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Query: IDP04465 hypothetical protein [Yersinia pestis CO92] YPO1994 [Yersinia pestis CO92], from CSGID

Results of FFAS03 search in H.sapiens
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MLLNNITPVNKSLTLQDLLGILSHSSAISNVANGIYVESEILEVGSWLSAYAANKDEIFSQIITELENPYQFQLENDIQAPSFILYSNERITIRLVMWLPLQGKLDRTPYSYEEAHDHNFDFWTVNFFGGGYRTRLYDYDYDKVSGVNNEVVELNCYGDKILSPNTVMFYFRSKDVHTQYPPDELSVSLNLIVRPIKSKHQYEFQIDSDALEGKIEARIKKGRYERYAFQNVLYNGLLSLENEKSRQLVHKVSLCNHREEIRLIAYEALLKHAQKKGNVSDIKSISEQAFKDQSLYIKNKISHSIGSMPCMSPKPRLast
1 -22.900sp|Q16878|CDO1_HUMAN Cysteine dioxygenase type 1 OS=Homo sapiens GN=CDO1 PE=1 SV=2  ali follow..  19  1ME---QTEVLKPRTLADLIRILHQLFA--------GDEVNVEEVQAIMEAYESDPTEWAMYA----------KFDQYRYTRNLVDQGNGKFNLMILCWGEGHG---------SSIHDHNSHCFLKMLQGNLKETLFAWPD--------KKSNEMVKKSERVLRENQCAYINDSIGLHRVENISHTEPAVSLHLYSPPFDTCHAFDQRTGHKNKV...................................................................................................... 177
2 -19.300sp|Q9Y4F9|FA65B_HUMAN Protein FAM65B OS=Homo sapiens GN=FAM65B PE=1 SV=4  ali   6  7....................................................................................................................................................................................................................ARQVSMVQTLQSLRDEKLLQTMSDLAPSNLLAQQEVLRTLALTREDNEVSEAVTLYLAAASKNQHFREKALLYYCEALTKTNLQLQKAACLALKILEATESIKM 112
3 -19.100sp|Q6ZS17|FA65A_HUMAN Protein FAM65A OS=Homo sapiens GN=FAM65A PE=1 SV=1  ali   4  15....................................................................................................................................................................................................................AEEVLLVRNLNSDDQAVVLKALRLAPEGRRRDGLRALSSL-LVHGNNKVMAAVSTQLRSLSLGPTFRERALLCFLDQLEDEDVQTRVAGCLALGCIKAPEGIEP 118
4 -18.200sp|Q99460|PSMD1_HUMAN 26S proteasome non-ATPase regulatory subunit 1 OS=Homo sapiens GN=PSMD1 PE=1 SV=2  ali   14  1.......................................................................................................................................................................................................................RLLHVAVSDVNDDVRRAAVESLGFILPEQCPSVVSLLS-ESYNPHVRYGAAMALGICCAGTGNKEAI-NLLEPMTNDPVNYVRQGALIASALIMIQQT... 99
5 -17.600sp|Q9BU89|DOHH_HUMAN Deoxyhypusine hydroxylase OS=Homo sapiens GN=DOHH PE=1 SV=1  ali follow..  13  159......................................................................................................................................................................................GRLREALLDESRPLFERYRAMFALRNAGGEEAALALAEGLHCGSALFRHEVGYVLGQLQHEAAVPQLAALARCTENPMVRHECAEALGAIARPAC-----LAALQAHADDPERVVRESCEVALDMYEHETGRA. 287
6 -17.600sp|P42345|MTOR_HUMAN Serine/threonine-protein kinase mTOR OS=Homo sapiens GN=MTOR PE=1 SV=1  ali   12  153.....................................................................................................................................................................................................................VRHCADHFLNSEHKEIRMEAARTCSRLLTPDVLSKLLVVGITDPDPDIRYCVLASLDERFDAHLAQAENLQALFVALNDQVFEIRELAICTVGRLSSMNPA.. 274
7 -17.600sp|Q96MK2|FA65C_HUMAN Protein FAM65C OS=Homo sapiens GN=FAM65C PE=2 SV=4  ali   7  40.........................................................................................................................................................................................................................LIEELHCAGQAKVVRKLQGKRLGQLQPLPQTLRAWAQLDGTPRVCRAASARLAGAVRNRSFREKALLFYTNALAENDARLQQAACLALKHLKGIESIDQ 140
8 -17.400sp|Q96MK2|FA65C_HUMAN Protein FAM65C OS=Homo sapiens GN=FAM65C PE=2 SV=4  ali   7  190.........................................................................................................................................................................................................................LIEELHCAGQAKVVRKLQGKRLGQLQPLPQTLRAWAQLDGTPRVCRAASARLAGAVRNRSFREKALLFYTNALAENDARLQQAACLALKHLKGIESIDQ 290
9 -17.300sp|Q9NRP7|STK36_HUMAN Serine/threonine-protein kinase 36 OS=Homo sapiens GN=STK36 PE=1 SV=2  ali   10  101...................................................................................................................................................................................................................SGLLSLLLLGLGDKDPVVRCSASFAVGNAAYAAAVPSMTQL-LGDPQAGIRRNVASALGNLGPEGLQCEVPQRLLEMACGDPQPNVKEAALIALRSLQQEPGIHQ 218
10 -17.000sp|Q6ZS17|FA65A_HUMAN Protein FAM65A OS=Homo sapiens GN=FAM65A PE=1 SV=1  ali   10  196...................................................................................................................................................................................................................RDGLRALSSLLVHGNNKVMAAVSTQLRSLSRERALLCFLD-QLEDEDVQTRVAGCLALGCIKAPEGIEP-----LVYLCQTDTEAVREAARQSLQQCGEEGQ... 296
11 -16.900sp|Q96HW7|INT4_HUMAN Integrator complex subunit 4 OS=Homo sapiens GN=INTS4 PE=1 SV=2  ali   10  2VDVACKHLTDTSHGVRKCLQLLGNLGSLEKSVTKDAEGLAARDVQKIIGDYFSDQD-VRTAAIKAMLQERGLKLHQTIYNQACKLLSDDYEQVRSAA--------------------------LIWVVSQLYPESIVPIPSSNEEIRLVDDA-FGKICHMVSDGSWVVRVQAAKLLGSMEQVSSHFLEQTLDKKLMSDLRRKRTAHERAKELYSSGEFSSGRKWGDDAPKEEVDTGAVNLIESGACGAFVH-GLEDEMYEVRIAAVEALCMLAQSSPSAEKCLDFLVDMFNDEIEEVRLQSIHTMRKISNNITLRE 296
12 -16.800sp|Q96HW7|INT4_HUMAN Integrator complex subunit 4 OS=Homo sapiens GN=INTS4 PE=1 SV=2  ali   11  1..........................................................................................................................................................................QAAKLLGSMEQVSSHFLEQTLDKKLMSDLRRKRTAHERAKELYSSGEFSSGRKWGDDAPKEEVDTGAVNLIESGACGAFVH-GLEDEMYEVRIAAVEALCMLAQSSPSAEKCLDFLVDMFNDEIEEVRLQSIHTMRKISNNITLRE 146
13 -16.800sp|Q9Y4F9|FA65B_HUMAN Protein FAM65B OS=Homo sapiens GN=FAM65B PE=1 SV=4  ali   6  157....................................................................................................................................................................................................................ARQVSMVQTLQSLRDEKLLQTMSDLAPSNLLAQQEVLRTLALTREDNEVSEAVTLYLAAASKNQHFREKALLYYCEALTKTNLQLQKAACLALKILEATESIKM 262
14 -16.300sp|Q9BPX3|CND3_HUMAN Condensin complex subunit 3 OS=Homo sapiens GN=NCAPG PE=1 SV=1  ali   8  1.............................................................................................................................................................................................................................LKDKIPNVRIQAVLALSRLQDPKVVNAYATLIENDSNPEVRRAVLSCI-------APSAKTLPKIVGRTKDVKEAVRKLAYQVLAEKVHMRAMS. 92
15 -16.200sp|Q6ZQQ6|WDR87_HUMAN WD repeat-containing protein 87 OS=Homo sapiens GN=WDR87 PE=2 SV=3  ali   13  1........................................................................................................................................................................................................................................CVGALGQIFASETARRLLN-DTTNSNPLIRELAWEGLKRLGMIT---HLFAMPLAQGLMDKDERVRIKTLSLMAEIGIHSR... 86
16 -16.200sp|Q6PJG6|BAAT1_HUMAN BRCA1-associated protein required for ATM activation protein 1 OS=Homo sapiens GN=BAAT1 PE=1 SV=2  ali   15  161............................................................................................................................................................................................................GSSPTVLKKAFQATLRWLLSSPKTPGCSDLGPLIPQFLRELFPVLQK-RLCHPCWEVRDSALEFLTQLSRHWGGASEVPQLALQLLQDPESYVRASAVTAMGQLSSQGLH.. 278
17 -16.100sp|P30154|2AAB_HUMAN Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform OS=Homo sapiens GN=PPP2R1B PE=1 SV=3  ali   11  37..............................................................................................................................................................................................................TEWAQNTIVPKVLVMANDPNYLHRMTTLFCINALSEKQMLPIVLKMA-GDQVANVRFNVAKSLQKIGDTNALQGEVKPVLQKLGQDEDMDVKYFAQEAISVLALA..... 151
18 -15.700sp|Q96SZ5|AEDO_HUMAN 2-aminoethanethiol dioxygenase OS=Homo sapiens GN=ADO PE=1 SV=2  ali follow..  10  1MP-----RDNMASLIQRIARQACLTFRGSGGGRQPGFPENLSKLKSLLTQLRAE-----DLNIAPRKATLQPLPPNLPPVTYMHIYETDGFSLGVFLLKSGTS----------PLHDHGMHGMLKVLYGT-VRISCMDKLDAGGGQRPRALGVLRSRAEYTEASGPCILTPHRDNLHQIDAVEGPAAFLDILAPP......................................................................................................................... 211
19 -15.600sp|Q6PJG6|BAAT1_HUMAN BRCA1-associated protein required for ATM activation protein 1 OS=Homo sapiens GN=BAAT1 PE=1 SV=2  ali   15  1.........................................................................................................................................................................................AVLLECLESP---------GSSPTVLKKAFQATLRWLLSSPKTPGCSDLGPLIPQFLRELFPVLQK-RLCHPCWEVRDSALEFLTQLSRHWGGASEVPQLALQLLQDPESYVRASAVTAMGQLSSQGLH.. 128
20 -15.500sp|Q99460|PSMD1_HUMAN 26S proteasome non-ATPase regulatory subunit 1 OS=Homo sapiens GN=PSMD1 PE=1 SV=2  ali   12  142..............................................................................................................................................................................................................GSGNNKAIRRLLHVAVSDVNDDVRRAAVESLGFILTPEQCPSVVSLLSESYNPHVRYGAAMALGICCAGTGNKEAI-NLLEPMTNDPVNYVRQGALIASALIMIQQT... 249
21 -15.300sp|Q6ZQQ6|WDR87_HUMAN WD repeat-containing protein 87 OS=Homo sapiens GN=WDR87 PE=2 SV=3  ali   12  124.............................................................................................................................................................................................................MSEITINSMIETMLNIMVHASLLKYQCCVGALGQIFASETARRLLN-DTTNSNPLIRELAWEGLKRLGMIT---HLFAMPLAQGLMDKDERVRIKTLSLMAEIGIHSR... 236
22 -15.100sp|Q86WZ0|HEAT4_HUMAN HEAT repeat-containing protein 4 OS=Homo sapiens GN=HEATR4 PE=1 SV=1  ali   9  81...................................................................................................................................................................................................................AKLLPSFLHCFSDDFTAVRRAACLAAGALQDKMVLECLLNLMQRDPYWKIKAFAIRALGQIGQ--VSPELTDLLLWAIHYEESPGVRLEACRSILALKLQGD... 182
23 -15.100sp|Q6AI08|HEAT6_HUMAN HEAT repeat-containing protein 6 OS=Homo sapiens GN=HEATR6 PE=1 SV=1  ali   17  182..............................................................................................................................................................................................................................NSEHPTLQASACDALSSILPMLCITVLLGLN-DSKNRLVKAATSRALGVYRQDVIFVADAANAILMSLEDKSLNVRAKAAWSLGNLTD...... 285
24 -14.800sp|Q86WZ0|HEAT4_HUMAN HEAT repeat-containing protein 4 OS=Homo sapiens GN=HEATR4 PE=1 SV=1  ali   11  181...................................................................................................................................................................................................................EVLLPALEAALCDKNAHVRMAAAICQYAIQNPLARNIMQT-ALLKGNSVDSWAAAQCLALEGT--ATYPVIKRILHQLFTKKNEDTEEQSYILLSYLSEKTTL.. 282
25 -14.600sp|Q86WZ0|HEAT4_HUMAN HEAT repeat-containing protein 4 OS=Homo sapiens GN=HEATR4 PE=1 SV=1  ali   11  195................................................................................................................................................................................................................SLGKEVHDIIRVKLGQGNSQERVEALYLIGELKTAKLLPSFLH-CFSDDFTAVRRAACLAAGALQI--RDKMVLECLLNLMQRDPYWKIKAFAIRALGQIGQVSP... 298
26 -14.600sp|Q6PJG6|BAAT1_HUMAN BRCA1-associated protein required for ATM activation protein 1 OS=Homo sapiens GN=BAAT1 PE=1 SV=2  ali   10  1.............................................................................................................................................................................................................................SVDSEGFPRRAVMQVFTEW--EQFVATVLQAASRDLDWEVRAQGLELALVFLGQTLGPPRLFDFAFCALFDCDRPVAQKSCDLLLFLRD...... 128
27 -14.400sp|Q96LV5|IN4L1_HUMAN Integrator complex subunit 4-like protein 1 OS=Homo sapiens GN=INTS4L1 PE=2 SV=1  ali follow..  17  163...................................................................................................................................................................................................................SGACGAFVHGLEDEMYEVRIAAVEALCMLAQEKCLDFLVDM-FNDEIEEVRLQSIHTMRKISNNITLREDQLDTVLAVLEDSSRGIREALHELLCCTN....... 265
28 -14.400sp|Q96HW7|INT4_HUMAN Integrator complex subunit 4 OS=Homo sapiens GN=INTS4 PE=1 SV=2  ali   11  149...................................................................................................................................................................................................................MRLVDVACKHLTDTSHGVRNKCLQLLGNLGARDVQKIIGDYF-SDQDPRVRTAAIKAMLQLHERGLKHQTIYNQACKLLSDDYEQVRSAAVQLIWVVSQLYP... 264
29 -14.200sp|Q9P260|K1468_HUMAN LisH domain and HEAT repeat-containing protein KIAA1468 OS=Homo sapiens GN=KIAA1468 PE=1 SV=2  ali   6  1.....................................................................................................................................................................................................................LLPQCWEQINHKYPERRLLVAESCGALASSLVLSMLQQMLMEDKADLVREAVIKSLGIIMDDPDKYHQGFELLLSALGDPSERVVSATHQVFLPA........ 106
30 -13.900sp|Q2T9F4|IN4L2_HUMAN Integrator complex subunit 4-like protein 2 OS=Homo sapiens GN=INTS4L2 PE=2 SV=1  ali follow..  16  163...................................................................................................................................................................................................................SGACGAFVHGLEDEMYEVRIAAVEALCMLAQEKCLDFLVDM-FNDEIEEVRLQSIHTMRKISNNITLREDQLDTVLAVLEDSARDIREALHELLCCTN....... 265
31 -13.800sp|P42695|CNDD3_HUMAN Condensin-2 complex subunit D3 OS=Homo sapiens GN=NCAPD3 PE=1 SV=2  ali   10  90...................................................................................................................................................................................................................RCVMAMLRRRIRDEKTNVRKSALQVLVSI-MKEDLWILQDQC-RDPAVSVRKQALQSLTELLMAQPRCVQIQKAVVPVVMDCESTVQEKALEFLDQL........ 196
32 -13.800sp|A6NES4|HTRB1_HUMAN HEAT repeat-containing protein 7B1 OS=Homo sapiens GN=HEATR7B1 PE=4 SV=3  ali   10  12..................................................................................................................................................FDNESELLRLKAFILF--GKLARVVGMSKFKGEVKKAWIPLMLHSQDPCSNAAQACMATMFQKSLEHPSGPSDTATDDKMTVFQTTMCSILTRKKPAVLYRFLLETMVKNNLSRIRIAACNLAGIIMKKKLDFPALRNSLQELQLDPDPGVRRAALETLTVLDSCSQ... 195
33 -13.700sp|Q13200|PSMD2_HUMAN 26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens GN=PSMD2 PE=1 SV=3  ali   11  155....................................................................................................................................................................................NVLKVQQLLHICSEHFDSEKEEDKDKKEKKDKDKKEAPADMGAHQGVAVLGIALIAMGEEIGAEMALRTFGHLLRYGEPTLRRAVPLALALISVSNPRLN-ILDTLSKFSHDADPEVSYNSIFAMGMVGSGTNNAR 290
34 -13.700sp|Q6AI08|HEAT6_HUMAN HEAT repeat-containing protein 6 OS=Homo sapiens GN=HEATR6 PE=1 SV=1  ali   15  32..............................................................................................................................................................................................................................NSEHPTLQASACDALSSILPMLCITVLLGLN-DSKNRLVKAATSRALGVYVLDVIFVADAANAILMSLEDKSLNVRAKAAWSLGNLTD...... 135
35 -13.500sp|Q9NRP7|STK36_HUMAN Serine/threonine-protein kinase 36 OS=Homo sapiens GN=STK36 PE=1 SV=2  ali   12  131......................................................................................................................................................................................ELPISLLTRLALMDPTSLNQFVNTVSASPRTIVSFLSVALLSDQPLLTSDLLSLLAHTGSDESYRPLRSL-LGHPENSVRAHTYRLLGHLLQHSMSQSGLLSLLLLGLGDKDPVVRCSASFAVGNAAYAAAVP. 295
36 -13.400sp|P30154|2AAB_HUMAN Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform OS=Homo sapiens GN=PPP2R1B PE=1 SV=3  ali   8  21LGENLPIEDRETIIMNQILPYIKELVSDTNQHVKSALASVIMGLSTILGKENTIEHLL-PLFLAQLKDECPDVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSL-------LVDHVYAIREAATNNLM-----------KLVQKFGTEWAQNTI-------------------------VPKVLVMANDPNYLHRMTTLFCINALSEKQMLPIVLKMA-GDQVANVRFNVAKSLQKIGDTNALQGEVKPVLQKLGQDEDMDVKYFAQEAISVLA....... 299
37 -13.300sp|Q5VYK3|ECM29_HUMAN Proteasome-associated protein ECM29 homolog OS=Homo sapiens GN=ECM29 PE=1 SV=2  ali   7  42...................................................................................................................................................................................................................QSATETIGSFLDSTSPLLAIAACTALGEIGRNGPLPLLSRIPSSKETNKMKERAIQTLGYFPGDFPHQKLLLQGLMDSVEAKQIELQFTIGEAITSAAIGTSSV. 164
38 -13.300sp|Q86XA9|HTR5A_HUMAN HEAT repeat-containing protein 5A OS=Homo sapiens GN=HEATR5A PE=1 SV=2  ali   8  135...................................................................................................................................................................................................................TDTVGNILKAMKSAESQGRYEIMLSLQNILNRDVYKAARS-CLTDRSMAVRCAAAKNEAIFMWSTDL-DSVATLCFKSFEGSNYDVRISVSKLLGIILAKAVISK 247
39 -13.300sp|Q9BPX3|CND3_HUMAN Condensin complex subunit 3 OS=Homo sapiens GN=NCAPG PE=1 SV=1  ali   11  134............................................................................................................................................................................................................QIDDDVFDKINKAMLIRLKDKIPNVRIQAVLALSRLQDPKVVNAYATLIENDSNPEVRRAVLSCI-------APSAKTLPKIVGRTKDVKEAVRKLAYQVLAEKVHMRAMS. 242
40 -13.100sp|Q9P2D3|HTR5B_HUMAN HEAT repeat-containing protein 5B OS=Homo sapiens GN=HEATR5B PE=1 SV=2  ali   10  135...................................................................................................................................................................................................................PETVNNLLKSLKSAESQGRSEILMSLQKVLSRDIYKNARS-LLTDRSMAVRCAVAKCLLELQNETAELENIATLCFKALENSNYGVRVAVSKLLGTVMATALMPK 253
41 -13.000sp|Q6P1X5|TAF2_HUMAN Transcription initiation factor TFIID subunit 2 OS=Homo sapiens GN=TAF2 PE=1 SV=3  ali   12  44.........................................QADFMWQYQLRYERDVVAQQ--ESILALEKFPTPASRLALTDILEQEQCFRVRMSACFCLAKIANSMVSTW----------TGPPAMKSLFTRMFCCKSCPNIV----KTNNFMSFQSYFLQKTMPVAMALLRDVHNLCPKEVLTFILDLIKYNDNRKNKFS---DNYYRAEMIDALANSVTPAVSVNNEVRTLDNLNPDVRLILEEITRFLNMEKRHTITVSCLRAIRVLQKNGHVPSDPALFKSYAEYGHFVDIRIAALEAVVDYTKV..... 300
42 -12.800sp|Q6NXR2|STG31_HUMAN STAG3-like protein OS=Homo sapiens GN=STAG3L1 PE=2 SV=2  ali follow..  8  11..........................................................................................................................................................................................................................KVTCRDVLPEIRAICIEEIGCWMQSYSTSFLTD-TLHDKHREVRVKCVKALKGLYGNRDLTARLELFMVSMIVDREYSVAVEAVRLLILI........ 114
43 -12.800sp|Q14974|IMB1_HUMAN Importin subunit beta-1 OS=Homo sapiens GN=KPNB1 PE=1 SV=2  ali   13  196...................................................................................................................................................................................................................................KAAGVCLMLLATCCEDDIVPHVLPFIIKNPDWRYRDAAVMAFGCILEGPEPSIQAMPTLIELMKDPSVVVRDTAAWTVGRICE...... 287
44 -12.600sp|Q13535|ATR_HUMAN Serine/threonine-protein kinase ATR OS=Homo sapiens GN=ATR PE=1 SV=3  ali   16  25.............................................................................................................................................................................................................................SDSYSPQAQSRCVFLLTLFPRRIFLEWRTAVALQSSHEVIRASCVSGFFILLQQQNSCNRVPKILIDKVKDDSDIVKKEFASILGQLVCTLH... 119
45 -12.600sp|Q92616|GCN1L_HUMAN Translational activator GCN1 OS=Homo sapiens GN=GCN1L1 PE=1 SV=6  ali   9  4...........................................................................................................................................................................................................FCLPKKGVTSILPVLREGVLTGSPEQKEEAAKALGLVIRVSITGPLIRILGDRFSWNVKAALLETLSLLLAKVGIAPQLQTTFTKALQDSNRGVRLKAADALGKLISIHI... 129
46 -12.600sp|P42695|CNDD3_HUMAN Condensin-2 complex subunit D3 OS=Homo sapiens GN=NCAPD3 PE=1 SV=2  ali   10  4.....................................................................................................................................................................................................................SQPPPQVRGSVMPSVIRAHAIITLGKL--KKSIPALVRELEVCEDVAVRNNVIIVMCDLCIRYTIVDKYIPNISMCLKDSDPFIRKQTLILLTNL........ 105
47 -12.600sp|O75155|CAND2_HUMAN Cullin-associated NEDD8-dissociated protein 2 OS=Homo sapiens GN=CAND2 PE=1 SV=3  ali   8  120..................................................................................................................................................LGSPSEDVRAAASYALGRVGAGSLPDFLPFLLEQIEAEPRRQYLLLHSLREALGAAQPDSLKPYAEDIWALLFQRCEGAEEGTRGVVAECIGKLVLVNPSFLLPRLQLAAGRPHTRSTVITAVKFLISDQPHPKSFIGEFMESLQDPDLNVRRATLAFFNSAVHNKP... 293
48 -12.400sp|P42695|CNDD3_HUMAN Condensin-2 complex subunit D3 OS=Homo sapiens GN=NCAPD3 PE=1 SV=2  ali   6  14.....EGSHRAPLAVTSQVINCRNQAVQ-SALVDELKESIFPVVRILLQHICAKRTFAAQSLVQ-LLSKLPCGEYAMFIAWLYKYSRSSKIPHRVFT-------------------------VVLALLELPEREVDNTLSLEHQKFLKHKFLVQEIMFDRCLDKAPTVRSKALSSFAHCLELTVTSASESILSPTFSVIESHPGTLLRNSSAFSYQRQTSNRSEPSGEINIDSSGETVGSGERCVMAMLRR-RIRDEKTNVRKSALQVLVSILKHCDVSKEDLWILQDQCRDPAVSVRKQAL.............. 300
49 -12.400sp|O75533|SF3B1_HUMAN Splicing factor 3B subunit 1 OS=Homo sapiens GN=SF3B1 PE=1 SV=3  ali   10  157...................................................................................................................................................................................................................ATMISTMRPDIDNMDEYVRNTTARAFAVVGIPSLLPFLKAVCKSKKSWQARHTGIKIVQQIAILMGCARSLVEIIEHGLVDEQQKVRTISALAIAALAE...... 264
50 -12.400sp|Q92616|GCN1L_HUMAN Translational activator GCN1 OS=Homo sapiens GN=GCN1L1 PE=1 SV=6  ali   11  177...............................................................................................................................................................................................................AFAEQEEVDVLLCALQSPCASVRETVLRGLMELHMVLPLNLLRRLVKFDKEEEIRKLAERLWSMMG--LDLQPDLCSLLIDDVIYHEAAVRQAGAEALSQAVARYQ... 291
51 -12.300sp|Q9P2D3|HTR5B_HUMAN HEAT repeat-containing protein 5B OS=Homo sapiens GN=HEATR5B PE=1 SV=2  ali   12  1...................................................................................................................................................................................................................................QGRSEILMSLQKV-ASSHRDIYKNALLTDRSMAVRCAVAKCLLELQNETAELENIATLCFKALENSNYGVRVAVSKLLGTV........ 95
52 -12.300sp|Q8NDA8|HTR7A_HUMAN HEAT repeat-containing protein 7A OS=Homo sapiens GN=HEATR7A PE=1 SV=3  ali   9  85.........................................................................................................................................................VHLVESWDLRSGLLHVAIRIRPFFDSEKMEFRTASIRLFGHLNKVCHGDCEDVFLDQVVGGLAPLLLHLQDPQATVASACRFALRMCGPNLACEELSAAFFKSSWENVRAAAPLFTGFLVLHSEPRDQLIAALQILLKDPAPEVRTRAAEALGRLVKLA.... 291
53 -12.200sp|Q68CQ1|CA175_HUMAN Uncharacterized protein C1orf175 OS=Homo sapiens GN=C1orf175 PE=2 SV=4  ali   9  1...................................................................................................................................................KNMDGMLVVEAVHNLKADSAVYVEMLQILLPHFSDAREVVCINLYGKVVQKLRAPRTQAMEEQLVSTLVPLLLTMQEGNSKVSQKCVKTLLRCSYFMAWELPKRAYAKNSRASLRKCSVMFIGSLVPTEDRLNEVKAALDNLRHDPEASVCIYAAQVQDHILASCW... 222
54 -12.200sp|Q8TF05|PP4R1_HUMAN Serine/threonine-protein phosphatase 4 regulatory subunit 1 OS=Homo sapiens GN=PPP4R1 PE=1 SV=1  ali   6  4LSLLQEDLQEDADGFGDDYSSESDVIIIPSALDFVSQDEMLTPLGRLDKYAASENIFNRQMVARSLLDTLREVCDDERDCIAVLLADDSEPTVRAEL--------------------------------------MEQVPHIALFCQENRPSIPYAFSKFLLP------------VVRYLADQNNQVRKTSQAALLALLEQELIERFDVETKVCPVLIELTAPDSNDDVKTEAVAIMCKMAPRLILPRFCEMCCDCRMFHVRKVCAANFGDICGQQATEEMLLPRFFQLCSDNVWGVRKACAECFMAVSC...... 281
55 -12.200sp|Q9P260|K1468_HUMAN LisH domain and HEAT repeat-containing protein KIAA1468 OS=Homo sapiens GN=KIAA1468 PE=1 SV=2  ali   6  149...................................................................................................................................................................................................................AELLPQCWEQINHKYPERRLLVAESCGAL-SSLVLSMLQQMLMEDKADLVREAVIKSLGIIMDDPDKYHQGFELLLSALGDPSERVVSATHQVFLPA........ 256
56 -12.100sp|Q7Z745|HTRB2_HUMAN HEAT repeat-containing protein 7B2 OS=Homo sapiens GN=HEATR7B2 PE=2 SV=3  ali   8  23.........................................................................................................................................................LELLTDRDVSFYFKEIVLQTRTFFEDEQDDVRLTAIFLFEDLAPLTGRRWKIFFAEEIKKSLISFLLHLWDPNPKIGVACRDVLMVLGLQELYGVLDRLLFTSTWEVIRSAAVKLTDAVVLNLTSQEQLTTRLQALRQDPCISVQRAAEAALQTLLRETSIP. 234
57 -12.100sp|O75155|CAND2_HUMAN Cullin-associated NEDD8-dissociated protein 2 OS=Homo sapiens GN=CAND2 PE=1 SV=3  ali   11  35...................................................................................................................................................................................................................EDIWALLFQRCEGAEEGTRGVVAECIGKLVLVNPSFLLPRLQLAAGRPHTRSTVITAVKFLISDQPHPKSFIGEFMESLQDPDLNVRRATLAFFNSA........ 138
58 -12.100sp|A2RTY3|CQ066_HUMAN Uncharacterized protein C17orf66 OS=Homo sapiens GN=C17orf66 PE=2 SV=2  ali follow..  7  149.............RLRELTKSLES-----------PREDEQFYAAQALGCLRISDKFVMEALQQVAQTGPEGCLNKHVIRALIKQLKEKNEGQRMETLTGLRMALNSWAAVSKDKEGKLVPVLQTLIKKSSSEASLEAALCLGFLRPCSNMV-QEFLLQCLCQGLKTQRMKALRMLVKVMHVHSAPVIKAILD--------------------------QLCSSSVLEDRFEATQMLKTIGLELTFNLLRRKTHNEPFLAVRQAVAQTVEELK----LKPTMMNLVEAQLMNPDATARQEAVISLGVLGIRSP... 434
59 -12.000sp|Q86VP6|CAND1_HUMAN Cullin-associated NEDD8-dissociated protein 1 OS=Homo sapiens GN=CAND1 PE=1 SV=2  ali   13  30...................................................................................................................................................................................................................ENIWALLLKHCECAEEGTRNVVAECLGKLTLIDPETLLPRLYLISGSSYARSSVVTAVKFTISDHPQPKNCIGDFLKTLEDPDLNVRRVALVTFNSA........ 133
60 -12.000sp|Q86VP6|CAND1_HUMAN Cullin-associated NEDD8-dissociated protein 1 OS=Homo sapiens GN=CAND1 PE=1 SV=2  ali   9  8FFQALVVTGTNNLGYMDLLRMLTGPV--YSQSTALTHKQSYYSIAKCVAALTRAPKEGPAVVGQFIQDVKNSRSTDSIRLLALLS--------------------------------------LGEVGHHIDLSGQLELKSVILEAFSSPSEEVKSAASYALGSISVGNLPEYLPFVLQEITSQPKRQYLLLHSLKEIISSASVVGLKPYVENIWALLLKHCECAEEGTRNVVAECLGKLTLIDPETLLPRLYLISGSSYARSSVVTAVKFTISDHPQPKNCIGDFLKTLEDPDLNVRRVALVTFNSAAHNKPLP. 300
61 -11.900sp|Q29RF7|PDS5A_HUMAN Sister chromatid cohesion protein PDS5 homolog A OS=Homo sapiens GN=PDS5A PE=1 SV=1  ali   8  5............FELEDCNEIFIQLFRTLFSVINNSHNKKVQMMLDLMSSIIMEGD-LLDSILINLIPAHKNLNKQSFDLAKVLLKRTVQ-CIANFFNQVLVLGRSSVSDLSEHVFD--------------LIQELFAIDPHLLLSV------MPQLEFKLKSNDGEERLAVVRLLAKLFGSKDSDLA--------------------TQNRPLWQCFLGRFNDIHVPVRLESVKFASHCHPDLAKDLTEYLKSHDPEEAIRHDVIVTIITAAKRALVNDQLLGFVRERTLDKRWRVRKEAMMGLAQL........ 275
62 -11.900sp|Q9P260|K1468_HUMAN LisH domain and HEAT repeat-containing protein KIAA1468 OS=Homo sapiens GN=KIAA1468 PE=1 SV=2  ali   9  179....................................................................................................................................................................................................................GFLEDVMTLLSLSHAPLDSLKASFVELGANPAYHELLLTVGVVHTSALVRCTAARMFELTLSEALVDKRVAPALVTLSSDPEFSVRIATIPAFGTI........ 280
63 -11.800sp|Q5VYK3|ECM29_HUMAN Proteasome-associated protein ECM29 homolog OS=Homo sapiens GN=ECM29 PE=1 SV=2  ali   12  92...................................................................................................................................................................................................................VDKTEWIKSLMNNSKEEMRELAALFYSVVVSTSMIEQLIKTTKDNHSPEIQHGSLLALGFTVGRYLAKQSATETIGSFLDSTSPLLAIAACTALGEIGRNGPLP. 227
64 -11.700sp|O75533|SF3B1_HUMAN Splicing factor 3B subunit 1 OS=Homo sapiens GN=SF3B1 PE=1 SV=3  ali   10  191...................................................................................................................................................................................................................HDVLATLLNNLKVQERQNRVCTTVAIAIVAETCSPFTVLPAEYRVPELNVQNGVLKSLSFLFEYIGEMYAVTPLLEDALMDRDLVHRQTASAVVQHM........ 295
65 -11.700sp|Q9NTI5|PDS5B_HUMAN Sister chromatid cohesion protein PDS5 homolog B OS=Homo sapiens GN=PDS5B PE=1 SV=1  ali   4  19..........................................................................................................................................................................................................................LGRFNDIHVPIRLECVKFASHCNHPDLAKDLTEYLSHDPEEAIRHDVIVSIVTAKDILLVNDHLLNFVRERTLDKRWRVRKEAMMGLAQI........ 115
66 -11.500sp|Q92616|GCN1L_HUMAN Translational activator GCN1 OS=Homo sapiens GN=GCN1L1 PE=1 SV=6  ali   10  18............................................................................................................................................................................................................KVDAVIRKNIVSLLLSMLGHDEDNTRISSAGCLGELTEEELSAVLQQCDVSGIDWMVRHGRSLALSVAVNVAPGRSDVQEMILSSATADRIPIAVSGVRGMGFL........ 135
67 -11.500sp|O75533|SF3B1_HUMAN Splicing factor 3B subunit 1 OS=Homo sapiens GN=SF3B1 PE=1 SV=3  ali   9  1..............................................................................................................................................................................................................SAREWMRICFELLELLKAHKKAIRRATVNTFGYIAKAIGPHDVLATNLKVQERQNRVCTTVAIAIVAETCS-PFTVLPALMNEYRVPELNVQNGVLKSLSFL........ 104
68 -11.500sp|Q6KC79|NIPBL_HUMAN Nipped-B-like protein OS=Homo sapiens GN=NIPBL PE=1 SV=2  ali   11  7...............................................................................................................................................................................................................................................LARLDMQRGVHGRL-MDNSTSVREAAVELLGRVLCRPQLAEQYYDMLIERILDTGISVRKRVIKILRDI........ 75
69 -11.500sp|Q86WZ0|HEAT4_HUMAN HEAT repeat-containing protein 4 OS=Homo sapiens GN=HEATR4 PE=1 SV=1  ali   8  1.....................................................................................................................................................................................................................................................TDLLLWAIHYEESPGVRLEACRSILALK---QGDRVRDTFLDVLLLENHDAVLKEMYQTMKILN....... 62
70 -11.400sp|A6NGR9|CH073_HUMAN Putative uncharacterized protein C8orf73 OS=Homo sapiens GN=C8orf73 PE=2 SV=2  ali   8  40..................................................................................................................................................LDDTRDSIRASAVGLLGTRGGLRLGLRGPLRKLVLQSLVPLLLRLHDPSRDAAESSEWTLARCDHAGLLEELVTVAHYDSPEALSHLCCRLVQRYPGHVPNFLSQTQLRSPQDPLRRAAAVLIGFLVHNQDLLDSLFQDLGRLQSDPKPAVAAAAHVSAQQVAMLAR... 223
71 -11.400sp|P42345|MTOR_HUMAN Serine/threonine-protein kinase mTOR OS=Homo sapiens GN=MTOR PE=1 SV=1  ali   13  3.....................................................................................................................................................................................................................VRHCADHFLNSEHKEIRMEAARTCSRLLTPDVLSKLLVVGITDPDPDIRYCVLASLDERFDAHLAQAENLQALFVALNDQVFEIRELAICTVGRLSSMNP... 123
72 -11.400sp|Q9NTI5|PDS5B_HUMAN Sister chromatid cohesion protein PDS5 homolog B OS=Homo sapiens GN=PDS5B PE=1 SV=1  ali   7  1...............NEIFTQLYRTLF--SVINNGHNQKVHMHMVDLMSSIICEGDTVSQELLDTVLVNLVPAHKNL---------NKQAYDLAKALLKRTAQAIEPYITNF-------FNQVLMLGKTSISDLSEHVFDLILELYNIDSHL-LPQLEFKLKSNDNEERLQVVKLLAKMFGAKDSELA--------------------SQNKPLWQCYLGRFNDIHVPIRLECVKFASHCHPDLAKDLTEYLKSHDPEEAIRHDVIVSIVTAAKKLLVNDHLLNFVRERTLDKRWRVRKEAMMGLAQI........ 265
73 -11.400sp|Q15021|CND1_HUMAN Condensin complex subunit 1 OS=Homo sapiens GN=NCAPD2 PE=1 SV=3  ali   7  3..................................................................................................................................................................................................................................................DSQLRLLFTMLEKSPLPIVRSNLMVATGDL---PNLVDPWTPHLYARLRDPAQQVRKTAGLVMTHL........ 69
74 -11.400sp|P30153|2AAA_HUMAN Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform OS=Homo sapiens GN=PPP2R1A PE=1 SV=4  ali follow..  9  309FCENLSADCRENVIMSQILPCIKELVSDANQHVKSALASVIMGLSPILGKDNTIEHLL-PLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSL----MAWLVDHVYAIREAATSNLK-----------KLVEKFGKEWAHATI-------------------------IPKVLAMSGDPNYLHRMTTLFCINVLSEKHMLPTVLRMA-GDPVANVRFNVAKSLQKIGDNSTLQSEVKPILEKLTQDQDVDVKYFAQEALTVLS....... 587
75 -11.300sp|P30154|2AAB_HUMAN Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform OS=Homo sapiens GN=PPP2R1B PE=1 SV=3  ali   11  171..............................................................................................................................................................................................................SNAVKAEIRQQFRSLCSDDTPMVRRAAASKLGEFAKSEIVPLFTSLA-SDEQDSVRLLAVEACVSIASQDDLETLVMPTLRQAAEDKSWRVRYMVADRFSEL........ 282
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Pawlowski K, Pio F, Chu Z, Reed JC, Godzik A. PAAD - a new protein domain associated with apoptosis, cancer and autoimmune diseases. Trends Biochem Sci. 2001 Feb;26(2):85-7.