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Query: IDP04225 gene: ipaB; IpaB, secreted by the Mxi-Spa secretion machinery, required for entry into epithelial cells [Shigella flexneri] CAC05803 [Shigella flexneri], from CSGID

Results of FFAS03 search in NEW_HUMAN_DOMAINS
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MHNVSTTTTGFPLAKILTSTELGDNTIQAANDAANKLFSLTIADLTANQNINTTNAHSTSNILIPELKAPKSLNASSQLTLLIGNLIQILGEKSLTALTNKITAWKSQQQARQQKNLEFSDKINTLLSETEGLTRDYEKQINKLKNADSKIKDLENKINQIQTRLSELDPESPEKKKLSREEIQLTIKKDAAVKDRTLIEQKTLSIHSKLTDKSMQLEKEIDSFSAFSNTASAEQLSTQQKSLTGLASVTQLMATFIQLVGKNNEESLKNDLALFQSLQESRKTEMERKSDEYAAEVRKAEELNRVMGCVGKILGALLTIVSVVAAAFSGGASLALAAVGLALMVTDAIVQAATGNSFMEQALNPIMKAVIEPLIKLLSDAFTKMLEGLGVDSKKAKMIGSILGAIAGALVLVAAVVLVATVGKQAAAKLAENIGKIIGKTLTDLIPKFLKNFSSQLDDLITNAVARLNKFLGAAGDEVISKQIISTHLNQAVLLGESVNSATQAGGSVASAVFQNSASTNLADLTLSKYQVEQLSKYISEAIEKFGQLQEVIADLLASMSNSQANRTDVAKAILQQTTALast
1 -5.080sp|Q9NSG2|CA112_HUMAN Uncharacterized protein C1orf112 OS=Homo sapiens GN=C1orf112 PE=1 SV=1  ali   9  2........................................................................................FLPHMNHLTLEQTFQVLPKTVKLFDDMMYELTSQARGLSSQNLEIQTTLRNILQTMVQLLGALTGCVQHICATQESII--------QSLPSSVLHIIKSTFVHCKNSESVYSGCLHLVSDLLQALFKEAYSLQKQLMELLDMVCMDPLVDDNDDILNMVIVIHSLLDICSVISSMDHAFHANTWKFIIKQSLKHQSIIKSQAEQMTQSDAQDNADYRLFQKTLKLCRFFANSLLHYAKEFLPFLSDSCCTL-LYLQIHSKFPPSLYATRISKAHQEEIAGAFLVTLDPLISQLFMQVVLDSKLDLPCELQFPQCLLLVVVMDKLPSQPKEVQTLWCTDSQVSETTTRISLLKAVFYSFEQC--TLYQHVCVHLCTFITSFHPSLFAELDAALLNAVLSANMITSLLAMDAWCFLARYGTAELCAHHVTIVAHLIKSCPGECYQLINLSILLKRLFFFMAPPHQ--LEFIQKFSPKEAENLPLWQHI...... 534
2 -5.070sp|Q5T1A1|DCST2_HUMAN DC-STAMP domain-containing protein 2 OS=Homo sapiens GN=DCST2 PE=2 SV=2  ali   10  1...............................................................................................................................................................................................................................................................................................................SRQVRAT---------VLLLLPQAFSRQGRTLLLVAAFGLVLQGPCANTLRNFTRASEAVACGAENQTAEVLQRAKQPLVSALNKI---KAIARKTKEVADRVRKFFRSIMDGVKHIARALRNVWQWLLHIGDVCNSELGNPYLKCARVFDDAKDSCMMVI.................................................................................................................... 152
3 -4.820sp|Q96Q15|SMG1_HUMAN Serine/threonine-protein kinase SMG1 OS=Homo sapiens GN=SMG1 PE=1 SV=3  ali   8  2................................................................................................TLQHRYSEHTQLQTQQRAVQEAIQVKLNEFEQWITHYQAAFNNLEA-------------TQLASLLQEISTQMDLGPPSYVPATAFLQNAGQ-AHLISQCEQLEGEVGALLQQRRSVLRGCLEQLHHYATVALQYPKAIFQKHR-CNTTVERCQELYRKYEMQYAPQPPPTVCQFITATEMTLQRYAADINSRLIRQVERLKQEDQLKEIERCIKVFLEGSLSLASVIISALCTLTRRNLMMEGAASSAGEQLVDLTSGAWFLEELC--SMSGNVTCLVQLLKQCHLVP------QDLDIPNPMEASETV------------------HLANGVYTSLQELNSNFRQIIFPEALRCLMKG-EYTLESMLHELDGLIEQTTDGVPLQTLVESLQAYLRNAAMGLEEETHAHYIDVARLLHAQYGELIQPRNGSVDETPKMSALLVAFDGMFAQVETAFSLLVEKLNKMEIPIAWRKIDIIREARS 473
4 -4.520sp|Q6ZRQ5|MMS22_HUMAN Protein MMS22-like OS=Homo sapiens GN=MMS22L PE=1 SV=3  ali   10  145................................................................................................................................................................................................................................................KQLVKLTRLLFNLSEVKSIFSKAQVEYLSISEDPKKALVR---EAVGVTYGNVQTLSDKSAMVTKSLEYLGEVLKYIKPYLG--KKVFSAGLQLTYGMMGILVKSWAQIFATSKAQKLLFRIIDCLLAPMLSAIQKSLPLYLQGMCIVCCQSQNPNAYLNQLLGNVIEQVLLALRNTATIPPISSLKKCIVQVIRKSYLEYKGSSPPPRLASILAFILQLFKET-NTDIYEVELLLPGILKCLVLVSEPQVKRLATENLQYMVKACQVGSEEEPSSQLTSVFRQFTVATLDQQVVIHLISTLTQSLKDSEQAQREAYSKLLSHLGQMGQDEMQRLENDNT 537
5 -4.140sp|Q2PPJ7|RGPA2_HUMAN Ral GTPase-activating protein subunit alpha-2 OS=Homo sapiens GN=RALGAPA2 PE=1 SV=2  ali   10  10....................................................................................................................................................................................................................................................HPDSAAVLWRRVLGILGDNNIQSPKIHARVFCYLYELWYKLAKIRDNLAISLDNQSSPSPPVLIPPLRMFASWLFKAATLPNEYKEGKLQAYRLI--------AMMTRRQDVLPNSDFLVHFYLVMHLGLTSEDQDILNTIIRHCPFFSLGFPGFSMLVGDFITAAARVLSTDILTAPRSEAVTVLGSLVC--FPNTYQEIPLLQSVPEVNEAITGTEDVKHYLINILLKNATEEPNEYARCIAVCSLGVWICEELAQCTSHPQVKEAINVIGVTLKFPNKIVAQVACDVLQLLVSYWEKLQMFETSLPRKMAEILVATVAFLLPS.......... 329
6 -4.090sp|Q562E7|WDR81_HUMAN WD repeat-containing protein 81 OS=Homo sapiens GN=WDR81 PE=2 SV=1  ali   9  1.....................................................................................................................................................................................................................................................................................................KEQKILLDTACKMVRWLSAKLGPTVASLRLLTSCYVGPTRQQVLGDIVSGPVLSCLLHIARGEPVLTYQYLPYISYLVAPGSATLTQKIIVYLSDTTLMDILPRISHEVLLPVLSFLTSLSGAQARTILCVKTISLIALICLRIGQEMVQQHLSEPVATFFQVFSQL........................................................................................................................ 220
7 -4.030sp|Q8WTW3|COG1_HUMAN Conserved oligomeric Golgi complex subunit 1 OS=Homo sapiens GN=COG1 PE=1 SV=1  ali   11  19...........................................................................................................................................................................................................................................................ILHESKMLLKCQGVSDQAVAEALCSSPRQALTDFLLARKATIQKLLNQPHHGAGIKAQICSLVELLATTLKQAHALFYTLPEGLLPDPALPCGLLFSTLETITGQPISQEYLKDTLQKWIHMCNEDIKNGITNLLMYV----KSMKGLAGIRDAMWELLTNESTNHSWDVLCRRLLEKPLLFWEDMMQQLFLDRLQTLTKEGFDSISSSS....................................................................................................................... 270
8 -3.990sp|O94822|LTN1_HUMAN E3 ubiquitin-protein ligase listerin OS=Homo sapiens GN=LTN1 PE=1 SV=6  ali   9  29...........................................................................................................................................................................................................................................................HLRFLSTLLDSFSSSRV---KMLLGDEKQSIVQAKPLEIAKLVQKNPAVQFLYQKL--FGFLVDILYSALRCCDN--DMERKKVLDDL-SLLKIIEKACPSSDKHALVTPWLK--GDILGEKLVNLADCLCNEDLESRVSSESHFSERWTLLSLVLSQHVK---------IGDVYVERIIVRLHETLFKTKKLSEAESSDSSVSFICDVAYNYFSSAKGCLLMPSSEDLLLTLFQLCAQSKEKTHLPDFLICKLKNTWLSGV--NLLVHQTDSSYKESTFLHLSALWLKNQVQASSLDINSLQVLLSAVDDLLNTLLESE......... 351
9 -3.890sp|O43156|TTI1_HUMAN TEL2-interacting protein 1 homolog OS=Homo sapiens GN=TTI1 PE=1 SV=3  ali   11  9..............................................................................................................................................................................................................................................KTPGPKRERLIQSVVECLTFVLSSTCVKEQELLQELFSELSACLYSPSSQKPAAVSEELKLA-----VIQGLSTLMHSAYG--DIILTFYEPSILPRLGFAVSLLL---GLAEQEKSKQIKIAALK-----CLQVLLLQCDCQDHPRSLDELEQKQLGDLFASFLPGISTALTRLITG------DFKQGHSIVVSSLKIFYKTVSFIM...................................................................................................................................... 195
10 -3.880sp|A6NCN8|YL021_HUMAN Uncharacterized protein ENSP00000372125 OS=Homo sapiens PE=4 SV=2  ali   12  2...................................................................................................................................................................................................................................................................MGQNSFLTFIHCYPTFVDMKRKKQFRTVKELKEVEKLKLRSEARAPPLDAQGNIQ.......................................................................................................................................................................................................................................................................... 58
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 2 6 8   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Friedberg I, Godzik A. Fragnostic: walking through protein structure space. Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W249-51.