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Query: gi|16128001|ref|NP_414548.1| predicted transporter (yaaJ b0007 exp) [Escherichia coli str. K-12 substr. MG1655], from E.coli

Results of FFAS03 search in VFDB
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MPDFFSFINSVLWGSVMIYLLFGAGCWFTFRTGFVQFRYIRQFGKSLKNSIHPQPGGLTSFQSLCTSLAARVGSGNLAGVALAITAGGPGAVFWMWVAAFIGMATSFAECSLAQLYKERDVNGQFRGGPAWYMARGLGMRWMGVLFAVFLLIAYGIIFSGVQANAVARALSFSFDFPPLVTGIILAVFTLLAITRGLHGVARLMQGFVPLMAIIWVLTSLVICVMNIGQLPHVIWSIFESAFGWQEAAGGAAGYTLSQAITNGFQRSMFSNEAGMGSTPNAAAAAASWPPHPAAQGIVQMIGIFIDTLVICTASAMLILLAGNGTTYMPLEGIQLIQKAMRVLMGSWGAEFVTLVVILFAFSSIVANYIYAENNLFFLRLNNPKAIWCLRICTFATVIGGTLLSLPLMWQLADIIMACMAITNLTAILLLSPVVHTIASDYLRQRKLGVRPVFDPLRYPDIGRQLSPDAWDDVSQELast
1 -124.000[E] COG1115 Na+/alanine symporter  ali follow..  41  26LTWFVEKVDGPLWD-ITIVTLLGVGLFFTITTGLVQLRLLPRSLREMWSGRSAEGNSLTPFQAFTTGLASRVGVGNIGGVATAIAIGGEGAVFWMWITALIGMSSAFAESSLAQLFKVKEPCGLYRGGPAYYITKGLKAPLLGAAFAVSLIFTFGFAFNAVQANAIVEATNNAWHWNAQYVGWVLVAITAFIIFGGVKRIGAVSAKLVPMMALFYLIIAVIILGMNIHAIPMVISRIVSSAFDFSAMAGGMFGAIFSKAMLMGVKRGLFSNEAGMGSAPNSAASADVK--HPASQGLIQMLGVFVDTIIVCTCTAVIILLSDNYG-NETLKGISLTQHALQYHVGDFGLHFLAAILFLFAYSSIIGNYAYAESNIRFLRN-KPLFIFIFRLMVLFFVYFGAINHANIVWNFADTVMAIMAMINLVAIVLLSPIVWLILRDYQQQIKAGVEPVFKLEQHPTLKRGVDNDIWS..... 492
2 -14.200[E] KOG1287 Amino acid transporters  ali follow..  9  42......................................................KKEISLLNGVSLVVGNMIGSG-VSPKGVLVHTASYGMSLIVWIGGLFSVVGALCYAELGTTITK-------SGASYAYILEAFG-GFIAFIRLWVSLLVVEPTGQAIIAITFANYIIQPSFPSCRLLAAACICLLTFVNCAYVKWGTRVQD----TFTYAKVVALIAIIVMGLVKLCQGHSEHFQDAFEGSSWDMG--------NLSLALYSALFS--SGWDTLNFVTE----EIKNPERN-----LAIGISMPIVTLIYILTNVAYYTVLNISDVLSSDAVAVTFADQTFGMFSWTIPIAVALSCFGGLNASIFASSRLLSMIHIERFTPIPALLFNCTMALIYLIVEDVFQLINYFSFSYWFFVGLSVVGQLYLRWKEPKRPRPL................................... 422
3 -14.200[E] COG1113 Gamma-aminobutyrate permease and related permeases  ali follow..  12  38................................................AHEEGYHKAMGNRQVQMIAIGGAIGTGLFLGAGARLQMAGPALAL-----LICGLFSFFILRALGELVLHRPSSGSFVSYAREFLGEKAA---YVAGWMYFINWAMTGIVDITAVALYMHYWGAFGGVPQWVFALAALTIVGTMNMIGVKWFAEMEFWFALIKVLAIVTFLVVGTVFLGSGQPLDGNTT---GFHLITDNGGFFPHGLL-PALVLIQGVVFA----ASIEMVGTAAGECKDP---QTMVPKAINSVIWRIGLFYVGSVVLLVMLLPWSAYQAGQSPFVT-FFSKLGVPYIGSIMNIVVLTAALSSLNSGLYCTGRILRSMAMGGSAPSFMAKMGILATLVVYVVGVFLNYLVPSRVFEIVLNFASLGIIASWAFIIVCQMRLRKAIKEGKAADV........................ 432
4 -12.600[E] KOG1286 Amino acid transporters  ali follow..  14  24............................................VLTRKKPLEDSNESKLAKVLSAFDLTALGIGSTLGVGVYVLAGGPAVVVSFLIAAIASIFAGLCYAEFGARVPK-------AGSAYIYSYVTIGE--FIAFLIGWNLILEYAIGSASVVKGLSTYLDQLCGNP--LFAFVVTILFSLAIAVGAKESTRVNN----VFTMLNLGVVLFVIIAGLFKVSSSNWSIPKSQVPEGYGDGGFMPYGV-SGIIKGAAVCFYG----IGFDCIATAGEEAK--NPKKS-----FAVIVSLAMIFLAYFGVSTVLTMMLPYFEQDEKAPLPHVFRINGWHVAEYVVSIGAMFGLCSSMMG-AMFPLPRIVFAMSNDGLLFKFLGDI-MLTGILAAVFNLSQLVNMMSIGTLLAYSMVASCVLMLR............................................. 427
5 -12.500[E] COG0833 Amino acid transporters  ali follow..  15  111................................................HKSDSLKKTIQPRHVLMIALGTGIGTGLLVGNGTALVHAGPGLLIGYAIMGSILYCIIQACGEMALVYSNL--TGGYNAYPSFLVDDGFG---FAVAWVYCLQWLCVCPLELVTASMTIKYWTT--SVNPDVFVIIFYVLVITINIFGARGYAEAEFFFNCCKILMMTGFFILGIIIDVGGAGNDGFIGGKGAFNGKHAIDRFKGVAAT------LVTAAFA----GGSEFIAITTAEQSNPRKAIPGAAKQMIYRILFLFLATIILLGFLVPYNSDQLLGSTGGGTKASPYVIAVASHGPHFINAVILLSVLSMANSSFYSSARLFLTLSEQGYAPKVFSYIAMGVSALFAVIAFCAASPKEEQVFTWLLAISGLSQLFTWTAICLSHLRFRRAMKVQGRS.......................... 514
6 -12.000[S] COG3949 Uncharacterized membrane protein  ali follow..  13  7..........................................................SASQLAFVYVGTVVGAGFATGIVEFFLKFGWFGFFGILVSGGMFTLLGAKLMIISKRINAKSYQE---------MNIFLFGATAGRIINVFMLFVLLGVTSVMLSGA-GALFEEQLGMSAQIGMLITIGLSLIVMTRGVKGIFGVNVFVVPLLIIFSMIVVADSFIFSESRNAAQWVWPHRWDWLLSAVSYGALNLSLAQAV-------------------LVPLANEMSSEKVIKKGALI----------GTMLTIVLSASFLSLSTLPDVFLYDIPMAQVVYLFARSVHLIYLLIIFGEVFTSVIGNLYGLEKQVQSFLPVK------SKYIFAAIMITAYITSQ---IGYGRLISTIYPLFGYVSLAFIGALLCKKAPR.................................... 343
7 -11.800[E] COG0531 Amino acid transporters  ali follow..  12  27.........................................................LGAFDLTMLGVGAVVGGG-ILPGQVASVIAGPGIIISFIIAGIACCLAALCYSEFASKLPV-------AGSAYTYSYHVFGE--GVAWILGWSLILEYGLAVAAIASGWSSYMKSLLA----LLAFVVVMVIGILLSFGIRESTRVNN----IMVLVKIAVVVLFIIVGAFYVKPD------TPFLPFGVQG----------VITGASTVFFA----IGFDAVSSAAEEVK--NPQKNMPIGII-----SLAVCTLLYILLVLTGVVPYTDLVGVSAPVAFALQAINQNWIAGLLSVGAIVGMTTVVLV-MSYGGTRLLFAMGRDGLLPKSFSKI-TVMGLIASTVPMEDLAQLINIGTLFAFAMVSVGIFFLRRNPELNQKGF................................... 408
8 -10.600[P] KOG1291 Mn2+ and Fe2+ transporters of the NRAMP family  ali follow..  11  67..................................................................KLWLFTGPGFLMSIAGDLQAGGYSLLWLLMWATAMGLLIQMLSARV----------GVATGRHLAELCRDEYPTWARYVLWSMAELALIGA-DIQEVIGSAIAIQILSRGFLPLWAGVVITASDCFLF-GVRKLEAVFAVLIATMGLSFAWMFGET-----PSGKELMIGILLPRLSSKTIR-GVVGCVI-------MPHNVFLHSALVQSRKIDPKRKSRVQEALNYYLIESSVALFISFMIFVTTVFAKGFYGTEKANNIGLVNAGQYLQEKFGGGLLPILYIWGIGLLAAGQSSTITGTYAGQFIMGGFLNLRMRAVITRSCAIVPTMIVAIVFSLDVLNEWLNVLQSVQIPFALLPLLTLVSK-EEIMGDFKIGP............................... 451
9 -10.400[E] KOG1289 Amino acid transporters  ali follow..  11  48...............................................ADGEVHLRKSFSLWSILGVGFGTNSWFGISTSMVAGISSGGPMMIVYGIIIVALIIGTSLGE--LSSAYPH-------AGGQFWWSLKLAPPKYKRFAAGSVFTSASTTLSVATEVVGMYALTHPEFIPKRWHIFVCLHLFLMFFNCYGKSLPIISSSSLYISLLSFFTITITVLACSHGKFNDAKF------VFATFNNETGWKNGGIAFIV--GLINPAWSFSCLDCATHMAFEVEKPERVIP---------IAIMGTVAIGFVTSFCYVIADLDAVLSSTTGAPILDIYNQALGNKSGAIFLGCLILFTSFGCVIACHTWQARLCRLWSQVNPHTGVPLNAHLMSLLYLASSTAFQSLITGCIAFLLLSYIIPVICLLAKKRNI.......................................... 450
10 -9.470[E] KOG1304 Amino acid transporters  ali follow..  13  51.................................................YQLDDQEGISFVQTLMHLLKGNIGTG-LLGLPLAIKNAG---VLGPISLVFIGIISVHCMHILTLGYSDTVSFAMEVSPWSCLQKQAAWGRSVVDFFLVITQLGFCSVYIVFLAENVKQVHEGFLESKRIYMLCFLPFIILLVFIRELKNLFVLS-----LANVSMAVSLVIIYQYVVRNMPDPHNLPIVAGWKKYPLFFGTA---------------VFAFE-GIGVVLPLENQMKESKRFP---------QALNIGMGIVTTLYVTLATLGYMCFHDEIKGSITLNLPQDVWLYQSVKILYSFGIFV---TYSIQFYVPAEIIIPGITSKFHTKWKQICEFGIRSFLVSITCAGAILIPRLDIVISFVGAVSSSTLALILPPLVEIL...................................... 438
11 -9.360[E] KOG2348 Urea transporter  ali follow..  12  15....................VVGLGLGFAALMIFV-SLKKFNNENQTSEHFNTASHSVRTGLVASAVVSSWTWASTLLTSAQKTYQYGVSGAFWYASGACVQILL----TVLAIELKRKAPNAHTF---LEVVRARCGPIAHGVFLVFAYITNILVMAMLLCGGSAT--ISSVTGMNTVAVCFLLPVGVIITMFGGIKATF-LTDYIHTVIILVILIMFSLATYSADKKIPGKLYDMLKEAGDAHPVAGNAQGSYLTMRSQEGAIFFIINLAGNFGDNGYWQKAIAANPASALPGYILGGLAWFAIPWLAATTMGLVALGTYPNRMSDLEVSEGLVLPYAAIALMGRAGANATLLLVFMAVTSAASAELIAVSSIKQYVRPRATGKELLYTGHASLIVFGFAMSMGYLYLLMGVLVCPAVVPATCVML................................................ 447
12 -9.350[P] COG1914 Mn2+ and Fe2+ transporters of the NRAMP family  ali follow..  10  44..................................................................RLFAFMGPGYMVSVGTDLAGGGYTLLFVIMLSNLMAILLQALAARLGIATGR---------DLAQACRAYYPRPVNFVLWIACELAIIACDLAEVIGTAIALKLLFGIPLIGGAILTALDAFLVLLLM-GFRYLEAFVIALLIIIFSCFAIQIFVAAPPAGTILHSMFVPSSEIVTNPAMLY-GIIGATV-------MPHNLY-----LHSSIVQTRAYERTEKGKRDAIKWATTDSTIALMLALFVNAAILIVSAVAFHNTGHQDVAEIDQAFELLGLGIASILFAVALLASGLNSTVTATLAGQIIMEGFLRLRIPTRGLAIVPVVVVTALYGEKGTGQLLVFSQVILSMQLPFAVVPLVQFVS............................................ 413
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Luz JG, Hassig CA, Pickle C, Godzik A., Meyer BJ, Wilson IA. XOL-1, primary determinant of sexual fate in C. elegans, is a GHMP kinase family member and a structural prototype for a class of developmental regulators. Genes Dev. 2003 Apr 15;17(8):977-90. Epub 2003 Apr 02.