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Query: IDP92583 beta adaptin protein, putative [Toxoplasma gondii ME49] TGME49_040870 [Toxoplasma gondii ME49], from CSGID

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MTDGNYFQPAKRGELHELKEELHSSNKEKKKEAVKKVIAAMTVGKDVSSLFPDVVNCMQTTNMELKKLVYLYVINYAKAQPELAILAINTFRKDSLDPNPLIRALAVRTMGCIRLEEITEYLVEPLRRSCKDPDPYVRKTAAICVAKLFSIRPDMVGEEGFIEELTTMLSDSNPVVVANAVAALSEISENSGRNYMKNILNAKESNVNKLLAALNECTEWGQVFILDALAQFEPETPRAAESVLDRVTARLSHANSAVVLSAIKVVMKLLDKVTNPDVVRAVHRKLCPPLVTLLSAEPEIQYVALRNIELIVQKRPSILASEVKMFFCKYNDPVYVKIEKLDILVRLVSEKNVDQVLSELKEYATEVDVDFVRKAVRCIGRCAIKLDCAAERCVAVLLDLIQTKVNYVVQEAIVAIKDIFRKYPNQYESMISTLCENLETLDEPAAKASMVWIVGEYVDRIDNADELLETFLETFHDEPSIVQLQLLTATVKLFLKKPAHTQDLVTKVLKMATEETYNPDLRDRAYIYWRMLARNPEAAKKVVFAPKPPINEDADALDYNTLDRLIGNISLLSSVYHKAPETFVARAMPPSAALPKEVGSCSSDGESTDARVEQAKQSMQKQHYSSDEKEEESSPTSSEDSDSDSDGPTDLLGLSDEATPRKRSSKESSDDLFDLSSPPEDPRGVGKTLVLAADRPGNQGRTGLQVSAALTRAHGRIQLHLTLANKSSMTLNGWAIQFNRNSFGLAPAANLQVADLLSGQSAETTVPVVPGQLMSNAAPEQPLSLQVAVKTNLDIFCFTVPFDLSVVLQENSSADKDVFRQRWQNIGEARQSSLMASAPSSQSPQAVTKQMQAANISLVAQRSADTFDALYFSATTTNNLVVLAEVSLQRNGNAVKLVTRSEAAALLPLFTSTVCAALRLTPRSLast
1 -90.500PF01602.20; Q22601_CAEEL/28-590; Adaptin N terminal region  ali follow..  19  2.......LKRINKELANIRSKFKGDDGYQKKKYVCKLLFIFLLGNDIDFGHMEAVNLLSSNKYTEKQIGYLFISVLIEQQSDLMKLIVQGIRNDLTSRNPVHVNLALQCISNMGSREMVEAFCTDLPKLLGETIDFVKQSAALCILKLFRNSPDSFQPGDYASRIVHLLNDSHMGVVTSAASLIEALSKKWPEEYKGAVPLAIS-TDLQDYTYYFVPAPWLCVKLLRLLQNYPPPDDPSNKARLKAQDAPKSKKVQHSNAKNAVLFEAIALIIHMDSEPQLLVRACNQLGTFLSHRETNLRYLALESMCLLATSEFSHDAQDTIINSLKTERDVSVRQRAVDLLYAMCDRSNANQIVAEMLAYLETADYSIREEMVLKVAILAEKYATDYTWYVDVILKLIRIAGDYVSEEVWYRVIQIVVNREDVQGYAAKTVFEALQRPACHEMVKVGGYILGEFGNFIAGDEIQFELLHSKFHLCSITTRCLLLTTYIKFCNLFPEIKPLVQQVFQTDHNLRNPDAELQQRSIEYLQMTKLAS.................................................................................................................................................................................................................................................................................................................................................................................................... 563
2 -42.400PF12717.7; G8Y240_PICSO/105-271; non-SMC mitotic condensation complex subunit 1  ali follow..  47  1....................................................................................................LIRALAIRTMGCVRVARMVDFIEIPLKRTLSDDNPYVRKTAAICVAKLFDLSPKACVEFGFLDQLRGLIKDSNPMVVANALNSLFEIKDMNVDSSLV-VLEFDSELIKTLLMCLNECTEWGRITILDTLTKYEASSSEEASHIIDRATPQLQHANPSVVLSSIKVILH................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 167
3 -23.100PF09066.10; A0A068XBU3_HYMMI/884-992; Beta2-adaptin appendage, C-terminal sub-domain  ali follow..  25  1........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................TSAGEMEKMVFLATWKDIPPENEQQFVLS-PLTLDADTCSQKLRSNNIFTIAQRNVDGQDMLYQSMKLCNGIWVLAELKIQPGNMSYTLSLKSRAMDVHPYVREAFHGIL...... 109
4 -18.300PF10508.9; A7SP09_NEMVE/2-505; Proteasome non-ATPase 26S subunit  ali follow..  9  7....................................................ELVENISNASGDEIVAFLRDLSVLISSSPNIRDLASERLFNCLRTTNTDQITYCKNILKNIKPDAPATKYHDAVIEGLNHPTEDVRELCLIELERCSGTVNGLMDKEDLLSYIARGMADEHLKNAQIASNVFTNLAKHE-----AGLKVLFDSHLQSEFNALLKTKDTVRMRVYDMYITVQAHSPKAFDVIFEKLISELDGRDVLVQMNCLELLTKLASISPSGLEYLDQKGVVTKLNNLLLEVETDIIPGIIKFFGTLATAHPLETTQQYPQFLMISCGDPTLMPIAMETIGVIAHSEDNKHIMKTIFGHATSSQVDLRKRALEALASIFYSEQLTPS---EELCEFAKVLYKNMAAAPLEAIFTVAKQFEELRCSALCLLRSLARY------------------QDMINCPGFLEYLLDRRTEFEKSGKEHKYDLIKEL............................................................................................................................................................................................................................................................................................................................................................................................................................................... 463
5 -15.500PF02296.16; A7RH33_NEMVE/829-938; Alpha adaptin AP2, C-terminal domain  ali follow..  8  1.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................FFTSVEMNSQDFFTRWKGLSSPQECQKIFQAKYPMESGTIATKLSGFGLAIQ-NGVDPNPENFVCAGIIAGQVGCLLRLEPNRQAKMYRLTLRSSRPEVATHLCEL........... 110
6 -14.600PF05918.11; D7TJH2_VITVI/11-547; Apoptosis inhibitory protein 5 (API5)  ali follow..  12  2............EKLYEYGERLNEKDKSQNVEDYRGII-------------------AAKGSIKAKQLAAQLIPRFFKFFPDLSDAAVDSHLDLCEEEELGVRVQAIRGLPLFDTPEYVSKIVDILAQLLTAEENVERDAVHKALLSLLRQDVKASLTGLFKHIMTVDDPSTDENLREKVLNFIRDKVFPLKAELLKPQEQMERHITNLIKKSLEDVTGAEFKMFMDFLRSLTLFGEKAPPERVQELIEIIEGQADLDA----------QFNVSDGDHIDRLISCLYMALPFFVRGASNSKFL------------------------------NYLNKHIIPVFDKLPEERKLD-LLKNLAESSPYSAPQDSRQILPSVVQLLKKYMPRRKTGEETNFTYVEC--------LLYTFHHLAYKAPNATNSLCGYKIVTGQPSD----------------RLGEDFSEYYKDFTE---------RLTHVEELARATMKKLTQGMAEHNKAMAAAKSDEAKDNIKTQKQNTTTGLRTNILAMTQPLHSKSPSFIGDKRINLSWKEATKPSVPSTAMAAGGKRPASTTNGASNAAAKKGRGAGGLQNQLVNRALEGLSHGGRSGIR.............................................................................................................................................................................................................................................................................................................. 524
7 -13.900PF05804.12; KIFA3_HUMAN/13-720; Kinesin-associated protein (KAP)  ali follow..  12  119.............NINDMDEYIEYEDIPDKVRGSALILQLLLLNETALGALARVLREDWKQSVELATNIIYIFFCFSSFHYKIGALCMNIIDHELVVKQEQLLRVALYLLLNLAEDTRTELIVHMLVKALDRDNFELLILVVSFLKKLFMENKNDMVEMDIVEKLVKMIPCEHEDLLNITLRLLLNLSFDTGLRNK-----VQVGLLPKLTALLGNDN--YKQIAMCVLYHISMDDRFKSTDCIPQLMKMLFECSDERIDLELISFCINLAANKRNVQLICEGNGLKMLMKRALKFKDPLLMKMIRNISQHDGPTKNLFIDYVGDLAISNDEEEEFVIECLGTLANLTPDLDWELVLKELKDKLKAAEDDLVLEVVIMIGTVSMDDSCAAL-IIPALIELLNAEDDEFVCQIIYVFYQMVFHQATKETQAPAYLIDLMHD-KNNEIRKVCDNTLDIIAEYDEEWAKKIQS...................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 661
8 -13.000PF14631.6; U3I414_ANAPL/1-1417; Fanconi anaemia protein FancD2 nuclease  ali follow..  9  19.PDLPSRCSETKKPRASDKEKASAQGGLESEGVFEELLR-NEIAVDQMAFQKKLRLTLEKHPTYPGVVKQFILESHIRDRNQFKNCLLPCAPVRTEGSRTLVHSYCIKMLLGINIPAVITLLLEKIPEFFFDVVGTFGTNFPRLIVNQFKWLDGLLDSQDLVKKLMQMLSVSPVPIQHDIITSLPEILEDSQSEVARELGCLLKE------------GRRLTVPILDALSRLD--DAELLAEVQQSAMTIVPSVKLEDLPVVVKFILHNVKAANAVEVISDLRKNLDSSSTSQVTTSQNCVKLLFDVIKLAVRFQKDVSEAWIKAIENTTSVSDHKKVLDLIVLLLIHSTNTKNRKQAEKVLRSKIRLGCMPEQLMQNA---FQDHSMVIRDFFPSILVFLHAAHPAIVSFGSCMYKQAFAVFDSYQQEVVSALVTHVNEAELDIALDVLTDLVVVHTSLLMRYATFVKTILDSTQKLNPCQIRKLFYILSTLAFSQRQEGSYIQDDMHMVIRKWLSSTVPNHKQMGIIGAVT....................................................................................................................................................................................................................................................................................................................................................................................................... 584
9 -13.000PF14796.6; K7IWJ5_NASVI/813-956; Clathrin-adaptor complex-3 beta-1 subunit C-terminal  ali follow..  13  20...............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................MTPSLGGFLTPIMPSPAFATASDGIREVSTSFIPVKKYELLNKVSGRGLKLEYRFTRSPALVNIELTFANEGTETIKDIRVGNKNLATGMSLHDFSPIPVLQPNSSLACTIGINFNDSTQ..................................................................................................................................................... 144
10 -12.700PF14228.6; F6GVU1_VITVI/618-1735; Cell morphogenesis central region  ali follow..  9  122..............VRYAAELCPSSVQEAKLEVIQRLAHITPA---------KAHQSQDTDNKLDQWLMYAMFACSCPFDSDLYHLIFPSLKSGSEAHIHAAT-MALGHSHLEVCEIMFGELASFIDEVSMETEG--ARREEL-IANIYRTVSENIWPGKFIEETTRQILTAPQPLRYALASVLRSLAPEFVDSKSEKFDLRTRKRLFDLL------LSWASMNAMASLLCFDDNARKMSGRVISWINSLFNEPAPRAPFGYSPADPRTPSYSKYTGE-----GPRGAAGRDRHRGGHLRVSLAKMALKNLLLTNLDLFPACIDQCY---YSDAAIADGYFSVLAEVYMRQEIQRLLSLILYKVVDPNRQIRDDALQMLETLSVREAEDGGEGSGSYRAAVVGNLPDSYQQFQYKLCKLAKDHPELSQLLCEEIMQRQLDAVDIIAQHQVLWI------------------LNFWKLKDSGWSERLLKSLYYVTWRHGDQFPDEIEKLWSTIASKPRNISP................................................................................................................................................................................................................................................................................................................................................................................................................... 698
11 -12.600PF17741.1; A0A151PBS4_ALLMI/1-268; Family of unknown function (DUF5578 topsan)  ali follow..  12  2.........................................................................................................................................................TSAKEQAAIGRLLAFLQEWDNAGRAARSRILDNFIEANQGKMGPELELEFSQGAS------------FLARLTAWLRLSNGTCLDQLLKAIGIFLSAASGHRYLIEFLEVGGVLTLLEILGLSQLKEEDKKESIKLLQLVANAGRKYKELICESVRSIAE-------------FMASSKSEKAQRQVQILLDSLGNPKYQNQVYKGLIALLPCTSPHAQQLSLQTLRVVQAIVGKSHPSIVEAVLGVLRSMELEVQYEAIQLIKDLTSY--DVRPALLRGLVALLK..................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 267
12 -12.100PF13646.6; C3YB05_BRAFL/324-412; HEAT repeats  ali follow..  26  1.......................................................................................VSSLKKLLVDEDPNIRAVASIALGKTGTCT--PDIVEALVNLLKDEDRLVRESTCVSLGYL--------AQDAVPHVINAWRNDPISHVREAAQAAL.................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 88
13 -10.600PF12348.8; B8M2E9_TALSN/325-551; CLASP N terminal  ali follow..  13  1..........IDDMLRNMLPHFTEHNWIPREKSVETLRRLVRGN--IKSLLDGILKVVNSLRTTLSTTGCLLIQEIAKV-DNMVEILLQNMIKLCAGMKKISAQNANATVDAISNVTYVPRILQHLSFACQDKNVQPRLFAAGWLKTLLNKQARHKSSDLVEKCIKKCLGDPNPGVRESMRGTFWTFYKIWPDRAEEIISTLDAKSKTLL.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 226
14 -10.600PF12755.7; C4QYN7_KOMPG/59-156; Vacuolar 14 Fab1-binding region  ali follow..  15  3......................................................................................................RNGGLIGLAATAVPKYLEKIIHPVLACFGDQDARVRYYACESLYNISKVAKGEILLNEIFDNLCKLTADSEVSVKKGA-DLLDRLIKD.............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................. 98
15 -10.500PF14807.6; H2LLU4_ORYLA/1029-1130; Adaptin AP4 complex epsilon appendage platform  ali follow..  9  1..........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................PLTVSTEEYGSMWLAFSHDTKQNLTLIKEEREPLTATLNALKKLSLHVVEIIGVE----GLVACSLLQDQPCLMHCRVHAG--RLAVWLRSPVADLPDCLLYHCQRA....... 102
16 -9.940PF04931.13; K2SXE2_MACPH/89-879; DNA polymerase phi  ali follow..  8  1...............................KAIVRLI----RG-------------LNSGR-KAARFGFVALTETLRQLYGSSSKLVKLVAELTTPEGKVFGYKAIIQSSILVQPNAPEECWANVLEQLAREKPWLREECGMILCEAVKAIAQEKGQQRLVKQIVDGLCSDGLAKTPEGVSVWITVQREIPDMELPQGV-LSTKDRQTLANVMKENFT----VVISAFFQRHGDDPSRFANFWADIVDFSASSSPEQKSKGLQLFTRMLGNAPKWALPSIFSPNMRCLINQRNDSERFLHNAAKAPLDEMRTRSKKEPETAAPFLENLITKDQITKNKTVEGVLGHANDVALEQIVPLFKRLIYRPEEQVADMVVSAVRSRNKENAIGNDSWLREVLVGLEASRNMFQGRLTSCLAHLLSSKLDTEMDYPYIVVSAIRSKSKSSKSLSLV-ADKGISKAVKQAHKQVEEITEKLLKAKDKKKPALFSLTIVQVYNGDPDAVSILEELAVCYESAFQKGALTE---VLLSFAAKPSVLFRKLS---EQVFTVFASELTAEGLHSMIDILSKKESMSGQQDLFDQQGSEDGEDASEDDEDEQDSDVEMVEADGSDVEEVEEASDVDEEEEEDEDEEGGEDGSDADDEELEKFNAALAKTLNTSMLTGEGEDSDD........................................................................................................................................................................................................................................................... 732
17 -9.370PF14961.6; W5NL29_LEPOC/12-1308; Broad-minded protein  ali follow..  11  70.GEGQGVGPGQDTLVHAVTRRTRESNEYKEKNTMMVAVESLINTFEEDKLRKEETHGKSQHEQLSSHYTDNCSDSDCSFNQSYAFIKLQAIAEKIDSSQPKVRWEALQTLCCAPPSDVLTGLRRNLSAALGDPDPAFSDKVLKFYAKTFSSSPLNITREIYTSLAKHLISNQDVARLLKKMRLLNEFQKEVTSFWIRNPEKYMEEIIESTLSLLSLNLD--VLEPIYFLSMLDIKAN-HGYYSRTVVLRLLENKYKSLIVASLQQCINYSSCDKTSNIAHVRQQQQTGTTQRMFYTARQLEYTSVCLLGRLLM-----YTHGRKLF------PIKLKRRK--------DPVTLTDLIVILIRIMYRHPIPYYSSPACLVMDVLRTLCDRKECAVECLYA------IAVIELLLSPIIALLKGKQVNLTSPETTLTHIAD-------------ILARIATTERGLSLFLYDGNFIYTEGEGISAAHVIVQFTKKLLADKTSLKGAFIFVCRQMYNTCEGLGLHDCIAEAWKQTVSLSERVPTPVPGDCSSSATQDSQNNMVWEETLLDNLLNFAAT............................................................................................................................................................................................................................................................................................................................................................. 685
18 -9.280PF04826.13; ARMX3_MOUSE/110-363; Armadillo-like  ali follow..  8  1............................................................................................................................................................................................................................................................SPNSDDTVLSPQELQKVLCLVEMSEKPYILEAALIALGNNAAYAFNRDIIRDLGGLPIVAK--------------ILNTRDPIVKEKALIVLNNLSVNAENQRRLKVDDTVTSRLNSSVQLAGLRLLTNMTVEYQHILANSISDFFRLFSAGNEETKLQVLKLLLNLAENPAMLRAQVPSSLGSLFNKKEYKEVILKLLIIFENINDNFKWEENEP------------AQNHFSEGSLFFFLKEFQVCADKV------LGIESRHDFQVRVKV............................................................................................................................................................................................................................................................................................................................................................................................................... 253
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Ye Y, Jaroszewski L, Li W, Godzik A. A segment alignment approach to protein comparison. Bioinformatics. 2003 Apr 12;19(6):742-9.