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Query: IDP92131 alanyl-tRNA synthetase, putative [Toxoplasma gondii ME49] TGME49_019540 [Toxoplasma gondii ME49], from CSGID

Results of FFAS03 search in SCOP207
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MAMTEEERRAKIEEISAKGKAKGWSGEAVRGAYLEFFEAQGHLIYPSSPVIPRGDNTLLFINAGMNQFKPIFLGQIDRSSPLSKLRRVADTQKCIRAGGKHNDLEDVGKDVYHHTFFEMLGNWSFGDYFKREAIAWAWQLLTEVYKIPKDRLYASYFGGDPRLPSCPPDEEARDIWLQYLPANRVLPFGAKENFWEMADTGPCGPCSEIHYDRIGGRDASSLVNADDPSVLEIWNLVFMQYNREKDGSLTPLPAPCVDTGMGLERVASVLQDKQSNYDTDLFTALFDKILELSPGLRPYGGKVGEEDKDMVDMAYRVLADHARCLTAAIADGAEPSNEGRGYVLRRILRRAVRYARQTLGMAEGNFPKLVPVVVSLLGETFPEMKKNEEKVVRILLKEEQQFSRTLDNGVERFKKVANSLQAKGQKVFPGGEAFTLYSTYGFPLDLTQLMAEEVGLQVDAEEFERKFDAHRAASENTSFKQGGAGAVYALPPDQRHLLAQSRKVPPTDDSAKYEWNVKDQAALMTQDAVEAAPIKAKVMAIWDGKRFAPEVTAVASPTGENLVAVILDKTCFYAEQGGQIGDVGRLVDLSSQAEFEVVDSQKSGDFILHIGSMSKGTLREGTELVPAVDYVRRFRLAQHHTGTHLLNFALREVLIRKLRSGGKASANGDKREDTNGIRICESCLNEKELEDGEDIQQKGSLVEVKRLRFDYAGEKPLENEDIIAVENVVKDCIAQARPVHYKEVPLEQAMKIPGLRAVFGEVYPDPVRVVSVGEDIESLVALADSSQPETPFASIELCGGTHLHNASQLSDFCILSEESVAKGVRRVVAAAGDAAFEARKELEELEEAFRSLASAPRELAALEKEVAKARGLLDGAGPLPLVGKRSLVKQLEQAQKALLELQKARSKELVKEAKKLGEELGTEHKTKPFLVLNLPQLLGDGKALDAASQTLHQAAPDLPFLLVTASAATGTAAIAFVPAACSQLHAASWLTACVGLLGGKGGGKGERAVGAAKEGAADKVDAAVAEATAFAEKKYGALast
1 -108.000d1yfsa2 d.104.1.1 (A:1-236) Alanyl-tRNA synthetase (AlaRS) {Aquifex aeolicus [TaxId: 63363]}  ali model 3D-neighbors follow..  53  1......................SLSAHEIRELFLSFFEKKGHTRVKSAPLVPENDPTLLFVNAGMVPFKNVFLGLEKRP-----YKRATSCQKCLRVSGKHNDLEQVGYTSRHHTFFEMLGNFSFGDYFKKEAIEYAWEFVTEVLKLPKEKLYVSVYKDDEEAYRIWNEH-------IGIPSERIWRLGEEDNFWQMGDVGPCGPSSEIYVDRGEE-------YEGDERYLEIWNLVFMQYNRDENGVLTPLPHPNIDTGMGLERIASVLQGKNSNF........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 236
2 -64.600d1yfsa1 a.203.1.1 (A:237-453) Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) {Aquifex aeolicus [TaxId: 63363]}  ali model 3D-neighbors follow..  39  1.....................................................................................................................................................................................................................................................................................EIDIIFPLIQFGEEVSGKKY--------GEKFETDVALRVIADHLRAITFAISDGVIPSNEGRGYVIRRILRRAMRFGYK-LGIENPFLYKGVDLVVDIMKEPYPELELSREFVKGIVKGEEKRFIKTLKAGMEYIQEVIQKALEEGRKTLSGKEVFTAYDTYGFPVDLIDEIAREKGLGIDLEGFQCELEEQRERARKHFKVEAK.......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 197
3 -57.500d1j5wa_ d.104.1.1 (A:) Glycyl-tRNA synthetase (GlyRS) alpha chain {Thermotoga maritima [TaxId: 2336]}  ali model 3D-neighbors follow..  17  1.......................MYLQDVIMKLNDFWASKGCLLEQPYDME-----------VGAGTFHPTFFGSLRKGP-----WKVAYVQPSRR----PTDGR------YGENPNRLQRYFQYQVIIKPNSQELYLESLEY-LGINLKEHDIRF----------------------------------VEDNWESPTLGAWGVGWEVWLD------------------MEITQFTYFQQIGG-----ISLKDIPLEITYGLERIAMYLQGVDNVYEVQWNENVKYGDVFLENEREFSVFNFEEANVGLLFPAYDYILKCSHTFNLLDARGAISVSQRQTYVKR--IQAMARKAARV....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 274
4 -45.900d2e1ba2 d.67.1.2 (A:88-216) AlaX-M trans-editing enzyme, C-terminal domain {Pyrococcus horikoshii [TaxId: 53953]}  ali model 3D-neighbors follow..  25  1....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................DWDYRYKLMRIHTGLHLLEHVLNEVLGEGNWQ------------------------------------LVGSGMSVEKGRYDIAYPENLNKYK-EQIISLFNKYVDEGGEV-----------------KIWWEGD---RRYTQIRD------------------FEVIPCGGTHVKDIKEIGHIKKLKRSSIGRGKQRLEMWL.............................................................................................................................................................................................................. 128
5 -42.400d1v4pa_ d.67.1.2 (A:) Hypothetical protein PH0574 {Pyrococcus horikoshii [TaxId: 53953]}  ali model 3D-neighbors follow..  15  2........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................YSIEVRTHSALHVVKGAVVKVLGSEAKWTY------------------------------------STYVKGNKGVLIVKFDRKPSDEEIREIERLANEKVKENAPIKIYELPREEAEKMFGEDMY--PEDVRILKVVVIED------------------WNVNACNKEHTKTTGEIGPIKIRKRFRKSKGLLEIHFEL.............................................................................................................................................................................................................. 150
6 -30.500d1tkea2 d.67.1.1 (A:63-224) Threonyl-tRNA synthetase (ThrRS), second `additional` domain {Escherichia coli [TaxId: 562]}  ali model 3D-neighbors follow..  11  1..........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................KDEEGLEIIRHSCAHLLGHAIKQLWPHTKMAIGPVI-DNGFYYDVDLDRTLTQEDVEALEKRMHELAEKNYDVIKKKVSWHEARET-FANRGESYKVSILDENIAHDDKPGLYFH----------EEYVDMCRGPHVPNMRFCHHFKLMKTAGANKMLQRIYGTA.............................................................................................................................................................................................................. 160
7 -15.900d2e1ba1 b.43.3.6 (A:1-87) AlaX-M trans-editing enzyme, N-terminal domain {Pyrococcus horikoshii [TaxId: 53953]}  ali model 3D-neighbors follow..  27  26................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................RDNAILLDQTIFYPTGGGQPHDRGTING------VEVLDVYKDEEGNVWHVVKEPEKFKVGDEVELKI......................................................................................................................................................................................................................................................................................................................................................................................................................... 87
8 -7.380d4c2ma_ e.29.1.2 (A:) RNA polymerase I subunit A190 {Baker`s yeast (Saccharomyces cerevisiae) [TaxId: 4932]}  ali model 3D-neighbors follow..  12  429...........................TIQNDVNAFIDSTKAQGRTSGKVPIPGVKQALEKKEGL--FRKHMMG-----------KRVNYAARSVISPDPNIETNEIG--AVKLTYPEPVTAYNIAELRQEQRKALANQLLTPSSNVSTHTLNKKVYNRDVVLMNRQPTLHKASMMVRVLPNEKTLRLHYAN-------------TGAYNADFDGDEMNMHFPQNENAR-AEALNLANTQYLTPTSGSVRGLIQDHISAGV-------WLTSKDSFFTREQYQQYI--------------GCIRPEDGHTTRSKIVTLPPTI----------FKPYPLWTGQIITTVLLNVTPPDMPGINLISK--NKIKNEYWGKGSLENEVLFKDGALLCGIL--DKSQYGASKYGIVHSLHEVYGPEVAAKVLSVLGRLFTNYITATAFTCGMDDLRLTAEGNKWRTDILKTSVDTGREAAAEVNLDKDTPADDPELLKRLQEILRDNNKSGILDAVTSSKVNAITSQVVSKCVGTMKKFPCNSMQAMALSGAKGSNVNVSQIM-EGRRVPVMVSTLPSFAMAGGYVKGSGI----------------KPQEYYFHCMAGREGLIRSGYLQRCLTKQLEGVHVSYDNSIRDADGTLVQFMYGGDCLDNYYALLKKYNPSALIEHLDVESALKYSKKTLKYRKKHSKEPHYKQSVKYDPVLAKYNPAKYLGSVSENFQDKLESFLDKNSKLFKSSDGVNEKKFRALMQLKYGEAVGIISVGEP------------------STQMTLNTHFAGHG---------AANVTLGIPRLREIVMTASAAIK----------TPQMTLPIWNDVSDEQADTFCKSISKVLLSEVIDKVIVTETTGTSNTAGGNAARSYV................................................................................................................................... 1291
9 -7.210d1mswd_ e.8.1.3 (D:) T7 RNA polymerase {Bacteriophage T7 [TaxId: 10760]}  ali model 3D-neighbors follow..  10  328...........................KINKKVLAVANVITKWKHCPVEDIPAIEREEL-NPEALTAWKRAAAAVYRKDKARKSRRISLEFMLEQANKFANHKMDWRGR-VYAVSMFNPQGNLAKGKPIGKEGYYWLKIHGANCAGVDKERI---IEENHENIMACAKSPLENTWWA------------EQDSPFCF-----LAFCFE-----------------------------YAGVQHHGLSYNCSLPLAFDGSCSGIQHFSAMLRDLPSETVQDIYGIVAKKVNEILQ-------ADAINGTDNEVVTVTDENTGEISEKVKLGTKALAGQWLAYGVTRSVTKRSVMYGSKEFGFRQQVLEDTIQPAIDSGKGL-TQPNQAAGYMAKLIWESVSVTVVAAVEAMNWLKSAAKLLAAEVKDKKRKRCAVHWVTPDGFPVWQEYKKPIQTRLNLMFLG-SEIDAHKQESGIAPNFVHSQDGSHLRKTVVWAHEKYGIESFALIHDSF--DAANLFKAVRETMV-YESCDVLADFYDQFADQLHESQLDKMPALPAKGNLNLILESDFAFA............................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 882
10 -6.590d3p8ta_ d.104.1.1 (A:) automated matches {Pyrococcus abyssi [TaxId: 29292]}  ali model 3D-neighbors follow..  13  19..........................TKILDYMTKFFTDRGFKWLLPIMLSPITDPLW--AGEGIRPAEVDVYGVRKQLAIAMGLEKIFVLSPNIRLESRRKD------DGRHSYEFTQL-EIEGAKM--KDVMRLIEELIYGLFRKAEEWT-FKVYDYKDILEEFGSDEKASMFWIVNIPREFYDREENGVWK-GYGEVSSGGEREWEYEKIVAKIRAAGLKEDSFRPYLEIARA----------GKLKP----SAGAGIGVERLVRFIVGAKHIAEVQPFPRVPGIPAVI......................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 294
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Schwarzenbacher R, Godzik A, Jaroszewski L. The JCSG MR pipeline: optimized alignments, multiple models and parallel searches. Acta Crystallogr D Biol Crystallogr. 2008 Jan;64(Pt 1):133-40. Epub 2007 Dec 5.