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Query: gi|238922439|ref|YP_002935952.1| hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit (EUBREC_0007) [Eubacterium rectale ATCC 33656], from E.rectale

Results of FFAS03 search in COG1018
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MIREINVSEITAAIKEMCIQANHFLSPDMDKALKAATANEESPLGKKILNQLQENLKIAGEDMIPICQDTGMAVFFIEIGQDVHFTGGVLEDAINEGVRQGYTDGYLRKSVVKDPLIRENTKDNTPAVIHYSIVSGDKVKITFAPKGFGSENMSRVFMLKPADGIEGVKNAILTAVSDAGPNACPPMVVGVGVGGTFEKCAIMAKKALTREAGTHSDIEYVAELEKEMLEKINNLGIGPGGLGGSTTALAVNINTYPTHIAGLPVAVNICCHVNRHVVKELLast
1 -94.300[C] COG1951 Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain  ali follow..  27  2.......EKLQESMYQLIVETSTNLPNDVRRAIAEAKAENAGTRAALSLSTITENIKMADENISPICQDTGMPTFEIKVPVGVNQ--IEMKKAIYAAIEQATKDGKLRPNSVDSLTNSGNNLGEGTPVIHFEQWEEDYIDARLILKGGGCENKNIQYSLPAGRDLDGIRKCIMHSVYQAQGQGCSAGFIGVGIGGDRTTSYSLAKEQLFRKVDDVNPNDDLRKLEEYVLENANKLGIGTMGFGGEATLLGCKVGAMNRLPASFFVSVAYNCWAFRRLGVEL 284
2 -6.070[S] COG5195 Uncharacterized conserved protein  ali follow..  11  1....MEKNSSVDSLARPFRNPNYKAQPRRNRNLRQIIQNDPVQNEPSKFSYSSIEAPPSVLPQPKYCDVTGLLAIYTDPKTRLRYHNKEIYGLIRELPSGADQELKLRSSDVV........................................................................................................................................................................ 115
3 -5.830[S] KOG4137 Uncharacterized conserved protein  ali follow..  13  55.....KPTRRHKSARQLISDENKRINALLTKANKAAESSTAARRLVPKATYFSVEAPPSIRPAKKYCDVTGLKGFYKSPTNNIRYHNAEIYQLIVKPMAPGVDQEYLKLRGANFVLK.................................................................................................................................................................... 166
4 -5.590[S] COG2429 Uncharacterized conserved protein  ali follow..  13  60VTNGMDLEDHRRIQKSIGNRYPITVSMGVGAAETPYDAQRNASRALQSHGGAQSEERKEVLAIDGLVDEGYVQIAHIDI--------NGITETMTDIVPAYDTSFIVNRHFLMKKLIKEGA---------------------LLFFIGGDN----FMSPCNGLEPQGLLRIINEIDDEINV----ALKAGIGKAPTAEKAANLADLAL......................................................................... 232
5 -5.520[I] KOG2818 Predicted undecaprenyl diphosphate synthase  ali follow..  8  63..........................TKTPQHLVLVISPVDAGVDAVLLSRIFDFALDVGIKHVSLYDRRTKGRGYVDMADLCRSTNADTGSCLKWPPVASPSKLENQPKNGQKTNGYVNGSHSPQLQLHQISASDGHALIADVCRELYEDSKTELVQSLLKQKREALTEQISDMLSKRLGFEAPEPELGIVFARQTCTYGLLPWHARFTEFHTHPSGRHFD--VETFASILCKYSRCEQRWG...................................... 277
6 -5.440[S] COG4423 Uncharacterized protein conserved in bacteria  ali follow..  23  1MALNIKDPEVDRLAAELADRLHTSKTAAIRHALSAQLAFLESRAGD........................................................................................................................................................................................................................................... 46
7 -5.220[J] KOG0554 Asparaginyl-tRNA synthetase (mitochondrial)  ali follow..  11  354.LAFADLDDDMACATAYLQYVVKYVLDNCKEDMEFFDTWIEKGIIRRLSDVAEKELQLGYTDAIEILLKANK-----KFDFPVKWGLDLQSEHERYITEEAFGGRPV-PKEIKAFYMRENDDGKTVAAMDMLVPRIGELI-------GGSQREERLEVLEARLDELKLNKESYWWYLDLRRYGSVPH--GFGLGFERLVQFVTGIDNI......................................................................... 552
8 -5.020[K] COG3357 Predicted transcriptional regulator containing an HTH domain fused to a Zn-ribbon  ali follow..  9  10IVSLLTESREPLTIEEIAYMVGEDDKSKIIEDLEHIAKTLRREGKTLLME-VFKSLRVKPPSRCPKCKSEWI................................................................................................................................................................................................................. 89
9 -4.990[J] KOG1697 Mitochondrial/chloroplast ribosomal protein S9  ali follow..  9  213.LSDLDYMQFIRLLEKLLTSQCGAAEEEFVQRFRRSVTLESKKQLIEPVQYDEQGMAFSKSEGK---RKTAKAEAIVKHGSRIKVNGIDYQLYFPITQDREQLMFPFHFVDRL-----------------------GKHDVTCTVSGGGRSAQAGA--------------------------------IRLAMAKALCSFVTEDEVEWMRQAGLLTTDPRVRERKKPGQEGARR............................................... 389
10 -4.980[P] COG4772 Outer membrane receptor for Fe3+-dicitrate  ali follow..  11  1MHKKVLLALTASLICQESLFAKD--KDYTLGKVSTAGKKDRSDYSGQVNLGYSGITAPKSWQDEEVKKYTGSRTV---------ISNKALTQQANQSIEEALQNVP----------------------LQIRNATGVGAMPTIQIRGFGAGGSGHSDATL----------MLVN---------------GIPVYMAPYAHIELDIFPV-----------TFQAIDRDVIKGGGSVQYGPNTYGGIVNIITKPIPNQWENQAAERIT............... 199
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Li W, Jaroszewski L, Godzik A. Sequence clustering strategies improve remote homology recognitions while reducing search times. Protein Eng. 2002 Aug;15(8):643-9.