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Query: IDP04225 gene: ipaB; IpaB, secreted by the Mxi-Spa secretion machinery, required for entry into epithelial cells [Shigella flexneri] CAC05803 [Shigella flexneri], from CSGID

Results of FFAS03 search in SCOP207
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MHNVSTTTTGFPLAKILTSTELGDNTIQAANDAANKLFSLTIADLTANQNINTTNAHSTSNILIPELKAPKSLNASSQLTLLIGNLIQILGEKSLTALTNKITAWKSQQQARQQKNLEFSDKINTLLSETEGLTRDYEKQINKLKNADSKIKDLENKINQIQTRLSELDPESPEKKKLSREEIQLTIKKDAAVKDRTLIEQKTLSIHSKLTDKSMQLEKEIDSFSAFSNTASAEQLSTQQKSLTGLASVTQLMATFIQLVGKNNEESLKNDLALFQSLQESRKTEMERKSDEYAAEVRKAEELNRVMGCVGKILGALLTIVSVVAAAFSGGASLALAAVGLALMVTDAIVQAATGNSFMEQALNPIMKAVIEPLIKLLSDAFTKMLEGLGVDSKKAKMIGSILGAIAGALVLVAAVVLVATVGKQAAAKLAENIGKIIGKTLTDLIPKFLKNFSSQLDDLITNAVARLNKFLGAAGDEVISKQIISTHLNQAVLLGESVNSATQAGGSVASAVFQNSASTNLADLTLSKYQVEQLSKYISEAIEKFGQLQEVIADLLASMSNSQANRTDVAKAILQQTTALast
1 -6.430d1h21a_ a.138.1.3 (A:) Dimeric di-heme split-soret cytochrome c {Desulfovibrio desulfuricans, ATCC 27774 [TaxId: 876]}  ali model 3D-neighbors follow..  8  2...................................................................................................................................................................................................................................................................................RFDQVGGAFGWKPHKLDPKECAQVAYDGYKGFGCGFGAFYSIVGLMGEMLEANKGGIS-ICGALYGAAATFSLFWGRKEVHPMVNELFRAAQGVKGDLPMSASDSVLCHISVSKWCYENTSKQRSERCGRLTADAAFKAAEIINTKIDQGKDFKSTFPMQASVSSCGE......................................................................................................................................... 204
2 -6.310d1vq8o1 c.12.1.1 (O:1-115) Ribosomal protein L18e {Haloarcula marismortui [TaxId: 2238]}  ali model 3D-neighbors follow..  20  7...............................................................................................................................................................................................................................................................LSSLIADLKSAARSSGGAVWGDVAERLEKPRRTHAEVNLGRIERYAQEDETVVVPGKVLG-LQKDVTVAAVDFSGTAETKIDQVGEAVSLEQAIENNPEGSHVR............................................................................................................................................................................................................................. 112
3 -5.850d1u6gc_ a.118.1.2 (C:) Cullin-associated NEDD8-dissociated protein 1 (Tip120) {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  9  683..........................................................................TAAMIDAVLDELPPLISESDMHVSQMAISFLTTLAKVYPSSLSKISGSILNELIGLVRSPLLQGGALSAMLDFFQALVVTGTNNLGYMDLLRMLTGPVYSQSTALTHKQSYYSIAKCVAALTRACPKEGPAVVGQFIQDVKNQLELKSVILEAFSSPSEEVKSAASYALGSISVLPEYLPFVLQEITSQPKRQYLLLHSLKEIISSASVVGLKPYVENIWALLLKHGTRNVVAECLGKLT----TLLPRLKGYLISGSSYARSSVVTAVNCIGDFLKTLEDPDL--VTFNSAAHNKPSLIRDLLDTVLPHLYNETKVRKELIREVE----DIRKAAFECMYTLLDSCLDRLDIFEFLNHVEDGLKDLTFLMLVRLSTLCPSAVLQRLDRLVEPLRATCTTKVKANSVKQEFEKQDELKRSAMRAVAALLT............................................................................ 1182
4 -5.670d4g38a4 d.134.1.0 (A:426-570) automated matches {Escherichia coli K-12 [TaxId: 83333]}  ali model 3D-neighbors follow..  15  16..............................................................................................................................................................................................................................................................................PLAMAEAERFLPSFIDNIDNLMAKHGVSDEHIVMRVTGCPNGCGRAMLAEVGLVGKA-PGRYNLHLGGNRIGTRIPRMYKENITEPE-----ILASLDELIGRWAK--GEGFGDFTVRAGIIRPVLDPARDL.................................................................................................................................................................................. 143
5 -5.610d4xria_ a.118.1.0 (A:) automated matches {Chaetomium thermophilum [TaxId: 759272]}  ali model 3D-neighbors follow..  11  361..........................................................................GSTIIPPVIQFVEHNLRHADWHFRDAAVSAFGAIMDGPEEKVLEVKTGMQPLIAMMEDESIQVRSTAYALGRITEACSEAIDPNTHLEPLIRSLFNGLMNSPKMAASCCWALMNIAERFAGEPGAAQNFNQSVTNLLTVTAPMNGDSTVRTAAYEVLSVFVQNAANDSLSAVASLSVILQRLEETLPLQQQVVSVEDKLILEDMQTSLCTVLQATVQRLDKEIA-------------PQGDRIMQVLLQILSTCGGKSSVPEG----VFAAISALANA------MEEEFAKYMEAFAPFLYNALGNLVSDVTRSLG--ERSQPYCDNFMNYLLGNLRSTTLANQFKPAILQCFGDIASAIGGHFETYLTIVAQVLQQEMIDYVISLREGIMDAWGGIIGAMKTSNKT-NVLQPYVESIFALLNSIANDPNRSEALMRASMGV-IGDLADAYPNGQLADAFRQDWITAMIRETRSNREFGARTIETARWAREQ-------VKRQIAG 865
6 -5.520d1qgra_ a.118.1.1 (A:) Importin beta {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  9  357.......................................................................TCCEDDIVPHVLPFIKEHIKNPDWRYRDAAVMAFGCILEGPEPSQLKVIQAMPTLIELMKDPSVVVRTAAWTVGRICELLPEAAINDVYLAPLLQCLIEGLSAEPRVASNVCWAFSSLAEAAYEAADVADDQEEPATYC--LSSSFELIVQKLLETTDRPDGHQNNLRSSAYESLMEIV-AVQKTTLVIMERLQQVLQMESHIQSTSDRIQFNDLQSLLCATLQNVLRKVQHQDALQISDVVMASLLRMFQSTAG---------------ALMAVSTLVEV------LGGEFLKYMEAFKPFLGIGLKNLVGDLCRALQ--SNIIPFCDEVMQLLLENLGNENVHRSVKPQILSVFGDIALAIGGEFKKYLEVVLNTLQQASQAQVDKSDYDMVDYLNELRESCLE---AYTGIVQGLKGDQENVHPDVMLVQPRVEFILSFIDHIAGDEDHTDGVVACAAGLIGDLCTAFGKDVLKLVEARPMIHELLTEGRRSKTTLARWATKELR. 870
7 -5.470d5o9zv_ a.118.1.2 (v:) Splicing factor 3B subunit 1, HEAT repeats {Human (Homo sapiens) [TaxId: 9606]}  ali model 3D-neighbors follow..  7  276..............................................................................TREVMLILIREFQSPDEEMKKIVLKVVKQCCGTDGVEANYIKTEIKHFWQHRMALDRRNYRQLVDTTVELANKVGAAEIISRIVDDLKDEAEQYRKMVETIEKIMGNLGAADIDHKLEEQLIDGILYAFQEQTTEDSVMLNGFGTVVNALGKRGTVLWRLNNKSAKVRQQAADLISRTAVVMKTCQEEKLMGHGVVLYEYLGEEYPEVLGSILGALKAIVNVIGMHKMTPPIKDLLPRLTPILKNRHEKVQENCIDLVGRIA-----------DRGAEYVSAREWMRICFELLELLKAHKKAIRRATVNTFG-PHDVLATLLNNLKVQERQNRVCTTVAIAIVAETCSPFTVLPALMNEYRV-VQNGVLKSLSFLFEYIGEMGKDYIYAVTPLLEDALMDRDLVHRQTASAVVQHMSLGVYGFGCEDSLNHLLNYVIQAVMGALEGLRVAIGPCRMLQYCLQGLFHPARKVRDVYWKIYNSIYIGSQDA............. 789
8 -5.440d3cuma4 a.100.1.1 (A:163-296) Hydroxyisobutyrate dehydrogenase {Pseudomonas aeruginosa [TaxId: 208964]}  ali model 3D-neighbors follow..  16  4..................................................................................................................................................................................................................................................................................................................AGQVAKVCNNQLLAVLMIGTA-----AMALGVNGLEAKVLAEIMRRSSGGNWALEVYNPWPGVMENAPAS--GFMAQLMAKDLGLAQEAAQASASST--MGSLALSLYRLLLKQGYAERDFSVVQKLFDPT............................................................................................................................................... 133
9 -5.290d1zbsa1 c.55.1.5 (A:108-283) Hypothetical protein PG1100 {Porphyromonas gingivalis [TaxId: 837]}  ali model 3D-neighbors follow..  13  4.................................................................................................................................................................................................................................................................................................................................GIACILGTGSNSCLFDG-PLGYILGDEGSGAVLGRLFIGSLLKGQMEGLCEAFLQEYGLTSADIIESVYRKPFPNRFLAGFSPFIAQHLDIPAVYSLVQNSFDDFLVRNVLRYNRSVAFHYREVLSSVIKKRGLTLGSVLQSPMEGL................................................................................................................ 167
10 -5.230d3ea5b_ a.118.1.1 (B:) automated matches {Baker`s yeast (Saccharomyces cerevisiae) [TaxId: 4932]}  ali model 3D-neighbors follow..  10  2.......................................................................................................................................................................................................................STAEFAQLLENSILSPDQNIRLTSETQLKKLDNFLQFAGLSSQVLIDENTKLEGRILAALTLKNELVSKDSVKTQQFAQRWITQVSPEAKN-----QIKTNALTALVSIEPRIANAAAQLIAAIADIELLMKIMVDNTGAEQ---LALGYMCESASQALVSSSNNILIAIVQGAQSTETSKAVRLAALNALADSLIFIKNNMEREGERNYLMQVVCEATQAEDIEVQAAAF-GCLCKIMSKYYTFMKPYMEQALYALTIATMKSPNDKVASMTVEFWSTICEEEIDIAY............................................................................ 302
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 2 6 8   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Friedberg I, Godzik A. Fragnostic: walking through protein structure space. Nucleic Acids Res. 2005 Jul 1;33(Web Server issue):W249-51.