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Query: gi|16128008|ref|NP_414555.1| chaperone Hsp70, co-chaperone with DnaJ (dnaK b0014 exp) [Escherichia coli str. K-12 substr. MG1655], from E.coli

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MGKIIGIDLGTTNSCVAIMDGTTPRVLENAEGDRTTPSIIAYTQDGETLVGQPAKRQAVTNPQNTLFAIKRLIGRRFQDEEVQRDVSIMPFKIIAADNGDAWVEVKGQKMAPPQISAEVLKKMKKTAEDYLGEPVTEAVITVPAYFNDAQRQATKDAGRIAGLEVKRIINEPTAAALAYGLDKGTGNRTIAVYDLGGGTFDISIIEIDEVDGEKTFEVLATNGDTHLGGEDFDSRLINYLVEEFKKDQGIDLRNDPLAMQRLKEAAEKAKIELSSAQQTDVNLPYITADATGPKHMNIKVTRAKLESLVEDLVNRSIEPLKVALQDAGLSVSDIDDVILVGGQTRMPMVQKKVAEFFGKEPRKDVNPDEAVAIGAAVQGGVLTGDVKDVLLLDVTPLSLGIETMGGVMTTLIAKNTTIPTKHSQVFSTAEDNQSAVTIHVLQGERKRAADNKSLGQFNLDGINPAPRGMPQIEVTFDIDADGILHVSAKDKNSGKEQKITIKASSGLNEDEIQKMVRDAEANAEADRKFEELVQTRNQGDHLLHSTRKQVEEAGDKLPADDKTAIESALTALETALKGEDKAAIEAKMQELAQVSQKLMEIAQQQHAQQQTAGADASANNAKDDDVVDAEFEEVKDKKLast
1 -165.000PF00012.20; HSP7E_DROME/54-653; Hsp70 protein  ali follow..  62  1...VIGIDLGTTNSCLAVMEGKQAKVIENAEGARTTPSHVAFTKDGERLVGMPAKRQAVTNSANTFYATKRLIGRRFDDPEVKKDITNLSYKVVKASNGDAVSSTDGKVYSPSQIGAFILMKMKETAEAYLNTPVKNAVVTVPAYFNDSQRQATKDAGQIAGLNVLRVINEPTAAALAYGMDKT-EDKIIAVYDLGGGTFDISILEIQ----KGVFEVKSTNGDTLLGGEDFDNHIVNFLVAEFKKDSGIDIRKDNIAMQRLKEAAEKAKCELSSSQQTDINLPYLTMDAAGPQHMNLKLTRSKLESLVGDLIKRTIQPCQKALSDAEVSKSEIGEVLLVGGMTRMPKVQSTVQELFGRQPSRSVNPDEAVAVGAAVQGGVLAGDVTDVLLLDVTPLSLGIETLGGVFTRLISRNTTIPTKKSQVFSTASDGQTQVEIKVHQGEREMANDNKLLGSFTLVGIPPAPRGVPQIEVVFDIDANGIVHVSAKDKGTGKEQQIVIQSSGGLSKDEIENMIKKAEEYATADKQKRELIEIVNQGESIVHDTETKMEEFKSQLPAEECEKLKKEIADLRTLLANKDLEEVRKATSSLQQSSLKLFELAYK.................................. 600
2 -56.500PF06723.13; B0BV76_RICRO/10-340; MreB/Mbl protein  ali follow..  20  1.SSGMAIDLGTANTIVYQKNCGIV---------LREPSVIALIKKDGAFVPYAYGHEA-----------KMMLGRTPTDIEAKRP-------------------LKDGVIADFKGAEEMIKYFIRMVHNRRSFFGPTIVICVPSGSTPVERRAIQEAAESAGGRDVYLIEEPMAAAIGAGLPVT-EATGSMIVDIGGGTTEVAVLSLGG---------IVYARSVRVGGDKMDEAIISYIRRHYNLLIGEATAEKIKQEIGTAYVDENAEPRKMEIKGRDLI---------YGIPKEMILNERQIADSLIEPVSQIVEAVKVALEATPPELSSDKGIVLTGGGSLLRNLDFVLSEATKLPVIVADDALSCVALGTGKVLEDFTKLKH........................................................................................................................................................................................................................................................... 331
3 -33.600PF07520.11; Q881L8_PSESM/1-1042; Virulence factor SrfB  ali follow..  16  276....LVLDVGNSRTCGILIENSRVEFAQASFGKEQWPTIARVGVEAGRLSGRRRGTEGSTG----LSSPKRYL-NSYVQTDSEPKATAAPFSHKITKLGQAFYKLKNEQYSRSSLMTFMLAEVLTQALLQINSPLSSIILTVPPGMPQVERSLLNDRLLQALALVWKCMDEATCGQLVYPDKANREHITLASIDIGGGTTDLVITDYSLERGAEQ-EQRFRDSFK-VAGDDILLDIIQRFVQEAILRQQLNLQVFVPLGLRLLKDYETYDPELPSPVAGGVRRIDGGRDGFELGQVVLRIDLPAIHQAFLKGQINLSKILDALCE--VVFQYPCDALLLTGRPSRLPGVQAYIRRKVPLPPGRIVDPKSTAAVGAMLCLLSEQRKVSNFYFPYSTMRHIGKLDENNLVHDMLYRDVIKSDAQGNEFLQLHEPQLDGPQLRVLGK-------TRLGYRQL----NAERWVAAPLYLIELTERGTRKLVGKPTKDGKEACLLLRFRVDGADADRGDAEIIAETLVIDDN-----IESNTGESFDRKDVKLQLYTMLSAEGGASNYWLDS....................................................................... 1038
4 -21.500PF06406.11; Q8L233_SALTM/1-319; StbA protein  ali follow..  15  2...KIFIDDGSTNIKLAWLEDGDVKTL-------ISPNSFKPEWSFSLLDDAAPAN--------EIDGEKFSFDPLSADAVVTTETRY-------QYSDVNVVAIQHALQQTGLKAQPVDVIVTLPISEYLDANNQKNKQNIERKKKNVMREVRVQGSDAFVIRSVSVLPESIPAGFSV-LAGLEGDESLLIVDLGGTTLDVSHVR------SKMTGITKTWCDPNIGVSLITSGVKEQMAVHANTRVS------------------------------SFQADNIIVHRNEPDYLSRRIYNAEQRESIINVINERQKLLIKRVNDVISRFTDYTHVMCVGGGAEI--VAEAVKNLTKVPDERFYSPQFDLVMG........................................................................................................................................................................................................................................................................ 315
5 -17.600PF08841.10; D5XBU6_THEPJ/275-603; Diol dehydratase reactivase ATPase-like domain  ali follow..  15  3.................................................................IQAGAEKVQEVIESAGKLEDVRGEPGTNVGGMIERIRHVMSDLTNQPQDILAVDTFIPQKVQGALAGEFSLENAVGLAAMVKTNKLQMQEIAEKLAGIKVEIAGVEAEMAVRGA-LTTPGSDRPLAILDMGGGSTDAAIIDREGHINSVHLAG---------AGDMVTLLINSELGLDNPGLAEEIKRYPLAKVESLYHIRTEDGSVQFFDKALDPRLFARVVILKEKGVMEPIPVKDSLEKIKLIRQEAKKKVFVTNAVAPHGNIRNVEFVVMVGGSALDFEIPGFISDRLAEYGVV--GPRNAVATGLVL..................................................................................................................................................................................................................................................................... 327
6 -12.900PF11104.8; Q3IJC0_PSEHT/15-354; Type IV pilus assembly protein PilM;  ali follow..  15  1.....GIDIGSHSIKAVLLSETDTGLRLEALAIEPMPKGAMSERT---IQDIEAIGNVITKLKRKLPKSLKEAAVAVSGQTVITKVIFMDVTLSDAE--ESQIEIEADSLIPYPLDEVNLDFEKLSTNAADPSKMNVLLSAARTESVEARVGALEAA----NLVAKVVDVESYALSRAMQLPSDAFNKCVAIVDIGAVLTLVSVVQ----------GDTIYTRDQVFGGDQYTNSIVTYYNKGFDE-------------------AEIGKATGD-------------------------LPPNYTFEVLAPFQTALLQQVRRAVQLTTTGKDQLDYIVLTGGTAMISGFERLLVEELGRNVLQRHRTQFAIATGLALRS................................................................................................................................................................................................................................................................... 339
7 -11.400PF06277.11; A1U010_MARHV/4-476; Ethanolamine utilisation protein EutA  ali follow..  12  4..HSVGIDIGTTTT-----------------------QVIFSRLTMVNRAPVTQVPRYEFVEREIFFQSPVSATPLQEDGTVNV----------------------------PMLQRFIDEQFAAAGIALSDIETGAIIITGETSKVKNAKDTVMGLAERLGDFVVATAGESVIAGRGSGDYSKRNHARVLNIDIGGGTSNYVVFNSGRVEDTACLNI---------GGNLVKT-------------------DPSGAVTKIREPARLVLESLFGEALPESRLS---------ADKLKKVVDCMAQLVVDVILGNHSELAQKLMTPYLKEAGEFDAVFISGGVGTSYYRLKTDDLDPFKWSDVGVQTQQATVIGAGAYSMSLSGSSIWMNVDSLPIRNIPVVEPQIDWEGGEQPPVCQQIVEAAERMDLRLREDNYAIALGRDMPMSYQAVSHTAKEIADYYQEHGNRQSPAIIVTENDLGKVLGMELQPR-IDPQKLLVIDEVRAVTGDYID............................................................................................................................. 452
8 -9.970PF02782.16; Q2K405_RHIEC/276-476; FGGY family of carbohydrate kinases, C-terminal domain  ali follow..  14  41...................................................................................................................................................................................................................................AGQSATGALLDHVVRMHTAGGEPTAALHQKIVARI---AELRAEEGDAFGERIFVLPDFHGNRSPLADLTLDTSFDGLCALYWRSAVAIALGIRNILEKMKEYGYVPDTLHIAGGHVKNQVLMELYSDATGC-KVVVPKMNEAVLLGTAIAASV................................................................................................................................................................................................................................................................. 199
9 -9.800PF13941.6; A4J7Z4_DESRM/5-459; MutL protein  ali follow..  15  1....LLIDFGSTYTKITAVDVEATEVIATAKGLTTVETNILEGLNKALLVKELTVEAARQAALGAGARILGVYAHQLTSSEIEQIDGSCPDIIL-DGGNKETILHNARMLAKTKYGNTIIIAGNKSAADEVQDILLKAGKDVRVTANEPARDAIRATRRAETYIQGVLMPTPAAVLLSTGTEDEAGLGELIVVDIGGATTDIHSVA------EGHPTRSGVT----------EPFTKRTVEGDLGMRVSALSLLESIGSRRLASVTGLPESEVESYVQYVQNRVELLPENGKQWEIDTAMARLATDLAMER-LENVWTPMGAMYIQHGKDLTEVPYLIGTGGVVNHPHPRQILEGALYKQDQPTLRPKQP-------------------FLLDKEYIAVGLEVKPTAALRLAKKY............................................................................................................................................................................................................................... 454
10 -7.710PF17651.1; A0A101J1B1_9EURY/194-354; RACo middle region  ali follow..  11  3..............................................................................................................................................................................................IALDLGTTTIACALVDLES---GIVIAEETTMNKQITYGEEVITRI------------------------------------------------------------AFAMKGDGLRLLQQAAAGSINIAIQRVAETASVDPLDLVEIAVSSNTVMNHLLTGTDPGYLELADADVPRKPFIR---KAASLGINIHPEAYCFCLPNVSRFVGGDAVSGVLSSGLHCG............................................................................................................................................................................................................................... 161
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Luz JG, Hassig CA, Pickle C, Godzik A., Meyer BJ, Wilson IA. XOL-1, primary determinant of sexual fate in C. elegans, is a GHMP kinase family member and a structural prototype for a class of developmental regulators. Genes Dev. 2003 Apr 15;17(8):977-90. Epub 2003 Apr 02.