGLAEEDLETLLQSRPSSLMLPKVESPEEIQWFADKFSFHLKGPMNLIPFVETAMGLLNFKAVCEETDAVVFGGEDFRASIGATDILYARQKIVVIAKAFG---LQAIDLVYIDFRDGAGLLRQSREGAAMGFTGKQVI----------HPNQ-IAVVQEQFSPSPEKIKWAEELIAAFKEHQQLGKGAFTFQGSMIDMPLLKQAQNTVTLATSIKEK....................................................................................................................................................................................................... 314
4 -6.660sp|Q9NQ75|CASS4_HUMAN Cas scaffolding protein family member 4 OS=Homo sapiens GN=CASS4 PE=1 SV=2  ali   12  73............................................................................................................................................................................................................................SEHCRLYFGALFKAISAFHGS-----LSSSQPAEIITQSKLV---------IMVGQKLVDTLCMEERDVRNEILRGSSHLCSLLKDVALATKNAVLTYPPAALGHLQAEAEKLEQHTR....................................................................................................................................................................................................................................................... 179
5 -6.270sp|Q99558|M3K14_HUMAN Mitogen-activated protein kinase kinase kinase 14 OS=Homo sapiens GN=MAP3K14 PE=1 SV=2  ali   13  16.........................................................................................................................................................................................NIFMELLEGGS----LGQLVKEQGCLPEDRALYYLGQEGLEYLDNVLLSSDGSHAALCDFGHAVCLQPD--LGKSLLTGDYIPGTETHMAPEVVLG---RSCDAKVDVWSSCCMML----------HMLNGCHPWTQFFRGPLCLKIASEPPPVREIPPSCAPLTAQAIQEGLRKEPIHSAAELGGKVNRALQQVGGLK......................................................................................................................................................................................................... 212
6 -6.060sp|P63145|GAK11_HUMAN HERV-K_22q11.21 provirus ancestral Gag polyprotein OS=Homo sapiens PE=1 SV=2  ali   11  159.......................................................................................................................................................................................................................................................SFSIKML----KDMKEGVKQYGPNSPYMRTLLDSIAYGHRLIPYDWEILAKSSLSPSQFLQFKTWWID------QEQVRRNRAANPPVNIDADQLLGIGQNWSTISQQALMQNEAIEQVRAICLRAWEKIQDPGSACPSFNTVRSKEP.............................................................................................................................................................................................. 300
7 -5.950sp|Q9UK00|CC018_HUMAN Uncharacterized protein C3orf18 OS=Homo sapiens GN=C3orf18 PE=2 SV=2  ali follow..  18  57.................................................................................................................................................................................................AGVGTMLLSFGIITVIGLAVALVLYIRKKKRLEKLRHQL-----MPMYNFD-----PTEEQDELEQELLEHGRDASVQAMQGKTTLPSQGPLQRPSRLVFTDVANAI............................................................................................................................................................................................................................................................................................. 160
8 -5.940sp|P87889|GAK10_HUMAN HERV-K_5q33.3 provirus ancestral Gag polyprotein OS=Homo sapiens PE=1 SV=4  ali   11  159.......................................................................................................................................................................................................................................................SFSIKML----KDMKEGVKQYGPNSPYMRTLLDSIAYGHRLIPYDWEILAKSSLSPSQFLQFKTWWID------QEQVRRNRAANPPVNIDADQLLGIGQNWSTISQQALMQNEAIEQVRAICLRAWEKIQDPGSTCPSFNTVRSKEP.............................................................................................................................................................................................. 300
9 -5.890sp|Q9Y2Y6|TMM98_HUMAN(removed signalp:1-21) Transmembrane protein 98 OS=Homo sapiens GN=TMEM98 PE=2 SV=1  ali follow..  12  1...........................................................................................................................................................................................ALVLVCRQRYCRPRDLLQRYDSKPIVDLIGAMETEPSELELDDVVITNPHIEAILENEDWIEDASGLMSHCIAILKICHTLTEKLVAMTASVSDIIVVAKRISPRVDDVVKSMYPPLDPKLLDARTTALLLSVSHLVLVTRNACHLTGGLDWIDQSLSAAEEHLEVLREAALASE............................................................................................................................................................................................................................... 187
10 -5.780sp|Q9YNA8|GAK3_HUMAN HERV-K_19q12 provirus ancestral Gag polyprotein OS=Homo sapiens PE=1 SV=3  ali   11  159.......................................................................................................................................................................................................................................................SFSIKML----KDMKEGVKQYGPNSPYMRTLLDSIAHGHRLIPYDWEILAKSSLSPSQFLQFKTWWID------QEQVRRNRAANPPVNIDADQLLGIGQNWSTISQQALMQNEAIEQVRAICLRAWEKIQDPGSTCPSFNTVRSKEP.............................................................................................................................................................................................. 300
FFAS is supported by the NIH grant R01-GM087218-01
1 4 6 8 2 5   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Luz JG, Hassig CA, Pickle C, Godzik A., Meyer BJ, Wilson IA. XOL-1, primary determinant of sexual fate in C. elegans, is a GHMP kinase family member and a structural prototype for a class of developmental regulators. Genes Dev. 2003 Apr 15;17(8):977-90. Epub 2003 Apr 02.