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Query: gi|238922443|ref|YP_002935956.1| transcription repressor of fructose operon FruR (EUBREC_0017) [Eubacterium rectale ATCC 33656], from E.rectale

Results of FFAS03 search in PfamA32U
Master-slave alignment(slide right to see more) does not show gaps in the query sequence, use ali links to display alignment between query and templates.
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# Score Template Links and tools%idFirst MLAEDRCKKILDILDSMGSVTVQQLMDELDTSESTIRRDLVAMDKKGYLTKVHGGAIVNNTNIHTQDEKVINRLKQNRNEKEQIARYAASLIVDNDFVYIDAGTTTAVMIDYITAKNVVFVTNSLTNAKRISDRGYTVYILGGEFKSTTEAIVGDEAVVTLDKYNFTKGFWGTNGITVKNGFTTPEIKEAMVKKKSMENSKEKYILADDSKFSQVSSIKFADFEDAVIITNALSNDNYKKYKNIKEVLast
1 -58.400PF00455.22; A9CFA5_AGRFC/78-235; DeoR C terminal sensor domain  ali follow..  26  1...........................................................................VNIDKKRAIARKAVDLCNDGDAIILNGGTTTFQMVHYMAARRLQVMTNSFAIAEHLVKSKCNVNVPGGAIYRDQSLILSPFENDAIRNFYARRIFLGAQGVG-ALGIMESDALVIQSEQKLMRQAEELIVMVDSSKFRKRSSLILCPLENVTIITDD............... 158
2 -32.500PF06163.11; A0A070SGS2_ECOLX/1-127; Bacterial protein of unknown function (DUF977 topsan)  ali follow..  11  8EQREELKARIIGLVRKNERMTISQLERATGAGWHSVRRCLVDVLACGDLYMPGKYGVFTSEQ-VYRVWRKAAEKATDQTLIRKLPDGEIRRYDRQQNIICGECRKSEVMLRVL-----AFYQGNFQ......................................................................................................................... 127
3 -31.300PF10007.9; A4YIE5_METS5/9-101; Uncharacterized protein conserved in archaea (DUF2250 topsan)  ali follow..  10  4LIEDKRYLMVLQHLRKANVDYGKSIMLNTKIPIEEVVIILDKLENLGLIERVKGATLKNTEA--KFKLSSEVHKHHTYYSLTRAGDHLLRYL........................................................................................................................................................... 93
4 -27.800PF08220.12; ULAR_ECOLI/6-62; DeoR-like helix-turn-helix domain  ali follow..  35  1.....RHQILLEMLAQLGFVTVEKVVERLGISPATARRDINKLDESGKLKKVRNGAEAITQQ......................................................................................................................................................................................... 57
5 -18.800PF09012.10; Q6LTA5_PHOPR/2-67; FeoC like transcriptional regulator  ali follow..  16  3.......QQLKQYIEQHGRSSRSNLATHFGMSADGVEAMLAVWIRKGLIGKELVGC............................................................................................................................................................................................... 51
6 -12.900PF01316.21; ARGR_BACLD/1-70; Arginine repressor, DNA binding domain  ali follow..  27  1MNKGQRHIKIREIITANEIETQDELVDILNVTQATVSRDIKELH........................................................................................................................................................................................................... 49
7 -12.500PF09904.9; A4XY65_PSEMY/5-95; Winged helix-turn helix  ali follow..  16  5..SFYRRLYLAWLIDSGQATSIPALMAATGMPRRTAQDTLAALEELDIDCR.................................................................................................................................................................................................... 53
8 -12.000PF04703.12; Q9ADX3_ECOLX/1-62; FaeA-like protein  ali follow..  16  2......KDNILTFLTELKTCRTTEIAIHFGLSAYQARYYLMNLEKEGKIKRSPVRR............................................................................................................................................................................................... 52
9 -11.900PF03444.15; Q6M165_METMP/2-80; Winged helix-turn-helix transcription repressor, HrcA DNA-binding  ali follow..  22  3...TIVQKEILQELEKNKAVKGTEIAVKLSRNPGTIRNQMQALRALNLVDGPKGGYIPTSL.......................................................................................................................................................................................... 68
10 -11.800PF08280.11; Q8DP24_STRR6/14-73; M protein trans-acting positive regulator (MGA) HTH domain  ali follow..  16  3..KVQRQLRLMETLQNRNWMKLHELAEKLGCTERILKSDLNELRI.......................................................................................................................................................................................................... 46
11 -11.800PF02295.17; DSRAD_HUMAN/295-359; Adenosine deaminase z-alpha domain  ali follow..  18  3...AEIKEKICDYLFNVSDSSALNLAKNIGLKARDINAVLIDMERQGDVYR.................................................................................................................................................................................................... 51
12 -10.800PF01978.19; Q8TXT4_METKA/25-102; Sugar-specific transcriptional regulator TrmB  ali follow..  19  17.........KLLENSEEAPFTVEDVAEIINRSRSTAQKMLQSLVRVGMVER.................................................................................................................................................................................................... 58
13 -10.700PF08279.12; Q82YX2_ENTFA/90-148; HTH domain  ali follow..  22  1.....RVSYIIKLIEEDQFISTYDLSEELAVSRGTVNKDIKRMKE.......................................................................................................................................................................................................... 41
14 -10.500PF00392.21; A6T6K9_KLEP7/13-76; Bacterial regulatory proteins, gntR family  ali follow..  28  28......................AELVAQFGFSRMTINRALRELTDEGLLVRLQG................................................................................................................................................................................................. 59
15 -10.100PF01047.22; YDGJ_BACSU/52-110; MarR family  ali follow..  15  5......RLELLTLLYHADEISQSDLQKKVNIDSAAVTRHLKQLESKGMVSR.................................................................................................................................................................................................... 49
16 -9.700PF17782.1; A0A142LH30_9PROT/300-360; DprA winged helix domain  ali follow..  21  11...EDDAAPLLLALGFD-PVSIDEISNRTTLSASSLVAQLMELEINGRVAQLPGG................................................................................................................................................................................................ 61
17 -9.560PF13601.6; Q7MSY5_PORGI/4-83; Winged helix DNA-binding domain  ali follow..  17  2......RLAIMSVLMSVEEADFLYLKEVTGATSGNISVQLDKLSTAGYIEI.................................................................................................................................................................................................... 46
18 -9.280PF03297.15; Q57XX0_TRYB2/10-110; S25 ribosomal protein  ali follow..  16  38MFDKETMDKLMKEVPKYKVITPSIISDRLKISVALAGKGLQHLCRQGLIRLVSCS................................................................................................................................................................................................ 92
19 -9.240PF07789.12; Q8X8R9_ECO57/105-259; Protein of unknown function (DUF1627 topsan)  ali follow..  20  1.............IEQRGPQTADELATLFGTTSRKVASTLAMAISKGRLIRVNQNG............................................................................................................................................................................................... 43
20 -9.210PF07900.11; Q8TH36_METAC/30-238; Protein of unknown function (DUF1670 topsan)  ali follow..  15  78.....LDKRIMRISTQGALLTQADIAILLGESTKTISRHIEALEENGELVPTRG--KWKDIGPGVSHKKRILELYLKGYEYTEIERKTQHSGEAIMRYVKDFARILVLTEEGFEDEELRIITG---LSEKTIQEYKEL............................................................................................................. 209
21 -9.180PF09182.10; Q8YAD9_LISMO/4-72; Bacterial purine repressor, N-terminal  ali follow..  20  2..RSERLIDMTQFLHPRKLVPLTMFAERYGSAKSSISEDLVIIKK.......................................................................................................................................................................................................... 46
22 -9.170PF12116.8; R6MYF3_9CLOT/3-82; Stage III sporulation protein D  ali follow..  17  4...EERAIELGEYIIESK-ATVRKAAKKFGVSKSTVHKDVAELEINKAQRHIRGGLATKQK.......................................................................................................................................................................................... 76
23 -9.130PF05732.11; O50587_SELRU/6-169; Firmicute plasmid replication protein (RepL)  ali follow..  23  64.........LINNLNRDNVLTQRKIAEKTGISLETVRQTMKALMESGFLIKINSGAYCVN........................................................................................................................................................................................... 116
24 -9.100PF05491.13; R7FLP2_9CLOT/266-337; RuvB C-terminal winged helix domain  ali follow..  12  5...DEIDRKYLECLIVRRPVGLNAIASAIGEEATSLEDVYEPLIKEGLINRTSRGRMATLK.......................................................................................................................................................................................... 66
25 -9.030PF14947.6; E6N974_9ARCH/5-85; Winged helix-turn-helix  ali follow..  14  10........DILESINQQGHAKPTKILLDANLSYDRLVKYLDMLVEKKLVERVENS................................................................................................................................................................................................ 56
26 -9.010PF12840.7; B8EL50_METSB/15-76; Helix-turn-helix domain  ali follow..  9  7LSDKTRYEILKRLGAQTDALACVSVRDCMGVNPATLSHHMKELELAGLIDVTREG................................................................................................................................................................................................ 61
FFAS is supported by the NIH grant R01-GM087218-01
1 4 8 0 6 0   jobs submitted since Jan 1, 2011
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Selected papers from Godzik Lab
Ying Zhang, Ines Thiele, Dana Weekes, Zhanwen Li, Lukasz Jaroszewski, Krzysztof Ginalski, Ashley Deacon, John Wooley, Scott Lesley, Ian Wilson, Bernhard Palsson, Andrei Osterman, Adam Godzik. Three-Dimensional Structural View of the Central Metabolic Network of Thermotoga maritima. Science. 2009 Sep 18;325(5947):1544-9.

Mayya Sedova, Mallika Iyer, Zhanwen Li, Lukasz Jaroszewski, Kai W Post, Thomas Hrabe, Eduard Porta-Pardo, Adam Godzik Cancer3D 2.0:: interactive analysis of 3D patterns of cancer mutations in cancer subsets. Nucleic Acids Research, gky1098 2018; Published on November 8 2018.

Schwarzenbacher R, Godzik A, Jaroszewski L. The JCSG MR pipeline: optimized alignments, multiple models and parallel searches. Acta Crystallogr D Biol Crystallogr. 2008 Jan;64(Pt 1):133-40. Epub 2007 Dec 5.