current user: public |
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Query: gi|16128003|ref|NP_414550.1| molybdochelatase incorporating molybdenum into molybdopterin (mog b0009 exp) [Escherichia coli str. K-12 substr. MG1655], from E.coli |
. 10 . 20 . 30 . 40 . 50 . 60 . 70 . 80 . 90 . 100 . 110 . 120 . 130 . 140 . 150 . 160 . 170 . 180 . 190 . | |||||||
# | Score | Template | Links and tools | %id | First | MNTLRIGLVSISDRASSGVYQDKGIPALEEWLTSALTTPFELETRLIPDEQAIIEQTLCELVDEMSCHLVLTTGGTGPARRDVTPDATLAVADREMPGFGEQMRQISLHFVPTAILSRQVGVIRKQALILNLPGQPKSIKETLEGVKDAEGNVVVHGIFASVPYCIQLLEGPYVETAPEVVAAFRPKSARRDVSE | Last |
1 | -71.800 | [H] COG0521 Molybdopterin biosynthesis enzymes | ali follow.. | 77 | 3 | .AVLKIGLVSVSDRASQGVYADQGIPELQAWLEKALCEPFEIETRLIPDEQDRIEQTLCELVDDYHCHLVLTTGGTGPAKRDVTPDATLAVADREMPGFGEQMRQVSLHFVPTAILSRQVGVIRKNSLILNLPGQPKAIKETLEGVKDENGQVIVKGIFSAVPYCLQLINGIYIDTHPDVIESFRPKSARR.... | 192 |
2 | -27.500 | [R] COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA | ali follow.. | 22 | 7 | .QAVRAAMLAIGDELLSGRTKDRNIGHLADVLTAAGID--LKEVRIVPDEEDAIVAALNALR--ANYDYVFTSGGIGPTHDDITADAVSTAFGVPCIHDETALKLLARRGLEFTESRKRMARMPQGSQVYVMAGVPSVFQAMLDNVLPTL............................................. | 171 |
3 | -24.100 | [EH] KOG2644 3`-phosphoadenosine 5`-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes | ali follow.. | 18 | 12 | .QRKTAAILVIGDEILKGTTRDTNSHFLCKRLHKLGVN--IRKISVIGDDISEISREVQSAS--GAYDYVITSGGVGPTHDDKTYLGLAHAFTDQMQFSDEIRQAVNRLEEAVRLATEKLCTIPKMS-VVALPGVPKFCERAFDELQDQLF............................................ | 196 |
4 | -21.900 | [H] COG0303 Molybdopterin biosynthesis enzyme | ali follow.. | 14 | 183 | VRKPVVGIIATGTELLNGKIRNSNASMVYAQAIEAGAT--PLYLGKISDELDKSFAAVKEAM--KKVDFLITTGGVSVGDFDFLPAIYEKL------GADVLFNKVAMRPGSVTTV-----AHANDMLLFGLSGNPSACYVGFELFVKPIIQTWL........................................ | 329 |
5 | -7.920 | [IT] KOG4435 Predicted lipid kinase | ali follow.. | 9 | 65 | .TRPKRVFVLVNVEGNSRGCFDQFNKNALPLFHLAG-----VQVDVVKADNQAQLEALAGAVDTQEADILYVVGGDG-----TIGTVVTGIFRNR-----------EKAQLPVGFYPGGYDNLWLKRMLPSVFENSDDVRHACETAMAVI............................................. | 192 |
6 | -6.550 | [M] COG2825 Outer membrane protein | ali follow.. | 12 | 76 | ....DGSTMKASDRTKLENEVMKQRETFSTKAQAFEQDNRRRQAEERNKILSRIQDAVKSVATKGGYDVVIDANAVAYADSDITADVLKQV........................................................................................................ | 164 |
7 | -6.510 | [S] COG4333 Uncharacterized protein conserved in bacteria | ali follow.. | 6 | 24 | .SKPYTLFIGLNPSYADAEKDDRTLSRCISFAKSWGYGGVYMSDPIGKDNDSHLIRLVSG------AGLVVAAWGNEGRHLKRSTTVRQLL........................................................................................................ | 124 |
8 | -6.430 | [L] COG0323 DNA mismatch repair enzyme (predicted ATPase) | ali follow.. | 16 | 1 | MSHIIELPEMLANQIAAGEVIERPASVVKE---------------LVENAIDAGSSQIIIEIEEAGLKKVITDNGHGIAHDEVE--ALRRHATSKIKNQADLFRIRTLGFRGEALPS--IASVSVLTLLTAVDGASHGTKLVAR................................................... | 127 |
9 | -6.330 | [IT] KOG1116 Sphingosine kinase, involved in sphingolipid metabolism | ali follow.. | 12 | 185 | ADCGKQLLILLNPKSGSGKGRELFQKQVAPLLTEAEVQYDL----QITTHPQYAKEFVRTRRDLTRYSGIVVASGDG-----LFYEVLNGLMERM--------WRRACRELPLGIIPCGSGNGLAKSV................................................................... | 297 |
10 | -5.840 | [Q] COG3155 Uncharacterized protein involved in an early stage of isoprenoid biosynthesis | ali follow.. | 12 | 2 | ITMKKIGVILSGCGVYDGSEIHEAVLTLLA-ISRSGAQAVCFARNVLIEAARITRGEIRPLADAAELDALIVPGGFG-AAKNLSNFASLGSECTVDRELKALAQAMHQAGKPLGFMCIAPAMLPK...................................................................... | 146 |
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9. Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018. Luz JG, Hassig CA, Pickle C, Godzik A., Meyer BJ, Wilson IA. XOL-1, primary determinant of sexual fate in C. elegans, is a GHMP kinase family member and a structural prototype for a class of developmental regulators. Genes Dev. 2003 Apr 15;17(8):977-90. Epub 2003 Apr 02. |