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Query: IDP02330 gene: ilvC-1; ketol-acid reductoisomerase [Bacillus anthracis str. `Ames Ancestor`] GBAA1419 [Bacillus anthracis str. `Ames Ancestor`], from CSGID

Results of FFAS03 search in SCOP207
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MAKVYYEKDVTVNVLKEKKVAIIGYGSQGHAHAQNLRDNGFDVVVGLRKGKSWDKAKEDGFSVYTVAEAAKQADVVMILLPDELQPEVYEEEIAPNLQAGNSLVFAHGFNVHFDQVKPPVNVDVFLVAPKGPGHLVRRTFSEGGAVPALFAVYQDATGVATEKALSYADGIGATRAGVLETTFKEETETDLFGEQAVLCGGVTALVKAGFETLVDAGYQPELAYFECLHELKLIVDLMYEGGLENMRYSVSDTAQWGDFVSGPRVVTEDTKKAMGTVLAEIQDGTFARGWIAEHKAGKPNFYATNEKENEHEIEVVGRKLRGMMPFVQPRVKAGVKLast
1 -53.400d4ypoa1 c.2.1.0 (A:1-180) automated matches {Mycobacterium tuberculosis [TaxId: 1773]}  ali model 3D-neighbors follow..  53  1...MFYDDDADLSIIQGRKVGVIGYGSQGHAHSLSLRDSGVQVRVGLKQGSRSRPVEEQGLDVDTPAEVAKWADVVMVLAPDTAQAEIFAGDIEPNLKPGDALFFGHGLNVHFGLIKPPADVAVAMVAPKGPGHLVRRQFVDGKGVPCLVAVEQDPRGDGLALALSYAKAIGGTRAGVIKTT.......................................................................................................................................................... 180
2 -35.300d4ypoa2 a.100.1.0 (A:181-325) automated matches {Mycobacterium tuberculosis [TaxId: 1773]}  ali model 3D-neighbors follow..  60  1......................................................................................................................................................................................FKDETETDLFGEQTVLCGGTEELVKAGFEVMVEAGYPAELAYFEVLHELKLIVDLMYEGGLARMYYSVSDTAEFGGYLSGPRVIDAGTKERMRDILREIQDGSFVHKLVADVEGGNKQLEELRRQNAEHPIEVVGKKLRDLMSWV......... 145
3 -34.700d3fr7a1 c.2.1.0 (A:86-307) automated matches {Oryza sativa [TaxId: 39947]}  ali model 3D-neighbors follow..  32  24RGGRNLFPLLPEAFKGIKQIGVIGWGSQGPAQAQNLRDSLAEAKSDRKGSKSFDEARAAGFTLGDIWETVSGSDLVLLLISDAAQADNY-EKIFSHMKPNSILGLSHGFLLQSAGLDFPKNISVIAVCPKGMGPSVRRLYVQGAGINSSFAVHQDVDGRATDVALGWSVALGSP.................................................................................................................................................................. 216
4 -28.500d4dlla1 c.2.1.0 (A:29-190) automated matches {Polaromonas sp. [TaxId: 296591]}  ali model 3D-neighbors follow..  17  2...............YARKITFLGTGSMGLPMARRLCEAGYALQVWNRTPARAASLAALGATIHQARAAARDADIVVSMLENGAVVQDVLQGVAAAMKPGSLFLDMASIT--------PREARDHAARLGALGIAHLDTPVSGGAEQGTLVIMAGGKPADFERSLPLLKVFGRAT................................................................................................................................................................. 159
5 -27.900d2uyya1 c.2.1.0 (A:262-429) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  17  5...............TDKKIGFLGLGLMGSGIVSNLLKMGHTVTVWNRTAEKCDLFIQEGARLGTPAEVVSTCDITFACVSDPKAAKDLVSGVLQGIRPGKCYVDMSTVD--------ADTVTELAQVIVSRGGRFLEAPVSGNSNDGMLVILAAGDRGLYEDCSSCFQAMGKTSFFLGE............................................................................................................................................................ 168
6 -27.700d3ws7a1 c.2.1.0 (A:1-161) automated matches {Pyrobaculum calidifontis [TaxId: 410359]}  ali model 3D-neighbors follow..  20  1.................MRVGFIGLGIMGGPMATHLLKAGFLAAVYNRTREKTKPFAEAGVYVASPADLAKRVDVVIVMVSDAPDVEQVLSGVVEGARPGLIVVDMSTNS--------PDWARKFAERLAQYGIEFLDAPVTGGAIEGTLTIMVGGKEELFHRLLPIFKAMGRDIVYM.............................................................................................................................................................. 160
7 -27.600d5je8a1 c.2.1.0 (A:1-163) automated matches {Bacillus cereus [TaxId: 226900]}  ali model 3D-neighbors follow..  20  2.................KKIGFIGLGNMGLPMSKNLVKSGYTVYGVDLNKEAEASFEKEGGIIGSISKLAETCDVVFTSLPSPRAVEAVYEGLFENGHSNVVFIDTSTVS--------PQLNKQLEEAAKEKKVDFLAAPVSGGAENRTLTFMVGGSKDVYEKTESIMGVLGANIFHVSE............................................................................................................................................................ 163
8 -27.400d2gf2a1 c.2.1.0 (A:41-201) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  16  1..................PVGFIGLGNMGNPMAKNLMKHGYPLIIYDVFPDACKEFQDAGEQVVSPADVAEKADRIITMLPTSINAIEAYNGILKKVKKGSLLIDSSTID--------PAVSKELAKEVEKMGAVFMDAPVSGGARSGNLTFMVGGVEDEFAAAQELLGCMGSNVVYC.............................................................................................................................................................. 159
9 -27.300d2cvza2 c.2.1.6 (A:2-157) Hydroxyisobutyrate dehydrogenase {Thermus thermophilus [TaxId: 274]}  ali model 3D-neighbors follow..  21  1.................EKVAFIGLGAMGYPMAGHLARRFPTL-VWNRTFEKALRHQEEFGSEAVPLERVAEARVIFTCLPTTREVYEVAEALYPYLREGTYWVDATSGE--------PEASRRLAERLREKGVTYLDAPVSGGAEAGTLTVMLGGPEEAVERVRPFLA....................................................................................................................................................................... 146
10 -27.200d3g0oa1 c.2.1.0 (A:6-169) automated matches {Salmonella typhimurium [TaxId: 602]}  ali model 3D-neighbors follow..  14  1................DFHVGIVGLGSMGMGAARSCLRAGLSTWGADLNPQACANLLAEGACAASAREFAGVVDALVILVVNAAQVRQVLDGVAHLMKPGSAVMVSSTIS--------SADAQEIAAALTALNLNMLDAPVSGGAAQGEMTVMASGSEAAFTRLKPVLDAVASNVYRISD............................................................................................................................................................ 164
11 -24.900d3fr7a2 a.100.1.2 (A:308-580) automated matches {Oryza sativa [TaxId: 39947]}  ali model 3D-neighbors follow..  14  1.....LEQEYKSDIFGERGILLGAVHGIVEALFRRYTEQGMD-------------------EEMAYKNTVEGITGIIS----KTISKKGMLEVYNSLTEEGKKEFNKAYSASFYPC---MDILYECYEDVASGSEIRSVVLAGRRFYEKEGLPAFPMGNIDQ----------TRMWKVGEKVRSTRPENDLGPLHPFTAGVYVALMMAQIEVLRKKGHSYSEIINESVIESDSLNPFMHARGVAFMVDNCSTTARLGSRKWAPRFDYILTQQAFV----TVDKDAPINQ-------------DLISNFMSDPVHGAIEVCAELRPTVD........ 271
12 -23.600d4gwga1 c.2.1.0 (A:1-176) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  16  1...............AQADIALIGLAVMGQNLILNMNDHGFVVCAFNRTVSKVDDFLANEAKAQSLKEMVSKLKRIILLVKAGQAVDDFIEKLVPLLDTGDIIIDGGNSE--------YRDTTRRCRDLKAKGILFVGSGVSGGGARYGPSLMPGGNKEAWPHIKTIFQGIAAKVGT............................................................................................................................................................... 165
13 -23.300d1li4a1 c.2.1.4 (A:190-352) S-adenosylhomocystein hydrolase {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  18  16........RATDVMIAGKVAVVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACQEGNIFVTTTGCI---DIILGRHFEQMKDDAIVCNIGH.................................................................................................................................................................................................................................... 112
14 -21.100d1bg6a2 c.2.1.6 (A:4-187) N-(1-D-carboxylethyl)-L-norvaline dehydrogenase {Arthrobacter, strain 1c [TaxId: 1663]}  ali model 3D-neighbors follow..  25  1................SKTYAVLGLGNGGHAFAAYLALKGQSVLAWDIDAQRIKEIQDRGLLTSDIGLAVKDADVILIVVPAIHH-ASIAANIASYISEGQLIILNPG.................................................................................................................................................................................................................................... 107
15 -19.800d2i76a2 c.2.1.6 (A:2-154) Hypothetical protein TM1727 {Thermotoga maritima [TaxId: 2336]}  ali model 3D-neighbors follow..  14  1..................VLNFVGTGTLTRFFLECLKDRYEIGYILSRSIDRARNLAEVGGKAATLEKHPELNGVVFVIVPDRYIKTVANH-----NLGDAVLVHCSGFL-----------SSEIFKKSGRASIHPNFSFSSLEKALEMKDFGLEGDERGLPIVKKIAEEISGKYFVI.............................................................................................................................................................. 149
16 -19.300d1i36a2 c.2.1.6 (A:1-152) Conserved hypothetical protein MTH1747 {Methanobacterium thermoautotrophicum [TaxId: 145262]}  ali model 3D-neighbors follow..  17  1.................LRVGFIGFGEVAQTLASRLRSRGVEVVTSLEGRSPSTIERARTVGVTTSEEDVYSCPVVISAVTPGVALGAARR----GRHVRGIYVDINNIS--------PETVRMASSLIEKGG--FVDAAIMGSVRRKGADIRIIASGRDAEEFMKL......................................................................................................................................................................... 138
17 -17.400d2f1ka2 c.2.1.6 (A:1-165) Prephenate dehydrogenase TyrA {Synechocystis sp. PCC 6803 [TaxId: 1148]}  ali model 3D-neighbors follow..  14  1.................MKIGVVGLGLIGASLAGDLRRRGHYLIGVSRQQSTCEKAVERQLEAGQDLSLLQTAKIIFLCTPIQLILPTL-EKLIPHLSPTAIVTDVASVKTAIAEPASQLWSGFIGGHPAAQGIDGAEENL--VNAPYVLTPTEYTDPEQLACLRSVLEPLGVKIYLC.............................................................................................................................................................. 165
18 -16.500d1jaya_ c.2.1.6 (A:) Coenzyme F420H2:NADP+ oxidoreductase (FNO) {Archaeoglobus fulgidus [TaxId: 2234]}  ali model 3D-neighbors follow..  20  1.................MRVALLGTGNLGKGLALRLATLGHEIVVGSRREEKAEAKAAESITGMKNEDAAEACDIAVLTIPWEHAIDTA-RDLKNILREKIVV......................................................................................................................................................................................................................................... 94
19 -16.200d1qp8a1 c.2.1.4 (A:83-263) Putative formate dehydrogenase {Pyrobaculum aerophilum [TaxId: 13773]}  ali model 3D-neighbors follow..  18  26MKRGDYGRDVEIPLIQGEKVAVLGLGEIGTRVGKILAALGAQVRGFSRTPK-----EGPWRFTNSLEEALREARAAVCALPNKHTRGLVKYQHLALMAEDAVFVNVGRAEVLDRDGVLRI........................................................................................................................................................................................................................ 141
20 -16.100d1j4aa1 c.2.1.4 (A:104-300) D-lactate dehydrogenase {Lactobacillus helveticus [TaxId: 1587]}  ali model 3D-neighbors follow..  16  41..............VRDQVVGVVGTGHIGQVFMQIMEGFGAKVITY--DIFRNPELEKKGYYVDSLDDLYKQADVISLHVPVPANVHMINDESIAKMKQDVVIVNVSRGPLVDTDAVIRG........................................................................................................................................................................................................................ 145
21 -15.700d2pv7a2 c.2.1.6 (A:92-243) Prephenate dehydrogenase TyrA {Haemophilus influenzae [TaxId: 727]}  ali model 3D-neighbors follow..  20  10.................HKIVIVGYGKLGGLFARYLRASGYPISILDREDWAVAE------------SILANADVVIVSVPINLTLETI-ERLKPYLTENMLLADLTSVKREPLAKMLEVHTGAVLGLHPMFGAD------IASMAKQVVVRCDGRFPERYEWLLEQIQIWGAKIYQT.............................................................................................................................................................. 152
22 -15.400d1txga2 c.2.1.6 (A:1-180) Glycerol-3- phosphate dehydrogenase {Archaeoglobus fulgidus [TaxId: 2234]}  ali model 3D-neighbors follow..  16  1.................MIVSILGAGAMGSALSVPLVDNGNEVRIWGTDTEILKSISAGRFWPEQLEKCLENAEVVLLGVSTDG-VLPVMSRILPYLKDQYIVLISKGLIDFDNSVLTVPEAVWRLKHDLRERTVAITGPAIAREVAKRMPTTVVFSSPSESSANKMKEIFETEYFGVEVTT.......................................................................................................................................................... 180
23 -15.300d1saya1 c.2.1.4 (A:136-303) L-alanine dehydrogenase {Phormidium lapideum [TaxId: 32060]}  ali model 3D-neighbors follow..  19  30..............VKPGKVVILGGGVVGTEAAKMAVGLGAQVQIFDINVERLSYLETLFSNSAEIETAVAEADLLIVLVPGRRAPILVPASLVEQMRTGSVIVDVA..................................................................................................................................................................................................................................... 132
24 -15.200d2rcya1 c.2.1.0 (A:2-156) automated matches {Plasmodium falciparum [TaxId: 36329]}  ali model 3D-neighbors follow..  14  1..............MENIKLGFMGLGQMGSALAHGIANANINLFYYGPSKKNTT-------YMSSNEELARHCDIIVCAVKPDIAGSVL-NNIKPYLSSKLLISICGGLNIGKLEEMVGSENKIVWVMPNTPC-------LVGEGSFI-YCSNKNVNSTDKKYVNDIFNSCG.................................................................................................................................................................... 148
25 -15.200d2naca1 c.2.1.4 (A:148-335) Formate dehydrogenase {Pseudomonas sp., strain 101 [TaxId: 306]}  ali model 3D-neighbors follow..  16  42..............LEAMHVGTVAAGRIGLAVLRRLAPFDVHLHYTDRHRLPESVEKELNLTHATREDMYPVCDVVTLNCPHPETEHMINDETLKLFKRGAYIVNTARGKLCDRDAVARA........................................................................................................................................................................................................................ 149
26 -14.900d1gdha1 c.2.1.4 (A:101-291) D-glycerate dehydrogenase {Hyphomicrobium methylovorum [TaxId: 84]}  ali model 3D-neighbors follow..  16  45..............LDNKTLGIYGFGSIGQALAKRAQGFDMDIDYFDTHRSSSDEASYQATFHDSLDSLLSVSQFFSLNAPTPETRYFFNKATIKSLPQGAIVVNTARGDLVDNELVVAA........................................................................................................................................................................................................................ 152
27 -14.800d2ahra2 c.2.1.6 (A:1-152) Pyrroline-5-carboxylate reductase ProC {Streptococcus pyogenes [TaxId: 1314]}  ali model 3D-neighbors follow..  14  1.................MKIGIIGVGKMASAIIKGLKQTPHELIISGSSLERSKEIAEQALPYASHQDLIDQVDLVILGIKPQLF-----ETVLKPLHFKQPIIMAAGISLQRLATFVGQDLPLLRIMPNMNA-------QILQSSTA-LTGNALVSQELQARVRDLTDSFGSTF................................................................................................................................................................. 148
28 -14.800d1sc6a1 c.2.1.4 (A:108-295) Phosphoglycerate dehydrogenase {Escherichia coli [TaxId: 562]}  ali model 3D-neighbors follow..  18  42..............ARGKKLGIIGYGHIGTQLGILAESLGMYVYFYDIEN---KLPLGNATQVQHLSDLLNMSDVVSLHVPNPSTKNMMGAKEISLMKPGSLLINASRGTVVDIPALADA........................................................................................................................................................................................................................ 145
29 -14.600d3tria1 c.2.1.0 (A:2-162) automated matches {Coxiella burnetii [TaxId: 777]}  ali model 3D-neighbors follow..  20  1...............NTSNITFIGGGNMARNIVVGLIANGYRICVTNRSLDKLDFFKEKGVHTTDNRQGALNADVVVLAVKPHQIKMVC-EELKDILSETKVISLAVGVTTPLIEKWLGKASRIVRAMPNTPS-------SVRAGATGLFA--ETVDKDQKNLAESIMRAVGLVI................................................................................................................................................................. 158
30 -14.500d1mx3a1 c.2.1.4 (A:126-318) Transcription corepressor CtbP {Human (Homo sapiens), Ctbp1 [TaxId: 9606]}  ali model 3D-neighbors follow..  16  47..............IRGETLGIIGLGRVGQAVALRAKAFGFNVLFYDPYLSDGVERALGLQRVSTLQDLLFHSDCVTLHCGNEHNHHLINDFTVKQMRQGAFLVNTARGGLVDEKALAQA........................................................................................................................................................................................................................ 153
31 -14.400d1ygya1 c.2.1.4 (A:99-282) Phosphoglycerate dehydrogenase {Mycobacterium tuberculosis [TaxId: 1773]}  ali model 3D-neighbors follow..  19  42..............IFGKTVGVVGLGRIGQLVAQRIAAFGAYVVAYDP--VSPARAAQLGIELLSLDDLLARADFISVHLPTPETAGLIDKEALAKTKPGVIIVNAARGGLVDEAALADA........................................................................................................................................................................................................................ 147
32 -14.400d1xc2a3 c.2.1.6 (A:1-152) Pyrroline-5-carboxylate reductase ProC {Neisseria meningitidis, serogroup B [TaxId: 487]}  ali model 3D-neighbors follow..  16  1.................MNVYFLGGGNMAAAVAGGLVKQG-RIYIANRGAEKRERLEKEGVETSATLPELHSDDVLILAVKPQDMEAACKN----RTNGALVLSVAAGLSVGTLSRYLGGTRRIVRVMPNTPG-------KIGLGVSGMYA--AEVSETDRRIADRIMKSVGLTV................................................................................................................................................................. 149
33 -14.400d1l7da1 c.2.1.4 (A:144-326) Nicotinamide nucleotide transhydrogenase dI component {Rhodospirillum rubrum [TaxId: 1085]}  ali model 3D-neighbors follow..  17  27..............VPPARVLVFGVGVAGLQAIATAKRLGAVVMATDVRAATKEQVESLGGKFITVLKELVKTDIAIALIPGKPAPVLITEEMVTKMKPGSVIIDLA..................................................................................................................................................................................................................................... 151
34 -14.400d1evya2 c.2.1.6 (A:9-197) Glycerol-3- phosphate dehydrogenase {Trypanosome (Leishmania mexicana) [TaxId: 5665]}  ali model 3D-neighbors follow..  16  1..........KDELLYLNKAVVFGSGAFGTALAMVLSKKCREVCVWHMNEEEVRLVNEKRENTSDVEKAYNGAEIILFVIP-TQFLRGFFEKSGGNLIAYAVLVCTKGIERSTLKFPAEIIGEFLPSPLLSAGPSFAIEVATGVFTCVSIASADINVARRLQRIMS.......................................................................................................................................................................... 178
35 -14.400d2g5ca2 c.2.1.6 (A:30-200) Prephenate dehydrogenase TyrA {Aquifex aeolicus [TaxId: 63363]}  ali model 3D-neighbors follow..  14  2.................QNVLIVGVGFMGGSFAKSLRRSGFKIYGYDINPESISKAVDLGITTSIAKVEDFSPDFVMLSSPVRTFREIA-KKLSYILSEDATVTDQGSVKGKLVYDLENILGKRFVGGHPIAGTEKSGVEYS-EGKKVILTPTKKTDKKRLKLVKRVWEDVGGVVEYM.............................................................................................................................................................. 171
36 -14.300d1e5qa1 c.2.1.3 (A:2-124,A:392-450) Saccharopine reductase {Fungus (Magnaporthe grisea) [TaxId: 148305]}  ali model 3D-neighbors follow..  24  1...............ATKSVLMLGSGFVTRPTLDVLTDSGIKVTVACRTLESAKKLSADVNDDAALDAEVAKHDLVISLIPYTFHATVIKSAI................................................................................................................................................................................................................................................... 88
37 -14.300d3k96a1 c.2.1.0 (A:3-180) automated matches {Coxiella burnetii [TaxId: 227377]}  ali model 3D-neighbors follow..  18  3................KHPIAILGAGSWGTALALVLARKGQKVRLWSYESDHVDEMQAEGVNYCDLKASLEGVTDILIVVP-SFAFHEVITRMKPLIDAKTRIAWGT..................................................................................................................................................................................................................................... 107
38 -13.800d2dapa1 c.2.1.3 (A:1-118,A:269-320) Diaminopimelic acid dehydrogenase (DAPDH) {Corynebacterium glutamicum [TaxId: 1718]}  ali model 3D-neighbors follow..  20  1..............MTNIRVAIVGYGNLGRSVEKLIAKQPDMDLVGIFSRRATLDTKTPVFDVADVDKHADDVDVLFLCMGSATDIPEQAPKFAQFAC.............................................................................................................................................................................................................................................. 84
39 -13.700d5bsea1 c.2.1.0 (A:3-169) automated matches {Medicago truncatula [TaxId: 3880]}  ali model 3D-neighbors follow..  16  6..............ADSYTLGFIGAGKMAESIAKGAVRSGVRIKTAIHSNPARRTAFESGITVLSNDDVVRDSNVVVFSVKPQLLKDVV-LKLKPLLTKDKLLVSVAAGIKMKDLQEWAGHERFIRVMPNTAA-------TVGEAASV-MSLGGAATEEDANLISQLFGSIG.................................................................................................................................................................... 160
40 -13.500d4e12a1 c.2.1.0 (A:1-189) automated matches {Acinetobacter baylyi [TaxId: 202950]}  ali model 3D-neighbors follow..  20  5.................TNVTVLGTGVLGSQIAFQTAFHGFAVTAYDINTDALDAAKKR---SDDLAQAVKDADLVIEAVPESLDLKRDIYTKLGELAPAKTIFATNSSTLLPSDLV........................................................................................................................................................................................................................... 130
41 -13.500d1yjqa2 c.2.1.6 (A:1-167) Ketopantoate reductase PanE {Escherichia coli [TaxId: 562]}  ali model 3D-neighbors follow..  16  1.................MKITVLGCGALGQLWLTALCKQGHEVQGWLRVPQPYCSVNLVETDTANDPDFLATSDLLLVTL-KAWQVSDAVKSLASTLPVTTPILLIHN.................................................................................................................................................................................................................................... 98
42 -13.200d1z82a1 c.2.1.0 (A:2-166) automated matches {Thermotoga maritima [TaxId: 243274]}  ali model 3D-neighbors follow..  25  1................EMRFFVLGAGSWGTVFAQMLHENGEEVILWARRKEIVDLINVSTVRATNDLEEIKKEDILVIAIPVQYIREHLLR..................................................................................................................................................................................................................................................... 86
43 -13.000d2hmta_ c.2.1.9 (A:) Ktn bsu222 {Bacillus subtilis [TaxId: 1423]}  ali model 3D-neighbors follow..  14  1................NKQFAVIGLGRFGGSIVKELHRMGHEVLAVDINEEKVNAYASYATHAVIANATIRNFEYVIVAIGANIQASTLTTLLLKEL--DIPNIWVKAQNYYHHKVLEKIGADRIIHPEKDMGVKIAQSLSD.................................................................................................................................................................................................. 133
44 -12.900d1c1da1 c.2.1.7 (A:149-349) Phenylalanine dehydrogenase {Rhodococcus sp., M4 [TaxId: 1831]}  ali model 3D-neighbors follow..  17  18.......AHRGLGSLDGLTVLVQGLGAVGGSLASLAAEAGAQLLVADTDTERVAHAVALGHTAVALEDVLSPCDVFAPC----AMGGVITTEVARTLDCSVVAGAANN.................................................................................................................................................................................................................................... 115
45 -12.600d2g1ua_ c.2.1.0 (A:) automated matches {Thermotoga maritima [TaxId: 2336]}  ali model 3D-neighbors follow..  25  5.................KYIVIFGCGRLGSLIANLASSSGHSVVVVDKNEYAFHRLNSDAAEFETLKECMEKADMVFAFTNDDST........................................................................................................................................................................................................................................................... 82
46 -12.600d2izza1 c.2.1.0 (A:1-164) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  14  1.................MSVGFIGAGQLAFALAKGFTAAGVKIMASSPDMDLATVSALRKMGVPHNKETVQHSDVLFLAVKPHIIPFIL-DEIGADIEDRHIVVCAAGVTISSIEKKLSPAPRVIRCMTNTPV-------VVREGATV-YATGTHAQVEDGRLMEQLLSSVG.................................................................................................................................................................... 157
47 -12.600d3vpxa2 c.2.1.0 (A:145-363) automated matches {Sporosarcina psychrophila [TaxId: 1476]}  ali model 3D-neighbors follow..  17  27..............LAGKTVAVQGVGNVAYALCEYLHEEGAKLIITDINEEAVQRAVDFGATAVGINEIYSEADIFAPC----ALGAIINDETIPQLKAKVIAGSANN----------QLKETRHGDLIHEMGIVYAPDYVINSG--GVINVADELDGYNRERALKRVEGIYDVIGKIFAISKRDNIPT................................................................................................................................................... 187
48 -12.500d1kjqa2 c.30.1.1 (A:2-112) Glycinamide ribonucleotide transformylase PurT, N-domain {Escherichia coli [TaxId: 562]}  ali model 3D-neighbors follow..  18  5..........TALRPAATRVMLLGSGELGKEVAIECQRLGVEVIAVDRYADAPAMHVAHRSHVINMLDGDALRRVVELEKPHYIVPEIATDMLIQLEEEGLNVV........................................................................................................................................................................................................................................ 101
49 -12.500d3daga1 c.2.1.6 (A:1-242) 5,10-methenyltetrahydromethanopterin hydrogenase, HMD {Methanocaldococcus jannaschii [TaxId: 2190]}  ali model 3D-neighbors follow..  14  39LTHSSITYGAELLHLVPDVSDPCFAEEPGLVIDEFDPKEVMEAHLSGNPESIMPKIREVGLKVTDDREAVEGADIVITWLPKGNKQPDIIKKFADAIPEGAIVTHACTI................................................................................................................................................................................................................................... 178
50 -12.100d1x0va1 c.2.1.0 (A:2-193) automated matches {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  17  1...............ASKKVCIVGSGNWGSAIAKIVGGNDPRVTMWVFEEDIGGKKLTEIINVPDVVQAAEDADILIFVVPHQ-FIGKICDQLKGHLKANAGISLIKGVDEGPNGLKLISEVIGERLGIP-MGANIASEVADEKFCETTIGCKDPAQGQLLKELMQ.......................................................................................................................................................................... 181
51 -12.100d1f0ya2 c.2.1.6 (A:12-203) Short chain L-3-hydroxyacyl CoA dehydrogenase {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  18  5.................KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKG--TSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEHTIFASNTSSLQITSIA........................................................................................................................................................................................................................... 134
52 -12.000d4j0ea1 c.2.1.0 (A:1-198) automated matches {Nematode (Caenorhabditis elegans) [TaxId: 6239]}  ali model 3D-neighbors follow..  22  12.................RNVAIVGSGQMGSGIAQVTASSGFNVMLADVNKKALDRAMKA--TCNNVSTAVADADLIIEAAIENIDLKGIFAQIEQSCKKDSILT........................................................................................................................................................................................................................................ 128
53 -11.800d1lssa_ c.2.1.9 (A:) Ktn Mja218 {Methanococcus jannaschii [TaxId: 2190]}  ali model 3D-neighbors follow..  20  1.................MYIIIAGIGRVGYTLAKSLSEKGHDIVLIDIDKDICKKASADCTKIKTLEDAIEDADMYIAVTGKEEV-NLMSSLLAKSYGINKTIARIS..................................................................................................................................................................................................................................... 99
54 -11.700d2x5oa1 c.5.1.0 (A:1-93) automated matches {Escherichia coli [TaxId: 668369]}  ali model 3D-neighbors follow..  20  3..............YQGKNVVIIGLGLTGLSCVDFFLARGVTPRVMDRMTPPGLDKLPEAVERH--DEWLMAADLIVA.................................................................................................................................................................................................................................................................. 70
55 -11.700d1hdoa_ c.2.1.2 (A:) Biliverdin IX beta reductase {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  18  1..............MAVKKIAIFGAGQTGLTTLAQAVQAGYEVTVLVRDSSRLPSEGPRPAHVVDVDKTVAGQDAVIVLLGPTTVMSEGARNIVAAMKAHGVVVACTSAFLLWDPTKVPPRLQAVTDDHIRMHKVLRESGLK.................................................................................................................................................................................................. 145
56 -11.600d1mv8a2 c.2.1.6 (A:1-202) GDP-mannose 6-dehydrogenase {Pseudomonas aeruginosa [TaxId: 287]}  ali model 3D-neighbors follow..  22  1.................MRISIFGLGYVGAVCAGCLSARGHEVIGVDVSSTKIDLINEPGLETTDFKKAVLDSDVSFICVGDLGYIETVCREIGFAIREKS........................................................................................................................................................................................................................................... 114
57 -11.300d2hk8a2 c.2.1.7 (A:106-266) Shikimate 5-dehydrogenase AroE {Aquifex aeolicus [TaxId: 63363]}  ali model 3D-neighbors follow..  20  16..............VKEKSILVLGAGGASRAVIYALVKEGAKVFLWNRTKEKAIKLAQK--VVNSPEEVIDKVQVIVNTTSVGLKDEDPEIFNYDLIKKDHVVV........................................................................................................................................................................................................................................ 107
58 -11.200d1edza1 c.2.1.7 (A:149-319) Methylenetetrahydrofolate dehydrogenase/cyclohydrolase {Baker`s yeast (Saccharomyces cerevisiae) [TaxId: 4932]}  ali model 3D-neighbors follow..  17  27..............LYGKKCIVINRSEVGRPLAALLANDGATVYSVDVNNNKHHVEDLGEYSEDLLKKCSLDSDVVITGVPSENYK-------TEYIKEGAVCINFA..................................................................................................................................................................................................................................... 127
59 -11.100d3phha2 c.2.1.0 (A:105-263) automated matches {Helicobacter pylori [TaxId: 85962]}  ali model 3D-neighbors follow..  18  8..........SLKQKNYQNALILGAGGSAKALACELKKQGLQVSVLNRSSRGLDFFQRLGCDCFM-EPPKSAFDLIINATS............................................................................................................................................................................................................................................................... 77
60 -10.900d2r6ja_ c.2.1.0 (A:) automated matches {Ocimum basilicum [TaxId: 39350]}  ali model 3D-neighbors follow..  21  3................KSKILIFG-GYIGNHMVKGSLKLGHPTYVFTRPNSSLDEFQSLGAIIVKLVELMKKVDVVISALAFPQILDQFKILEAIKVAGNIKRFLPSDFGV................................................................................................................................................................................................................................. 110
61 -10.900d1uufa2 c.2.1.1 (A:145-312) Hypothetical protein YahK {Escherichia coli [TaxId: 562]}  ali model 3D-neighbors follow..  18  30...............PGKKVGVVGIGGLGHMGIKLAHAMGAHVVAFTTSEAKREAAKALGANADEMAAHLKSFDFILNTVAAPHNLD----DFTTLLKRDGTMTLVG..................................................................................................................................................................................................................................... 124
62 -10.800d3keoa2 c.2.1.0 (A:82-212) automated matches {Streptococcus agalactiae [TaxId: 216495]}  ali model 3D-neighbors follow..  16  2...............STTNVMLVGCGNIGRALLHFHDRNKMQISAFDLDSNDLVGTTEDGIPVYGISTINDDIETAILTVPSTEAQEVADILVKAGIK.............................................................................................................................................................................................................................................. 93
63 -10.800d2d59a_ c.2.1.8 (A:) Hypothetical protein PH1109 {Pyrococcus horikoshii [TaxId: 53953]}  ali model 3D-neighbors follow..  16  9......DEDIREILTRYKKIALVGASRDANIVMKYLLEHGYDVY-----PVNPKYEEVLGRKCYSVLDIPDKIEVVDLFVKPKLTMEYVEQAIKKGAK--VVWFQYNTYNREASKKADEAGLIIV................................................................................................................................................................................................................... 125
64 -10.700d1kyqa1 c.2.1.11 (A:1-150) Bifunctional dehydrogenase/ferrochelatase Met8p, N-terminal domain {Baker`s yeast (Saccharomyces cerevisiae) [TaxId: 4932]}  ali model 3D-neighbors follow..  15  1MVKSL---------LKDKRILLIGGGEVGLTRLYKLMPTGCKLTLVSPDHKSIIPKFGKF-EYLDLENENDAWYIIMTCIPDHPESARIYHLCKERFGKQQLVNVAD..................................................................................................................................................................................................................................... 141
65 -10.700d4ajjc1 c.2.1.0 (C:1-159) automated matches {Norway rat (Rattus norvegicus) [TaxId: 10116]}  ali model 3D-neighbors follow..  9  3LKDQLIVNLLKEEQVPQNKITVVGVGAVGMACAISILMKDLELALVDVIEDKLKGEMMD-IVSSKDYSVTANSKLVIITAGNVNIFKFIIPNVVKYSPQCKLLIVSNPVDI................................................................................................................................................................................................................................. 141
66 -10.700d1gpja2 c.2.1.7 (A:144-302) Glutamyl tRNA-reductase middle domain {Methanopyrus kandleri [TaxId: 2320]}  ali model 3D-neighbors follow..  25  22..............LHDKTVLVVGAGEMGKTVAKSLVDRGVAVLVANRTYERAVELARDAVRFDELVDHLARSDVVVSATA............................................................................................................................................................................................................................................................... 93
67 -10.700d1wdka3 c.2.1.6 (A:311-496) Fatty oxidation complex alpha subunit, middle domain {Pseudomonas fragi [TaxId: 296]}  ali model 3D-neighbors follow..  12  5.................KQAAVLGAGIMGGGIAYQSASKGTPILMKDINEHGIEQGLAE-IRPTLSYGDFGNVDLVVEAVVENPKVKAVLAEVENHVREDAILA........................................................................................................................................................................................................................................ 116
68 -10.700d1lc0a1 c.2.1.3 (A:2-128,A:247-291) Biliverdin reductase {Norway rat (Rattus norvegicus) [TaxId: 10116]}  ali model 3D-neighbors follow..  14  2...........ITNSGKFGVVVVGVGRAGSVRLRDLKDRSAAFLNLIGFVSRRELGSLDEVRQISLEDALRSQDVAYICSESSSHEDY----IRQFLQAGKHVLVEYPMTLSF------AAAQELWELAAQKGRVLHEEHV................................................................................................................................................................................................... 124
69 -10.600d4m1qa1 c.2.1.0 (A:3-144) automated matches {Bacillus selenitireducens [TaxId: 439292]}  ali model 3D-neighbors follow..  17  2...............KTSRVVIIGTGAVGSSYAFSMINQNVEMVLIDLDKRKTEGDAMD--VWAGDYGDCKSADIVVITAGNANIFKGIVDQVMGSGFNGIFIIATNPVDV................................................................................................................................................................................................................................. 124
70 -10.600d1hyha1 c.2.1.5 (A:21-166) L-2-hydroxyisocapronate dehydrogenase, L-HICDH {Lactobacillus confusus [TaxId: 1583]}  ali model 3D-neighbors follow..  23  1................ARKIGIIGLGNVGAAVAHGLIAQGVDYVFIDANEAKVKADQIDFQDAMAN-AALADADVVISTLGTSSMVQSVGTNLKESGFHGVLVVISNPVDV................................................................................................................................................................................................................................. 127
71 -10.600d1nvmb1 c.2.1.3 (B:1-131,B:287-312) Acetaldehyde dehydrogenase (acylating) {Pseudomonas sp. [TaxId: 306]}  ali model 3D-neighbors follow..  18  1.............MNQKLKVAIIGSGNIGTDLMIKVLRN---GAMVGIDAASDGLARAQRMGVTTTYAGVEDIDFVFDATSASAHVQ--NEALLRQAKPGIRLIDLTPAAI................................................................................................................................................................................................................................. 108
72 -10.600d1t2da1 c.2.1.5 (A:1-150) Lactate dehydrogenase {Malaria parasite (Plasmodium falciparum) [TaxId: 5833]}  ali model 3D-neighbors follow..  18  2...............PKAKIVLVGSGMIGGVMATLIVQKNLDVVLFDIVKNMPHGKALD-VSGSNTYDDLAGADVVIVTAGNNKIMIEIGGHIKKNCPNAFIIVVTNPVDV................................................................................................................................................................................................................................. 130
73 -10.500d1rjwa2 c.2.1.1 (A:138-305) Alcohol dehydrogenase {Bacillus stearothermophilus [TaxId: 1422]}  ali model 3D-neighbors follow..  19  27...............PGEWVAIYGIGGLGHVAVQYAKAMGLNVVAVDIGDEKLELAKELGADAKFMKEKVGGVHAAVVTAVSKPAFQ----SAYNSIRRGGACVLVG..................................................................................................................................................................................................................................... 124
74 -10.500d1llda1 c.2.1.5 (A:7-149) Lactate dehydrogenase {Bifidobacterium longum, strain am101-2 [TaxId: 216816]}  ali model 3D-neighbors follow..  15  2.................TKLAVIGAGAVGSTLAFAAAQRGIEIVLEDIAKERVEAEVLD-IDGSDDPEICRDADMVVITAGTVNILKAIMPNLVKVAPNAIYMLITNPVDI................................................................................................................................................................................................................................. 123
75 -10.400d2v6ba1 c.2.1.0 (A:22-164) automated matches {Deinococcus radiodurans [TaxId: 1299]}  ali model 3D-neighbors follow..  19  1.................MKVGVVGTGFVGSTAAFALVLRGSELVLVDRDEDRAQAEAED-RVWHGGHSELADAQVVILTAGNADIFRELVPQITRAAPDAVLLVTSNPVDL................................................................................................................................................................................................................................. 121
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Friedberg I, Godzik A. Fragnostic: walking through protein structure space. Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W249-51.