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Query: gi|238922438|ref|YP_002935951.1| DNA gyrase, A subunit (EUBREC_0006) [Eubacterium rectale ATCC 33656], from E.rectale

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MDDKIFDQIQQVDLKKTMESSYIDYAMSVIASRALPDVRDGLKPVQRRVLYSMVELGNTPDKPHRKCARIVGDTMGKYHPHGDSSIYGALVNMAQDWSMRYTLVDGHGNFGSVDGDGAAAMRYTEARLSKISLELIKDIGKNTVDFEPNFDETEKEPTVLPSRYPNLLVNGTTGIAVGMATNIPPHNLREVVNAVVRLIDNDIEDKETTIDELIDVVKGPDFPTGGIILGTSGIKEAYRTGRGKIRVRAVTNIEPMENGKNRIVVTELPYNVNKARLIEKIAELHKDKKIDGITDLRDETSREGMRIVVELRRDVNPSVVLNLLFKHTQLQDTFGVINLALVNGEPKVLNLYDLLNYYLIHQKDVVTRRTKFDLDKAEARAHIVEGLIIAQDNIDEVISIIRSSQTTQQAKTRLMERFGLTDEQSQAIVDMRLRALTGLEREKLEAEYKELMAQIAQLKAILADEKKLLGVIREEIIAIADKYGDDRKTEIGYDEYDMSMEDLIPETNTVITMTKVGYIKRMSTDNFKAQHRGGKGIKGMETIEDDYIVEMLMTTSHHYLMFFTNTGRVYRIKAYEIPEASRTSRGTAIINLIPLQPDEKITAMIPIKEYEDDKYLFMATRNGIVKKTPIKDYENIRKNGLAAINLREDDKLIEVKVTDNSEDILLFTKFGQCIRFKETDVRSTGRTTMGVIGMNLAPNDVIIAMQTASMGEAVLLVSSNGLGKRTRIDEFTTQNRGGKGVKCYKITEKSGNLVGVKSVENDDELMLITTEGIIIRIQVSDVTVLGRITTGVKLINLKEGVSVASIAKVVEDKTLMPPEEAKEENDESENSDEDSAENNNSHAEAIENNTEALast
1 -66.000PF00521.20; A0A0D1DXS4_USTMA/785-1232; DNA gyrase/topoisomerase IV, subunit A  ali follow..  21  1................................RSIPSAIDGLKPGQRKVMYVMFDRKS---NSELKVNTLVGNVLGQAYHHGEAALSMTIVGLAQNFSNNVNLLEPRGQFGTRGGKDAASGRYIFTALPKIARALFPATDDALLDYLED-DGQKVEPHWYIPVVPQVLLNGAEGIGTGWSTSVPNYNPHEIVANLRRRMAGE-----------------DVVPMKPWYRGFNGDVEEFGPGRFKISGRVT------QIDEKTYEITELPIRTWTSNYKELLEERIVDKIPATIKDYKEYHTESTVNFIVELTAKGQAEIADKGVEAFFKLSCQISTTNMVLFDQDKKYTSAEEILEEFYLLRLSYYQKRKEYLVDQLKLMYDKLSNQARFVQMIISRQLVVSNRKRADIVAELRQKDFISADSDFDYLLNMAIYNLTKEKVDKLLKERDHKEEELKILIGRSPQN................................................................................................................................................................................................................................................................................................................................................................................................... 441
2 -9.320PF05086.12; O15924_DICDI/5-925; Dictyostelium (Slime Mold) REP protein  ali follow..  16  492...................KSVIKFIQLCIVMKELLDFMT------RSINYETFK-------------SIISELLG---------MSERVLNLEQDVKKLKDLLLKKSKKSTIDDESELLSRVSNHRLSK-SDNYLKFVDSITSTLCVEYDSNSIEHKICRSEISRFQPTGDIIKMNSLFSSFTPSNINTVSQQSEEDLKRKYSLMSSDLSGLLKVFSFGDVSNGFSITN-SNLYNRYEEYMGKTRVITAFFFAP-------IQLTNFIFQTDKITNDKNISRQIKSIKIYNRSYINIE--KVGGNTIDSVKSGFSKVVQINS-FTISCLNISFSSVLIS----KNKLNNLSSLVADYYVKSTEL--------LRKADKLEQLLK----------KYIENFQKLNTITETEEDIIEAFDFESSAGDDI........................................................................................................................................................................................................................................................................................................................................................................................................................................ 903
3 -7.310PF09899.9; V4J3D1_9GAMM/276-1132; Putative amidoligase enzyme (DUF2126 topsan)  ali follow..  17  387...........LDLVANLEASAAETGLRIIIEAVTPDIEVNVHPASSSILYEEARLTRLGTEKFMLDGRHTGTGGGNHVTLGGPTPADSLIQSLITYWQHHPSLS-----GTFIGPTSQAPRVDEAR-----DDSLYELA---IAFQQMPKGQIKQPWIVDRVLRNLLVDGRQGLVEFRAFEMPPHARMSLAQMLLLRLHDRFLLPHFVRQDFGDVIC--DLQRAGYAFESAWFEPFFE---GDLITGNGIRMELRGAIEPWHVLGEEVTAQGTSRFVDSSVERMQ--KVNGMTGARHALTCNGRRVPLH-PTGRRGEFVAGVRFKAWNPPSGLH----TIASHNPLVFDVVDLCTYYVSHPGGRAEQRFPVNSYEAESR........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 824
4 -5.960PF03989.13; GYRA_HAEIN/641-686; DNA gyrase C-terminal domain, beta-propeller  ali follow..  47  1.....................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................KFVVMATAGGIVKKIALTEFSRPRSNGIIALNLRDEDELIGVDITD................................................................................................................................................................................................. 46
5 -5.900PF02689.14; HELI_EHV2/2-789; Helicase  ali follow..  15  4...................................................................................................................GAGFILNMTSDSKVRAIVGRIRGLAAKTVPFDSQFDPEDAEGPFLP--FSTFLITGTAG--AGKSTSI--SALYQSLNCLI------TGATAVAAQNLSNGLKT-YCPT---------IYSAFGFKSRHINILPRHGRNAPARDMEGIQRNEL-YWPVISDILGEFTKKKQRGQYEHLTGVIDEAGSHILTAVVLYKSGAVPCVVVGSPTQTDAIQSTYNLTFLMKHEAVSRYVDLNHNWALFINNKRCTLLKTLEYNLDISPRMVDYIDRFVVPKSKILS-TRLFVSHREVKAYLTALHETLSLNQGGATAEADARLFTCPVVCEVFT-DTFNEYREAVNLPGLTVTEWLQKNLCRLSNYSQFIDQDLSAVHIETGEESTKVTYLVKYVKNSYVSLNGK................................................................................................................................................................................................................................................................................................................................................. 450
6 -5.700PF15449.6; F7B3J9_HORSE/1-1249; Retinal protein  ali follow..  12  173....................................DFPEPLVKAHQHA-YTY------------------------LHS--CLCKYEAVLHITHQATQTQELLQPMVSF--------LLLCFDEVNLGEISKDLLQEVREDLA-----WPLKKGEPQGQPDLLQQLLQYTVSKLQVGAVASLTGSFLEGSSSTTASHLGKKLSTKRGADERLLRALPGVQ-EDSGIGADNDSVLLADKLGKCPLSRPLTAKVQPAAQGGTG--TTSRPPGMGKSNPHESLGM--SSRLMDTPSLSEGEDSSLEEEEDTSYPRPRSSPAGPESTFQLHPGRLR---------QAQEMILKMKEAISERIKF---VPLPSGHQDWAEEEERRTAVPPRPSTVSGSRREPERQRRSQSEGCLKSHMEDATLQELRRVQRDLSQRLEAFYTLGTQRQGQGKEQVLHPRAAARRPDNNYRVPPSNTISKLKASFTK.................................................................................................................................................................................................................................................................................................................................................................................. 656
7 -5.580PF02514.16; Q2JMZ0_SYNJB/187-1302; CobN/Magnesium Chelatase  ali follow..  12  714............SLLRALEGEYILPGPGGDPIRVLPTGRN---------IHALDPQSIPTAAAIKSAEIVVERLLAREYPEGTDNIKTYGESLAQVLCL--PKPDALG------------------RVNKVELIPLEELGRPRIDVVVNCSGVFRD------LFVNQM-------AVKLAAAAVPPELNFVRKHALQQAEELGLTLEQAATRVFSNASG-SYSANSSWEDESELREMYLSRKSFAFGSNLPNQQMRQLFEASLKTVDVTFQ--------------LDSSEISLTDVSHYFD-PTKLVQSLRPDGKAPSAYMADT-----------------TTPNAQIRTLSETIRLDA--RTKLLNPKWYEGMLK-----HGYEGVREIAKRLVNTS-SATAGAVDNWIYEETNETFIKDEAMRQRLMNLNPHSFRRIVGSLLEVHGRGY................................................................................................................................................................................................................................................................................................................................................................................................................. 1108
8 -5.570PF00073.20; POLG_CXB4J/358-524; picornavirus capsid protein  ali follow..  11  1.....................................................................................................................................................FDVTPEMN--IPGQVRNLM-------EIAEVDSVVPINNLKANLMTMEAYRVQVRSTDEMGGQIFGFPLQPGASSVLQRTLLGEILNYYTHWSGSLKLTFVFCGSAMATGK--FLLAYSPPGAGAPDSRKNAMLGTH---------IWDVGLQSSCVLCVPW--------ISQTHYRYVVDDKYTASGFISC............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................... 165
9 -5.530PF03033.20; U80A2_ARATH/195-339; Glycosyltransferase family 28 N-terminal domain  ali follow..  19  1.....................................................................IVMLIVGT---RGDVQPFVAIVRLATHANFK-EFVLTAGEFYPLGGDPKVLAGYMVPIQRNQMKDIIYSLLPACKEPDPDSGISFKADAIIPPAYGHTHVAEALKIPIHVFFTMP............................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ 137
10 -5.510PF00305.19; D7SLA9_VITVI/216-884; Lipoxygenase  ali follow..  11  190........................FSRQTL---------AGLNPYSIQLVKEWPLKSTLDPKIYGPPESAITTEIVEREIKGFMTVDEALKQ-KKLFIIDYHDILLPYVSEVRQIKGSRALFFPDNTLKPLAIELVRPPMDGKPQWKQVFTPSWEATGSWLWKLAKTHFLAHDAGYHQLVSHW-THCVTEPY----IIATNRQLSAMHPIYRLLH----PHFNADGIIPGKYSTEISSAAYGLQLISRGIAVEDPSSPHGLKLAIPDYPFANDGLLLWDAISMVKSDAELQAWTEIRTRGHEDKLKTPQDL-----IGIVTTMVWVTSGHHAAVNFGQYAYAGYFP---NRPTIARTNLPSEDPTEEGWRRFLHKPENELLACLPTQLQAAKVL-TVLDVLSSHSPDEEYLGEHLEPAWGADPLIKAAFE------------RFSGRLKEIEGIIDARNEDKNLKNRH................................................................................................................................................................................................................................................................................................................................................................................................ 657
FFAS is supported by the NIH grant R01-GM087218-01
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Igarashi Y, Eroshkin A, Gramatikova S, Gramatikoff K, Zhang Y, Smith JW,Osterman AL, Godzik A. CutDB: a proteolytic event database. Nucleic Acids Res. 2007 Jan;35(Database issue):D546-9. Epub 2006 Nov 16.